• 2024
    • Wang, Y., Li, G., Chen, B., Shakir, G., Volz, M., van der Vorst, E. P. C., Maas, S. L., Geiger, M., Jethwa, C., Bartelt, A., Li, Z., Wettich, J., Sachs, N., Maegdefessel, L., Nazari Jahantigh, M., Hristov, M., Lacy, M., Lutz, B., Weber, C., ... Steffens, S. (2024). Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner. Cardiovascular Research. Advance online publication. https://doi.org/10.1093/cvr/cvae125
    • Mohanta, S. K., Santovito, D., & Weber, C. (2024). Cortico-limbic restructuring and atherosclerosis: a stressful liaison. European Heart Journal, 45(19), 1765-1767. https://doi.org/10.1093/eurheartj/ehae212
    • Frenz-Wiessner, S., Fairley, S. D., Buser, M., Goek, I., Salewskij, K., Jonsson, G., Illig, D., zu Putlitz, B., Petersheim, D., Li, Y., Chen, P. H., Kalauz, M., Conca, R., Sterr, M., Geuder, J., Mizoguchi, Y., Megens, R. T. A., Linder, M. I., Kotlarz, D., ... Klein, C. (2024). Generation of complex bone marrow organoids from human induced pluripotent stem cells. Nature Methods, 21(5), 868-881. https://doi.org/10.1038/s41592-024-02172-2
    • Döring, Y., van der Vorst, E. P. C., & Weber, C. (2024). Targeting immune cell recruitment in atherosclerosis. Nature reviews. Cardiology. Advance online publication. https://doi.org/10.1038/s41569-024-01023-z
    • Strohm, L., Daiber, A., Ubbens, H., Krishnankutty, R., Oelze, M., Kuntic, M., Hahad, O., Klein, V., Hoefer, I. E., von Kriegsheim, A., Kleinert, H., Atzler, D., Lurz, P., Weber, C., Wild, P. S., Münzel, T., Knosalla, C., Lutgens, E., & Daub, S. (2024). Role of inflammatory signaling pathways involving the CD40-CD40L-TRAF cascade in diabetes and hypertension-insights from animal and human studies. Basic Research in Cardiology. Advance online publication. https://doi.org/10.1007/s00395-024-01045-1
    • Vos, W. G., van Os, B. W., den Toom, M., Beckers, L., van Roomen, C. P. A. A., van Tiel, C. M., Mohapatra, B. C., Band, H., Nitz, K., Weber, C., Atzler, D., de Winther, M. P. J., Bosmans, L. A., Lutgens, E., & Seijkens, T. T. P. (2024). T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation. Frontiers in Immunology, 15, Article 1297893. https://doi.org/10.3389/fimmu.2024.1297893
    • Döring, Y., van der Vorst, E. P. C., Yan, Y., Neideck, C., Blanchet, X., Jansen, Y., Kemmerich, M., Bayasgalan, S., Peters, L. J. F., Hristov, M., Bidzhekov, K., Yin, C., Zhang, X., Leberzammer, J., Li, Y., Park, I., Kral, M., Nitz, K., Parma, L., ... Weber, C. (2024). Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis. Nature cardiovascular research, 3(2), 221-242. https://doi.org/10.1038/s44161-023-00413-9
    • Lip, G. Y. H., Rigby, A., & Weber, C. (2024). A Happy New Year 2024 from Thrombosis and Haemostasis!Thrombosis and Haemostasis, 124(1), 1-3. https://doi.org/10.1055/s-0043-1778033
    • Weber, C., Rigby, A., & Lip, G. Y. H. (2024). Thrombosis and Haemostasis 2023 Editors' Choice Papers. Thrombosis and Haemostasis, 124(1), 80-87. https://doi.org/10.1055/s-0043-1778032
    • Guerkan, B., Poelman, H., Pereverzeva, L., Kruijswijk, D., de Vos, A. F., Groenen, A. G., Nollet, E. E., Wichapong, K., Lutgens, E., van der Poll, T., Du, J., Wiersinga, W. J., Nicolaes, G. A. F., & van 't Veer, C. (2024). The IRAK-M death domain: a tale of three surfaces. Frontiers in Molecular Biosciences, 10, Article 1265455. https://doi.org/10.3389/fmolb.2023.1265455
  • 2023
