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van Bussel, B. C. T., van de Poll, M. C. G., Schalkwijk, C. G., & Bergmans, D. C. J. J. (2017). Increased Dicarbonyl Stress as a Novel Mechanism of Multi-Organ Failure in Critical Illness. International journal of molecular sciences, 18(2), Article 346. https://doi.org/10.3390/ijms18020346

De Clerck, E. E. B., Schouten, J. S. A. G., Berendschot, T. T. J. M., Beckers, H. J. M., Schaper, N. C., Schram, M. T., Stehouwer, C. D. A., & Webers, C. A. B. (2017). Loss of Temporal Peripapillary Retinal Nerve Fibers in Prediabetes or Type 2 Diabetes Without Diabetic Retinopathy: The Maastricht Study. Investigative Ophthalmology & Visual Science, 58(2), 1017-1027. https://doi.org/10.1167/iovs.16-19638

Barutta, F., Bruno, G., Matullo, G., Chaturvedi, N., Grimaldi, S., Schalkwijk, C., Stehouwer, C. D., Fuller, J. H., & Gruden, G. (2017). MicroRNA-126 and micro-/macrovascular complications of type 1 diabetes in the EURODIAB Prospective Complications Study. Acta Diabetologica, 54(2), 133-139. https://doi.org/10.1007/s00592-016-0915-4

van Iterson, M., van Zwet, E. W., Heijmans, B. T., 't Hoen, P. A. C., van Meurs, J., Jansen, R., Franke, L., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., van Greevenbroek, M. M. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, S., Tigchelaar, E. F., Eline Slagboom, P., ... BIOS Consortium (2017). Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution. Genome Biology, 18(1), Article 19. https://doi.org/10.1186/s13059-016-1131-9

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Joosen, D. A. W. A., Zwietering, N. A., Bosch, M., & Stassen, P. M. (2017). Characteristics and outcome of acute medical admissions with hyponatremia: Even mild hyponatremia is associated with higher mortality. Acute Medicine, 16(4), 156-163. https://doi.org/10.52964/AMJA.0677

van Twist, D. J. L., van de laar, R. J. J. M., Brans, R. J. B., Refos, J. W. J., & Kroon, A. A. (2017). A 34-year-old man with back pain. Netherlands Journal of Medicine, 75(1), 45-46. http://www.njmonline.nl/article_ft.php?a=1809&d=1199&i=202

van Dooren, F. E. P., Pouwer, F., Schalkwijk, C. G., Sep, S. J. S., Stehouwer, C. D. A., Henry, R. M. A., Dagnelie, P. C., Schaper, N. C., van der Kallen, C. J. H., Koster, A., Denollet, J., Verhey, F. R. J., & Schram, M. T. (2017). Advanced Glycation End Product (AGE) Accumulation in the Skin is Associated with Depression: The Maastricht Study. Depression and Anxiety, 34(1), 59-67. https://doi.org/10.1002/da.22527

van Varik, B. J., Vossen, L. M., Rennenberg, R. J., Stoffers, H. E., Kessels, A. G., de Leeuw, P. W., & Kroon, A. A. (2017). Arterial stiffness and decline of renal function in a primary care population. Hypertension Research, 40(1), 73-78. https://doi.org/10.1038/hr.2016.113

Joris, P. J., Plat, J., Kusters, Y. H. A. M., Houben, A. J. H. M., Stehouwer, C. D. A., Schalkwijk, C. G., & Mensink, R. P. (2017). Diet-induced weight loss improves not only cardiometabolic risk markers but also markers of vascular function: a randomized controlled trial in abdominally obese men. American Journal of Clinical Nutrition, 105(1), 23-31. https://doi.org/10.3945/ajcn.116.143552

Bonder, M. J., Luijk, R., Zhernakova, D. V., Moed, M., Deelen, P., Vermaat, M., van Iterson, M., van Dijk, F., van Galen, M., Bot, J., Slieker, R. C., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Arindrarto, W., ... Franke, L. (2017). Disease variants alter transcription factor levels and methylation of their binding sites. Nature Genetics, 49(1), 131-138. https://doi.org/10.1038/ng.3721

