Hans-Peter Brunner-La Rocca

Professor

Prof. Hans-Peter Brunner-La Rocca has graduated in medicine at the University of Zurich, Switzerland. He was trained in Internal Medicine and Cardiology in Switzerland. After doing a post-doc in Melbourne, Australia, for two years, he had been working as cardiologist and heart failure specialist in Zurich. In 2002, he moved to Basel, where he was responsible for the heart failure and heart transplant services. He has obtained his lecture qualification both in Zurich and in Basel and was announced as Professor in Basel Switzerland in 2008. Since 2009, he has been working at Maastricht UMC+ as Professor of Clinical Heart Failure. He is head of the heart failure clinic and head of the division of structural heart diseases.

He has been involved in numerous research projects since many years. In particular, he has a special interest in personalised medicine in heart failure using biomarkers and has successfully led international studies related to this topic. In addition, eHealth is an important focus of research. He has published >250 research articles.

He has been working as member of different working groups of the Heart Failure Association of the European Society of Cardiology and is board member of working group on heart failure in the Netherlands.

On the one hand, he is continuing his research on biomarker in heart failure for therapy guidance. He is collaborating internationally on this topic and is participating in several large international projects in this regard. On the other hand, he is leading an international consortium, aiming to develop a personalized eHealth application to enable patients with heart failure to perform self-care, i.e. including self-prescription of medication. Recently, the consortium received 4.4 M€ to support this project from INTERREG-NWE (budget Maastricht UMC+ > 2.0 M€).

He is additionally involved in national research projects (e.g. heart-brain connection, supported by CVON) and is the local PI of several large industry sponsored RCTs. In one of them, he is the national coordinator for the Netherlands.

Department of Cardiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 3.B2.031
T: +31(0)43 387 70 97

  • 2020
    • Stienen, S., Ferreira, J. P., Kobayashi, M., Preud'homme, G., Dobre, D., Machu, J.-L., Duarte, K., Bresso, E., Devignes, M.-D., Andres, N. L., Girerd, N., Aakhus, S., Ambrosio, G., Brunner-La Rocca, H.-P., Fontes-Carvalho, R., Fraser, A. G., van Heerebeek, L., de Keulenaer, G., Marino, P., ... Rossignol, P. (2020). Sex differences in circulating proteins in heart failure with preserved ejection fraction. Biology of Sex Differences, 11(1), Article 47. https://doi.org/10.1186/s13293-020-00322-7
    • Harjola, V. P., Parissis, J., Bauersachs, J., Brunner-La Rocca, H. P., Bueno, H., Celutkiene, J., Chioncel, O., Coats, A. J. S., Collins, S. P., de Boer, R. A., Filippatos, G., Gayat, E., Hill, L., Laine, M., Lassus, J., Lommi, J., Masip, J., Mebazaa, A., Metra, M., ... Yilmaz, M. B. (2020). Acute coronary syndromes and acute heart failure: a diagnostic dilemma and high-risk combination. A statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 22(8), 1298-1314. https://doi.org/10.1002/ejhf.1831
    • Raafs, A. G., Linssen, G. C. M., Brugts, J. J., Erol-Yilmaz, A., Plomp, J., Smits, J. P. P., Nagelsmit, M. J., Oortman, R. M., Hoes, A. W., & Brunner-La Rocca, H. P. (2020). Contemporary use of devices in chronic heart failure in the Netherlands. Esc heart failure, 7(4), 1771-1780. https://doi.org/10.1002/ehf2.12740
    • Linssen, P. B. C., Brunner-La Rocca, H.-P., Schalkwijk, C. G., Beulens, J. W. J., Elders, P. J. M., Van der Heijden, A. A., Slieker, R. C., Stehouwer, C. D. A., & Henry, R. M. A. (2020). Serum Matrix Metalloproteinases and Left Atrial Remodeling-The Hoorn Study. International journal of molecular sciences, 21(14), Article 4944. https://doi.org/10.3390/ijms21144944
