• 2022
    • Evans, P. C., Davidson, S. M., Wojta, J., Bäck, M., Bollini, S., Brittan, M., Catapano, A. L., Chaudhry, B., Cluitmans, M., Gnecchi, M., Guzik, T. J., Hoefer, I., Madonna, R., Monteiro, J. P., Morawietz, H., Osto, E., Padró, T., Sluimer, J. C., Tocchetti, C. G., ... Weber, C. (2022). From novel discovery tools and biomarkers to precision medicine-basic cardiovascular science highlights of 2021/22. Cardiovascular Research, 118(13), 2754-2767. https://doi.org/10.1093/cvr/cvac114
    • Hettwer, J., Hinterdobler, J., Miritsch, B., Deutsch, M-A., Li, X., Mauersberger, C., Moggio, A., Braster, Q., Gram, H., Robertson, A. A. B., Cooper, M. A., Groß, O., Krane, M., Weber, C., Koenig, W., Soehnlein, O., Adamstein, N. H., Ridker, P., Schunkert, H., ... Sager, H. B. (2022). Interleukin-1β suppression dampens inflammatory leucocyte production and uptake in atherosclerosis. Cardiovascular Research, 118(13), 2778-2791. [337]. https://doi.org/10.1093/cvr/cvab337
    • Habenicht, L. K. L., Wang, Z. H., Zhang, X., Li, Y. F., Mogler, C., Huspenina, J. S., Schmid, R. M., Weber, C., Mohanta, S. K., Ma, Z., & Yin, C. J. (2022). The C1q-ApoE complex: A new hallmark pathology of viral hepatitis and nonalcoholic fatty liver disease. Frontiers in Immunology, 13, [970938]. https://doi.org/10.3389/fimmu.2022.970938
    • Brandhofer, M., Hoffmann, A., Blanchet, X., Siminkovitch, E., Rohlfing, A. K., El Bounkari, O., Nestele, J. A., Bild, A., Kontos, C., Hille, K., Rohde, V., Froehlich, A., Golemi, J., Gokce, O., Krammer, C., Scheiermann, P., Tsilimparis, N., Sachs, N., Kempf, W. E., ... Bernhagen, J. (2022). Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation. Cellular and Molecular Life Sciences, 79(10), [512]. https://doi.org/10.1007/s00018-022-04539-0
    • Nitz, K., Lacy, M., Bianchini, M., Wichapong, K., Kücükgöze, I. A., Bonfiglio, C. A., Migheli, R., Wu, Y., Burger, C., Li, Y., Forné, I., Ammar, C., Janjic, A., Mohanta, S., Duchene, J., Heemskerk, J. W. M., Megens, R. T. A., Schwedhelm, E., Huveneers, S., ... Atzler, D. (2022). The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function. Circulation Research, 131(8), 701-712. https://doi.org/10.1161/CIRCRESAHA.122.321094
    • Santovito, D., & Weber, C. (2022). Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease. Nature Reviews Cardiology, 19(9), 620-638. https://doi.org/10.1038/s41569-022-00680-2
    • Santovito, D., & Weber, C. (2022). Publisher Correction: Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease. Nature Reviews Cardiology, 19(9), 639-639. https://doi.org/10.1038/s41569-022-00733-6
    • Mohanta, S. K., Weber, C., Yin, C., & Habenicht, A. J. R. (2022). The dawn has come for new therapeutics to treat atherosclerosis: Targeting neuroimmune cardiovascular interfaces in artery brain circuits. Clinical and Translational Medicine, 12(9), [e1040]. https://doi.org/10.1002/ctm2.1040
    • van den Kerkhof, D. L., Nagy, M., Wichapong, K., Brouns, S. L. N., Suylen, D. P. L., Hackeng, T. M., & Dijkgraaf, I. (2022). Unraveling the role of the homoarginine residue in antiplatelet drug eptifibatide in binding to the αIIbβ3 integrin receptor. Thrombosis Research, 217, 96-103. https://doi.org/10.1016/j.thromres.2022.07.011
