Roberto Lorusso

Professor

Prof. Roberto Lorusso studied medicine at the University of Milan, Italy and graduated in 1987 magna cum Laude. He worked at Maastricht UMC+ in 1990 at CTC research and in 1996 and 1997 at the academic Hospital of Leuven. In 1998, he successfully obtained his PhD degree at Maastricht University (thesis titled 'Cardiac reinforcement and assistance by electrically stimulated skeletal muscle').

Currently, Prof. Roberto Lorusso is staff member at the Department of Cardiothoracic Surgery at Maastricht UMC+, Director of the Extracorporeal Life Support (ECLS) Program, Full Professor of Cardiac Surgery and ECLS at the Maastricht University and CARIM. His research group is focussed on mechanical circulatory support, minimally invasive valve surgery, coronary surgery, cardiac valve disease, extracorporeal circulation, acute myocardial infarction complications, cardiac valve disease, preclinical and clinical research.

Prof. Roberto Lorusso won the Gasperis-Donatelli Prize in 1989, a Young Investigator Award in 1995 and the Lillehei Award in 1998 by the European Association for Cardio-Thoracic Surgery.  He was Scientific Secretary of the Italian Society for Cardiac Surgery in 2007 and 2008, President of Euro-ELSO (2015-2017), and he is currently Editor-in-Chief of the Multi-Media Manual of Cardio-Thoracic Surgery as well as member of the ELSO Executive Committee.

He has almost 300 publications in PubMed, and has given more than 300 presentations at international meetings as invited speaker. He is Principal Investigator of international multicentre clinical studies and grant receiver from several funding bodies for clinical as well as pre-clinical investigations.

Department of Cardiothoracic surgery
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: D.2037
T: +31(0)43 387 60 32

  • 2021
    • Di Nardo, M., Annoni, F., Su, F. H., Belliato, M., Lorusso, R., Broman, L. M., Malfertheiner, M., Creteur, J., & Taccone, F. S. (2021). Evaluation of a New Extracorporeal CO2 Removal Device in an Experimental Setting. Membranes, 11(1), Article 8. https://doi.org/10.3390/membranes11010008
    • Martucci, G., Arcadipane, A., Tuzzolino, F., Occhipinti, G., Panarello, G., Carcione, C., Bonicolini, E., Vitiello, C., Lorusso, R., Conaldi, P. G., & Miceli, V. (2021). Identification of a Circulating miRNA Signature to Stratify Acute Respiratory Distress Syndrome Patients. Journal of Personalized Medicine, 11(1), Article 15. https://doi.org/10.3390/jpm11010015
    • Belliato, M., Epis, F., Cremascoli, L., Ferrari, F., Quattrone, M. G., Fisser, C., Malfertheiner, M. V., Taccone, F. S., Di Nardo, M., Broman, L. M., & Lorusso, R. (2021). Mechanical Power during Veno-Venous Extracorporeal Membrane Oxygenation Initiation: A Pilot-Study. Membranes, 11(1), Article 30. https://doi.org/10.3390/membranes11010030
    • Kowalewski, M., Zielinski, K., Raffa, G. M., Meani, P., Lo Coco, V., Jiritano, F., Fina, D., Matteucci, M., Chiarini, G., Willers, A., Simons, J., Suwalski, P., Gaudino, M., Di Mauro, M., Maessen, J., & Lorusso, R. (2021). Mortality Predictors in Elderly Patients With Cardiogenic Shock on Venoarterial Extracorporeal Life Support. Analysis From the Extracorporeal Life Support Organization Registry*. Critical Care Medicine, 49(1), 7-18. https://doi.org/10.1097/CCM.0000000000004695
