• 2012
    • van Greevenbroek, M. M. J., Ghosh, S., van der Kallen, C. J. H., Brouwers, M. C. G. J., Schalkwijk, C. G., & Stehouwer, C. D. A. (2012). Up-Regulation of the Complement System in Subcutaneous Adipocytes from Nonobese, Hypertriglyceridemic Subjects Is Associated with Adipocyte Insulin Resistance. Journal of Clinical Endocrinology & Metabolism, 97(12), 4742-4752. https://doi.org/10.1210/jc.2012-2539
    • Campbell, D. J., Somaratne, J. B., Jenkins, A. J., Prior, D. L., Yii, M., Kenny, J. F., Newcomb, A. E., Schalkwijk, C. G., Black, M. J., & Kelly, D. J. (2012). Diastolic Dysfunction of Aging Is Independent of Myocardial Structure but Associated with Plasma Advanced Glycation End-Product Levels. PLOS ONE, 7(11), Article e49813. https://doi.org/10.1371/journal.pone.0049813
    • Van't Riet, E., Schram, M. T., Abbink, E. J., Admiraal, W. M., Dijk-Schaap, M. W., Holleman, F., Nijpels, G., Ozcan, B., Pijl, H., Schaper, N. C., Sijbrands, E. J. G., Silvius, B., Tack, C. J., de Valk, H. W., Wolffenbuttel, B. H. R., Stehouwer, C. D. A., & Dekker, J. M. (2012). The Diabetes Pearl: Diabetes biobanking in The Netherlands. BMC Public Health, 12(1), 949. https://doi.org/10.1186/1471-2458-12-949
    • Willemsen, S., Hartog, J. W. L., van Veldhuisen, D. J., van der Meer, P., Roze, J. F., Jaarsma, T., Schalkwijk, C., van der Horst, I. C. C., Hillege, H. L., & Voors, A. A. (2012). The role of advanced glycation end-products and their receptor on outcome in heart failure patients with preserved and reduced ejection fraction. American Heart Journal, 164(5), 742-U146. https://doi.org/10.1016/j.ahj.2012.07.027
    • Boesten, J. E. J., Kaper, J., Stoffers, H. E. J. H., Kroon, A. A., & van Schayck, O. C. P. (2012). Rimonabant improves obesity but not the overall cardiovascular risk and quality of life; results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE). Family Practice, 29(5), 521-527. https://doi.org/10.1093/fampra/cms013
    • Rosenkotter, N., van Dongen, M. C. J. M., Hellmeier, W., Simon, K., & Dagnelie, P. C. (2012). The influence of migratory background and parental education on health care utilisation of children. European Journal of Pediatrics, 171(10), 1533-1540. https://doi.org/10.1007/s00431-012-1774-9
    • Nin, J. W. M., Ferreira, I., Schalkwijk, C. G., Jorsal, A., Prins, M. H., Parving, H. .-H., Tarnow, L., Rossing, P., & Stehouwer, C. D. A. (2012). Higher plasma high-mobility group box 1 levels are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12 year follow-up study. Diabetologia, 55(9), 2489-2493. https://doi.org/10.1007/s00125-012-2622-1
    • Gruden, G., Barutta, F., Chaturvedi, N., Schalkwijk, C., Stehouwer, C. D., Pinach, S., Manzo, M., Loiacono, M., Tricarico, M., Mengozzi, G., Witte, D. R., Fuller, J. H., Perin, P. C., & Bruno, G. (2012). NH2-Terminal Probrain Natriuretic Peptide Is Associated With Diabetes Complications in the EURODIAB Prospective Complications Study. Diabetes Care, 35(9), 1931-1936. https://doi.org/10.2337/dc12-0089
    • Hanssen, N. M. J., Huijberts, M. S., Schalkwijk, C. G., Nijpels, G., Dekker, J. M., & Stehouwer, C. D. A. (2012). Associations Between the Ankle-Brachial Index and Cardiovascular and All-Cause Mortality Are Similar in Individuals Without and With Type 2 Diabetes Nineteen-year follow-up of a population-based cohort study. Diabetes Care, 35(8), 1731-1735. https://doi.org/10.2337/dc12-0178
