Publications
- 2025
- Li, Y., Zhao, Z., Ainiwaer, A., Mei, D., Zhang, P., Prinzen, F. W., & Luo, H. (2025). Smartphone for heart sound measurement in hospital: feasibility and influencing factors. European Heart Journal - Digital Health, 6(3), 486-495. https://doi.org/10.1093/ehjdh/ztaf007
- Svennberg, E., Han, J. K., Caiani, E. G., Engelhardt, S., Ernst, S., Friedman, P., Garcia, R., Ghanbari, H., Hindricks, G., Man, S. H., Millet, J., Narayan, S. M., Ng, G. A., Noseworthy, P. A., Tjong, F. V. Y., Ramirez, J., Singh, J. P., Trayanova, N., Duncker, D., ... Zorzi, A. (2025). State of the Art of Artificial Intelligence in Clinical Electrophysiology in 2025: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), and the ESC Working Group on E-Cardiology. EP Europace, 27(5), Article euaf071. https://doi.org/10.1093/europace/euaf071
- Habibi, Z., Verhaert, D. V. M., Betz, K., Hermans, B. J. M., Winters, J., Philippens, S. A. M., Chaldoupi, S. M., Maesen, B., Maessen, J. G., Isaacs, A., Westra, S. W., Nijveldt, R., Gillet, L., Wienhues-Thelen, U. H., Koehler, M., Zeemering, S., Vernooy, K., Linz, D., & Schotten, U. (2025). Association of atrial fibrillation burden and clinical profile with blood biomarkers: Results from the ISOLATION Ablation Cohort. Heart Rhythm O2, 6(5), 661-670. https://doi.org/10.1016/j.hroo.2025.02.017
- Fink, T., Sciacca, V., Bannmann, K., Moersdorf, M., Beyer, S., Parlato, A., Guckel, D., El Hamriti, M., Khalaph, M., Braun, M., Didenko, M., Imnadze, G., Linz, D., Vernooy, K., Sommer, P., & Sohns, C. (2025). First Experience Using a Novel Variable Loop Catheter for Mapping and Pulsed Field Ablation of Atrial Fibrillation. Pacing and Clinical Electrophysiology, 48(5), 471-479. https://doi.org/10.1111/pace.15177
- Manninger, M., Lercher, I., Hermans, A. N. L., Isaksen, J. L., Prassl, A. J., Zirlik, A., Vernooy, K., Chaldoupi, S.-M., Luermans, J., Ter Bekke, R. M. A., Kanters, J. K., Plank, G., Scherr, D., Pock, T., & Linz, D. (2025). Machine-learning guided differentiation between photoplethysmography waveforms of supraventricular and ventricular origin. Computer Methods and Programs in Biomedicine, 267, Article 108798. https://doi.org/10.1016/j.cmpb.2025.108798
- Manetti, C. A., van Osta, N., Beela, A. S., Herbots, L., Prinzen, F. W., Delhaas, T., & Lumens, J. (2025). Impact of myocardial phenotype on optimal atrioventricular delay settings during biventricular and left bundle-branch pacing at rest and during exercise: insights from a virtual patient study. EP Europace, 27(4), Article euaf082. https://doi.org/10.1093/europace/euaf082
- Gottschlich, A., Grünmeier, R., Hoffmann, G. V., Nandi, S., Kavaka, V., Müller, P. J., Jobst, J., Oner, A., Kaiser, R., Gärtig, J., Piseddu, I., Frenz-Wiessner, S., Fairley, S. D., Schulz, H., Igl, V., Janert, T. A., Di Fina, L., Mulkers, M., Thomas, M., ... Kobold, S. (2025). Dissection of single-cell landscapes for the development of chimeric antigen receptor T cells in Hodgkin lymphoma. Blood, 145(14), 1536-1552. https://doi.org/10.1182/blood.2023022197
- Van Osta, N., Van Den Acker, G., Van Loon, T., Arts, T., Delhaas, T., & Lumens, J. (2025). Numerical accuracy of closed-loop steady state in a zero-dimensional cardiovascular model. Philosophical Transactions of the Royal Society A: mathematical Physical and Engineering Sciences, 383(2293), Article 20240208. https://doi.org/10.1098/rsta.2024.0208
