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Ramakers, I. H. G. B., Visser, P. J., Aalten, P., Bekers, O., Sleegers, K., van Broeckhoven, C. L., Jolles, J., & Verhey, F. R. (2008). The association between APOE genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and Alzheimer pathology. Dementia and Geriatric Cognitive Disorders, 26(2), 101-8. https://doi.org/10.1159/000144072

Cranenburg, E. C., Vermeer, C., Koos, R., Boumans, M. L., Hackeng, T. M., Bouwman, F. G., Kwaijtaal, M., Brandenburg, V. M., Ketteler, M., & Schurgers, L. J. (2008). The circulating inactive form of matrix Gla Protein (ucMGP) as a biomarker for cardiovascular calcification. Journal of Vascular Research, 45(5), 427-36. https://doi.org/10.1159/000124863

Meex, S. J., van Vliet-Ostaptchouk, J. V., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Schalkwijk, C. G., Feskens, E. J. M., Blaak, E. E., Wijmenga, C., Hofker, M. H., Stehouwer, C. D., & de Bruin, T. W. (2008). Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: Association study in 2000 Dutch Caucasians. Molecular Genetics and Metabolism, 94(3), 352-355. https://doi.org/10.1016/j.ymgme.2008.03.011

Megens, R. T. A., Oude Egbrink, M. G. A., Cleutjens, J. P. M., Kuijpers, M. J. E., Schiffers, P. H. M., Merkx, M., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2007). Imaging collagen in intact viable healthy and atherosclerotic arteries using fluorescently labeled CNA35 and two-photon laser scanning microscopy. Molecular Imaging, 6(4), 247-60. https://doi.org/10.2310/7290.2007.00021

Dielis, A. W. J. H., Smid, M., Spronk, H. M. H., Houben, A. J. H. M., Hamulyák, K., Kroon, A. A., Ten Cate, H., & de Leeuw, P. W. (2007). Changes in fibrinolytic activity after angiotensin II receptor blockade in therapy-resistant hypertensive patients. Journal of Thrombosis and Haemostasis, 5(7), 1509-15. https://doi.org/10.1111/j.1538-7836.2007.02577.x

Aerts, H. J. W. L., Dubois, L., Hackeng, T. M., Straathof, R., Chiu, R. K., Lieuwes, N. G., Jutten, B., Weppler, S. A., Lammering, G., Wouters, B. G., & Lambin, P. (2007). Development and evaluation of a cetuximab-based imaging probe to target EGFR and EGFRvIII. Radiotherapy and Oncology, 83(3), 326-332. https://doi.org/10.1016/j.radonc.2007.04.030

Koenen, R. R., von Hundelshausen, P., & Weber, C. (2007). Inflammatory blues turns velvet skin into rawhide: monocyte rolling on modified endothelial PSGL-1. Arteriosclerosis Thrombosis and Vascular Biology, 27(5), 990-2. https://doi.org/10.1161/ATVBAHA.107.141689

Bernhagen, J., Krohn, R., Lue, H., Gregory, J. L., Zernecke, A., Koenen, R. R., Dewor, M., Georgiev, I., Schober, A., Leng, L., Kooistra, T., Fingerle-Rowson, G., Ghezzi, P., Kleemann, R., McColl, S. R., Bucala, R., Hickey, M. J., & Weber, C. (2007). MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nature Medicine, 13(5), 587-96. https://doi.org/10.1038/nm1567

Meex, S. J., van Greevenbroek, M. M. J., Ayoubi, T. A., Vlietinck, R., van Vliet-Ostaptchouk, J. V., Hofker, M. H., Vermeulen, V. M., Schalkwijk, C. G., Feskens, E. J., Boer, J. M., Stehouwer, C. D., van der Kallen, C. J. H., & de Bruin, T. W. (2007). Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians. Journal of Clinical Endocrinology & Metabolism, 92(7), 2720-2725. https://doi.org/10.1210/jc.2006-2280

op den Buijsch, R. A., van de Plas, A., Stolk, L. M. L., Christiaans, M. H., van Hooff, J. P., Undre, N. A., van Dieijen-Visser, M. P., & Bekers, O. (2007). Evaluation of limited sampling strategies for tacrolimus. European Journal of Clinical Pharmacology, 63(11), 1039-1044. https://doi.org/10.1007/s00228-007-0354-9

