Roberto Lorusso

Professor

Prof. Roberto Lorusso studied medicine at the University of Milan, Italy and graduated in 1987 magna cum Laude. He worked at Maastricht UMC+ in 1990 at CTC research and in 1996 and 1997 at the academic Hospital of Leuven. In 1998, he successfully obtained his PhD degree at Maastricht University (thesis titled 'Cardiac reinforcement and assistance by electrically stimulated skeletal muscle').

Currently, Prof. Roberto Lorusso is staff member at the Department of Cardiothoracic Surgery at Maastricht UMC+, Director of the Extracorporeal Life Support (ECLS) Program, Full Professor of Cardiac Surgery and ECLS at the Maastricht University and CARIM. His research group is focussed on mechanical circulatory support, minimally invasive valve surgery, coronary surgery, cardiac valve disease, extracorporeal circulation, acute myocardial infarction complications, cardiac valve disease, preclinical and clinical research.

Prof. Roberto Lorusso won the Gasperis-Donatelli Prize in 1989, a Young Investigator Award in 1995 and the Lillehei Award in 1998 by the European Association for Cardio-Thoracic Surgery. He was Scientific Secretary of the Italian Society for Cardiac Surgery in 2007 and 2008, President of Euro-ELSO (2015-2017), and he is currently Editor-in-Chief of the Multi-Media Manual of Cardio-Thoracic Surgery as well as member of the ELSO Executive Committee.

He has almost 300 publications in PubMed, and has given more than 300 presentations at international meetings as invited speaker. He is Principal Investigator of international multicentre clinical studies and grant receiver from several funding bodies for clinical as well as pre-clinical investigations.

Department of Cardiothoracic surgery
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
Room number: D.2037
T: +31(0)43 387 60 32

