Roberto Lorusso

Professor

Prof. Roberto Lorusso studied medicine at the University of Milan, Italy and graduated in 1987 magna cum Laude. He worked at Maastricht UMC+ in 1990 at CTC research and in 1996 and 1997 at the academic Hospital of Leuven. In 1998, he successfully obtained his PhD degree at Maastricht University (thesis titled 'Cardiac reinforcement and assistance by electrically stimulated skeletal muscle').

Currently, Prof. Roberto Lorusso is staff member at the Department of Cardiothoracic Surgery at Maastricht UMC+, Director of the Extracorporeal Life Support (ECLS) Program, Full Professor of Cardiac Surgery and ECLS at the Maastricht University and CARIM. His research group is focussed on mechanical circulatory support, minimally invasive valve surgery, coronary surgery, cardiac valve disease, extracorporeal circulation, acute myocardial infarction complications, cardiac valve disease, preclinical and clinical research.

Prof. Roberto Lorusso won the Gasperis-Donatelli Prize in 1989, a Young Investigator Award in 1995 and the Lillehei Award in 1998 by the European Association for Cardio-Thoracic Surgery.  He was Scientific Secretary of the Italian Society for Cardiac Surgery in 2007 and 2008, President of Euro-ELSO (2015-2017), and he is currently Editor-in-Chief of the Multi-Media Manual of Cardio-Thoracic Surgery as well as member of the ELSO Executive Committee.

He has almost 300 publications in PubMed, and has given more than 300 presentations at international meetings as invited speaker. He is Principal Investigator of international multicentre clinical studies and grant receiver from several funding bodies for clinical as well as pre-clinical investigations.

Department of Cardiothoracic surgery
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: D.2037
T: +31(0)43 387 60 32

  • 2022
    • Sala, A., Lorusso, R., & Alfieri, O. (2022). Isolated tricuspid valve surgery: beyond the idea of a high-mortality surgery. European Journal of Cardio-Thoracic Surgery, 62(2), Article ezac151. https://doi.org/10.1093/ejcts/ezac151
    • Sala, A., Lorusso, R., Zancanaro, E., Carino, D., Bargagna, M., Bisogno, A., Lapenna, E., Ruggeri, S., Meneghin, R., Schiavi, D., Buzzatti, N., Denti, P., Monaco, F., Agricola, E., Maisano, F., Alfieri, O., Castiglioni, A., & De Bonis, M. (2022). Mid-term outcomes of isolated tricuspid valve surgery according to preoperative clinical and functional staging. European Journal of Cardio-Thoracic Surgery, 62(2), Article ezac172. https://doi.org/10.1093/ejcts/ezac172
    • D'Alesio, M., Martucci, G., Arcadipane, A., Lorusso, R., & Amrein, K. (2022). Nutrition during extracorporeal life support: A review of pathophysiological bases and application of guidelines. Artificial Organs, 46(7), 1240-1248. https://doi.org/10.1111/aor.14215
    • Abdallah, H., Grasso, E., Abdelhamed, M. I., Ibrahim, A., Segur, M., Al Khamees, K., & Lorusso, R. (2022). Outcome of percutaneous HeartMate3 decommissioning: A single-centre experience. Artificial Organs, 46(7), 1429-1435. https://doi.org/10.1111/aor.14279