    • Alnima, T., Scheffers, I., De Leeuw, P. W., Winkens, B., Jongen-Vancraybex, H., Tordoir, J. H. M., Schmidli, J., Mohaupt, M. G., Allemann, Y., & Kroon, A. A. (2012). Sustained acute voltage-dependent blood pressure decrease with prolonged carotid baroreflex activation in therapy-resistant hypertension. Journal of Hypertension, 30(8), 1665-1670. https://doi.org/10.1097/HJH.0b013e3283551f10
    • Rouhl, R. P. W., Damoiseaux, J. G. M. C., Lodder, J., Theunissen, R. O. M. F. I. H., Knottnerus, I. L. H., Staals, J., Henskens, L. H. G., Kroon, A. A., de Leeuw, P. W., Tervaert, J. W. C., & van Oostenbrugge, R. J. (2012). Vascular inflammation in cerebral small vessel disease. Neurobiology of Aging, 33(8), 1800-1806. https://doi.org/10.1016/j.neurobiolaging.2011.04.008
    • Alkhalaf, A., Kleefstra, N., Groenier, K. H., Bilo, H. J. G., Gans, R. O. B., Heeringa, P., Scheijen, J. L., Schalkwijk, C. G., Navis, G. J., & Bakker, S. J. L. (2012). Effect of Benfotiamine on Advanced Glycation Endproducts and Markers of Endothelial Dysfunction and Inflammation in Diabetic Nephropathy. PLOS ONE, 7(7), e40427. https://doi.org/10.1371/journal.pone.0040427
    • Ronden, R. A., Houben, A. J. H. M., Teerlink, T., Bakker, J. A., Bierau, J., Stehouwer, C. D. A., De Leeuw, P. W., & Kroon, A. A. (2012). Reduced renal plasma clearance does not explain increased plasma asymmetric dimethylarginine in hypertensive subjects with mild to moderate renal insufficiency. American Journal of Physiology-Renal Physiology, 303(1), F149-F156. https://doi.org/10.1152/ajprenal.00045.2012
    • Gruden, G., Barutta, F., Chaturvedi, N., Schalkwijk, C., Stehouwer, C. D., Witte, D. R., Fuller, J. H., Perin, P. C., & Bruno, G. (2012). Severe Hypoglycemia and Cardiovascular Disease Incidence in Type 1 Diabetes The EURODIAB Prospective Complications Study. Diabetes Care, 35(7), 1598-1604. https://doi.org/10.2337/dc11-1531
    • Hanssen, S. J. P., van de Poll, M. C. G., Houben, A. J., Vermeulen Windsant, I. C., Snoeijs, M. G., Bekers, O., Buurman, W. A., & Jacobs, M. J. H. M. (2012). Hemolysis compromises nitric oxide-dependent vasodilatory responses in patients undergoing major cardiovascular surgery.Thoracic and Cardiovascular Surgeon, 60(4), 255-261. https://doi.org/10.1055/s-0031-1299571
    • van Sloten, T. T., Pijpers, E., Stehouwer, C. D. A., & Brouwers, M. C. (2012). Metformin-associated lactic acidosis in a patient with normal kidney function.Diabetes Research and Clinical Practice, 96(3), E57-E58. https://doi.org/10.1016/j.diabres.2011.07.021
    • Brouwers, M. C. G. J., van Greevenbroek, M. M. J., Stehouwer, C. D. A., de Graaf, J., & Stalenhoef, A. F. H. (2012). The genetics of familial combined hyperlipidaemia. Nature Reviews Endocrinology, 8(6), 352-362. https://doi.org/10.1038/nrendo.2012.15
    • Simsek, S., Schalkwijk, C. G., & Wolffenbuttel, B. H. R. (2012). Effects of rosuvastatin and atorvastatin on glycaemic control in Type 2 diabetes-the CORALL study. Diabetic Medicine, 29(5), 628-631. https://doi.org/10.1111/j.1464-5491.2011.03553.x
    • Tailleux, A., Wouters, K., & Staels, B. (2012). Roles of PPARs in NAFLD: potential therapeutic targets. Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides, 1821(5), 809-18. https://doi.org/10.1016/j.bbalip.2011.10.016
    • Gerards, S. M. P. L., Dagnelie, P. C., Jansen, M. W. J., van der Goot, L. O. H. M., de Vries, N. K., Sanders, M. R., & Kremers, S. P. J. (2012). Lifestyle Triple P: a parenting intervention for childhood obesity. BMC Public Health, 12(1), Article 267. https://doi.org/10.1186/1471-2458-12-267