2021
- Makhoul, M., Heuts, S., Mansouri, A., Taccone, F. S., Obeid, A., Mirko, B., Broman, L. M., Malfertheiner, M. V., Meani, P., Raffa, G. M., Delnoij, T., Maessen, J., Bolotin, G., & Lorusso, R. (2021). Understanding the "extracorporeal membrane oxygenation gap" in veno-arterial configuration for adult patients: Timing and causes of death. Artificial Organs, 45(10), 1155-1167. https://doi.org/10.1111/aor.14006
- Bonalumi, G., Giambuzzi, I., Lorusso, R., & Di Mauro, M. (2021). Whatever happens, two mammary is better than one. Journal of Cardiac Surgery, 36(10), 3639-3640. https://doi.org/10.1111/jocs.15800
- Ronco, D., Matteucci, M., & Lorusso, R. (2021). REPLY: Temporary Mechanical Circulatory Support in Postinfarct Ventricular Septal Defect Time for an Upgrade?Jacc-Cardiovascular Interventions, 14(17), 1955-1956. https://doi.org/10.1016/j.jcin.2021.07.027
- Nasso, G., Lorusso, R., Motekallemi, A., Dell'Aquila, A. M., Di Bari, N., Condello, I., Moscarelli, M., Iacopino, S., Serraino, G. F., Mastroroberto, P., Santarpino, G., & Speziale, G. (2021). The fate of patients after failed epicardial ablation of atrial fibrillation. Journal of Cardiothoracic Surgery, 16(1), Article 249. https://doi.org/10.1186/s13019-021-01635-3
- Matteucci, M., Formica, F., Kowalewski, M., Massimi, G., Ronco, D., Beghi, C., & Lorusso, R. (2021). Meta-analysis of surgical treatment for postinfarction left ventricular free-wall rupture. Journal of Cardiac Surgery, 36(9), 3326-3333. https://doi.org/10.1111/jocs.15701
- Mariani, S., Napp, L. C., Kraaier, K., Li, T., Bounader, K., Hanke, J. S., Dogan, G., Schmitto, J. D., & Lorusso, R. (2021). Prophylactic mechanical circulatory support for protected ventricular tachycardia ablation: A meta-analysis of the literature. Artificial Organs, 45(9), 987-997. https://doi.org/10.1111/aor.13945
- Sala, A., Lorusso, R., Bargagna, M., Ruggeri, S., Buzzatti, N., Scandroglio, M., Monaco, F., Agricola, E., Giacomini, A., Carino, D., Meneghin, R., Schiavi, D., Lapenna, E., Denti, P., Blasio, A., Alfieri, O., Castiglioni, A., & De Bonis, M. (2021). Complicated postoperative course in isolated tricuspid valve surgery: Looking for predictors. Journal of Cardiac Surgery, 36(9), 3092-3099. https://doi.org/10.1111/jocs.15739
- Heuts, S., Ubben, J. F., Banks-Gonzales, V., Sels, J.-W., Lorusso, R., van Mook, W. N. K. A., & Delnoij, T. S. R. (2021). Nitric Oxide Ventilation Improves Recirculation and Right Ventricular Function During Veno-Venous Extracorporeal Membrane Oxygenation in a COVID-19 Patient. Journal of Cardiothoracic and Vascular Anesthesia, 35(9), 2763-2767. https://doi.org/10.1053/j.jvca.2020.09.137
- Lorusso, R., & Mueller, T. (2021). COVID-19 and ECMO: a call for close cooperation and more investigation. The Lancet Respiratory medicine, 9(8), 805-807. https://doi.org/10.1016/s2213-2600(21)00128-4
- Broman, L. M., Eksborg, S., Lo Coco, V., Piero, M. E., Belohlavek, J., Lorusso, R., & EuroECMO COVID-19 Working Group (2021). Extracorporeal membrane oxygenation for COVID-19 during first and second waves. The Lancet Respiratory medicine, 9(8), E80-E81. https://doi.org/10.1016/s2213-2600(21)00262-9
- Willers, A., Arens, J., Mariani, S., Pels, H., Maessen, J. G., Hackeng, T. M., Lorusso, R., & Swol, J. (2021). New Trends, Advantages and Disadvantages in Anticoagulation and Coating Methods Used in Extracorporeal Life Support Devices. Membranes, 11(8), Article 617. https://doi.org/10.3390/membranes11080617
