Section Martijn Brouwers
- 2026
- Yu, E. Y. W., Ren, H. Y., Liang, X., Xi, Y., Shuai, M., Miao, Z., Xu, F., Zhang, K., Shen, L., Xia, H., Schram, M. T., van Greevenbroek, M., de Galan, B. E., van der Kallen, C. J. H., Linden, D. E. J., Blokland, G. A. M., Arts, I. C. W., Berendschot, T. T. J. M., Yan, Y., ... Zheng, J. S. (2026). Trans-ethnic estimation and implications of genetic impact on continuous glycemic profiles. Cell Discovery, 12(1), Article 40. https://doi.org/10.1038/s41421-026-00897-2
- Mirjalili, F., Jambarsang, S., Farashahi-Yazd, E., Dianati, M., Eussen, S. J. P. M., Schram, M. T., Koster, A., Salehi-Abargouei, A., Yi-Wen Yu, E., Zeegers, M. P., & Wesselius, A. (2026). Adherence to empirically derived dietary patterns and risk of depression symptoms and anxiety disorder: The Maastricht Cohort Study. American Journal of Clinical Nutrition, 124(3), Article 101415. https://doi.org/10.1016/j.ajcnut.2026.101415
- Lintsen, D., Schuetz, L., Lins, P. P., Bronckaers, A., Verboven, K., Wouters, K., & Broux, B. (2026). Adipose tissue-derived extracellular vesicles as drivers of endothelial dysfunction in obesity. Trends in Endocrinology and Metabolism, 37(8), 789-801. https://doi.org/10.1016/j.tem.2026.01.006
- Sezer, B., Albers, J., Meisters, R., Schram, M. T., de Galan, B. E., van der Kallen, C., van Greevenbroek, M., Dagnelie, P., Koster, A., & Bosma, H. (2026). Exploring the role of class stigma in socioeconomic inequalities in type 2 diabetes: The Maastricht Study. Journal of Health Psychology, 31(9), 3578-3588. https://doi.org/10.1177/13591053251395856
- Tore, E. C., Briones, A. M., Bruno, R. M., Dalli, J., Eussen, S. J. P. M., Schalkwijk, C. G., & van Greevenbroek, M. M. J. (2026). Plasma-based low-grade inflammation and endothelial dysfunction explain a small but significant proportion of the association between the n-3 polyunsaturated fatty acids and cardiovascular diseases: The Maastricht Study. Journal of Clinical Lipidology, 20(7), 1352-1366. https://doi.org/10.1016/j.jacl.2026.05.228
- Holthuijsen, D. D. B., Rijnhart, J. J. M., van Roekel, E. H., Bours, M. J. L., Ueland, P. M., Breukink, S. O., Janssen-heijnen, M. L. G., Konsten, J. L., Keulen, E. T. P., McCann, A., Brezina, S., Gigic, B., Ose, J., Weijenberg, M. P., & Eussen, S. J. P. M. (2026). The mediating role of the kynurenine pathway in longitudinal associations between dietary intake and quality of life in colorectal cancer survivors up to 12 months posttreatment. International Journal of Cancer, 159(1), 122-143. https://doi.org/10.1002/ijc.70363
- Valente, M. J., Cao, B., Holthuijsen, D. D. B., Bours, M. J. L., Eussen, S. J. P. M., Weijenberg, M. P., & Rijnhart, J. J. M. (2026). Response to “Ratios are misleading exposure variables that compromise a regression model unless fundamental scaling assumptions are satisfied: a comment on Valente et al.”. Journal of Clinical Epidemiology, 195, Article 112257. https://doi.org/10.1016/j.jclinepi.2026.112257
- Claassen, L., Baars, V. M. E. P., Cals, J. W. L., Stassen, P. M., & Latten, G. H. P. (2026). Patient-Physician Agreement on Diagnosis in the ED, Part of Diagnostic Excellence. A Prospective Multicenter Study. Academic Emergency Medicine, 33(6), Article e70365. https://doi.org/10.1111/acem.70365