    • Taş, K., Volta, B. D., Lindner, C., El Bounkari, O., Hille, K., Tian, Y., Puig-Bosch, X., Ballmann, M., Hornung, S., Ortner, M., Prem, S., Meier, L., Rammes, G., Haslbeck, M., Weber, C., Megens, R. T. A., Bernhagen, J., & Kapurniotu, A. (2022). Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly. Nature Communications, 13(1), [5004]. https://doi.org/10.1038/s41467-022-32688-0
    • Farina, F. M., Santovito, D., & Weber, C. (2022). Two-Faced Janus: CCR2-Expressing Macrophages and Their Dual Role in Allograft Rejection of the Transplanted Heart. Circulation, 146(8), 639-642. https://doi.org/10.1161/CIRCULATIONAHA.122.061088
    • Huang, J., Jooss, N. J., Fernández, D. I., Sickmann, A., García, Á., Wichapong, K., Dijkgraaf, I., & Heemskerk, J. W. M. (2022). Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under Shear. International journal of molecular sciences, 23(15), [8688]. https://doi.org/10.3390/ijms23158688
    • Karshovska, E., Mohibullah, R., Zhu, M. Y., Zahedi, F., Thomas, D., Magkrioti, C., Geissler, C., Megens, R. T. A., Bianchini, M., Nazari-Jahantigh, M., Ferreiros, N., Aidinis, V., & Schober, A. (2022). Endothelial ENPP2 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 2) Increases Atherosclerosis in Female and Male Mice. Arteriosclerosis Thrombosis and Vascular Biology, 42(8), 1023-1036. https://doi.org/10.1161/ATVBAHA.122.317682
    • Rot, A., Gutjahr, J. C., Biswas, A., Aslani, M., Hub, E., Thiriot, A., von Andrian, U. H., Megens, R. T. A., Weber, C., & Duchene, J. (2022). Murine bone marrow macrophages and human monocytes do not express atypical chemokine receptor 1. Cell stem cell, 29(7), 1013-1015. https://doi.org/10.1016/j.stem.2021.11.010
    • Ferdinandy, P., Koller, Á., Weber, C., Wojta, J., & Waltenberger, J. (2022). Frontiers in CardioVascular Biomedicine (FCVB) 2022 Budapest is on in person! The excellent programme proves that scientists won against COVID-19. Cardiovascular Research, 118(8), E59-E61. https://doi.org/10.1093/cvr/cvac064
    • Gencer, S., Döring, Y., Jansen, Y., Bayasgalan, S., Yan, Y., Bianchini, M., Cimen, I., Müller, M., Peters, L. J. F., Megens, R. T. A., von Hundelshausen, P., Duchene, J., Lemnitzer, P., Soehnlein, O., Weber, C., & van der Vorst, E. P. C. (2022). Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium. Basic Research in Cardiology, 117(1), 17. [30]. https://doi.org/10.1007/s00395-022-00937-4
    • Liu, Y., Shi, J. Z., Jiang, R., Liu, S. F., He, Y. Y., van der Vorst, E. P. C., Weber, C., Doering, Y., & Yan, Y. (2022). Regulatory T Cell-Related Gene Indicators in Pulmonary Hypertension. Frontiers in Pharmacology, 13, [908783]. https://doi.org/10.3389/fphar.2022.908783
    • Georgakis, M. K., Bernhagen, J., Heitman, L. H., Weber, C., & Dichgans, M. (2022). Targeting the CCL2-CCR2 axis for atheroprotection. European Heart Journal, 43(19), 1799-1808. https://doi.org/10.1093/eurheartj/ehac094