    • Hertle, E., van Greevenbroek, M. M. J., & Stehouwer, C. D. A. (2012). Complement C3: an emerging risk factor in cardiometabolic disease. Diabetologia, 55(4), 881-884. https://doi.org/10.1007/s00125-012-2462-z
    • Schalkwijk, C. G., & Miyata, T. (2012). Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics. Amino Acids, 42(4), 1193-1204. https://doi.org/10.1007/s00726-010-0779-9
    • Breedveld-Peters, J. J. L., Reijven, P. L. M., Wyers, C. E., van Helden, S., Arts, J. J. C., Meesters, B., Prins, M. H., van der Weijden, T., & Dagnelie, P. C. (2012). Integrated nutritional intervention in the elderly after hip fracture. A process evaluation. Clinical Nutrition, 31(2), 199-205. https://doi.org/10.1016/j.clnu.2011.10.004
    • Vaarhorst, A. A. M., Lu, Y., Heijmans, B. T., Dolle, M. E. T., Boehringer, S., Putter, H., Imholz, S., Merry, A. H. H., van Greevenbroek, M. M., Jukema, J. W., Gorgels, A. P. M., van den Brandt, P. A., Mueller, M., Schouten, L. J., Feskens, E. J. M., Boer, J. M. A., & Slagboom, P. E. (2012). Literature-Based Genetic Risk Scores for Coronary Heart Disease The Cardiovascular Registry Maastricht (CAREMA) Prospective Cohort Study. Circulation : Cardiovascular Genetics, 5(2), 202-209. https://doi.org/10.1161/CIRCGENETICS.111.960708
    • Bieghs, V., Verheyen, F., van Gorp, P. J., Hendrikx, T., Wouters, K., Lutjohann, D., Gijbels, M. J., Febbraio, M., Binder, C. J., Hofker, M. H., & Sverdlov, R. (2012). Internalization of modified lipids by cd36 and sr-a leads to hepatic inflammation and lysosomal cholesterol storage in kupffer cells. PLOS ONE, 7(3), Article e34378. https://doi.org/10.1371/journal.pone.0034378
    • Wouters, K., Cudejko, C., Gijbels, M. J. J., Fuentes, L., Bantubungi, K., Vanhoutte, J., Dievart, R., Paquet, C., Bouchaert, E., Hannou, S. A., Gizard, F., Tailleux, A., de Winther, M. P. J., Staels, B., & Paumelle, R. (2012). Bone Marrow p16(INK4a)-Deficiency Does Not Modulate Obesity, Glucose Homeostasis or Atherosclerosis Development. PLOS ONE, 7(3), e32440. https://doi.org/10.1371/journal.pone.0032440
    • Gaens, K. H. J., Niessen, P. M. G., Rensen, S. S., Buurman, W. A., Greve, J. W. M., Driessen, A., Wolfs, M. G. M., Hofker, M. H., Bloemen, J. G., Dejong, C. H., Stehouwer, C. D. A., & Schalkwijk, C. G. (2012). Endogenous formation of Nε(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis. Journal of Hepatology, 56(3), 647-655. https://doi.org/10.1016/j.jhep.2011.07.028
    • Berner, A. K., Brouwers, O., Pringle, R., Klaassen, I., Colhoun, L., McVicar, C., Brockbank, S., Curry, J. W., Miyata, T., Brownlee, M., Schlingemann, R. O., Schalkwijk, C., & Stitt, A. W. (2012). Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology. Diabetologia, 55(3), 845-854. https://doi.org/10.1007/s00125-011-2393-0
    • Van Woudenbergh, G. J., Kuijsten, A., Van der Kallen, C. J., Van Greevenbroek, M. M., Stehouwer, C. D., Blaak, E. E., & Feskens, E. J. M. (2012). Comparison of fatty acid proportions in serum cholesteryl esters among people with different glucose tolerance status: The CoDAM study. Nutrition Metabolism and Cardiovascular Diseases, 22(2), 133-140. https://doi.org/10.1016/j.numecd.2010.05.008
    • Hustad, S., Eussen, S., Midttun, O., Ulvik, A., van de Kant, P. M., Morkrid, L., Gislefoss, R., & Ueland, P. M. (2012). Kinetic Modeling of Storage Effects on Biomarkers Related to B Vitamin Status and One-Carbon Metabolism. Clinical Chemistry, 58(2), 402-410. https://doi.org/10.1373/clinchem.2011.174490
