Roberto Lorusso

Professor

Prof. Roberto Lorusso studied medicine at the University of Milan, Italy and graduated in 1987 magna cum Laude. He worked at Maastricht UMC+ in 1990 at CTC research and in 1996 and 1997 at the academic Hospital of Leuven. In 1998, he successfully obtained his PhD degree at Maastricht University (thesis titled 'Cardiac reinforcement and assistance by electrically stimulated skeletal muscle').

Currently, Prof. Roberto Lorusso is staff member at the Department of Cardiothoracic Surgery at Maastricht UMC+, Director of the Extracorporeal Life Support (ECLS) Program, Full Professor of Cardiac Surgery and ECLS at the Maastricht University and CARIM. His research group is focussed on mechanical circulatory support, minimally invasive valve surgery, coronary surgery, cardiac valve disease, extracorporeal circulation, acute myocardial infarction complications, cardiac valve disease, preclinical and clinical research.

Prof. Roberto Lorusso won the Gasperis-Donatelli Prize in 1989, a Young Investigator Award in 1995 and the Lillehei Award in 1998 by the European Association for Cardio-Thoracic Surgery. He was Scientific Secretary of the Italian Society for Cardiac Surgery in 2007 and 2008, President of Euro-ELSO (2015-2017), and he is currently Editor-in-Chief of the Multi-Media Manual of Cardio-Thoracic Surgery as well as member of the ELSO Executive Committee.

He has almost 300 publications in PubMed, and has given more than 300 presentations at international meetings as invited speaker. He is Principal Investigator of international multicentre clinical studies and grant receiver from several funding bodies for clinical as well as pre-clinical investigations.

Department of Cardiothoracic surgery
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
Room number: D.2037
T: +31(0)43 387 60 32

2018
- Brasseur, A., Scolletta, S., Lorusso, R., & Taccone, F. S. (2018). Hybrid extracorporeal membrane oxygenation. Journal of Thoracic Disease, 10, S707-S715. https://doi.org/10.21037/jtd.2018.03.84
- de Jong, M. M., Lorusso, R., Al Awami, F., Matteuci, F., Parise, O., Lozekoot, P., Bonacchi, M., Maessen, J. G., Johnson, D. M., & Gelsomino, S. (2018). Vascular complications following intra-aortic balloon pump implantation: an updated review. Perfusion, 33(2), 96-104. https://doi.org/10.1177/0267659117727825
- Piciche, M., Dato, G. A., Lorusso, R., & Musumeci, F. (2018). A Review of Evolutionary and Cyclical Changes in the Surgical Approach to Aortic Valve Disease. Reviews on Recent Clinical Trials, 13(1), 45-51. https://doi.org/10.2174/1574887112666171009165609
2017
- Gaudino, M., Alexander, J. H., Bakaeen, F. G., Ballman, K., Barili, F., Calafiore, A. M., Davierwala, P., Goldman, S., Kappetein, P., Lorusso, R., Mylotte, D., Pagano, D., Ruel, M., Schwann, T., Suma, H., Taggart, D. P., Tranbaugh, R. F., & Fremes, S. (2017). Randomized comparison of the clinical outcome of single versus multiple arterial grafts: the ROMA trial-rationale and study protocol. European Journal of Cardio-Thoracic Surgery, 52(6), 1031-1040. https://doi.org/10.1093/ejcts/ezx358