- Daemen, S., Adelaar, T. I., Barlampas, P., Zhang, X., Schalkwijk, C. G., & Wouters, K. (2026). Managing Autofluorescence in Spectral Flow Cytometry for Macrophage Identification in the Liver. European Journal of Immunology, 56(6), Article e70217. https://doi.org/10.1002/eji.70217
- Choe, K., Bakker, L., van den Hove, D. L. A., Eussen, S. J. P. M., Kenis, G., Ramakers, I. H. G. B., Verhey, F. R. J., Rutten, B. P. F., & Kohler, S. (2026). Kynurenine pathway dysregulation in cognitive impairment and dementia: a systematic review and meta-analysis. Geroscience, 48(3), 4585-4619. Article 120819. https://doi.org/10.1007/s11357-025-01636-3
- Arts, J., Kremers, S. P. J., Mommers, M., Eussen, S. J. M. P., & Gubbels, J. S. (2026). Associations of food parenting practices in early childhood with dietary intake, BMI, and weight status in young adulthood: the KOALA Birth Cohort Study. Nutrition Journal, 25(1), Article 72. https://doi.org/10.1186/s12937-026-01331-9
- Okoro, C., Zhou, T. L., van der Kallen, C. J. H., Koster, A., Sutedja, N. A., Berendschot, T. T. J. M., de Galan, B. E., Eussen, S. J. P. M., Schram, M. T., & Kroon, A. A. (2026). Association of type 2 diabetes according to the number of cardiovascular risk factors within the recommended range with neuropathy - The Maastricht Study. Diabetes Research and Clinical Practice, 235, Article 113212. https://doi.org/10.1016/j.diabres.2026.113212
- Buziau, A. M., Wesselius, A., Yu, E. Y.-W., Korver-Keularts, I. M. L. W., Visser, D., Steinbusch, L. K. M., Simons, P. I. H. G., van Greevenbroek, M. M. J., Dagnelie, P. C., Kooi, M. E., Eussen, S. J. P. M., Arts, I. C. W., van der Kallen, C. J. H., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2026). Metabolite Erythritol in 24-Hour Urine Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study. Diabetes, 75(5), 762-771. https://doi.org/10.2337/db25-0881
- Yu, Y., Berendschot, T. T. J. M., Eussen, S. J. P. M., van der Kallen, C. J. H., Webers, C. A. B., & Ramdas, W. D. (2026). The Association Between Adherence to the Dutch Healthy Diet Index and Glaucoma Prevalence-The Maastricht Study. Nutrients, 18(9), Article 1360. https://doi.org/10.3390/nu18091360
- Chong, M. Y., Koster, A., de Galan, B. E., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Bours, M. J. L., Weijenberg, M. P., & Eussen, S. J. P. M. (2026). Associations between chrono-nutrition and glucose metabolism across levels of glucose impairment: The Maastricht Study. European Journal of Nutrition, 65(4), Article 119. https://doi.org/10.1007/s00394-026-03964-2
- Phillips, N. E., Ajdacic-Gross, V., Rebeaud, J., Thevoz, G., Iaquinto, S., Baum, C., Kamm, C. P., Kuhle, J., Rapold, I., Roth, P., Zecca, C., von Wyl, V., Eussen, S. J. P. M., Steinemann, N., Pot, C., & Collet, T.-H. (2026). Associations of chrononutrition and sleep with fatigue in multiple sclerosis: an analysis of the Swiss Multiple Sclerosis Registry. BMJ Neurology Open, 8(1), Article e001471. https://doi.org/10.1136/bmjno-2025-001471
- Chong, M. Y., Koster, A., Meertens, R. M., Pot, G. K., Galan, B. E. D., Kallen, C. J. H. V. D., Savelberg, H. H. C. M., Bosma, H., Simons, S. O., Bours, M. J. L., Weijenberg, M. P., & Eussen, S. J. P. M. (2026). Associations of chrono-nutrition with sleep and quality of life: The Maastricht Study. Clinical Nutrition, 59, Article 106593. https://doi.org/10.1016/j.clnu.2026.106593
