• 2021
    • Bukkems, L. H., Heijdra, J. M., de Jager, N. C. B., Hazendonk, H. C. A. M., Fijnvandraat, K., Meijer, K., Eikenboom, J. C. J., Laros-Van Gorkom, B. A. P., Leebeek, F. W. G., Cnossen, M. H., Mathôt, R. A. A., Coppens, K. F. M., Kruip, M. J. H. A., Polinder, S., Lock, J., Hazendonk, H. C. A. M., van Moort, I., Heijdra, J. M., Goedhart, M. C. H. J., ... OPTI-CLOT Study Group (2021). Population pharmacokinetics of the von Willebrand factor-factor VIII interaction in patients with von Willebrand disease. Blood advances, 5(5), 1513-1522. https://doi.org/10.1182/BLOODADVANCES.2020003891
    • van Rosmalen, F., Maesen, B., van Hunnik, A., Hermans, B. J. M., Bonizzi, P., Bidar, E., Nijs, J., Maessen, J. G., Verheule, S., Delhaas, T., Schotten, U., & Zeemering, S. (2021). Incidence, prevalence, and trajectories of repetitive conduction patterns in human atrial fibrillation. EP Europace, 23(Supplement_1), i123-i132. https://doi.org/10.1093/europace/euaa403
    • Hulshof, A.-M., Hemker, H. C., Spronk, H. M. H., Henskens, Y. M. C., & Ten Cate, H. (2021). Thrombin-Fibrin(ogen) Interactions, Host Defense and Risk of Thrombosis. International journal of molecular sciences, 22(5), Article 2590. https://doi.org/10.3390/ijms22052590
    • Zhou, T. L., Kroon, A. A., Henry, R. M. A., Koster, A., Dagnelie, P. C., Bosma, H., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schalkwijk, C. G., Wesselius, A., Reesink, K. D., Köhler, S., Schram, M. T., Stehouwer, C. D. A., & van Sloten, T. T. (2021). Exercise SBP response and incident depressive symptoms: The Maastricht Study. Journal of Hypertension, 39(3), 494-502. https://doi.org/10.1097/HJH.0000000000002657
    • Agten, S. M., Watson, E. E., Ripoll-Rozada, J., Dowman, L. J., Wu, M. C. L., Alwis, I., Jackson, S. P., Pereira, P. J. B., & Payne, R. J. (2021). Potent Trivalent Inhibitors of Thrombin through Hybridization of Salivary Sulfopeptides from Hematophagous Arthropods. Angewandte Chemie-International Edition, 60(10), 5348-5356. https://doi.org/10.1002/anie.202015127
    • Apostel, H. J. C. L., Winckers, K., Bidar, E., & Schreiber, J. U. (2021). Successful Antithrombin Administration in Andexanet Alfa-Associated Heparin Resistance. Journal of Cardiothoracic and Vascular Anesthesia, 35(3), 904-907. https://doi.org/10.1053/j.jvca.2020.10.042
    • Henderson, J. M., Weber, C., & Santovito, D. (2021). Beyond Self-Recycling: Cell-Specific Role of Autophagy in Atherosclerosis. Cells, 10(3), Article 625. https://doi.org/10.3390/cells10030625
    • Koenen, R. R. (2021). Conformation-Crooking CXCL4 to Unravel Autoimmune Heparin-Induced Thrombocytopenia. Thrombosis and Haemostasis, 121(03), 258-260. https://doi.org/10.1055/s-0040-1721774
    • Fabritz, L., Crijns, H. J. G. M., Guasch, E., Goette, A., Häusler, K. G., Kotecha, D., Lewalter, T., Meyer, C., Potpara, T. S., Rienstra, M., Schnabel, R. B., Willems, S., Breithardt, G., Camm, A. J., Chan, A., Chua, W., de Melis, M., Dimopoulou, C., Dobrev, D., ... Kirchhof, P. (2021). Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference. EP Europace, 23(3), 329-344. https://doi.org/10.1093/europace/euaa279
    • Kaptein, F. H. J., Stals, M. A. M., Grootenboers, M., Braken, S. J. E., Burggraaf, J. L. I., van Bussel, B. C. T., Cannegieter, S. C., Ten Cate, H., Endeman, H., Gommers, D. A. M. P. J., van Guldener, C., de Jonge, E., Juffermans, N. P., Kant, K. M., Kevenaar, M. E., Koster, S., Kroft, L. J. M., Kruip, M. J. H. A., Leentjens, J., ... Dutch COVID & Thrombosis Coalition (2021). Incidence of thrombotic complications and overall survival in hospitalized patients with COVID-19 in the second and first wave. Thrombosis Research, 199, 143-148. https://doi.org/10.1016/j.thromres.2020.12.019
