• 2014
    • van Empel, V. P. M., Kaye, D. M., & Borlaug, B. A. (2014). Effects of Healthy Aging on the Cardiopulmonary Hemodynamic Response to Exercise. American Journal of Cardiology, 114(1), 131-135. https://doi.org/10.1016/j.amjcard.2014.04.011
    • Weinandy, S., Laffar, S., Unger, R. E., Flanagan, T. C., Loesel, R., Kirkpatrick, C. J., van Zandvoort, M., Hermanns-Sachweh, B., Dreier, A., Klee, D., & Jockenhoevel, S. (2014). Biofunctionalized Microfiber-Assisted Formation of Intrinsic Three-Dimensional Capillary-Like Structures. Tissue Engineering, 20(13-14), 1858-1869. https://doi.org/10.1089/ten.tea.2013.0330
    • Lobbes, M. B. I., Lalji, U., Houwers, J., Nijssen, E. C., Nelemans, P. J., van Roozendaal, L., Smidt, M. L., Heuts, E., & Wildberger, J. E. (2014). Contrast-enhanced spectral mammography in patients referred from the breast cancer screening programme. European Radiology, 24(7), 1668-1676. https://doi.org/10.1007/s00330-014-3154-5
    • Vijayan, S., Asare, Y., Grommes, J., Soehnlein, O., Lutgens, E., Shagdarsuren, G., Togtokh, A., Jacobs, M. J., Fischer, J. W., Bernhagen, J., Weber, C., Schober, A., & Shagdarsuren, E. (2014). High Expression of C5L2 Correlates with High Proinflammatory Cytokine Expression in Advanced Human Atherosclerotic Plaques. American Journal of Pathology, 184(7), 2123-2133. https://doi.org/10.1016/j.ajpath.2014.04.004
    • Lagraauw, H. M., Westra, M. M., Bot, M., Wezel, A., van Santbrink, P. J., Pasterkamp, G., Biessen, E. A. L., Kuiper, J., & Bot, I. (2014). Vascular neuropeptide Y contributes to atherosclerotic plaque progression and perivascular mast cell activation. Atherosclerosis, 235(1), 196-203. https://doi.org/10.1016/j.atherosclerosis.2014.04.025
    • Pruessmeyer, J., Hess, F. M., Alert, H., Groth, E., Pasqualon, T., Schwarz, N., Nyamoya, S., Kollert, J., van der Vorst, E., Donners, M., Martin, C., Uhlig, S., Saftig, P., Dreymueller, D., & Ludwig, A. (2014). Leukocytes require ADAM10 but not ADAM17 for their migration and inflammatory recruitment into the alveolar space. Blood, 123(26), 4077-4088. https://doi.org/10.1182/blood-2013-09-511543
    • Vaidya, A., Severens, J. L., Bongaerts, B. W. C., Cleutjens, K. B. J. M., Nelemans, P. J., Hofstra, L., van Dieijen-Visser, M., & Biessen, E. A. L. (2014). High-sensitive Troponin T assay for the diagnosis of acute myocardial infarction: an economic evaluation. BMC Cardiovascular disorders, 14, Article 77. https://doi.org/10.1186/1471-2261-14-77
    • Halvorsen, B., Smedbakken, L. M., Michelsen, A. E., Skjelland, M., Bjerkeli, V., Sagen, E. L., Tasken, K., Bendz, B., Gullestad, L., Holm, S., Biessen, E. A., & Aukrust, P. (2014). Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13. Atherosclerosis, 234(2), 352-359. https://doi.org/10.1016/j.atherosclerosis.2014.03.021
    • Schmitt, M. M. N., Fraemohs, L., Hackeng, T. M., Weber, C., & Koenen, R. R. (2014). Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-A redistribution. Atherosclerosis, 234(2), 254-264. https://doi.org/10.1016/j.atherosclerosis.2014.03.014
    • Noels, H., Zhou, B., Tilstam, P. V., Theelen, W., Li, X., Pawig, L., Schmitz, C., Akhtar, S., Simsekyilmaz, S., Shagdarsuren, E., Schober, A., Adams, R. H., Bernhagen, J., Liehn, E. A., Doering, Y., & Weber, C. (2014). Deficiency of Endothelial Cxcr4 Reduces Reendothelialization and Enhances Neointimal Hyperplasia After Vascular Injury in Atherosclerosis-Prone Mice. Arteriosclerosis Thrombosis and Vascular Biology, 34(6), 1209-1220. https://doi.org/10.1161/ATVBAHA.113.302878
