• 2018
    • Tullemans, B. M. E., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2018). Acquired platelet antagonism: off-target antiplatelet effects of malignancy treatment with tyrosine kinase inhibitors. Journal of Thrombosis and Haemostasis, 16(9), 1686-1699. https://doi.org/10.1111/jth.14225
    • Stifft, F., van Kuijk, S. M. J., Bekers, O., & Christiaans, M. H. L. (2018). Increase in tacrolimus exposure after steroid tapering is influenced by CYP3A5 and pregnane X receptor genetic polymorphisms in renal transplant recipients. Nephrology Dialysis Transplantation, 33(9), 1668-1675. https://doi.org/10.1093/ndt/gfy096
    • ten Cate, H. (2018). Testing direct oral anticoagulants: embedding in structured long-term care. Blood Transfusion, 16(5), 410-412. https://doi.org/10.2450/2017.0197-17
    • Baaten, C. C. F. M. J., Moenen, F. C. J. I., Henskens, Y. M. C., Swieringa, F., Wetzels, R. J. H., van Oerle, R., Heijnen, H. F. G., ten Cate, H., Holloway, G. P., Beckers, E. A. M., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2018). Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy. Haematologica-the Hematology Journal, 103(9), 1557-1567. https://doi.org/10.3324/haematol.2017.185165
    • Dickhout, A., & Koenen, R. R. (2018). Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks. Frontiers in Cardiovascular Medicine, 5, Article 113. https://doi.org/10.3389/fcvm.2018.00113
    • Schelpe, A.-S., Orlando, C., Ercig, B., Geeroms, C., Pareyn, I., Vandeputte, N., Pereira, L. C., Roose, E., Fostier, K., Nicolaes, G. A. F., Deckmyn, H., De Meyer, S. F., Vanhoorelbeke, K., & Jochmans, K. (2018). Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13. European Journal of Haematology, 101(2), 191-199. https://doi.org/10.1111/ejh.13094
    • Amin, E. E., Joore, M. A., ten Cate, H., Meijer, K., Tick, L. W., Middeldorp, S., Mostard, G. J. M., ten Wolde, M., Van den Heiligenberg, S. M., Van Wissen, S., Van de Poel, M. H. W., Villalta, S., Serne, E. H., Otten, H.-M., Klappe, E. H., Prandoni, P., & ten Cate-Hoek, A. J. (2018). Clinical and economic impact of compression in the acute phase of deep vein thrombosis. Journal of Thrombosis and Haemostasis, 16(8), 1555-1563. https://doi.org/10.1111/jth.14163
    • Crombag, G. A. J. C., Spronk, H. M., Nelemans, P., Schreuder, F. H. B. M., Truijman, M. T. B., van Dijk, A. C., de Rotte, A. A. J., Liem, M. I., Daemen, M. J. A. P., van der Steen, A. F. W., Mess, W. H., Nederkoorn, P. J., Hendrikse, J., van der Lugt, A., Wildberger, J. E., ten Cate, H., van Oostenbrugge, R. J., & Kooi, M. E. (2018). No Association between Thrombin Generation and Intra-Plaque Haemorrhage in Symptomatic Carotid Atherosclerotic Plaques: The Plaque at RISK (PARISK) Study. Thrombosis and Haemostasis, 118(8), 1461-1469. https://doi.org/10.1055/s-0038-1666858
    • Kremers, B. M. M., Ten Cate, H., & Spronk, H. M. H. (2018). Pleiotropic effects of the hemostatic system. Journal of Thrombosis and Haemostasis, 16(8), 1464-1473. https://doi.org/10.1111/jth.14161
    • Witten, A., Bolbrinker, J., Barysenka, A., Huber, M., Ruhle, F., Nowak-Gottl, U., Garbe, E., Kreutz, R., & Stoll, M. (2018). Targeted resequencing of a locus for heparin-induced thrombocytopenia on chromosome 5 identified in a genome-wide association study. Journal of Molecular Medicine, 96(8), 765-775. https://doi.org/10.1007/s00109-018-1661-6
    • D'Alessandro, E., Posma, J. J. N., Spronk, H. M. H., & ten Cate, H. (2018). Tissue factor (:Factor VIIa) in the heart and vasculature: More than an envelope. Thrombosis Research, 168, 130-137. https://doi.org/10.1016/j.thromres.2018.06.020
