Elschot, E. P., Backes, W. H., de Jong, J. J. A., Drenthen, G. S., Wong, S. M., Staals, J., Postma, A. A., Rouhl, R. P. W., van Oostenbrugge, R. J., & Jansen, J. F. A. (2023). Assessment of the clinical feasibility of detecting subtle blood-brain barrier leakage in cerebral small vessel disease using dynamic susceptibility contrast MRI. Magnetic Resonance Imaging, 102(1), 55-61. https://doi.org/10.1016/j.mri.2023.04.004

van Lanen, R. H. G. J., Haeren, R. H. L., Staals, J., Dings, J. T. A., Schijns, O. E. M. G., Hoogland, G., van Kuijk, S. M. J., Kapsokalyvas, D., van Zandvoort, M. A. M. J., Vink, H., Rijkers, K., & ACE Epilepsy Surgery Group (2023). Cerebrovascular glycocalyx damage and microcirculation impairment in patients with temporal lobe epilepsy. Journal of Cerebral Blood Flow and Metabolism, 43(10), 1737-1751. https://doi.org/10.1177/0271678X231179413

Giudici, A., van der Laan, K. W. F., van der Bruggen, M. M., Parikh, S., Berends, E., Foulquier, S., Delhaas, T., Reesink, K. D., & Spronck, B. (2023). Constituent-based quasi-linear viscoelasticity: a revised quasi-linear modelling framework to capture nonlinear viscoelasticity in arteries. Biomechanics and modeling in mechanobiology, 22(5), 1607–1623. https://doi.org/10.1007/s10237-023-01711-8

Voorter, P. H. M., Backes, W. H., Gurney-Champion, O. J., Wong, S.-M., Staals, J., van Oostenbrugge, R. J., van Der Thiel, M. M., Jansen, J. F. A., & Drenthen, G. S. (2023). Improving microstructural integrity, interstitial fluid, and blood microcirculation images from multi-b-value diffusion MRI using physics-informed neural networks in cerebrovascular disease. Magnetic Resonance in Medicine, 90(4), 1657 - 1671. https://doi.org/10.1002/mrm.29753

de Wit-Verheggen, V. H. W., Vanweert, F., Raiko, J., Liénard, V., Schaart, G., Gemmink, A., Nascimento, E. B. M., Hesselink, M. K. C., Wildberger, J. E., Wierts, R., Joris, P. J., Haas, J., Montaigne, D., Staels, B., Phielix, E., Schrauwen, P., Schrauwen-Hinderling, V. B., & van de Weijer, T. (2023). The tissue-specific metabolic effects of the PPARa agonist ciprofibrate in insulin-resistant male individuals: a double-blind, randomized, placebo-controlled crossover study. Obesity, 31(10), 2493-2504. https://doi.org/10.1002/oby.23874

van der Steen, W., van der Ende, N. A. M., Luijten, S. P. R., Rinkel, L. A., van Kranendonk, K. R., van Voorst, H., Roosendaal, S. D., Beenen, L. F. M., Coutinho, J. M., Emmer, B. J., van Oostenbrugge, R. J., Majoie, C. B. L. M., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Roozenbeek, B., MR CLEAN-NO IV Investigators, MR CLEAN-MED investigators, & CONTRAST Investigators (2023). Type of intracranial hemorrhage after endovascular stroke treatment: association with functional outcome. Journal of Neurointerventional Surgery, 15(10), 971-976. https://doi.org/10.1136/jnis-2022-019474

van der Weijden, J., De Hoogt, P. A., Leufkens, M. M. E., Keijbeck, A. A., van Goor, H., van den Heuvel, M. C., Cleutjens, J. P. M., Moers, C., Snoeijs, M. G., Navis, G. J., van Londen, M., Nolte, I. M., Berger, S. P., De Borst, M. H., & Peutz-Kootstra, C. J. (2023). The relationship of peritubular capillary density with glomerular volume and kidney function in living kidney donors. Journal of Nephrology, 36(7), 2111-2124. https://doi.org/10.1007/s40620-023-01734-5

