Stephane Heymans

Professor

Stephane Heymans is Professor of Cardiomyopathies and Head of the Centre for Heart Failure Research, Department of Cardiology, Maastricht University. He obtained his Medical Degree from the KU Leuven (Belgium) in 1995 and went on to get a PhD in Medical Sciences in 2000, studying the role of proteinases in acute myocardial infarction. In 2003, he joined the Department of Cardiology of Maastricht UMC+ as an academic medical specialist and in 2006 he took over the Multidisciplinary Cardiomyopathy Program (Genetics, Immunology, Microbiology and Pathology departments).

In 2008, he established his independent research laboratory at Cardiovascular Research Institute Maastricht. His research interests focus on the molecular mechanisms of heart failure, looking at the interplay between inflammatory cells, fibroblasts and cardiomyocytes. Particular focus is on the role of non-structural matrix proteins, matrix turnover and non-coding RNAs.

Furthermore, he is Professor of 'Inflammation and Matrix Biology in Cardiomyopathies' at the University of Leuven and he is a board member of the ESC Heart Failure Association, ESC Working Group of Myocardial Function, ESC Heart Failure Association Committee on Diastolic Heart Failure and ESC Heart Failure Association Committee on Translational Research.

Website www.hfresearch.eu

Department of Cardiology
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: G3.230
T: +31(0)43 388 43 04

  • 2026
    • Peretto, G., Merlo, M., Ambrosi, A., Bacigalupi, E., Villatore, A., Molinari, L., Anguera, I., Claver, E., Dal Ferro, M., Suwalski, P., Spartalis, M., Verdonschot, J., Ciabatti, M., Martini, N., Zampieri, M., Paldino, A., Valeri, Y., Radesich, C., Lazzeroni, D., ... Sinagra, G. (2026). Major arrhythmias in non-dilated left ventricular cardiomyopathy: a novel prediction score. European Heart Journal, 47(1), 94-106. Article ehaf477. https://doi.org/10.1093/eurheartj/ehaf477
  • 2025
    • Johnson, R., Fletcher, R. A., Peters, S., Ohanian, M., Soka, M., Smolnikov, A., Abihider, K. E., Ackerman, M. J., Ader, F., Akhtar, M. M., Amin, A. S., Ashley, E. A., Atherton, J. J., Austin, R., Baas, A. F., Bagnall, R. D., Ross, S. B., Blouin, J.-L., Brown, E. E., ... Australian Genomics Cardiac Flagship (2025). Titin-related familial dilated cardiomyopathy: factors associated with disease onset. European Heart Journal, 46(48), 5240-5257. https://doi.org/10.1093/eurheartj/ehaf380
    • Stroeks, S. L. V. M., Wang, P., Merlo, M., Muller, S., Paldino, A., Mora-Ayestaran, N., Jason, M., Ferro, M. D., Loca, C. P., Dominguez, F., Gonzalez-Lopez, E., van den Wijngaard, A., Venner, M. F. G. H. M., Sikking, M., Minten, M., Nihant, B., Beelen, N., Graw, S., Medo, K., ... Verdonschot, J. A. J. (2025). Impact of genotype-phenotype associations on prognosis in dilated cardiomyopathy. European journal of heart failure, 27(12), 3205-3218. https://doi.org/10.1002/ejhf.70040
    • Verdonschot, J. A. J., Kaski, J. P., Asselbergs, F. W., Behr, E. R., Charron, P., Dawson, D., Haugaa, K. H., Kuchynka, P., Lopes, L. R., Mazzanti, A., Monserrat, L., Pantazis, A., Prasad, S. K., Schunkert, H., Seferovic, P. M., Sheppard, M. N., Sinagra, G., van Tintelen, J. P., Tome Esteban, M. T., ... Garcia-Pavia, P. (2025). Clinical care of family members of patients with dilated cardiomyopathy: A clinical consensus statement of the Heart Failure Association of the European Society of Cardiology, the European Society of Cardiology Working Group on Myocardial & Pericardial Diseases, and the European Society of Cardiology Council on Cardiovascular Genomics. European Heart Journal, 46(43), 4569-4582. Article ehaf571. https://doi.org/10.1093/eurheartj/ehaf571