    • Natarelli, L., Parca, L., Mazza, T., Weber, C., Virgili, F., & Fratantonio, D. (2021). MicroRNAs and Long Non-Coding RNAs as Potential Candidates to Target Specific Motifs of SARS-CoV-2. Non-coding RNA, 7(1), Article 14. https://doi.org/10.3390/ncrna7010014
    • Hassan, S., Monahan, R. C., Mauser-Bunschoten, E. P., van Vulpen, L. F. D., Eikenboom, J., Beckers, E. A. M., Hooimeijer, L., Ypma, P. F., Nieuwenhuizen, L., Coppens, M., Schols, S. E. M., Leebeek, F. W. G., Smit, C., Driessens, M. H., le Cessie, S., van Balen, E. C., Rosendaal, F. R., van Der Bom, J. G., & Gouw, S. C. (2021). Mortality, life expectancy, and causes of death of persons with hemophilia in the Netherlands 2001-2018. Journal of Thrombosis and Haemostasis, 19(3), 645-653. https://doi.org/10.1111/jth.15182
    • Notten, P., ten Cate, H., & ten Cate-Hoek, A. J. (2021). Postinterventional antithrombotic management after venous stenting of the iliofemoral tract in acute and chronic thrombosis: A systematic review. Journal of Thrombosis and Haemostasis, 19(3), 753-796. https://doi.org/10.1111/jth.15197
    • Hermans, B. J. M., Zink, M. D., van Rosmalen, F., Crijns, H. J. G. M., Vernooy, K., Postema, P., Pison, L., Schotten, U., & Delhaas, T. (2021). Pulmonary vein isolation in a real-world population does not influence QTc interval. EP Europace, 23, I48-I54. https://doi.org/10.1093/europace/euaa390
    • Santovito, D., Toto, L., De Nardis, V., Marcantonio, P., D'Aloisio, R., Mastropasqua, A., De Cesare, D., Bucci, M., Paganelli, C., Natarelli, L., Weber, C., Consoli, A., Mastropasqua, R., & Cipollone, F. (2021). Plasma microRNA signature associated with retinopathy in patients with type 2 diabetes. Scientific Reports, 11(1), Article 4136. https://doi.org/10.1038/s41598-021-83047-w
    • Miller, M. C., Zheng, Y., Suylen, D., Ippel, H., Canada, F. J., Berbis, M. A., Jimenez-Barbero, J., Tai, G., Gabius, H.-J., & Mayo, K. H. (2021). Targeting the CRD F-face of Human Galectin-3 and Allosterically Modulating Glycan Binding by Angiostatic PTX008 and a Structurally Optimized Derivative. Chemmedchem, 16(4), 713-723. https://doi.org/10.1002/cmdc.202000742
    • Lagou, V., Mägi, R., Hottenga, J. J., Grallert, H., Perry, J. R. B., Bouatia-Naji, N., Marullo, L., Rybin, D., Jansen, R., Min, J. L., Dimas, A. S., Ulrich, A., Zudina, L., Gådin, J. R., Jiang, L., Faggian, A., Bonnefond, A., Fadista, J., Stathopoulou, M. G., ... Prokopenko, I. (2021). Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nature Communications, 12(1), Article 995. https://doi.org/10.1038/s41467-021-21276-3
    • Mezger, S. T. P., Mingels, A. M. A., Bekers, O., Heeren, R. M. A., & Cillero-Pastor, B. (2021). Mass Spectrometry Spatial-Omics on a Single Conductive Slide. Analytical Chemistry, 93(4), 2527-2533. https://doi.org/10.1021/acs.analchem.0c04572
    • Raadsen, M., Du Toit, J., Langerak, T., van Bussel, B., van Gorp, E., & Goeijenbier, M. (2021). Thrombocytopenia in Virus Infections. Journal of Clinical Medicine, 10(4), Article 877. https://doi.org/10.3390/jcm10040877
