• 2012
    • Angin, Y., Steinbusch, L. K. M., Simons, P. J., Greulich, S., Hoebers, N. T. H., Douma, K., van Zandvoort, M. A. M. J., Coumans, W. A., Wijnen, W., Diamant, M., Ouwens, D. M., Glatz, J. F. C., & Luiken, J. J. F. P. (2012). CD36 inhibition prevents lipid accumulation and contractile dysfunction in rat cardiomyocytes. Biochemical Journal, 448, 43-53. https://doi.org/10.1042/BJ20120060
    • Postma, A. A., Hofman, P. A. M., Stadler, A. A. R., van Oostenbrugge, R. J., Tijssen, M. P. M., & Wildberger, J. E. (2012). Dual-Energy CT of the Brain and Intracranial Vessels. American Journal of Roentgenology, 199(5), S26-S33. https://doi.org/10.2214/AJR.12.9115
    • Collins, J. J. P., Kuypers, E., Nitsos, I., Pillow, J. J., Polglase, G. R., Kemp, M. W., Newnham, J. P., Cleutjens, J. P., Frints, S. G. M., Kallapur, S. G., Jobe, A. H., & Kramer, B. W. (2012). LPS-induced chorioamnionitis and antenatal corticosteroids modulate Shh signaling in the ovine fetal lung. American Journal of Physiology-Lung Cellular and Molecular Physiology, 303(9), L778-L787. https://doi.org/10.1152/ajplung.00280.2011
    • Nazari-Jahantigh, M., Wei, Y., Noels, H., Akhtar, S., Zhou, Z., Koenen, R. R., Heyll, K., Gremse, F., Kiessling, F., Grommes, J., Weber, C., & Schober, A. (2012). MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. Journal of Clinical Investigation, 122(11), 4190-4202. https://doi.org/10.1172/JCI61716
    • Fokong, S., Theek, B., Wu, Z., Koczera, P., Appold, L., Jorge, S., Resch-Genger, U., van Zandvoort, M., Storm, G., Kiessling, F., & Lammers, T. (2012). Image-guided, targeted and triggered drug delivery to tumors using polymer-based microbubbles. Journal of Controlled Release, 163(1), 75-81. https://doi.org/10.1016/j.jconrel.2012.05.007
    • van der Vorst, E. P. C., Keijbeck, A. A., de Winther, M. P. J., & Donners, M. M. P. C. (2012). A disintegrin and metalloproteases: Molecular scissors in angiogenesis, inflammation and atherosclerosis. Atherosclerosis, 224(2), 302-308. https://doi.org/10.1016/j.atherosclerosis.2012.04.023
    • Foulquier, S., Steckelings, U. M., & Unger, T. (2012). Impact of the AT(2) Receptor Agonist C21 on Blood Pressure and Beyond. Current Hypertension Reports, 14(5), 403-409. https://doi.org/10.1007/s11906-012-0291-6
    • Schuh, A., Kroh, A., Konschalla, S., Liehn, E. A., Sobota, R. M., Al Biessen, E., Bot, I., Taha, S. T., Schober, A., Marx, N., Weber, C., & Sasse, A. (2012). Myocardial regeneration by transplantation of modified endothelial progenitor cells expressing SDF-1 in a rat model. Journal of Cellular and Molecular Medicine, 16(10), 2311-2320. https://doi.org/10.1111/j.1582-4934.2012.01539.x
    • King, J. D. J., Lee, J., Riemen, C. E., Neumann, D., Xiong, S., Foskett, J. K., Mehta, A., Muimo, R., & Hallows, K. R. (2012). Role of Binding and Nucleoside Diphosphate Kinase A in the Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator by AMP-activated Protein Kinase. Journal of Biological Chemistry, 287(40), 33389-33400. https://doi.org/10.1074/jbc.M112.396036
    • Viswanathan, K., Bot, I., Liu, L., Dai, E., Turner, P. C., Togonu-Bickersteth, B., Richardson, J., Davids, J. A., Williams, J. M., Bartee, M. Y., Chen, H., van Berkel, T. J. C., Biessen, E. A. L., Moyer, R. W., & Lucas, A. R. (2012). Viral Cross-Class Serpin Inhibits Vascular Inflammation and T Lymphocyte Fratricide; A Study in Rodent Models In Vivo and Human Cell Lines In Vitro. PLOS ONE, 7(9), Article e44694. https://doi.org/10.1371/journal.pone.0044694