    • Lagrange, J., Jahangiri, M., Baudry, G., Monzo, L., Guerci, P., ter Maaten, J. M., Heymans, S., Mercier, N., & Girerd, N. (2025). Updates on the endothelial glycocalyx in heart failure with preserved ejection fraction. American Journal of Physiology-heart and Circulatory Physiology, 329(5), H1316-H1330. https://doi.org/10.1152/ajpheart.00410.2025
    • Venner, M. F. G. H. M., Heymans, A. B. M., Beelen, N. J., Stroeks, S. L. V. M., Faassen, I. M. E., Sikking, M. A., Henkens, M. T. H. M., Van Der Crabben, S. N., Raafs, A. G., Heymans, S. R. B., & Verdonschot, J. A. J. (2025). Predictive value of ambulatory ECG monitoring for malignant arrhythmic events in genetic dilated cardiomyopathy. EP Europace, 27(11), Article euaf279. https://doi.org/10.1093/europace/euaf279
    • Stroeks, S. L. V. M., Merlo, M., Mora-Ayestaran, N., Jason, M., Tayal, U., Wang, P., Cannatà, A., Sikking, M. A., Dal Ferro, M., Peiro, B., Willemars, M., Hellebrekers, D. M. E. I., van Leeuwen, R. E. W., Setti, M., Gonzalez-Lopez, E., Krapels, I. P. C., Pio Loco Detto Gava, C., van den Wijngaard, A., Henkens, M. T. H. M., ... Verdonschot, J. A. J. (2025). Sex Differences in Prognosis of Patients With Genetic Dilated Cardiomyopathy. Circulation-Heart Failure, 18(11), e012592. Article 012592. https://doi.org/10.1161/CIRCHEARTFAILURE.124.012592
    • Gigli, M., Verdonschot, J. A. J., Garcia-Pavia, P., Stolfo, D., Monserrat, L., Prasad, S., Mazzanti, A., Asselbergs, F. W., Bauce, B., Charron, P., Dawson, D., Halliday, B. P., Mestroni, L., Seferovic, P., Tayal, U., Esteban, M. T. T., Van Tintelen, P., Heymans, S., Pantazis, A., ... Sinagra, G. (2025). Future development of arrhythmogenic risk scores in patients with heart failure and inherited dilated cardiomyopathy. A scientific statement of the Heart Failure Association of the ESC. European journal of heart failure, 27(11), 2229-2243. https://doi.org/10.1002/ejhf.70042
    • Setti, M., Iseppi, M., Verdonschot, J. A. J., Rizzi, J. G., Paldino, A., Gava, C. P. L. D., Barbati, G., Dal Ferro, M., Venner, M. F. G. H. M., Raafs, A. G., Gigli, M., Stolfo, D., De Luca, A., De Angelis, G., Capovilla, T. M., Graw, S., Ribichini, F. L., Taylor, M., Mestroni, L., ... Merlo, M. (2025). Integrated role of cardiac magnetic resonance and genetics in predicting left ventricular reverse remodelling in dilated and non-dilated cardiomyopathy. European journal of heart failure, 27(11), 2571-2581. Article 3671. https://doi.org/10.1002/ejhf.3671
    • Sikking, M., Wiethoff, I., Henkens, M., Evers, S., Stroeks, S., Venner, M., Weerts, J., Brunner-la Rocca, H.-P., Knackstedt, C., van Empel, V., Michels, M., Heymans, S., Hiligsmann, M., & Verdonschot, J. (2025). High societal costs and reduced health-related quality of life in inflammatory and systemic immune disease-associated dilated cardiomyopathies. Quality of Life Research, 34(10), 2901-2910. https://doi.org/10.1007/s11136-025-04027-5
    • Fragasso, G., Stolfo, D., Anker, M. S., Bayes-Genis, A., Chioncel, O., Heymans, S., Jhund, P. S., Lewis, B. S., Lopaschuk, G. D., Lund, L. H., Gonzalez, A., Pagnesi, M., Schiattarella, G. G., Tocchetti, C. G., van Der Meer, P., Von Linthout, S., Wassmann, S., Westenbrink, B. D., Metra, M., ... Savarese, G. (2025). The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC. European journal of heart failure, 27(9), 1700-1719. https://doi.org/10.1002/ejhf.3703