    • Ferro, D., van den Brink, H., Amier, R., van Buchem, M., de Bresser, J., Bron, E., Brunner-La Rocca, H.-P., Hooghiemstra, A., Marcks, N., van Rossum, A., Biessels, G. J., & Heart-Brain Connection Consortium (2020). Cerebral cortical microinfarcts: A novel MRI marker of vascular brain injury in patients with heart failure. International Journal of Cardiology, 310, 96-102. https://doi.org/10.1016/j.ijcard.2020.04.032
    • Brunner-La Rocca, H.-P., Peden, C. J., Soong, J., Holman, P. A., Bogdanovskaya, M., & Barclay, L. (2020). Reasons for readmission after hospital discharge in patients with chronic diseases-Information from an international dataset. PLOS ONE, 15(6), Article 0233457. https://doi.org/10.1371/journal.pone.0233457
    • Linssen, P. B. C., Veugen, M. G. J., Henry, R. M. A., van Der Kallen, C. J. H., Kroon, A. A., Schram, M. T., Brunner-La Rocca, H.-P., & Stehouwer, C. D. A. (2020). Associations of (pre)diabetes with right ventricular and atrial structure and function: the Maastricht Study. Cardiovascular Diabetology, 19(1), Article 88. https://doi.org/10.1186/s12933-020-01055-y
    • Veenis, J. F., Brunner-La Rocca, H. P., Linssen, G. C. M., Smeele, F. J. J., Wouters, N. T. A. E., Westendorp, P. H. M., Rademaker, P. C., Hemels, M. E. W., Rienstra, M., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2020). Atrial fibrillation in chronic heart failure patients with reduced ejection fraction: The CHECK-HF registry. International Journal of Cardiology, 308, 60-66. https://doi.org/10.1016/j.ijcard.2020.03.001
    • Linssen, G. C. M., Veenis, J. F., Brunner-La Rocca, H. P., van Pol, P. E. J., Engelen, D. J. M., van Tooren, R. M., Koornstra-Wortel, H. J. J., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2020). Differences in guideline-recommended heart failure medication between Dutch heart failure clinics: an analysis of the CHECK-HF registry. Netherlands Heart Journal, 28(6), 334-344. https://doi.org/10.1007/s12471-020-01421-1
    • Simonavicius, J., Puronaite, R., & Brunner-La Rocca, H. P. (2020). The Reply. American Journal of Medicine, 133(6), E330-E332. https://doi.org/10.1016/j.amjmed.2019.12.011
    • Veenis, J. F., Brunner-La Rocca, H. P., Linssen, G. C. M., Van Gent, M. W. F., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2020). Treatment Differences in Chronic Heart Failure Patients With Reduced Ejection Fraction According to Blood Pressure. Circulation-Heart Failure, 13(5), Article 006667. https://doi.org/10.1161/circheartfailure.119.006667
    • Stohr, R., Brandenburg, V. M., Heine, G. H., Maeder, M. T., Leibundgut, G., Schuh, A., Jeker, U., Pfisterer, M., Sanders-van Wijk, S., & Brunner-La Rocca, H. P. (2020). Limited role for fibroblast growth factor 23 in assessing prognosis in heart failure patients: data from the TIME-CHF trial. European journal of heart failure, 22(4), 701-709. https://doi.org/10.1002/ejhf.1749
    • Brunner-La Rocca, H. P. (2020). What do we need to better understand the role of biomarkers in heart failure?International Journal of Cardiology, 304, 93-94. https://doi.org/10.1016/j.ijcard.2020.01.018
    • Aizpurua, A. B., Sanders-van Wijk, S., Brunner-La Rocca, H. P., Henkens, M., Heymans, S., Beussink-Nelson, L., Shah, S. J., & van Empel, V. P. M. (2020). Validation of the HFA-PEFF score for the diagnosis of heart failure with preserved ejection fraction. European journal of heart failure, 22(3), 413-421. https://doi.org/10.1002/ejhf.1614