    • de Jager, S. C. A., Bongaerts, B. W. C., Weber, M., Kraaijeveld, A. O., Rousch, M., Dimmeler, S., van Dieijen-Visser, M. P., Cleutjens, K. B. J. M., Nelemans, P. J., van Berkel, T. J. C., & Biessen, E. A. L. (2012). Chemokines CCL3/MIP 1 alpha, CCL5/RANTES and CCL18/PARC are Independent Risk Predictors of Short-Term Mortality in Patients with Acute Coronary Syndromes. PLOS ONE, 7(9), Article 45804. https://doi.org/10.1371/journal.pone.0045804
    • Smedbakken, L. M., Halvorsen, B., Daissormont, I., Ranheim, T., Michelsen, A. E., Skjelland, M., Sagen, E. L., Folkersen, L., Krohg-Sorensen, K., Russell, D., Holm, S., Ueland, T., Fevang, B., Hedin, U., Yndestad, A., Gullestad, L., Hansson, G. K., Biessen, E. A., & Aukrust, P. (2012). Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization. Atherosclerosis, 224(1), 266-273. https://doi.org/10.1016/j.atherosclerosis.2012.06.071
    • Schurgers, L. J., Joosen, I. A., Laufer, E. M., Chatrou, M. L. L., Herfs, M., Winkens, M. H. M., Westenfeld, R., Veulemans, V., Krueger, T., Shanahan, C. M., Jahnen-Dechent, W., Biessen, E., Narula, J., Vermeer, C., Hofstra, L., & Reutelingsperger, C. P. (2012). Vitamin K-Antagonists Accelerate Atherosclerotic Calcification and Induce a Vulnerable Plaque Phenotype. PLOS ONE, 7(8), Article e43229. https://doi.org/10.1371/journal.pone.0043229
    • Tokarska-Schlattner, M., Epand, R. F., Meiler, F., Zandomeneghi, G., Neumann, D., Widmer, H. R., Meier, B. H., Epand, R. M., Saks, V., Wallimann, T., & Schlattner, U. (2012). Phosphocreatine Interacts with Phospholipids, Affects Membrane Properties and Exerts Membrane-Protective Effects. PLOS ONE, 7(8), Article e43178. https://doi.org/10.1371/journal.pone.0043178
    • Loos, C. M. J., Staals, J., Wardlaw, J. M., & van Oostenbrugge, R. J. (2012). Cavitation of Deep Lacunar Infarcts in Patients With First-Ever Lacunar Stroke A 2-Year Follow-Up Study With MR. Stroke, 43(8), 2245-U450. https://doi.org/10.1161/STROKEAHA.112.660076
    • den Dekker, W. K., Tempel, D., Bot, I., Biessen, E. A., Joosten, L. A., Netea, M. G., van der Meer, J. W. M., Cheng, C., & Duckers, H. J. (2012). Mast Cells Induce Vascular Smooth Muscle Cell Apoptosis via a Toll-Like Receptor 4 Activation Pathway. Arteriosclerosis Thrombosis and Vascular Biology, 32(8), 1960-1969. https://doi.org/10.1161/ATVBAHA.112.250605
    • Rouhl, R. P. W., Damoiseaux, J. G. M. C., Lodder, J., Theunissen, R. O. M. F. I. H., Knottnerus, I. L. H., Staals, J., Henskens, L. H. G., Kroon, A. A., de Leeuw, P. W., Tervaert, J. W. C., & van Oostenbrugge, R. J. (2012). Vascular inflammation in cerebral small vessel disease. Neurobiology of Aging, 33(8), 1800-1806. https://doi.org/10.1016/j.neurobiolaging.2011.04.008
    • Kwee, R. M., Truijman, M. T., van Oostenbrugge, R. J., Mess, W. H., Prins, M. H., Franke, CL., Korten, A. G., Wildberger, J. E., & Kooi, M. E. (2012). Longitudinal MRI study on the natural history of carotid artery plaques in symptomatic patients. PLOS ONE, 7(7), Article 42472. https://doi.org/10.1371/journal.pone.0042472
    • Hermans, M. C. E., Faber, C. G., Bekkers, S. C. A. M., de Die-Smulders, C. E. M., Gerrits, M. M., Merkies, I. S. J., Snoep, G., Pinto, Y. M., & Schalla, S. (2012). Structural and functional cardiac changes in myotonic dystrophy type 1: a cardiovascular magnetic resonance study. Journal of Cardiovascular Magnetic Resonance, 14, 46. https://doi.org/10.1186/1532-429X-14-48
    • Mees, S. M. D., Algra, A., Vandertop, W. P., van Kooten, F., Kuijsten, H. A. J. M., Boiten, J., van Oostenbrugge, R. J., Salman, R. A.-S., Lavados, P. M., Rinkel, G. J. E., & van den Bergh, W. M. (2012). Magnesium for aneurysmal subarachnoid haemorrhage (MASH-2): a randomised placebo-controlled trial. Lancet, 380(9836), 44-49. https://doi.org/10.1016/S0140-6736(12)60724-7