    • Weerts, J., Schroen, B. L. M., Barandiaran Aizpurua, A., Berendschot, T. T. J. M., Brandts, L., Webers, C. A. B., Simons, S. O., Meex, S. J. R., Henry, R., van der Kallen, C. J. H., Brunner-La Rocca, H.-P., Knackstedt, C., Heymans, S. R. B., de Boer, R. A., van Empel, V. P. M., & Houben, A. J. H. M. (2025). Microvascular dysfunction across organs in heart failure with preserved ejection fraction: the PROSE-HFpEF case-control study. Cardiovascular Diabetology, 24(1), Article 310. https://doi.org/10.1186/s12933-025-02850-1
    • Venner, M. F. G. H. M., Gevers, T. J. G., Ploum, F., Habets, J., Raafs, A. G., Weerts, J., Heymans, S. R. B., van der Leij, C., de Haan, M. W., Verdonschot, J. A. J., Kramer, M., & Knackstedt, C. (2025). Diastolic dysfunction as predictive parameter for the development of post-TIPS cardiac decompensation. International Journal of Cardiology, 431, Article 133226. https://doi.org/10.1016/j.ijcard.2025.133226
    • Wong, L. Y., Torfs, T., Vanherle, S. J. V., Janssen, J., Claes, G. R. F., Stroeks, S. L. V. M., Willemars, M. M. A., Schianchi, F., Kapsokalyvas, D., Weltjens, E., Swinnen, A., Strzelecka, A., Krapels, I. P. C., Heymans, S. R. B., Glatz, J., van den Wijngaard, A., Brunner, H. G., Broers, J., Luiken, J. F. P., ... Nabben, M. (2025). Clinical and metabolic consequences of a historic pathogenic lamin A/C founder variant. Scientific Reports, 15(1), Article 23842. https://doi.org/10.1038/s41598-025-08495-0
    • Kerneis, M., Ammirati, E., Delmas, C., Heggermont, W., Heymans, S., Lenz, M., Madonna, R., Morosin, M., Schaubroeck, H., Sionis, A., Tsaban, G., Uzokov, J., Vardanyan, K., Vandenbriele, C., & Roubille, F. (2025). Clinical Management of Acute myocarditis in daily practice: an expert practical view. European Heart Journal: Acute Cardiovascular Care, 14(7), 420-431. https://doi.org/10.1093/ehjacc/zuaf057
    • Raman, J., Simmonds, S. J., Caluwé, E., van Leeuwen, R., Walschap, C., Stroobants, M., Cöl, Ü., Vandervoort, P., Heymans, S., & Jones, E. A. V. (2025). Ccr2+ Monocyte-Derived Macrophages Drive Cardiac Hypertrophy In Early Hfpef. American Journal of Physiology-heart and Circulatory Physiology, 329(1), H109-H123. https://doi.org/10.1152/ajpheart.00022.2025
    • Ghigo, A., Ameri, P., Asnani, A., Bertero, E., de Boer, R. A., Farmakis, D., González, A., Heymans, S., Ibáñez, B., López-Fernández, T., Lyon, A. R., Pollesello, P., Rakisheva, A., Stellos, K., Streckfuss-Bömeke, K., Tocchetti, C. G., Thum, T., van der Meer, P., Van Rooij, E., ... Van Linthout, S. (2025). Update on preclinical models of cancer therapy-related cardiac dysfunction: Challenges and perspectives. A scientific statement of the Heart Failure Association (HFA) of the ESC, the ESC Council of Cardio-Oncology, and the ESC Working Group on Cellular Biology of the Heart. European journal of heart failure, 27(6), 1028-1046. https://doi.org/10.1002/ejhf.3636
    • Groeneweg, J. A., van Dalen, B. M., Cox, M. P. G. J., Heymans, S., Braam, R. L., Michels, M., & Asselbergs, F. W. (2025). 2023 European Society of Cardiology guidelines on the management of cardiomyopathies: Statement of endorsement by the NVVC. Netherlands Heart Journal, 33(5), 148-156. https://doi.org/10.1007/s12471-025-01955-2
    • Karakasis, P., Lefkou, E., Pamporis, K., Heymans, S., Filippatos, G., & Fragakis, N. (2025). Reply to the letter regarding the article 'Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta-analysis'. European journal of heart failure, 27(5), 933-934. https://doi.org/10.1002/ejhf.3660
