Publications
- 2025
- Metzner, A., Willems, S., Borof, K., Breithardt, G., Camm, A. J., Crijns, H. J. G. M., Eckardt, L., Fabritz, L., Gessler, N., Goette, A., Reissmann, B., Schnabel, R. B., Schotten, U., Zapf, A., Rillig, A., & Kirchhof, P. (2025). Diabetes and Obesity and Treatment Effect of Early Rhythm Control vs Usual Care in Patients With Atrial Fibrillation: A Secondary Analysis of the EAST-AFNET 4 Randomized Clinical Trial. JAMA Cardiology, 10(9), 932-941. https://doi.org/10.1001/jamacardio.2025.2374
- Hereijgers, M. J. M., van der Velden, R. M. J., Reinders, L. G., Weerts, Z., Kuijpers, S., Luermans, J., Chaldoupi, S. M., Vernooy, K., Hermans, A. N. L., Posthuma, R., Franssen, F. M. E., Linz, D., & Simons, S. O. (2025). Feasibility and diagnostic yield of a photoplethysmography-based arrhythmia screening and integrated management pathway in a COPD outpatient clinic. ERJ Open Research, 11(5), Article 01192-2024. https://doi.org/10.1183/23120541.01192-2024
- Schalla, S., Wildberger, J. E., Ramaekers, M. J. F. G., Mihl, C., McDermott, M. C., Stammen, L., Vernooy, K., & Flohr, T. G. (2025). Imaging of Cardiovascular Implantable Electronic Device Leads With Photon-Counting Detector Computed Tomography. Investigative Radiology, 60(9), 616-625. https://doi.org/10.1097/RLI.0000000000001177
- Joza, J., van Koll, J., Ramalingam, V., Tai, P., Essebag, V., Hadjis, T. A., Lankveld, T. A. R., van Stipdonk, A. M. W., Rijks, J. H. J., Nguyên, U. C., Luermans, J., Verma, A., & Vernooy, K. (2025). Implementation of lead V8 as a simple non-invasive tool to improve patient selection in cardiac resynchronization therapy and guide left ventricular lead placement. EP Europace, 27(9), Article euaf194 . https://doi.org/10.1093/europace/euaf194
- Martens, B., van der Meulen, L. R., Crawley, R. J., van Cauteren, Y. J. M., Smulders, M. W., Streukens, S., Hendriks, B. M. F., Houben, I. P. L., Gommers, S., Frey, S. M., Brandts, L., Wildberger, J. E., Chiribiri, A., & Holtackers, R. J. (2025). Influence of Reader Expertise on Myocardial Infarction Detection: A Comparative Study of Dark-Blood and Bright-Blood Late Gadolinium Enhancement MRI. Investigative Radiology, 60(9), 561-568. https://doi.org/10.1097/RLI.0000000000001161
- Kawczynski, M. J., Gilbers, M. D., Winters, J., Maesen, B., Isaacs, A., Linz, D., Rienstra, M., van Gelder, I., Maessen, J. G., Bidar, E., & Schotten, U. (2025). Right atrial endomysial fibrosis is associated with increased postoperative atrial fibrillation burden during 2.5 years of continuous rhythm monitoring after cardiac surgery including atrial arrhythmia surgery: RACE V Tissue Bank Study. EP Europace, 27(9), Article euaf207. https://doi.org/10.1093/europace/euaf207
- Swinnen, B., Kawczynski, M. J., Mingels, A. M. A., Wildberger, J. E., Mihl, C., Smulders, M. W., Maessen, J. G., Gollmann-Tepeköylü, C., & Heuts, S. (2025). The prognostic impact of prevailing definitions of periprocedural myocardial infarction in patients undergoing coronary artery bypass grafting. European heart journal - Quality of care & clinical outcomes, 11(6), 847-856. https://doi.org/10.1093/ehjqcco/qcaf043
- van Ochten, M., El Fathi, W., Bovee, E. M. E., Spaanderman, M. E. A., Hooijmans, C. R., & van Drongelen, J. (2025). The renal baroreflex: A systematic review and meta-analysis in healthy and hypertensive animals. Physiological Reports, 13(17), Article e70547. https://doi.org/10.14814/phy2.70547