- Lorusso, R., Taccone, F. S., Beliato, M., Delnoij, T., Zanatta, P., Cvetkovic, M., Davidson, M., Belohlavek, J., Matta, N., Davis, C., Ijsselstijn, H., Mueller, T., Muelenbach, R., Donker, D., David, P., Di Nardo, M., Vlasselaers, D., dos Reis Miranda, D., Hoskote, A., & Euro-ELSO Working Grp Neurologic M (2017). Brain monitoring in adult and pediatric ECMO patients: the importance of early and late assessments. Minerva Anestesiologica, 83(10), 1061-1074. https://doi.org/10.23736/S0375-9393.17.11911-5
- Lorusso, R. (2017). Extracorporeal life support and neurologic complications: still a long way to go. Journal of Thoracic Disease, 9(10), E954-E956. https://doi.org/10.21037/jtd.2017.09.30
- Raffa, G. M., Gelsomino, S., Sluijpers, N., Meani, P., Alenizy, K., Natour, E., Bidar, E., Johnson, D. M., Makhoul, M., Heuts, S., Lozekoot, P., Kats, S., Schreurs, R., Delnoij, T., Montalti, A., Sels, J. W., Poll, M. V. D., Roekaerts, P., Maessen, J., & Lorusso, R. (2017). In-hospital outcome of post-cardiotomy extracorporeal life support in adult patients: the 2007-2017 Maastricht experience. Critical Care and Resuscitation, 19(Suppl 1), 53-61. http://cicm.org.au/CICM_Media/CICMSite/CICM-Website/Resources/Publications/CCR%20Journal/Previous%20Editions/October%20Supplement%202017/ccr_19_OctSupp_011017-S53-S61.pdf
- Lorusso, R., & Gelsomino, S. (2017). Mitral valve repair for functional regurgitation: Do not miss the last piece of the puzzle!Journal of Thoracic and Cardiovascular Surgery, 154(4), 1258-1259. https://doi.org/10.1016/j.jtcvs.2017.05.073
- Brodie, D., Curtis, J. R., Vincent, J.-L., Bakker, J., Brown, C. E., Creteur, J., Papazian, L., Sladen, R. N., Round Table Conf, Lorusso, R., & Ranieri, V. M. (2017). Treatment limitations in the era of ECMO. The Lancet Respiratory medicine, 5(10), 769-770. https://doi.org/10.1016/S2213-2600(17)30263-1
- Di Mauro, M., Dato, G. M. A., Barili, F., Gelsomino, S., Santse, P., Della Corte, A., Carrozza, A., Della Ratta, E., Cugola, D., Galletti, L., Devotini, R., Casabona, R., Santini, F., Salsano, A., Scrofani, R., Antona, C., Botta, L., Russo, C., Mancuso, S., ... Grp Res Outcome Cardiac Surg GIROC (2017). A predictive model for early mortality after surgical treatment of heart valve or prosthesis infective endocarditis. The EndoSCORE. International Journal of Cardiology, 241, 97-102. https://doi.org/10.1016/j.ijcard.2017.03.148
- Lorusso, R., Gelsomino, S., Parise, O., Di Mauro, M., Barili, F., Geskes, G., Vizzardi, E., Rycus, P. T., Muellenbach, R., Mueller, T., Pesenti, A., Combes, A., Peek, G., Frenckner, B., Di Nardo, M., Swol, J., Maessen, J., & Thiagarajan, R. R. (2017). Neurologic Injury in Adults Supported With Veno-Venous Extracorporeal Membrane Oxygenation for Respiratory Failure: Findings From the Extracorporeal Life Support Organization Database. Critical Care Medicine, 45(8), 1389-1397. https://doi.org/10.1097/CCM.0000000000002502
- Taccone, F. S., Malfertheiner, M. V., Ferari, F., Di Nardo, M., Swol, J., Broman, L. M., Vercaemst, L., Barrett, N., Pappalardo, F., Belohlavek, J., Mueller, T., Lorusso, R., Belliato, M., & EuroELSO Workgrp (2017). Extracorporeal CO2 removal in critically ill patients: a systematic review. Minerva Anestesiologica, 83(7), 762-772. https://doi.org/10.23736/S0375-9393.17.11835-3
