• 2011
    • Koenen, R. R., & Weber, C. (2011). Chemokines: established and novel targets in atherosclerosis. EMBO Molecular Medicine, 3(12), 713-725. https://doi.org/10.1002/emmm.201100183
    • Butoi, E. D., Gan, A. M., Manduteanu, I., Stan, D., Calin, M., Pirvulescu, M., Koenen, R. R., Weber, C., & Simionescu, M. (2011). Cross talk between smooth muscle cells and monocytes/activated monocytes via CX3CL1/CX3CR1 axis augments expression of pro-atherogenic molecules. Biochimica et Biophysica Acta-Molecular Cell Research, 1813(12), 2026-2035. https://doi.org/10.1016/j.bbamcr.2011.08.009
    • Kuijpers, M. J. E., Megens, R. T. A., Nikookhesal, E., Feijge, M. A. H., De Mey, J. G. R., Egbrink, M. G. A. O., van Giezen, J. J. J., & Heemskerk, J. W. M. (2011). Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y(12) antagonist ticagrelor. Thrombosis and Haemostasis, 106(6), 1179-1188. https://doi.org/10.1160/TH11-04-0252
    • Liehn, E. A., Tuchscheerer, N., Kanzler, I., Drechsler, M., Fraemohs, L., Schuh, A., Koenen, R. R., Zander, S., Soehnlein, O., Hristov, M., Grigorescu, G., Urs, A. O., Leabu, M., Bucur, I., Merx, M. W., Zernecke, A., Ehling, J., Gremse, F., Lammers, T., ... Weber, C. (2011). Double-Edged Role of the CXCL12/CXCR4 Axis in Experimental Myocardial Infarction. Journal of the American College of Cardiology, 58(23), 2415-2423. https://doi.org/10.1016/j.jacc.2011.08.033
    • Weber, C., & Noels, H. (2011). Atherosclerosis: current pathogenesis and therapeutic options. Nature Medicine, 17(11), 1410-1422. https://doi.org/10.1038/nm.2538
    • Engel, D., Beckers, L., Wijnands, E., Seijkens, T., Lievens, D., Drechsler, M., Gerdes, N., Soehnlein, O., Daemen, M. J. A. P., Stan, R. V., Biessen, E. A. L., & Lutgens, E. (2011). Caveolin-1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T-cell response. Faseb Journal, 25(11), 3838-3848. https://doi.org/10.1096/fj.11-183350
    • Wolfs, I. M. J., Donners, M. M. P. C., & de Winther, M. P. J. (2011). Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation. Thrombosis and Haemostasis, 106(5), 763-771. https://doi.org/10.1160/TH11-05-0320
    • Reitsma, S., Egbrink, M. G. A. O., Heijnen, V. V. T., Megens, R. T. A., Engels, W., Vink, H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2011). Endothelial glycocalyx thickness and platelet-vessel wall interactions during atherogenesis. Thrombosis and Haemostasis, 106(5), 939-946. https://doi.org/10.1160/TH11-02-0133
    • Bot, I., & Biessen, E. A. L. (2011). Mast cells in atherosclerosis. Thrombosis and Haemostasis, 106(5), 820-826. https://doi.org/10.1160/TH11-05-0291
    • Laeremans, H., Hackeng, T. M., van Zandvoort, M. A. M. J., Thijssen, V. L. J. L., Janssen, B. J. A., Ottenheijm, H. C. J., Smits, J. F. M., & Blankesteijn, W. M. (2011). Blocking of Frizzled Signaling With a Homologous Peptide Fragment of Wnt3a/Wnt5a Reduces Infarct Expansion and Prevents the Development of Heart Failure After Myocardial Infarction. Circulation, 124(15), 1626-U107. https://doi.org/10.1161/CIRCULATIONAHA.110.976969
    • Landry, G., Granton, P. V., Reniers, B., Ollers, M. C., Beaulieu, L., Wildberger, J. E., & Verhaegen, F. (2011). Simulation study on potential accuracy gains from dual energy CT tissue segmentation for low-energy brachytherapy Monte Carlo dose calculations. Physics in Medicine and Biology, 56(19), 6257-6278. https://doi.org/10.1088/0031-9155/56/19/007
