Publications
- 2025
- Berghout, B. P., Fontana, F., Huijben, F., Korteland, S.-A., Kooi, M. E., Nederkoorn, P. J., de Jong, P. A., Gijsen, F. J., Pirola, S., Ikram, M. K., Bos, D., & Akyildiz, A. C. (2025). Morphometry of Intracranial Carotid Artery Calcifications in Patients with Recent Cerebral Ischemia. Journal of Clinical Medicine, 14(10), Article 3274. https://doi.org/10.3390/jcm14103274
- Saba, L., Cau, R., Vergallo, R., Kooi, M. E., Staub, D., Faa, G., Congiu, T., Ntaios, G., Wasserman, B. A., Benson, J., Nardi, V., Kawakami, R., Lanzino, G., Virmani, R., & Libby, P. (2025). Correction to: Carotid artery atherosclerosis: mechanisms of instability and clinical implications. European Heart Journal, 46(18), 1716. Article ehaf085. https://doi.org/10.1093/eurheartj/ehaf085
- Tziotziou, A., Fontana, F., Korteland, S.-A., Nies, K., Nederkoorn, P., de Jong, P. A., Kooi, M. E., van der Lugt, A., van der Steen, A. F. W., Wentzel, J. J., Bos, D., & Akyildiz, A. C. (2025). In-Depth Carotid Calcification Morphometrics and Their Temporal Changes Are Associated with Cardiovascular Risk Factors in Patients with Recent Ischemic Event: The Plaque At Risk Study. Cerebrovascular Diseases, 55(1), 10-20. https://doi.org/10.1159/000546164
- ECST 2 investigators (2025). Optimised medical therapy alone versus optimised medical therapy plus revascularisation for asymptomatic or low-to-intermediate risk symptomatic carotid stenosis (ECST-2): 2-year interim results of a multicentre randomised trial. Lancet Neurology, 24(5), 389-399. https://doi.org/10.1016/S1474-4422(25)00107-3
- Brown, S. D., Rodor, J., & Baker, A. H. (2025). Targeted approach for next-generation coronary stents. European Heart Journal, 46(17), 1659-1661. https://doi.org/10.1093/eurheartj/ehaf007
- Kassem, M., Gorissen, T., Albenwan, M., Bierens, J., van Dam-Nolen, D. H. K., Liem, M. I., Hofman, P. A. M., Wildberger, J. E., Hendrikse, J., Mess, W., Nederkoorn, P. J., Bos, D., Nelemans, P., van Oostenbrugge, R. J., & Kooi, M. E. (2025). The relationship between fibrous cap status or plaque surface morphology and intraplaque hemorrhage volume over time: The PARISK Study. Journal of Stroke & Cerebrovascular Diseases, 34(5), Article 108283. https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108283
- op den Kamp-bruls, Y. M. H., op den Kamp, Y. J. M., Veeraiah, P., Perez, R. Z., Phielix, E., Havekes, B., Schaart, G., Kornips, E., Berendsen, B. R. B., Virmani, A., Wildberger, J. E., Houtkooper, R. H., Hesselink, M. K. C., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2025). Carnitine supplementation improves insulin sensitivity and skeletal muscle acetylcarnitine formation in patients with type 2 diabetes. Diabetes Obesity & Metabolism, 27(5), 2864-2877. https://doi.org/10.1111/dom.16298
- Fuchs, C. J., Hermans, W. J. H., van den Hurk, J., Wiggins, C. J., Widholm, P., Dahlqvist Leinhard, O., Veeraiah, P., Wildberger, J. E., Prompers, J. J., & van Loon, L. J. C. (2025). Quantifying Leg Muscle Disuse Atrophy During Bed Rest Using DXA, CT, and MRI. European Journal of Sport Science, 25(5), Article e12299. https://doi.org/10.1002/ejsc.12299
- Chteinberg, E., Kolarova, J., Vogt, J., Macamo, A., Bormann, F., Kretzmer, H., Speel, E. J., van den Oord, J., Schneider, C., Stilgenbauer, S., Becker, J. C., Winnepenninckx, V., Biessen, E., Zenke, M., Kurz, A. K., Siebert, R., & zur Hausen, A. (2025). The significance of PAX5 in Merkel cell carcinoma. Journal of Pathology, 266(1), 81-94. https://doi.org/10.1002/path.6410
