Junho, C. V. C., Dai, Y., Schieren, L., Hourtz, S., Rykova, T., Vondenhoff, S., Wessiepe, M., Zou, J., Jankowski, J., Goettsch, C., & Noels, H. (2026). Advanced glycation end product (AGE)-modified albumin does not enhance neutrophil extracellular trap formation and minimally impacts endothelial inflammation in large vessels. Life Sciences, 398, Article 124467. https://doi.org/10.1016/j.lfs.2026.124467

Navarro, S., Beck, S., Bonfiglio, S. I., Cuenca-Zamora, E. J., Weiss, L. J., Kuijpers, M., Heemskerk, J., Stegner, D., & Nieswandt, B. (2026). Partial downregulation of platelet glycoprotein VI by low affinity antibodies confers sustained and safe antithrombotic protection. Signal Transduction and Targeted Therapy, 11(1), Article 264. https://doi.org/10.1038/s41392-026-02864-5

Evans, B. R., Schulz, J., Triantafyllidou, V., Yerly, A., Thakur, M., Angliker, N., Siegrist, M., Jansen, Y., Yan, Y., Maas, S. L., Gold, C., Farina, F. M., Bayer, B., Bartelt, A., Weber, C., Wettich, J., Maegdefessel, L., Sachs, N., Schindewolf, M., ... Doering, Y. (2026). ChemR23 prevents phenotypic switching of vascular smooth muscle cells into macrophage-like foam cells in atherosclerosis. Cardiovascular Research, 122(2), 195-213. https://doi.org/10.1093/cvr/cvaf258

Thakur, M., Quillard, T., Angliker, N., Siegrist, M., Jansen, Y., Yan, Y., Wollenhaupt, J., Goettsch, C., Maegdefessel, L., Sachs, N., Schindewolf, M., Kotelis, D., Noels, H., & Döring, Y. (2026). DDR1 Regulates Femoral Arterial Calcification in Lower-Extremity Artery Disease Through NF-Kappa B Activation. Acta Physiologica, 242(1), Article e70146. https://doi.org/10.1111/apha.70146

Mikolajetz, D., Kalim, S., Noels, H., Wu, Z., Jankowski, V., Jankowski, J., & de la Puente-secades, S. (2026). Impact of amino acid supplementation on cardiovascular and chronic kidney diseases: a systematic review. Cardiovascular Research, 122(2), 178-194. https://doi.org/10.1093/cvr/cvag007

Bhargava, S., Rao, Z., Vanholder, R., Tacke, F., Noels, H., Jankowski, V., Hermann, J., & Jankowski, J. (2026). The impact of gut-liver-derived mediators on the organ crosstalk with brain, heart, and kidney: A systematic review. Molecular Metabolism, 103, Article 102295. https://doi.org/10.1016/j.molmet.2025.102295

Schnidrig, K., Thakur, M., Tuleja, A., Bernhard, S. M., Noels, H., Kotelis, D., Schindewolf, M., & Doring, Y. (2026). Implications of inflammation and sex in lower extremity arterial disease. European Journal of Clinical Investigation, 56(1), Article e70144. https://doi.org/10.1111/eci.70144

Feng, M., Thevenot, A., Kuntz, S., Liu, C., Schellenberg, C., Charle, L., Brouard, N., Schaeffer, C., Ortiz, S. J., Cosemans, J. M. E. M., Chakfe, N., & Mangin, P. H. (2025). Aortic atherosclerotic plaques are more thrombogenic than carotid and femoral plaques: the role of fibrillar collagen. Atherosclerosis, 411, Article 120552. https://doi.org/10.1016/j.atherosclerosis.2025.120552

Yerly, A., van der Vorst, E. P. C., Schindewolf, M., Kotelis, D., Noels, H., & Doring, Y. (2025). Chemokine-receptor-guided B-cell immunity in cardiovascular disease. Basic Research in Cardiology, 120(6), 1075-1090. https://doi.org/10.1007/s00395-025-01140-x

D'Italia, G., Coenen, D. M., Lemmens, T. P., Brandts, L., Wielders, S. J. H., Nagy, M., Mourmans, S. G. J., Achten, A., Al-Abadi, A., Weerts, J., Aizpurua, A. B., van Empel, V., Schroen, B., & Cosemans, J. M. E. M. (2025). Immuno-haemostatic dysregulation in heart failure with preserved ejection fraction. Esc heart failure, 12(5), 3444-3460. https://doi.org/10.1002/ehf2.15361