    • Soehnlein, O., Wantha, S., Simsekyilmaz, S., Doering, Y., Megens, R. T. A., Mause, S. F., Drechsler, M., Smeets, R., Weinandy, S., Schreiber, F., Gries, T., Jockenhoevel, S., Moeller, M., Vijayan, S., van Zandvoort, M. A. M. J., Agerberth, B., Pham, C. C. T. N., Gallo, R. L., Hackeng, T. M., ... Weber, C. (2011). Neutrophil-Derived Cathelicidin Protects from Neointimal Hyperplasia. Science Translational Medicine, 3(103), 10. https://doi.org/10.1126/scitranslmed.3002531
    • Hoving, S., Heeneman, S., Gijbels, M. J. J., Poele, J. A. M. T., Pol, J. F. C., Gabriels, K., Russell, N. S., Daernen, M. J. A. P., & Stewart, F. A. (2011). Anti-inflammatory and anti-thrombotic intervention strategies using atorvastatin, clopidogrel and knock-down of CD40L do not modify radiation-induced atherosclerosis in ApoE null mice. Radiotherapy and Oncology, 101(1), 100-108. https://doi.org/10.1016/j.radonc.2011.09.019
    • Poggi, M., Engel, D., Christ, A., Beckers, L., Wijnands, E., Boon, L., Driessen, A., Cleutjens, J., Weber, C., Gerdes, N., & Lutgens, E. (2011). CD40L Deficiency Ameliorates Adipose Tissue Inflammation and Metabolic Manifestations of Obesity in Mice. Arteriosclerosis Thrombosis and Vascular Biology, 31(10), 2251-U248. https://doi.org/10.1161/ATVBAHA.111.231357
    • van Almen, G. C., Verhesen, W., van Leeuwen, R. E. W., van de Vrie, M., Eurlings, C., Schellings, M. W. M., Swinnen, M., Cleutjens, J. P. M., van Zandvoort, M. A. M. J., Heymans, S., & Schroen, B. (2011). MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. Aging Cell, 10(5), 769-779. https://doi.org/10.1111/j.1474-9726.2011.00714.x
    • Weijs, B., Blaauw, Y., Rennenberg, R. J. M. W., Schurgers, L. J., Timmermans, C. C. M. M., Pison, L., Nieuwlaat, R., Hofstra, L., Kroon, A. A., Wildberger, J., & Crijns, H. J. G. M. (2011). Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients. European Heart Journal, 32(20), 2555-2562. https://doi.org/10.1093/eurheartj/ehr226
    • van Almen, G. C., Swinnen, M., Carai, P., Verhesen, W., Cleutjens, J. P. M., D'hooge, J., Verheyen, F. K., Pinto, Y. M., Schroen, B., Carmeliet, P., & Heymans, S. (2011). Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy. Journal of Molecular and Cellular Cardiology, 51(3), 318-328. https://doi.org/10.1016/j.yjmcc.2011.05.010
    • Hoff, E. I., Steinbusch, H. W. M., van Oostenbrugge, R. J., Garrett, L., Otte, W. M., van der Marel, K., & Dijkhuizen, R. M. (2011). Alterations in the cholinergic system after frontal cortical infarction in rat brain: Pharmacological magnetic resonance imaging of muscarinic receptor responsiveness and stereological analysis of cholinergic forebrain neurons. Neurobiology of Disease, 43(3), 625-634. https://doi.org/10.1016/j.nbd.2011.05.011
    • Landry, G., Reniers, B., Granton, P. V., van Rooijen, B. D., Beaulieu, L., Wildberger, J. E., & Verhaegen, F. (2011). Extracting atomic numbers and electron densities from a dual source dual energy CT scanner: Experiments and a simulation model. Radiotherapy and Oncology, 100(3), 375-379. https://doi.org/10.1016/j.radonc.2011.08.029
    • Vasina, E. M., Cauwenberghs, S., Feijge, M. A. H., Heemskerk, J. W. M., Weber, C., & Koenen, R. R. (2011). Microparticles from apoptotic platelets promote resident macrophage differentiation. Cell Death & Disease, 2, 10. Article e211. https://doi.org/10.1038/cddis.2011.94