- Kaddoura, R., Omar, A. S., Ibrahim, M. I. M., Alkhulaifi, A., Lorusso, R., Elsherbini, H., Soliman, O., & Caliskan, K. (2021). The Effectiveness of Levosimendan on Veno-Arterial Extracorporeal Membrane Oxygenation Management and Outcome: A Systematic Review and Meta-Analysis. Journal of Cardiothoracic and Vascular Anesthesia, 35(8), 2483-2495. https://doi.org/10.1053/j.jvca.2021.01.019
- Chiarini, G., Cho, S.-M., Whitman, G., Rasulo, F., & Lorusso, R. (2021). Brain Injury in Extracorporeal Membrane Oxygenation: A Multidisciplinary Approach. Seminars in Neurology, 41(04), 422-436. https://doi.org/10.1055/s-0041-1726284
- Lorusso, R., Shekar, K., MacLaren, G., Schmidt, M., Pellegrino, V., Meyns, B., Haft, J., Vercaemst, L., Pappalardo, F., Bermudez, C., Belohlavek, J., Hou, X., Boeken, U., Castillo, R., Donker, D. W., Abrams, D., Ranucci, M., Hryniewicz, K., Chavez, I., ... Combes, A. (2021). ELSO Interim Guidelines for Venoarterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients. Asaio Journal, 67(8), 827-844. https://doi.org/10.1097/MAT.0000000000001510
- Mariani, S., Li, T., Boethig, D., Napp, L. C., Chatterjee, A., Homann, K., Bounader, K., Hanke, J. S., Dogan, G., Lorusso, R., Bauersachs, J., Haverich, A., & Schmitto, J. D. (2021). Lateral Thoracotomy for Ventricular Assist Device Implantation: A Meta-Analysis of Literature. Asaio Journal, 67(8), 845-855. https://doi.org/10.1097/MAT.0000000000001359
- Kurniawati, E. R., Rutjens, V. G. H., Vranken, N. P. A., Delnoij, T. S. R., Lorusso, R., van der Horst, I. C. C., Maessen, J. G., & Weerwind, P. W. (2021). Quality of life following adult veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review. Quality of Life Research, 30(8), 2123-2135. https://doi.org/10.1007/s11136-021-02834-0
- van der Boon, R. M. A., den Dekker, W. K., Meuwese, C. L., Lorusso, R., von der Thusen, J. H., Constantinescu, A. C., Manintveld, O. C., Delnoij, T. S. R., van der Heijden, J. J., van Mieghem, N. M. D. A., & den Uil, C. A. (2021). Safety of Endomyocardial Biopsy in New-Onset Acute Heart Failure Requiring Veno-Arterial Extracorporeal Membrane Oxygenation. Circulation-Heart Failure, 14(8), Article 008387. https://doi.org/10.1161/circheartfailure.121.008387
- Matteucci, M., Ronco, D., Corazzari, C., Fina, D., Jiritano, F., Meani, P., Kowalewski, M., Beghi, C., & Lorusso, R. (2021). Surgical Repair of Postinfarction Ventricular Septal Rupture: Systematic Review and Meta-Analysis. Annals of Thoracic Surgery, 112(1), 326-337. https://doi.org/10.1016/j.athoracsur.2020.08.050
- Lorusso, R., Lo Coco, V., & Mariani, S. (2021). Left ventricular assist device and right ventricular dysfunction: how to predict and manage a potentially perilous path?European Journal of Cardio-Thoracic Surgery, 60(1), 186-188. https://doi.org/10.1093/ejcts/ezab154
- Kowalewski, M., Zielinski, K., Brodie, D., MacLaren, G., Whitman, G., Raffa, G. M., Boeken, U., Shekar, K., Chen, Y.-S., Bermudez, C., D'Alessandro, D., Hou, X., Haft, J., Belohlavek, J., Dziembowska, I., Suwalski, P., Alexander, P., Barbaro, R. P., Gaudino, M., ... Lorusso, R. (2021). Venoarterial Extracorporeal Membrane Oxygenation for Postcardiotomy Shock-Analysis of the Extracorporeal Life Support Organization Registry*. Critical Care Medicine, 49(7), 1107-1117. https://doi.org/10.1097/CCM.0000000000004922
- Nasso, G., Lorusso, R., Moscarelli, M., De Martino, G., Dell'Aquila, A. M., Motekallemi, A., Di Bari, N., Condello, I., Mastroroberto, P., Santarpino, G., & Speziale, G. (2021). Catheter, surgical, or hybrid procedure: what future for atrial fibrillation ablation?Journal of Cardiothoracic Surgery, 16(1), Article 186. https://doi.org/10.1186/s13019-021-01565-0