Octave, M., Pirotton, L., de Cartier d'Yves, E., Marino, A., Ambroise, J., Giera, M., Guigas, B., Ginion, A., Robaux, V., Kuijpers, M. J. E., Baaten, C. C. F. M. J., Heemskerk, J. W. M., Nagy, Z., Senis, Y. A., Brusa, D., Bouzin, C., Bertrand, L., Beauloye, C., & Horman, S. (2025). Deleting ACC1 in platelets alters phospholipidome and reduces platelet activation and thrombosis in mice. Blood advances, 9(18), 4553-4567. https://doi.org/10.1182/bloodadvances.2025015796

Baaten, C. C. F. M. J., Wollenhaupt, J., Henning, T. M., Vondenhoff, S., Schröer, J. R., Stamellou, E., Saritas, T., Kurt, B., Boger, L., Antwerpen, A., Hermann, J., Nagy, M., Sternkopf, M., Buhl, E. M., Raffetseder, U., van der Meijden, P. E. J., Kuijpers, M. J. E., Spronk, H. M. H., Schunk, S. J., ... Noels, H. (2025). Impaired Secondary Platelet Response in Chronic Kidney Disease as a Consequence of Prior Platelet Activation. JACC: Basic to Translational Science, 10(9), Article 101355. https://doi.org/10.1016/j.jacbts.2025.101355

Lauxen, J. S., Vondenhoff, S., Junho, C. V. C., Martin, P., Fleig, S., Schuett, K., Schulze-Spaete, U., Soehnlein, O., Prates-Roma, L., Doering, Y., Baaten, C. C. F. M. J., & Noels, H. (2025). Neutrophil Function in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Acta Physiologica, 241(6), Article e70057. https://doi.org/10.1111/apha.70057

Noels, H., van der Vorst, E. P. C., Rubin, S., Emmett, A., Marx, N., Tomaszewski, M., & Jankowski, J. (2025). Renal-Cardiac Crosstalk in the Pathogenesis and Progression of Heart Failure. Circulation Research, 136(11), 1306-1334. https://doi.org/10.1161/CIRCRESAHA.124.325488

D'Italia, G., Schroen, B., & Cosemans, J. M. E. M. (2025). Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities. Esc heart failure, 12(2), 1013-1028. Article 15090. https://doi.org/10.1002/ehf2.15090

Liehr, T., Kankel, S., Hardt, K. S., Buhl, E. M., Noels, H., Keller, D. T., Schröder-Lange, S. K., & Weiskirchen, R. (2025). Genetic and Molecular Characterization of H9c2 Rat Myoblast Cell Line. Cells, 14(7), Article 502. https://doi.org/10.3390/cells14070502

de la Puente-secades, S., Mikolajetz, D., Gayrard, N., Hermann, J., Jankowski, V., Bhargava, S., Meyer, A., Argiles, A., Saritas, T., van der Vorst, E. P. C., Wu, Z., Noels, H., Tepel, M., Alghamdi, K., Ward, D., Zidek, W., Wolf, M., Floege, J., Schurgers, L., ... Jankowski, J. (2025). Vasoconstriction-inhibiting factor: an endogenous inhibitor of vascular calcification as a calcimimetic of calcium-sensing receptor. Cardiovascular Research, 121(3), 507-521. https://doi.org/10.1093/cvr/cvaf016

Schulze-Spaete, U., Wurschi, L., van der Vorst, E. P. C., Hoelzle, F., Craveiro, R. B., Wolf, M., & Noels, H. (2024). Crosstalk between periodontitis and cardiovascular risk. Frontiers in Immunology, 15, Article 1469077. https://doi.org/10.3389/fimmu.2024.1469077

Lemmens, T. P., Luo, Q., Wielders, S. J. H., Scheijen, J. L. J. M., Al-Nasiry, S., Koenen, R. R., Wenzel, P., & Cosemans, J. M. E. M. (2024). Platelet collagen receptors and their role in modulating platelet adhesion patterns and activation on alternatively processed collagen substrates. Thrombosis Research, 244, Article 109201. https://doi.org/10.1016/j.thromres.2024.109201

