Publications
- 2003
- Rothkrantz-Kos, S., Bekers, O., Gubbels, A., Drent, M., Schmitz, M. P., & van Dieijen-Visser, M. P. (2003). Evaluation of two new high-sensitivity methods for C-reactive protein. Annals of Clinical Biochemistry, 40(Pt 4), 398-405. https://doi.org/10.1258/000456303766477057
- Briedé, J. J., Wielders, S. J. H., Heemskerk, J. W. M., Baruch, D., Hemker, H. C., & Lindhout, T. (2003). von Willebrand factor stimulates thrombin-induced exposure of procoagulant phospholipids on the surface of fibrin-adherent platelets. Thrombosis and Haemostasis, 1(3), 559-565. https://doi.org/10.1046/j.1538-7836.2003.00077.x
- 2002
- Rothkrantz-Kos, S., Schmitz, M. P. J., Bekers, O., Menheere, P. P. C. A., & van Dieijen-Visser, M. P. (2002). High-sensitivity C-reactive protein methods examined. Clinical Chemistry, 48(2), 359-362. https://doi.org/10.1093/CLINCHEM/48.2.359
- 2001
- Dhore, C. R., Cleutjens, J. P., Lutgens, E., Cleutjens, K. B., Geusens, P. P., Kitslaar, P. J., Tordoir, J. H., Spronk, H. M., Vermeer, C., & Daemen, M. J. (2001). Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. Arteriosclerosis Thrombosis and Vascular Biology, 21(12), 1998-2003. https://doi.org/10.1161/hq1201.100229
- Spronk, H. M., Soute, B. A., Schurgers, L. J., Cleutjens, J. P., Thijssen, H. H., De Mey, J. G., & Vermeer, C. (2001). Matrix Gla protein accumulates at the border of regions of calcification and normal tissue in the media of the arterial vessel wall. Biochemical and Biophysical Research Communications, 289(2), 485-90. https://doi.org/10.1006/bbrc.2001.5996
- Mousallem, M., Spronk, H. M., Sacy, R., Hakime, N., & Soute, B. A. (2001). Congenital combined deficiencies of all vitamin K-dependent coagulation factors. Thrombosis and Haemostasis, 86(5), 1334-1336. https://doi.org/10.1055/s-0037-1616072
- Farzaneh-Far, A., Davies, J. D., Braam, L. A., Spronk, H. M., Proudfoot, D., Chan, S. W., O'Shaughnessy, K. M., Weissberg, P. L., Vermeer, C., & Shanahan, C. M. (2001). A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels. Journal of Biological Chemistry, 276(35), 32466-73. https://doi.org/10.1074/jbc.M104909200
- Sere, KM., Janssen, MP., Willems, GM., Tans, G., Rosing, J., & Hackeng, TM. (2001). Purified protein S contains multimeric forms with increased APC-independent anticoagulant activity. Biochemistry, 40(30), 8852-8860. https://doi.org/10.1021/bi002500a
- Hackeng, T. M., Rosing, J., Spronk, H. M., & Vermeer, C. (2001). Total chemical synthesis of human matrix Gla protein. Protein Science, 10(4), 864-70. https://doi.org/10.1110/ps.44701
- Schurgers, L. J., Dissel, P. E., Spronk, H. M., Soute, B. A., Dhore, C. R., Cleutjens, J. P., & Vermeer, C. (2001). Role of vitamin K and vitamin K-dependent proteins in vascular calcification. Zeitschrift fur Kardiologie, 90 Suppl 3, 57-63. https://doi.org/10.1007/s003920170043
- 2000
- Hackeng, TM., Fernandez, JA., Dawson, PE., Kent, SBH., & Griffin, JH. (2000). Chemical synthesis and spontaneous folding of a multidomain protein: Anticoagulant microprotein S. Proceedings of the National Academy of Sciences of the United States of America, 97(26), 14074-14078. https://doi.org/10.1073/pnas.260239797
- Spronk, H. M., Farah, R. A., Buchanan, G. R., Vermeer, C., & Soute, B. A. (2000). Novel mutation in the gamma-glutamyl carboxylase gene resulting in congenital combined deficiency of all vitamin K-dependent blood coagulation factors. Blood, 96(10), 3650-3652. https://doi.org/10.1182/blood.V96.10.3650
- Hackeng, TM., Yegneswaran, S., Johnson, AE., & Griffin, JH. (2000). Conformational changes in activated protein C caused by binding of the first epidermal growth factor-like module of protein S. Biochemical Journal, 349, 757-764. https://doi.org/10.1042/bj3490757
- Braam, L. A., Dissel, P., Gijsbers, B. L., Spronk, H. M., Hamulyák, K., Soute, B. A., Debie, W., & Vermeer, C. (2000). Assay for human matrix gla protein in serum: potential applications in the cardiovascular field. Arteriosclerosis Thrombosis and Vascular Biology, 20(5), 1257-61. https://doi.org/10.1161/01.atv.20.5.1257
- Marx, PF., Hackeng, TM., Dawson, PE., Griffin, JH., Meijers, JCM., & Bouma, BN. (2000). Inactivation of active thrombin-activable fibrinolysis inhibitor takes place by a process that involves conformational instability rather than proteolytic cleavage. Journal of Biological Chemistry, 275(17), 12410-12415. https://doi.org/10.1074/jbc.275.17.12410