    • Mariani, S., De Piero, M. E., Ravaux, J. M., Saelmans, A., Kawczynski, M. J., van Bussel, B. C. T., Di Mauro, M., Willers, A., Swol, J., Kowalewski, M., Li, T., Delnoij, T. S. R., van der Horst, I. C. C., Maessen, J., & Lorusso, R. (2022). Temporary mechanical circulatory support for COVID-19 patients: A systematic review of literature. Artificial Organs, 46(7), 1249-1267. https://doi.org/10.1111/aor.14261
    • Pasierski, M., Staromłyński, J., Finke, J., Litwinowicz, R., Filip, G., Kowalówka, A., Wańha, W., Kołodziejczak, M., Piekuś-Słomka, N., Łoś, A., Stefaniak, S., Wojakowski, W., Jemielity, M., Rogowski, J., Deja, M., Jagielak, D., Bartus, K., Mariani, S., Li, T., ... Kowalewski, M. (2022). Clinical Insights to Complete and Incomplete Surgical Revascularization in Atrial Fibrillation and Multivessel Coronary Disease. Frontiers in Cardiovascular Medicine, 9, Article 910811. https://doi.org/10.3389/fcvm.2022.910811
    • Carino, D., Lorusso, R., Lapenna, E., Del Forno, B., Sala, A., Zancanaro, E., Ruggeri, S., Abboud, S., Schiavi, D., Ascione, G., Castiglioni, A., Alfieri, O., Maisano, F., & De Bonis, M. (2022). Commissural closure to treat severe mitral regurgitation: standing the test of time. European Journal of Cardio-Thoracic Surgery, 62(1), Article ezac135. https://doi.org/10.1093/ejcts/ezac135
    • Lorusso, R., Heuts, S., Jiritano, F., Scrofani, R., Antona, C., Actis Dato, G., Centofanti, P., Ferrarese, S., Matteuci, M., Miceli, A., Glauber, M., Vizzardi, E., Sponga, S., Vendramin, I., Garatti, A., de Vincentis, C., De Bonis, M., Ajello, S., Troise, G., ... Serraino, F. (2022). Contemporary outcomes of cardiac surgery patients supported by the intra-aortic balloon pump. Interactive Cardiovascular and Thoracic Surgery, 35(1), Article ivac091. https://doi.org/10.1093/icvts/ivac091
    • Lorusso, R., Bartlett, R. H., Shekar, K., MacLaren, G., Schmidt, M., Pellegrino, V., Meyns, B., Haft, J., Vercaemst, L., Pappalardo, F., Bermudez, C., Belohlavek, J., Hou, X., Boeken, U., Castillo, R., Donker, D. W., Abrams, D., Ranucci, M., Hryniewicz, K., ... 2021 ELSO Adult Cardiac Interim Guidelines Task Force (2022). Reply Letter to the Editor Regarding the ELSO Interim Guidelines for Veno-Arterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients. Asaio Journal, 68(6), e111-e112. https://doi.org/10.1097/MAT.0000000000001701
    • Lebowitz, S., Kowalewski, M., Raffa, G. M., Chu, D., Greco, M., Gandolfo, C., Mignosa, C., Lorusso, R., Suwalski, P., & Pilato, M. (2022). Review of Contemporary Invasive Treatment Approaches and Critical Appraisal of Guidelines on Hypertrophic Obstructive Cardiomyopathy: State-of-the-Art Review. Journal of Clinical Medicine, 11(12), Article 3405. https://doi.org/10.3390/jcm11123405
    • Di Mauro, M., Bonalumi, G., Giambuzzi, I., Dato, G. M. A., Centofanti, P., Corte, A. D., Ratta, E. D., Cugola, D., Merlo, M., Santini, F., Salsano, A., Rinaldi, M., Mancuso, S., Cappabianca, G., Beghi, C., De Vincentiis, C., Biondi, A., Livi, U., Sponga, S., ... Italian Group of Research for Outcome in Cardiac Surgery (GIROC) (2022). Similar outcome of tricuspid valve repair and replacement for isolated tricuspid infective endocarditis. Journal of Cardiovascular Medicine, 23(6), 406-413. https://doi.org/10.2459/JCM.0000000000001310