    • Mohanta, S. K., Peng, L., Li, Y., Lu, S., Sun, T., Carnevale, L., Perrotta, M., Ma, Z., Förstera, B., Stanic, K., Zhang, C., Zhang, X., Szczepaniak, P., Bianchini, M., Saeed, B. R., Carnevale, R., Hu, D., Nosalski, R., Pallante, F., ... Habenicht, A. J. R. (2022). Neuroimmune cardiovascular interfaces control atherosclerosis. Nature, 605(7908), 152-159. https://doi.org/10.1038/s41586-022-04673-6
    • Koenen, R. R., & Weber, C. (2022). Jam-A Unleashed Incites Thromboinflammatory Coronary Artery Disease. JACC: Basic to Translational Science, 7(5), 462-464. https://doi.org/10.1016/j.jacbts.2022.03.014
    • Leberzammer, J., Agten, S. M., Blanchet, X., Duan, R., Ippel, H., Megens, R. T. A., Schulz, C., Aslani, M., Duchene, J., Döring, Y., Jooss, N. J., Zhang, P., Brandl, R., Stark, K., Siess, W., Jurk, K., Heemskerk, J. W. M., Hackeng, T. M., Mayo, K. H., ... von Hundelshausen, P. (2022). Targeting platelet-derived CXCL12 impedes arterial thrombosis. Blood, 139(17), 2691-2705. https://doi.org/10.1182/blood.2020010140
    • Peters, L. J. F., Baaten, C. C. F. M. J., Maas, S. L., Lu, C., Nagy, M., Jooss, N. J., Bidzhekov, K., Santovito, D., Moreno-Andrés, D., Jankowski, J., Biessen, E. A. L., Döring, Y., Heemskerk, J. W. M., Weber, C., Kuijpers, M. J. E., & van der Vorst, E. P. C. (2022). MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice. Biomedicines, 10(5), [983]. https://doi.org/10.3390/biomedicines10050983
    • Poelman, H., Ippel, H., Gurkan, B., Boelens, R., Vriend, G., van 't Veer, C., Lutgens, E., & Nicolaes, G. A. F. (2022). Structural anomalies in a published NMR-derived structure of IRAK-M. Journal of Molecular Graphics & Modelling, 111, [108061]. https://doi.org/10.1016/j.jmgm.2021.108061
    • Hrdinova, J., Fernández, D. I., Ercig, B., Tullemans, B. M. E., Suylen, D. P. L., Agten, S. M., Jurk, K., Hackeng, T. M., Vanhoorelbeke, K., Voorberg, J., Reutelingsperger, C. P. M., Wichapong, K., Heemskerk, J. W. M., & Nicolaes, G. A. F. (2022). Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear. International journal of molecular sciences, 23(4), [2046]. https://doi.org/10.3390/ijms23042046
    • van der Laan, K. W. F., Reesink, K. D., van der Bruggen, M. M., Jaminon, A. M. G., Schurgers, L. J., Megens, R. T. A., Huberts, W., Delhaas, T., & Spronck, B. (2022). Improved Quantification of Cell Density in the Arterial Wall-A Novel Nucleus Splitting Approach Applied to 3D Two-Photon Laser-Scanning Microscopy. Frontiers in physiology, 12, [814434]. https://doi.org/10.3389/fphys.2021.814434
    • Lip, G. Y. H., Rigby, A., & Weber, C. (2022). A Rollercoaster Plunge into 2022. Thrombosis and Haemostasis, 122(1), 1-4. https://doi.org/10.1055/s-0041-1741073
    • Weber, C., Rigby, A., & Lip, G. Y. H. (2022). Thrombosis and Haemostasis 2021 Editors' Choice Papers. Thrombosis and Haemostasis, 122(01), 163-170. https://doi.org/10.1055/s-0041-1741072
    • Uengwetwanit, T., Chutiwitoonchai, N., Wichapong, K., & Karoonuthaisiri, N. (2022). Identification of novel SARS-CoV-2 RNA dependent RNA polymerase (RdRp) inhibitors: From in silico screening to experimentally validated inhibitory activity. Computational and Structural Biotechnology Journal, 20, 882-890. https://doi.org/10.1016/j.csbj.2022.02.001
  • 2021