    • Gilsing, A. M. J., Weijenberg, M. P., Hughes, L. A. E., Ambergen, T., Dagnelie, P. C., Goldbohm, R. A., van den Brandt, P. A., & Schouten, L. J. (2012). Longitudinal Changes in BMI in Older Adults Are Associated with Meat Consumption Differentially, by Type of Meat Consumed. Journal of Nutrition, 142(2), 340-349. https://doi.org/10.3945/jn.111.146258
    • Nin, J. W. M., Ferreira, I., Schalkwijk, C. G., Prins, M. H., Chaturvedi, N., Fuller, J. H., & Stehouwer, C. D. A. (2012). Serum high-mobility group box-1 levels are positively associated with micro- and macroalbuminuria but not with cardiovascular disease in type 1 diabetes: the EURODIAB Prospective Complications Study. European Journal of Endocrinology, 166(2), 325-332. https://doi.org/10.1530/EJE-11-0662
    • Bieghs, V., van Gorp, P. J., Wouters, K., Hendrikx, T., Gijbels, M. J., van Bilsen, M., de Bakker, J., Binder, C. J., Lutjohann, D., Staels, B., Hofker, M. H., & Sverdlov, R. (2012). LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease. PLOS ONE, 7(1), Article e30668. https://doi.org/10.1371/journal.pone.0030668
    • Arts, I. C. W., Coolen, E., Bours, M. J. L., Huyghebaert, N., Stuart, M. A. C., Bast, A., & Dagnelie, P. C. (2012). Adenosine 5' -triphosphate (ATP) supplements are not orally bioavailable: a randomized, placebocontrolled cross-over trial in healthy humans. Journal of the International Society of Sports Nutrition, 9(1), 16. https://doi.org/10.1186/1550-2783-9-16
    • Breedveld-Peters, J. J. L., Reijven, P. L. M., Wyers, C. E., Hendrikx, A. A., Verburg, A. D., Schols, J. M. G. A., Prins, M. H., van der Weijden, T. D., & Dagnelie, P. C. (2012). Barriers and facilitators of nutritional intervention after hip fracture in integrated care as perceived by the different health care professionals: a qualitative interview study. e - SPEN Journal: the European e-journal of clinical nutrition and metabolism, 7(5), e182-e188. https://doi.org/10.1016/J.CLNME.2012.07.001
    • Gerards, S., Dagnelie, P. C., Jansen, M. W. J., de Vries, N. K., & Kremers, S. P. J. (2012). Barriers to successful recruitment of parents of overweight children for an obesity prevention intervention: a qualitative study among youth health care professionals. BMC Family Practice, 13, 37. https://doi.org/10.1186/1471-2296-13-37
    • van Onzenoort, H. A. W., Verberk, W. J., Kroon, A. A., Kessels, A. G. H., Neef, C., van der Kuy, P. H. M., & de Leeuw, P. W. (2012). Electronic monitoring of adherence, treatment of hypertension, and blood pressure control. American Journal of Hypertension, 25(1), 54-59. https://doi.org/10.1038/ajh.2011.153
    • Touwslager, R. N., Houben, A. J., Gielen, M. J. F., Zeegers, M. P. A., Stehouwer, C. D. A., Zimmermann, L. J. I., Kessels, A. G., Gerver, W. J. M., Blanco, C. E., & Mulder, A. L. M. (2012). Endothelial vasodilatation in newborns is related to body size and maternal hypertension.Journal of Hypertension, 30(1), 124-131. https://doi.org/10.1097/HJH.0b013e32834d75c6
    • van Greevenbroek, M. M. J., Jacobs, M., van der Kallen, C. J. H., Blaak, E. E., Jansen, E., Schalkwijk, C. G., Feskens, E. J. M., & Stehouwer, C. D. A. (2012). Human plasma complement C3 is independently associated with coronary heart disease, but only in heavy smokers (the CODAM study). International Journal of Cardiology, 154(2), 158-162. https://doi.org/10.1016/j.ijcard.2010.09.017