Jooss, N. J., Diender, M. G., Fernandez, D. I., Huang, J., Heubel-Moenen, F. C. J., van der Veer, A., Kuijpers, M. J. E., Poulter, N. S., Henskens, Y. M. C., te Loo, M., & Heemskerk, J. W. M. (2024). Restraining of glycoprotein VI- and integrin α2β1-dependent thrombus formation by platelet PECAM1. Cellular and Molecular Life Sciences, 81(1), Article 44. https://doi.org/10.1007/s00018-023-05058-2

Zou, J., Zhang, P., Solari, F. A., Schönichen, C., Provenzale, I., Mattheij, N. J. A., Kuijpers, M. J. E., Rauch, J. S., Swieringa, F., Sickmann, A., Zieger, B., Jurk, K., & Heemskerk, J. W. M. (2024). Suppressed ORAI1-STIM1-dependent Ca2+ entry by protein kinase C isoforms regulating platelet procoagulant activity. Journal of Biological Chemistry, 300(12), Article 107899. https://doi.org/10.1016/j.jbc.2024.107899

Fernández, D. I., Troitiño, S., Sobota, V., Tullemans, B. M. E., Zou, J., van den Hurk, H., García, Á., Honarnejad, S., Kuijpers, M. J. E., & Heemskerk, J. W. M. (2024). Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics. Scientific Reports, 14(1), Article 6229. https://doi.org/10.1038/s41598-024-56799-4

Lellig, M., Rodríguez, M., López-Baltanás, R., Hermann, J., Wollenhaupt, J., Noels, H., Zidek, W., Tepel, M., Mahfoud, F., Jankowski, J., Muñoz-Castañeda, J. R., & Jankowski, V. (2024). Pyridoxal-5'-phosphate: A cost-effective treatment candidate for hypertensive patients?Journal of Internal Medicine, 296(5), 435-448. https://doi.org/10.1111/joim.20015

Dai, Y., Junho, C. V. C., Schieren, L., Wollenhaupt, J., Sluimer, J. C., van der Vorst, E. P. C., & Noels, H. (2024). Cellular metabolism changes in atherosclerosis and the impact of comorbidities. Frontiers in Cell and Developmental Biology, 12, Article 1446964. https://doi.org/10.3389/fcell.2024.1446964

Noels, H., Jankowski, V., Schunk, S. J., Vanholder, R., Kalim, S., & Jankowski, J. (2024). Post-translational modifications in kidney diseases and associated cardiovascular risk. Nature Reviews Nephrology, 20(8), 495-512. https://doi.org/10.1038/s41581-024-00837-x

Stamellou, E., Noels, H., & Floege, J. (2024). Factor XI inhibition in hemodialysis patients: the safer anticoagulation?Kidney International, 106(1), 21-23. https://doi.org/10.1016/j.kint.2024.03.029

Zhang, P., von Ungern-Sternberg, S., Hastenplug, L., Solari, F., Sickmann, A., Kuijpers, M., Heemskerk, J. W., Walter, U., & Jurk, K. (2024). Multi-phased kinetics and interaction of protein kinase signaling in glycoprotein VI-induced platelet αIIbβ3 integrin activation and degranulation. Thrombosis and Haemostasis, 125(5), 470-483. https://doi.org/10.1055/a-2311-0117

Lemmens, T. P., Bröker, V., Rijpkema, M., Hughes, C. C. W., Schurgers, L. J., & Cosemans, J. M. E. M. (2024). Fundamental considerations for designing endothelialized in vitro models of thrombosis. Thrombosis Research, 236, 179-190. https://doi.org/10.1016/j.thromres.2024.03.004

Melo, S. F., Nondonfaz, A., Aqil, A., Pierrard, A., Hulin, A., Delierneux, C., Ditkowski, B., Gustin, M., Legrand, M., Tullemans, B. M. E., Brouns, S. L. N., Nchimi, A., Carrus, R., Dejosé, A., Heemskerk, J. W. M., Kuijpers, M. J. E., Ritter, J., Steinseifer, U., Clauser, J. C., ... Oury, C. (2024). Design, manufacturing and testing of a green non-isocyanate polyurethane prosthetic heart valve. Biomaterials Science, 12(8), 2149-2164. https://doi.org/10.1039/d3bm01911j