Ruder, A., Wetzels, S. M. W., Temmerman, L., Biessen, E. A. L., & Goossens, P. (2023). Monocyte heterogeneity in cardiovascular disease. Cardiovascular Research, 119(11), 2033-2045. https://doi.org/10.1093/cvr/cvad069

Jeukens, C. R. L. P. N., Brauer, M. T. H., Mihl, C., Laupman, E., Nijssen, E. C., Wildberger, J. E., Martens, B., & van Pul, C. (2023). A New Algorithm for Automatically Calculating Noise, Spatial Resolution, and Contrast Image Quality Metrics: Proof-of-Concept and Agreement With Subjective Scores in Phantom and Clinical Abdominal CT. Investigative Radiology, 58(9), 649-655. https://doi.org/10.1097/RLI.0000000000000954

Kerstens, T. P., Weerts, J., van Dijk, A. P. J., Weijers, G., Knackstedt, C., Eijsvogels, T. M. H., Oxborough, D., van Empel, V. P. M., & Thijssen, D. H. J. (2023). Association of left ventricular strain-volume loop characteristics with adverse events in patients with heart failure with preserved ejection fraction. European Heart Journal Cardiovascular Imaging, 24(9), 1168-1176. https://doi.org/10.1093/ehjci/jead117

Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Abdul Hamid, M. A., Díez, J., Knackstedt, C., van Empel, V. P. M., Brunner-La Rocca, H. P., González, A., Wildberger, J. E., Heymans, S. R. B., & Hazebroek, M. R. (2023). Biomarkers of Collagen Metabolism Are Associated with Left Ventricular Function and Prognosis in Dilated Cardiomyopathy: A Multi-Modal Study. Journal of Clinical Medicine, 12(17), Article 5695. https://doi.org/10.3390/jcm12175695

Canto, E. D., van Deursen, L., Hoek, A. G., Elders, P. J. M., den Ruijter, H. M., van der Velden, J., van Empel, V., Serné, E. H., Eringa, E. C., & Beulens, J. W. J. (2023). Microvascular endothelial dysfunction in skin is associated with higher risk of heart failure with preserved ejection fraction in women with type 2 diabetes: the Hoorn Diabetes Care System Cohort. Cardiovascular Diabetology, 22(1), Article 234. https://doi.org/10.1186/s12933-023-01935-z

Alers, R.-J., Ghossein-Doha, C., Canjels, L. P. W., Muijtjens, E. S. H., Brandt, Y., Kooi, M. E., Gerretsen, S. C., Jansen, J. F. A., Backes, W. H., Hurks, P. P. M., van de Ven, V., & Spaanderman, M. E. A. (2023). Attenuated cognitive functioning decades after preeclampsia. American Journal of Obstetrics and Gynecology, 229(3), 294.e1-294.e14. https://doi.org/10.1016/j.ajog.2023.02.020

Rudilosso, S., Stringer, M. S., Thrippleton, M., Chappell, F., Blair, G. W., Garcia, D. J., Doubal, F., Hamilton, I., Janssen, E., Kopczak, A., Ingrisch, M., Kerkhofs, D., Backes, W. H., Staals, J., Duering, M., Dichgans, M., Wardlaw, J. M., & SVDs@Target Investigators (2023). Blood-brain barrier leakage hotspots collocating with brain lesions due to sporadic and monogenic small vessel disease. Journal of Cerebral Blood Flow and Metabolism, 43(9), 1490-1502. https://doi.org/10.1177/0271678X231173444

Huijberts, I., Pinckaers, F. M. E., van Zwam, W. H., Boogaarts, H. D., van Oostenbrugge, R. J., & Postma, A. A. (2023). Cerebral Arterial Air Emboli on Immediate Post-Endovascular Treatment CT are Associated with Poor Short- and Long-Term Clinical Outcomes in Acute Ischemic Stroke Patients. Journal of Neuroradiology, 50(5), 530-536. https://doi.org/10.1016/j.neurad.2023.06.001

Schaper, F. L. W. V. J., Nordberg, J., Cohen, A. L., Lin, C., Hsu, J., Horn, A., Ferguson, M. A., Siddiqi, S. H., Drew, W., Soussand, L., Winkler, A. M., Simo, M., Bruna, J., Rheims, S., Guenot, M., Bucci, M., Nummenmaa, L., Staals, J., Colon, A. J., ... Fox, M. D. (2023). Mapping Lesion-Related Epilepsy to a Human Brain Network. JAMA Neurology, 80(9), 891-902. https://doi.org/10.1001/jamaneurol.2023.1988