    • Stienen, S., Ferreira, J. P., Kobayashi, M., Preud'homme, G., Dobre, D., Machu, J.-L., Duarte, K., Bresso, E., Devignes, M.-D., Lopez, N., Girerd, N., Aakhus, S., Ambrosio, G., Brunner-La Rocca, H.-P., Fontes-Carvalho, R., Fraser, A. G., Van Heerebeek, L., Heymans, S., De Keulenaer, G., ... Rossignol, P. (2020). Enhanced clinical phenotyping by mechanistic bioprofiling in heart failure with preserved ejection fraction: insights from the MEDIA-DHF study (The Metabolic Road to Diastolic Heart Failure). Biomarkers, 25(2), 201-211. https://doi.org/10.1080/1354750X.2020.1727015
    • Barutaut, M., Fournier, P., Peacock, W. F., Evaristi, M. F., Caubere, C., Turkieh, A., Desmoulin, F., Eurlings, L. W. M., van Wijk, S., Brunner-La Rocca, H.-P., Butler, J., Koukoui, F., Dambrin, C., Mazeres, S., Le Page, S., Delmas, C., Galinier, M., Jung, C., Smih, F., & Rouet, P. (2020). Insulin-like Growth Factor Binding Protein 2 predicts mortality risk in heart failure. International Journal of Cardiology, 300, 245-251. https://doi.org/10.1016/j.ijcard.2019.09.032
    • Verdonschot, J. A. J., Merken, J. J., Brunner-La Rocca, H.-P., Hazebroek, M. R., Eurlings, C. G. M. J., Thijssen, E., Wang, P., Weerts, J., van Empel, V., Schummers, G., Schreckenberg, M., van den Wijngaard, A., Lumens, J., Brunner, H. G., Heymans, S. R. B., Krapels, I. P. C., & Knackstedt, C. (2020). Value of Speckle Tracking-Based Deformation Analysis in Screening Relatives of Patients With Asymptomatic Dilated Cardiomyopathy. JACC-Cardiovascular Imaging, 13(2), 549-558. https://doi.org/10.1016/j.jcmg.2019.02.032
    • Brugts, J. J., Veenis, J. F., Radhoe, S. P., Linssen, G. C. M., van Gent, M., Borleffs, C. J. W., van Ramshorst, J., van Pol, P., Tukkie, R., Spee, R. F., Emans, M. E., Kok, W., van Halm, V. P., Handoko, L., Beeres, S. L. M. A., Post, M. C., Boersma, E., Lenzen, M. J., Manintveld, C., ... de Boer, R. A. (2020). A randomised comparison of the effect of haemodynamic monitoring with CardioMEMS in addition to standard care on quality of life and hospitalisations in patients with chronic heart failure: Design and rationale of the MONITOR HF multicentre randomised clinical trial. Netherlands Heart Journal, 28(1), 16-26. https://doi.org/10.1007/s12471-019-01341-9
    • Ferreira, J. P., Pizard, A., Machu, J.-L., Bresso, E., Brunner-La Rocca, H.-P., Girerd, N., Leroy, C., Gonzalez, A., Diez, J., Heymans, S., Devignes, M.-D., Rossignol, P., Zannad, F., & FIBRO-TARGETS investigators (2020). Plasma protein biomarkers and their association with mutually exclusive cardiovascular phenotypes: the FIBRO-TARGETS case-control analyses. Clinical research in cardiology, 109(1), 22-33. https://doi.org/10.1007/s00392-019-01480-4
    • Leeuwis, A. E., Hooghiemstra, A. M., Bron, E. E., Kuipers, S., Oudeman, E. A., Kalay, T., Brunner-La Rocca, H.-P., Kappelle, L. J., van Oostenbrugge, R. J., Greving, J. P., Niessen, W. J., van Buchem, M. A., van Osch, M. J. P., van Rossum, A. C., Prins, N. D., Biessels, G.-J., Barkhof, F., van der Flier, W. M., & Heart-Brain Connection Consortium (2020). Cerebral blood flow and cognitive functioning in patients with disorders along the heart-brain axis: Cerebral blood flow and the heart-brain axis. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 6(1), Article e12034. https://doi.org/10.1002/trc2.12034
    • van Loon, T., Knackstedt, C., Cornelussen, R., Reesink, K., Brunner-La Rocca, H., Delhaas, T., van Empel, V., & Lumens, J. (2020). Increased myocardial stiffness more than impaired relaxation function limits cardiac performance during exercise in heart failure with preserved ejection fraction: a virtual patient study. European Heart Journal - Digital Health, 1(1), 40-50. https://doi.org/10.1093/ehjdh/ztaa009
  • 2019