    • Foulquier, S., Boehm, M., Schmieder, R., Sleight, P., Teo, K., Yusuf, S., Schumacher, H., & Unger, T. (2014). Impact of telmisartan on cardiovascular outcome in hypertensive patients at high risk: a Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease subanalysis. Journal of Hypertension, 32(6), 1334-1341. https://doi.org/10.1097/HJH.0000000000000154
    • Lemmens, K. J., van de Wier, B., Vaes, N., Ghosh, M., van Zandvoort, M. A., van der Vijgh, W., Bast, A., & Haenen, G. R. (2014). The flavonoid 7-mono-O-(beta-hydroxyethyl)-rutoside is able to protect endothelial cells by a direct antioxidant effect. Toxicology in Vitro, 28(4), 538-543. https://doi.org/10.1016/j.tiv.2013.12.019
    • Eurlings, I. M. J., Dentener, M. A., Cleutjens, J. P. M., Peutz, C. J., Rohde, G. G. U., Wouters, E. F. M., & Reynaert, N. L. (2014). Similar matrix alterations in alveolar and small airway walls of COPD patients. BMC Pulmonary Medicine, 14(1), Article 90. https://doi.org/10.1186/1471-2466-14-90
    • Projahn, D., Simsekyilmaz, S., Singh, S., Kanzler, I., Kramp, B. K., Langer, M., Burlacu, A., Bernhagen, J., Klee, D., Zernecke, A., Hackeng, T. M., Groll, J., Weber, C., Liehn, E. A., & Koenen, R. R. (2014). Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction. Journal of Cellular and Molecular Medicine, 18(5), 790-800. https://doi.org/10.1111/jcmm.12225
    • Versteylen, M. O., Joosen, I. A., Kietselaer, B. L., Wildberger, J. E., Crijns, H. J., & Hofstra, L. (2014). Gender Difference in the Prognostic Value of CTA?JACC-Cardiovascular Imaging, 7(5), 529-530. https://doi.org/10.1016/j.jcmg.2013.08.018
    • Hanssen, N. M. J., Wouters, K., Huijberts, M. S., Gijbels, M. J., Sluimer, J. C., Scheijen, J. L. J. M., Heeneman, S., Biessen, E. A. L., Daemen, M. J. A. P., Brownlee, M., de Kleijn, D. P., Stehouwer, C. D. A., Pasterkamp, G., & Schalkwijk, C. G. (2014). Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype. European Heart Journal, 35(17), 1137-1146. https://doi.org/10.1093/eurheartj/eht402
    • Gommer, E. D., Bogaarts, G., Martens, E. G. H. J., Mess, W. H., & Reulen, J. P. H. (2014). Visually evoked blood flow responses and interaction with dynamic cerebral autoregulation: Correction for blood pressure variation. Medical Engineering & Physics, 36(5), 613-619. https://doi.org/10.1016/j.medengphy.2014.01.006
    • Sailer, A. M., Douwes, D. C. E., Cappendijk, V. C., Bakers, F. C., Wagemans, B. A. J. M., Wildberger, J. E., Kessels, A. G., & Beets-Tan, R. G. H. (2014). RECIST measurements in cancer treatment: is there a role for physician assistants? - A pilot study. Cancer Imaging, 14(1), Article 12. https://doi.org/10.1186/1470-7330-14-12
    • Bullen, J. W., Balsbaugh, J. L., Chanda, D., Shabanowitz, J., Hunt, D. F., Neumann, D., & Hart, G. W. (2014). Cross-talk between Two Essential Nutrient-sensitive Enzymes O-GlcNAc TRANSFERASE ( OGT) AND AMP-ACTIVATED PROTEIN KINASE ( AMPK). Journal of Biological Chemistry, 289(15), 10592-10606. https://doi.org/10.1074/jbc.M113.523068
    • Halvorsen, B., Dahl, T. B., Smedbakken, L. M., Singh, A., Michelsen, A. E., Skjelland, M., Krohg-Sorensen, K., Russell, D., Hoepken, U. E., Lipp, M., Damas, J. K., Holm, S., Yndestad, A., Biessen, E. A., & Aukrust, P. (2014). Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells. Cardiovascular Research, 102(1), 148-156. https://doi.org/10.1093/cvr/cvu036
    • Sailer, A. M., de Haan, M. W., Peppelenbosch, A. G., Jacobs, M., Wildberger, J. E., & Schurink, G. W. H. (2014). CTA with Fluoroscopy Image Fusion Guidance in Endovascular Complex Aortic Aneurysm Repair. European Journal of Vascular and Endovascular Surgery, 47(4), 349-356. https://doi.org/10.1016/j.ejvs.2013.12.022