    • Lorusso, R., Ravaux, J. M., Barili, F., Bidar, E., Vernooy, K., Di Mauro, M., Miceli, A., Parolari, A., Daprati, A., Myasoedova, V., Alamanni, F., De Vincentiis, C., Aime, E., Nicolini, F., Gonzi, G., Colli, A., Gerosa, G., De Bonis, M., Paglino, G., ... GIROC Investigators (2021). Relation of Prolonged Pacemaker Dependency After Cardiac Surgery to Mortality. American Journal of Cardiology, 138, 66-71. https://doi.org/10.1016/j.amjcard.2020.10.010
    • Cho, S. M., Canner, J., Caturegli, G., Choi, C. W., Etchill, E., Giuliano, K., Chiarini, G., Calligy, K., Rycus, P., Lorusso, R., Kim, B. S., Sussman, M., Suarez, J. I., Geocadin, R., Bush, E. L., Ziai, W., & Whitman, G. (2021). Risk Factors of Ischemic and Hemorrhagic Strokes During Venovenous Extracorporeal Membrane Oxygenation: Analysis of Data From the Extracorporeal Life Support Organization Registry. Critical Care Medicine, 49(1), 91-101. https://doi.org/10.1097/CCM.0000000000004707
    • Lorusso, R., Whitman, G., Milojevic, M., Raffa, G., McMullan, D. M., Boeken, U., Haft, J., Bermudez, C. A., Shah, A. S., & D'Alessandro, D. A. (2021). 2020 EACTS/ELSO/STS/AATS Expert Consensus on Post-cardiotomy Extracorporeal Life Support in Adult Patients. Asaio Journal, 67(1), E1-E43. https://doi.org/10.1097/MAT.0000000000001301
    • Holtackers, R. J., Ter Bekke, R. M. A., Bijvoet, G. P., Gommers, S., Chiribiri, A., & Lorusso, R. (2021). A Boolean Dilemma: True or False Aneurysm?JACC. Case reports, 3(1), 112-116. https://doi.org/10.1016/j.jaccas.2020.09.055
    • Simons, J., Suverein, M., van Mook, W., Caliskan, K., Soliman, O., van de Poll, M., Delnoij, T., Maessen, J., Mees, B., & Lorusso, R. (2021). Do-(Not-)Mechanical-Circulatory-Support Orders: Should We Ask All Cardiac Surgery Patients for Informed Consent for Post-Cardiotomy Extracorporeal Life Circulatory Support?Journal of Clinical Medicine, 10(3), Article 383. https://doi.org/10.3390/jcm10030383
    • Matteucci, M., & Lorusso, R. (2021). Left ventricular venting for extracorporeal life support in pheochromocytoma: Letter to the Editor - response. Perfusion, 36(1), 105-106. Article 0267659120966916. https://doi.org/10.1177/0267659120966916
    • Calafiore, A. M., Totaro, A., Testa, N., Sacra, C., Castellano, G., Guarracini, S., Di Marco, M., Prapas, S., Gaudino, M., Lorusso, R., Paparella, D., & Di Mauro, M. (2021). The secret life of the mitral valve. Journal of Cardiac Surgery, 36(1), 247-259. https://doi.org/10.1111/jocs.15151
    • Bonelli, A., Lorusso, R., Paris, S., Troise, G., Mohammed, A., Bursi, F., & Faggiano, P. (2021). Active cancer and cardiac surgery: Possible scenarios in patient decision-making. Monaldi Archives for Chest Disease, 91(1), Article 1655. https://doi.org/10.4081/monaldi.2021.1655
    • Meani, P., Mlcek, M., Kowalewski, M., Raffa, G. M., Popkova, M., Pilato, M., Arcadipane, A., Belohlavek, J., & Lorusso, R. (2021). Transaortic or Pulmonary Artery Drainage for Left Ventricular Unloading in Venoarterial Extracorporeal Life Support: A Porcine Cardiogenic Shock Model. Seminars in Thoracic and Cardiovascular Surgery, 33(3), 724-732. https://doi.org/10.1053/j.semtcvs.2020.11.001