    • Matteucci, M., Ferrarese, S., Cantore, C., Mantovani, V., Pedroni, G., Cappabianca, G., Corazzari, C., Kowalewski, M., Severgnini, P., Lorusso, R., & Beghi, C. (2022). Early paravalvular leak after conventional mitral valve replacement: A single-center analysis. Journal of Cardiac Surgery, 37(6), 1559-1566. https://doi.org/10.1111/jocs.16422
    • Lorusso, R., Meani, P., Raffa, G. M., & Kowalewski, M. (2022). Extracorporeal membrane oxygenation and left ventricular unloading: What is the evidence?JTCVS Techniques, 13, 101-114. https://doi.org/10.1016/j.xjtc.2022.02.039
    • Willers, A., Swol, J., Buscher, H., McQuilten, Z., van Kuijk, S. M. J., Ten Cate, H., Rycus, P. T., McKellar, S., Lorusso, R., & Tonna, J. E. (2022). Longitudinal Trends in Bleeding Complications on Extracorporeal Life Support Over the Past Two Decades-Extracorporeal Life Support Organization Registry Analysis. Critical Care Medicine, 50(6), E569-E580. https://doi.org/10.1097/CCM.0000000000005466
    • Di Mauro, M., Cargoni, M., Liberi, R., Lorusso, R., & Calafiore, A. M. (2022). Mitral valve repair or replacement. How long is this feud to last?Journal of Cardiac Surgery, 37(6), 1599-1601. Article 16479. https://doi.org/10.1111/jocs.16479
    • Simons, J., Agricola, S., Smets, J., Metz, R., Mariani, S., Vleugels, M.-J., Smeets, R. R., van Mook, W. N. K. A., Mees, B., & Lorusso, R. (2022). Duplex Analysis of Cannulated Vessels in Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation. Medicina-Lithuania, 58(5), Article 671. https://doi.org/10.3390/medicina58050671
    • Li Bassi, G., Gibbons, K., Suen, J. Y., Dalton, H. J., White, N., Corley, A., Shrapnel, S., Hinton, S., Forsyth, S., Laffey, J. G., Fan, E., Fanning, J. P., Panigada, M., Bartlett, R., Brodie, D., Burrell, A., Chiumello, D., Elhazmi, A., Esperatti, M., ... Lorusso, R. (2022). Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis. Critical Care, 26(1), Article 141. https://doi.org/10.1186/s13054-022-03983-5
    • Lorusso, R., Kowalewski, M., Di Mauro, M., & Mariani, S. (2022). After the storm comes a calm: the (rather good) post-discharge survival of adults undergoing post-cardiotomy extracorporeal life support. European Journal of Cardio-Thoracic Surgery, 61(5), 1186-1187. https://doi.org/10.1093/ejcts/ezac094
    • Massimi, G., Matteucci, M., Kowalewski, M., Ronco, D., Chiarini, G., De Piero, M. E., Lo Coco, V., Maessen, J. G., Beghi, C., & Lorusso, R. (2022). Operative strategies for acute mitral regurgitation as a mechanical complication of myocardial infarction. Annals of Cardiothoracic Surgery, 11(3), 328-336. https://doi.org/10.21037/acs-2022-ami-0016
    • Makhoul, M., Medalion, B., Lorusso, R., & Bolotin, G. (2022). Sutureless repair of subacute left ventricular free wall rupture. Annals of Cardiothoracic Surgery, 11(3), 299-303. https://doi.org/10.21037/acs-2022-ami-26
    • Flynn, C. D., Morris, P., Manuel, L., Matteucci, M., Ronco, D., Massimi, G., Torchio, F., & Lorusso, R. (2022). Systematic review and meta-analysis of the mechanical complications of ischemic heart disease: papillary muscle rupture, left ventricle rupture and post-infarct ventricular septal defect. Annals of Cardiothoracic Surgery, 11(3), 195-209. https://doi.org/10.21037/acs-2022-ami-24
    • Lorusso, R., Lo Coco, V., Ravaux, J. M., & Mariani, S. (2022). The use of mechanical circulatory support in post-acute myocardial infarction mechanical complications. Annals of Cardiothoracic Surgery, 11(3), 325-327. https://doi.org/10.21037/acs-2021-ami-21