    • Barrett, M., Boyne, J., Brandts, J., Brunner-La Rocca, H.-P., De Maesschalck, L., De Wit, K., Dixon, L., Eurlings, C., Fitzsimons, D., Golubnitschaja, O., Hageman, A., Heemskerk, F., Hintzen, A., Helms, T. M., Hill, L., Hoedemakers, T., Marx, N., McDonald, K., Mertens, M., ... Zippel-Schultz, B. (2019). Artificial intelligence supported patient self-care in chronic heart failure: a paradigm shift from reactive to predictive, preventive and personalised care. The EPMA Journal, 10(4), 445-464. https://doi.org/10.1007/s13167-019-00188-9
    • Hooghiemstra, A. M., Leeuwis, A. E., Bertens, A. S., Biessels, G. J., Bots, M. L., Brunner-La Rocca, H.-P., Greving, J. P., Kappelle, L. J., van Oostenbrugge, R. J., van Rossum, A. C., van der Flier, W. M., & Heart-Brain Connection Consortium (2019). Frequent Cognitive Impairment in Patients With Disorders Along the Heart-Brain Axis. Stroke, 50(12), 3369-3375. https://doi.org/10.1161/STROKEAHA.119.026031
    • Baldewijns, K., Brunner-La Rocca, H.-P., de Maesschalck, L., Deville, A., & Boyne, J. (2019). Unravelling heart failure nurses' education: Content comparison of heart failure nurses' education in three European Society of Cardiology states and the Heart Failure Association heart failure curriculum. European Journal of Cardiovascular Nursing, 18(8), 711-719. https://doi.org/10.1177/1474515119863179
    • Smulders, M. W., Kietselaer, B. L. J. H., Wildberger, J. E., Dagnelie, P. C., Brunner-La Rocca, H.-P., Mingels, A. M. A., van Cauteren, Y. J. M., Theunissen, R. A. L. J., Post, M. J., Schalla, S., van Kuijk, S. M. J., Das, M., Kim, R. J., Crijns, H. J. G. M., & Bekkers, S. C. A. M. (2019). Initial Imaging-Guided Strategy Versus Routine Care in Patients With Non-ST-Segment Elevation Myocardial Infarction. Journal of the American College of Cardiology, 74(20), 2466-2477. https://doi.org/10.1016/j.jacc.2019.09.027
    • Gingele, A. J., Ramaekers, B., Brunner-La Rocca, H. P., De Weerd, G., Kragten, J., van Empel, J. M., van der Weg, K., Vrijhoef, H. J. M., Gorgels, A., Cleuren, G., Boyne, J. J. J., & Knackstedt, C. (2019). Effects of tailored telemonitoring on functional status and health-related quality of life in patients with heart failure. Netherlands Heart Journal, 27(11), 565-574. https://doi.org/10.1007/s12471-019-01323-x
    • Aimo, A., Januzzi, J. L., Vergaro, G., Clerico, A., Latini, R., Meessen, J., Anand, I. S., Cohn, J. N., Gravning, J., Ueland, T., Nymo, S. H., Brunner-La Rocca, H.-P., Bayes-Genis, A., Lupon, J., de Boer, R. A., Yoshihisa, A., Takeishi, Y., Egstrup, M., Gustafsson, I., ... Emdin, M. (2019). Revisiting the obesity paradox in heart failure: Per cent body fat as predictor of biomarkers and outcome. European Journal of Preventive Cardiology, 26(16), 1751-1759. Article 2047487319852809. https://doi.org/10.1177/2047487319852809
    • Packer, M., Butler, J., Filippatos, G. S., Jamal, W., Salsali, A., Schnee, J., Kimura, K., Zeller, C., George, J., Brueckmann, M., Anker, S. D., Zannad, F., Perrone, S., Nicholls, S., Janssens, S., Bocchi, E., Giannetti, N., Verma, S., Jian, Z., ... EMPEROR‐Reduced Trial Committees and Investigators (2019). Evaluation of the effect of sodium-glucose co-transporter 2 inhibition with empagliflozin on morbidity and mortality of patients with chronic heart failure and a reduced ejection fraction: rationale for and design of the EMPEROR-Reduced trial. European journal of heart failure, 21(10), 1270-1278. https://doi.org/10.1002/ejhf.1536
    • Veenis, J. F., Brunner-La Rocca, H.-P., Linssen, G. C. M., Geerlings, P. R., Van Gent, M. W. F., Aksoy, I., Oosterom, L., Moons, A. H. M., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2019). Age differences in contemporary treatment of patients with chronic heart failure and reduced ejection fraction. European Journal of Preventive Cardiology, 26(13), 1399-1407. https://doi.org/10.1177/2047487319835042