- Li Bassi, G., Suen, J. Y., Dalton, H. J., White, N., Shrapnel, S., Fanning, J. P., Liquet, B., Hinton, S., Vuorinen, A., Booth, G., Millar, J. E., Forsyth, S., Panigada, M., Laffey, J., Brodie, D., Fan, E., Torres, A., Chiumello, D., Corley, A., ... Lorusso, R. (2021). An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients. Critical Care, 25(1), Article 199. https://doi.org/10.1186/s13054-021-03518-4
- Di Nardo, M., Lorusso, R., Guner, Y., Schomberg, J., & De Luca, D. (2021). Feasibility of Lung Ultrasound to Monitor Aeration in Children Supported With Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome. Asaio Journal, 67(6), E104-E106. https://doi.org/10.1097/MAT.0000000000001264
- Suwalski, P., Staromlynski, J., Braczkowski, J., Bartczak, M., Mariani, S., Drobinski, D., Szuldrzynski, K., Smoczynski, R., Franczyk, M., Sarnowski, W., Gajewska, A., Witkowska, A., Wierzba, W., Zaczynski, A., Krol, Z., Olek, E., Pasierski, M., Ravaux, J. M., de Piero, M. E., ... Kowalewski, M. (2021). Transition from Simple V-V to V-A and Hybrid ECMO Configurations in COVID-19 ARDS. Membranes, 11(6), Article 434. https://doi.org/10.3390/membranes11060434
- Belliato, M., Cremascoli, L., Epis, F., Ferrari, F., Quattrone, M. G., Malfertheiner, M., Broman, L. M., Aliberti, A., Taccone, F. S., Iotti, G. A., & Lorusso, R. (2021). Carbon Dioxide Elimination During Veno-Venous Extracorporeal Membrane Oxygenation Weaning: A Pilot Study. Asaio Journal, 67(6), 700-708. https://doi.org/10.1097/MAT.0000000000001282
- Mueller, T., Brodie, D., Lorusso, R., MacLaren, G., & Ichiba, S. (2021). Expanding controlled donation after the circulatory determination of death: stronger emphasis on different cultural, religious and legal backgrounds is needed. Intensive Care Medicine, 47(6), 724-725. https://doi.org/10.1007/s00134-021-06405-2
- Lorusso, R. (2021). First Myocardial Resting or First Myocardial Revascularization for Cardiogenic Shock After Acute Myocardial Infarction-Related Cardiac Arrest? Still a Hamlet Dilemma ...Now, With Some More Clues ...Critical Care Medicine, 49(6), 999-1000. https://doi.org/10.1097/CCM.0000000000004932
- Ravaux, J. M., Di Mauro, M., Vernooy, K., Mariani, S., Ronco, D., Simons, J., Van't Hof, A. W., Veenstra, L., Kats, S., Maessen, J. G., & Lorusso, R. (2021). Impact of Bundle Branch Block on Permanent Pacemaker Implantation after Transcatheter Aortic Valve Implantation: A Meta-Analysis. Journal of Clinical Medicine, 10(12), Article 2719. https://doi.org/10.3390/jcm10122719
- Martucci, G., Amata, M., di Francesco, F., Traina, M., Arcadipane, A., Lorusso, R., & Granata, A. (2021). Management of intra-abdominal hypertension during ECMO: Total water-assisted colonoscopy as a step-up minimally invasive treatment, and a literature review. Endoscopy international open, 09(06), E848-E852. https://doi.org/10.1055/a-1399-8209
- Ravaux, J., Di Mauro, M., Vernooy, K., van 't Hof, A., Veenstra, L., Kats, S., Maessen, J., & Lorusso, R. (2021). One-year pacing dependency after pacemaker implantation in patients undergoing transcatheter aortic valve implantation: Systematic review and meta-analysis. Journal of Thoracic and Cardiovascular Surgery, 6, 41-55.e15. https://doi.org/10.1016/j.xjon.2021.02.002
- Di Mauro, M., Lorusso, R., Parolari, A., Ravaux, J. M., Bonalumi, G., Guarracini, S., Ricci, F., Benedetto, U., & Calafiore, A. M. (2021). The best approach for functional tricuspid regurgitation: A network meta-analysis. Journal of Cardiac Surgery, 36(6), 2072-2080. https://doi.org/10.1111/jocs.15378