- Weerts, J., Voorrips, S. N., Jeneson, J. A. L., Barandiaran Aizpurua, A., Mevenkamp, J., Sibeijn-Kuiper, A. J., Renken, R. J., Schroen, B. L. M., Knackstedt, C., Houben, A. J. H. M., van der Meer, P., Schrauwen-Hinderling, V. B., Westenbrink, B. D., & van Empel, V. P. M. (2026). Quantifying skeletal muscle energy metabolism during exercise in heart failure with preserved ejection fraction using in vivo <SUP>31</SUP>P magnetic resonance spectroscopy. Esc heart failure, 13(2), Article xvaf035. https://doi.org/10.1093/eschf/xvaf035
- Chong, M. Y., Henson, J., Bours, M. J. L., Bosma, H., de Galan, B. E., van der Kallen, C. J. H., Meertens, R. M., Savelberg, H. H. C. M., Schram, M. T., Weijenberg, M. P., Yates, T., Koster, A., & Eussen, S. J. P. M. (2026). Physical activity and meal timing alignment with chronotype and their associations with glucose metabolism: The Maastricht Study. Diabetes Obesity & Metabolism, 28(4), 3295-3304. https://doi.org/10.1111/dom.70526
- Chong, M. Y., Eussen, S. J. P. M., van der Velde, J. H. P. M., de Galan, B. E., Savelberg, H. H. C. M., Bosma, H., Bours, M. J. L., Weijenberg, M. P., & Koster, A. (2026). Reallocating morning physical activity to later-day activity and its association with type 2 diabetes incidence: The Maastricht Study. Diabetes Obesity & Metabolism, 28(4), 2642-2650. https://doi.org/10.1111/dom.70438
- Kiesswetter, E., Schwarzer, G., Stadelmaier, J., Lohner, S., Grummich, K., Dagnelie, P. C., Beck, A. M., Beelen, J., Botella-Carretero, J. I., Faxén-Irving, G., Hickson, M., Iff, S., Johansen, A., Sharma, Y., Sorensen, J. M., Kaegi-Braun, N., Wunderle, C., Bongaerts, B., Meerpohl, J. J., ... Schwingshackl, L. (2026). Oral nutritional interventions in hospitalised older people at nutritional risk: a network meta-analysis of individual participant data. Cochrane Database of Systematic Reviews, 3, Article CD015468. https://doi.org/10.1002/14651858.CD015468.pub2
- Maasen, K., Mayen, A.-L., Hana, C., Knaze, V., Van Greevenbroek, M. M. J., Eussen, S. J. P. M., Debras, C., Stehouwer, C. D. A., Tjonneland, A., Kyro, C., Ibsen, D. B., Dah, C. C., Mancini, F., Laouali, N., Hajji, M., Schulze, M. B., Bajracharya, R., Katzke, V., Masala, G., ... Schalkwijk, C. G. (2026). Higher intake of dietary dicarbonyl compounds is associated with lower incidence of type 2 diabetes: European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct case-cohort study. European Journal of Nutrition, 65(3), Article 98. https://doi.org/10.1007/s00394-026-03904-0
- Ferrero, G., Mastrocola, R., Tarallo, S., Pardini, B., Scheijen, J., Van De Waarenburg, M., Gallo, G., Chatziioannou, A. C., Robinot, N., Keski-Rahkonen, P., Piccinno, G., Segata, N., Aglago, E. K., Hughes, D. J., Jenab, M., Schalkwijk, C. G., & Naccarati, A. (2026). Integrative analyses of dicarbonyls and advanced glycation end-products with multiomic profiles across tissue, plasma and stool samples reveal methylglyoxal accumulation in colon cancer. Free Radical Biology and Medicine, 246, 518-530. https://doi.org/10.1016/j.freeradbiomed.2026.01.034
- Schaarup, J. R., Bjerg, L., Hansen, C. S., Andersen, S. T., van Greevenbroek, M. M. J., Schram, M. T., De Galan, B. E., Stehouwer, C., & Witte, D. R. (2026). Cardiovascular autonomic dysfunction is linked with arterial stiffness across glucose metabolism: the Maastricht study. BMJ Open Diabetes Research & Care, 14(2), Article e004995. https://doi.org/10.1136/bmjdrc-2025-004995