- Giudici, A., Grillo, A., Scalise, F., Reesink, K. D., Delhaas, T., Salvi, P., Spronck, B., & Parati, G. (2025). Beat-to-beat variability of aortic pulse wave velocity: Implications for aortic stiffness measurements. Journal of Hypertension, 43(4), 589-597. Article 3935. https://doi.org/10.1097/HJH.0000000000003935
- Glikson, M., Burri, H., Abdin, A., Cano, O., Curila, K., De Pooter, J., Diaz, J. C., Drossart, I., Huang, W., Israel, C. W., Jastrzebski, M., Joza, J., Karvonen, J., Keene, D., Leclercq, C., Mullens, W., Pujol-Lopez, M., Rao, A., Vernooy, K., ... Michowitz, Y. (2025). European Society of Cardiology (ESC) clinical consensus statement on indications for conduction system pacing, with special contribution of the European Heart Rhythm Association of the ESC and endorsed by the Asia Pacific Heart Rhythm Society, the Canadian Heart Rhythm Society, the Heart Rhythm Society, and the Latin American Heart Rhythm Society. EP Europace, 27(4), Article euaf050. https://doi.org/10.1093/europace/euaf050
- Achten, A., Weerts, J., van Koll, J., Ghossein, M., Mourmans, S. G. J., Aizpurua, A. B., van Stipdonk, A. M. W., Vernooy, K., Prinzen, F. W., Rocca, H.-P. B.-L., Knackstedt, C., & van Empel, V. P. M. (2025). Prevalence and prognostic value of ventricular conduction delay in heart failure with preserved ejection fraction. IJC Heart and Vasculature, 57, Article 101622. https://doi.org/10.1016/j.ijcha.2025.101622
- Gunawardene, M. A., Puererfellner, H., Merino, J. L., Linz, D., Sultan, A., Scherr, D., Deharo, J. C., Wohlmuth, P., Feldhege, J., Costa, F. M., Ribeiro, S., Charitakis, E., Verstrael, A., Anselmino, M., Szeplaki, G., Simovic, S., Jadczyk, T., Adelino, R., Katsoularis, I., ... Chun, K.-R. J. (2025). PULSE survey: Population Survey on Knowledge, Gaps and Perception of Heart Rhythm disorders-an initiative of the Scientific Initiatives Committee of the European Heart Rhythm Association. EP Europace, 27(4), Article euaf032. https://doi.org/10.1093/europace/euaf032
- Kirchhof, P., Andrade, J. G., Vernooy, K., Metzner, A., & Nies, M. (2025). Top Stories: Ablation in atrial fibrillation. Heart Rhythm, 22(4), 1121-1122. https://doi.org/10.1016/j.hrthm.2024.12.029
- Sohns, C., Fink, T., Crijns, H. J. G. M., Costard-Jaeckle, A., Marrouche, N. F., Sossalla, S., Schramm, R., El Hamriti, M., Moersdorf, M., Didenko, M., Braun, M., Sciacca, V., Konietschke, F., Rudolph, V., Gummert, J., Tijssen, J. G. P., Sommer, P., & CASTLE-VTInvestigators (2025). Preventive catheter ablation for ventricular arrhythmias in patients with end-stage heart failure referred for heart transplantation evaluation: Rationale for and design of the CASTLE-VT trial. European journal of heart failure, 27(4), 690-696. https://doi.org/10.1002/ejhf.3512
- Lumens, J. (2025). The Double Dyssynchrony Paradox: When Cardiac Discord Signals Hope. JACC-Cardiovascular Imaging, 18(4), 433-435. https://doi.org/10.1016/j.jcmg.2025.01.003
- van Nuland, P. J. A., Halim, J., van Ginkel, D. J., Overduin, D. C., Brouwer, J., Nijenhuis, V. J., van't Hof, A. W. J., Tonino, P. A. L., ten Berg, J. M., & Vriesendorp, P. A. (2025). The Impact of Permanent Pacemaker Implantation After TAVI on Mortality and Quality of Life: A POPular TAVI Substudy. Catheterization and Cardiovascular interventions, 105(5), 1098-1107. https://doi.org/10.1002/ccd.31431