    • Touwslager, R. N. H., Gerver, W. J. M., Tan, F. E. S., Gielen, M., Zeegers, M. P., Zimmermann, L. J., Houben, A. J. H. M., Blanco, C. E., Stehouwer, C. D. A., & Mulder, A. L. M. (2012). Influence of Growth During Infancy on Endothelium-Dependent Vasodilatation at the Age of 6 Months. Hypertension, 60(5), 1294-1300. https://doi.org/10.1161/HYPERTENSIONAHA.112.199125
    • Scheijen, J. L. J. M., Hanssen, N. M., van de Waarenburg, M. P., Jonkers, D. M. A. E., Stehouwer, C. D. A., & Schalkwijk, C. G. (2012). L(+) and d(-) lactate are increased in plasma and urine samples of type 2 diabetes as measured by a simultaneous quantification of l(+) and d(-) lactate by reversed-phase liquid chromatography tandem mass spectrometry. Experimental Diabetes Research, 2012, Article 234812. https://doi.org/10.1155/2012/234812
    • van Bussel, B. C. T., Henry, R. M., Schalkwijk, C. G., Dekker, J. M., Nijpels, G., & Stehouwer, C. D. A. (2012). Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: the Hoorn Study. Journal of Hypertension, 30(4), 744-752. https://doi.org/10.1097/HJH.0b013e328350a487
    • Schiefer, M., Aquarius, M., Leffers, P., Stassen, P., van Deursen, C., Oostenbrug, L., Jansen, L., Masclee, A., & Keulemans, Y. C. (2012). Predictive validity of the Glasgow Blatchford Bleeding Score in an unselected emergency department population in continental Europe. European Journal of Gastroenterology & Hepatology, 24(4), 382-387. https://doi.org/10.1097/MEG.0b013e3283505965
    • Witteman, B. P. L., Strijkers, R., de Vries, E. E., Toemen, L., Conchillo, J. M., Hameeteman, W., Dagnelie, P. C., Koek, G. H., & Bouvy, N. D. (2012). Transoral incisionless fundoplication for treatment of gastroesophageal reflux disease in clinical practice.Surgical endoscopy and other interventional techniques, 26(11), 3307-3315. https://doi.org/10.1007/s00464-012-2324-2
    • Rouhl, R. P. W., Mertens, A. E. C. S., van Oostenbrugge, R. J., Damoiseaux, J. G. M. C., Debrus-Palmans, L. L., Henskens, L. H. G., Kroon, A. A., de Leeuw, P. W., Lodder, J., & Tervaert, J. W. C. (2012). Angiogenic T-Cells and Putative Endothelial Progenitor Cells in Hypertension-Related Cerebral Small Vessel Disease. Stroke, 43(1), 256-U509. https://doi.org/10.1161/STROKEAHA.111.632208
    • Krijnen, P. A. J., Hahn, N. E., Kholova, I., Baylan, U., Sipkens, J. A., van Alphen, F. P., Vonk, A. B. A., Simsek, S., Meischl, C., Schalkwijk, C. G., van Buul, J. D., van Hinsbergh, V. W. M., & Niessen, H. W. M. (2012). Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients. Basic Research in Cardiology, 107(1), 233. https://doi.org/10.1007/s00395-011-0233-5
    • Wlazlo, N., van Greevenbroek, M. M. J., Ferreira, I., Bravenboer, B., & Stehouwer, C. D. A. (2012). The diagnosis of non-alcoholic fatty liver disease. Alimentary Pharmacology & Therapeutics, 35(1), 204-205. https://doi.org/10.1111/j.1365-2036.2011.04909.x
    • Hoppe, U. C., Brandt, M.-C., Wachter, R., Beige, J., Rump, L. C., Kroon, A. A., Cates, A. W., Lovett, E. G., & Haller, H. (2012). Minimally invasive system for baroreflex activation therapy chronically lowers blood pressure with pacemaker-like safety profile: results from the Barostim neo trial. Journal of the American Society of Hypertension, 6(4), 270-276. https://doi.org/10.1016/j.jash.2012.04.004
    • le Poole, C. Y., van Ittersum, F. J., Valentijn, R. M., Teerlink, T., Lindholm, B., Ter Wee, P. M., & Schalkwijk, C. G. (2012). "NEPP" PERITONEAL DIALYSIS REGIMEN HAS BENEFICIAL EFFECTS ON PLASMA CEL AND 3-DG, BUT NOT PENTOSIDINE, CML, AND MGO. Peritoneal Dialysis International, 32(1), 45-54. https://doi.org/10.3747/pdi.2010.00101