Exalto, L. G., Weaver, N. A., Kuijf, H. J., Aben, H. P., Bae, H.-J., Best, J. G., Bordet, R., Chen, C. P. L. H., van der Giessen, R. S., Godefroy, O., Gyanwali, B., Hamilton, O. K. L., Hilal, S., Huenges Wajer, I. M. C., Kim, J., Kappelle, L. J., Kim, B. J., Köhler, S., de Kort, P. L. M., ... Biessels, G. J. (2023). Sex Differences in Poststroke Cognitive Impairment: A Multicenter Study in 2343 Patients With Acute Ischemic Stroke. Stroke, 54(9), 2296-2303. https://doi.org/10.1161/STROKEAHA.123.042507

Wagner, J. U. G., Tombor, L. S., Malacarne, P. F., Kettenhausen, L. M., Panthel, J., Kujundzic, H., Manickam, N., Schmitz, K., Cipca, M., Stilz, K. A., Fischer, A., Muhly-Reinholz, M., Abplanalp, W. T., John, D., Mohanta, S. K., Weber, C., Habenicht, A. J. R., Buchmann, G. K., Angendohr, S., ... Dimmeler, S. (2023). Aging impairs the neurovascular interface in the heart. Science, 381(6660), 897-906. https://doi.org/10.1126/science.ade4961

Aydeniz, E., Weberndorfer, V., Brandts, L., Smulders, M. W., van Herpt, T. T. W., Martens, B., Vernooy, K., Linz, D., van der Horst, I. C. C., Wildberger, J. E., van Bussel, B. C. T., Driessen, R. G. H., & Mihl, C. (2023). Pericardial Fat Is Associated With Less Severe Multiorgan Failure Over Time in Patients With Coronavirus Disease-19: The Maastricht Intensive Care COVID Cohort. Journal of Thoracic Imaging. Advance online publication. https://doi.org/10.1097/RTI.0000000000000732

Kassem, M., Nies, K. P. H., Boswijk, E., van der Pol, J., Aizaz, M., Gijbels, M. J. J., Li, D., Bucerius, J., Mess, W. H., Wildberger, J. E., van Oostenbrugge, R. J., Moonen, R. P. M., Fan, Z., & Kooi, M. E. (2023). Quantification of carotid plaque composition with a multi-contrast atherosclerosis characterization (MATCH) MRI sequence. Frontiers in Cardiovascular Medicine, 10, Article 1227495. https://doi.org/10.3389/fcvm.2023.1227495

Sachs, S., Götz, A., Finan, B., Feuchtinger, A., DiMarchi, R. D., Döring, Y., Weber, C., Tschöp, M. H., Müller, T. D., & Hofmann, S. M. (2023). GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease. Cardiovascular Diabetology, 22(1), Article 217. https://doi.org/10.1186/s12933-023-01940-2

Jung, S. A., Malyaran, H., Demco, D. E., Manukanc, A., Häser, L. S., Kucikas, V., van Zandvoort, M., Neuss, S., & Pich, A. (2023). Fibrin-Dextran Hydrogels with Tunable Porosity and Mechanical Properties. Biomacromolecules, 24(9), 3972-3984. https://doi.org/10.1021/acs.biomac.3c00269

Manukjan, N., Majcher, D., Leenders, P., Caiment, F., van Herwijnen, M., Smeets, H. J. J., Suidgeest, E., van der Weerd, L., Vanmierlo, T., Jansen, J. F. A., Backes, W. H. H., van Oostenbrugge, R. J. J., Staals, J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment. Acta neuropathologica communications, 11(1), Article 128. https://doi.org/10.1186/s40478-023-01627-5

