Publications
- 2025
- Ruthmann, F., Lo, J. W., Mendyk-Bordet, A.-M., Allart, E., Köhler, S., Klimkowicz-Mrowiec, A., Staals, J., Sachdev, P. S., Bordet, R., Dondaine, T., & Stroke and Cognition (STROKOG) Collaboration (2025). Prevalence of poststroke anxiety and its associations with global cognitive impairment: An individual participant data analysis. Journal of Affective Disorders, 369, 1136-1144. https://doi.org/10.1016/j.jad.2024.10.099
- Zhao, H., Xu, Z., Chen, L., Wu, L., Cui, Z., Ma, J., Sun, T., Lei, Y., Wang, N., Hu, H., Tan, Y., Lu, W., Yang, W., Liao, K., Teng, G., Liang, X., Li, Y., Feng, C., Nie, T., ... Zheng, C. (2025). Large-scale pretrained frame generative model enables real-time low-dose DSA imaging: An AI system development and multi-center validation study. Med, 6(1), Article 100497. https://doi.org/10.1016/j.medj.2024.07.025
- Baker, A. H., Giacca, M., & Thum, T. (2025). miRNA discovery to therapy: The field is sufficiently mature to assess the value of miRNA-based therapeutics. Molecular Therapy, 33(1), 3-4. https://doi.org/10.1016/j.ymthe.2024.12.024
- Weber, C., Rigby, A., & Lip, G. Y. H. (2025). Thrombosis and Haemostasis 2024 Editors' Choice Papers. Thrombosis and Haemostasis, 125(01), 85-91. https://doi.org/10.1055/a-2495-1993
- Lip, G. Y. H., Rigby, A., & Weber, C. (2025). Welcoming 2025-A Year of Collaboration and Progress. Thrombosis and Haemostasis, 125(01), 1-2. https://doi.org/10.1055/a-2495-2105
- Ceulemans, A., Barakzie, A., Spronk, H. M. H., de Maat, M. P. M., van Beusekom, H. M. M., Taha, A., Emmer, B. J., Roos, Y. B. W. E. M., Dippel, D. W. J., Majoie, C. B. L. M., van Zwam, W. H., ten Cate, H., van Oostenbrugge, R. J., & Nagy, M. (2025). Association between coagulation activity and clinical and imaging outcomes in acute ischemic stroke patients - A sub-study of the MR CLEAN NO-IV trial. Thrombosis Research, 245, Article 109212. https://doi.org/10.1016/j.thromres.2024.109212
- Voorter, P. H. M., Stringer, M. S., van Dinther, M., Kerkhofs, D., Dewenter, A., Blair, G. W., Thrippleton, M. J., Jaime Garcia, D., Chappell, F. M., Janssen, E., Kopczak, A., Staals, J., Ingrisch, M., Duering, M., Doubal, F. N., Dichgans, M., van Oostenbrugge, R. J., Jansen, J. F. A., Wardlaw, J. M., ... SVDs@target Consortium (2025). Heterogeneity and Penumbra of White Matter Hyperintensities in Small Vessel Diseases Determined by Quantitative MRI. Stroke, 56(1), 128-137. https://doi.org/10.1161/STROKEAHA.124.047910
- Bink, D. I., Ritz, K., Mackaaij, C., Stam, O., Scheffer, S., Mizee, M. R., Ploegmakers, H. J., van Het Hof, B. J., de Boer, O. J., Sluimer, J., De Meyer, G. R., van der Weerd, L., de Vries, H. E., & Daemen, M. J. (2025). Lack of intracranial atherosclerosis in various atherosclerotic mouse models. Vascular Biology, 7(1), Article e230013. https://doi.org/10.1530/VB-23-0013
- Kök, M., Bokkers, R. P. H., Dippel, D. W. J., van der Lugt, A., van Doormaal, P. J., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., Zeebregts, C. J., & Uyttenboogaart, M. (2025). Use of a Balloon Guide Catheter during Endovascular Treatment of Acute Ischaemic Stroke due to Large Vessel Occlusion in the Anterior Circulation in Patients with an Atherosclerotic Tandem Lesion. European Journal of Vascular and Endovascular Surgery. Advance online publication. https://doi.org/10.1016/j.ejvs.2025.10.044
- Manukjan, N., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2025). Vascular endothelial growth factor: a double-edged sword in the development of white matter lesions. Neural Regeneration Research, 20(1), 191-192. https://doi.org/10.4103/NRR.NRR-D-23-01843