- Moscarelli, M., Lorusso, R., Abdullahi, Y., Varone, E., Marotta, M., Solinas, M., Casula, R., Parlanti, A., Speziale, G., Fattouch, K., & Athanasiou, T. (2021). The Effect of Minimally Invasive Surgery and Sternotomy on Physical Activity and Quality of Life. Heart Lung and Circulation, 30(6), 882-887. https://doi.org/10.1016/j.hlc.2020.09.936
- Ronco, D., Matteucci, M., Ravaux, J. M., Marra, S., Torchio, F., Corazzari, C., Massimi, G., Beghi, C., Maessen, J., & Lorusso, R. (2021). Mechanical Circulatory Support as a Bridge to Definitive Treatment in Post-Infarction Ventricular Septal Rupture. Jacc-Cardiovascular Interventions, 14(10), 1053-1066. https://doi.org/10.1016/j.jcin.2021.02.046
- Mang, S., Kalenka, A., Broman, L. M., Supady, A., Swol, J., Danziger, G., Becker, A., Horsch, S. I., Mertke, T., Kaiser, R., Bracht, H., Zotzmann, V., Seiler, F., Bals, R., Taccone, F. S., Moerer, O., Lorusso, R., Belohlavek, J., Muellenbach, R. M., ... COVEC-Study Group (2021). Extracorporeal life support in COVID-19-related acute respiratory distress syndrome: A EuroELSO international survey. Artificial Organs, 45(5), 495-505. https://doi.org/10.1111/aor.13940
- Matteucci, M., Ferrarese, S., Corazzari, C., Telli, G., Mantovani, V., Lorusso, R., & Beghi, C. (2021). Ascending aortic aneurysm repair in the setting of Tako-tsubo cardiomyopathy. Perfusion, 36(4), 429-431. Article 0267659120950206. https://doi.org/10.1177/0267659120950206
- Willers, A., Swol, J., Kowalewski, M., Raffa, G. M., Meani, P., Jiritano, F., Matteucci, M., Fina, D., Heuts, S., Bidar, E., Natour, E., Sels, J. W., Delnoij, T., & Lorusso, R. (2021). Extracorporeal Life Support in Hemorrhagic Conditions: A Systematic Review. Asaio Journal, 67(5), 476-484. https://doi.org/10.1097/mat.0000000000001216
- Badulak, J., Antonini, M. V., Stead, C. M., Shekerdemian, L., Raman, L., Paden, M. L., Agerstrand, C., Bartlett, R. H., Barrett, N., Combes, A., Lorusso, R., Mueller, T., Ogino, M. T., Peek, G., Pellegrino, V., Rabie, A. A., Salazar, L., Schmidt, M., Shekar, K., ... ELSO COVID-19 Working Group Members (2021). Extracorporeal Membrane Oxygenation for COVID-19: Updated 2021 Guidelines from the Extracorporeal Life Support Organization. Asaio Journal, 67(5), 485-495. https://doi.org/10.1097/MAT.0000000000001422
- Czerny, M., van den Berg, J., Chiesa, R., Jacobs, M., Jakob, S., Jenni, H. J., Lorusso, R., Pacini, D., Quintana, E., Rylski, B., Staier, K., Tsilimparis, N., Wyss, T., Gottardi, R., & Schmidli, J. (2021). Management of acute and chronic aortic disease during the COVID-19 pandemic-Results from a web-based ad hoc platform. Journal of Cardiac Surgery, 36(5), 1683-1692. https://doi.org/10.1111/jocs.15093
- Ravaux, J. M., Di Mauro, M., Vernooy, K., Van't Hof, A. W., Veenstra, L., Kats, S., Maessen, J. G., & Lorusso, R. (2021). Do Women Require Less Permanent Pacemaker After Transcatheter Aortic Valve Implantation? A Meta-Analysis and Meta-Regression. Journal of the American Heart Association, 10(7), Article 019429. https://doi.org/10.1161/JAHA.120.019429
- Makhoul, M., Lorusso, R., Bidar, E., Zayad, R., & Natour, E. (2021). Misdiagnosed Recurrent Pericardial Effusion in Chronic Type A Aortic Dissection. Israel Medical Association Journal, 23(4), 258-260. https://pubmed.ncbi.nlm.nih.gov/33899362/
- Lorusso, R., Whitman, G., Milojevic, M., Raffa, G., McMullan, D. M., Boeken, U., Haft, J., Bermudez, C., Shah, A., & D'Alessandro, D. A. (2021). 2020 EACTS/ELSO/STS/AATS expert consensus on post-cardiotomy extracorporeal life support in adult patients. Journal of Thoracic and Cardiovascular Surgery, 161(4), 1287-1331. https://doi.org/10.1016/j.jtcvs.2020.09.045