    • Cheng, C., Tempel, D., Den Dekker, W. K., Haasdijk, R. A., Chrifi, I., Bos, F. L., Wagtmans, K., Van De Kamp, E. H. M., Blonden, L. A. J., Biessen, E. A. L., Moll, F. L., Pasterkamp, G., Serruys, P. W., Schulte-Merker, S., & Duckers, H. J. (2011). Ets2 Determines the Inflammatory State of Endothelial Cells in Advanced Atherosclerotic Lesions. Circulation Research, 109(4), 385-395. https://doi.org/10.1161/CIRCRESAHA.111.243444
    • Goossens, P., Vergouwe, M. N., Gijbels, M. J. J., Curfs, D. M. J., van Woezik, J. H. G., Hoeksema, M. A., Xanthouleas, S., Leenen, P. J. M., Rupec, R. A., Hofker, M. H., & de Winther, M. P. J. (2011). Myeloid I kappa B alpha Deficiency Promotes Atherogenesis by Enhancing Leukocyte Recruitment to the Plaques. PLOS ONE, 6(7), 8. https://doi.org/10.1371/journal.pone.0022327
    • Goossens, G. H., Bizzarri, A., Venteclef, N., Essers, Y., Cleutjens, J. P. M., Konings, E., Jocken, J. W., Cajlakovic, M., Ribitsch, V., Clement, K., & Blaak, E. E. (2011). Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation. Circulation, 124(1), 67-76. https://doi.org/10.1161/CIRCULATIONAHA.111.027813
    • Weber, C., Meiler, S., Doering, Y., Koch, M., Drechsler, M., Megens, R. T. A., Rowinska, Z., Bidzhekov, K., Fecher, C., Ribechini, E., van Zandvoort, M. A. M. J., Binder, C. J., Jelinek, I., Hristov, M., Boon, L., Jung, S., Korn, T., Lutz, M. B., Foerster, I., ... Zernecke, A. (2011). CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. Journal of Clinical Investigation, 121(7), 2898-2910. https://doi.org/10.1172/JCI44925
    • Steegh, F. M., Gelens, M. A., Nieman, F. H. M., van Hooff, J. P., Cleutjens, J. P., van Suylen, R. J., Daemen, M. J., van Heurn, E. L., Christiaans, M. H., & Peutz-Kootstra, C. J. (2011). Early loss of peritubular capillaries after kidney transplantation.Journal of the American Society of Nephrology, 22(6), 1024-1029. https://doi.org/10.1681/ASN.2010050531
    • Roijers, R. B., Debernardi, N., Cleutjens, J. P. M., Schurgers, L. J., Mutsaers, P. H. A., & van der Vusse, G. J. (2011). Microcalcifications in Early Intimal Lesions of Atherosclerotic Human Coronary Arteries. American Journal of Pathology, 178(6), 2879-2887. https://doi.org/10.1016/j.ajpath.2011.02.004
    • Zhou, Z., Subramanian, P., Sevilmis, G., Globke, B., Soehnlein, O., Karshovska, E., Megens, R., Heyll, K., Chun, J., Saulnier-Blache, J. S., Reinholz, M., van Zandvoort, M., Weber, C., & Schobert, A. (2011). Lipoprotein-Derived Lysophosphatidic Acid Promotes Atherosclerosis by Releasing CXCL1 from the Endothelium. Cell Metabolism, 13(5), 592-600. https://doi.org/10.1016/j.cmet.2011.02.016
    • Kemerink, M., Dierichs, T. J., Dierichs, J., Huynen, H. J. M., Wildberger, J. E., van Engelshoven, J. M. A., & Kemerink, G. J. (2011). Characteristics of a First-Generation X-Ray System. Radiology, 259(2), 534-539. https://doi.org/10.1148/radiol.11101899
    • Megens, R. T. A., Kemmerich, K., Pyta, J., Weber, C., & Soehnlein, O. (2011). Intravital imaging of phagocyte recruitment. Thrombosis and Haemostasis, 105(5), 802-810. https://doi.org/10.1160/TH10-11-0735
    • Ferns, S. P., Sprengers, M. E. S., van Rooij, W. J., van Zwam, W. H., de Kort, G. A. P., Velthuis, B. K., Schaafsma, J. D., van den Berg, R., Sluzewski, M., Brouwer, P. A., Rinkel, G. J. E., & Majoie, C. B. L. M. (2011). Late Reopening of Adequately Coiled Intracranial Aneurysms Frequency and Risk Factors in 400 Patients With 440 Aneurysms. Stroke, 42(5), 1331-1337. https://doi.org/10.1161/STROKEAHA.110.605790