Veltkamp, M., Wijnen, P. A. H. M., Moorsel, C. H., Rijkers, G. T., Ruven, H. J., Heron, M., Bekers, O., Claessen, A. M., Drent, M., Van den Bosch, J. M. M., & Grutters, J. C. (2007). Linkage between Toll-like receptor (TLR) 2 promotor and intron polymorphisms: functional effects and relevance to sarcoidosis.Clinical and Experimental Immunology, 149(3), 453-462. https://doi.org/10.1111/j.1365-2249.2007.03428.x

Wijnen, P. A. H. M., Op den Buisch, R., Drent, M., Kuipers, P. M. J. C., Neefs, C., Bast, A., Bekers, O., & Koek, G. H. (2007). Review article: The prevalence and clinical relevance of cytochrome P450 polymorphisms.Alimentary Pharmacology & Therapeutics, 26(2), 211-219. https://doi.org/10.1111/j.1365-2036.2007.03490.x

op den Buijsch, R. A., Christiaans, M. H., Stolk, L. M. L., de Vries, J. E., Cheung, C. Y., Undre, N. A., van Hooff, J. P., van Dieijen-Visser, M. P., & Bekers, O. (2007). Tacrolimus pharmacokinetics and pharmacogenetics: influence of adenosine triphosphate-binding cassette B1 (ABCB1) and cytochrome (CYP) 3A polymorphisms. Fundamental & Clinical Pharmacology, 21(4), 427-435. https://doi.org/10.1111/j.1472-8206.2007.00504.x

Llerena, A., Michel, G., Jeannesson, E., Wong, S., Manolopoulos, V. G., Hockett, R. D., Boubekeur, K., Siest, G., Beaune, P., Haefliger, C., Arnold, H. P., Junien, C., Petrovic, N., Molloy, R., Bekers, O., Donnelly, C., Arens, H. J., Kaput, J., & McComb, J. (2007). Third Santorini conference pharmacogenomics workshop report: "Pharmacogenomics at the crossroads: what else than good science will be needed for the field to become part of Personalized Medicine?". Clinical Chemistry and Laboratory Medicine, 45(7), 843-850. https://doi.org/10.1515/CCLM.2007.182

Prinzen, L., Miserus, R.-J. J. H. M., Dirksen, A., Hackeng, T. M., Deckers, N., Bitsch, N. J., Megens, R. T. A., Douma, K., Heemskerk, J. W., Kooi, M. E., Frederik, P. M., Slaaf, D. W., van Zandvoort, M. A. M. J., & Reutelingsperger, C. P. M. (2007). Optical and magnetic resonance imaging of cell death and platelet activation using annexin A5-functionalized quantum dots. Nano Letters, 7(1), 93-100. https://doi.org/10.1021/nl062226r

Langereis, S., Dirksen, A., Hackeng, T. M., van Genderen, M. H. P., & Meijer, E. W. (2007). Dendrimers and magnetic resonance imaging. New Journal of Chemistry, 31(7), 1152-1160. https://doi.org/10.1039/b616960k

Dirksen, A., Dirksen, S., Hackeng, T. M., & Dawson, P. E. (2006). Nucleophilic catalysis of hydrazone formation and transimination: Implications for dynamic covalent chemistry. Journal of the American Chemical Society, 128(49), 15602-15603. https://doi.org/10.1021/ja067189k

Buehler, A., van Zandvoort, M. A. M. J., Stelt, B. J., Hackeng, T. M., Schrans-Stassen, B. H. G. J., Bennaghmouch, A., Hofstra, L., Cleutjens, J. P. M., Duijvestijn, A., Smeets, M. B., de Kleijn, D. P. V., Post, M. J., & de Muinck, E. D. (2006). cNGR: a novel homing sequence for CD13/APN targeted molecular imaging of murine cardiac angiogenesis in vivo. Arteriosclerosis Thrombosis and Vascular Biology, 26(12), 2681-7. https://doi.org/10.1161/01.ATV.0000245807.65714.0b

Nicolaes, G. A. F., Hackeng, T. M., Segers, K., & Rosing, J. (2006). A structural model of the SHBG domain of human variant protein S Heerlen. Thrombosis and Haemostasis, 96(4), 538-540. https://doi.org/10.1160/TH06-07-0361