    • Lorusso, R., Calafiore, A. M., & Di Mauro, M. (2022). Acute infective endocarditis during COVID-19 pandemic time: The dark side of the moon. Journal of Cardiac Surgery, 37(5), 1168-1170. https://doi.org/10.1111/jocs.16281
    • Heuts, S., Adriaans, B. P., Kawczynski, M. J., Daemen, J. H. T., Natour, E., Lorusso, R., Schalla, S., Maessen, J. G., Wildberger, J. E., Jacobs, M. J., Rylski, B., & Bidar, E. (2022). Editor's Choice – Extending Aortic Replacement Beyond the Proximal Arch in Acute Type A Aortic Dissection: A Meta-Analysis of Short Term Outcomes and Long Term Actuarial Survival. European Journal of Vascular and Endovascular Surgery, 63(5), 674-687. https://doi.org/10.1016/j.ejvs.2021.12.045
    • Ronco, D., Corazzari, C., Matteucci, M., Massimi, G., Di Mauro, M., Ravaux, J. M., Beghi, C., & Lorusso, R. (2022). Effects of concomitant coronary artery bypass grafting on early and late mortality in the treatment of post-infarction mechanical complications: a systematic review and meta-analysis. Annals of Cardiothoracic Surgery, 11(3), 210-225. https://doi.org/10.21037/acs-2021-ami-19
    • Willers, A., Swol, J., von Kuijk, S. M. J., Buscher, H., McQuilten, Z., ten Cate, H., Rycus, P. T., McKellar, S., Lorusso, R., & Tonna, J. E. (2022). HEROES V-V-HEmorRhagic cOmplications in Veno-Venous Extracorporeal life Support-Development and internal validation of multivariable prediction model in adult patients. Artificial Organs, 46(5), 932-952. https://doi.org/10.1111/aor.14148
    • Torchio, F., Garatti, A., Ronco, D., Matteucci, M., Massimi, G., & Lorusso, R. (2022). Left ventricular pseudoaneurysm: the niche of post-infarction mechanical complications. Annals of Cardiothoracic Surgery, 11(3), 290-298. https://doi.org/10.21037/acs-2022-ami-25
    • Lorusso, R., Ronco, D., Massimi, G., Di Mauro, M., Jiritano, F., & Matteucci, M. (2022). Managing and repairing ventricular free-wall rupture: the triple-patch technique. Annals of Cardiothoracic Surgery, 11(3), 346-348. https://doi.org/10.21037/acs-2021-ami-22
    • Rahouma, M., Baudo, M., Shmushkevich, S., Chadow, D., Mohamed, A., Girardi, L., Gaudino, M., & Lorusso, R. (2022). Sex differences in primary malignant cardiac tumors: A multi-institutional cohort study from National Cancer Database. Journal of Cardiac Surgery, 37(5), 1275-1286. https://doi.org/10.1111/jocs.16359
    • Matteucci, M., Ronco, D., Ravaux, J. M., Massimi, G., Di Mauro, M., Houterman, S., Maessen, J., Beghi, C., Severgnini, P., Lorusso, R., & Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration (2022). Surgical repair of post-infarction ventricular free-wall rupture in the Netherlands: data from a nationwide registry. Annals of Cardiothoracic Surgery, 11(3), 310-318. https://doi.org/10.21037/acs-2021-ami-10
    • Massimi, G., Matteucci, M., Kowalewski, M., Ronco, D., Jiritano, F., Beghi, C., Severgnini, P., & Lorusso, R. (2022). Surgical treatment of post-infarction papillary muscle rupture: systematic review and meta-analysis. Annals of Cardiothoracic Surgery, 11(3), 252-260. https://doi.org/10.21037/acs-2021-ami-15