- Holtackers, R. J., Varga-Szemes, A., & Smulders, M. W. (2025). Editorial for “Improved and Automated Detection of Papillary Muscle Infarction Using Joint Bright- and Black-Blood Late Gadolinium Enhancement MRI”. Journal of Magnetic Resonance Imaging, 62(3), 840-841. https://doi.org/10.1002/jmri.29794
- Mizner, J., Beela, A., Linkova, H., Vesela, J., Sussenbek, O., Stros, P., Smisek, R., Jurak, P., Leinveber, P., Lipoldova, J., Nagy, A., Waldauf, P., Lumens, J., Vernooy, K., Prinzen, F., & Curila, K. (2025). Electrical and mechanical interventricular dyssynchrony coupling in patients with bradycardia: A UHF-ECG validation trial. Heart Rhythm, 22(9), 2382-2390. https://doi.org/10.1016/j.hrthm.2025.02.031
- Sandgren, E., Betz, K., Gawalko, M., Hermans, A., Habibi, Z., Verhaert, D., Philippens, S., Vorstermans, B., Uijl, D. D., Chaldoupi, S.-M., Luermans, J., Lankveld, T., Schotten, U., Vernooy, K., & Linz, D. (2025). Feasibility of repeated on-demand smartphone app-based approximation of time spent with atrial fibrillation and symptoms in patients after catheter ablation: Data from the ISOLATION study. Heart Rhythm, 22(9), 2269-2276. https://doi.org/10.1016/j.hrthm.2025.03.165
- Osman, H., Schlettert, C., Materzok, D., Akin, M., Abumayyaleh, M., Akin, I., Mügge, A., Aweimer, A., Hamdani, N., & El-Battrawy, I. (2025). Impact of smoking in MINOCA patients. European Journal of Clinical Investigation, 55(9), Article e70054. https://doi.org/10.1111/eci.70054
- Romeo, J. L., Vriesendorp, P. A., Gerritsen, K., Nader, M., Mahtab, E., Maessen, J. G., van 't Hof, A. W. J., Gollmann-Tepeköylü, C., van Rosmalen, F., van der Horst, I. C. C., Mingels, A. M. A., & Heuts, S. (2025). Modeling creatine-kinase MB concentrations following coronary artery bypass grafting. Journal of Thoracic and Cardiovascular Surgery, 170(3), 752-760.e3. https://doi.org/10.1016/j.jtcvs.2024.08.019
- Van den Eynde, M. D. G., van der Bruggen, M. M., Houben, A. J. H. M., Reesink, K. D., Spronck, B., Delhaas, T., Scheijen, J. J. L. J. M., Miyata, T., & Schalkwijk, C. G. (2025). Pyridoxamine does not reduce arterial stiffness in an 8-week randomized double-blind placebo-controlled intervention trial with abdominally obese individuals. Diabetes Obesity & Metabolism, 27(9), 5332-5336. https://doi.org/10.1111/dom.16524
- Costantino, S., Mohammed, S., Mengozzi, A., Duranti, E., Delfine, V., Geiger, M. A., Hamdani, N., Taddei, S., Masi, S., Virdis, A., & Paneni, F. (2025). Targeting the Epigenetic Remodeler GCN5 Prevents Vascular Oxidative Stress and Endothelial Dysfunction in Obesity: Insights in Patients with Cardiometabolic Disease. High Blood Pressure & Cardiovascular Prevention, 32(5), 577-589. https://doi.org/10.1007/s40292-025-00739-4
- Pustjens, T. F. S., Veenstra, L., Camaro, C., Ruiters, A. W., Lux, Á., Ruzsa, Z., Piroth, Z., Ilhan, M., Vainer, J., Gho, B., Winkler, P. J. C., Stein, M., Theunissen, R. A. L. J., Kala, P., Polad, J., Berta, B., Gabrio, A., van Royen, N., van 't Hof, A. W. J., & Rasoul, S. (2025). Fractional Flow Reserve-Guided Complete vs Culprit-Only Revascularization in Non-ST-Elevation Myocardial Infarction and Multivessel Disease: The SLIM Randomized Clinical Trial. JAMA-Journal of the American Medical Association, 334(18), 1628-1637. https://doi.org/10.1001/jama.2025.16189