    • Kral, M., van der Vorst, E. P. C., Surnov, A., Weber, C., & Doering, Y. (2023). ILC2-mediated immune crosstalk in chronic (vascular) inflammation. Frontiers in Immunology, 14, Article 1326440. https://doi.org/10.3389/fimmu.2023.1326440
    • Huckriede, J. B., Beurskens, D. M. H., Wildhagen, K. C. C. A., Reutelingsperger, C. P. M., Wichapong, K., & Nicolaes, G. A. F. (2023). Design and characterization of novel activated protein C variants for the proteolysis of cytotoxic extracellular histone H3. Journal of Thrombosis and Haemostasis, 21(12), 3557-3567. https://doi.org/10.1016/j.jtha.2023.08.023
    • Cimen, I., Natarelli, L., Abedi Kichi, Z., Henderson, J. M., Farina, F. M., Briem, E., Aslani, M., Megens, R. T. A., Jansen, Y., Mann-Fallenbuchel, E., Gencer, S., Duchêne, J., Nazari-Jahantigh, M., van der Vorst, E. P. C., Enard, W., Döring, Y., Schober, A., Santovito, D., & Weber, C. (2023). Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice. Science translational medicine, 15(720), Article eadf3357. https://doi.org/10.1126/scitranslmed.adf3357
    • Bianchini, M., Moeller-Ramon, Z., Weber, C., Megens, R., & Duchene, J. (2023). Short-term western diet causes rapid and lasting alterations of bone marrow physiology. Thrombosis and Haemostasis, 123(11), 1100-1104. https://doi.org/10.1055/a-2149-4431
    • Pekayvaz, K., Gold, C., Hoseinpour, P., Engel, A., Martinez-Navarro, A., Eivers, L., Coletti, R., Joppich, M., Dionísio, F., Kaiser, R., Tomas, L., Janjic, A., Knott, M., Mehari, F., Polewka, V., Kirschner, M., Boda, A., Nicolai, L., Schulz, H., ... Stark, K. (2023). Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation. Immunity, 56(10), 2325-2341.e15. https://doi.org/10.1016/j.immuni.2023.08.002
    • Wagner, J. U. G., Tombor, L. S., Malacarne, P. F., Kettenhausen, L. M., Panthel, J., Kujundzic, H., Manickam, N., Schmitz, K., Cipca, M., Stilz, K. A., Fischer, A., Muhly-Reinholz, M., Abplanalp, W. T., John, D., Mohanta, S. K., Weber, C., Habenicht, A. J. R., Buchmann, G. K., Angendohr, S., ... Dimmeler, S. (2023). Aging impairs the neurovascular interface in the heart. Science, 381(6660), 897-906. https://doi.org/10.1126/science.ade4961
    • Chai, J., Wu, J., Li, J., Liao, H., Lu, W., Guo, R., Shao, Z., Jmel, M. A., Martins, L. A., Hackeng, T., Ippel, H., Dijkgraaf, I., Kotsyfakis, M., & Xu, X. (2023). Novel Amphibian Bowman-Birk-Like Inhibitor with Antioxidant and Anticoagulant Effects Ameliorates Pancreatitis Symptoms in Mice. Journal of Medicinal Chemistry, 66(17), 11869-11880. https://doi.org/10.1021/acs.jmedchem.3c00475
    • Sachs, S., Götz, A., Finan, B., Feuchtinger, A., DiMarchi, R. D., Döring, Y., Weber, C., Tschöp, M. H., Müller, T. D., & Hofmann, S. M. (2023). GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease. Cardiovascular Diabetology, 22(1), Article 217. https://doi.org/10.1186/s12933-023-01940-2
    • Weber, C., Habenicht, A. J. R., & von Hundelshausen, P. (2023). Novel mechanisms and therapeutic targets in atherosclerosis: inflammation and beyond. European Heart Journal, 44(29), 2672-2681. https://doi.org/10.1093/eurheartj/ehad304
    • Wang, R., Damanik, F., Kuhnt, T., Jaminon, A., Hafeez, S., Liu, H., Ippel, H., Dijkstra, P. J., Bouvy, N., Schurgers, L., ten Cate, A. T., Dias, A., Moroni, L., & Baker, M. B. (2023). Biodegradable Poly(ester) Urethane Acrylate Resins for Digital Light Processing: From Polymer Synthesis to 3D Printed Tissue Engineering Constructs. Advanced Healthcare Materials, 12(17), Article 2202648. https://doi.org/10.1002/adhm.202202648