- Schotten, U., Goette, A., & Verheule, S. (2025). Translation of pathophysiological mechanisms of atrial fibrosis into new diagnostic and therapeutic approaches. Nature Reviews Cardiology, 22(4), 225-240. https://doi.org/10.1038/s41569-024-01088-w
- Rikken, S. A. O. F., Gibson, C. M., Bahit, M. C., Duffy, D., Chi, G., Korjian, S., Mohammadnia, N., White, H., Anschuetz, G., Kingwell, B. A., Ophuis, T. O., Nicolau, J. C., Lopes, R. D., Lewis, B. S., El Messaoudi, S., Vinereanu, D., Ten Berg, J. M., Goodman, S. G., Bode, C., ... AEGIS-II Committees and Investigators (2025). Impact of Apolipoprotein A-I Infusions on Cardiovascular Events Post-MI by Neutrophil-Lymphocyte Ratio and LDL-Cholesterol Levels. JACC: Advances, 4(5), Article 101727. https://doi.org/10.1016/j.jacadv.2025.101727
- Kirchhof, P., Camm, A. J., Crijns, H. J. G. M., Piccini, J. P., Torp-Pedersen, C., McKindley, D. S., Wieloch, M., & Hohnloser, S. H. (2025). Dronedarone provides effective early rhythm control: post-hoc analysis of the ATHENA trial using EAST-AFNET 4 criteria. EP Europace, 27(4), Article euaf080 . https://doi.org/10.1093/europace/euaf080
- Sohns, C., Marrouche, N. F., Crijns, H. J. G. M., Sossalla, S., Sciacca, V., Tijssen, J. G. P., Sommer, P., & CASTLE HTx Investigators (2025). In Castle-Htx Trial We Trust. Journal of the American College of Cardiology, 85(11), 1207-1209. https://doi.org/10.1016/j.jacc.2024.10.092
- Wang, T., Karel, J., Osnabrugge, N., Driessens, K., Stoks, J., Cluitmans, M., Volders, P., Bonizzi, P., & Peeters, R. (2025). Deep learning based estimation of heart surface potentials. Artificial Intelligence in Medicine, 163, Article 103093. https://doi.org/10.1016/j.artmed.2025.103093
- El Bounkari, O., Zan, C., Yang, B., Ebert, S., Wagner, J., Bugar, E., Kramer, N., Bourilhon, P., Kontos, C., Zarwel, M., Sinitski, D., Milic, J., Jansen, Y., Kempf, W. E., Sachs, N., Maegdefessel, L., Ji, H., Gokce, O., Riols, F., ... Bernhagen, J. (2025). An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis. Nature Communications, 16(1), Article 2297. https://doi.org/10.1038/s41467-025-57540-z
- Smits, K. C., Bressi, E., Rademakers, L. M., Rijks, J. H. J., van Stipdonk, A. M. W., Engels, E. B., Isaacs, A., Hermans, B. J. M., Grieco, D., Luermans, J. G. L. M., Vernooy, K., Prinzen, F. W., & Nguyen, U. C. (2025). Time-dependent repolarization changes following left bundle branch area pacing vs. conventional biventricular pacing in patients with dyssynchronous heart failure. EP Europace, 27(3), Article euaf034. https://doi.org/10.1093/europace/euaf034
- Roselli, C., Surakka, I., Olesen, M. S., Sveinbjornsson, G., Marston, N. A., Choi, S. H., Holm, H., Chaffin, M., Gudbjartsson, D., Hill, M. C., Aegisdottir, H., Albert, C. M., Alonso, A., Anderson, C. D., Arking, D. E., Arnar, D. O., Barnard, J., Benjamin, E. J., Braunwald, E., ... Ellinor, P. T. (2025). Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases. Nature Genetics, 57(3), 539-547. Article 11303. https://doi.org/10.1038/s41588-024-02072-3