- Berends, E., Eussen, S. J. P. M., Backes, W. H., Dagnelie, P. C., Jansen, J. F. A., Galan, B. E. D., Greevenbroek, M. M. J. V., Kohler, S., Schram, M. T., Wesselius, A., Oostenbrugge, R. J., Foulquier, S., & Schalkwijk, C. G. (2026). Associations between methylglyoxal and cerebral small vessel disease and cognitive function-The Maastricht Study. Journal of Stroke & Cerebrovascular Diseases, 35(3), Article 108578. https://doi.org/10.1016/j.jstrokecerebrovasdis.2026.108578
- Wang, K., Kroon, A. A., De Galan, B. E., Berendschot, T. T. J. M., Schram, M. T., Houben, A. J. H. M., & van Greevenbroek, M. M. J. (2026). Associations of blood pressure with retinal arteriolar narrowing and urinary albumin excretion are modified by prediabetes: the Maastricht study. Journal of Hypertension, 44(3), 461-469. https://doi.org/10.1097/HJH.0000000000004225
- van Baal, T. L., Köhler, S., Koster, A., Meertens, R. M., Bosma, H., Schram, M. T., Jansen, J. F. A., Simons, S. O., de Galan, B. E., Eussen, S. J. P. M., Janssen, N., & Deckers, K. (2026). The association between sleep parameters, cognitive functioning, and markers of brain morphology: The Maastricht Study. Sleep, 49(3), Article zsaf218. https://doi.org/10.1093/sleep/zsaf218
- Drenthen, G. S., Backes, W. H., Kohler, S., Deckers, K., Schram, M. T., Eussen, S. J. P. M., Jansen, W. J., & Jansen, J. F. A. (2026). The role of modifiable risk factors on the cerebral myelin content and cognition: findings from The Maastricht Study. Geroscience. Advance online publication. https://doi.org/10.1007/s11357-026-02206-x
- Setjiadi, D., Delles, C., Kroon, A. A., Ressink, K., Bekers, O., Meex, S. J. R., Köhler, S., Kooman, J. P., Jansen, J. F. A., Brunner-La Rocca, H.-P., Wesselius, A., Houben, A. J. H. M., & van Greevenbroek, M. M. J. (2026). Characterization of participants with a disproportionate degree of hypertension-mediated organ damage: the Maastricht study. Journal of Hypertension, 44, 1329-1336. https://doi.org/10.1097/HJH.0000000000004265
- Maalmi, H., Wouters, K., Schaper, N. C., Zhu, A., Heijman, J., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Dagnelie, P. C., de Galan, B. E., Wesselius, A., Ziegler, D., Roden, M., Herder, C., Oluwagbemigun, K., & Stehouwer, C. D. A. (2026). Circulating Neutrophil and Monocyte Counts Are Inversely Associated With Heart Rate Variability Indices: The Maastricht Study. Journal of the American Heart Association, 15(3), 1-14. Article e043994. https://doi.org/10.1161/JAHA.125.043994
- Valente, M. J., Cao, B., Holthuijsen, D. D. B., Bours, M. J. L., Eussen, S. J. P. M., Weijenberg, M. P., & Rijnhart, J. J. M. (2026). Omission of main effects from regression models with a ratio variable as the focal exposure can result in bias and inflated type I error rates. Journal of Clinical Epidemiology, 190, Article 112092. https://doi.org/10.1016/j.jclinepi.2025.112092
- Visker, V. P., Kvist, A. V., Vestergaard, P., van den Bergh, J. P., Brouwers, M. C. J. G., Wyers, C. E., & Driessen, J. H. M. (2026). Fracture trends in Denmark from 1997 to 2021. Osteoporosis International, 37(2), 417-424. https://doi.org/10.1007/s00198-025-07746-0