    • Simonavicius, J., Van-Wijk, S. S., Rickenbacher, P., Maeder, M. T., Pfister, O., Kaufmann, B. A., Pfisterer, M., Celutkiene, J., Puronaite, R., Knackstedt, C., van Empel, V., & Brunner-La Rocca, H.-P. (2019). Prognostic Significance of Longitudinal Clinical Congestion Pattern in Chronic Heart Failure: Insights From TIME-CHF Trial. American Journal of Medicine, 132(9), E679-E692. https://doi.org/10.1016/j.amjmed.2019.04.010
    • Wolters, F. J., Zonneveld, H. I., Licher, S., Cremers, L. G. M., Ikram, M. K., Koudstaal, P. J., Vernooij, M. W., Ikram, M. A., van Buchem, M. A., Biessels, G. J., la Rocca, H.-P. B., De Craen, A. J., van der Flier, W. M., Kappelle, L. J., Mooijaart, S. P., Niessen, W., van Oostenbrugge, R., de Roos, A., van Rossum, A. C., ... Heart Brain Connection (2019). Hemoglobin and anemia in relation to dementia risk and accompanying changes on brain MRI. Neurology, 93(9), E917-E926. https://doi.org/10.1212/WNL.0000000000008003
    • Li, J., She, R. C., Gui, H. S., Zeld, N., Sabbah, H. N., Brunner-LaRocca, H. P., & Lanfear, D. (2019). A Polygenic Response Predictor Indicates Survival Benefit of Beta-Blockade in Heart Failure Patients. Journal of Cardiac Failure, 25(8), S111-S111. https://doi.org/10.1016/j.cardfail.2019.07.317
    • Oudeman, E. A., Greving, J. P., Hooghiemstra, A. M., Brunner-La Rocca, H.-P., Biessels, G. J., Kappelle, L. J., Daemen, M. J., van Buchem, M. A., van der Geest, R. J., van Osch, M. J. P., de Roos, A., van der Flier, W. M., van Rossum, A. C., Ikram, M. A., Koudstaal, P. J., Niessen, W. J., van Oostenbrugge, R., Bots, M. L., & Heart-Brain Connection Consortium (2019). Nonfocal transient neurological attacks are related to cognitive impairment in patients with heart failure. Journal of Neurology, 266(8), 2035-2042. https://doi.org/10.1007/s00415-019-09376-z
    • Janssen, D. J. A., Boyne, J., Currow, D. C., Schols, J. M. G. A., Johnson, M. J., & Brunner-La Rocca, H.-P. (2019). Timely recognition of palliative care needs of patients with advanced chronic heart failure: a pilot study of a Dutch translation of the Needs Assessment Tool: Progressive Disease - Heart Failure (NAT:PD-HF). European Journal of Cardiovascular Nursing, 18(5), 375-388. https://doi.org/10.1177/1474515119831510
    • Gingele, A. J., Brunner-la Rocca, H., Ramaekers, B., Gorgels, A., De Weerd, G., Kragten, J., van Empel, V., Brandenburg, V., Vrijhoef, H., Cleuren, G., Knackstedt, C., & Boyne, J. J. J. (2019). Telemonitoring in patients with heart failure: Is there a long-term effect?Journal of Telemedicine and Telecare, 25(3), 158-166. https://doi.org/10.1177/1357633x17747641
    • Aimo, A., Januzzi, J. L., Vergaro, G., Ripoli, A., Latini, R., Masson, S., Magnoli, M., Anand, I. S., Cohn, J. N., Tavazzi, L., Tognoni, G., Gravning, J., Ueland, T., Nymo, S. H., Brunner-La Rocca, H.-P., Bayes-Genis, A., Lupon, J., de Boer, R. A., Yoshihisa, A., ... Emdin, M. (2019). High-sensitivity troponin T, NT-proBNP and glomerular filtration rate: A multimarker strategy for risk stratification in chronic heart failure. International Journal of Cardiology, 277, 166-172. https://doi.org/10.1016/j.ijcard.2018.10.079
    • Mullens, W., Damman, K., Harjola, V.-P., Mebazaa, A., Brunner-La Rocca, H.-P., Martens, P., Testani, J. M., Tang, W. H. W., Orso, F., Rossignol, P., Metra, M., Filippatos, G., Seferovic, P. M., Ruschitzka, F., & Coats, A. J. (2019). The use of diuretics in heart failure with congestion - a position statement from the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 21(2), 137-155. https://doi.org/10.1002/ejhf.1369
    • Breetveld, N. M., Ghossein-Doha, C., Van Neer, J., Sengers, M. J. J. M., Geerts, L., Van Kuijk, S. M. J., Van Dijk, A. P., Van Der Vlugt, M. J., Heidema, W. M., Brunner-La Rocca, H. P., Scholten, R. R., & Spaanderman, M. E. A. (2019). Decreased Endothelial Function and Increased Subclinical Heart Failure in Women Several Years after Pre-eclampsia. Obstetrical & Gynecological Survey, 74(1), 13-15. https://doi.org/10.1097/01.ogx.0000550509.43053.d7