    • Gigli, M., Stolfo, D., Barbati, G., Graw, S., Chen, S. N., Merlo, M., Medo, K., Gregorio, C., Dal Ferro, M., Paldino, A., Perotto, M., Peter van Tintelen, J., Te Riele, A. S. J. M., Baas, A. F., Wilde, A. M., Amin, A. S., Houweling, A. C., Elliott, P., Cannie, D., ... Filamin C Registry Consortium (2025). Arrhythmic Risk Stratification of Carriers of Filamin C Truncating Variants. JAMA Cardiology, 10(4), 359-369. https://doi.org/10.1001/jamacardio.2024.5543
    • Karakasis, P., Lefkou, E., Pamporis, K., Farmakis, D., Patoulias, D., Antoniadis, A. P., Heymans, S., Filippatos, G., & Fragakis, N. (2025). Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta-analysis. European journal of heart failure. Advance online publication. https://doi.org/10.1002/ejhf.3637
    • Monzo, L., Kobayashi, M., Ferreira, J. P., Lamiral, Z., Delles, C., Clark, A. L., Edelmann, F., González, A., Heymans, S., Pellicori, P., Petutschnigg, J., Verdonschot, J. A. J., Rossignol, P., Cleland, J. G. F., Zannad, F., Girerd, N., & HOMAGE “Heart Omics in AGEing” Trial Committees and Investigators (2025). Echocardiographic and biomarker characteristics in diabetes, coronary artery disease or both: insights from HOMAGE trial. Cardiovascular Diabetology, 24(1), Article 111. https://doi.org/10.1186/s12933-025-02609-8
    • Timmer, L. T., den Hertog, E., Versteeg, D., Post, H., Verdonschot, J. A. J., Monshouwer-Kloots, J., Kyriakopoulou, E., Perini, I., Koopmans, T., van der Kraak, P., Zentilin, L., Heymans, S. R. B., Vink, A., Giacca, M., Heck, A. J. R., & van Rooij, E. (2025). Cardiomyocyte SORBS2 expression increases in heart failure and regulates integrin interactions and extracellular matrix composition. Cardiovascular Research, 121(4), 585-600. Article cvaf021. https://doi.org/10.1093/cvr/cvaf021
    • Grootaert, M. O. J., Pasut, A., Raman, J., Simmonds, S. J., Callewaert, B., Col, Ü., Dewerchin, M., Carmeliet, P., Heymans, S., & Jones, E. A. V. (2025). Mural cell dysfunction contributes to diastolic heart failure by promoting endothelial dysfunction and vessel remodelling. Cardiovascular Diabetology, 24(1), Article 62. https://doi.org/10.1186/s12933-025-02623-w
    • Stroeks, S. L. V. M., Henkens, M. T. H. M., Dominguez, F., Merlo, M., Hellebrekers, D. M. E. I., Gonzalez-Lopez, E., Dal Ferro, M., Ochoa, J. P., Venturelli, F., Claes, G. R. F., Venner, M. F. G. H. M., Krapels, I. P. C., Vanhoutte, E. K., van Paassen, P., van den Wijngaard, A., Sikking, M. A., van Leeuwen, R., Abdul Hamid, M., Li, X., ... Verdonschot, J. A. J. (2025). Genetic Landscape of Patients With Dilated Cardiomyopathy and a Systemic Immune-Mediated Disease. JACC: Heart Failure, 13(1), 133-145. https://doi.org/10.1016/j.jchf.2024.08.011
    • Van Linthout, S., Stellos, K., Giacca, M., Bertero, E., Cannata, A., Carrier, L., Garcia-Pavia, P., Ghigo, A., Gonzalez, A., Haugaa, K. H., Imazio, M., Lopes, L. R., Most, P., Pollesello, P., Schunkert, H., Streckfuss-Boemeke, K., Thum, T., Tocchetti, C. G., Tschoepe, C., ... Heymans, S. (2025). State of the art and perspectives of gene therapy in heart failure. A scientific statement of the Heart Failure Association of the ESC, the ESC Council on Cardiovascular Genomics and the ESC Working Group on Myocardial & Pericardial Diseases. European journal of heart failure, 27(1), 5-25. https://doi.org/10.1002/ejhf.3516
  • 2024