    • Chen, L., Wang, J., Zhang, Y.-Y., Yan, S. F., Neumann, D., Schlattner, U., Wang, Z.-X., & Wu, J.-W. (2012). AMP-activated protein kinase undergoes nucleotide-dependent conformational changes. Nature Structural and Molecular Biology, 19(7), 716–718. https://doi.org/10.1038/nsmb.2319
    • Doering, Y., Soehnlein, O., Drechsler, M., Shagdarsuren, E., Chaudhari, S. M., Meiler, S., Hartwig, H., Hristov, M., Koenen, R. R., Hieronymus, T., Zenke, M., Weber, C., & Zernecke, A. (2012). Hematopoietic Interferon Regulatory Factor 8-Deficiency Accelerates Atherosclerosis in Mice. Arteriosclerosis Thrombosis and Vascular Biology, 32(7), 1613-1623. https://doi.org/10.1161/ATVBAHA.111.236539
    • Goossens, G. H., Moors, C. C., van der Zijl, N. J., Venteclef, N., Alili, R., Jocken, J. W., Essers, Y., Cleutjens, J. P. M., Clement, K., Diamant, M., & Blaak, E. E. (2012). Valsartan Improves Adipose Tissue Function in Humans with Impaired Glucose Metabolism: A Randomized Placebo-Controlled Double-Blind Trial. PLOS ONE, 7(6), Article 39930. https://doi.org/10.1371/journal.pone.0039930
    • Cheng, C., Haasdijk, R., Tempel, D., van de Kamp, E. H. M., Herpers, R., Bos, F., Den Dekker, W. K., Blonden, L. A. J., de Jong, R., Burgisser, P. E., Chrifi, I., Biessen, E. A. L., Dimmeler, S., Schulte-Merker, S., & Duckers, H. J. (2012). Endothelial Cell-Specific FGD5 Involvement in Vascular Pruning Defines Neovessel Fate in Mice. Circulation, 125(25), 3142–3159. https://doi.org/10.1161/CIRCULATIONAHA.111.064030
    • Grommes, J., Vijayan, S., Drechsler, M., Hartwig, H., Moergelin, M., Dembinski, R., Jacobs, M., Koeppel, T. A., Binneboesel, M., Weber, C., & Soehnlein, O. (2012). Simvastatin Reduces Endotoxin-Induced Acute Lung Injury by Decreasing Neutrophil Recruitment and Radical Formation. PLOS ONE, 7(6), Article e38917. https://doi.org/10.1371/journal.pone.0038917
    • Stadler, N., Heeneman, S., Voo, S., Stanley, N., Giles, G. I., Gang, B. P., Croft, K. D., Mori, T. A., Vacata, V., Daemen, M. J. A. P., Waltenberger, J., & Davies, M. J. (2012). Reduced metal ion concentrations in atherosclerotic plaques from subjects with Type 2 diabetes mellitus. Atherosclerosis, 222(2), 512-518. https://doi.org/10.1016/j.atherosclerosis.2012.03.015
    • Dirks, M., Niessen, L. W., van Wijngaarden, J., Koudstaal, P. J., Franke, C. L., van Oostenbrugge, R. J., & Dippel, D. W. J. (2012). The effectiveness of thrombolysis with intravenous alteplase for acute ischemic stroke in daily practice. International journal of stroke, 7(4), 289-292. https://doi.org/10.1111/j.1747-4949.2011.00709.x
    • Versluis, B., Dremmen, M. H. G., Nelemans, P. J., Wildberger, J. E., Schurink, G.-W., Leiner, T., & Backes, W. H. (2012). Dynamic Contrast-Enhanced MRI Assessment of Hyperemic Fractional Microvascular Blood Plasma Volume in Peripheral Arterial Disease: Initial Findings. PLOS ONE, 7(5), Article e37756. https://doi.org/10.1371/journal.pone.0037756
    • Jaarsma, C., Leiner, T., Bekkers, S. C., Crijns, H. J., Wildberger, J. E., Nagel, E., Nelemans, P. J., & Schalla, S. (2012). Diagnostic Performance of Noninvasive Myocardial Perfusion Imaging Using Single-Photon Emission Computed Tomography, Cardiac Magnetic Resonance, and Positron Emission Tomography Imaging for the Detection of Obstructive Coronary Artery Disease A Meta-Analysis. Journal of the American College of Cardiology, 59(19), 1719-1728. https://doi.org/10.1016/j.jacc.2011.12.040