- Fernandez, JA., Kojima, K., Petaja, J., Hackeng, TM., & Griffin, JH. (2000). Cardiolipin enhances protein C pathway anticoagulant activity. Blood Cells Molecules and Diseases, 26(2), 115-123. https://doi.org/10.1006/bcmd.2000.0285
- Deguchi, H., Fernandez, JA., Hackeng, TM., Banka, CL., & Griffin, JH. (2000). Cardiolipin is a normal component of human plasma lipoproteins. Proceedings of the National Academy of Sciences of the United States of America, 97(4), 1743-1748. https://doi.org/10.1073/pnas.97.4.1743
- 1999
- Hackeng, TM., Griffin, JH., & Dawson, PE. (1999). Protein synthesis by native chemical ligation: Expanded scope by using straightforward methodology. Proceedings of the National Academy of Sciences of the United States of America, 96(18), 10068-10073. https://doi.org/10.1073/pnas.96.18.10068
- Curvers, J., Christella, M., Thomassen, L. G. D., Nicolaes, G. A. F., van Oerle, R., Hamulyak, K., Hemker, H. C., Tans, G., & Rosing, J. (1999). Acquired APC resistance and oral contraceptives: Differences between two functional tests. British Journal of Haematology, 105(1), 88-94. https://doi.org/10.1111/j.1365-2141.1999.01302.x
- 1997
- Wang, LL., Zoppe, M., Hackeng, TM., Griffin, JH., Lee, K.-F., & Verma, IM. (1997). A factor IX-deficient mouse model for hemophilia B gene therapy. Proceedings of the National Academy of Sciences of the United States of America, 94(21), 11563-11566. https://doi.org/10.1073/pnas.94.21.11563
- Wielders, S., Mukherjee, M., Michiels, J., Rijkers, D. T. S., Cambus, J.-P., Knebel, R. W. C., Kakkar, V., Hemker, H. C., & Beguin, S. (1997). The routine determination of the endogenous thrombin potential, first results in different forms of hyper- and hypocoagulability. Thrombosis and Haemostasis, 77(4), 629-636. https://doi.org/10.1055/s-0038-1656024
- Rosing, J., Tans, G., Nicolaes, G. A. F., Thomassen, M. C. G. L. D., van Oerle, R., van der Ploeg, P. M. E. N., Heijnen, P., Hamulyak, K., & Hemker, H. C. (1997). Oral contraceptives and venous thrombosis: Different sensitives to activated protein C in women using second-and third-generation oral contraceptives. British Journal of Haematology, 97(1), 233-238. https://doi.org/10.1046/j.1365-2141.1997.192707.x
- 1995
- KOPPELMAN, SJ., HACKENG, TM., SIXMA, JJ., & BOUMA, BN. (1995). INHIBITION OF THE INTRINSIC-FACTOR-X ACTIVATING COMPLEX BY PROTEIN-S - EVIDENCE FOR A SPECIFIC BINDING OF PROTEIN-S TO FACTOR-VIII. Blood, 86(3), 1062-1071. https://doi.org/10.1182/blood.V86.3.1062.1062
- VANTVEER, C., HACKENG, TM., BIESBROECK, D., SIXMA, JJ., & BOUMA, BN. (1995). INCREASED PROTHROMBIN ACTIVATION IN PROTEIN S-DEFICIENT PLASMA UNDER FLOW CONDITIONS ON ENDOTHELIAL-CELL MATRIX - AN INDEPENDENT ANTICOAGULANT FUNCTION OF PROTEIN-S IN PLASMA. Blood, 85(7), 1815-1821. https://doi.org/10.1182/blood.V85.7.1815.bloodjournal8571815
- 1994
- VANTVEER, C., HACKENG, TM., DELAHAYE, C., SIXMA, JJ., & BOUMA, BN. (1994). ACTIVATED FACTOR-X AND THROMBIN FORMATION TRIGGERED BY TISSUE FACTOR ON ENDOTHELIAL-CELL MATRIX IN A FLOW MODEL - EFFECT OF THE TISSUE FACTOR PATHWAY INHIBITOR. Blood, 84(4), 1132-1142. https://doi.org/10.1182/blood.V84.4.1132.1132
- 1993
- Hemker, H. C., Wielders, S., Kessels, H., & Beguin, S. (1993). Continuous registration of thrombin generation in plasma: Its use for the determination of the thrombin potential. Thrombosis and Haemostasis, 70(4), 617-624. https://doi.org/10.1055/s-0038-1649638
- 1992
- Beguin, S., Wielders, S., Lormeau, J. C., & Hemker, H. C. (1992). The Mode of Action of CY216 and CY222 in Plasma. Thrombosis and Haemostasis, 67(1), 33-41. https://doi.org/10.1055/s-0038-1648375
- 1991
- Hemker, H. C., Beguin, S., Bendetowicz, A. V., & Wielders, S. (1991). Determination of the levels of unfractionated and low-molecular-weight heparins in plasma: Their effect on thrombin-mediated feedback reactions in vivo. Haemostasis, 21(4), 258-272. https://doi.org/10.1159/000216235
- Yukelson, L. Y., Tans, G., Thomassen, M. C. L. G. D., Hemker, H. C., & Rosing, J. (1991). Procoagulant activities in venoms from Central Asian snakes. Toxicon, 29(4-5), 491-502. https://doi.org/10.1016/0041-0101(91)90023-K