  • 2020
    • Zakhary, B., Vercaemst, L., Mason, P., Antonini, M. V., Lorusso, R., & Brodie, D. (2020). How I approach membrane lung dysfunction in patients receiving ECMO. Critical Care, 24(1), Article 671. https://doi.org/10.1186/s13054-020-03388-2
    • D'Auria, F., Casado, A. P., Myat, A., Lorusso, R., & Hildick-Smith, D. (2020). Long-Term Survival and Outcomes According to VARC-2 Criteria for Subclavian, Direct Aortic, Femoral, and Apical Implantation: An 8-Year United Kingdom TAVI Surgical Experience. Surgical Technology International, 37, 245-252. https://pubmed.ncbi.nlm.nih.gov/32819023/
    • Wengenmayer, T., Muellenbach, R. M., Taccone, F. S., Kredel, M., Kalenka, A., Belohlavek, J., Spangenberg, T., Haake, H., Bracht, H., Moerer, O., Lorusso, R., & Lepper, P. M. (2020). Extracorporeal Membrane Oxygenation for Critically Ill Patients with COVID-19-related Acute Respiratory Distress Syndrome: Worth the Effort!American Journal of Respiratory and Critical Care Medicine, 202(10), 1477-1479. https://doi.org/10.1164/rccm.202006-2505LE
    • Bonaros, N., Czerny, M., Pfausler, B., Muller, S., Bartel, T., Thielmann, M., Shehada, S. E., Folliguet, T., Obadia, J. F., Holfeld, J., Lorusso, R., Parolari, A., Muller, L., Grimm, M., & Ruttmann-Ulmer, E. (2020). Infective endocarditis and neurologic events: indications and timing for surgical interventions. European Heart Journal Supplements, 22(M), M19-M25. https://doi.org/10.1093/eurheartj/suaa167
    • Swol, J., Shigemura, N., Ichiba, S., Steinseifer, U., Anraku, M., & Lorusso, R. (2020). Artificial lungs--Where are we going with the lung replacement therapy?Artificial Organs, 44(11), 1135-1149. https://doi.org/10.1111/aor.13801
    • Broman, L. M., Westlund, C. J., Gilbers, M., da Camara, L. P., Wittberg, L. P., Taccone, F. S., Malfertheiner, M., Di Nardo, M., Swol, J., Vercaemst, L., Barrett, N. A., Pappalardo, F., Belohlavek, J., Belliato, M., & Lorusso, R. (2020). Pressure and flow properties of dual-lumen cannulae for extracorporeal membrane oxygenation. Perfusion, 35(8), 736-744. Article 0267659120926009. https://doi.org/10.1177/0267659120926009
    • Amata, M., Martucci, G., Granata, A., Tuzzolino, F., Panarello, G., Bianco, C., Lorusso, R., Traina, M., & Arcadipane, A. (2020). The role of endoscopy as non-invasive procedure to manage gastrointestinal complications during extracorporeal membrane oxygenation. Perfusion, 35(8), 786-794. https://doi.org/10.1177/0267659120909669
    • Brogan, T., Thiagarajan, R. R., Lorusso, R., McMullan, D. M., Di Nardo, M., Ogino, M. T., Dalton, H. J., Burke, C. R., & Capatos, G. (2020). The use of extracorporeal membrane oxygenation in human immunodeficiency virus-positive patients: a review of a multicenter database. Perfusion, 35(8), 772-777. https://doi.org/10.1177/0267659120906966
    • Di Mauro, M., Dato, G. A., Sponga, S., & Lorusso, R. (2020). Timing chirurgico nell’endocardite infettiva valvolare. Giornale Italiano di Cardiologia, 21(11), 890-895. https://doi.org/10.1714/3455.34443