    • Veugen, M. G. J., Henry, R. M. A., Brunner-La Rocca, H.-P., Dagnelie, P. C., Schram, M. T., van Agtmaal, M. J. M., van der Kallen, C. J. H., Sep, S. J. S., van Boxtel, M. P. J., Bekers, O., Meex, S. J. R., Jansen, J. F. A., Kroon, A. A., & Stehouwer, C. D. A. (2018). Cross-sectional associations between cardiac biomarkers, cognitive performance, and structural brain changes are modified by age: The Maastricht Study. Arteriosclerosis Thrombosis and Vascular Biology, 38(8), 1948-1958. https://doi.org/10.1161/ATVBAHA.118.311082
    • van Setten, J., Brody, J. A., Jamshidi, Y., Swenson, B. R., Butler, A. M., Campbell, H., Del Greco, F. M., Evans, D. S., Gibson, Q., Gudbjartsson, D. F., Kerr, K. F., Krijthe, B. P., Lyytikainen, L.-P., Muller, C., Muller-Nurasyid, M., Nolte, I. M., Padmanabhan, S., Ritchie, M. D., Robino, A., ... Sotoodehnia, N. (2018). PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications, 9, Article 2904. https://doi.org/10.1038/s41467-018-04766-9
    • Peeters, F. E. C. M., Meex, S. J. R., Dweck, M. R., Aikawa, E., Crijns, H. J. G. M., Schurgers, L. J., & Kietselaer, B. L. J. H. (2018). Calcific aortic valve stenosis: hard disease in the heart. European Heart Journal, 39(28), 2618–2624. https://doi.org/10.1093/eurheartj/ehx653
    • Vroemen, W. H. M., de Boer, D., Streng, A. S., Mingels, A. M. A., & Meex, S. J. R. (2018). Elevated Cardiac Troponin T in Skeletal Myopathies: Skeletal TnT Cross-Reactivity and/or Cardiac TnT Expression?Journal of the American College of Cardiology, 72(3), 347-349. https://doi.org/10.1016/j.jacc.2018.05.017
    • Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., ... Jamshidi, Y. (2018). Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. Genome Biology, 19, Article 87. https://doi.org/10.1186/s13059-018-1457-6
    • Vajen, T., Koenen, R. R., Werner, I., Staudt, M., Projahn, D., Curaj, A., Sonmez, T. T., Simsekyilmaz, S., Schumacher, D., Mollmann, J., Hackeng, T. M., von Hundelshausen, P., Weber, C., & Liehn, E. A. (2018). Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis. Scientific Reports, 8, Article 10647. https://doi.org/10.1038/s41598-018-29026-0
    • Whitworth, J., Smith, P. S., Martin, J.-E., West, H., Luchetti, A., Rodger, F., Clark, G., Carss, K., Stephens, J., Stirrups, K., Penkett, C., Mapeta, R., Ashford, S., Megy, K., Shakeel, H., Ahmed, M., Adlard, J., Barwell, J., Brewer, C., ... NIHR BioResource Rare Diseases Consortium (2018). Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. American Journal of Human Genetics, 103(1), 3-18. https://doi.org/10.1016/j.ajhg.2018.04.013
    • Ito, Y., Carss, K. J., Duarte, S. T., Hartley, T., Keren, B., Kurian, M. A., Marey, I., Charles, P., Mendonca, C., Nava, C., Pfundt, R., Sanchis-Juan, A., van Bokhoven, H., van Essen, A., van Ravenswaaij-Arts, C., Boycott, K. M., Kernohan, K. D., Dyack, S., Raymond, F. L., ... Care4Rare Canada Consortium (2018). De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures. American Journal of Human Genetics, 103(1), 144-153. https://doi.org/10.1016/j.ajhg.2018.06.001
    • Winter, C., Silvestre-Roig, C., Ortega-Gomez, A., Lemnitzer, P., Poelman, H., Schumski, A., Winter, J., Drechsler, M., de Jong, R., Immler, R., Sperandio, M., Hristov, M., Zeller, T., Nicolaes, G. A. F., Weber, C., Viola, J. R., Hidalgo, A., Scheiermann, C., & Soehnlein, O. (2018). Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metabolism, 28(1), 175-182.e5. https://doi.org/10.1016/j.cmet.2018.05.002