    • Kwee, R. M., Truijman, M. T. B., Mess, W. H., Teule, G. J. J., Ter Berg, J. W., Franke, CL., Korten, A. G., Meems, B. J., Prins, M. H., van Engelshoven, J. M. A., Wildberger, J. E., van Oostenbrugge, R. J., & Kooi, M. E. (2011). Potential of integrated (18F) fluordeoxyglucose positron-emission tomography/CT in identifying vulnerable carotid plaques. American Journal of Neuroradiology, 32(5), 950-954. https://doi.org/10.3174/ajnr.A2381
    • Dirks, M., Niessen, L. W., van Wijngaarden, J. D. H., Koudstaal, P. J., Franke, C. L., van Oostenbrugge, R. J., Huijsman, R., Lingsma, H. F., Minkman, M. M. N., & Dippel, D. W. J. (2011). Promoting Thrombolysis in Acute Ischemic Stroke. Stroke, 42(5), 1325-1330. https://doi.org/10.1161/STROKEAHA.110.596940
    • Mahnken, A. H., Klotz, E., Schreiber, S., Bruners, P., Isfort, P., Guenther, R. W., & Wildberger, J. E. (2011). Volumetric Arterial Enhancement Fraction Predicts Tumor Recurrence After Hepatic Radiofrequency Ablation of Liver Metastases: Initial Results. American Journal of Roentgenology, 196(5), W573-W579. https://doi.org/10.2214/AJR.10.4410
    • van Rijsingen, I. A. W., Bekkers, S. C. A. M., Schalla, S., Hermans-van Ast, J. F., Snoep, G., Alzand, B. S. N., Arens, Y. H. J. M., van den Wijngaard, A., Crijns, H. J. G. M., & Pinto, Y. M. (2011). Exercise related ventricular arrhythmias are related to cardiac fibrosis in hypertrophic cardiomyopathy mutation carriers. Netherlands Heart Journal, 19(4), 168-174. https://doi.org/10.1007/s12471-011-0090-8
    • Bauwens, M., De Saint-Hubert, M., Devos, E., Deckers, N., Reutelingsperger, C. P. M., Mortelmans, L., Himmelreich, U., Mottaghy, F. M., & Verbruggen, A. M. (2011). Site-specific Ga-68-labeled Annexin A5 as a PET imaging agent for apoptosis. Nuclear Medicine and Biology, 38(3), 381-392. https://doi.org/10.1016/j.nucmedbio.2010.09.008
    • Kramp, B. K., Sarabi, A., Koenen, R. R., & Weber, C. (2011). Heterophilic chemokine receptor interactions in chemokine signaling and biology. Experimental Cell Research, 317(5), 655-663. https://doi.org/10.1016/j.yexcr.2010.11.014
    • Lambregts, D. M., Beets, G. L., Maas, M., Kessels, A. G. H., Bakers, F. C., Cappendijk, V. C., Engelen, S. M., Lahaye, M. J., de Bruine, A. P., Lammering, G., Leiner, T., Verwoerd, J. L., Wildberger, J. E., & Beets Tan, R. G. (2011). Accuracy of Gadofosveset-enhanced MRI for Nodal Staging and Restaging in Rectal Cancer. Annals of Surgery, 253(3), 539-545. https://doi.org/10.1097/SLA.0b013e31820b01f1
    • Bilet, L., van de Weijer, T., Hesselink, M. K. C., Glatz, J. F., Lamb, H. J., Wildberger, J. E., Kooi, M. E., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2011). Exercise-induced modulation of cardiac lipid content in healthy lean young men. Basic Research in Cardiology, 106(2), 307-315. https://doi.org/10.1007/s00395-010-0144-x
    • Klompenhouwer, E. G., Dings, J. T. A., van Oostenbrugge, R. J., Oei, S., Wilmink, J. T., & van Zwam, W. H. (2011). Single-Center Experience of Surgical and Endovascular Treatment of Ruptured Intracranial Aneurysms. American Journal of Neuroradiology, 32(3), 570-575. https://doi.org/10.3174/ajnr.A2326
    • de Jager, S. C. A., Bermudez, B., Bot, I., Koenen, R. R., Bot, M., Kavelaars, A., de Waard, V., Heijnen, C. J., Muriana, F. J. G., Weber, C., van Berkel, T. J. C., Kuiper, J., Lee, S.-J., Abia, R., & Biessen, E. A. L. (2011). Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis. Journal of Experimental Medicine, 208(2), 217-225. https://doi.org/10.1084/jem.20100370