- Dimitropoulou, N. M., Beran, M., Eussen, S. J. P. M., Dingena, C. F., Dagnelie, P. C., Van Der Kallen, C. J. H., Koster, A., Van Greevenbroek, M. M. J., Brouwers, M. C. G. J., Schram, M. T., & de Galan, B. E. (2026). Liver fat content is not elevated in people with type 1 diabetes: the Maastricht Study. Diabetologia, 69(2), 364-373. https://doi.org/10.1007/s00125-025-06597-y
- Jiang, Z., Waas, I. S. E., Simsek, S., Schalkwijk, C. G., Roelofs, J. J. T. H., Niessen, H. W. M., & Krijnen, P. A. J. (2026). N ε-(carboxymethyl)lysine-modified albumin exacerbates doxorubicin-induced NOX5-dependent oxidative stress in endothelial cells. Biochemical and Biophysical Research Communications, 796, Article 153135. https://doi.org/10.1016/j.bbrc.2025.153135
- Silvares, R. R., de Araujo, B. P., Pereira, E. N. G. D. S., Rodrigues, K. L., Barbosa, J. M. C., da Silva, J. F., da Silva, V. V. D., Van de Aarenburg, M., Scheijen, J., Wouters, K., Schalkwijk, C., & Daliry, A. (2026). Pyridoxamine reduces inflammatory and microcirculatory abnormalities in metabolic dysfunction-associated steatohepatitis and modulates key factors in the hepatic AGE/ALE signaling pathway. Frontiers in physiology, 16, Article 1736221. https://doi.org/10.3389/fphys.2025.1736221
- Tore, E. C., Briones, A. M., Bruno, R. M., Dalli, J., Eussen, S. J. P. M., Schalkwijk, C. G., & van Greevenbroek, M. M. J. (2026). Response to: Comment on “Plasma-based low-grade inflammation and endothelial dysfunction explain a small but significant proportion of the association between the n-3 polyunsaturated fatty acids and cardiovascular diseases: The Maastricht Study”. Journal of Clinical Lipidology. Advance online publication. https://doi.org/10.1016/j.jacl.2026.06.012
- Dimova, R., Tankova, T., Chakarova, N., van de Waarenburg, M., & Schalkwijk, C. G. (2026). The Interrelationship Between Cardiac Autonomic Activity and Low-Grade Inflammation in Subjects with Obesity and Prediabetes. Experimental and Clinical Endocrinology & Diabetes, 134(01), 10-18. https://doi.org/10.1055/a-2763-7764
- Hansen, E. K., Hansen, D., Schalkwijk, C., Waarenburg, M., Hansen, H. P., & Lindhard, K. (2026). The Effect of Far Infrared Treatment on Changes in Biomarkers in the Arteriovenous Fistula. Blood Purification, 55(1), 44-53. https://doi.org/10.1159/000547478
- Olsen, T., Elshorbagy, A., Tore, E. C., Bastani, N. E., Stolt, E., Blokland, G. A. M., Stehouwer, C. D. A., Kooi, M. E., Jansen, J. F. A., Eussen, S. J. P. M., Grootswagers, P., Refsum, H., Retterstol, K., Vinknes, K. J., van Greevenbroek, M. M. J., & Nichenametla, S. N. (2026). Higher plasma serine levels are associated with favorable values of metabolic health markers among middle-aged and older adults in The Maastricht Study. Geroscience. Advance online publication. https://doi.org/10.1007/s11357-026-02237-4
- 2025
- Theunissen, M., Lardenoye, S., van den Beuken-van Everdingen, M. H. J., & Stassen, P. M. (2025). The surprise question: predictive accuracy in an unselected emergency department population - a prospective study in nurses and physicians. Annals of Medicine, 57(1), Article 2529575. https://doi.org/10.1080/07853890.2025.2529575
- Chan, M. M., Daemen, S., Beatty, W., Byrnes, K., Cho, K., Ferguson, D., Feldstein, N., Park, C., Guo, Z., Park, A. C., Fu, C. F., Florczak, K. L., He, L., Yang, B. Q., Javaheri, A., Patti, G. J., Finck, B. N., Razani, B., & Schilling, J. D. (2025). Induction of TFEB promotes Kupffer cell survival and reduces lipid accumulation in MASLD. Hepatology communications, 9(12), Article e0853. https://doi.org/10.1097/HC9.0000000000000853