- Bleckwehl, T., Babler, A., Tebens, M., Maryam, S., Nyberg, M., Bosteen, M., Halder, M., Shaw, I., Fleig, S., Pyke, C., Hvid, H., Voetmann, L. M., van Buul, J. D., Sluimer, J. C., Das, V., Baumgart, S., Kramann, R., & Hayat, S. (2025). Encompassing view of spatial and single-cell RNA sequencing renews the role of the microvasculature in human atherosclerosis. Nature cardiovascular research, 4(1), 26-44. https://doi.org/10.1038/s44161-024-00582-1
- Nogueira, R. G., Jovin, T. G., Liu, X., Hu, W., Langezaal, L. C. M., Li, C., Dai, Q., Tao, C., Mont'Alverne, F. J. A., Ji, X., Liu, R., Li, R., Dippel, D. W. J., Wu, C., Zhu, W., Xu, P., van Zwam, W. H., Wu, L., Zhang, C., ... ATTENTION, BASICS, BAOCHE, and BEST Investigators (2025). Endovascular therapy for acute vertebrobasilar occlusion (VERITAS): a systematic review and individual patient data meta-analysis. Lancet, 405(10472), 61-69. https://doi.org/10.1016/S0140-6736(24)01820-8
- van Zwam, W. H., Aguiar de Sousa, D., & Ribo, M. (2025). ESR Bridges: imaging and treatment of cerebral ischaemia-a multidisciplinary view. European Radiology, 35(1), 1-3. https://doi.org/10.1007/s00330-024-10891-5
- Brown, S. D., Klimi, E., Bakker, W. A. M., Beqqali, A., & Baker, A. H. (2025). Non-coding RNAs to treat vascular smooth muscle cell dysfunction. British Journal of Pharmacology, 182(2), 246-280. https://doi.org/10.1111/bph.16409
- Lee, A., Jere, A., Du Plessis, L., Van Gerven, P. W. M., Heeneman, S., & Ross, S. (2025). Continuity of supervision: Balancing continuous and episodic relationships for assessment and learning. Medical Education, 59(6), 596-605. https://doi.org/10.1111/medu.15595
- van Mourik, H., Westheim, A., Schneider, C. V., Stoffels, L., Wieczerzak, E., Steeghs, J., Schneider, K. M., Temmerman, L., Biessen, E., Godschalk, R., Theys, J., & Shiri - Sverdlov, R. (2025). Extracellular Cathepsin B Is a potential Therapeutic Target in Hepatocellular Carcinoma. Liver International, 6(1), Article e70016. https://doi.org/10.1002/lci2.70016
- van Poppel, L. M., de Vries, L., Mojtahedi, M., Kappelhof, M., Olthuis, S. G. H., van Oostenbrugge, R., van Zwam, W. H., van Doormaal, P. J., Beenen, L. F. M., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Marquering, H. A., & Emmer, B. J. (2025). Machine learning models for CT-based classification of ischemic stroke onset time within or beyond 4.5 h: a comparison of approaches. European Radiology. Advance online publication. https://doi.org/10.1007/s00330-025-12189-6
- Kishna, Y. S., Robba, C., Van Der Horst, I. C. C., Taccone, F. S., Brasil, S., Bogli, S. Y., Zeiler, F. A., Mess, W. H., & Aries, M. (2025). Practicalities of noninvasive neuromonitoring in intensive care. Neurocritical Care. Advance online publication. https://doi.org/10.1007/s12028-025-02405-y
- 2024
- van Loon, T., Rijks, J., van Koll, J., Wolffs, J., Cornelussen, R., van Osta, N., Luermans, J., Prinzen, F., Linz, D., van Empel, V., Delhaas, T., Vernooy, K., & Lumens, J. (2024). Accelerated atrial pacing reduces left-heart filling pressure: a combined clinical-computational study. European Heart Journal, 45(46), 4953-4964. https://doi.org/10.1093/eurheartj/ehae718
- Sikking, M. A., Harding, D., Henkens, M. T. H. M., Stroeks, S. L. V. M., Venner, M. F. G. H. M., Nihant, B., van Leeuwen, R. E. W., Fanti, S., Li, X., van Paassen, P., Knackstedt, C., Brunner-la Rocca, H.-P., van Empel, V. P. M., Verdonschot, J. A. J., Marelli-Berg, F. M., & Heymans, S. R. B. (2024). Cytotoxic T-Cells Drive Outcome in Inflammatory Dilated Cardiomyopathy. Circulation Research, 135(12), 1193-1195. https://doi.org/10.1161/CIRCRESAHA.124.325183