    • van Gassel, R. J. J., Bels, J. L. M., Raafs, A., van Bussel, B. C. T., van de Poll, M. C. G., Simons, S. O., van der Meer, L. W. L., Gietema, H. A., Posthuma, R., & van Santen, S. (2021). High Prevalence of Pulmonary Sequelae at 3 Months after Hospital Discharge in Mechanically Ventilated Survivors of COVID-19. American Journal of Respiratory and Critical Care Medicine, 203(3), 371-374. https://doi.org/10.1164/rccm.202010-3823LE
    • Gencer, S., Evans, B. R., van der Vorst, E. P. C., Doring, Y., & Weber, C. (2021). Inflammatory Chemokines in Atherosclerosis. Cells, 10(2), Article 226. https://doi.org/10.3390/cells10020226
    • Coenen, D. M., Heinzmann, A. C. A., Karel, M. F. A., Cosemans, J. M. E. M., & Koenen, R. R. (2021). The multifaceted contribution of platelets in the emergence and aftermath of acute cardiovascular events. Atherosclerosis, 319, 132-141. https://doi.org/10.1016/j.atherosclerosis.2020.12.017
    • Kruip, M. J. H. A., Cannegieter, S. C., ten Cate, H., van Gorp, E. C. M., Juffermans, N. P., Klok, F. A., Maas, C., Vonk-Noordegraaf, A., & Dutch & COVID Thrombosis Coalition study group (2021). Caging the dragon: Research approach to COVID-19-related thrombosis. Research and practice in thrombosis and haemostasis, 5(2), 278-291. https://doi.org/10.1002/rth2.12470
    • Hanssen, N. M. J., Scheijen, J. L. J. M., Houben, A. J. H. M., van de Waarenburg, M., Berendschot, T. T. J. M., Webers, C. A. B., Reesink, K. D., van Greevenbroek, M. M. J., van der Kallen, C., Schaper, N. C., Schram, M. T., Henry, R. M. A., Stehouwer, C. D. A., & Schalkwijk, C. G. (2021). Fasting and post-oral-glucose-load levels of methylglyoxal are associated with microvascular, but not macrovascular, disease in individuals with and without (pre)diabetes: The Maastricht Study. Diabetes & Metabolism, 47(1), Article 101148. https://doi.org/10.1016/j.diabet.2020.02.002
    • Perrella, G., Huang, J., Provenzale, I., Swieringa, F., Heubel-Moenen, F. C. J., Farndale, R. W., Roest, M., van der Meijden, P. E. J., Thomas, M., Ariens, R. A. S., Jandrot-Perrus, M., Watson, S. P., & Heemskerk, J. W. M. (2021). Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation. Arteriosclerosis Thrombosis and Vascular Biology, 41(2), E97-E111. https://doi.org/10.1161/ATVBAHA.120.314641
    • Squiccimarro, E., Jiritano, F., Serraino, G. F., ten Cate, H., Paparella, D., & Lorusso, R. (2021). Quantitative and Qualitative Platelet Derangements in Cardiac Surgery and Extracorporeal Life Support. Journal of Clinical Medicine, 10(4), Article 615. https://doi.org/10.3390/jcm10040615
    • van Paridon, P. C. S., Panova-Noeva, M., van Oerle, R., Schulz, A., Prochaska, J. H., Arnold, N., Schmidtmann, I., Beutel, M., Pfeiffer, N., Muenzel, T., Lackner, K. J., Hackeng, T. M., ten Cate, H., Wild, P. S., & Spronk, H. M. H. (2021). Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample. Thrombosis and Haemostasis, 121(02), 174-181. https://doi.org/10.1055/s-0040-1715897
    • Limperger, V., Kenet, G., Kiesau, B., Koether, M., Schmeiser, M., Langer, F., Juhl, D., Shneyder, M., Franke, A., Klostermeier, U. K., Mesters, R., Ruehle, F., Stoll, M., Steppat, D., Kowalski, D., Rocke, A., Kuta, P., Bajorat, T., Torge, A., ... Nowak-Goettl, U. (2021). Role of prothrombin 19911 A > G polymorphism, blood group and male gender in patients with venous thromboembolism: Results of a German cohort study. Journal of Thrombosis and Thrombolysis, 51(2), 494-501. https://doi.org/10.1007/s11239-020-02169-6