    • Kok, M., Mihl, C., Mingels, A. A., Kietselaer, B. L., Muhlenbruch, G., Seehofnerova, A., Wildberger, J. E., & Das, M. (2014). Influence of Contrast Media Viscosity and Temperature on Injection Pressure in Computed Tomographic Angiography A Phantom Study. Investigative Radiology, 49(4), 217-223. https://doi.org/10.1097/RLI.0000000000000019
    • Dittmar, R., van Dijk, B. G. M., van Zandvoort, M. A. M. J., & Ito, K. (2014). In Situ Label-Free Cell Viability Assessment of Nucleus Pulposus Tissue. Journal of Orthopaedic Research, 32(4), 545-550. https://doi.org/10.1002/jor.22576
    • Schober, A., Nazari-Jahantigh, M., Wei, Y., Bidzhekov, K., Gremse, F., Grommes, J., Megens, R. T. A., Heyll, K., Noels, H., Hristov, M., Wang, S., Kiessling, F., Olson, E. N., & Weber, C. (2014). MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1. Nature Medicine, 20(4), 368–376. https://doi.org/10.1038/nm.3487
    • Tijssen, M. P. M., Hofman, P. A. M., Stadler, A. A. R., van Zwam, W., de Graaf, R., van Oostenbrugge, R. J., Klotz, E., Wildberger, J. E., & Postma, A. A. (2014). The role of dual energy CT in differentiating between brain haemorrhage and contrast medium after mechanical revascularisation in acute ischaemic stroke. European Radiology, 24(4), 834-840. https://doi.org/10.1007/s00330-013-3073-x
    • El Aidi, H., Adams, A., Moons, K. G. M., Den Ruijter, H. M., Mali, W. P. T. M., Doevendans, P. A., Nagel, E., Schalla, S., Bots, M. L., & Leiner, T. (2014). Cardiac Magnetic Resonance Imaging Findings and the Risk of Cardiovascular Events in Patients With Recent Myocardial Infarction or Suspected or Known Coronary Artery Disease. Journal of the American College of Cardiology, 63(11), 1031-1045. https://doi.org/10.1016/j.jacc.2013.11.048
    • Chatzigeorgiou, A., Seijkens, T., Zarzycka, B., Engel, D., Poggi, M., van den Berg, S., van den Berg, S., Soehnlein, O., Winkels, H., Beckers, L., Lievens, D., Driessen, A., Kusters, P., Biessen, E., Garcia-Martin, R., Klotzsche-von Ameln, A., Gijbels, M., Noelle, R., Boon, L., ... Lutgens, E. (2014). Correction for Chatzigeorgiou et al., Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance (vol 111, pg 2686, 2014). Proceedings of the National Academy of Sciences of the United States of America, 111(12), 4644-4644. https://doi.org/10.1073/pnas.1403231111
    • Li, X., Zhu, M., Penfold, M. E., Koenen, R. R., Thiemann, A., Heyll, K., Akhtar, S., Koyadan, S., Wu, Z., Gremse, F., Kiessling, F., van Zandvoort, M., Schall, T. J., Weber, C., & Schober, A. (2014). Activation of CXCR7 Limits Atherosclerosis and Improves Hyperlipidemia by Increasing Cholesterol Uptake in Adipose Tissue. Circulation, 129(11), 1244-1253. https://doi.org/10.1161/CIRCULATIONAHA.113.006840
    • Sanders-van Wijk, S., van Empel, V., Knackstedt, C., & Brunner-La Rocca, H.-P. (2014). Heart failure and COPD: Time to SHIFT?International Journal of Cardiology, 172(2), 293-294. https://doi.org/10.1016/j.ijcard.2013.12.285
    • Doering, Y., Noels, H., Mandl, M., Kramp, B., Neideck, C., Lievens, D., Drechsler, M., Megens, R. T. A., Tilstam, P. V., Langer, M., Hartwig, H., Theelen, W., Marth, J. D., Sperandio, M., Soehnlein, O., & Weber, C. (2014). Deficiency of the Sialyltransferase St3Gal4 Reduces-Ccl5Mediated Myeloid Cell Recruitment and Arrest. Circulation Research, 114(6), 976-981. https://doi.org/10.1161/CIRCRESAHA.114.302426
    • van Empel, V. P. M., Lee, J., Williams, T. J., & Kaye, D. M. (2014). Iron deficiency in patients with idiopathic pulmonary arterial hypertension. Heart Lung and Circulation, 23(3), 287-92. https://doi.org/10.1016/j.hlc.2013.08.007