    • Amin, E. E., van Kuijk, S. M. J., Joore, M. A., Prandoni, P., ten Cate, H., & ten Cate-Hoek, A. J. (2018). Development and Validation of a Practical Two-Step Prediction Model and Clinical Risk Score for Post-Thrombotic Syndrome. Thrombosis and Haemostasis, 118(7), 1242-1249. https://doi.org/10.1055/s-0038-1655743
    • van Doorn, P., Rosing, J., Duckers, C., Hackeng, T. M., Simioni, P., & Castoldi, E. (2018). Factor V Has Anticoagulant Activity in Plasma in the Presence of TFPI: Difference between FV1 and FV2. Thrombosis and Haemostasis, 118(7), 1194-1202. https://doi.org/10.1055/s-0038-1656549
    • Moenen, F. C. J. I., Nelemans, P. J., Schols, S. E. M., Schouten, H. C., Henskens, Y. M. C., & Beckers, E. A. M. (2018). The diagnostic accuracy of bleeding assessment tools for the identification of patients with mild bleeding disorders: A systematic review. Haemophilia, 24(4), 525-535. https://doi.org/10.1111/hae.13486
    • Swieringa, F., Spronk, H. M. H., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2018). Integrating platelet and coagulation activation in fibrin clot formation. Research and practice in thrombosis and haemostasis, 2(3), 450-460. https://doi.org/10.1002/rth2.12107
    • Kimenai, D. M., Janssen, E. B. N. J., Eggers, K. M., Lindahl, B., den Ruijter, H. M., Bekers, O., Appelman, Y., & Meex, S. J. R. (2018). Sex-Specific Versus Overall Clinical Decision Limits for Cardiac Troponin I and T for the Diagnosis of Acute Myocardial Infarction: A Systematic Review. Clinical Chemistry, 64(7), 1034-1043. https://doi.org/10.1373/clinchem.2018.286781
    • Vaidya, A., Kleinegris, M.-C., Severens, J. L., Ramaekers, B. L., ten Cate-Hoek, A. J., ten Cate, H., & Joore, M. A. (2018). Comparison of EQ-5D and SF-36 in untreated patients with symptoms of intermittent claudication. Journal of Comparative Effectiveness Research, 7(6), 535-548. https://doi.org/10.2217/cer-2017-0029
    • van Bussel, B. C. T., Henry, R. M. A., Schalkwijk, C. G., Dekker, J. M., Nijpels, G., Feskens, E. J. M., & Stehouwer, C. D. A. (2018). Alcohol and red wine consumption, but not fruit, vegetables, fish or dairy products, are associated with less endothelial dysfunction and less low-grade inflammation: the Hoorn Study. European Journal of Nutrition, 57(4), 1409-1419. https://doi.org/10.1007/s00394-017-1420-4
    • Panova-Noeva, M., Schulz, A., Spronk, H. M., Beicht, A., Laubert-Reh, D., van Oerle, R., Arnold, N., Prochaska, J. H., Blettner, M., Beutel, M., Pfeiffer, N., Munzel, T., Lackner, K. J., ten Cate, H., & Wild, P. S. (2018). Clinical Determinants of Thrombin Generation Measured in Presence and Absence of Platelets-Results from the Gutenberg Health Study. Thrombosis and Haemostasis, 118(5), 873-882. https://doi.org/10.1055/s-0038-1641565
    • Lin, H., van Setten, J., Smith, A. V., Bihlmeyer, N. A., Warren, H. R., Brody, J. A., Radmanesh, F., Hall, L., Grarup, N., Muller-Nurasyid, M., Boutin, T., Verweij, N., Lin, H. J., Li-Gao, R., van den Berg, M. E., Marten, J., Weiss, S., Prins, B. P., Haessler, J., ... Isaacs, A. (2018). Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval. Circulation: Genomic and Precision Medicine, 11(5), Article e002037 . https://doi.org/10.1161/CIRCGEN.117.002037
    • ten Cate, H., Olie, R. H., ten Cate-Hoek, A. J., & Henskens, Y. M. C. (2018). Direct oral anticoagulants: When to consider laboratory testing?International Journal of Laboratory Hematology, 40(S1), 30-33. https://doi.org/10.1111/ijlh.12816
