• 2022
    • Wang, S., Neumann, D., Westenbrink, B. D., Schianchi, F., Wong, L-Y., Sun, A., Strzelecka, A., Glatz, J. F. C., Luiken, J. J. F. P., & Nabben, M. (2022). Ketone Body Exposure of Cardiomyocytes Impairs Insulin Sensitivity and Contractile Function through Vacuolar-Type H+-ATPase Disassembly-Rescue by Specific Amino Acid Supplementation. International journal of molecular sciences, 23(21), [12909]. https://doi.org/10.3390/ijms232112909
    • Evans, P. C., Davidson, S. M., Wojta, J., Bäck, M., Bollini, S., Brittan, M., Catapano, A. L., Chaudhry, B., Cluitmans, M., Gnecchi, M., Guzik, T. J., Hoefer, I., Madonna, R., Monteiro, J. P., Morawietz, H., Osto, E., Padró, T., Sluimer, J. C., Tocchetti, C. G., ... Weber, C. (2022). From novel discovery tools and biomarkers to precision medicine-basic cardiovascular science highlights of 2021/22. Cardiovascular Research, 118(13), 2754-2767. https://doi.org/10.1093/cvr/cvac114
    • Madrigal-Matute, J., Cuervo, A. M., & Sluimer, J. C. (2022). CHAPERONE-MEDIATED AUTOPHAGY PROTECTS AGAINST ATHEROSCLEROSIS. Autophagy, 18(10), 2505-2507. https://doi.org/10.1080/15548627.2022.2096397
    • Wollenhaupt, J., Frisch, J., Harlacher, E., Wong, D. W. L., Jin, H., Schulte, C., Vondenhoff, S., Moellmann, J., Klinkhammer, B. M., Zhang, L., Baleanu-Curaj, A., Liehn, E. A., Speer, T., Kazakov, A., Werner, C., van der Vorst, E. P. C., Selejan, S-R., Hohl, M., Böhm, M., ... Noels, H. (2022). Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease. Redox Biology, 56, [102459]. https://doi.org/10.1016/j.redox.2022.102459
    • Ganesh, N., van der Vorst, E. P. C., Spiesshöfer, J., He, S., Burgmaier, M., Findeisen, H., Lehrke, M., Swirski, F. K., Marx, N., & Kahles, F. (2022). Gut immune cells-A novel therapeutical target for cardiovascular disease?Frontiers in cardiovascular medicine, 9, [943214]. https://doi.org/10.3389/fcvm.2022.943214
    • Torre, D., Schuwirth, L., Van der Vleuten, C., & Heeneman, S. (2022). An international study on the implementation of programmatic assessment: Understanding challenges and exploring solutions. Medical Teacher, 44(8), 928-937. https://doi.org/10.1080/0142159x.2022.2083487
    • Goossens, P., Lu, C., Cao, J., Gijbels, M. J., Karel, J. M. H., Wijnands, E., Claes, B. S. R., Fazzi, G. E., Hendriks, T. F. E., Wouters, K., Smirnov, E., van Zandvoort, M. J. M., Balluff, B., Cuypers, E., Donners, M. M. P. C., Heeren, R. M. A., & Biessen, E. A. L. (2022). Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context. Cell Metabolism, 34(8), 1214-1225.e6. https://doi.org/10.1016/j.cmet.2022.06.012
    • Jin, H., Maas, S. L., Lu, C., Nagenborg, J., Manca, M., Karel, J. M. H., Cavill, R., Waring, O., Sikkink, C. J. J. M., Mees, B. M. E., Daemen, M. J. A. P., Smirnov, E., Sluimer, J., Van der Vorst, E., & Biessen, E. A. L. (2022). Identification Of Cd8+T Cell Prdm1 In High-Risk Human Plaques And Its Regulatory Role In Murine Lesion Development. Atherosclerosis, 355, E9-E9.
    • Petsophonsakul, P., Burgmaier, M., Willems, B., Heeneman, S., Stadler, N., Gremse, F., Reith, S., Burgmaier, K., Kahles, F., Marx, N., Natour, E., Bidar, E., Jacobs, M., Mees, B., Reutelingsperger, C., Furmanik, M., & Schurgers, L. (2022). Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress and extracellular vesicle release in vascular smooth muscle cells. Cardiovascular Research, 118(9), 2196-2210. https://doi.org/10.1093/cvr/cvab244
    • Wang, S. J., Han, Y. Y., Nabben, M., Neumann, D., Luiken, J. J. F. P., & Glatz, J. F. C. (2022). Endosomal v-ATPase as a Sensor Determining Myocardial Substrate Preference. Metabolites, 12(7), [579]. https://doi.org/10.3390/metabo12070579
    • Maas, S. L., Jin, H., Lu, C., Nagenborg, J., Manca, M., Karel, J. M. H., Cavill, R., Waring, O., Sikkink, C. J. J. M., Mees, B. M. E., Daemen, M. J. A. P., Smirnov, E., Sluimer, J., van der Vorst, E. P. C., & Biessen, E. A. L. (2022). Identification of CD8+T cell PRDM1 in high-risk human plaques and its regulatory role in murine lesion development. Cardiovascular Research, 118(SUPPL 1). https://doi.org/10.1093/cvr/cvac066.186
    • Gencer, S., Döring, Y., Jansen, Y., Bayasgalan, S., Yan, Y., Bianchini, M., Cimen, I., Müller, M., Peters, L. J. F., Megens, R. T. A., von Hundelshausen, P., Duchene, J., Lemnitzer, P., Soehnlein, O., Weber, C., & van der Vorst, E. P. C. (2022). Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium. Basic Research in Cardiology, 117(1), 17. [30]. https://doi.org/10.1007/s00395-022-00937-4