- van Deutekom, C., van de Lande, M. E., Rama, R., Nguyen, B.-O., Tieleman, R. G., Weberndoerfer, V., Hemels, M. E. W., de Melis, M., Schotten, U., Linz, D., Crijns, H. J. G. M., van Gelder, I. C., & Rienstra, M. (2025). Multimorbidity Is Associated With Symptom Severity and Disease Progression in Patients with Paroxysmal Atrial Fibrillation-Data From the RACE V Study. Journal of the American Heart Association, 14(5), Article e034514. https://doi.org/10.1161/JAHA.123.034514
- Scheenstra, B., van Susante, L., Bongers, B. C., Lenssen, T., Knols, H., van Kuijk, S., Nieman, M., Maessen, J., Van't Hof, A., Sardari Nia, P., & Digital Cardiac Counseling (DCC) Trial investigators (2025). The Effect of Teleprehabilitation on Adverse Events After Elective Cardiac Surgery: A Randomized Controlled Trial. Journal of the American College of Cardiology, 85(8), 788-800. https://doi.org/10.1016/j.jacc.2024.10.064
- van Mourik, M. J. W., Keijsers, L., van der Velden, R. M. J., Vorstermans, B., Crijns, H. J. G. M., Muris, J. W. M., Linz, D. K., & Gidding-Slok, A. (2025). Patients perspectives on integrating eHealth in regular care pathways for atrial fibrillation: evaluating photoplethysmography for remote self-assessment. European Journal of Cardiovascular Nursing, 24(2), 305-313. https://doi.org/10.1093/eurjcn/zvae156
- Mills, G. B., Kotanidis, C. P., Mehta, S., Tiong, D., Badings, E. A., Engstrøm, T., van 't Hof, A. W. J., Høfsten, D., Holmvang, L., Jobs, A., Køber, L., Milasinovic, D., Milosevic, A., Stankovic, G., Thiele, H., Mehran, R., & Kunadian, V. (2025). Early Versus Delayed Invasive Management of Female Patients With Non-ST-Elevation Acute Coronary Syndrome: An Individual Patient Data Meta-Analysis. Circulation-Cardiovascular Interventions, 18(3), e014763. Article 014763. https://doi.org/10.1161/CIRCINTERVENTIONS.124.014763
- Lemmens, M.-J. D. K., Heuts, S., Bidar, E., Wildberger, J. E., Mihl, C., & Smulders, M. W. (2025). Integrating Coronary Artery Assessment and Myocardial Late Enhancement Imaging With Photon-Counting Detector CT: Visualizing the Invisible. Circulation-Cardiovascular Imaging, 18(3), e017238. Article e017238. https://doi.org/10.1161/CIRCIMAGING.124.017238
- Isaksen, J. L., Arildsen, B., Lind, C., Nørregaard, M., Vernooy, K., Schotten, U., Jespersen, T., Betz, K., Hermans, A. N. L., Kanters, J. K., & Linz, D. (2025). Raw photoplethysmogram waveforms versus peak-to-peak intervals for machine learning detection of atrial fibrillation: Does waveform matter?Computer Methods and Programs in Biomedicine, 260, Article 108537. https://doi.org/10.1016/j.cmpb.2024.108537
- Beela, A. S., Manetti, C. A., Prinzen, F. W., Delhaas, T., Herbots, L., & Lumens, J. (2025). The mechanistic interaction between mechanical dyssynchrony and filling pressure in cardiac resynchronization therapy candidates. European Heart Journal Cardiovascular Imaging, 26(3), 424-434. Article jeae286. https://doi.org/10.1093/ehjci/jeae286
- Johnson, L. S., Zadrozniak, P., Jasina, G., Grotek-Cuprjak, A., Andrade, J. G., Svennberg, E., Diederichsen, S. Z., McIntyre, W. F., Stavrakis, S., Benezet-Mazuecos, J., Krisai, P., Iakobishvili, Z., Laish-Farkash, A., Bhavnani, S., Ljungström, E., Bacevicius, J., van Vreeswijk, N. L., Rienstra, M., Spittler, R., ... Et al. (2025). Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography. Nature Medicine, 31(3), 925-931. Article e13090. https://doi.org/10.1038/s41591-025-03516-x