    • De Maertelaere, E., Castoldi, E., Van Haute, I., Deeren, D., & Devreese, K. M. (2018). The interaction of factor V and tissue factor pathway inhibitor in a myeloma patient with acquired factor V deficiency. Haemophilia, 24(3), E160-E163. https://doi.org/10.1111/hae.13492
    • Hilderink, J. M., van der Linden, N., Kimenai, D. M., Litjens, E. J. R., Klinkenberg, L. J. J., Aref, B. M., Aziz, F., Kooman, J. P., Rennenberg, R. J. M. W., Bekers, O., Koopmans, R. P., & Meex, S. J. R. (2018). Biological Variation of Creatinine, Cystatin C, and eGFR over 24 Hours. Clinical Chemistry, 64(5), 851-860. https://doi.org/10.1373/clinchem.2017.282517
    • Streng, A., van der Linden, N., Kocken, J. M. M., Bekers, O., Bouwman, F., Mariman, E., Meex, S., Wodzig, W., & de Boer, D. (2018). Mass Spectrometric Identification of Cardiac Troponin T in Urine of Patients Suffering from Acute Myocardial Infarction. Journal of Applied Laboratory Medicine, 2(6), 857-867. https://doi.org/10.1373/jalm.2017.024224
    • Sabrkhany, S., Kuijpers, M. J. E., Knol, J. C., Damink, S. W. M. O., Dingemans, A.-M. C., Verheul, H. M., Piersma, S. R., Pham, T. V., Griffioen, A. W., Egbrink, M. G. A. O., & Jimenez, C. R. (2018). Exploration of the platelet proteome in patients with early-stage cancer. Journal of Proteomics, 177, 65-74. https://doi.org/10.1016/j.jprot.2018.02.011
    • Schurgers, L. J., Akbulut, A. C., Kaczor, D. M., Halder, M., Koenen, R. R., & Kramann, R. (2018). Initiation and Propagation of Vascular Calcification Is Regulated by a Concert of Platelet- and Smooth Muscle Cell-Derived Extracellular Vesicles. Frontiers in Cardiovascular Medicine, 5, Article 36. https://doi.org/10.3389/fcvm.2018.00036
    • Peeters, F. E. C. M., van Mourik, M. J. W., Meex, S. J. R., Bucerius, J., Schalla, S. M., Gerretsen, S. C., Mihl, C., Dweck, M. R., Schurgers, L. J., Wildberger, J. E., Crijns, H. J. G. M., & Kietselaer, B. L. J. H. (2018). Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using F-18-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design. Nutrients, 10(4), Article 386. https://doi.org/10.3390/nu10040386
    • Panova-Noeva, M., Schulz, A., Arnold, N., Hermanns, M. I., Prochaska, J. H., Laubert-Reh, D., Spronk, H. M., Blettner, M., Beutel, M., Pfeiffer, N., Munzel, T., Lackner, K. J., ten Cate, H., & Wild, P. S. (2018). Coagulation and inflammation in long-term cancer survivors: results from the adult population. Journal of Thrombosis and Haemostasis, 16(4), 699-708. https://doi.org/10.1111/jth.13975
    • Mackman, N., Spronk, H. M. H., Stouffer, G. A., & ten Cate, H. (2018). Dual Anticoagulant and Antiplatelet Therapy for Coronary Artery Disease and Peripheral Artery Disease Patients. Arteriosclerosis Thrombosis and Vascular Biology, 38(4), 726-732. https://doi.org/10.1161/ATVBAHA.117.310048
    • Vajen, T., Heinzmann, A. C. A., Dickhout, A., Zhao, Z., Nagy, M., Heemskerk, J. W. M., & Koenen, R. R. (2018). Laminar Flow-based Assays to Investigate Leukocyte Recruitment on Cultured Vascular Cells and Adherent Platelets. Journal of visualized experiment, (134), Article e57009. https://doi.org/10.3791/57009
    • ten Cate-Hoek, N. J. (2018). Prevention and treatment of the post-thrombotic syndrome. Research and practice in thrombosis and haemostasis, 2(2), 209-219. https://doi.org/10.1002/rth2.12085