Spronk, H. M. H. (2006). Vitamin K epoxide reductase complex and vascular calcification: is this the important link between vitamin K and the arterial vessel wall?Circulation, 113(12), 1550-2. https://doi.org/10.1161/CIRCULATIONAHA.105.617167

Sommeijer, D. W., Hansen, H. R., van Oerle, R., Hamulyak, K., van Zanten, A. P., Meesters, E., Spronk, H. M. H., & ten Cate, H. (2006). Soluble tissue factor is a candidate marker for progression of microvascular disease in patients with Type 2 diabetes. Journal of Thrombosis and Haemostasis, 4(3), 574-80. https://doi.org/10.1111/j.1538-7836.2005.01763.x

Hackeng, TM., Sere, KM., Tans, G., & Rosing, J. (2006). Protein S stimulates inhibition of the tissue factor pathway by tissue factor pathway inhibitor. Proceedings of the National Academy of Sciences of the United States of America, 103(9), 3106-3111. https://doi.org/10.1073/pnas.0504240103

de Waard, V., Hansen, H. R., Spronk, H. H. M., Timmerman, J. J., Pannekoek, H., Florquin, S., Reitsma, P. H., & ten Cate, H. (2006). Differential expression of tissue factor mRNA and protein expression in murine sepsis. The role of the granulocyte revisited. Thrombosis and Haemostasis, 95(2), 348-53. https://doi.org/10.1160/TH05-07-0512

Dirksen, A., Hackeng, T. M., & Dawson, P. E. (2006). Nucleophilic catalysis of oxime ligation. Angewandte Chemie-International Edition, 45(45), 7581-7584. https://doi.org/10.1002/anie.200602877

Dirksen, A., Meijer, EW., Adriaens, W., & Hackeng, TM. (2006). Strategy for the synthesis of multivalent peptide-based nonsymmetric dendrimers by native chemical ligation. Chemical Communications, (15), 1667-1669. https://doi.org/10.1039/b600286b

Dielis, A. W. J. H., Smid, M., Spronk, H. M. H., Hamulyak, K., Kroon, A. A., ten Cate, H., & de Leeuw, P. W. (2005). The prothrombotic paradox of hypertension: role of the renin-angiotensin and kallikrein-kinin systems. Hypertension, 46(6), 1236-42. https://doi.org/10.1161/01.HYP.0000193538.20705.23

Denis, CV., Roberts, SJ., Hackeng, TM., & Lenting, PJ. (2005). In vivo clearance of human protein S in a mouse model - Influence of c4b-binding protein and the Heerlen polymorphism. Arteriosclerosis Thrombosis and Vascular Biology, 25(10), 2209-2215. https://doi.org/10.1161/01.ATV.0000181760.55269.6b

Hackeng, TM., Sere, KM., & Rosing, J. (2005). Misconceptions about protein-S multimers - Response. Blood, 106(5), 1884-1885. https://doi.org/10.1182/blood-2004-12-4706

Sommeijer, D. W., van Oerle, R., Reitsma, P. H., Timmerman, J. J., Meijers, J. C. M., Spronk, H. M. H., & ten Cate, H. (2005). Analysis of blood coagulation in mice: pre-analytical conditions and evaluation of a home-made assay for thrombin-antithrombin complexes. Thrombosis Journal, 3, Article 12. https://doi.org/10.1186/1477-9560-3-12

Keuren, JFW., Wielders, SJH., Ulrichts, H., Hackeng, T., Heemskerk, JWM., Deckmyn, H., Bevers, EM., & Lindhout, T. (2005). Synergistic effect of thrombin on collagen-induced platelet procoagulant activity is mediated through protease-activated receptor-1. Arteriosclerosis Thrombosis and Vascular Biology, 25(7), 1499-1505. https://doi.org/10.1161/01.ATV.0000167526.31611.f6

Langereis, S., Dirksen, A., De Waal, BFM., Van Genderen, MHP., De Lussanet, QG., Hackeng, TM., & Meijer, EW. (2005). Solid-phase synthesis of a cyclic NGR-functionalized Gd(III)DTPA complex. European Journal of Organic Chemistry, 2005(12), 2534-2538. https://doi.org/10.1002/ejoc.200500045