- Woelders, E. C. I., Peeters, D. A. M., Janssen, S., Luijkx, J. J. P., Winkler, P. J. C., Damman, P., Remkes, W. S., van't Hof, A. W. J., van Geuns, R. J. M., & ZON HR investigators (2025). Design and rationale of the South-East Netherlands Heart Registry (ZON-HR). Netherlands Heart Journal, 33(3), 76-84. https://doi.org/10.1007/s12471-025-01934-7
- Gilbers, M. D., Kawczynski, M. J., Bidar, E., Maesen, B., Isaacs, A., Winters, J., Linz, D., Rienstra, M., van Gelder, I., Maessen, J. G., & Schotten, U. (2025). Determinants and impact of postoperative atrial fibrillation burden during 2.5 years of continuous rhythm monitoring after cardiac surgery: Results from the RACE V prospective cohort study. Heart Rhythm, 22(3), 647-660. https://doi.org/10.1016/j.hrthm.2024.08.014
- Shahrbabaki, S. S., Dharmaprani, D., Tiver, K. D., Jenkins, E., Strong, C., Tonchev, I., O'Loughlin, L. P., Linz, D., Chapman, D., Lechat, B., Ullah, S., Stone, K. L., Eckert, D. J., Baumert, M., & Ganesan, A. N. (2025). Power-law properties of nocturnal arrhythmia avalanches: a novel marker for incident cardiovascular events. Heart Rhythm, 22(3), 796-805. https://doi.org/10.1016/j.hrthm.2024.08.015
- Parma, L., Sachs, N., Sobczak, N., Li, Z., Merchant, K., Pauli, J., Depuydt, M. A. C., Wezel, A., Smeets, H. J., Bot, I., Sluetter, B., Maegdefessel, L., Weber, C., Duchene, J., & Megens, R. T. A. (2025). CXCL12 Derived From ACKR1<SUP>+</SUP> Intraplaque Neovessels Mediates CD8<SUP>+</SUP> T Cell Recruitment in Human Atherosclerosis. Circulation, 151(8), 581-584. https://doi.org/10.1161/CIRCULATIONAHA.124.072560
- de Riva, M., Evertz, R., Lukac, P., Dekker, L. R. C., Blaauw, Y., ter Bekke, R. M. A., Kimura, Y., Beukema, R. J., Ouss, A., Mulder, B. A., Vernooy, K., Wijnmaalen, A. P., & Zeppenfeld, K. (2025). Evoked delayed potential ablation for post-myocardial infarction ventricular tachycardia: results from a large prospective multicentre study. EP Europace, 27(2), Article euaf003. https://doi.org/10.1093/europace/euaf003
- Ganesan, P., Pedron, M., Feng, R., Rogers, A. J., Deb, B., Chang, H. J., Ruiperez-Campillo, S., Srivastava, V., Brennan, K. A., Giles, W., Baykaner, T., Clopton, P., Wang, P. J., Schotten, U., Krummen, D. E., & Narayan, S. M. (2025). Comparing Phenotypes for Acute and Long-Term Response to Atrial Fibrillation Ablation Using Machine Learning. Circulation-Arrhythmia and Electrophysiology, 18(2), Article e012860. https://doi.org/10.1161/CIRCEP.124.012860
- Maass, A. H., Tuinenburg, A., Mairuhu, G., Faes, M. C., Klinkenberg, T. J., Ruigrok, S., Koster, M., Stegeman, B. H., & Luermans, J. G. L. M. (2025). 2021 European Society of Cardiology guidelines on cardiac pacing and cardiac resynchronisation therapy: Statement of endorsement by the NVVC. Netherlands Heart Journal, 33(2), 38-45. https://doi.org/10.1007/s12471-024-01927-y
- Manninger, M., Zweiker, D., Hovakimyan, T., Matusik, P. T., Conti, S., Ollitrault, P., Aro, A., Mulder, B. A., Dichtl, W., Heeger, C. H., ter Bekke, R. M. A., Gul, E. E., Weijs, B., Rahm, A. K., Darma, A., Evranos, B., Sabbag, A., Moroka, K., Traykov, V., ... Linz, D. (2025). Author's Reply to “Digital Devices for Arrhythmia Detection: What Is Still Missing?”. Clinical Cardiology, 48(2), Article e70092. https://doi.org/10.1002/clc.70092