- Robbe, M. M. Q., Pinckaers, F. M. E., Wagemans, B. A. J. M., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Additional value of CTP maps in occlusion detection on CTP angiographic reconstructions for ischemic stroke. European Journal of Radiology, 181, Article 111789. https://doi.org/10.1016/j.ejrad.2024.111789
- Robbe, M. M. Q., Pinckaers, F. M. E., Wagemans, B. A. J. M., van Oostenbrugge, R. J., van Zwam, W. H., Staals, J., & Postma, A. A. (2024). Angiographic reconstructions of CT perfusion for occlusion detection in ischemic stroke. European Journal of Radiology, 181, Article 111819. https://doi.org/10.1016/j.ejrad.2024.111819
- Ramaekers, M. J. F. G., Te Kiefte, B. J. C., Adriaans, B. P., Juffermans, J. F., van Assen, H. C., Winkens, B., Wildberger, J. E., Lamb, H. J., Schalla, S., & Westenberg, J. J. M. (2024). Comprehensive sex-specific and age-dependent analysis of four-dimensional flow cardiovascular magnetic resonance assessed aortic blood flow-related parameters in normal subjects using single-vendor magnetic resonance systems and single-vendor software. Journal of Cardiovascular Magnetic Resonance, 26(2), Article 101083. https://doi.org/10.1016/j.jocmr.2024.101083
- Devaux, Y., Zhang, L., Lumley, A. I., Karaduzovic-Hadziabdic, K., Mooser, V., Rousseau, S., Shoaib, M., Satagopam, V., Adilovic, M., Srivastava, P. K., Emanueli, C., Martelli, F., Greco, S., Badimon, L., Padro, T., Lustrek, M., Scholz, M., Rosolowski, M., Jordan, M., ... Firat, H. (2024). Development of a long noncoding RNA-based machine learning model to predict COVID-19 in-hospital mortality. Nature Communications, 15(1), Article 4259. https://doi.org/10.1038/s41467-024-47557-1
- Achten, A., Muller, S. A., Wijk, S. S., van der Meer, M. G., van der Harst, P., van Tintelen, P., Te Riele, A. S., van Empel, V., Oerlemans, M. I., & Knackstedt, C. (2024). Diversity of heart failure phenotypes in transthyretin amyloid cardiomyopathy. More than just heart failure with preserved ejection fraction. Annals of Medicine, 56(1), Article 2418965. https://doi.org/10.1080/07853890.2024.2418965
- Cozijnsen, L., Adriaans, B. P., Schermer, T. R., Groenink, M., Schalla, S., & Bekkers, S. C. A. M. (2024). Growth rates in non-syndromic aneurysms of the ascending aorta: a systematic review. Netherlands Heart Journal, 32(12), 433-441. https://doi.org/10.1007/s12471-024-01911-6
- Ekpenyong, A., Holmboe, E. S., Govaerts, M., & Heeneman, S. (2024). Investigating the Roles and Impact of Clinical Competency Committees in Graduate Medical Education: A Narrative Review. Journal of Graduate Medical Education, 16(6), 662-683. https://doi.org/10.4300/JGME-D-24-00017.1
- Jada, L., Holtackers, R. J., Martens, B., Nies, H. M. J. M., Van De Heyning, C. M., Botnar, R. M., Wildberger, J. E., Ismail, T. F., Razavi, R., & Chiribiri, A. (2024). Quantification of myocardial scar of different etiology using dark- and bright-blood late gadolinium enhancement cardiovascular magnetic resonance. Scientific Reports, 14(1), Article 5395. https://doi.org/10.1038/s41598-024-52058-8
- Fuentes-Cimma, J., Sluijsmans, D., Ortega-Bastidas, J., Villagran, I., Riquelme-Perez, A., & Heeneman, S. (2024). Students and Clinical Teachers’ Experiences About Productive Feedback Practices in the Clinical Workplace from a Sociocultural Perspective. International Medical Education, 3(4), 461-472. https://doi.org/10.3390/ime3040035