- Szabo, B. R., Stein, J., Savchenko, A., Hutschalik, T., Van Nieuwerburgh, F., Meese, T., Kosmidis, G., Volders, P. G. A., & Matsa, E. (2025). Integral approach to organelle profiling in human iPSC-derived cardiomyocytes enhances in vitro cardiac safety classification of known cardiotoxic compounds. Frontiers in Toxicology, 7, Article 1644119. https://doi.org/10.3389/ftox.2025.1644119
- Akin, I., Hamdani, N., & El-Battrawy, I. (2025). Multimodal approaches for targeted treatment of heart failure. European Heart Journal, 46(31), 3122-3123. https://doi.org/10.1093/eurheartj/ehaf156
- Isaksen, J. L., Linz, D., & Kanters, J. K. (2025). Clinically useful evaluation of reconstruction techniques and use of Einthoven's Law. Journal of Electrocardiology, 92, Article 154090. https://doi.org/10.1016/j.jelectrocard.2025.154090
- van Mierlo, R., Scheenstra, B., Verbeek, J., Bruninx, A., Kalendralis, P., Bermejo, I., Dekker, A., van 't Hof, A., Spreeuwenberg, M., & Hochstenbach, L. (2025). Optimizing Cardiovascular Risk Management in Primary Care Using a Personalized eCoach Solution Enhanced by an Artificial Intelligence-Driven Clinical Prediction Model: Protocol from the Coronary Artery Disease Risk Estimation and Early Detection Consortium. JMIR Research Protocols, 14, Article e66068. https://doi.org/10.2196/66068
- Betti, M., Streukens, S. A. F., Kats, S., Maesen, B., Vainer, J., Theunissen, R. A. L. J., van ‘t Hof, A. W. J., & Vriesendorp, P. A. (2025). Mitral Transcatheter Edge-to-Edge Repair for Anterior Leaflet Flail Induced by Transapical Transcatheter Aortic Valve Replacement. JACC. Case reports, 30(22), Article 104653. https://doi.org/10.1016/j.jaccas.2025.104653
- Merino, J. L., Tamargo, J., Blomström-Lundqvist, C., Boriani, G., Crijns, H. J. G. M., Dobrev, D., Goette, A., Hohnloser, S. H., Naccarelli, G. V., Reiffel, J. A., Tfelt-Hansen, J., Martínez Cossiani, M., & Camm, A. J. (2025). Practical Compendium of Antiarrhythmic Drugs: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology. EP Europace, 27(8), Article euaf076. https://doi.org/10.1093/europace/euaf076
- Rivera, S., Ricapito, M. D. L. P., Ronderos, R., & Volders, P. G. A. (2025). Anatomical Determinants of Papillary Muscle Arrhythmias in Apparently Normal Hearts. Arrhythmia & Electrophysiology Review, 14, Article e16. https://doi.org/10.15420/aer.2025.10
- van Cauteren, Y. J. M., Lemmens, M. J. D. K., Bekkers, S. C. A. M., Kietselaer, B. L. J. H., Heijman, J., Theunissen, R. A. L. J., Rahel, B., Voorn, T., van Kuijk, S. M. J., Nijveldt, R., Vernooy, K., Wildberger, J. E., Mihl, C., & Smulders, M. W. (2025). Computed tomography angiography in the diagnosis of non-ST-elevation myocardial infarction: redefining our first line of defense. IJC Heart and Vasculature, 59, Article 101690. https://doi.org/10.1016/j.ijcha.2025.101690
- Janssen, E. B. N. J., Ghossein-Doha, C., Hooijschuur, M. C. E., Mulder, E. G., Schiffer, V. M. M. M., Alers, R.-J., Jorissen, L. M., Jansen, G. E., Kroon, A. A., Brugts, J. J., van 't Hof, A. W. J., & Spaanderman, M. E. A. (2025). Hypertension and cardiometabolic disorders appear 5-10 years earlier in women with pre-eclampsia. European Journal of Preventive Cardiology, 32(10), 822-832. https://doi.org/10.1093/eurjpc/zwaf187