- Della Corte, A., Di Mauro, M., Dato, G. A., Barili, F., Cugola, D., Gelsomino, S., Sante, P., Carozza, A., Della Ratta, E., Galletti, L., Devotini, R., Casabona, R., Santini, F., Salsano, A., Scrofani, R., Antona, C., De Vincentiis, C., Biondi, A., Beghi, C., ... Nappi, G. (2017). Surgery for prosthetic valve endocarditis: a retrospective study of a national registry. European Journal of Cardio-Thoracic Surgery, 52(1), 105-111. https://doi.org/10.1093/ejcts/ezx045
- Lorusso, R., Gelsomino, S., Parise, O., Mendiratta, P., Prodhan, P., Rycus, P., MacLaren, G., Brogan, T. V., Chen, Y.-S., Maessen, J., Hou, X., & Thiagarajan, R. R. (2017). Venoarterial Extracorporeal Membrane Oxygenation for Refractory Cardiogenic Shock in Elderly Patients: Trends in Application and Outcome From the Extracorporeal Life Support Organization (ELSO) Registry. Annals of Thoracic Surgery, 104(1), 62-69. https://doi.org/10.1016/j.athoracsur.2016.10.023
- Barili, F., Freemantle, N., Folliguet, T., Muneretto, C., De Bonis, M., Czerny, M., Obadia, J. F., Al-Attar, N., Bonaros, N., Kluin, J., Lorusso, R., Punjabi, P., Sadaba, R., Suwalskin, P., Benedetto, U., Boening, A., Falk, V., Sousa-Uva, M., Kappetein, P. A., & Menicanti, L. (2017). The flaws in the detail of an observational study on transcatheter aortic valve implantation versus surgical aortic valve replacement in intermediate-risks patients. European Journal of Cardio-Thoracic Surgery, 51(6), 1031-1035. https://doi.org/10.1093/ejcts/ezx058
- Sorokin, V., MacLaren, G., Vidanapathirana, P. C., Delnoij, T., & Lorusso, R. (2017). Choosing the appropriate configuration and cannulation strategies for extracorporeal membrane oxygenation: the potential dynamic process of organ support and importance of hybrid modes. European journal of heart failure, 19(S2), 75-83. https://doi.org/10.1002/ejhf.849
- Gelsomino, S., Lozekoot, P. W. J., de Jong, M. M. J., Luca, F., Parise, O., Matteucci, F., Romano, M., Hossien, A., La Meir, M., Marchionni, N., Maessen, J. G., & Lorusso, R. (2017). Is visceral flow during intra-aortic balloon pumping size or volume dependent?Perfusion, 32(4), 285-295. https://doi.org/10.1177/0267659116678058
- Meani, P., Gelsomino, S., Natour, E., Johnson, D. M., Rocca, H.-P. B. L., Pappalardo, F., Bidar, E., Makhoul, M., Raffa, G., Heuts, S., Lozekoot, P., Kats, S., Sluijpers, N., Schreurs, R., Delnoij, T., Montalti, A., Sels, J. W., van de Poll, M., Roekaerts, P., ... Lorusso, R. (2017). Modalities and Effects of Left Ventricle Unloading on Extracorporeal Life support: a Review of the Current Literature. European journal of heart failure, 19 Suppl 2, 84-91. https://doi.org/10.1002/ejhf.850
- Di Nardo, M., Stoppa, F., David, P., Lorusso, R., Ranieri, V. M., & Mascia, L. (2017). Reversed differential cyanosis during veno-arterial extracorporeal membrane oxygenation in infants: the reevaluation of an old phenomenon. European journal of heart failure, 19(s2), 117-119. https://doi.org/10.1002/ejhf.855