    • Eggebrecht, L., Ludolph, P., Gobel, S., Panova-Noeva, M., Arnold, N., Nagler, M., Bickel, C., Lauterbach, M., Hardt, R., Ten Cate, H., Lackner, K. J., Espinola-Klein, C., Munzel, T., Prochaska, J. H., & Wild, P. S. (2021). Cost saving analysis of specialized, eHealth-based management of patients receiving oral anticoagulation therapy: Results from the thrombEVAL study. Scientific Reports, 11(1), Article 2577. https://doi.org/10.1038/s41598-021-82076-9
    • Calisto, B., Ripoll-Rozada, J., Dowman, L. J., Franck, C., Agten, S., Parker, B. L., Carvalho Veloso, R., Vale, N., Gomes, P., de Sanctis, D., Payne, R. J., & Pereira, P. J. B. (2021). Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates. Cell Chemical Biology, 28(1), 26-33.e8. https://doi.org/10.1016/j.chembiol.2020.10.002
    • van Doorn, W. P. T. M., Stassen, P. M., Borggreve, H. F., Schalkwijk, M. J., Stoffers, J., Bekers, O., & Meex, S. J. R. (2021). A comparison of machine learning models versus clinical evaluation for mortality prediction in patients with sepsis. PLOS ONE, 16(1), Article 0245157. https://doi.org/10.1371/journal.pone.0245157
    • Schumski, A., Ortega-Gómez, A., Wichapong, K., Winter, C., Lemnitzer, P., Viola, J. R., Pinilla-Vera, M., Folco, E., Solis-Mezarino, V., Völker-Albert, M., Maas, S. L., Pan, C., Perez Olivares, L., Winter, J., Hackeng, T., Karlsson, M. C. I., Zeller, T., Imhof, A., Baron, R. M., ... Soehnlein, O. (2021). Endotoxinemia Accelerates Atherosclerosis Through Electrostatic Charge-Mediated Monocyte Adhesion. Circulation, 143(3), 254-266. https://doi.org/10.1161/circulationaha.120.046677
    • Driessen, R. G. H., Heijnen, N. F. L., Hulsewe, R. P. M. G., Holtkamp, J. W. M., Winkens, B., van de Poll, M. C. G., van der Horst, I. C. C., Bergmans, D. C. J. J., & Schnabel, R. M. (2021). Early ICU-mortality in sepsis - causes, influencing factors and variability in clinical judgement: a retrospective cohort study. Infectious Diseases, 53(1), 61-68. https://doi.org/10.1080/23744235.2020.1821912
    • Wu, J. Y., Heemskerk, J. W. M., & Baaten, C. C. F. M. J. (2021). Platelet Membrane Receptor Proteolysis: Implications for Platelet Function. Frontiers in Cardiovascular Medicine, 7, Article 608391. https://doi.org/10.3389/fcvm.2020.608391
    • Dickhout, A., Tullemans, B. M. E., Heemskerk, J. W. M., Thijssen, V. L. J. L., Kuijpers, M. J. E., & Koenen, R. R. (2021). Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro. PLOS ONE, 16(1), Article e0244736. https://doi.org/10.1371/journal.pone.0244736
    • Lagou, V., Mägi, R., Hottenga, J. J., Grallert, H., Perry, J. R. B., Bouatia-Naji, N., Marullo, L., Rybin, D., Jansen, R., Min, J. L., Dimas, A. S., Ulrich, A., Zudina, L., Gådin, J. R., Jiang, L., Faggian, A., Bonnefond, A., Fadista, J., Stathopoulou, M. G., ... Morris, A. P. (2021). Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nature Communications, 12(1), Article 24. https://doi.org/10.1038/s41467-020-19366-9
    • van Moerbeke, A., Magdelijns, F., Cleutjens, F., Boonen, A., & van Onna, M. (2021). Development and Evaluation of a Clinic for Elderly Patients with Rheumatoid Arthritis and Multimorbidity: A Pilot Study. ACR open rheumatology, 3(1), 34-40. https://doi.org/10.1002/acr2.11213
    • Kakkos, S. K., Gohel, M., Baekgaard, N., Bauersachs, R., Bellmunt-Montoya, S., Black, S. A., ten Cate-Hoek, A. J., Elalamy, I., Enzmann, F. K., Geroulakos, G., Gottsater, A., Hunt, B. J., Mansilha, A., Nicolaides, A. N., Sandset, P. M., Stansby, G., de Borst, G. J., Goncalves, F. B., Chakfe, N., ... ESVS Guidelines Committee (2021). Editor's Choice – European Society for Vascular Surgery (ESVS) 2021 Clinical Practice Guidelines on the Management of Venous Thrombosis. European Journal of Vascular and Endovascular Surgery, 61(1), 9-82. https://doi.org/10.1016/j.ejvs.2020.09.023