- El-Battrawy, I., Hamdani, N., Abumayyaleh, M., & Akin, I. (2025). Intravenous iron in heart failure: still no prognostic impact, but questions remain. IJC Heart and Vasculature, 59, Article 101746. https://doi.org/10.1016/j.ijcha.2025.101746
- Hadaya, J., Boukens, B. J. D., Janse, M. J., Cha, S., Dajani, A.-H., Challita, R., Coronel, R., Ardell, J. L., Shivkumar, K., & Meijborg, V. M. F. (2025). Right stellate ganglion stimulation modulates arrhythmogenesis in acute left lateral ventricular ischaemia. Cardiovascular Research, 121(9), 1385-1391. https://doi.org/10.1093/cvr/cvaf121
- ter Bekke, R. M. A., van Rooij, T., Volders, P. G. A., & Hocini, M. (2025). Targeted ablation of the distal Purkinje-myocardium interface for premature ventricular complex-induced cardiomyopathy by delayed Purkinje conduction-induced re-excitation: a case report. European Heart Journal - Case Reports, 9(8), Article ytaf335. https://doi.org/10.1093/ehjcr/ytaf335
- Alers, R.-J., Ghossein-Doha, C., Brandt, Y., Kooi, M. E., Gerretsen, S. C., Jansen, J. F. A., Backes, W. H., van de Ven, V., Hurks, P. P. M., & Spaanderman, M. E. A. (2025). Associations of Metabolic Syndrome and Insulin Resistance With Attenuated Executive Function Post-Preeclampsia: A Nested Case-Control Study. Bjog-an International Journal of Obstetrics and Gynaecology, 132(9), 1269-1277. https://doi.org/10.1111/1471-0528.18186
- Farnir, F., Chaldoupi, S.-M., Hermans, B. J., Farnir, F., Habibi, Z., Jerltorp, K., Verhaert, D., Schotten, U., Maesen, B., Vernooy, K., Luermans, J., & Linz, D. (2025). A tailored substrate-based approach using focal pulsed field catheter ablation in patients with atrial fibrillation and advanced atrial substrate: Procedural data and 6-month success rates. Heart Rhythm, 22(8), 1957-1968. https://doi.org/10.1016/j.hrthm.2025.01.015
- Tönnis, T., Birkemeyer, R., Duncker, D., Eckardt, L., Groeschel, K., Linz, D., Meyer, C., Richter, S., Straube, F., Sultan, A., Wachter, R., Kirchhof, P., & Zylla, M. M. (2025). DGK-Positionspapier zum Umgang mit Device-detektiertem Vorhofflimmern (DDAF): Aus der Kommission für Klinische Kardiovaskuläre Medizin. Die Kardiologie, 19(4), 270-284. https://doi.org/10.1007/s12181-025-00750-y
- Oebel, S., Garcia, J. G., Arya, A., Jahnke, C., Paetsch, I., Loebe, S., Bode, K., ter Bekke, R. M. A., Vernooy, K., Dagres, N., Hindricks, G., & Darma, A. (2025). Late gadolinium enhancement imaging for the prediction of ventricular tachycardia ablation outcome. Journal of Interventional Cardiac Electrophysiology, 68(5), 1075-1085. https://doi.org/10.1007/s10840-025-02017-8
- Morcos, R., Vijayaraman, P., Cano, Ó., Zanon, F., Ponnusamy, S. S., Herweg, B., Sharma, P. S., Jastrzebski, M., Molina-Lerma, M., Whinnett, Z. I., Vernooy, K., Zou, J., Nair, G. M., Pathak, R. K., Tung, R., Upadhyay, G. A., Curila, K., Chelu, M. G., & Ellenbogen, K. A. (2025). Left bundle branch area pacing compared with biventricular pacing for cardiac resynchronization therapy in patients with left ventricular ejection fraction ≤50%: Results from the International Collaborative LBBAP Study (I-CLAS). Heart Rhythm, 22(8), 2028-2037. https://doi.org/10.1016/j.hrthm.2025.04.005
- Prinzen, F. W. (2025). Left Ventricular Mechanics During Left Ventricular Septal Pacing are Similar to Those During Left Bundle Branch Pacing. JACC: Clinical Electrophysiology, 11(8), 1862-1865. https://doi.org/10.1016/j.jacep.2025.04.036