- Peters, L., Rakateli, L., Huchzermeier, R., Bonnin-Marquez, A., Maas, S. L., Lin, C., Jans, A., Geng, Y., Gorter, A., Gijbels, M., Rensen, S., Olinga, P., Hendrikx, T., Krawczyk, M., Brisbois, M., Jankowski, J., Bidzhekov, K., Weber, C., Biessen, E. A. L., ... van der Vorst, E. (2025). MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles. Elife, 13. https://doi.org/10.7554/eLife.97165
- Bierens, J., Severens-Rijvers, C., Hildebrand, S., van Zandvoort, M., Al-Nasiry, S., & Kapsokalyvas, D. (2025). Imaging and quantification of placental terminal villi microvasculature and nuclear characteristics in preeclampsia. European Journal of Obstetrics & Gynecology and Reproductive Biology, 308, 181-189. https://doi.org/10.1016/j.ejogrb.2025.03.015
- Psychogios, M., Brehm, A., Ribo, M., Rizzo, F., Strbian, D., Raety, S., Arenillas, J. F., Martinez-Galdamez, M., Hajdu, S. D., Michel, P., Gralla, J., Piechowiak, E. I., Kaiser, D. P. O., Puetz, V., van den Bergh, F., De Raedt, S., Bellante, F., Dusart, A., Hellstern, V., ... Staals, J. (2025). Endovascular Treatment for Stroke Due to Occlusion of Medium or Distal Vessels. New England Journal of Medicine, 392(14), 1374-1384. Article NEJMoa2408954. https://doi.org/10.1056/NEJMoa2408954
- Krilis, G., Beqqali, A., & Baker, A. H. (2025). ERC-funded Advanced Grant: creating molecular polypills. European Heart Journal, 46(14), 1288-1290. https://doi.org/10.1093/eurheartj/ehae866
- Sluis, W. M., Venema, S. M. U., van der Hoorn, A., Bot, J. C. J., van Zwam, W. H., Hofmeijer, J., & van der Worp, H. B. (2025). Endovascular treatment in comatose patients with anterior circulation ischemic stroke. Frontiers in Neurology, 16, Article 1524262. https://doi.org/10.3389/fneur.2025.1524262
- van der Vorst, E. P. C., & Lembo, G. (2025). Harnessing the power of the brain to fight metabolic diseases. Cardiovascular Research, 121(5), 685-687. https://doi.org/10.1093/cvr/cvaf061
- D'Italia, G., Schroen, B., & Cosemans, J. M. E. M. (2025). Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities. Esc heart failure, 12(2), 1013-1028. Article 15090. https://doi.org/10.1002/ehf2.15090
- Berends, E., Vangrieken, P., Amiri, N., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., Hermes, D. J. H. P., Wouters, K., van Oostenbrugge, R. J., Schalkwijk, C. G., & Foulquier, S. (2025). Increased Levels of Circulating Methylglyoxal Have No Consequence for Cerebral Microvascular Integrity and Cognitive Function in Young Healthy Mice. Molecular Neurobiology, 62(4), 4190-4202. Article 101148. https://doi.org/10.1007/s12035-024-04552-3
- Vermeulen, I., Li, M., van Mourik, H., Yadati, T., Eijkel, G., Balluff, B., Godschalk, R., Temmerman, L., Biessen, E. A. L., Kulkarni, A., Theys, J., Houben, T., Cillero-Pastor, B., & Shiri-Sverdlov, R. (2025). Inhibition of intracellular versus extracellular cathepsin D differentially alters the liver lipidome of mice with metabolic dysfunction-associated steatohepatitis. FEBS Journal, 292(7), 1781-1797. https://doi.org/10.1111/febs.17358
- Olthuis, S. G. H., & Van Zwam, W. H. (2025). Endovascular Therapy for NIHSS =5 How Low Should We Go?Neurology, 104(7), Article e213515. https://doi.org/10.1212/WNL.0000000000213515
- Saba, L., Cau, R., Vergallo, R., Kooi, M. E., Staub, D., Faa, G., Congiu, T., Ntaios, G., Wasserman, B. A., Benson, J., Nardi, V., Kawakami, R., Lanzino, G., Virmani, R., & Libby, P. (2025). Carotid artery atherosclerosis: mechanisms of instability and clinical implications. European Heart Journal, 46(10), 904-921. Article ehae933. https://doi.org/10.1093/eurheartj/ehae933
- McDonald, J., Hu, W., & Heeneman, S. (2025). Capturing meaningful moments: a narrative analysis of selfies in medical student portfolios. Journal of Learning Development in Higher Education, 2025(34). https://doi.org/10.47408/jldhe.vi34.1355