- Pappalardo, F., Montisci, A., Scandroglio, A., Belliato, M., Malfertheiner, M., Broman, M., David, P., Lorusso, R., Taccone, F., Broccati, F., & Di Nardo, M. (2017). Veno-Venous ECMO in Europe: are we all speaking the same language?Minerva Anestesiologica, 83(4), 424-425. https://doi.org/10.23736/S0375-9393.16.11766-3
- Lorusso, R. (2017). Are two crutches better than one? The ongoing dilemma on the effects and need for left ventricular unloading during veno-arterial extracorporeal membrane oxygenation. European journal of heart failure, 19(3), 413-415. https://doi.org/10.1002/ejhf.695
- Galli, D., Manuguerra, R., Monaco, R., Manotti, L., Goldoni, M., Becchi, G., Carubbi, C., Vignali, G., Cucurachi, N., Gherli, T., Nicolini, F., Lorusso, R., Vitale, M., & Corradi, D. (2017). Understanding the structural features of symptomatic calcific aortic valve stenosis: A broad-spectrum clinico-pathologic study in 236 consecutive surgical cases. International Journal of Cardiology, 228, 364-374. https://doi.org/10.1016/j.ijcard.2016.11.180
- Cuminetti, G., Gelsomino, S., Curello, S., Lorusso, R., Maessen, J. G., & Hoorntje, J. C. A. (2017). Contemporary use of arterial and venous conduits in coronary artery bypass grafting: anatomical, functional and clinical aspects. Netherlands Heart Journal, 25(1), 4-13. https://doi.org/10.1007/s12471-016-0919-2
- Lorusso, R. (2017). Predictors of survival in VA-ECMO: Whom should we cannulate?Qatar Medical Journal, 2017(1), Article 22. https://doi.org/10.5339/qmj.2017.swacelso.22
2016
- Lorusso, R., Barili, F., Di Mauro, M., Gelsomino, S., Parise, O., Rycus, P. T., Maessen, J., Mueller, T., Muellenbach, R., Belohlavek, J., Peek, G., Combes, A., Frenckner, B., Pesenti, A., & Thiagarajan, R. R. (2016). In-Hospital Neurologic Complications in Adult Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation: Results From the Extracorporeal Life Support Organization Registry. Critical Care Medicine, 44(10), e964–e972. https://doi.org/10.1097/CCM.0000000000001865
- Vizzardi, E., Maffessanti, F., Lorusso, R., Sciatti, E., Bonadei, I., Gelsomino, S., Metra, M., & Pepi, M. (2016). Ascending Aortic Dimensions in Hypertensive Subjects: Reference Values for Two-Dimensional Echocardiography. Journal of the American Society of Echocardiography, 29(9), 827-837. https://doi.org/10.1016/j.echo.2016.03.016
- Cuminetti, G., Regazzoni, V., Vizzardi, E., Bonadei, I., de Jong, M. M. J., Lorusso, R., Hoorntje, J. C. A., Gelsomino, S., & Metra, M. (2016). Cardiac ANCA-associated vasculitis mimicking an acute coronary syndrome. International Journal of Cardiology, 214, 200-201. https://doi.org/10.1016/j.ijcard.2016.03.117
- Paparella, D., Di Mauro, M., Worms, K. B., Bolotin, G., Russo, C., Trunfio, S., Scrofani, R., Antona, C., Dato, G. A., Casabona, R., Colli, A., Gerosa, G., Renzulli, A., Serraino, F., Scrascia, G., Zaccaria, S., De Bonis, M., Taramasso, M., Delgado, L., ... Miceli, A. (2016). Antiplatelet versus oral anticoagulant therapy as antithrombotic prophylaxis after mitral valve repair. Journal of Thoracic and Cardiovascular Surgery, 151(5), 1302-1308.e1. https://doi.org/10.1016/j.jtcvs.2015.12.036