- Knapen, R. R. M. M., Celen, M., Benali, F., van Oostenbrugge, R. J., van Zwam, W. H., & van der Leij, C. (2024). The use of a (non-) balloon guide catheter in endovascular stroke treatment, a registry of real-life use and nationwide questionnaire. Journal of Stroke & Cerebrovascular Diseases, 33(12), Article 108033. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.108033
- van Nijnatten, T. J. A., de Mooij, C. M., Mitea, C., Houwers, J., de Boer, M., Smidt, M. L., Mottaghy, F. M., & Wildberger, J. E. (2024). [18F]FDG whole-body PET-MR including an integrated breast MR protocol for locoregional and distant staging in breast cancer patients-a feasibility study. Insights into Imaging, 15(1), Article 243. https://doi.org/10.1186/s13244-024-01830-5
- Bloch, M. J., Kirtane, A. J., Azizi, M., Mahfoud, F., Basile, J., Daemen, J., Saxena, M., Thackeray, L., McGuire, M., Claude, L., Schmieder, R. E., Kröpil, P., Stegbauer, J., Rump, C., Uder, M., Ott, C., Lucic, J., Ewen, S., Böhm, M., ... RADIANCE-HTN Investigators (2024). 36-month durability of ultrasound renal denervation for hypertension resistant to combination therapy in RADIANCE-HTN TRIO. Hypertension Research, 47(12), 3467-3472. https://doi.org/10.1038/s41440-024-01854-w
- Knapen, R. R. M. M., Olthuis, S. G. H., van Es, A. C. G. M., Emmer, B. J., Schonewille, W. J., van der Leij, C., van Zwam, W. H., van Oostenbrugge, R. J., & MR CLEAN LATE Trial investigators (2024). Association of first-line thrombectomy technique and outcome in late-window large vessel occlusion strokes: A post hoc analysis of the MR CLEAN-LATE trial. International journal of stroke, 19(10), 1113-1122. https://doi.org/10.1177/17474930241268303
- Strbian, D., Tsivgoulis, G., Ospel, J. M., Räty, S., Cimflova, P., Georgiopoulos, G., Ullberg, T., Arquizan, C., Gralla, J., Zelenák, K., Hussain, S., Fiehler, J., Michel, P., Turc, G., & van Zwam, W. (2024). European Stroke Organisation (ESO) and European Society for Minimally Invasive Neurological Therapy (ESMINT) Guideline on Acute Management of Basilar Artery Occlusion. European Stroke Journal, 9(4), 835-884. https://doi.org/10.1177/23969873241257223
- Berends, E., Pencheva, M. G., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., Hermes, D. J. H. P., Wouters, K., van Oostenbrugge, R. J., Foulquier, S., & Schalkwijk, C. G. (2024). Glyoxalase 1 overexpression improves neurovascular coupling and limits development of mild cognitive impairment in a mouse model of type 1 diabetes. Journal of Physiology, 602(22), 6209-6223. https://doi.org/10.1113/JP286723
- Kral, M., Doering, Y., & Weber, C. (2024). Early intermittent cholesterol exposure accelerates atherosclerosis: an oscillating amplifier calling for preemptive control. Signal Transduction and Targeted Therapy, 9(1), Article 313. https://doi.org/10.1038/s41392-024-02032-7
- Jesser, J., Nguyen, T., Dmytriw, A. A., Yamagami, H., Miao, Z., Sommer, L. J., Stockero, A., Pfaff, J. A. R., Ospel, J., Goyal, M., Patel, A. B., Pereira, V. M., Hanning, U., Meyer, L., van Zwam, W. H., Bendszus, M., Wiesmann, M., Möhlenbruch, M., & Weyland, C. S. (2024). Treatment practice of vasospasm during endovascular thrombectomy: an international survey. Stroke and Vascular Neurology, 9(5), 490-496. https://doi.org/10.1136/svn-2023-002788
- Tobal, R., Potjewijd, J., de Vries, F., van Doorn, D. P. C., Jaminon, A., Bittner, R., Akbulut, C., van Empel, V., Heeringa, P., Damoiseaux, J., Schurgers, L., & van Paassen, P. (2024). Dephosphorylated uncarboxylated Matrix-Gla-Protein as candidate biomarker for immune-mediated vascular remodeling and prognosis in pulmonary hypertension. Scientific Reports, 14(1), Article 26633. https://doi.org/10.1038/s41598-024-77000-w