Harlacher, E., Schulte, C., Vondenhoff, S., Schmitt-Kopplin, P., Diederich, P., Hemmers, C., Moellmann, J., Wollenhaupt, J., Veltrop, R., Biessen, E., Lehrke, M., Peters, B., Schlieper, G., Kuppe, C., Floege, J., Jankowski, V., Marx, N., Jankowski, J., & Noels, H. (2024). Increased levels of a mycophenolic acid metabolite in patients with kidney failure negatively affect cardiomyocyte health. Frontiers in Cardiovascular Medicine, 11, Article 1346475. https://doi.org/10.3389/fcvm.2024.1346475

Vondenhoff, S., Schunk, S. J., & Noels, H. (2024). Erhöhtes kardiovaskuläres Risiko bei Patienten mit chronischer Niereninsuffizienz. Herz, 49(2), 95-104. https://doi.org/10.1007/s00059-024-05235-4

Provenzale, I., Solari, F. A., Schoenichen, C., Brouns, S. L. N., Fernandez, D. I., Kuijpers, M. J. E., van Der Meijden, P. E. J., Gibbins, J. M., Sickmann, A., Jones, C., & Heemskerk, J. W. M. (2024). Endothelium-mediated regulation of platelet activation: Involvement of multiple protein kinases. Faseb Journal, 38(4), Article e23468. https://doi.org/10.1096/fj.202300360RR

Junho, C. V. C., Frisch, J., Soppert, J., Wollenhaupt, J., & Noels, H. (2023). Cardiomyopathy in chronic kidney disease: clinical features, biomarkers and the contribution of murin models in understanding pathophysiology. Clinical Kidney Journal, 16(11), 1786-1803. https://doi.org/10.1093/ckj/sfad085

Oury, C., Meyers, S., Jacques, N., Leeten, K., Jiang, Z., Musumeci, L., Lox, M., Debuisson, M., Goffin, E., Pirotte, B., Delvenne, P., Nchimi, A., Hubert, C., Heptia, M., Hubert, P., Kuijpers, M. J. E., Vanassche, T., Martinod, K., Verhamme, P., & Lancellotti, P. (2023). Protective Effect of Ticagrelor Against Infective Endocarditis Induced by Virulent Staphylococcus aureus in Mice. JACC: Basic to Translational Science, 8(11), 1439-1453. https://doi.org/10.1016/j.jacbts.2023.02.003

Baaten, C. C. F. M. J., Vondenhoff, S., Jankowski, J., & Noels, H. (2023). Thrombozytenstörungen bei Urämie: Mediator von Herz- und Gefäßschäden. Die Nephrologie, 18(6), 346–354. https://doi.org/10.1007/s11560-023-00682-2

Yakusheva, A., Slater, A., Payrastre, B., Garcia, C., D'Italia, G., Allan, H., Cosemans, J. M. E. M., Harper, M., Gawaz, M., Armstrong, P., Troitiño, S., Trivigno, S. M. G., Naik, U. P., & Senis, Y. A. (2023). Illustrated Abstracts of the 5^th EUPLAN International Conference. Research and practice in thrombosis and haemostasis, 7(7), Article 102140. https://doi.org/10.1016/j.rpth.2023.102140

Soppert, J., Brandt, E. F., Heussen, N. M., Barzakova, E., Blank, L. M., Kuepfer, L., Hornef, M. W., Trebicka, J., Jankowski, J., Berres, M.-L., & Noels, H. (2023). Blood endotoxin levels as biomarker of non-alcoholic fatty liver disease: a systematic review and meta-analysis. Clinical gastroenterology and hepatology, 21(11), 2746-2758. https://doi.org/10.1016/j.cgh.2022.11.030

Schönichen, C., Montague, S. J., Brouns, S. L. N., Burston, J. J., Cosemans, J. M. E. M., Jurk, K., Kehrel, B. E., Koenen, R. R., Ní Áinle, F., O'Donnell, V. B., Soehnlein, O., Watson, S. P., Kuijpers, M. J. E., Heemskerk, J. W. M., & Nagy, M. (2023). Antagonistic Roles of Human Platelet Integrin αiIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi under Flow. Arteriosclerosis Thrombosis and Vascular Biology, 43(9), 1700-1712. https://doi.org/10.1161/ATVBAHA.122.318767