    • Sikking, M. A., Harding, D., Henkens, M. T. H. M., Stroeks, S. L. V. M., Venner, M. F. G. H. M., Nihant, B., van Leeuwen, R. E. W., Fanti, S., Li, X., van Paassen, P., Knackstedt, C., Brunner-la Rocca, H.-P., van Empel, V. P. M., Verdonschot, J. A. J., Marelli-Berg, F. M., & Heymans, S. R. B. (2024). Cytotoxic T-Cells Drive Outcome in Inflammatory Dilated Cardiomyopathy. Circulation Research, 135(12), 1193-1195. https://doi.org/10.1161/CIRCRESAHA.124.325183
    • Verdonschot, J. A. J., Fuster, J. J., Walsh, K., & Heymans, S. R. B. (2024). The emerging role of clonal haematopoiesis in the pathogenesis of dilated cardiomyopathy. European Heart Journal, 45(45), 4797-4807. Article ehae682. https://doi.org/10.1093/eurheartj/ehae682
    • Wei, F.-F., Mariottoni, B., An, D.-W., Pellicori, P., Yu, Y.-L., Verdonschot, J. A. J., Liu, C., Ahmed, F. Z., Petutschnigg, J., Rossignol, P., Heymans, S., Cuthbert, J., Girerd, N., Li, Y., Clark, A. L., Nawrot, T. S., Ferreira, J. P., Zannad, F., Cleland, J. G. F., ... HOMAGE investigators (2024). Heart rate reactivity, recovery, and endurance of the incremental shuttle walk test in patients prone to heart failure. Esc heart failure, 11(6), 4116-4126. https://doi.org/10.1002/ehf2.15000
    • Wei, F.-F., Pellicori, P., Ferreira, J. P., González, A., Mariottoni, B., An, D.-W., Verdonschot, J. A. J., Liu, C., Ahmed, F. Z., Petutschnigg, J., Rossignol, P., Heymans, S., Cuthbert, J., Girerd, N., Clark, A. L., Li, Y., Nawrot, T. S., Díez, J., Zannad, F., ... HOMAGE investigators (2024). Effects of spironolactone on exercise blood pressure in patients at increased risk of developing heart failure: report from the HOMAGE trial. Hypertension Research, 47(11), 3225-3236. https://doi.org/10.1038/s41440-024-01843-z
    • Verdonschot, J. A. J., Heymans, S. R. B., & Van Linthout, S. (2024). The next era of gene-specific clinical care in patients with dilated cardiomyopathy. European journal of heart failure, 26(10), 2169-2172. https://doi.org/10.1002/ejhf.3446
    • Yu, Y.-L., Siwy, J., An, D.-W., González, A., Hansen, T., Latosinska, A., Pellicori, P., Ravassa, S., Mariottoni, B., Verdonschot, J. A., Ahmed, F., Petutschnigg, J., Rossignol, P., Heymans, S., Cuthbert, J. J., Girerd, N., Clark, A. L., Verhamme, P., Nawrot, T. S., ... HOMAGE investigators (2024). Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial. Heart, 110(19), 1180-1187. Article heartjnl-2023-323796. https://doi.org/10.1136/heartjnl-2023-323796
    • Beijnink, C. W. H., Raafs, A. G., Vos, J. L., Verdonschot, J. A. J., Sikking, M. A., Rodwell, L., Heymans, S. R. B., & Nijveldt, R. (2024). Papillary Muscle Delayed Hyperenhancement: Prevalence and Clinical Implications in a Large Population With Dilated Cardiomyopathy. JACC: Advances, 3(8), Article 101103. https://doi.org/10.1016/j.jacadv.2024.101103
    • Machiraju, P., Srinivas, R., Kannan, R., George, R., Heymans, S., Mukhopadhyay, R., & Ghosh, A. (2024). Paired Transcriptomic Analyses of Atheromatous and Control Vessels Reveal Novel Autophagy and Immunoregulatory Genes in Peripheral Artery Disease. Cells, 13(15), Article 1269. https://doi.org/10.3390/cells13151269
    • Heymans, S., Van Linthout, S., Kraus, S. M., Cooper, L. T., & Ntusi, N. A. B. (2024). Clinical Characteristics and Mechanisms of Acute Myocarditis. Circulation Research, 135(2), 397-411. https://doi.org/10.1161/CIRCRESAHA.124.324674
    • Nihant, B., Verdonschot, J., Heymans, S., Breuer, M., & Adriaens, M. (2024). Computational models of cardiac metabolism reveal distinct metabolic phenotypes in dilated cardiomyopathy patients. European journal of heart failure, 26, 640-641.