    • He, Y. Y., Xie, X. M., Zhang, H. D., Ye, J., Gencer, S., van der Vorst, E. P. C., Doering, Y., Weber, C., Pang, X. B., Jing, Z. C., Yan, Y., & Han, Z. Y. (2021). Corrigendum: Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension. Frontiers in Pharmacology, 12, [810178]. https://doi.org/10.3389/fphar.2021.810178
    • von Hundelshausen, P., Wichapong, K., Gabius, H. J., & Mayo, K. H. (2021). The marriage of chemokines and galectins as functional heterodimers. Cellular and Molecular Life Sciences, 78(24), 8073-8095. https://doi.org/10.1007/s00018-021-04010-6
    • Natarelli, L., Virgili, F., & Weber, C. (2021). SARS-CoV-2, Cardiovascular Diseases, and Noncoding RNAs: A Connected Triad. International journal of molecular sciences, 22(22), [12243]. https://doi.org/10.3390/ijms222212243
    • He, Y. Y., Xie, X. M., Zhang, H. D., Ye, J., Gencer, S., van der Vorst, E. P. C., Doering, Y., Weber, C., Pang, X. B., Jing, Z. C., Yan, Y., & Han, Z. Y. (2021). Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension. Frontiers in Pharmacology, 12, [753727]. https://doi.org/10.3389/fphar.2021.753727
    • Bervoets, L., Ippel, J. H., Smolinska, A., van Best, N., Savelkoul, P. H. M., Mommers, M. A. H., & Penders, J. (2021). Practical and Robust NMR-Based Metabolic Phenotyping of Gut Health in Early Life. Journal of Proteome Research, 20(11), 5079-5087. https://doi.org/10.1021/acs.jproteome.1c00617
    • van der Beelen, S. H. E., Agten, S. M., Suylen, D. P. L., Wichapong, K., Hrdinova, J., Mees, B. M. E., Spronk, H. M. H., & Hackeng, T. M. (2021). Letter: In response to a recent letter by Prior et al.Thrombosis Research, 207, 66-66. https://doi.org/10.1016/j.thromres.2021.06.017
    • Gissler, M. C., Scherrer, P., Anto-Michel, N., Pennig, J., Hoppe, N., Funer, L., Hardtner, C., Stachon, P., Li, X. W., Mitre, L. S., Marchini, T., Madl, J., Wadle, C., Hilgendorf, I., von zur Muhlen, C., Bode, C., Weber, C., Lutgens, E., Wolf, D., ... Willecke, F. (2021). Deficiency of Endothelial CD40 Induces a Stable Plaque Phenotype and Limits Inflammatory Cell Recruitment to Atherosclerotic Lesions in Mice. Thrombosis and Haemostasis, 121(11), 1530-1540. https://doi.org/10.1055/a-1397-1858
    • Lesch, S., Blumenberg, V., Stoiber, S., Gottschlich, A., Ogonek, J., Cadilha, B. L., Dantes, Z., Rataj, F., Dorman, K., Lutz, J., Karches, C. H., Heise, C., Kurzay, M., Larimer, B. M., Grassmann, S., Rapp, M., Nottebrock, A., Kruger, S., Tokarew, N., ... Kobold, S. (2021). T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours. Nature Biomedical Engineering, 5(11), 1246–1260. https://doi.org/10.1038/s41551-021-00737-6
    • von Hundelshausen, P., Lorenz, R., Siess, W., & Weber, C. (2021). Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT): Targeting Pathomechanisms with Bruton Tyrosine Kinase Inhibitors. Thrombosis and Haemostasis, 121(11), 1395-1399. https://doi.org/10.1055/a-1481-3039
    • Hinterdobler, J., Schott, S., Jin, H., Meesmann, A., Steinsiek, A. L., Zimmermann, A. S., Wobst, J., Muller, P., Mauersberger, C., Vilne, B., Baecklund, A., Chen, C. S., Moggio, A., Braster, Q., Molitor, M., Krane, M., Kempf, W. E., Ladwig, K. H., Hristov, M., ... Sager, H. B. (2021). Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis. European Heart Journal, 42(39), 4077-+. https://doi.org/10.1093/eurheartj/ehab371