    • Brunner-La Rocca, H.-P., Linssen, G. C., Smeele, F. J., van Drimmelen, A. A., Schaafsma, H.-J., Westendorp, P. H., Rademaker, P. C., van de Kamp, H. J., Hoes, A. W., Brugts, J. J., & CHECK-HF Investigators (2019). Contemporary Drug Treatment of Chronic Heart Failure With Reduced Ejection Fraction The CHECK-HF Registry. JACC: Heart Failure, 7(1), 13-21. https://doi.org/10.1016/j.jchf.2018.10.010
    • Simonavicius, J., Knackstedt, C., & Brunner-La Rocca, H.-P. (2019). Loop diuretics in chronic heart failure: how to manage congestion?Heart Failure Reviews, 24(1), 17-30. https://doi.org/10.1007/s10741-018-9735-7
    • Eurlings, C. G. M. J., Boyne, J. J., de Boer, R. A., & Brunner-La Rocca, H. P. (2019). Telemedicine in heart failure-more than nice to have?Netherlands Heart Journal, 27(1), 5-15. https://doi.org/10.1007/s12471-018-1202-5
    • Brunner-La Rocca, H., & Sanders - van Wijk, S. (2019). Natriuretic Peptides in Chronic Heart Failure. Cardiac Failure Review, 5(1), 44-49. https://doi.org/10.15420/cfr.2018.26.1
  • 2018
    • Brunner-La Rocca, H.-P., & Sanders-van Wijk, S. (2018). Guiding Heart Failure Therapy After GUIDE-IT Back to the Drawing Board. Journal of the American College of Cardiology, 72(21), 2563-2566. https://doi.org/10.1016/j.jacc.2018.08.2185
    • Emdin, M., Aimo, A., Vergaro, G., Bayes-Genis, A., Lupon, J., Latini, R., Meessen, J., Anand, I. S., Cohn, J. N., Gravning, J., Gullestad, L., Broch, K., Ueland, T., Nymo, S. H., Rocca, H.-P. B.-L., de Boer, R. A., Gaggin, H. K., Ripoli, A., Passino, C., & Januzzi, J. L. (2018). sST2 Predicts Outcome in Chronic Heart Failure Beyond N-proBNP and High-Sensitivity Troponin T. Journal of the American College of Cardiology, 72(19), 2309-2320. https://doi.org/10.1016/j.jacc.2018.08.2165
    • Brandao, S. M., Rezende, P. C., Brunner-La Rocca, H.-P., Ju, Y. T., de Lima, A. C., Takiuti, M. E., Hueb, W., & Bocchi, E. A. (2018). Comparative cost-effectiveness of surgery, angioplasty, or medical therapy in patients with multivessel coronary artery disease: MASS II trial. Cost Effectiveness and Resource Allocation, 16, Article 55. https://doi.org/10.1186/s12962-018-0158-z
    • Steinmann, E., Rocca, H.-P. B.-L., Maeder, M. T., Kaufmann, B. A., Pfisterer, M., & Rickenbacher, P. (2018). Is the clinical presentation of chronic heart failure different in elderly versus younger patients and those with preserved versus reduced ejection fraction?European journal of internal medicine, 57, 61-69. https://doi.org/10.1016/j.ejim.2018.06.005
    • Verdonschot, J. A. J., Hazebroek, M. R., Wang, P., Sanders-van Wijk, S., Merken, J. J., Adriaansen, Y. A., van den Wijngaard, A., Krapels, I. P. C., Brunner-La Rocca, H.-P., Brunner, H. G., & Heymans, S. R. B. (2018). Clinical Phenotype and Genotype Associations With Improvement in Left Ventricular Function in Dilated Cardiomyopathy. Circulation-Heart Failure, 11(11), Article 005220. https://doi.org/10.1161/CIRCHEARTFAILURE.118.005220
    • Bocchi, E. A., da Cruz, F. D. D., Brandao, S. M., Issa, V., Ayub-Ferreira, S. M., la Rocca, H.-P. B., & van Wijk, S. S. (2018). Cost-Effectiveness Benefits of a Disease Management Program: The REMADHE Trial Results. Journal of Cardiac Failure, 24(10), 627-637. https://doi.org/10.1016/j.cardfail.2018.04.008
    • Merken, J., Brunner-La Rocca, H.-P., Weerts, J., Verdonschot, J., Hazebroek, M., Schummers, G., Schreckenberg, M., Lumens, J., Heymans, S., & Knackstedt, C. (2018). Heart Failure With Recovered Ejection Fraction. Journal of the American College of Cardiology, 72(13), 1556-1557. https://doi.org/10.1016/j.jacc.2018.06.070