Koenen, RR., Thomassen, MCLGD., Tans, G., Rosing, J., & Hackeng, TM. (2005). Effect of oral contraceptives on the anticoagulant activity of protein S in plasma. Thrombosis and Haemostasis, 93(5), 853-859. https://doi.org/10.1160/TH04-11-0762

Ravassa, S., Bennaghmouch, A., Kenis, H., Lindhout, T., Hackeng, T., Narula, J., Hofstra, L., & Reutelingsperger, C. (2005). Annexin A5 down-regulates surface expression of tissue factor. Journal of Biological Chemistry, 280(7), 6028-6035. https://doi.org/10.1074/jbc.M411710200

von Hundelshausen, P., Koenen, RR., Sack, M., Mause, SF., Adriaens, W., Proudfoot, AEI., Hackeng, TM., & Weber, C. (2005). Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium. Blood, 105(3), 924-930. https://doi.org/10.1182/blood-2004-06-2475

Fischer, M. A. J. G., Gransier, T. J., Beckers, L. M., Bekers, O., Bast, A., & Haenen, G. R. (2005). Determination of the antioxidant capacity in blood. Clinical Chemistry and Laboratory Medicine, 43(7), 735-740. https://doi.org/10.1515/CCLM.2005.125

op den Buijsch, R. A., de Vries, J. E., Loots, W. J., Landt, O., Wijnen, P. A. H. M., van Dieijen-Visser, M. P., & Bekers, O. (2005). Genotyping of the PXR A11156C polymorphism with locked nucleic acid containing fluorogenic probes. Pharmacogenomics, 5(2), 72-74. https://doi.org/10.1038/sj.tpj.6500299

Hackeng, TM. (2005). Gla glances at proteins. Blood, 105(1), 1-2. https://doi.org/10.1182/blood-2004-10-3874

Slofstra, S. H., van 't Veer, C., Buurman, W. A., Reitsma, P. H., ten Cate, H., & Spek, C. A. (2005). Low molecular weight heparin attenuates multiple organ failure in a murine model of disseminated intravascular coagulation. Critical Care Medicine, 33(6), 1365-1370. https://doi.org/10.1097/01.CCM.0000166370.94927.B6

Henry, R. M. A., Kamp, O., Kostense, P. J., Spijkerman, A. M., Dekker, J. M., Nijpels, G., Heine, R. J., Bouter, L. M., & Stehouwer, C. D. A. (2005). Mild renal insufficiency is associated with increased left ventricular mass in men but not in women an arterial-stiffness-related phenomenon - The Hoorn Study. Kidney International, 68, 673-679. https://doi.org/10.1111/j.1523-1755.2005.00445.x

van der Meijden, P. E. J., Feijge, M. A. H., Giesen, P. L. A., Huijberts, M. S. P., van Raak, L. P., & Heemskerk, J. W. (2005). Platelet P2Y12 receptors enhance signalling towards procoagulant activity and thrombin generation. A study with healthy subjects and patients at thrombotic risk. Thrombosis and Haemostasis, 93(6), 1128-1136. https://doi.org/10.1160/TH04-09-0597

Beerenhout, C. H., Luik, A. J., Jeuken Mertens, S. G., Bekers, O., Menheere, P. P., Hover, L., Klaassen, L., van der Sande, F. M., Cheriex, E. C., Meert, N., Leunissen, K. M. L., & Kooman, J. P. (2005). Pre-dilution on-line haemofiltration vs low-flux haemodialysis: a randomized prospective study. Nephrology Dialysis Transplantation, 20(6), 1155-1163. https://doi.org/10.1093/ndt/gfh775

op den Buijsch, R. A., Wijnen, P. A. H. M., van Dieijen-Visser, M. P., de Vries, J. E., & Bekers, O. (2005). Rapid genotyping of the OATP1B1 polymorphisms A388G and T521C with real-time PCR FRET assays. Pharmacogenomics, 6(4), 393-397. https://doi.org/10.1517/14622416.6.4.393

Spijkerman, A. M., Smulders, Y. M., Kostense, P. J., Henry, R. M. A., Becker, A., Teerlink, T., Jakobs, C., Dekker, J. M., Nijpels, G., Heine, R. J., Bouter, L. M., & Stehouwer, C. D. (2005). S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study. Arteriosclerosis Thrombosis and Vascular Biology, 25(4), 778-784. https://doi.org/10.1161/01.ATV.0000157981.57694.d2