    • Alexander, Y., Osto, E., Schmidt-Trucksass, A., Shechter, M., Trifunovic, D., Duncker, D. J., Aboyans, V., Back, M., Badimon, L., Cosentino, F., De Carlo, M., Dorobantu, M., Harrison, D. G., Guzik, T. J., Hoefer, I., Morris, P. D., Norata, G. D., Suades, R., Taddei, S., ... Evans, P. C. (2021). Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardioloy working Groups on Artherosclerosis and Vascular Biology, Aorta and Perirpheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis. Cardiovascular Research, 117(1), 29-42. https://doi.org/10.1093/cvr/cvaa085
    • Theunissen, M., Rideaux-Seferina, S., Magdelijns, F. J., Janssen, D. J. A., & van den Beuken-van Everdingen, M. H. J. (2021). Local Oral Pilocarpine Drops for Relieving Xerostomia (Dry Mouth) in the Elderly: A Pilot Study. Journal of the American Medical Directors Association, 22(1), 185-186. https://doi.org/10.1016/j.jamda.2020.06.036
    • Lip, G. Y. H., Rigby, A., & Weber, C. (2021). Looking Back on 2020, Looking Forward to 2021. Thrombosis and Haemostasis, 121(01), 1-3. https://doi.org/10.1055/s-0040-1722198
    • Omarova, F., Rosing, J., Bertina, R. M., & Castoldi, E. (2021). Negatively charged phospholipids stimulate factor XI activation by thrombin. Thrombosis Update, 2, Article 100022. https://doi.org/10.1016/j.tru.2020.100022
    • Brinkman, H. J. M., Ahnstrom, J., Castoldi, E., Dahlback, B., & Marlar, R. A. (2021). Pleiotropic anticoagulant functions of protein S, consequences for the clinical laboratory. Communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis, 19(1), 281-286. https://doi.org/10.1111/jth.15108
    • Kimenai, D. M., Appelman, Y., den Ruijter, H. M., Shah, A. S. V., Mills, N. L., & Meex, S. J. R. (2021). Ten Years of High-Sensitivity Cardiac Troponin Testing: Impact on the Diagnosis of Myocardial Infarction. Clinical Chemistry, 67(1), 324-326. https://doi.org/10.1093/clinchem/hvaa272
    • Weber, C., Rigby, A., & Lip, G. Y. H. (2021). Thrombosis and Haemostasis 2020 Editors' Choice Papers. Thrombosis and Haemostasis, 121(01), 109-114. https://doi.org/10.1055/s-0040-1722171
    • van den Kerkhof, D. L., Nagy, M., Wichapong, K., Brouns, S. L. N., Heemskerk, J. W. M., Hackeng, T. M., & Dijkgraaf, I. (2021). Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integrin inhibitor from ticks. Research and practice in thrombosis and haemostasis, 5(1), 231-242. https://doi.org/10.1002/rth2.12466
    • Wichapong, K., Silvestre-Roig, C., Braster, Q., Schumski, A., Soehnlein, O., & Nicolaes, G. A. F. (2021). Structure-based peptide design targeting intrinsically disordered proteins: Novel histone H4 and H2A peptidic inhibitors. Computational and Structural Biotechnology Journal, 19, 934-948. https://doi.org/10.1016/j.csbj.2021.01.026
    • Cornelissen, L. L., Kreuger, A. L., Caram-Deelder, C., Middelburg, R. A., Kerkhoffs, J. L. H., von dem Borne, P. A., Beckers, E. A. M., de Vooght, K. M. K., Kuball, J., Zwaginga, J. J., & van der Bom, J. G. (2021). Thrombocytopenia and the effect of platelet transfusions on the occurrence of intracranial hemorrhage in patients with acute leukemia - a nested case-control study. Annals of Hematology, 100(1), 261-271. https://doi.org/10.1007/s00277-020-04298-7