- Gelsomino, S., Lozekoot, P. W. J., Lorusso, R., de Jong, M. M. J., Parise, O., Matteucci, F., Luca, F., La Meir, M., Gensini, G. F., & Maessen, J. G. (2016). Comparing short versus standard-length balloon for intra-aortic counterpulsation: results from a porcine model of myocardial ischaemia-reperfusion. European Journal of Cardio-Thoracic Surgery, 49(5), 1361-1369. https://doi.org/10.1093/ejcts/ezv401
- Swol, J., Belohlavek, J., Haft, J. W., Ichiba, S., Lorusso, R., & Peek, G. J. (2016). Conditions and procedures for in-hospital extracorporeal life support (ECLS) in cardiopulmonary resuscitation (CPR) of adult patients. Perfusion, 31(3), 182-188. https://doi.org/10.1177/0267659115591622
- Gelsomino, S., Lozekoot, P. W. J., Lorusso, R., de Jong, M. J., Parise, O., Matteucci, F., Luca, F., Kumar, N., Romano, M., Gensini, G. F., La Meir, M., & Maessen, J. G. (2016). The Optimal Weaning Strategy for Intraaortic Balloon Counterpulsation: Volume-Based Versus Rate-Based Approach in an Animal Model. Annals of Thoracic Surgery, 101(4), 1485-1493. https://doi.org/10.1016/j.athoracsur.2015.10.010
- Gelsomino, S., Lozekoot, P. W. J., Lorusso, R., de Jong, M. M. J., Parise, O., Matteucci, F., Luca, F., La Meir, M., Gensini, G. F., & Maessen, J. G. (2016). Short intra-aortic balloon pump in a swine model of myocardial ischaemia: a proof-of-concept study. European Journal of Cardio-Thoracic Surgery, 49(3), 901-909. https://doi.org/10.1093/ejcts/ezv271
- Lorusso, R., Centofanti, P., Gelsomino, S., Barili, F., Di Mauro, M., Orlando, P., Botta, L., Milazzo, F., Dato, G. A., Casabona, R., Casali, G., Musumeci, F., De Bonis, M., Zangrillo, A., Alfieri, O., Pellegrini, C., Mazzola, S., Coletti, G., Vizzardi, E., ... Russo, C. F. (2016). Venoarterial Extracorporeal Membrane Oxygenation for Acute Fulminant Myocarditis in Adult Patients: A 5-Year Multi-Institutional Experience. Annals of Thoracic Surgery, 101(3), 919-926. https://doi.org/10.1016/j.athoracsur.2015.08.014
- Beyersdorf, F., Lorusso, R., Pretre, R., & Siepe, M. (2016). The EJCTS publication family is growing: the appointment of new editors for ICVTS and MMCTS. European Journal of Cardio-Thoracic Surgery, 49(2), 361-364. https://doi.org/10.1093/ejcts/ezv461
- Beyersdorf, F., Lorusso, R., Pretre, R., & Siepe, M. (2016). The EJCTS publication family is growing: the appointment of new editors for ICVTS and MMCTS. Interactive Cardiovascular and Thoracic Surgery, 22(2), 127-130. https://doi.org/10.1093/icvts/ivw003
- Russo, C. F., Mariscalco, G., Colli, A., Sante, P., Nicolini, F., Miceli, A., De Chiara, B., Beghi, C., Gerosa, G., Glauber, M., Gherli, T., Nappi, G., Murzi, M., Molardi, A., Merlanti, B., Vizzardi, E., Bonadei, I., Coletti, G., Carrozzini, M., ... Lorusso, R. (2016). Italian multicentre study on type A acute aortic dissection: a 33-year follow-up. European Journal of Cardio-Thoracic Surgery, 49(1), 125-131. https://doi.org/10.1093/ejcts/ezv048
- Gelsomino, S., Lozekoot, P. W., Lorusso, R., de Jong, M. M., Parise, O., Matteucci, F., Luca, F., Kumar, N., Dehkord, E. S., Romano, S. M., Gensini, G. F., La Meir, M., & Maessen, J. G. (2016). A New 35-mm Short Intra-aortic Balloon Catheter A Suitable Option Also for Non-Small-Sized Patients?Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, 11(1), 46-53. https://doi.org/10.1097/IMI.0000000000000233
2015