    • Falcao-Pires, I., Ferreira, A. F., Trindade, F., Bertrand, L., Ciccarelli, M., Visco, V., Dawson, D., Hamdani, N., Van Laake, L. W., Lezoualc'h, F., Linke, W. A., Lunde, I. G., Rainer, P. P., Abdellatif, M., van der Velden, J., Cosentino, N., Paldino, A., Pompilio, G., Zacchigna, S., ... Tocchetti, C. G. (2024). Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function. European journal of heart failure, 26(7), 1454-1479. https://doi.org/10.1002/ejhf.3264
    • Wiethoff, I., Sikking, M., Evers, S., Gabrio, A., Henkens, M., Michels, M., Verdonschot, J., Heymans, S., & Hiligsmann, M. (2024). Quality of life and societal costs in patients with dilated cardiomyopathy. European heart journal - Quality of care & clinical outcomes, 10(4), 334-344. Article qcad056. https://doi.org/10.1093/ehjqcco/qcad056
    • Sikking, M. A., Stroeks, S. L. V. M., Henkens, M. T. H. M., Raafs, A. G., Cossins, B., van Deuren, R. C., Steehouwer, M., Riksen, N. P., van den Wijngaard, A., Brunner, H. G., Hoischen, A., Verdonschot, J. A. J., & Heymans, S. R. B. (2024). Clonal Hematopoiesis has Prognostic Value in Dilated Cardiomyopathy independent of Age and Clone Size. JACC: Heart Failure, 12(5), 905-914. https://doi.org/10.1016/j.jchf.2023.06.037
    • Kobayashi, M., Ferreira, J. P., Kevin, D., Bresso, E., Huttin, O., Bozec, E., Brunner La Rocca, H.-P., Delles, C., Clark, A. L., Edelmann, F., González, A., Heymans, S., Pellicori, P., Petutschnigg, J., Verdonschot, J. A. J., Rossignol, P., Cleland, J. G. F., Zannad, F., Girerd, N., & HOMAGE Trial Committees and Investigators (2024). Proteomic profiles of left atrial volume and its influence on response to spironolactone: Findings from the HOMAGE trial and STANISLAS cohort. European journal of heart failure, 26(5), 1231-1241. https://doi.org/10.1002/ejhf.3202
    • Weerts, J., Raafs, A. G., Sandhoefner, B., van der Heide, F. C. T., Mourmans, S. G. J., Wolff, N., Finger, R. P., Falahat, P., Wintergerst, M. W. M., van Empel, V. P. M., & Heymans, S. R. B. (2024). Retinal Vascular Changes in Heart Failure with Preserved Ejection Fraction Using Optical Coherence Tomography Angiography. Journal of Clinical Medicine, 13(7), Article 1892. https://doi.org/10.3390/jcm13071892
    • Verdonschot, J. A. J., Hellebrekers, D. M. E. I., van Empel, V. P. M., Heijligers, M., de Munnik, S., Coonen, E., Dreesen, J. C. M. F., van den Wijngaard, A., Brunner, H. G., Zamani Esteki, M., Heymans, S. R. B., de Die-Smulders, C. E. M., & Paulussen, A. D. C. (2024). Clinical Guideline for Preimplantation Genetic Testing in Inherited Cardiac Diseases. Circulation: Genomic and Precision Medicine, 17(2), Article E004416. https://doi.org/10.1161/CIRCGEN.123.004416
    • Verdonschot, J. A. J., & Heymans, S. R. B. (2024). Dilated cardiomyopathy: second hits knock-down the heart. European Heart Journal, 45(7), 500-501. https://doi.org/10.1093/eurheartj/ehad778