    • Condello, I., Lorusso, R., Santarpino, G., Fiore, F., Nasso, G., & Speziale, G. (2022). Clinical Evaluation of Micro-Embolic Activity with Unexpected Predisposing Factors and Performance of Horizon AF PLUS during Cardiopulmonary Bypass. Membranes, 12(5), Article 465. https://doi.org/10.3390/membranes12050465
    • Sala, A., Lorusso, R., & Alfieri, O. (2022). Isolated tricuspid regurgitation: A plea for early correction. International Journal of Cardiology, 353, 80-85. https://doi.org/10.1016/j.ijcard.2022.01.069
    • D'Auria, F., Santo, D. F., Myat, A., Lorusso, R., Ravaux, J. M., Trivedi, U., & Hildick-Smith, D. (2022). Apical versus subclavian transcatheter aortic valve implantation: An 8-year United Kingdom analysis. Journal of Cardiac Surgery, 37(4), 978-984. https://doi.org/10.1111/jocs.16298
    • Di Nardo, M., De Piero, M. E., Hoskote, A., Belohlavek, J., Lorusso, R., & EuroECMO neonatal and paediatric COVID-19 Working Group and EuroELSO Steering Committee (2022). Extracorporeal membrane oxygenation in children with COVID-19 and PIMS-TS during the second and third wave. Lancet child & adolescent health, 6(4), E14-E15. https://doi.org/10.1016/s2352-4642(22)00065-7
    • Squiccimarro, E., Stasi, A., Lorusso, R., & Paparella, D. (2022). Narrative review of the systemic inflammatory reaction to cardiac surgery and cardiopulmonary bypass. Artificial Organs, 46(4), 568-577. https://doi.org/10.1111/aor.14171
    • Wang, L., Yang, F., Zhang, S., Li, C., Du, Z., Rycus, P., Tonna, J. E., Alexander, P., Lorusso, R., Fan, E., Ogino, M., Brodie, D., Combes, A., Chen, Y.-S., Qiu, H., Peng, Z., Fraser, J. F., Shao, J., Jia, M., ... Hou, X. (2022). Percutaneous versus surgical cannulation for femoro-femoral VA-ECMO in patients with cardiogenic shock: Results from the Extracorporeal Life Support Organization Registry. Journal of Heart and Lung Transplantation, 41(4), 470-481. https://doi.org/10.1016/j.healun.2022.01.009
    • Di Mauro, M., Bonalumi, G., Calafiore, A. M., & Lorusso, R. (2022). Valve endocarditis, to repair or not to repair, is that really the question?Journal of Cardiac Surgery, 37(4), 1016-1018. https://doi.org/10.1111/jocs.16232
    • Condello, I., Lorusso, R., Santarpino, G., Di Bari, N., Fiore, F., Moscarelli, M., Calafiore, A. M., Speziale, G., & Nasso, G. (2022). Perioperative incidence of ECMO and IABP on 5901 mitral valve surgery procedures. Journal of Cardiothoracic Surgery, 17(1), Article 38. https://doi.org/10.1186/s13019-022-01790-1
    • Sciatti, E., Mohseni, Z., Orabona, R., Mulder, E. G., Prefumo, F., Lorusso, R., Frusca, T., Spaanderman, M. E. A., & Ghossein-Doha, C. (2022). Inappropriate left ventricular mass after HELLP syndrome inappropriate LVM after HELLP syndrome. Pregnancy Hypertension, 27, 16-22. https://doi.org/10.1016/j.preghy.2021.11.003
    • Heuts, S., Makhoul, M., Mansouri, A. N., Taccone, F. S., Obeid, A., Belliato, M., Broman, L. M., Malfertheiner, M., Meani, P., Raffa, G. M., Delnoij, T., Maessen, J., Bolotin, G., & Lorusso, R. (2022). Defining and understanding the "extra-corporeal membrane oxygenation gap" in the veno-venous configuration: Timing and causes of death. Artificial Organs, 46(3), 349-361. https://doi.org/10.1111/aor.14058