- Gelsomino, S., Lozekoot, P., La Meir, M., Lorusso, R., Luca, F., Rostagno, C., Renzulli, A., Parise, O., Matteucci, F., Gensini, G. F., Crjins, H. J. G. M., & Maessen, J. G. (2015). Is ganglionated plexi ablation during Maze IV procedure beneficial for postoperative long-term stable sinus rhythm?International Journal of Cardiology, 192, 40-48. https://doi.org/10.1016/j.ijcard.2015.04.259
- Vizzardi, E., D'Aloia, A., Sciatti, E., Bonadei, I., Gelsomino, S., Lorusso, R., & Metra, M. (2015). Echocardiographic Evaluation of Aortic Atheromas in Patients With Aortic Stenosis. Journal of Ultrasound in Medicine, 34(1). https://doi.org/10.7863/ultra.34.1.105
- Muellenbach, R. M., Belohlavek, J., Lorusso, R., Lotz, C., & Müller, T. (2015). Monitoring of oxygen supply and demand during veno-venous extracorporeal membrane oxygenation. Intensive Care Medicine, 41(9). https://doi.org/10.1007/s00134-015-3938-3
- Martucci, V. L., Emaminia, A., del Rivero, J., Lechan, R. M., Magoon, B. T., Galia, A., Fojo, T., Leung, S., Lorusso, R., Jimenez, C., Shulkin, B. L., Audibert, J. L., Adams, K. T., Rosing, D. R., Vaidya, A., Dluhy, R. G., Horvath, K. A., & Pacak, K. (2015). Succinate dehydrogenase gene mutations in cardiac paragangliomas. American Journal of Cardiology, 115(12). https://doi.org/10.1016/j.amjcard.2015.03.020
- Saibene, A. M., Pipolo, C., Lorusso, R., Portaleone, S. M., & Felisati, G. (2015). Transnasal endoscopic microfractured fat injection in glottic insufficiency. B-ENT, 11(3).
- Vizzardi, E., Sciatti, E., Bonadei, I., Gelsomino, S., Lorusso, R., & Metra, M. (2015). To: Aortic stiffness in hypertrophic cardiomyopathy. European Review for Medical and Pharmacological Sciences, 19(3), 349-349.
2013
- Weerwind, P. W., van der Veen, F., Gelsomino, S., Nagaraj, N. G., Parise, O., Lorusso, R., Gensini, G. F., & Maessen, J. G. (2013). Cytokine removal on extracorporeal life support for treatment of acute endotoxemia: A randomized controlled animal study. International Journal of Cardiology, 168(5), 4699-4704. https://doi.org/10.1016/j.ijcard.2013.07.175
- van Garsse, L., Gelsomino, S., Luca, F., Parise, O., Lorusso, R., Cheriex, E., Caciolli, S., Vizzardi, E., Rao, C. M., Carella, R., Gensini, G. F., & Maessen, J. (2013). Left ventricular dyssynchrony is associated with recurrence of ischemic mitral regurgitation after restrictive annuloplasty. International Journal of Cardiology, 168(1), 176-184. https://doi.org/10.1016/j.ijcard.2012.09.098
- Gelsomino, S., Luca, F., Nediani, C., Orlandini, S. Z., Bani, D., Rubino, A. S., Renzulli, A., Lorusso, R., Consolo, A., Lo Cascio, A., Maessen, J., & Gensini, G. F. (2013). Early Hemodynamic and Biochemical Changes in Overloaded Swine Ventricle. Texas Heart Institute Journal, 40(3), 235-245.
- Gelsomino, S., Corradi, D., Lorusso, R., Parise, O., Callegari, S., Macchi, E., Maessen, J., & La Meir, M. (2013). Anatomical basis of minimally invasive epicardial ablation of atrial fibrillation. European Journal of Cardio-Thoracic Surgery, 43(4), 673-682. https://doi.org/10.1093/ejcts/ezs550

Overview

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Roberto Lorusso

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