    • Santos-Ferreira, D., Diaz, S. O., Ferreira, J. P., Girerd, N., Pellicori, P., Mariottoni, B., Cosmi, F., Hazebroek, M., Verdonschot, J. A. J., Cuthbert, J., Petutschnigg, J., Heymans, S., Staessen, J. A., Pieske, B., Edelmann, F., Clark, A. L., Rossignol, P., Fontes-Carvalho, R., Cleland, J. G. F., & Zannad, F. (2024). Phenotyping patients with ischaemic heart disease at risk of developing heart failure: an analysis of the HOMAGE trial. Esc heart failure, 11(1), 209-218. https://doi.org/10.1002/ehf2.14465
    • Shanbagh, S., Gadde, S. G., Shetty, R., Heymans, S., Abilash, V. G., Chaurasia, S. S., & Ghosh, A. (2024). Hyperglycemia-induced miR182-5p drives glycolytic and angiogenic response in Proliferative Diabetic Retinopathy and RPE cells via depleting FoxO1. Experimental Eye Research, 238, Article 109713. https://doi.org/10.1016/j.exer.2023.109713
    • McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Boehm, M., Burri, H., Butler, J., Celutkiene, J., Chioncel, O., Cleland, J. G. F., Crespo-Leiro, M. G., Farmakis, D., Gilard, M., Heymans, S., Hoes, A. W., Jaarsma, T., Jankowska, E. A., Lainscak, M., ... ESC Scientific Document Group (2024). 2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European journal of heart failure, 26(1), 5-17. https://doi.org/10.1002/ejhf.3024
    • Simmonds, S. J., Grootaert, M. O. J., Cuijpers, I., Carai, P., Geuens, N., Herwig, M., Baatsen, P., Hamdani, N., Luttun, A., Heymans, S., & Jones, E. A. V. (2024). Pericyte loss initiates microvascular dysfunction in the development of diastolic dysfunction. European heart journal open, 4(1), Article oead129. https://doi.org/10.1093/ehjopen/oead129
  • 2023
    • Ciccarelli, M., Pires, I. F., Bauersachs, J., Bertrand, L., Beauloye, C., Dawson, D., Hamdani, N., Hilfiker-Kleiner, D., van Laake, L. W., Lezoualc'h, F., Linke, W. A., Lunde, I. G., Rainer, P. P., Rispoli, A., Visco, V., Carrizzo, A., Ferro, M. D., Stolfo, D., van der Velden, J., ... Tocchetti, C. G. (2023). Acute heart failure: mechanisms and pre-clinical models-a Scientific Statement of the ESC Working Group on Myocardial Function. Cardiovascular Research, 119(14), 2390-2404. Article cvad088. https://doi.org/10.1093/cvr/cvad088
    • Babu, V. S., Mallipatna, A., Dudeja, G., Shetty, R., Nair, A. P., Tun, S. B. B., Ho, C. E. H., Chaurasia, S. S., Bhattacharya, S. S., Verma, N. K., Lakshminarayanan, R., Guha, N., Heymans, S., Barathi, V. A., & Ghosh, A. (2023). Depleted hexokinase1 and lack of AMPKα activation favor OXPHOS-dependent energetics in retinoblastoma tumors. Translational Research, 261(1), 41-56. https://doi.org/10.1016/j.trsl.2023.07.001
    • Sikking, M. A., Stroeks, S. L. V. M., Marelli-Berg, F., Heymans, S. R. B., Ludewig, B., & Verdonschot, J. A. J. (2023). Immunomodulation of Myocardial Fibrosis. JACC: Basic to Translational Science, 8(11), 1477-1488. https://doi.org/10.1016/j.jacbts.2023.03.015