- Kawczynski, M. J., Gabrio, A., Maessen, J. G., van 't Hof, A. W. J., Brophy, J. M., Gollmann-Tepeköylü, C., Sardari Nia, P., Vriesendorp, P. A., & Heuts, S. (2025). Percutaneous coronary intervention with drug-eluting stents versus coronary bypass surgery for coronary artery disease: a Bayesian perspective. Journal of Thoracic and Cardiovascular Surgery, 170(2), 558-565.e10. https://doi.org/10.1016/j.jtcvs.2024.08.017
- Sciacca, V., Feldt, J., Rottner, L., Heeger, C.-H., Sohns, C., Reissmann, B., Saguner, A. M., Santoro, F., Tilz, R. R., Maurer, T., Rillig, A., Ouyang, F., Linz, D., Vernooy, K., Sommer, P., Sultan, A., Willems, S., Kuck, K.-H., Metzner, A., & Fink, T. (2025). Periprocedural Safety of Interventional Electrophysiological Procedures in Octogenarians and Nonagenarians. Journal of Cardiovascular Electrophysiology, 36(8), 1721-1732. https://doi.org/10.1111/jce.16689
- Duytschaever, M., Grimaldi, M., De Potter, T., Verma, A., Macle, L., Kautzner, J., Linz, D., Anic, A., Van Herendael, H., Rackauskas, G., Neuzil, P., Chun, J., Schmidt, B., Knecht, S., Almorad, A., Berte, B., Reddy, V. Y., & Vijgen, J. (2025). PVI With CF-Sensing Large-Tip Focal PFA Catheter With 3D Mapping for Paroxysmal AF: Omny-IRE 3-Month Results. JACC: Clinical Electrophysiology, 11(8), 1769-1782. https://doi.org/10.1016/j.jacep.2025.04.008
- Ren, H., Qin, Q., Dong, Q., Ainiwaer, A., Yuan, H., Zhu, H., Cao, Z., Chen, Y., Wesselius, A., Zeegers, M. P., Prinzen, F. W., Chen, L., Yu, E. Y.-W., Luo, H., & TREND Cohort Study Investigators (2025). Smartphone-Measured Heart Sounds for Atrial Fibrillation Screening in Community Populations. Circulation, 152(4), 283-285. https://doi.org/10.1161/CIRCULATIONAHA.125.073828
- Velt, M. J. H., van Gelder, I. C., Crijns, H. J. G. M., Rienstra, M., & Mulder, B. A. (2025). Duration of atrial fibrillation and cardiac biomarkers are associated with cardiovascular outcomes in early permanent atrial fibrillation: Data from the RACE II study. International Journal of Cardiology, 439, Article 133669. https://doi.org/10.1016/j.ijcard.2025.133669
- Olde Nordkamp, L. R. A., de Veld, J. A., Ghani, A., Kuschyk, J., Bonnemeier, H., Bode, K., Boersma, L. V. A., de Weger, A., de Jong, J. S. S. G., Jansen, W. P. J., Alings, M., Bijsterveld, N., El-Chami, M. F., Beukema, R. J., Vernooy, K., Philbert, B. T., Neuzil, P., Nordbeck, P., van Opstal, J. M., ... PRAETORIAN-XL Investigators (2025). Device-related Complications in Transvenous Versus Subcutaneous Defibrillator Therapy During Long-term Follow-up: the PRAETORIAN-XL Trial. Circulation, 152(3), 172-182. https://doi.org/10.1161/CIRCULATIONAHA.125.074576
- Clerx, M., Volders, P. G. A., & Mirams, G. R. (2025). Variability in reported midpoints of (in)activation of cardiac INa. Journal of General Physiology, 157(5), Article e202413621. https://doi.org/10.1085/jgp.202413621
- Ganizada, B. H., Reesink, K. D., Parikh, S., Saraber, P. J. M. H., Cleutjens, J. P., Isabella, A., Krebbekx, M. Q. E., Jaminon, A. M., Maassen, C. F. M., Ramaekers, M. J. F. G., Spronck, B., van der Laan, K., Koenen, R. R., Lorusso, R., Maessen, J. G., Bidar, E., & Schurgers, L. J. (2025). Loss of wall stress homeostasis in ascending thoracic aortic aneurysm: histomorphometric insights into patient variants. The Journal of Physiology, 603(14), 3899-3922. https://doi.org/10.1113/JP288734