    • Matteucci, M., Ronco, D., Massimi, G., Di Mauro, M., & Lorusso, R. (2022). Le complicanze meccaniche dell’infarto miocardico acuto: dalla diagnosi al trattamento. Giornale Italiano di Cardiologia, 23(3), 190-199. https://doi.org/10.1714/3751.37338
    • Ronco, D., Matteucci, M., Massimi, G., Di Mauro, M., & Lorusso, R. (2022). Postinfarction ventricular septal rupture repair: Is it just a matter of the surgical technique?Journal of Cardiac Surgery, 37(3), 524-525. https://doi.org/10.1111/jocs.16149
    • Fischlein, T., Caporali, E., Asch, F. M., Vogt, F., Pollari, F., Folliguet, T., Kappert, U., Meuris, B., Shrestha, M. L., Roselli, E. E., Bonaros, N., Fabre, O., Corbi, P., Troise, G., Andreas, M., Pinaud, F., Pfeiffer, S., Kueri, S., Tan, E., ... Lorusso, R. (2022). Hemodynamic Performance of Sutureless vs. Conventional Bioprostheses for Aortic Valve Replacement: The 1-Year Core-Lab Results of the Randomized PERSIST-AVR Trial. Frontiers in Cardiovascular Medicine, 9, Article 844876. https://doi.org/10.3389/fcvm.2022.844876
    • Moscarelli, M., Lorusso, R., Angelini, G. D., Di Bari, N., Paparella, D., Fattouch, K., Albertini, A., Nasso, G., Fiorentino, F., & Speziale, G. (2022). Sex-specific differences and postoperative outcomes of minimally invasive and sternotomy valve surgery. European Journal of Cardio-Thoracic Surgery, 61(3), 695-702. https://doi.org/10.1093/ejcts/ezab369
    • Rahouma, M., Baudo, M., Shmushkevich, S., Chadow, D., Mohamed, A., Gaudino, M., & Lorusso, R. (2022). Association between insurance status and survival among patients with malignant cardiac tumours. British Journal of Surgery, 109(2), E24-E25. Article 423. https://doi.org/10.1093/bjs/znab423
    • Meani, P., Lorusso, R., & Pappalardo, F. (2022). ECPella: Concept, Physiology and Clinical Applications. Journal of Cardiothoracic and Vascular Anesthesia, 36(2), 557-566. https://doi.org/10.1053/j.jvca.2021.01.056
    • Ravaux, J. M., Van Kuijk, S. M. J., Di Mauro, M., Vernooy, K., Bidar, E., Van't Hof, A. W., Veenstra, L., Kats, S., Houterman, S., Maessen, J. G., Lorusso, R., & THI Registration Committee of The Netherlands Heart Registration (2022). Incidence and Predictors of Permanent Pacemaker Implantation after Transcatheter Aortic Valve Procedures: Data of The Netherlands Heart Registration (NHR). Journal of Clinical Medicine, 11(3), Article 560. https://doi.org/10.3390/jcm11030560
    • Raasveld, S. J., Karami, M., van den Bergh, W. M., Lansink-Hartgring, A. O., van der Velde, F., Maas, J. J., van de Berg, P., de Haan, M., Lorusso, R., Delnoij, T. S. R., Miranda, D. D., Mandigers, L., Scholten, E., Overmars, M., Taccone, F. S., Brasseur, A., Dauwe, D. F., De Troy, E., Hermans, G., ... Vlaar, A. P. J. (2022). RBC Transfusion in Venovenous Extracorporeal Membrane Oxygenation: A Multicenter Cohort Study. Critical Care Medicine, 50(2), 224-234. https://doi.org/10.1097/CCM.0000000000005398
    • Massimi, G., Ronco, D., De Bonis, M., Kowalewski, M., Formica, F., Russo, C. F., Sponga, S., Vendramin, I., Falcetta, G., Fischlein, T., Troise, G., Trumello, C., Actis Dato, G., Carrozzini, M., Shah, S. H., Coco, V. L., Villa, E., Scrofani, R., Torchio, F., ... Lorusso, R. (2022). Surgical treatment for post-infarction papillary muscle rupture: a multicentre study. European Journal of Cardio-Thoracic Surgery, 61(2), 469-476. https://doi.org/10.1093/ejcts/ezab469