    • Nagler, M., ten Cate, H., Prins, M. H., & ten Cate-Hoek, A. J. (2018). Risk factors for recurrence in deep vein thrombosis patients following a tailored anticoagulant treatment incorporating residual vein obstruction. Research and practice in thrombosis and haemostasis, 2(2), 299-309. https://doi.org/10.1002/rth2.12079
    • Olie, R. H., van der Meijden, P. E. J., & ten Cate, H. (2018). The coagulation system in atherothrombosis: Implications for new therapeutic strategies. Research and practice in thrombosis and haemostasis, 2(2), 188-198. https://doi.org/10.1002/rth2.12080
    • Borst, O., Munzer, P., Alnaggar, N., Geue, S., Tegtmeyer, R., Rath, D., Droppa, M., Seizer, P., Heitmeier, S., Heemskerk, J. W. M., Jennings, L. K., Storey, R. F., Angiolillo, D. J., Rocca, B., Spronk, H., Ten Cate, H., Gawaz, M., & Geisler, T. (2018). Inhibitory mechanisms of very low-dose rivaroxaban in non-ST-elevation myocardial infarction. Blood advances, 2(6), 715-730. https://doi.org/10.1182/bloodadvances.2017013573
    • de Brouwer, B., Drent, M., van den Ouweland, J. M. W., Wijnen, P. A., van Moorsel, C. H. M., Bekers, O., Grutters, J. C., White, E. S., & Janssen, R. (2018). Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis. Respiratory Research, 19, Article 45. https://doi.org/10.1186/s12931-018-0747-6
    • Miller, M. C., Ludwig, A.-K., Wichapong, K., Kaltner, H., Kopitz, J., Gabius, H.-J., & Mayo, K. H. (2018). Adhesion/growth-regulatory galectins tested in combination: evidence for formation of hybrids as heterodimers. Biochemical Journal, 475(5), 1003-1018. https://doi.org/10.1042/BCJ20170658
    • Mori, J., Nagy, Z., Di Nunzio, G., Smith, C. W., Geer, M. J., Al Ghaithi, R., van Geffen, J. P., Heising, S., Boothman, L., Tullemans, B. M. E., Correia, J. N., Tee, L., Kuijpers, M. J. E., Harrison, P., Heemskerk, J. W. M., Jarvis, G. E., Tarakhovsky, A., Weiss, A., Mazharian, A., & Senis, Y. A. (2018). Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148. Blood, 131(10), 1122-1144. https://doi.org/10.1182/blood-2017-02-768077
    • de Lange, N., Schol, P., Lance, M., Woiski, M., Langenveld, J., Rijnders, R., Smits, L., Wassen, M., Henskens, Y., & Scheepers, H. (2018). Restrictive Versus Massive Fluid Resuscitation Strategy (REFILL study), influence on blood loss and hemostatic parameters in obstetric hemorrhage: study protocol for a randomized controlled trial. Trials, 19, Article 166. https://doi.org/10.1186/s13063-018-2512-z
    • Silva, C. T., Zorkoltseva, I. V., Niemeijer, M. N., van den Berg, M. E., Amin, N., Demirkan, A., van Leeuwen, E., Iglesias, A. I., Pineros-Hernandez, L. B., Restrepo, C. M., Kors, J. A., Kirichenko, A. V., Willemsen, R., Oostra, B. A., Stricker, B. H., Uitterlinden, A. G., Axenovich, T. I., van Duijn, C. M., & Isaacs, A. (2018). A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy. BMC Medical Genomics, 11, Article 22. https://doi.org/10.1186/s12920-018-0339-9
    • Ruhle, F., & Stoll, M. (2018). Advances in predicting venous thromboembolism risk in children. British Journal of Haematology, 180(5), 654-665. https://doi.org/10.1111/bjh.15060
    • Seyerle, A. A., Sitlani, C. M., Noordam, R., Gogarten, S. M., Li, J., Li, X., Evans, D. S., Sun, F., Laaksonen, M. A., Isaacs, A., Kristiansson, K., Highland, H. M., Stewart, J. D., Harris, T. B., Trompet, S., Bis, J. C., Peloso, G. M., Brody, J. A., Broer, L., ... Avery, C. L. (2018). Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. Pharmacogenomics Journal, 18(2), 215-226. https://doi.org/10.1038/tpj.2017.10