Zhernakova, D. V., Deelen, P., Vermaat, M., van Iterson, M., van Galen, M., Arindrarto, W., van 't Hof, P., Mei, H., van Dijk, F., Westra, H.-J., Bonder, M. J., van Rooij, J., Verkerk, M., Jhamai, P. M., Moed, M., Kielbasa, S. M., Bot, J., Nooren, I., Pool, R., ... Franke, L. (2017). Identification of context-dependent expression quantitative trait loci in whole blood. Nature Genetics, 49(1), 139-145. https://doi.org/10.1038/ng.3737

van den Nouland, D. P. A., Brouwers, M. C. G. J., & Stassen, P. M. (2017). Prognostic value of plasma lactate levels in a retrospective cohort presenting at a university hospital emergency department. BMJ Open, 7(1), Article 011450. https://doi.org/10.1136/bmjopen-2016-011450

Pearce, K., Hatzinikolas, A., Moran, L., de Courten, M. P. J., Forbes, J., Scheijen, J. L. J. M., Schalkwijk, C. G., Walker, K., & de Courten, B. (2017). Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity. International Journal of Food Sciences and Nutrition, 68(8), 1021-1026. https://doi.org/10.1080/09637486.2017.1319468

Mitsides, N., Cornelis, T., Broers, N. J. H., Diederen, N. M. P., Brenchley, P., Heitink-ter Braak, N., van der Sande, F. M., Schalkwijk, C. G., Kooman, J. P., & Mitra, S. (2017). Inflammatory and Angiogenic Factors Linked to Longitudinal Microvascular Changes in Hemodialysis Patients Irrespective of Treatment Dose Intensity. Kidney & Blood Pressure Research, 43(5), 905-918. https://doi.org/10.1159/000485048

Dalem, J. V., Brouwers, M. C. G. J., Stehouwer, C. D. A., Krings, A., Leufkens, H. G. M., Driessen, J. H. M., Devries, F., & Burden, A. M. (2016). Het risico op hypoglykemieen bij sulfonylureum- derivaten ten opzichte van metformine in relatie tot nierfunctie en metabolietgroep. Pharmaceutisch Weekblad, 151(50), 37-41.

Uiterwijk, R., van Oostenbrugge, R. J., Huijts, M., De Leeuw, P. W., Kroon, A. A., & Staals, J. (2016). Total Cerebral Small Vessel Disease MRI Score Is Associated with Cognitive Decline in Executive Function in Patients with Hypertension. Frontiers in Aging Neuroscience, 8(DEC), Article 301. https://doi.org/10.3389/fnagi.2016.00301

Ras, R. T., Fuchs, D., Koppenol, W. P., Schalkwijk, C. G., Otten-Hofman, A., Garczarek, U., Greyling, A., Wagner, F., & Trautwein, E. A. (2016). Effect of a plant sterol-enriched spread on biomarkers of endothelial dysfunction and low-grade inflammation in hypercholesterolaemic subjects. Journal of Nutritional Science, 5, Article e44. https://doi.org/10.1017/jns.2016.40

Reynaert, N. L., Gopal, P., Rutten, E. P. A., Wouters, E. F. M., & Schalkwijk, C. G. (2016). Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease. International Journal of Biochemistry & Cell Biology, 81(Part B), 403-418. https://doi.org/10.1016/j.biocel.2016.06.016

Martens, R. J. H., Henry, R. M. A., Houben, A. J. H. M., van der Kallen, C. J. H., Kroon, A. A., Schalkwijk, C. G., Schram, M. T., Sep, S. J. S., Schaper, N. C., Dagnelie, P. C., Muris, D. M. J., Gronenschild, E. H. B. M., van der Sande, F. M., Leunissen, K. M. L., Kooman, J. P., & Stehouwer, C. D. A. (2016). Capillary Rarefaction Associates with Albuminuria: The Maastricht Study. Journal of the American Society of Nephrology, 27(12), 3748-3757. https://doi.org/10.1681/ASN.2015111219

Jansen, J., van Bussel, F. C. G., van de Haar, H. J., van Osch, M. J. P., Hofman, P. A. M., van Boxtel, M. P. J., van Oostenbrugge, R. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Backes, W. H. (2016). Cerebral blood flow, blood supply, and cognition in Type 2 Diabetes Mellitus. Scientific Reports, 6(1), Article 10. https://doi.org/10.1038/s41598-016-0003-6