    • Gabriels, K., Hoving, S., Gijbels, M. J., Pol, J. F., te Poele, J. A., Biessen, E. A., Daemen, M. J., Stewart, F. A., & Heeneman, S. (2014). Irradiation of existing atherosclerotic lesions increased inflammation by favoring pro-inflammatory macrophages. Radiotherapy and Oncology, 110(3), 455-460. https://doi.org/10.1016/j.radonc.2014.01.006
    • Chevre, R., Maria Gonzalez-Granado, J., Megens, R. T. A., Sreeramkumar, V., Silvestre-Roig, C., Molina-Sanchez, P., Weber, C., Soehnlein, O., Hidalgo, A., & Andres, V. (2014). High-Resolution Imaging of Intravascular Atherogenic Inflammation in Live Mice. Circulation Research, 114(5), 770-779. https://doi.org/10.1161/CIRCRESAHA.114.302590
    • Chatzigeorgioua, A., Seijkens, T., Zarzycka, B., Engel, D., Poggi, M., van den Berg, S., van den Berg, S., Soehnlein, O., Winkels, H., Beckers, L., Lievens, D., Driessen, A., Kusters, P., Biessen, E., Garcia-Martin, R., Ameln, A. K., Gijbels, M., Noelle, R., Boon, L., ... Lutgens, E. (2014). Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance. Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2686-2691. https://doi.org/10.1073/pnas.1400419111
    • Wildhagen, K. C. A. A., Garcia de Frutos, P., Reutelingsperger, C. P., Schrijver, R., Areste, C., Ortega-Gomez, A., Deckers, N. M., Hemker, H. C., Soehnlein, O., & Nicolaes, G. A. F. (2014). Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis. Blood, 123(7), 1098-1101. https://doi.org/10.1182/blood-2013-07-514984
    • Versluis, B., Nelemans, P. J., Brans, R., Wildberger, J. E., Schurink, G. W., Leiner, T., & Backes, W. H. (2014). Functional MRI in Peripheral Arterial Disease: Arterial Peak Flow versus Ankle-Brachial Index. PLOS ONE, 9(2), Article e88471. https://doi.org/10.1371/journal.pone.0088471
    • Tilstam, P. V., Gijbels, M. J., Habbeddine, M., Cudejko, C., Asare, Y., Theelen, W., Zhou, B., Doering, Y., Drechsler, M., Pawig, L., Simsekyilmaz, S., Koenen, R. R., de Winther, M. P. J., Lawrence, T., Bernhagen, J., Zernecke, A., Weber, C., & Noels, H. (2014). Bone Marrow-Specific Knock-In of a Non-Activatable Ikk alpha Kinase Mutant Influences Haematopoiesis but Not Atherosclerosis in Apoe-Deficient Mice. PLOS ONE, 9(2), Article e87452. https://doi.org/10.1371/journal.pone.0087452
    • Aoqui, C., Chmielewski, S., Scherer, E., Eissler, R., Sollinger, D., Heid, I., Braren, R., Schmaderer, C., Megens, R. T. A., Weber, C., Heemann, U., Tschoep, M., & Baumann, M. (2014). Microvascular dysfunction in the course of metabolic syndrome induced by high-fat diet. Cardiovascular Diabetology, 13, Article 31. https://doi.org/10.1186/1475-2840-13-31
    • Namsolleck, P., Recarti, C., Foulquier, S., Steckelings, U. M., & Unger, T. (2014). AT(2) Receptor and Tissue Injury: Therapeutic Implications. Current Hypertension Reports, 16(2), Article 416. https://doi.org/10.1007/s11906-013-0416-6
    • Van Empel, V. P. M., Kaufmann, B. A., Bernheim, A. M., Goetschalckx, K., Min, S. Y., Muzzarelli, S., Pfisterer, M. E., Kiencke, S., Maeder, M. T., & Brunner-La Rocca, H.-P. (2014). Interaction Between Pulmonary Hypertension and Diastolic Dysfunction in an Elderly Heart Failure Population. Journal of Cardiac Failure, 20(2), 98-104. https://doi.org/10.1016/j.cardfail.2013.12.010
    • Jaczewska, J., Abdulreda, M. H., Yau, C. Y., Schmitt, M. M., Schubert, I., Berggren, P.-O., Weber, C., Koenen, R. R., Moy, V. T., & Wojcikiewicz, E. P. (2014). TNF-alpha and IFN-gamma promote lymphocyte adhesion to endothelial junctional regions facilitating transendothelial migration. Journal of Leukocyte Biology, 95(2), 265-274. https://doi.org/10.1189/jlb.0412205