- Ben-Aicha, S., & van der Vorst, E. P. C. (2025). Shaping the future of cardiovascular research: a focus on cardioimmunology. European Heart Journal, 46(9), 778-780. Article ehae783. https://doi.org/10.1093/eurheartj/ehae783
- Frol, S., Benali, F., Rouchaud, A., Knapen, R. R. M. M., van Zwam, W. H., & Research Committee of the European Society of Minimally Invasive Neurological Therapy (ESMINT) (2025). The variable use of heparin through intravenous bolus and flush fluid systems during endovascular stroke treatment, a world-wide survey. CVIR Endovascular, 8(1), Article 17. https://doi.org/10.1186/s42155-025-00532-3
- Tore, E. C., Adriaans, B. C., Olsen, T., Vinknes, K. J., Kooi, M. E., Elshorbagy, A. K., Bastani, N. E., Dagnelie, P. C., Eussen, S. J. P. M., Gundersen, T. E., Kožich, V., Refsum, H., Retterstøl, K., Stolt, E. T. K., & van Greevenbroek, M. M. J. (2025). Estimated stearoyl-CoA desaturase activity mediates the associations of total cysteine with adiposity: The Maastricht Study. Journal of Clinical Lipidology, 19(2), 348-357. https://doi.org/10.1016/j.jacl.2024.11.005
- Lemmens, M.-J. D. K., Heuts, S., Bidar, E., Wildberger, J. E., Mihl, C., & Smulders, M. W. (2025). Integrating Coronary Artery Assessment and Myocardial Late Enhancement Imaging With Photon-Counting Detector CT: Visualizing the Invisible. Circulation-Cardiovascular Imaging, 18(3), e017238. Article e017238. https://doi.org/10.1161/CIRCIMAGING.124.017238
- Mentink, M. G., Latten, B. G. H., Bakers, F. C. H., Mihl, C., Hillen, L. M., & Hofman, P. A. M. (2025). Unveiling the diagnostic accuracy of PMCT: Detection of pneumonia considering postmortem changes and time intervals. Forensic imaging, 40, Article 200617. https://doi.org/10.1016/j.fri.2024.200617
- Taha, A., Nagy, M., Hund, H. M., van Doormaal, P. J., van Noorden, K., Spronk, H. M. H., Ceulemans, A., van Oostenbrugge, R. J., Duncker, D. J., ten Cate, H., Dippel, D., van Es, A. C. G. M., Bobi, J., & van Beusekom, H. M. M. (2025). Vascular injury and occurrence of microthrombi after endovascular therapy for acute ischaemic stroke in a thromboembolic model. BMJ Neurology Open, 7(1), Article e000989. https://doi.org/10.1136/bmjno-2024-000989
- Huchzermeier, R., & van der Vorst, E. P. C. (2025). Aryl hydrocarbon receptor (AHR) and nuclear factor erythroid-derived 2-like 2 (NRF2): An important crosstalk in the gut-liver axis. Biochemical Pharmacology, 233, Article 116785. https://doi.org/10.1016/j.bcp.2025.116785
- Stringer, M. S., Blair, G. W., Kopczak, A., Kerkhofs, D., Thrippleton, M. J., Chappell, F. M., Maniega, S. M., Brown, R., Shuler, K., Hamilton, I., Garcia, D. J., Doubal, F. N., Clancy, U., Sakka, E., Poliakova, T., Janssen, E., Duering, M., Ingrisch, M., Staals, J., ... Wardlaw, J. M. (2025). Cerebrovascular Function in Sporadic and Genetic Cerebral Small Vessel Disease. Annals of Neurology, 97(3), 483-498. https://doi.org/10.1002/ana.27136
- Voorter, P. H. M., Jansen, J. F. A., van der Thiel, M. M., van Dinther, M., Postma, A. A., van Oostenbrugge, R. J., Gurney-Champion, O. J., Drenthen, G. S., & Backes, W. H. (2025). Diffusion-derived intravoxel-incoherent motion anisotropy relates to CSF and blood flow. Magnetic Resonance in Medicine, 93(3), 930-941. https://doi.org/10.1002/mrm.30294
- Vacante, F., & Baker, A. H. (2025). Effective CRISPR modulation of complex non-coding RNA loci. Nature Reviews Cardiology, 22(3), 145. Article 145. https://doi.org/10.1038/s41569-025-01117-2
- Nagy, M., Bender, M., Poulter, N. S., Pike, J. A., Sickmann, A., Vondenhoff, S., Bielicka, N., van Zandvoort, M. A. M. J., Koenen, R. R., ten Cate, H., Stéphenne, X., Heemskerk, J. W. M., & Baaten, C. C. F. M. J. (2025). Formation of tight junction-like structures of zonula occludens 2 in platelet–platelet interaction. Research and practice in thrombosis and haemostasis, 9(3), Article 102845. https://doi.org/10.1016/j.rpth.2025.102845