Spauwen, P. J. J., Martens, R., Stehouwer, C. D. A., Verhey, F. R. J., Schram, M. T., Sep, S. J. S., van der Kallen, C. J. H., Dagnelie, P. C., Henry, R. M. A., Schaper, N. C., & van Boxtel, M. P. J. (2016). Lower verbal intelligence is associated with diabetic complications and slower walking speed in people with Type 2 diabetes: the Maastricht Study. Diabetic Medicine, 33(12), 1632–1639. https://doi.org/10.1111/dme.13105

Begieneman, M. P. V., Emmens, R. W., Rijvers, L., Woudstra, L., Paulus, W. J., Kubat, B., Vonk, A. B. A., van Rossum, A. C., Wouters, D., Zeerleder, S., van Ham, M., Schalkwijk, C. G., Niessen, H. W. M., & Krijnen, P. A. J. (2016). Myocardial infarction induces atrial inflammation that can be prevented by C1-esterase inhibitor. Journal of Clinical Pathology, 69(12), 1093-1099. https://doi.org/10.1136/jclinpath-2016-203639

Fokkens, B. T., Mulder, D. J., Nugteren, M. B., Schalkwijk, C. G., Scheijen, J. L., Smit, A. J., & Los, L. I. (2016). Surface Area of Detachment, Proliferative Vitreoretinopathy, and Pulse Pressure, but not AGEs, are Associated With Retinal Redetachment. Investigative Ophthalmology & Visual Science, 57(15), 6633-6638. https://doi.org/10.1167/iovs.16-20735

Sörensen, B., Houben, B., Berendschot, T. T. J. M., Schouten, J. S. A. G., Kroon, A. A., van der Kallen, C. J. H., Henry, R. M. A., Koster, A., Sep, S. J. S., Dagnelie, P. C., Schaper, N. C., Schram, M. T., & Stehouwer, C. D. A. (2016). Prediabetes and Type 2 Diabetes Are Associated With Generalized Microvascular Dysfunction The Maastricht Study. Circulation, 134(18), 1339-1352. https://doi.org/10.1161/CIRCULATIONAHA.116.023446

Nielen, J. T. H., Dagnelie, P. C., Emans, P., Veldhorst-Janssen, N., Lalmohamed, A., van Staa, T.-P., Boonen, A., van den Bemt, B., & de Vries, F. (2016). Safety and efficacy of new oral anticoagulants and low-molecular-weight heparins compared with aspirin in patients undergoing total knee and hip replacements. Pharmacoepidemiology and Drug Safety, 25(11), 1245-1252. https://doi.org/10.1002/pds.4089

Schutten, M. T. J., Houben, A. J. H. M., Kroon, A. A., Stehouwer, C. D. A., & de Leeuw, P. W. (2016). Aldosterone-Renin Ratio and Side-Selective Renal Perfusion in Essential Hypertension. American Journal of Hypertension, 29(11), 1311-1316. https://doi.org/10.1093/ajh/hpw077

Grassi, D., Draijer, R., Schalkwijk, C., Desideri, G., D'Angeli, A., Francavilla, S., Mulder, T., & Ferri, C. (2016). Black Tea Increases Circulating Endothelial Progenitor Cells and Improves Flow Mediated Dilatation Counteracting Deleterious Effects from a Fat Load in Hypertensive Patients: A Randomized Controlled Study. Nutrients, 8(11), Article UNSP 727. https://doi.org/10.3390/nu8110727

de Waard, E. A. C., Koster, A., Melai, T., van Geel, T. A., Henry, R. M. A., Schram, M. T., Dagnelie, P. C., van der Kallen, C. J., Sep, S. J. S., Stehouwer, C. D. A., Schaper, N. C., Köhler, S., Savelberg, H. H. C. M., Geusens, P. P. M. M., & van den Bergh, J. P. W. (2016). The association between glucose metabolism status, diabetes severity and a history of fractures and recent falls in participants of 50 years and older-the Maastricht Study. Osteoporosis International, 27(11), 3207-3216. https://doi.org/10.1007/s00198-016-3645-0

Janssen, E. P. C. J., Köhler, S., Stehouwer, C. D. A., Schaper, N. C., Dagnelie, P. C., Sep, S. J. S., Henry, R. M. A., van der Kallen, C. J. H., Verhey, F. R., & Schram, M. T. (2016). The Patient Health Questionnaire-9 as a Screening Tool for Depression in Individuals with Type 2 Diabetes Mellitus: The Maastricht Study. Journal of the American Geriatrics Society, 64(11), E201-E206. https://doi.org/10.1111/jgs.14388

Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Turtoi, A., Costanza, B., Smargiasso, N., Baiwir, D., Scheijen, J. L., Schalkwijk, C. G., Leenders, J., De Tullio, P., Bianchi, E., Thiry, M., Uchida, K., Spiegel, D. A., Cochrane, J. R., ... Bellahcene, A. (2016). Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis. Elife, 5(OCTOBER2016), Article e19375. https://doi.org/10.7554/elife.19375

Marsch, E., Demandt, J. A. F., Theelen, T. L., Tullemans, B. M. E., Wouters, K., Boon, M. R., van Dijk, T. H., Gijbels, M. J., Dubois, L. J., Meex, S. J. R., Mazzone, M., Hung, G., Fisher, E. A., Biessen, E. A. L., Daemen, M. J. A. P., Rensen, P. C. N., Carmeliet, P., Groen, A. K., & Sluimer, J. C. (2016). Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia. European Heart Journal, 37(39), 2993-2997. https://doi.org/10.1093/eurheartj/ehw156

Simons, N., Dekker, J. M., van Greevenbroek, M. M. J., Nijpels, G., 't Hart, L. M., van der Kallen, C. J. H., Schalkwijk, C. G., Schaper, N. C., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2016). A Common Gene Variant in Glucokinase Regulatory Protein Interacts With Glucose Metabolism on Diabetic Dyslipidemia: the Combined CODAM and Hoorn Studies. Diabetes Care, 39(10), 1811-1817. https://doi.org/10.2337/dc16-0153

Geijselaers, S. L. C., Sep, S. J. S., Schram, M. T., van Boxtel, M. P. J., van Sloten, T. T., Henry, R. M. A., Reesink, K. D., Kroon, A. A., Koster, A., Schaper, N. C., Dagnelie, P. C., van der Kallen, C. J. H., Biessels, G. J., & Stehouwer, C. D. A. (2016). Carotid stiffness is associated with impairment of cognitive performance in individuals with and without type 2 diabetes. The Maastricht Study. Atherosclerosis, 253, 186-193. https://doi.org/10.1016/j.atherosclerosis.2016.07.912

Mommersteeg, P. M. C., Schoemaker, R. G., Naude, P. J. W., Eisel, U. L. M., Garrelds, I. M., Schalkwijk, C. G., Westerhuis, B. W. J. J. M., Kop, W. J., & Denollet, J. (2016). Depression and markers of inflammation as predictors of all-cause mortality in heart failure. Brain Behavior and Immunity, 57, 144-150. https://doi.org/10.1016/j.bbi.2016.03.012

Magdelijns, F. J. H., van Avesaath, R. E. M., Pijpers, E., Stehouwer, C. D. A., & Stassen, P. M. (2016). Health-care-related adverse events leading to admission in older individuals: incidence, predictive factors and consequences. European Journal of Public Health, 26(5), 743-748. https://doi.org/10.1093/eurpub/ckw021

van der Berg, J. D., Willems, P., van der Velde, J. H., Savelberg, H. H., Schaper, N. C., Schram, M. T., Sep, S., Dagnelie, P. C., Bosma, H., Stehouwer, C. D., & Koster, A. (2016). Identifying waking time in 24-h accelerometry data in adults using an automated algorithm. Journal of Sports Sciences, 34(19), 1867-1873. https://doi.org/10.1080/02640414.2016.1140908

Hrolfsdottir, L., Schalkwijk, C. G., Birgisdottir, B. E., Gunnarsdottir, I., Maslova, E., Granstrom, C., Strom, M., Olsen, S. F., & Halldorsson, T. I. (2016). Maternal Diet, Gestational Weight Gain, and Inflammatory Markers During Pregnancy. Obesity, 24(10), 2133-2139. https://doi.org/10.1002/oby.21617

van Eupen, M. G. A., Schram, M. T., van Sloten, T. T., Scheijen, J., Sep, S. J. S., van der Kallen, C. J., Dagnelie, P. C., Koster, A., Schaper, N., Henry, R. M. A., Kroon, A. A., Smit, A. J., Stehouwer, C. D. A., & Schalkwijk, C. G. (2016). Skin Autofluorescence and Pentosidine Are Associated With Aortic Stiffening: The Maastricht Study. Hypertension, 68(4), 956-963. https://doi.org/10.1161/HYPERTENSIONAHA.116.07446