    • Postea, O., Vasina, E. M., Cauwenberghs, S., Projahn, D., Liehn, E. A., Lievens, D., Theelen, W., Kramp, B. K., Butoi, E. D., Soehnlein, O., Heemskerk, J. W. M., Ludwig, A., Weber, C., & Koenen, R. R. (2012). Contribution of Platelet CX(3)CR1 to Platelet-Monocyte Complex Formation and Vascular Recruitment During Hyperlipidemia. Arteriosclerosis Thrombosis and Vascular Biology, 32(5), 1186-1193. https://doi.org/10.1161/ATVBAHA.111.243485
    • Greiner, A., Mess, W. H., Schmidli, J., Debus, E. S., Grommes, J., Dick, F., & Jacobs, M. J. (2012). Cyber medicine enables remote neuromonitoring during aortic surgery. Journal of Vascular Surgery, 55(5), 1227-1233. https://doi.org/10.1016/j.jvs.2011.11.121
    • Rahimi, N., Molin, D. G., Cleij, T. J., van Zandvoort, M. A., & Post, M. J. (2012). Electrosensitive Polyacrylic Acid/Fibrin Hydrogel Facilitates Cell Seeding and Alignment. Biomacromolecules, 13(5), 1448-1457. https://doi.org/10.1021/bm300161r
    • Seemann, I., Gabriels, K., Visser, N. L., Hoving, S., te Poele, J. A., Pol, J. F., Gijbels, M. J., Janssen, B. J., Van Leeuwen, F. W., Daemen, M. J., Heeneman, S., & Stewart, F. A. (2012). Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature. Radiotherapy and Oncology, 103(2), 143-150. https://doi.org/10.1016/j.radonc.2011.10.011
    • Donners, M. M. P. C., Wolfs, I. M. J., Stoger, L. J., van der Vorst, E. P. C., Pottgens, C. C. H., Heymans, S., Schroen, B., Gijbels, M. J. J., & de Winther, M. P. J. (2012). Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice. PLOS ONE, 7(4), Article e35877. https://doi.org/10.1371/journal.pone.0035877
    • Liao, X., Sluimer, J. C., Wang, Y.-J., Subramanian, M., Brown, K., Pattison, J. S., Robbins, J., Martinez, J., & Tabas, I. (2012). Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis. Cell Metabolism, 15(4), 545-553. https://doi.org/10.1016/j.cmet.2012.01.022
    • Doering, Y., Manthey, H. D., Drechsler, M., Lievens, D., Megens, R. T. A., Soehnlein, O., Busch, M., Manca, M., Koenen, R. R., Pelisek, J., Daemen, M. J., Lutgens, E., Zenke, M., Binder, C. J., Weber, C., & Zernecke, A. (2012). Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis. Circulation, 125(13), 1673-U190. https://doi.org/10.1161/CIRCULATIONAHA.111.046755
    • Segers, F. M. E., Yu, H., Molenaar, T. J. M., Prince, P., Tanaka, T., van Berkel, T. J. C., & Biessen, E. A. L. (2012). Design and Validation of a Specific Scavenger Receptor Class AI Binding Peptide for Targeting the Inflammatory Atherosclerotic Plaque. Arteriosclerosis Thrombosis and Vascular Biology, 32(4), 971-U285. https://doi.org/10.1161/ATVBAHA.111.235358
    • Bidzhekov, K., Gan, L., Denecke, B., Rostalsky, A., Hristov, M., Koeppel, T. A., Zernecke, A., & Weber, C. (2012). microRNA expression signatures and parallels between monocyte subsets and atherosclerotic plaque in humans. Thrombosis and Haemostasis, 107(4), 619-625. https://doi.org/10.1160/TH11-09-0607
    • Takx, R. A. P., Moscariello, A., Schoepf, U. J., Barraza, J. M. J., Nance, J. W. . J., Bastarrika, G., Das, M., Meyer, M., Wildberger, J. E., Schoenberg, S. O., Fink, C., & Henzler, T. (2012). Quantification of left and right ventricular function and myocardial mass: Comparison of low-radiation dose 2nd generation dual-source CT and cardiac MRI. European Journal of Radiology, 81(4), E598-E604. https://doi.org/10.1016/j.ejrad.2011.07.001
    • Grommes, J., Alard, J.-E., Drechsler, M., Wantha, S., Morgelin, M., Kuebler, W. M., Jacobs, M., von Hundelshausen, P., Markart, P., Wygrecka, M., Preissner, K. T., Hackeng, T. M., Koenen, R. R., Weber, C., & Soehnlein, O. (2012). Disruption of Platelet-derived Chemokine Heteromers Prevents Neutrophil Extravasation in Acute Lung Injury. American Journal of Respiratory and Critical Care Medicine, 185(6), 628-636. https://doi.org/10.1164/rccm.201108-1533OC