    • Ercig, B., Arfman, T., Hrdinova, J., Wichapong, K., Reutelingsperger, C. P. M., Vanhoorelbeke, K., Nicolaes, G. A. F., & Voorberg, J. (2021). Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity. Journal of Biological Chemistry, 297(4), [101132]. https://doi.org/10.1016/j.jbc.2021.101132
    • Schober, A., Blay, R. M., Maleki, S. S., Zahedi, F., Winklmaier, A. E., Kakar, M. Y., Baatsch, I. M., Zhu, M. Y., Geissler, C., Fusco, A. E., Eberlein, A., Li, N., Megens, R. T. A., Banafsche, R., Kumbrink, J., Weber, C., & Nazari-Jahantigh, M. (2021). MicroRNA-21 Controls Circadian Regulation of Apoptosis in Atherosclerotic Lesions. Circulation, 144(13), 1059-1073. https://doi.org/10.1161/CIRCULATIONAHA.120.051614
    • Duan, R. D., Goldmann, L., Brandl, R., Spannagl, M., Weber, C., Siess, W., & von Hundelshausen, P. (2021). Effects of the Btk-Inhibitors Remibrutinib (LOU064) and Rilzabrutinib (PRN1008) With Varying Btk Selectivity Over Tec on Platelet Aggregation and in vitro Bleeding Time. Frontiers in cardiovascular medicine, 8, [749022]. https://doi.org/10.3389/fcvm.2021.749022
    • van der Vorst, E. P. C., Pepe, M. A. A., Peters, L. J. F., Haberbosch, M., Jansen, Y., Naumann, R., Stathopoulos, G. T., Weber, C., & Bidzhekov, K. (2021). Correction to: Transcriptome signature of miRNA-26b KO mouse model suggests novel targets. BMC Genomic Data, 22(1), [36]. https://doi.org/10.1186/s12863-021-00990-3
    • Huckriede, J., de Vries, F., Hultstroem, M., Wichapong, K., Reutelingsperger, C., Lipcsey, M., de Frutos, P. G., Frithiof, R., & Nicolaes, G. A. F. (2021). Histone H3 Cleavage in Severe COVID-19 ICU Patients. Frontiers in Cellular and Infection Microbiology, 11, [694186]. https://doi.org/10.3389/fcimb.2021.694186
    • Davidson, S. M., Padro, T., Bollini, S., Vilahur, G., Duncker, D. J., Evans, P. C., Guzik, T., Hoefer, I. E., Waltenberger, J., Wojta, J., & Weber, C. (2021). Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart. Cardiovascular Research, 117(10), 2161-2174. https://doi.org/10.1093/cvr/cvab200
    • Huckriede, J., Anderberg, S. B., Morales, A., de Vries, F., Hultstrom, M., Bergqvist, A., Ortiz-Perez, J. T., Sels, J. W., Wichapong, K., Lipcsey, M., van de Poll, M., Larsson, A., Luther, T., Reutelingsperger, C., Garcia de Frutos, P., Frithiof, R., & Nicolaes, G. A. F. (2021). Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients. Scientific Reports, 11(1), [15701]. https://doi.org/10.1038/s41598-021-95209-x
    • Bosmans, L. A., Shami, A., Atzler, D., Weber, C., Goncalves, I., & Lutgens, E. (2021). Glucocorticoid induced TNF receptor family-related protein (GITR)-A novel driver of atherosclerosis. Vascular Pharmacology, 139, [106884]. https://doi.org/10.1016/j.vph.2021.106884
    • Yan, Y., Thakur, M., van der Vorst, E. P. C., Weber, C., & Doering, Y. (2021). Targeting the chemokine network in atherosclerosis. Atherosclerosis, 330, 95-106. https://doi.org/10.1016/j.atherosclerosis.2021.06.912