    • Reiche, M. E., Poels, K., Bosmans, L. A., Vos, W. G., Van Tiel, C. M., Gijbels, M. J. J., Aarts, S. A. B. M., Den Toom, M., Beckers, L., Weber, C., Atzler, D., Rensen, P. C. N., Kooijman, S., & Lutgens, E. (2023). Adipocytes control hematopoiesis and inflammation through CD40 signaling. Haematologica-the Hematology Journal, 108(7), 1873-1885. https://doi.org/10.3324/haematol.2022.281482
    • Blanchet, X., Weber, C., & von Hundelshausen, P. (2023). Chemokine Heteromers and Their Impact on Cellular Function-A Conceptual Framework. International Journal of Molecular Sciences, 24(13), Article 10925. https://doi.org/10.3390/ijms241310925
    • Farina, F. M., Weber, C., & Santovito, D. (2023). The emerging landscape of non-conventional RNA functions in atherosclerosis. Atherosclerosis, 374(1), 74-86. https://doi.org/10.1016/j.atherosclerosis.2023.01.009
    • Bosmans, L. A., van Tiel, C. M., Aarts, S. A. B. M., Willemsen, L., Baardman, J., van Os, B. W., den Toom, M., Beckers, L., Ahern, D. J., Levels, J. H. M., Jongejan, A., Moerland, P. D., Verberk, S. G. S., van den Bossche, J., de Winther, M. M. P. J., Weber, C., Atzler, D., Monaco, C., Gerdes, N., ... Lutgens, E. (2023). Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state. Cardiovascular Research, 119(5), 1146-1160. https://doi.org/10.1093/cvr/cvac084
    • Thomassen, M. C. L. G. D., Bouwens, B. R. C., Wichapong, K., Suylen, D. P., Bouwman, F. G., Hackeng, T. M., & Koenen, R. R. (2023). Protein arginine deiminase 4 inactivates tissue factor pathway inhibitor-alpha by enzymatic modification of functional arginine residues. Journal of Thrombosis and Haemostasis, 21(5), 1214-1226. https://doi.org/10.1016/j.jtha.2023.01.017
    • Bonfiglio, C. A., Weber, C., Atzler, D., & Lutgens, E. (2023). Immunotherapy and cardiovascular diseases: novel avenues for immunotherapeutic approaches. QJM: An International Journal of Medicine, 116(4), 271-278. https://doi.org/10.1093/qjmed/hcab207
    • Egea, V., Megens, R. T. A., Santovito, D., Wantha, S., Brandl, R., Siess, W., Khani, S., Soehnlein, O., Bartelt, A., Weber, C., & Ries, C. (2023). Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques. Cardiovascular Research, 119(1), 155-166. Article cvac022. https://doi.org/10.1093/cvr/cvac022
    • Van Os, B. W., Vos, W. G., Bosmans, L. A., Van Tiel, C. M., Lith, S. C., Den Toom, M. S., Beckers, L., Levels, J. H. M., Van Wouw, S. A. E., Zelcer, N., Zaal, E. A., Berkers, C. R., Van Der Lest, C. H. A., Helms, J. B., Weber, C., Atzler, D., De Winther, M. P. J., Baardman, J., & Lutgens, E. (2023). Hyperlipidaemia elicits an atypical, T helper 1-like CD4+T-cell response: A key role for very low-density lipoprotein. European heart journal open, 3(2), Article oead013. https://doi.org/10.1093/ehjopen/oead013
    • Wang, Z., Zhang, X., Lu, S., Zhang, C., Ma, Z., Su, R., Li, Y., Sun, T., Li, Y., Hong, M., Deng, X., Rafiee Monjezi, M., Hristov, M., Steffens, S., Santovito, D., Dornmair, K., Ley, K., Weber, C., Mohanta, S. K., ... Yin, C. (2023). Pairing of single-cell RNA analysis and T cell antigen receptor profiling indicates breakdown of T cell tolerance checkpoints in atherosclerosis. Nature cardiovascular research, 2(3), 290-306. https://doi.org/10.1038/s44161-023-00218-w