- Pencheva, M. G., Berends, E., van der Laan, K. W. F., Giudici, A., Niessen, P., Scheijen, J. L. J. M., Vangrieken, P., Leenders, P., Delhaas, T., Caiment, F., Kutmon, M., Trujillo, F. M., Wouters, K., Foulquier, S., Spronck, B., Reesink, K. D., & Schalkwijk, C. G. (2025). Glyoxalase-1 overexpression attenuates arterial wall stiffening in diabetic mice. Cardiovascular Diabetology, 24(1), Article 283. https://doi.org/10.1186/s12933-025-02823-4
- Wong, L. Y., Torfs, T., Vanherle, S. J. V., Janssen, J., Claes, G. R. F., Stroeks, S. L. V. M., Willemars, M. M. A., Schianchi, F., Kapsokalyvas, D., Weltjens, E., Swinnen, A., Strzelecka, A., Krapels, I. P. C., Heymans, S. R. B., Glatz, J., van den Wijngaard, A., Brunner, H. G., Broers, J., Luiken, J. F. P., ... Nabben, M. (2025). Clinical and metabolic consequences of a historic pathogenic lamin A/C founder variant. Scientific Reports, 15(1), Article 23842. https://doi.org/10.1038/s41598-025-08495-0
- Akerman, E., Aston, D., Rog-Zielinska, E. A., Boland, B., Schotten, U., Verheule, S., Capel, R. A., & Burton, R. A. B. (2025). Atrial granules as acidic calcium stores in cardiomyocytes. European heart journal open, 5(4), Article oeaf083. https://doi.org/10.1093/ehjopen/oeaf083
- Bovenkerk, D. S. H., Janssen, C. E. W., Van den Heuvel, F. M. A., Joosten, I. B. T., Den Uijl, D., Van Engelen, B. G. M., Van Kuijk, S. M. J., Nijveldt, R., Evertz, R., Faber, C. G., Vernooy, K., & Bijvoet, G. P. (2025). Evaluation of echocardiography monitoring in myotonic dystrophy type 1 patients. Frontiers in Cardiovascular Medicine, 12, Article 1574885. https://doi.org/10.3389/fcvm.2025.1574885
- Rademaker, R., Cirkel, S., Omara, S., Dankers, F., Sramko, M., Solana Munoz, J., Kaya, Y. S., Ter Bekke, R., Schiappacasse, L., Teres, C., Verhoeven, K., Pruvot, E., Rasch, C., & Zeppenfeld, K. (2025). Excellent interobserver agreement and steep learning curve for target volume delineation for stereotactic arrhythmia radioablation using a commercial software. EP Europace, 27(7), Article euaf122. https://doi.org/10.1093/europace/euaf122
- Blok, M., den Ouden, B. L., Kuiper, M., Ophelders, D. R. M. G., Jongbloed, M. R. M., Zeemering, S., Jensen, B., van Hunnik, A., & Boukens, B. J. (2025). Functional conduction system mapping in sheep reveals Purkinje spikes in the free wall of the right ventricular outflow tract. Frontiers in physiology, 16, Article 1631426. https://doi.org/10.3389/fphys.2025.1631426
- Khan, M. S., Javaid, S. S., Mentz, R. J., Lindenfeld, J., Wu, H.-T., Prochaska, J. H., Johansen, J. B., Wild, P. S., Linz, D., Dinh, W., & Fudim, M. (2025). Heart rate variability in patients with cardiovascular diseases. Progress in Cardiovascular Diseases, 91, 67-79. https://doi.org/10.1016/j.pcad.2025.06.003
- Malgie, J., Wilde, M. I., Brunner-La Rocca, H.-P., Emans, M. E., De Boer, G. A., Siegers, C. E. P., van Stipdonk, A. M. W., Wardeh, A. J., Schaap, J., Sanders-van Wijk, S., van den Heuvel, M., Wierda, E., De Boer, R. A., Koudstaal, S., & Brugts, J. J. (2025). Newly diagnosed heart failure with reduced ejection fraction: timing, sequencing, and titration of guideline-recommended medical therapy. European Heart Journal, 46(25), 2394-2405. https://doi.org/10.1093/eurheartj/ehaf244