Maas, S., Jin, H., Lu, C., Nagenborg, J., Manca, M., Karel, J., Cavill, R., Sikkink, C., Yu, B., Nadeau, S., Dos Santos, J., Gijbels, M., Mees, B., Smirnov, E., Sluimer, J., Martins, G., Van der Vorst, E., & Biessen, E. (2023). Identification Of A Prdm1-Regulated T-Cell Network Which Controls T-Cell Driven Plaque Inflammation In Human And Mouse Atherosclerosis. Atherosclerosis, 379(S1), S11-S11. https://doi.org/10.1016/j.atherosclerosis.2023.06.914

Weber, C., Habenicht, A. J. R., & von Hundelshausen, P. (2023). Novel mechanisms and therapeutic targets in atherosclerosis: inflammation and beyond. European Heart Journal, 44(29), 2672-2681. https://doi.org/10.1093/eurheartj/ehad304

Ganizada, B. H., Reesink, K. D., Parikh, S., Ramaekers, M. J. F. G., Akbulut, A. C., Saraber, P. J. M. H., Debeij, G. P., Jaminon, A. M., Natour, E., Lorusso, R., Wildberger, J. E., Mees, B., Schurink, G. W., Jacobs, M. J., Cleutjens, J., Krapels, I., Gombert, A., Maessen, J. G., Accord, R., ... MUMC TAA Student Team (2023). The Maastricht Acquisition Platform for Studying Mechanisms of Cell-Matrix Crosstalk (MAPEX): An Interdisciplinary and Systems Approach towards Understanding Thoracic Aortic Disease. Biomedicines, 11(8), Article 2095. https://doi.org/10.3390/biomedicines11082095

You, W., Zhou, T., Knoops, K., Berendschot, T. T. J. M., van Zandvoort, M. A. M. J., Germeraad, W. T. V., Benedikter, B., Webers, C. A. B., Reutelingsperger, C. P. M., & Gorgels, T. G. M. F. (2023). Stressed neuronal cells can recover from profound membrane blebbing, nuclear condensation and mitochondrial fragmentation, but not from cytochrome c release. Scientific Reports, 13(1), Article 11045. https://doi.org/10.1038/s41598-023-38210-w

van Kuijk, K., McCracken, I. R., Tillie, R. J. H. A., Asselberghs, S. E. J., Kheder, D. A., Muitjens, S., Jin, H., Taylor, R. S., Schreur, R. W., Kuppe, C., Dobie, R., Ramachandran, P., Gijbels, M. J., Temmerman, L., Kirkwoord, P. M., Luyten, J., Li, Y. M., Noels, H., Goossens, P., ... Sluimer, J. C. (2023). Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol. Cardiovascular Research, 119(7), 1509-1523. https://doi.org/10.1093/cvr/cvad016

Ramaekers, M. J. F. G., Westenberg, J. J. M., Adriaans, B. P., Nijssen, E. C., Wildberger, J. E., Lamb, H. J., & Schalla, S. (2023). A clinician's guide to understanding aortic 4D flow MRI. Insights into Imaging, 14(1), Article 114. https://doi.org/10.1186/s13244-023-01458-x

Reiche, M. E., Poels, K., Bosmans, L. A., Vos, W. G., Van Tiel, C. M., Gijbels, M. J. J., Aarts, S. A. B. M., Den Toom, M., Beckers, L., Weber, C., Atzler, D., Rensen, P. C. N., Kooijman, S., & Lutgens, E. (2023). Adipocytes control hematopoiesis and inflammation through CD40 signaling. Haematologica-the Hematology Journal, 108(7), 1873-1885. https://doi.org/10.3324/haematol.2022.281482

Kerkhofs, D., Helgers, R., Hermes, D., Steinbusch, H. P. J., Van Essen, H., Leenders, P., Prickaerts, J., Staals, J., Biessen, E. A., Van Oostenbrugge, R. J., & Foulquier, S. (2023). Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice. Journal of Hypertension, 41(7), 1159-1167. https://doi.org/10.1097/HJH.0000000000003445