    • Krammer, C., Yang, B. S., Reichl, S., Besson-Girard, S., Ji, H., Bolini, V., Schulte, C., Noels, H., Schlepckow, K., Jocher, G., Werner, G., Willem, M., El Bounkari, O., Kapurniotu, A., Gokce, O., Weber, C., Mohanta, S., & Bernhagen, J. (2023). Pathways linking aging and atheroprotection in Mif- deficient atherosclerotic mice. Faseb Journal, 37(3), Article e22752. https://doi.org/10.1096/fj.202200056R
    • Chabronova, A., van den Akker, G. G. H., Housmans, B. A. C., Caron, M. M. J., Cremers, A., Surtel, D. A. M., Wichapong, K., Peffers, M. M. J., van Rhijn, L. W., Marchand, V., Motorin, Y., & Welting, T. J. M. (2023). Ribosomal RNA-based epitranscriptomic regulation of chondrocyte translation and proteome in osteoarthritis. Osteoarthritis and Cartilage, 31(3), 374-385. https://doi.org/10.1016/j.joca.2022.12.010
    • de Vries, F., Huckriede, J., Wichapong, K., Reutelingsperger, C., & Nicolaes, G. A. F. (2023). The role of extracellular histones in COVID-19. Journal of Internal Medicine, 293(3), 275-292. https://doi.org/10.1111/joim.13585
    • Pavlic, A., Poelman, H., Wasilewski, G., Wichapong, K., Lux, P., Maassen, C., Lutgens, E., Schurgers, L. J., Reutelingsperger, C. P., & Nicolaes, G. A. F. (2023). Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Calcification. International Journal of Molecular Sciences, 24(3), Article 2027. https://doi.org/10.3390/ijms24032027
    • Beukenhorst, A. L., Frallicciardi, J., Koch, C. M., Klap, J. M., Phillips, A., Desai, M. M., Wichapong, K., Nicolaes, G. A. F., Koudstaal, W., Alter, G., & Goudsmit, J. (2023). Corrigendum: The influenza hemagglutinin stem antibody CR9114: Evidence for a narrow evolutionary path towards universal protection ( vol 2 , 1049134 , 2022). Frontiers in Virology, 3, Article 1130102. https://doi.org/10.3389/fviro.2023.1130102
    • van der Vorst, E. P. C., Maas, S. L., Theodorou, K., Peters, L. J. F., Jin, H., Rademakers, T., Gijbels, M. J., Rousch, M., Jansen, Y., Weber, C., Lehrke, M., Lebherz, C., Yildiz, D., Ludwig, A., Bentzon, J. F., Biessen, E. A. L., & Donners, M. M. P. C. (2023). Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque hemorrhage and neovascularization in mice. Frontiers in Cardiovascular Medicine, 10(1), Article 974918. https://doi.org/10.3389/fcvm.2023.974918
    • Lip, G. Y. H., Rigby, A., & Weber, C. (2023). A Happy New Year 2023 from Thrombosis and Haemostasis. Thrombosis and Haemostasis, 123(1), 1-5. https://doi.org/10.1055/s-0042-1760264
    • Weber, C., Blanchet, X., & Lip, G. Y. H. (2023). Thrombosis and Haemostasis 2022 Editors' Choice Papers. Thrombosis and Haemostasis, 123(01), 123-130. https://doi.org/10.1055/s-0042-1760263
  • 2022
    • Beghi, S., Furmanik, M., Jaminon, A., Veltrop, R., Rapp, N., Wichapong, K., Bidar, E., Buschini, A., & Schurgers, L. J. (2022). Calcium Signalling in Heart and Vessels: Role of Calmodulin and Downstream Calmodulin-Dependent Protein Kinases. International journal of molecular sciences, 23(24), Article 16139. https://doi.org/10.3390/ijms232416139
    • Beukenhorst, A. L., Frallicciardi, J., Koch, C. M., Klap, J. M., Phillips, A., Desai, M. M., Wichapong, K., Nicolaes, G. A. F., Koudstaal, W., Alter, G., & Goudsmit, J. (2022). The influenza hemagglutinin stem antibody CR9114: Evidence for a narrow evolutionary path towards universal protection. Frontiers in Virology, 2, Article 1049134. https://doi.org/10.3389/fviro.2022.1049134
    • Guillamat-Prats, R., Hering, D., Derle, A., Rami, M., Härdtner, C., Santovito, D., Rinne, P., Bindila, L., Hristov, M., Pagano, S., Vuilleumier, N., Schmid, S., Janjic, A., Enard, W., Weber, C., Maegdefessel, L., Faussner, A., Hilgendorf, I., & Steffens, S. (2022). GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation. Nature cardiovascular research, 1, 1056-1071. https://doi.org/10.1038/s44161-022-00155-0