Fernandez, D. I., Diender, M., Hermida-Nogueira, L., Huang, J., Veiras, S., Henskens, Y. M. C., te Loo, M. W. M., Heemskerk, J. W. M., Kuijpers, M. J. E., & Garcia, A. (2023). Role of SHP2 (PTPN11) in glycoprotein VI-dependent thrombus formation: Improved platelet responsiveness by the allosteric drug SHP099 in Noonan syndrome patients. Thrombosis Research, 228(1), 105-116. https://doi.org/10.1016/j.thromres.2023.06.001

Josefsson, E. C., Ramstrom, S., Thaler, J., Lordkipanidze, M., Cosemans, J., & COAGAPO Study Group (2023). Consensus report on markers to distinguish procoagulant platelets from apoptotic platelets: communication from the Scientific and Standardization Committee of the ISTH. Journal of Thrombosis and Haemostasis, 21(8), 2291-2299. https://doi.org/10.1016/j.jtha.2023.05.001

van Kuijk, K., McCracken, I. R., Tillie, R. J. H. A., Asselberghs, S. E. J., Kheder, D. A., Muitjens, S., Jin, H., Taylor, R. S., Schreur, R. W., Kuppe, C., Dobie, R., Ramachandran, P., Gijbels, M. J., Temmerman, L., Kirkwoord, P. M., Luyten, J., Li, Y. M., Noels, H., Goossens, P., ... Sluimer, J. C. (2023). Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol. Cardiovascular Research, 119(7), 1509-1523. https://doi.org/10.1093/cvr/cvad016

Antunes-Ferreira, M., D'Ambrosi, S., Arkani, M., Post, E., In 't Veld, S. G. J. G., Ramaker, J., Zwaan, K., Kucukguzel, E. D., Wedekind, L. E., Griffioen, A. W., Egbrink, M. O., Kuijpers, M. J. E., van den Broek, D., Noske, D. P., Hartemink, K. J., Sabrkhany, S., Bahce, I., Sol, N., Bogaard, H.-J., ... Wurdinger, T. (2023). Tumor-educated platelet blood tests for Non-Small Cell Lung Cancer detection and management. Scientific Reports, 13(1), Article 9359. https://doi.org/10.1038/s41598-023-35818-w

Sabrkhany, S., Kuijpers, M. J. E., Van Kuijk, S. M. J., Griffioen, A. W., & Oude Egbrink, M. G. A. (2023). Age- and gender-matched controls needed for platelet-based biomarker studies. Haematologica-the Hematology Journal, 108(6), 1667-1670. https://doi.org/10.3324/haematol.2022.281726

Soppert, J., Heussen, N. M., & Noels, H. (2023). The authors reply. Kidney International, 103(6), 1199-1201. https://doi.org/10.1016/j.kint.2023.02.023

Zhang, P., Solari, F. A., Heemskerk, J. W. M., Kuijpers, M. J. E., Sickmann, A., Walter, U., & Jurk, K. (2023). Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets. International Journal of Molecular Sciences, 24(9), Article 7776. https://doi.org/10.3390/ijms24097776

Baaten, C. C. F. M. J., Vondenhoff, S., & Noels, H. (2023). Endothelial Cell Dysfunction and Increased Cardiovascular Risk in Patients With Chronic Kidney Disease. Circulation Research, 132(8), 970-992. https://doi.org/10.1161/CIRCRESAHA.123.321752

Noels, H., & Jankowski, J. (2023). Increased Risk of Cardiovascular Complications in Chronic Kidney Disease: Introduction to a Compendium. Circulation Research, 132(8), 899-901. https://doi.org/10.1161/CIRCRESAHA.123.322806

Thakur, M., Junho, C. V. C., Bernhard, S. M., Schindewolf, M., Noels, H., & Doring, Y. (2023). NETs-Induced Thrombosis Impacts on Cardiovascular and Chronic Kidney Disease. Circulation Research, 132(8), 933-949. https://doi.org/10.1161/CIRCRESAHA.123.321750