- Halmos, B., La Rose, A. M., Methorst, D., Groenen, A. G., Nakládal, D., Bazioti, V., Koster, M. H., Kloosterhuis, N. J., Buiten, A. V., Schouten, E. M., Huijkman, N. C. A., Langelaar-Makkinje, M., Bongiovanni, L., De Neck, S. M., de Bruin, A., Buikema, H., Deelman, L. E., van den Heuvel, M. C., Kuipers, F., ... Westerterp, M. (2025). SMC Abca1 and Abcg1 Deficiency Enhances Urinary Bladder Distension but Not Atherosclerosis. Circulation Research, 136(5), 491-507. https://doi.org/10.1161/CIRCRESAHA.124.325103
- Fuentes-Cimma, J., Sluijsmans, D., Mejias, P. P., Villagran, I., Riquelme, A., & Heeneman, S. (2025). Psychometric properties of the Feedback Orientation Scale in the clinical workplace of health professions students. International Journal of Medical Education, 16, 36-44. https://doi.org/10.5116/ijme.679e.07de
- Vangrieken, P., Scheijen, J. L. J. M., Schiffers, P. M. H., van de Waarenburg, M. P. H., Foulquier, S., & Schalkwijk, C. C. G. (2025). Modelling the effects of elevated methylglyoxal levels on vascular and metabolic complications. Scientific Reports, 15(1), Article 6025. https://doi.org/10.1038/s41598-025-90661-5
- Hill, M. D., Goyal, M., Demchuk, A. M., Menon, B. K., Field, T. S., Guest, W. C., Berrouschot, J., Bormann, A., Pham, M., Haeusler, K. G., Dippel, D. W. J., van Doormaal, P. J., Dorn, F., Bode, F. J., van Adel, B. A., Sahlas, D. J., Swartz, R. H., Da Costa, L., Ospel, J. M., ... van Zwam, W. (2025). Efficacy and safety of nerinetide in acute ischaemic stroke in patients undergoing endovascular thrombectomy without previous thrombolysis (ESCAPE-NEXT): a multicentre, double-blind, randomised controlled trial. Lancet, 405(10478), 560-570. https://doi.org/10.1016/S0140-6736(25)00194-1
- Donker, E. M., van Rosse, F., Janssen, B. J. A., Knol, W., Dumont, G., van Smeden, J., Atiqi, R., Hessel, M., Richir, M. C., van Agtmael, M. A., Kramers, C., Tichelaar, J., & Education committee of the Dutch Society for Clinical Pharmacology and Biopharmacy (2025). Students' perspective on the Dutch National Pharmacotherapy Assessment, a national survey study among final-year medical students. European Journal of Pharmacology, 989, Article 177266. https://doi.org/10.1016/j.ejphar.2025.177266
- Donker, E. M., van Rosse, F., Janssen, B. J. A., Knol, W., Dumont, G., van Smeden, J., Atiqi, R., Hessel, M., Richir, M. C., van Agtmael, M. A., Kramers, C., Tichelaar, J., & Education committee of the Dutch Society for Clinical Pharmacology and Biopharmacy (2025). The impact of summative, formative or programmatic assessment on the Dutch National Pharmacotherapy Assessment: a retrospective multicentre study. European Journal of Pharmacology, 989, Article 177267. https://doi.org/10.1016/j.ejphar.2025.177267
- Rodor, J., Klimi, E., Brown, S. D., Krilis, G., Braga, L., Ring, N. A. R., Ballantyne, M. D., Kesidou, D., Dinh Cat, A. N., Miscianinov, V., Vacante, F., Miteva, K., Bennett, M., Beqqali, A., Giacca, M., Zacchigna, S., & Baker, A. H. (2025). Functional screening identifies miRNAs with a novel function inhibiting Vascular Smooth Muscle Cell proliferation. Molecular Therapy, 33(2), 615-630. https://doi.org/10.1016/j.ymthe.2024.12.037
- Hardy, J. C. A., Crombag, G. A. J. C., Peters, N. H. G. M., Hermsen, R., Willigers, J. L., Nobel, J. M., Wildberger, J. E., Flohr, T. G., & Postma, A. A. (2025). Bullet characterization using Photon-Counting detector CT: A phantom study with intact bullets. European Journal of Radiology, 183, Article 111898. https://doi.org/10.1016/j.ejrad.2024.111898