    • Evans, P. C., Davidson, S. M., Wojta, J., Bäck, M., Bollini, S., Brittan, M., Catapano, A. L., Chaudhry, B., Cluitmans, M., Gnecchi, M., Guzik, T. J., Hoefer, I., Madonna, R., Monteiro, J. P., Morawietz, H., Osto, E., Padró, T., Sluimer, J. C., Tocchetti, C. G., ... Weber, C. (2022). From novel discovery tools and biomarkers to precision medicine-basic cardiovascular science highlights of 2021/22. Cardiovascular Research, 118(13), 2754-2767. https://doi.org/10.1093/cvr/cvac114
    • Hettwer, J., Hinterdobler, J., Miritsch, B., Deutsch, M.-A., Li, X., Mauersberger, C., Moggio, A., Braster, Q., Gram, H., Robertson, A. A. B., Cooper, M. A., Groß, O., Krane, M., Weber, C., Koenig, W., Soehnlein, O., Adamstein, N. H., Ridker, P., Schunkert, H., ... Sager, H. B. (2022). Interleukin-1β suppression dampens inflammatory leucocyte production and uptake in atherosclerosis. Cardiovascular Research, 118(13), 2778-2791. Article 337. https://doi.org/10.1093/cvr/cvab337
    • Habenicht, L. K. L., Wang, Z. H., Zhang, X., Li, Y. F., Mogler, C., Huspenina, J. S., Schmid, R. M., Weber, C., Mohanta, S. K., Ma, Z., & Yin, C. J. (2022). The C1q-ApoE complex: A new hallmark pathology of viral hepatitis and nonalcoholic fatty liver disease. Frontiers in Immunology, 13, Article 970938. https://doi.org/10.3389/fimmu.2022.970938
    • Brandhofer, M., Hoffmann, A., Blanchet, X., Siminkovitch, E., Rohlfing, A. K., El Bounkari, O., Nestele, J. A., Bild, A., Kontos, C., Hille, K., Rohde, V., Froehlich, A., Golemi, J., Gokce, O., Krammer, C., Scheiermann, P., Tsilimparis, N., Sachs, N., Kempf, W. E., ... Bernhagen, J. (2022). Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation. Cellular and Molecular Life Sciences, 79(10), Article 512. https://doi.org/10.1007/s00018-022-04539-0
    • Nitz, K., Lacy, M., Bianchini, M., Wichapong, K., Kücükgöze, I. A., Bonfiglio, C. A., Migheli, R., Wu, Y., Burger, C., Li, Y., Forné, I., Ammar, C., Janjic, A., Mohanta, S., Duchene, J., Heemskerk, J. W. M., Megens, R. T. A., Schwedhelm, E., Huveneers, S., ... Atzler, D. (2022). The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function. Circulation Research, 131(8), 701-712. https://doi.org/10.1161/CIRCRESAHA.122.321094
    • Santovito, D., & Weber, C. (2022). Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease. Nature Reviews Cardiology, 19(9), 620-638. https://doi.org/10.1038/s41569-022-00680-2
    • Santovito, D., & Weber, C. (2022). Publisher Correction: Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease. Nature Reviews Cardiology, 19(9), 639-639. https://doi.org/10.1038/s41569-022-00733-6
    • Mohanta, S. K., Weber, C., Yin, C., & Habenicht, A. J. R. (2022). The dawn has come for new therapeutics to treat atherosclerosis: Targeting neuroimmune cardiovascular interfaces in artery brain circuits. Clinical and Translational Medicine, 12(9), Article e1040. https://doi.org/10.1002/ctm2.1040
    • van den Kerkhof, D. L., Nagy, M., Wichapong, K., Brouns, S. L. N., Suylen, D. P. L., Hackeng, T. M., & Dijkgraaf, I. (2022). Unraveling the role of the homoarginine residue in antiplatelet drug eptifibatide in binding to the αIIbβ3 integrin receptor. Thrombosis Research, 217, 96-103. https://doi.org/10.1016/j.thromres.2022.07.011