    • Versluis, B., Dremmen, M. H. G., Nelemans, P. J., Wildberger, J. E., Schurink, G.-W., Leiner, T., & Backes, W. H. (2012). MRI of Arterial Flow Reserve in Patients with Intermittent Claudication: Feasibility and Initial Experience. PLOS ONE, 7(3), Article e31514. https://doi.org/10.1371/journal.pone.0031514
    • Dittmar, R., Potier, E., van Zandvoort, M., & Ito, K. (2012). Assessment of Cell Viability in Three-Dimensional Scaffolds Using Cellular Auto-Fluorescence. Tissue Engineering. Part C. Methods , 18(3), 198-204. https://doi.org/10.1089/ten.tec.2011.0334
    • Megens, R. T. A., Vijayan, S., Lievens, D., Doering, Y., van Zandvoort, M. A. M. J., Grommes, J., Weber, C., & Soehnlein, O. (2012). Presence of luminal neutrophil extracellular traps in atherosclerosis. Thrombosis and Haemostasis, 107(3), 597-598. https://doi.org/10.1160/TH11-09-0650
    • van de Weijer, T., van Ewijk, P. A., Zandbergen, H. R., Slenter, J. M., Kessels, A. G., Wildberger, J. E., Hesselink, M. K. C., Schrauwen, P., Schrauwen-Hinderling, V. B., & Kooi, M. E. (2012). Geometrical models for cardiac MRI in rodents: comparison of quantification of left ventricular volumes and function by various geometrical models with a full-volume MRI data set in rodents.American Journal of Physiology-heart and Circulatory Physiology, 302(3), H709-H715. https://doi.org/10.1152/ajpheart.00710.2011
    • Knottnerus, I. L. H., Winckers, K., ten Cate, H., Hackeng, T. M., Lodder, J., Rouhl, R. P. W., Staals, J., Govers-Riemslag, J. W. P., Bekers, O., & van Oostenbrugge, R. J. (2012). Levels of heparin-releasable TFPI are increased in first-ever lacunar stroke patients. Neurology, 78(7), 493-498. https://doi.org/10.1212/WNL.0b013e318246d6b7
    • Rowinska, Z., Zander, S., Zernecke, A., Jacobs, M., Langer, S., Weber, C., Merx, M. W., & Koeppel, T. A. (2012). Non- invasive in vivo analysis of a murine aortic graft using high resolution ultrasound microimaging. European Journal of Radiology, 81(2), 244-249. https://doi.org/10.1016/j.ejrad.2010.12.083
    • Doering, Y., Noels, H., & Weber, C. (2012). The Use of High-Throughput Technologies to Investigate Vascular Inflammation and Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 32(2), 182-195. https://doi.org/10.1161/ATVBAHA.111.232686
    • Goossens, G. H., Essers, Y., Konings, E., Jocken, J. W. E., Blaak, E. E., Bizzarri, A., Cajlakovic, M., Ribitsch, V., Clement, K., Venteclef, N., & Cleutjens, J. P. (2012). Response to Letter Regarding Article, "Increased Adipose Tissue Oxygen Tension in Obese Compared With Lean Men Is Accompanied by Insulin Resistance, Impaired Adipose Tissue Capillarization, and Inflammation". Circulation, 125(4), E316-E316. https://doi.org/10.1161/CIRCULATIONAHA.111.068452
    • Huijts, M., Duits, A., Staals, J., & van Oostenbrugge, R. J. (2012). Association of Vitamin B12 Deficiency with Fatigue and Depression after Lacunar Stroke. PLOS ONE, 7(1), Article e30519. https://doi.org/10.1371/journal.pone.0030519
    • Yu, H., Bot, I., Sliedregt-Bol, K., Xu, X., Bot, M., van Heiningen, S. H., van der Marel, G. A., Bennett, M. R., Overkleeft, H., van Berkel, T. J. C., & Biessen, E. A. L. (2012). Selective Modulation of Nuclear Factor of Activated T-Cell Function in Restenosis by a Potent Bipartite Peptide Inhibitor. Circulation Research, 110(2), 200–210. https://doi.org/10.1161/CIRCRESAHA.111.240895