Knapen, R. R. M. M., Bernsen, M. L. E., Langezaal, L. C. M., Olthuis, S. G. H., Michel, P., Hofmeijer, J., Vos, J.-A., van Kuijk, S. M. J., Majoie, C. B., Emmer, B. J., Nijeholt, G. J. L. A., Boiten, J., Puetz, V., Gerber, J., Mazighi, M., Pontes-Neto, O. M., Mont'Alverne, F., Yoo, A. J., van Doormaal, P.-J., ... Schonewille, W. J. (2023). Aspiration Versus Stent Retriever Thrombectomy in Basilar-Artery Occlusion; Results From the BASICS Trial. Stroke: vascular and interventional neurology, 3(4), Article e000768. https://doi.org/10.1161/SVIN.122.000768

Parikh, S., Moerman, K. M., Ramaekers, M. J. F. G., Schalla, S., Bidar, E., Delhaas, T., Reesink, K., & Huberts, W. (2023). Biomechanical Characterisation of Thoracic Ascending Aorta with Preserved Pre-Stresses. Bioengineering, 10(7), Article 846. https://doi.org/10.3390/bioengineering10070846

Canjels, L. P. W., Alers, R. J., van de Ven, V., Hurks, P. P. M., Gerretsen, S. C., Brandt, Y., Kooi, M. E., Jansen, J. F. A., Backes, W. H., Ghossein-Doha, C., & Spaanderman, M. E. A. (2023). Cerebral volume is unaffected after pre-eclampsia. Ultrasound in Obstetrics & Gynecology, 62(1), 115-121. https://doi.org/10.1002/uog.26172

Blanchet, X., Weber, C., & von Hundelshausen, P. (2023). Chemokine Heteromers and Their Impact on Cellular Function-A Conceptual Framework. International Journal of Molecular Sciences, 24(13), Article 10925. https://doi.org/10.3390/ijms241310925

Soo, Y., Zietz, A., Yiu, B., Mok, V. C. T., Polymeris, A. A., Seiffge, D., Ambler, G., Wilson, D., Leung, T. W. H., Tsang, S. F., Chu, W., Abrigo, J., Cheng, C., Lee, K.-J., Lim, J.-S., Shiozawa, M., Koga, M., Chabriat, H., Hennerici, M., ... Peters, N. (2023). Impact of Cerebral Microbleeds in Stroke Patients with Atrial Fibrillation. Annals of Neurology, 94(1), 61-74. https://doi.org/10.1002/ana.26642

Duering, M., Biessels, G. J., Brodtmann, A., Chen, C., Cordonnier, C., de Leeuw, F.-E., Debette, S., Frayne, R., Jouvent, E., Rost, N. S., ter Telgte, A., Salman, R. A.-S., Backes, W. H., Bae, H.-J., Brown, R., Chabriat, H., De Luca, A., deCarli, C., Dewenter, A., ... Et al. (2023). Neuroimaging standards for research into small vessel disease-advances since 2013. Lancet Neurology, 22(7), 602-618. https://doi.org/10.1016/S1474-4422(23)00131-X

Wildberger, J. E. E., & Alkadhi, H. (2023). New Horizons in Vascular Imaging With Photon-Counting Detector CT. Investigative Radiology, 58(7), 499-504. https://doi.org/10.1097/RLI.0000000000000957

Sartoretti, T., Wildberger, J. E., Flohr, T., & Alkadhi, H. (2023). Photon- counting detector CT: early clinical experience review. British Journal of Radiology, 96(1147), Article 20220544. https://doi.org/10.1259/bjr.20220544

Colin, M., Delaitre, C., Foulquier, S., & Dupuis, F. (2023). The AT(1)/AT(2) Receptor Equilibrium Is a Cornerstone of the Regulation of the Renin Angiotensin System beyond the Cardiovascular System. Molecules, 28(14), Article 5481. https://doi.org/10.3390/molecules28145481

Lobbes, M. B. I., Neeter, L. M. F. H., Raat, F., Turk, K., Wildberger, J. E., van Nijnatten, T. J. A., & Nelemans, P. J. (2023). The performance of contrast-enhanced mammography and breast MRI in local preoperative staging of invasive lobular breast cancer. European Journal of Radiology, 164(1), Article 110881. https://doi.org/10.1016/j.ejrad.2023.110881