    • Bot, I., Jukema, J. W., Lankhuizen, I. M., van Berkel, T. J. C., & Biessen, E. A. L. (2011). Atorvastatin inhibits plaque development and adventitial neovascularization in ApoE deficient mice independent of plasma cholesterol levels. Atherosclerosis, 214(2), 295-300. https://doi.org/10.1016/j.atherosclerosis.2010.11.008
    • Ferns, S. P., Sprengers, M. E. S., van Rooij, W. J., van den Berg, R., Velthuis, B. K., de Kort, G. A. P., Sluzewski, M., van Zwam, W. H., Rinkel, G. J. E., & Majoie, C. B. L. M. (2011). De Novo Aneurysm Formation and Growth of Untreated Aneurysms A 5-Year MRA Follow-Up in a Large Cohort of Patients With Coiled Aneurysms and Review of the Literature. Stroke, 42(2), 313-318. https://doi.org/10.1161/STROKEAHA.110.591594
    • von der Thüsen, J. H., Borensztajn, K. S., Moimas, S., van Heiningen, S. H., Teeling, P., van Berkel, T. J. C., & Biessen, E. A. L. (2011). IGF-1 Has Plaque-Stabilizing Effects in Atherosclerosis by Altering Vascular Smooth Muscle Cell Phenotype. American Journal of Pathology, 178(2), 924-934. https://doi.org/10.1016/j.ajpath.2010.10.007
    • Kwee, R. M., Hofman, P. A., Gronenschild, E. H., van Oostenbrugge, R. J., Mess, W. H., Ter Berg, J. W., Franke, CL., Korten, A. G., Meems, B. J., van Engelshoven, J. M., Wildberger, J. E., & Kooi, M. E. (2011). Association between carotid plaque characteristics and cerebral white matter lesions: one-year follow-up study by MRI. PLOS ONE, 6(2), Article e17070. https://doi.org/10.1371/journal.pone.0017070
    • Schrauwen-Hinderling, V. B., Meex, R. C., Hesselink, M. K. C., van de Weijer, T., Leiner, T., Schar, M., Lamb, H. J., Wildberger, J. E., Glatz, J. F., Schrauwen, P., & Kooi, M. E. (2011). Cardiac lipid content is unresponsive to a physical activity training intervention in type 2 diabetic patients, despite improved ejection fraction. Cardiovascular Diabetology, 10(1), 47. https://doi.org/10.1186/1475-2840-10-47
    • Henskens, L. H. G., van Boxtel, M. P. J., Kroon, A. A., van Oostenbrugge, R. J., Lodder, J., & de Leeuw, P. W. (2011). Sleep disturbance increases the nocturnal blood pressure level and attenuates the correlation with target organ damage. Journal of Hypertension, 29(2), 242-250. https://doi.org/10.1097/HJH.0b013e32834192d5
    • Sarabi, A., Kramp, B. K., Drechsler, M., Hackeng, T. M., Soehnlein, O., Weber, C., Koenen, R. R., & von Hundelshausen, P. (2011). CXCL4L1 inhibits angiogenesis and induces undirected endothelial cell migration without affecting endothelial cell proliferation and monocyte recruitment. Journal of Thrombosis and Haemostasis, 9(1), 209-219. https://doi.org/10.1111/j.1538-7836.2010.04119.x
    • Versluis, B., Backes, W. H., van Eupen, M. G. A., Jaspers, K., Nelemans, P. J., Rouwet, E. V., Teijink, J. A. W., Mali, W. P. T. M., Schurink, G. W. H., Wildberger, J. E., & Leiner, T. (2011). Magnetic Resonance Imaging in Peripheral Arterial Disease Reproducibility of the Assessment of Morphological and Functional Vascular Status. Investigative Radiology, 46(1), 11-24. https://doi.org/10.1097/RLI.0b013e3181f2bfb8
    • Bot, I., Bot, M., van Heiningen, S. H., van Santbrink, P. J., Lankhuizen, I. M., Hartman, P., Gruener, S., Hilpert, H., van Berkel, T. J. C., Fingerle, J., & Biessen, E. A. L. (2011). Mast cell chymase inhibition reduces atherosclerotic plaque progression and improves plaque stability in ApoE(-/-) mice. Cardiovascular Research, 89(1), 244-252. https://doi.org/10.1093/cvr/cvq260