Slieker, R. C., van Iterson, M., Luijk, R., Beekman, M., Zhernakova, D. V., Moed, M. H., Mei, H., van Galen, M., Deelen, P., Bonder, M. J., Zhernakova, A., Uitterlinden, A. G., Tigchelaar, E. F., Stehouwer, C. D. A., Schalkwijk, C. G., van der Kallen, C. J. H., Hofman, A., van Heemst, D., de Geus, E. J., ... Heijmans, B. T. (2016). Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms. Genome Biology (Online), 17(1), Article 191. https://doi.org/10.1186/s13059-016-1053-6

Magdelijns, F. J. H., Schepers, L., Pijpers, E., Stehouwer, C. D. A., & Stassen, P. M. (2016). Unplanned readmissions in younger and older adult patients: the role of healthcare-related adverse events. European Journal of Medical Research, 21(1), Article 35. https://doi.org/10.1186/s40001-016-0230-0

Sluik, D., Geelen, A., de Vries, J. H. M., Eussen, S. J. P. M., Brants, H. A. M., Meijboom, S., van Dongen, M., Bueno-de-Mesquita, H. B., Wijckmans-Duysens, N. E. G., van ' t Veer, P., Dagnelie, P. C., Ocke, M. C., & Feskens, E. J. M. (2016). A national FFQ for the Netherlands (the FFQ-NL 1.0): validation of a comprehensive FFQ for adults. British Journal of Nutrition, 116(5), 913-923. https://doi.org/10.1017/S0007114516002749

Maessen, D. E., Hanssen, N. M., Lips, M. A., Scheijen, J. L., van Dijk, K. W., Pijl, H., Stehouwer, C. D., & Schalkwijk, C. G. (2016). Energy restriction and Roux-en-Y gastric bypass reduce postprandial alpha-dicarbonyl stress in obese women with type 2 diabetes. Diabetologia, 59(9), 2013-2017. https://doi.org/10.1007/s00125-016-4009-1

van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., Puts, N. A. J., Edden, R. A. E., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. (2016). Increased GABA concentrations in type 2 diabetes mellitus are related to lower cognitive functioning. Medicine, 95(36), Article e4803. https://doi.org/10.1097/MD.0000000000004803

Montero, D., Houben, B., Koster, A., Muris, D. M. J., Schram, M. T., Gronenschild, E. H., Sep, S. J. S., Henry, R. M. A., van der Kallen, C. J. H., Schaper, N. C., Dagnelie, P. C., van Geel, T. A. C. M., Kremers, S. P. J., Savelberg, H. H. C. M., & Stehouwer, C. D. A. (2016). Physical Activity Is Associated With Glucose Tolerance Independent of Microvascular Function: The Maastricht Study. Journal of Clinical Endocrinology & Metabolism, 101(9), 3324-3332. https://doi.org/10.1210/jc.2016-1526

Meertens, J. H., Nienhuis, H. L., Lefrandt, J. D., Schalkwijk, C. G., Nyyssonen, K., Ligtenberg, J. J. M., Smit, A. J., Zijlstra, J. G., & Mulder, D. J. (2016). The Course of Skin and Serum Biomarkers of Advanced Glycation Endproducts and Its Association with Oxidative Stress, Inflammation, Disease Severity, and Mortality during ICU Admission in Critically Ill Patients: Results from a Prospective Pilot Study. PLOS ONE, 11(8), Article e0160893. https://doi.org/10.1371/journal.pone.0160893

van Twist, D. J. L., Houben, A. J. H. M., de Leeuw, P. W., & Kroon, A. A. (2016). Acute eprosartan-induced intrarenal vasodilation in hypertensive humans is not influenced by dietary sodium intake or angiotensin II co-infusion. Journal of Hypertension, 34(8), 1607-1614. https://doi.org/10.1097/HJH.0000000000000974

van Dooren, F. E. P., Schram, M. T., Schalkwijk, C. G., Stehouwer, C. D. A., Henry, R. M. A., Dagnelie, P. C., Schaper, N. C., van der Kallen, C. J. H., Koster, A., Sep, S. J. S., Denollet, J., Verhey, F. R. J., & Pouwer, F. (2016). Associations of low grade inflammation and endothelial dysfunction with depression - The Maastricht Study. Brain Behavior and Immunity, 56, 390-396. https://doi.org/10.1016/j.bbi.2016.03.004