    • Barbaro, R. P., MacLaren, G., Boonstra, P. S., Iwashyna, T. J., Slutsky, A. S., Fan, E., Bartlett, R. H., Tonna, J. E., Hyslop, R., Fanning, J. J., Rycus, P. T., Hyer, S. J., Anders, M. M., Agerstrand, C. L., Hryniewicz, K., Diaz, R., Lorusso, R., Combes, A., Brodie, D., & Extracorporeal Life Support Organization (2020). Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry. Lancet, 396(10257), 1071-1078. https://doi.org/10.1016/s0140-6736(20)32008-0
    • Orabona, R., Mohseni, Z., Sciatti, E., Mulder, E. G., Prefumo, F., Lorusso, R., Frusca, T., Ghossein-Doha, C., & Spaanderman, M. E. A. (2020). Maternal myocardial dysfunction after normotensive fetal growth restriction compared with hypertensive pregnancies: a speckle-tracking study. Journal of Hypertension, 38(10), 1955-1963. https://doi.org/10.1097/HJH.0000000000002496
    • Mariani, S., Richter, J., Pappalardo, F., Belohlavek, J., Lorusso, R., Schmitto, J. D., Bauersachs, J., & Napp, L. C. (2020). Mechanical circulatory support for Takotsubo syndrome: a systematic review and meta-analysis. International Journal of Cardiology, 316, 31-39. https://doi.org/10.1016/j.ijcard.2020.05.033
    • Calafiore, A. M., Di Mauro, M., Bonatti, J., Centofanti, P., Di Eusanio, M., Faggian, G., Fattouch, K., Gaudino, M., Kofidis, T., Lorusso, R., Menicanti, L., Prapas, S., Sarkar, K., Stefano, P., Tabata, M., Zenati, M., & Paparella, D. (2020). An observational, prospective study on surgical treatment of secondary mitral regurgitation: The SMR study. Rationale, purposes, and protocol. Journal of Cardiac Surgery, 35(10), 2489-2494. https://doi.org/10.1111/jocs.14924
    • Cho, S.-M., Canner, J., Chiarini, G., Calligy, K., Caturegli, G., Rycus, P., Barbaro, R. P., Tonna, J., Lorusso, R., Kilic, A., Choi, C. W., Ziai, W., Geocadin, R., & Whitman, G. (2020). Modifiable Risk Factors and Mortality From Ischemic and Hemorrhagic Strokes in Patients Receiving Venoarterial Extracorporeal Membrane Oxygenation: Results From the Extracorporeal Life Support Organization Registry. Critical Care Medicine, 48(10), E897-E905. https://doi.org/10.1097/CCM.0000000000004498
    • Streng, A. S., Delnoij, T. S. R., Mulder, M. M. G., Sels, J. W. E. M., Wetzels, R. J. H., Verhezen, P. W. M., Olie, R. H., Kooman, J. P., van Kuijk, S. M. J., Brandts, L., Ten Cate, H., Lorusso, R., van der Horst, I. C. C., van Bussel, B. C. T., & Henskens, Y. M. C. (2020). Monitoring of Unfractionated Heparin in Severe COVID-19: An Observational Study of Patients on CRRT and ECMO. TH open : companion journal to thrombosis and haemostasis, 4(4), e365-e375. https://doi.org/10.1055/s-0040-1719083
    • Sponga, S., Di Mauro, M., Malvindi, P. G., Paparella, D., Murana, G., Pacini, D., Weltert, L., De Paulis, R., Cappabianca, G., Beghi, C., De Vincentiis, C., Parolari, A., Messina, A., Troise, G., Salsano, A., Santini, F., Pierri, M. D., Di Eusanio, M., Maselli, D., ... Italian Group of Research for Outcome in Cardiac Surgery (GIROC) (2020). Surgery for Bentall endocarditis: short- and midterm outcomes from a multicentre registry. European Journal of Cardio-Thoracic Surgery, 58(4), 839-846. https://doi.org/10.1093/ejcts/ezaa136