- Jaspers, T. J. M., Martens, B., Crawley, R., Jada, L., Amirrajab, S., Breeuwer, M., Holtackers, R. J., Chiribiri, A., & Scannell, C. M. (2024). Deep Learning Synthesis of White-Blood From Dark-Blood Late Gadolinium Enhancement Cardiac Magnetic Resonance. Investigative Radiology, 59(11), 767-773. https://doi.org/10.1097/RLI.0000000000001086
- Robbe, M. M. Q., Pinckaers, F. M. E., van Kuijk, S. M. J., van Oostenbrugge, R. J., van Zwam, W. H., & Postma, A. A. (2024). Post-endovascular therapy contrast extravasation in the mesial temporal region on dual-energy CT is associated with outcome in acute ischemic stroke patients. Journal of Stroke & Cerebrovascular Diseases, 33(11), Article 107949. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107949
- Jauregui, J., McClintock, A. H., Schrepel, C., Fainstad, T., Bierer, S. B., & Heeneman, S. (2024). You Get What You Reward: A Qualitative Study Exploring Medical Student Engagement in 2 Different Assessment Systems. Academic Medicine, 99(11), 1278-1285. Article 10.1097/ACM.0000000000005848. https://doi.org/10.1097/ACM.0000000000005848
- Medina, I., Wieland, E. B., Temmerman, L., Otten, J. J. T., Bermudez, B., Bot, I., Rademakers, T., Wijnands, E., Schurgers, L., Mees, B., van Berkel, T. J. C., Goossens, P., & Biessen, E. A. L. (2024). Colony stimulating factor 1 receptor (Csf1r) expressing cell ablation in mafia (macrophage-specific Fas-induced apoptosis) mice alters monocyte landscape and atherosclerotic lesion characteristics. European Journal of Immunology, 54(11), Article 2350943. https://doi.org/10.1002/eji.202350943
- Zhao, D., Han, C., Mammadova-Bach, E., Watanabe-Kusunoki, K., Bandeira Honda, T. S., Li, Y., Li, C., Li, Q., Long, H., Lyubenov, L., Shi, C., Santovito, D., Weber, C., Boor, P., Droste, P., Parikh, S., Shapiro, J., De Chiara, L., Carangelo, G., ... Anders, H.-J. (2024). Inhibition of complement factor C5a or C5aR for cholesterol crystal embolism-related vascular thrombosis with microvascular injury and its consequences. Kidney International, 106(5), 819-825. https://doi.org/10.1016/j.kint.2024.07.020
- Nies, H. M. J. M., Linz, D., Bijvoet, G. P., Holtackers, R. J., Luermans, J. G. L. M., van der Velden, K. E. H. M., Wildberger, J. E., Vernooy, K., van Kuijk, S. M. J., Mihl, C., & Chaldoupi, S. M. (2024). Local atrial bipolar electrogram voltage drops during cardiac magnetic resonance guided catheter ablation of typical atrial flutter: Associations with delivered radiofrequency energy and peri-procedural imaging. Heart Rhythm O2, 5(11), 778-787. https://doi.org/10.1016/j.hroo.2024.08.015
- Döring, Y., van der Vorst, E. P. C., & Weber, C. (2024). Targeting immune cell recruitment in atherosclerosis. Nature reviews. Cardiology, 21(11), 824-840. https://doi.org/10.1038/s41569-024-01023-z
- Kral, M., van der Vorst, E. P. C., Weber, C., & Doering, Y. (2024). (Multi-) omics studies of ILC2s in inflammation and metabolic diseases. Frontiers in Cell and Developmental Biology, 12, Article 1473616. https://doi.org/10.3389/fcell.2024.1473616
- Mevenkamp, J., Bruls, Y. M. H., Mancilla, R., Grevendonk, L., Wildberger, J. E., Brouwers, K., Hesselink, M. K. C., Schrauwen, P., Hoeks, J., Houtkooper, R. H., Buitinga, M., de Graaf, R. A., Lindeboom, L., & Schrauwen-Hinderling, V. B. (2024). Development of a 31P magnetic resonance spectroscopy technique to quantify NADH and NAD+ at 3 T. Nature Communications, 15(1), Article 9159. https://doi.org/10.1038/s41467-024-53292-4