- Supady, A., Curtis, J. R., Abrams, D., Lorusso, R., Bein, T., Boldt, J., Brown, C. E., Duerschmied, D., Metaxa, V., & Brodie, D. (2021). Allocating scarce intensive care resources during the COVID-19 pandemic: practical challenges to theoretical frameworks. The Lancet Respiratory medicine, 9(4), 430-434. https://doi.org/10.1016/s2213-2600(20)30580-4
- Lo Coco, V., Swol, J., De Piero, M. E., Massimi, G., Chiarini, G., Broman, L. M., & Lorusso, R. (2021). Dynamic extracorporeal life support: A novel management modality in temporary cardio-circulatory assistance. Artificial Organs, 45(4), 427-434. https://doi.org/10.1111/aor.13869
- Kowalewski, M., Zielinski, K., Gozdek, M., Raffa, G. M., Pilato, M., Alanazi, M., Gilbers, M., Heuts, S., Natour, E., Bidar, E., Schreurs, R., Delnoij, T., Driessen, R., Sels, J. W., van de Poll, M., Roekaerts, P., Pasierski, M., Meani, P., Maessen, J., ... Lorusso, R. (2021). Veno-Arterial Extracorporeal Life Support in Heart Transplant and Ventricle Assist Device Centres. Meta-analysis. Esc heart failure, 8(2), 1064-1075. https://doi.org/10.1002/ehf2.13080
- Lorusso, R., Belliato, M., Mazzeffi, M., Di Mauro, M., Taccone, F. S., Parise, O., Albanawi, A., Nandwani, V., McCarthy, P., Kon, Z., Menaker, J., Johnson, D. M., Gelsomino, S., & Herr, D. (2021). Neurological complications during veno-venous extracorporeal membrane oxygenation: Does the configuration matter? A retrospective analysis of the ELSO database. Critical Care, 25(1), Article 107. https://doi.org/10.1186/s13054-021-03533-5
- Holvoet, W., van Soest, K., Havenith, T., Lorusso, R., van Mook, W. N. K. A., & Delnoij, T. (2021). Bail-out extracorporeal membrane oxygenation for hydroxychloroquine intoxication: a warning for COVID-19 health-care givers: a warning for COVID-19 health-care givers. Acta Cardiologica, 76(2), 200-203. https://doi.org/10.1080/00015385.2020.1802903
- Di Mauro, M., Raviola, E., Guarracini, S., Di Marco, M., Lorusso, R., & Calafiore, A. M. (2021). Is surgery the fair competitor for MitraClip?Journal of Cardiac Surgery, 36(3), 1120-1122. https://doi.org/10.1111/jocs.15295
- Calafiore, A. M., Totaro, A., Guarracini, S., Prapas, S., Di Marco, M., Katsavrias, K., Gaudino, M., Lorusso, R., & Di Mauro, M. (2021). Patient-prosthesis mismatch is a preventable disease but how to prevent it is a story not yet written. Journal of Cardiac Surgery, 36(3), 978-980. https://doi.org/10.1111/jocs.15317
- Lorusso, R., Combes, A., Coco, V. L., De Piero, M. E., Belohlavek, J., Delnoij, T., van der Horst, I., Miranda, D. R., van der Linden, M., van der Heijden, J. J., Scholten, E., Haren, N. V., Lagrand, W., de Jong, S., Candura, D., Maas, J., van den Berg, M. J. V., Malfertheiner, M., Dreier, E., ... EuroECMO COVID-19 WorkingGroup (2021). ECMO for COVID-19 patients in Europe and Israel. Intensive Care Medicine, 47(3), 344-348. https://doi.org/10.1007/s00134-020-06272-3
- Mariani, S., Li, T., Bounader, K., Boethig, D., Schoede, A., Hanke, J. S., Michaelis, J., Napp, L. C., Berliner, D., Dogan, G., Lorusso, R., Haverich, A., & Schmitto, J. D. (2021). Sex differences in outcomes following less-invasive left ventricular assist device implantation. Annals of Cardiothoracic Surgery, 10(2), 255-268. https://doi.org/10.21037/acs-2020-cfmcs-21

Overview

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ERC Advanced Grant awarded to Prof. Andy Baker

15 April 2024

Longer and better lives for patients with atrial fibrillation

15 April 2024

Roberto Lorusso

Professor