- Van Dam, P. M. E. L., Van Doorn, W. P. T. M., Sevenich, L., Lambriks, L., Cals, J. W. L., Bekers, O., Stassen, P. M., & Meex, S. J. R. (2025). Machine learning for risk stratification in the emergency department (MARS-ED): a randomized controlled trial. Nature Communications, 17(1), Article 242. https://doi.org/10.1038/s41467-025-66947-7
- van der Graaf, A., Warmerdam, R., Auwerx, C., Xie, M., Wood, A. R., Westra, H. J., Weiss, S., Völker, U., Visscher, P. M., Viñuela, A., Verlouw, J., Veldink, J., Tokolyi, A., Teumer, A., Souto, J. C., Soria, J. M., Slagboom, E., Singleton, A., Raitoharju, E., ... eQTLgen Consortium (2025). MR-link-2: pleiotropy robust cis Mendelian randomization validated in three independent reference datasets of causality. Nature Communications, 16(1), Article 6112. https://doi.org/10.1038/s41467-025-60868-1
- van Oeteren, M. A. J., De Groot, D. M., Buziau, A. M., Scheijen, J. L. J. M., van de Waarenburg, M. P. H., Kroon, A. A., Eussen, S. J. P. M., Dagnelie, P. C., Van Greevenbroek, M. M. J., Houben, A. J. H. M., Meex, S. J. R., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). The effects of dietary fructose on blood pressure are modified by the food matrix. Clinical Nutrition, 55, 134-140. https://doi.org/10.1016/j.clnu.2025.10.017
- Meisters, R., Koster, A., Sezer, B., Albers, J., van Greevenbroek, M., de Galan, B., & Bosma, H. (2025). The importance of material deprivation in type 2 diabetes incidence: longitudinal analyses in the Maastricht study. BMC Public Health, 25(1), Article 3013. https://doi.org/10.1186/s12889-025-24263-1
- Ahmadi, A., Gorji, H., Shashikant, S., Katz, R., Houben, A. J. H. M., Weinreb, R. N., Allison, M., Meuer, S. M., Klein, B. E., Cotch, M. F., Gutierrez, O. M., Sarnak, M. J., Shlipak, M., Ix, J. H., & Malhotra, R. (2025). Associations of Biomarkers of Kidney Tubule Health with Retinal Microvascular Signs: The Multi-Ethnic Study of Atherosclerosis (MESA). Kidney360, 6(12), 2157-2165. https://doi.org/10.34067/KID.0000000970
- Brouwers, M. C. G. J., Klop, B., Ribalta, J., & Cabezas, M. C. (2025). Familial Combined Hyperlipidemia: Myth or Reality?Current Atherosclerosis Reports, 27(1), Article 45. https://doi.org/10.1007/s11883-025-01289-9
- Pulsford, R. M., Bakker, E. A., Ahmadi, M., Blodgett, J. M., Bosma, H., Brocklebank, L., Eussen, S. J. P. M., Hamer, M., Lear, R., Metcalf, B., Savelberg, H., Stamatakis, E., & Koster, A. (2025). Not all steps are equal: independent prospective associations of stepping volume and patterns with incident type 2 diabetes mellitus in the Maastricht study. International Journal of Behavioral Nutrition and Physical Activity, 22(1), Article 145. https://doi.org/10.1186/s12966-025-01839-z
- Lasfar, A., van Stratum, S. L. M., Imperatrice, M., van Kalkeren, C. A. J., Scheijen, J. L. J. M., Schalkwijk, C. G., La Torre, D., & Troost, F. J. (2025). Effects of olive leaf extract supplementation on systemic markers of tissue aging and remodeling in postmenopausal women: a randomized controlled trial with exploratory skin outcomes. Frontiers in nutrition, 12, Article 1670194. https://doi.org/10.3389/fnut.2025.1670194