Naothavorn, W., Puranitee, P., Kaewpila, W., Sumrithe, S., Heeneman, S., van Mook, W. N. K. A., & Busari, J. O. (2023). An exploratory university-based cross-sectional study of the prevalence and reporting of mistreatment and student-related factors among Thai medical students. BMC Medical Education, 23(1), Article 473. https://doi.org/10.1186/s12909-023-04462-3

Lo, J. W., Crawford, J. D., Desmond, D. W., Bae, H. J., Lim, J. S., Godefroy, O., Roussel, M., Köhler, S., Staals, J., Verhey, F., Chen, C., Xu, X., Chong, E. J., Kandiah, N., Bordet, R., Dondaine, T., Mendyk, A. M., Brodaty, H., Traykov, L., ... Sachdev, P. S. (2023). Short-term Trajectories of Poststroke Cognitive Function: A STROKOG Collaboration Study. Neurology, 100(23), E2331-E2341. https://doi.org/10.1212/WNL.0000000000207281

Chemaly, M., Marlevi, D., Iglesias, M.-J., Lengquist, M., Kronqvist, M., Bos, D., van Dam-Nolen, D. H. K., van der Kolk, A., Hendrikse, J., Kassem, M., Matic, L., Odeberg, J., de Vries, M. R., Kooi, M. E., & Hedin, U. (2023). Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Patients with Symptomatic Carotid Atherosclerosis. Biomolecules, 13(6), Article 882. https://doi.org/10.3390/biom13060882

Skenteris, N. T., Hemme, E., Delfos, L., Karadimou, G., Karlof, E., Lengquist, M., Kronqvist, M., Zhang, X., Maegdefessel, L., Schurgers, L. J., Arnardottir, H., Biessen, E. A. L., Bot, I., & Matic, L. (2023). Mast cells participate in smooth muscle cell reprogramming and atherosclerotic plaque calcification. Vascular Pharmacology, 150(1), Article 107167. https://doi.org/10.1016/j.vph.2023.107167

Terreros, N. A., Renon, S., Zucchelli, F., Bridio, S., Matas, J. F. R., Dubini, G., Konduri, P. R., Koopman, M. S., Zwam, W. H. V., Yo, L. S. F., Lo, R. H., Marquering, H. A., van Bavel, E., Majoie, C. B. L. M., Migliavacca, F., & Luraghi, G. (2023). Microcatheter tracking in thrombectomy procedures: A finite-element simulation study. Computer Methods and Programs in Biomedicine, 234(1), Article 107515. https://doi.org/10.1016/j.cmpb.2023.107515

Nies, H. M. J. M., Martens, B., Gommers, S., Bijvoet, G. P., Wildberger, J. E., Ter Bekke, R. M. A., Holtackers, R. J., & Mihl, C. (2023). Myocardial Scar Detection Using High-Resolution Free-Breathing 3D Dark-Blood and Standard Breath-Holding 2D Bright-Blood Late Gadolinium Enhancement MRI: A Comparison of Observer Confidence. Topics in Magnetic Resonance Imaging, 32(3), 27-32. https://doi.org/10.1097/RMR.0000000000000304

Farina, F. M., Weber, C., & Santovito, D. (2023). The emerging landscape of non-conventional RNA functions in atherosclerosis. Atherosclerosis, 374(1), 74-86. https://doi.org/10.1016/j.atherosclerosis.2023.01.009

van den Berg, L. A., Berkhemer, O., Fransen, P. S. S., Beumer, D., Majoie, C. B. L., Dippel, D. W. J., van der Lugt, A. J., van Oostenbrugge, R. H., van Zwam, W. B., Roos, Y., Dijkgraaf, M. G. W., & MR CLEAN Investigators (2023). Budget impact of endovascular treatment for acute ischaemic stroke patients in the Netherlands for 2015-2021. Netherlands Heart Journal, 31(6), 254-259. https://doi.org/10.1007/s12471-023-01788-x

Pinckaers, F. M., Mentink, M. M., Boogaarts, H. D., van Zwam, W. H., van Oostenbrugge, R. J., & Postma, A. A. (2023). Early post-endovascular treatment contrast extravasation on dual-energy CT is associated with clinical and radiological stroke outcomes: A 10-year single-centre experience. European Stroke Journal, 8(2), 508-516. https://doi.org/10.1177/23969873231157901