- Isaacs, A., Zeemering, S., Winters, J., Batlle, M., Bidar, E., Boukens, B., Casadei, B., Chua, W., Crijns, H. J. G. M., Fabritz, L., Guasch, E., Hatem, S. N., Hermans, B., Kääb, S., Kawczynski, M., Maesen, B., Maessen, J., Mont, L., Sinner, M. F., ... Stoll, M. (2025). Lateral Atrial Expression Patterns Provide Insights into Local Transcription Disequilibrium Contributing to Disease Susceptibility. Circulation: Genomic and Precision Medicine, 18(1), Article e004594. https://doi.org/10.1161/CIRCGEN.124.004594
- Boukens, B. J., & Porta-Sanchez, A. (2025). Repolarization Mapping in Brugada Syndrome Patients. JACC: Clinical Electrophysiology, 11(2), 418-419. https://doi.org/10.1016/j.jacep.2024.10.036
- Arslan, M., Schaap, J., van Gorsel, B., Aubanell, A., Budde, R. P. J., Hirsch, A., Smulders, M. W., Mihl, C., Damman, P., Sliwicka, O., Habets, J., Dubois, E. A., & Dedic, A. (2025). Coronary computed tomography angiography improves assessment of patients with acute chest pain and inconclusively elevated high-sensitivity troponins. European Radiology, 35(2), 789-797. https://doi.org/10.1007/s00330-024-10930-1
- Munneke, A. G., Lumens, J., & Delhaas, T. (2025). Diagnostic value of reversed differential cyanosis in (supra)cardiac total anomalous pulmonary venous return. Pediatric Research, 97(2), 809-817. Article 113366. https://doi.org/10.1038/s41390-024-03355-5
- Sciacca, V., Sohns, C., Crijns, H. J. G. M., Marrouche, N. F., Schramm, R., Moersdorf, M., Fink, T., Bergau, L., Hindricks, G., Dagres, N., Sossalla, S., Costard-Jaeckle, A., Fox, H., El Hamriti, M., Konietschke, F., Rudolph, V., Gummert, J., Tijssen, J. G. P., Sommer, P., & CASTLE HTx Investigators (2025). Effects of atrial fibrillation ablation on arrhythmia burden and ventricular function in end-stage heart failure: Lessons from CASTLE-HTx. European journal of heart failure, 27(2), 255-263. https://doi.org/10.1002/ejhf.3505
- Mourmans, S. G. J., Weerts, J., Baumert, M., Aizpurua, A. B., Achten, A., Knackstedt, C., Linz, D., & van Empel, V. P. M. (2025). Prognostic value of hypoxaemic burden from overnight oximetry in heart failure with preserved ejection fraction. Esc heart failure, 12(1), 622-630. https://doi.org/10.1002/ehf2.15116
- Woelders, E. C. I., Onuma, Y., Ninomiya, K., O'Leary, N., Damman, P., Peeters, D. A. M., Hof, A. W. J. V. ., Valgimigli, M., Vranckx, P., Windecker, S., Serruys, P. W. J. C., & van Geuns, R.-J. M. (2025). Parsimonious versus extensive bleeding score: can we simplify risk stratification after percutaneous coronary intervention and reduce bleeding events by de-escalation of the antiplatelet strategy?Open Heart, 12(1), Article e003083. https://doi.org/10.1136/openhrt-2024-003083
- Plesinger, F., Hassouna, S., Carna, Z., Vesela, J., Smisek, R., Vargova, E., Sobota, V., Koscova, Z., Nejedly, P., Viscor, I., Prinzen, F. W., Jurak, P., Halamek, J., & Osmancik, P. (2025). Automatically optimized vectorcardiographic features are associated with recurrence of atrial fibrillation after electrical cardioversion. Scientific Reports, 15(1), Article 1257. https://doi.org/10.1038/s41598-025-85340-4