    • Campos, D. F. D., Vogt, M., Lindner, M., Kirsten, A., Weber, M., Megens, R. T. A., Pyta, J., Zenke, M., Van Zandvoort, M., & Fischer, H. (2014). Two-Photon Laser Scanning Microscopy as a Useful Tool for Imaging and Evaluating Macrophage-, IL-4 Activated Macrophage-and Osteoclast-based In Vitro Degradation of Beta-Tricalcium Phosphate Bone Substitute Material. Microscopy Research and Technique, 77(2), 143-152. https://doi.org/10.1002/jemt.22321
    • Schlijper, R. C. J., Grutters, J. P. C., Houben, R., Dingemans, A.-M. C., Wildberger, J. E., Van Raemdonck, D., Van Cutsem, E., Haustermans, K., Lammering, G., Lambin, P., & De Ruysscher, D. (2014). What to choose as radical local treatment for lung metastases from cob-rectal cancer: Surgery or radiofrequency ablation?Cancer Treatment Reviews, 40(1), 60-67. https://doi.org/10.1016/j.ctrv.2013.05.004
    • Wijnands, K. A., Hoeksema, M. A., Meesters, D. M., van den Akker, N. M., Molin, D. G., Briede, J. J., Ghosh, M., Kohler, S. E., van Zandvoort, M. A., de Winther, M. P., Buurman, W. A., Lamers, W. H., & Poeze, M. (2014). Arginase-1 Deficiency Regulates Arginine Concentrations and NOS2-Mediated NO Production during Endotoxemia. PLOS ONE, 9(1), Article e86135. https://doi.org/10.1371/journal.pone.0086135
    • Schmitt, M. M. N., Megens, R. T. A., Zernecke, A., Bidzhekov, K., van den Akker, N. M., Rademakers, T., van Zandvoort, M. A., Hackeng, T. M., Koenen, R. R., & Weber, C. (2014). Endothelial Junctional Adhesion Molecule-A Guides Monocytes Into Flow-Dependent Predilection Sites of Atherosclerosis. Circulation, 129(1), 66–76. https://doi.org/10.1161/CIRCULATIONAHA.113.004149
    • Mihl, C., Loeffen, D., Versteylen, M. O., Takx, R. A. P., Nelemans, P. J., Nijssen, E. C., Vega-Higuera, F., Wildberger, J. E., & Das, M. (2014). Automated quantification of epicardial adipose tissue (EAT) in coronary CT angiography; comparison with manual assessment and correlation with coronary artery disease. Journal of Cardiovascular Computed Tomography, 8(3), 215-221. https://doi.org/10.1016/j.jcct.2014.04.003
    • Sailer, A. M. H., Wagemans, B. A. J. M., Nelemans, P. J., de Graaf, R., & van Zwam, W. H. (2014). Diagnosing Intracranial Aneurysms With MR Angiography: Systematic Review and Meta-Analysis. Stroke, 45(1), 119-126. https://doi.org/10.1161/STROKEAHA.113.003133
    • Gaens, K. H., Goossens, G. H., Niessen, P. M., van Greevenbroek, M. M., van der Kallen, C. J., Niessen, H. W., Rensen, S. S., Buurman, W. A., Greve, J. W., Blaak, E. E., van Zandvoort, M. A., Bierhaus, A., Stehouwer, C. D., & Schalkwijk, C. G. (2014). Nε-(Carboxymethyl)lysine-Receptor for Advanced Glycation End Product Axis Is a Key Modulator of Obesity-Induced Dysregulation of Adipokine Expression and Insulin Resistance. Arteriosclerosis Thrombosis and Vascular Biology, 34(6), 1199-1208. https://doi.org/10.1161/ATVBAHA.113.302281
    • Marsch, E., Theelen, T. L., Demandt, J. A., Jeurissen, M., van Gink, M., Verjans, R., Janssen, A., Cleutjens, J. P., Meex, S. J., Donners, M. M., Haenen, G., Schalkwijk, C. G., Dubois, L. J., Lambin, P., Mallat, Z., Gijbels, M. J., Heemskerk, J. W., Fisher, E. A., Biessen, E. A., ... Sluimer, J. C. (2014). Reversal of hypoxia in murine atherosclerosis prevents necrotic core expansion by enhancing efferocytosis. Arteriosclerosis Thrombosis and Vascular Biology, 34(12), 2545-2553. https://doi.org/10.1161/ATVBAHA.114.304023
    • Jetten, N., Verbruggen, S., Gijbels, M. J., Post, M. J., De Winther, M. P. J., & Donners, M. M. P. C. (2014). Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo. Angiogenesis, 17(1), 109-118. https://doi.org/10.1007/s10456-013-9381-6