    • Di Mauro, M., Lorusso, R., Parolari, A., & Calafiore, A. M. (2020). Commentary: Awide road is better than a simple bridge. JTCVS Techniques, 3, 179-180. https://doi.org/10.1016/j.xjtc.2020.04.016
    • Matteucci, M., Fina, D., Jiritano, F., Meani, P., Raffa, G. M., Kowalewski, M., Aldobayyan, I., Turkistani, M., Beghi, C., & Lorusso, R. (2020). The use of extracorporeal membrane oxygenation in the setting of postinfarction mechanical complications: outcome analysis of the Extracorporeal Life Support Organization Registry. Interactive Cardiovascular and Thoracic Surgery, 31(3), 369-374. https://doi.org/10.1093/icvts/ivaa108
    • Swol, J., & Lorusso, R. (2020). Additive treatment considerations in COVID-19-The clinician's perspective on extracorporeal adjunctive purification techniques. Artificial Organs, 44(9), 918-925. https://doi.org/10.1111/aor.13748
    • Piacente, C., Martucci, G., Miceli, V., Pavone, G., Papeo, A., Occhipinti, G., Panarello, G., Lorusso, R., Tanaka, K., & Arcadipane, A. (2020). A narrative review of antithrombin use during veno-venous extracorporeal membrane oxygenation in adults: rationale, current use, effects on anticoagulation, and outcomes. Perfusion, 35(6), 452-464. https://doi.org/10.1177/0267659120913803
    • Fina, D., Matteucci, M., Jiritano, F., Meani, P., Lo Coco, V., Kowalewski, M., Maessen, J., Guazzi, M., Ballotta, A., Ranucci, M., & Lorusso, R. (2020). Extracorporeal membrane oxygenation without therapeutic anticoagulation in adults: A systematic review of the current literature. International Journal of Artificial Organs, 43(9), 570-578. https://doi.org/10.1177/0391398820904372
    • Kowalewski, M., Gozdek, M., Zielinski, K., Raffa, G. M., Suwalski, P., & Lorusso, R. (2020). Long-term mortality after percutaneous coronary intervention with drug-eluting stents compared with coronary artery bypass grafting for multivessel and left main disease: a meta-analysis. Kardiologia Polska, 78(7-8), 759-761. https://doi.org/10.33963/KP.15397
    • Abrams, D., Lorusso, R., Vincent, J.-L., & Brodie, D. (2020). ECMO during the COVID-19 pandemic: when is it unjustified?Critical Care, 24(1), Article 507. https://doi.org/10.1186/s13054-020-03230-9
    • Squiccimarro, E., Rociola, R., Haumann, R. G., Grasso, S., Lorusso, R., & Paparella, D. (2020). Extracorporeal Oxygenation and Coronavirus Disease 2019 Epidemic: Is the Membrane Fail-Safe to Cross Contamination?Asaio Journal, 66(8), 841-843. https://doi.org/10.1097/MAT.0000000000001199
    • Jiritano, F., Lorusso, R., & Santarpino, G. (2020). Causes of Thrombocytopenia in Cardiac Surgery: Looking for the Holy Grail?Annals of Thoracic Surgery, 110(2), 751-752. https://doi.org/10.1016/j.athoracsur.2020.01.018
    • Ong, J., Zhang, J. J. Y., Lorusso, R., MacLaren, G., & Ramanathan, K. (2020). Extracorporeal membrane oxygenation in pregnancy and the postpartum period: a systematic review of case reports. International Journal of Obstetric Anesthesia, 43, 106-113. https://doi.org/10.1016/j.ijoa.2020.04.004
    • Calafiore, A. M., Lorusso, R., Kheirallah, H., Alsaied, M. M., Alfonso, J. J. R. A., Di Baldassare, A., Gallina, S., Gaudino, M., & Di Mauro, M. (2020). Late tricuspid regurgitation and right ventricular remodeling after tricuspid annuloplasty. Journal of Cardiac Surgery, 35(8), 1891-1900. https://doi.org/10.1111/jocs.14840