- Pinckaers, F. M. E., Grutters, J. P. C., Huijberts, I., Gabrio, A., Boogaarts, H. D., Postma, A. A., van Oostenbrugge, R. J., van Zwam, W. H., & Evers, S. M. A. A. (2025). Author's Response to Letter to the Editor Titled "Potential Biases in Post-stroke Health Utility Estimates by Modified Rankin Scale Scores". Value in Health, 28(2), 320-321. https://doi.org/10.1016/j.jval.2024.10.3854
- Arslan, M., Schaap, J., van Gorsel, B., Aubanell, A., Budde, R. P. J., Hirsch, A., Smulders, M. W., Mihl, C., Damman, P., Sliwicka, O., Habets, J., Dubois, E. A., & Dedic, A. (2025). Coronary computed tomography angiography improves assessment of patients with acute chest pain and inconclusively elevated high-sensitivity troponins. European Radiology, 35(2), 789-797. https://doi.org/10.1007/s00330-024-10930-1
- Gao, L., Churilov, L., Johns, H., Pujara, D., Hassan, A. E., Abraham, M., Ortega-Gutierrez, S., Hussain, M. S., Chen, M., Blackburn, S., Sitton, C. W., Pinckaers, F. M. E., van Zwam, W. H., Tsivgoulis, G., Hill, M. D., Grotta, J. C., Kasner, S., Ribo, M., Campbell, B. C., ... SELECT2 investigators (2025). Cost-Effectiveness of Endovascular Thrombectomy in Patients with Large Ischemic Stroke. Annals of Neurology, 97(2), 222-231. https://doi.org/10.1002/ana.27119
- Peeters, M. T. J., Postma, A. A., van Oostenbrugge, R. J., Henneman, W. J. P., & Staals, J. (2025). Dual-energy CT angiography in detecting underlying causes of intracerebral hemorrhage: an observational cohort study. Neuroradiology, 67(2), 331-338. https://doi.org/10.1007/s00234-024-03473-1
- van Oeteren, M. A. J., Simons, N., Simons, P. I. H. G., van de Waarenburg, M. P. H., Kooi, M. E., Feskens, E. J. M., van der Ploeg, E. M. C. L., Van den Eynde, M. D. G., Houben, A. J. H. M., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). Fructose restriction has beneficial effects on adipose tissue distribution but not on serum adipokine levels: Post-hoc analysis of a double-blind randomized controlled trial. Clinical Obesity, 15(1), Article e12714. https://doi.org/10.1111/cob.12714
- Ruthmann, F., Lo, J. W., Mendyk-Bordet, A.-M., Allart, E., Köhler, S., Klimkowicz-Mrowiec, A., Staals, J., Sachdev, P. S., Bordet, R., Dondaine, T., & Stroke and Cognition (STROKOG) Collaboration (2025). Prevalence of poststroke anxiety and its associations with global cognitive impairment: An individual participant data analysis. Journal of Affective Disorders, 369, 1136-1144. https://doi.org/10.1016/j.jad.2024.10.099
- Zhao, H., Xu, Z., Chen, L., Wu, L., Cui, Z., Ma, J., Sun, T., Lei, Y., Wang, N., Hu, H., Tan, Y., Lu, W., Yang, W., Liao, K., Teng, G., Liang, X., Li, Y., Feng, C., Nie, T., ... Zheng, C. (2025). Large-scale pretrained frame generative model enables real-time low-dose DSA imaging: An AI system development and multi-center validation study. Med, 6(1), Article 100497. https://doi.org/10.1016/j.medj.2024.07.025
- Baker, A. H., Giacca, M., & Thum, T. (2025). miRNA discovery to therapy: The field is sufficiently mature to assess the value of miRNA-based therapeutics. Molecular Therapy, 33(1), 3-4. https://doi.org/10.1016/j.ymthe.2024.12.024
- Ceulemans, A., Barakzie, A., Spronk, H. M. H., de Maat, M. P. M., van Beusekom, H. M. M., Taha, A., Emmer, B. J., Roos, Y. B. W. E. M., Dippel, D. W. J., Majoie, C. B. L. M., van Zwam, W. H., ten Cate, H., van Oostenbrugge, R. J., & Nagy, M. (2025). Association between coagulation activity and clinical and imaging outcomes in acute ischemic stroke patients - A sub-study of the MR CLEAN NO-IV trial. Thrombosis Research, 245, Article 109212. https://doi.org/10.1016/j.thromres.2024.109212