    • Worku, E., Gill, D., Brodie, D., Lorusso, R., Combes, A., & Shekar, K. (2020). Provision of ECPR during COVID-19: evidence, equity, and ethical dilemmas. Critical Care, 24(1), Article 462. https://doi.org/10.1186/s13054-020-03172-2
    • Olson, T. L., O'Neil, E. R., Ramanathan, K., Lorusso, R., MacLaren, G., & Anders, M. M. (2020). Extracorporeal membrane oxygenation in peripartum cardiomyopathy: A review of the ELSO Registry. International Journal of Cardiology, 311, 71-76. https://doi.org/10.1016/j.ijcard.2020.03.006
    • Suverein, M. M., Delnoij, T. S. R., Lorusso, R., Bol, M. E., Weerwind, P. W., Roekaerts, P. M. H. J., Maessen, J. G., & van de Poll, M. C. G. (2020). National and reporting differences of pre-hospital factors in extracorporeal cardiopulmonary resuscitation studies. Netherlands Journal of Critical Care, 28(4), 154-161. https://njcc.nl/artikel/3404
    • Shekar, K., Badulak, J., Peek, G., Boeken, U., Dalton, H. J., Arora, L., Zakhary, B., Ramanathan, K., Starr, J., Akkanti, B., Antonini, M. V., Ogino, M. T., Raman, L., Barret, N., Brodie, D., Combes, A., Lorusso, R., MacLaren, G., Müller, T., ... ELSO Guideline Working Group (2020). Extracorporeal Life Support Organization Coronavirus Disease 2019 Interim Guidelines: A Consensus Document from an International Group of Interdisciplinary Extracorporeal Membrane Oxygenation Providers. Asaio Journal, 66(7), 707-721. https://doi.org/10.1097/MAT.0000000000001193
    • Lorusso, R., Di Mauro, M., Foschi, M., & Calafiore, A. M. (2020). Commentary: Mater artium necessitas (necessity is the mother of invention) Comment. JTCVS Techniques, 2, 86-87. https://doi.org/10.1016/j.xjtc.2020.03.018
    • Mariani, S., Napp, L. C., Lo Coco, V., Delnoij, T. S. R., Luermans, J. G. L. M., ter Bekke, R. M. A., Timmermans, C., Li, T., Dogan, G., Schmitto, J. D., Maessen, J., Maesen, B., & Lorusso, R. (2020). Mechanical circulatory support for life -threatening arrhythmia: A systematic review. International Journal of Cardiology, 308, 42-49. https://doi.org/10.1016/j.ijcard.2020.03.045
    • Konstantinides, S., Meyer, G., Becattini, C., Bueno, H., Geersing, G.-J., Harjola, V.-P., Huisman, M., Humbert, M., Jennings, C. S., Jimenez, D., Kucher, N., Lang, I. M., Lankeit, M., Lorusso, R., Mazzolai, L., Meneveau, N., Ainle, F. N., Prandoni, P., Pruszczyk, P., ... ESC Scientific Document Group (2020). Guía ESC 2019 para el diagnóstico y tratamiento de la embolia pulmonar aguda. Revista Espanola de Cardiologia, 73(6), 497.e1-497.e58. https://doi.org/10.1016/j.recesp.2019.12.030
    • Lorusso, R., Miceli, A., Gelsomino, S., Lio, A., Parise, O., Montisci, A., Vizzardi, E., Pacini, D., Di Bartolomeo, R., Renzulli, A., Serraino, F. G., Comoglio, C., Liberi, R., Martinelli, G., Sciangula, A., Mazzola, A., Faragalli, F., De Bonis, M., Taramasso, M., ... Glauber, M. (2020). Mitral Valve Replacement with a Third Generation Porcine Valve: an Italian Multicentered Study. Annals of Thoracic Surgery, 109(6), 1865-1872. https://doi.org/10.1016/j.athoracsur.2019.08.111