    • Sluimer, J. C. (2022). RAC-king up Efferocytosis in Atherosclerotic Plaques With Aldehyde Dehydrogenase 2 Deficiency. Arteriosclerosis Thrombosis and Vascular Biology, 42(6), 717-718. https://doi.org/10.1161/ATVBAHA.122.317690
    • Liu, Y., Shi, J. Z., Jiang, R., Liu, S. F., He, Y. Y., van der Vorst, E. P. C., Weber, C., Doering, Y., & Yan, Y. (2022). Regulatory T Cell-Related Gene Indicators in Pulmonary Hypertension. Frontiers in Pharmacology, 13, [908783]. https://doi.org/10.3389/fphar.2022.908783
    • Christ, A., Goossens, P. G., Wijnands, E., Jin, H., Legein, B., Oth, T., Isaacs, A., Stoll, M., Vanderlocht, J., Lutgens, E., Daemen, M. J. A. P., Zenke, M., & Biessen, E. A. L. (2022). Low Density Lipoprotein Exposure of Plasmacytoid Dendritic Cells Blunts Toll-like Receptor 7/9 Signaling via NUR77. Biomedicines, 10(5), [1152]. https://doi.org/10.3390/biomedicines10051152
    • Evans, B. R., Yerly, A., van der Vorst, E. P. C., Baumgartner, I., Bernhard, S. M., Schindewolf, M., & Döring, Y. (2022). Inflammatory Mediators in Atherosclerotic Vascular Remodeling. Frontiers in cardiovascular medicine, 9, [868934]. https://doi.org/10.3389/fcvm.2022.868934
    • Puranitee, P., Kaewpila, W., Heeneman, S., van Mook, W. N. K. A., & Busari, J. O. (2022). Promoting a sense of belonging, engagement, and collegiality to reduce burnout: a mixed methods study among undergraduate medical students in a non-Western, Asian context. BMC Medical Education, 22(1), 327. [327]. https://doi.org/10.1186/s12909-022-03380-0
    • Peters, L. J. F., Baaten, C. C. F. M. J., Maas, S. L., Lu, C., Nagy, M., Jooss, N. J., Bidzhekov, K., Santovito, D., Moreno-Andrés, D., Jankowski, J., Biessen, E. A. L., Döring, Y., Heemskerk, J. W. M., Weber, C., Kuijpers, M. J. E., & van der Vorst, E. P. C. (2022). MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice. Biomedicines, 10(5), [983]. https://doi.org/10.3390/biomedicines10050983
    • Madrigal-Matute, J., de Bruijn, J., van Kuijk, K., Riascos-Bernal, D. F., Diaz, A., Tasset, I., Martín-Segura, A., Gijbels, M. J. J., Sander, B., Kaushik, S., Biessen, E. A. L., Tiano, S., Bourdenx, M., Krause, G. J., McCracken, I., Baker, A. H., Jin, H., Sibinga, N. E. S., Bravo-Cordero, J. J., ... Cuervo, A. M. (2022). Protective role of chaperone-mediated autophagy against atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America, 119(14), [2121133119]. https://doi.org/10.1073/pnas.2121133119
    • van Kuijk, K., Demandt, J. A. F., Perales-Patón, J., Theelen, T. L., Kuppe, C., Marsch, E., de Bruijn, J., Jin, H., Gijbels, M. J., Matic, L., Mees, B. M. E., Reutelingsperger, C. P. M., Hedin, U., Biessen, E. A. L., Carmeliet, P., Baker, A. H., Kramann, R. K., Schurgers, L. J., Saez-Rodriguez, J., & Sluimer, J. C. (2022). Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling. Cardiovascular Research, 118(5), 1232-1246. https://doi.org/10.1093/cvr/cvab152
    • van Dierendonck, X. A. M. H., Vrieling, F., Smeehuijzen, L., Deng, L., Boogaard, J. P., Croes, C. A., Temmerman, L., Wetzels, S., Biessen, E., Kersten, S., & Stienstra, R. (2022). Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages. Proceedings of the National Academy of Sciences of the United States of America, 119(12), [e2114739119]. https://doi.org/10.1073/pnas.2114739119
    • Van der Vorst, E. P. C., & Biessen, E. A. L. (2022). Unwrapped and uNCORked: PPAR-γ repression in atherosclerosis. European Heart Journal, 43(7), E32-E34. [ehz770]. https://doi.org/10.1093/eurheartj/ehz770
    • Haghikia, A., Zimmermann, F., Schumann, P., Jasina, A., Roessler, J., Schmidt, D., Heinze, P., Kaisler, J., Nageswaran, V., Aigner, A., Ceglarek, U., Cineus, R., Hegazy, A. N., van der Vorst, E. P. C., Döring, Y., Strauch, C. M., Nemet, I., Tremaroli, V., Dwibedi, C., ... Landmesser, U. (2022). Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism. European Heart Journal, 43(6), 518–533. https://doi.org/10.1093/eurheartj/ehab644
    • Kahles, F., Rau, M., Reugels, M., Foldenauer, A. C., Mertens, R. W., Arrivas, M. C., Schroder, J., Idel, P., Moellmann, J., van der Vorst, E. P. C., Marx, N., & Lehrke, M. (2022). The gut hormone glucose-dependent insulinotropic polypeptide is downregulated in response to myocardial injury. Cardiovascular Diabetology, 21(1), [18]. https://doi.org/10.1186/s12933-022-01454-3
    • Soppert, J., Frisch, J., Wirth, J., Hemmers, C., Boor, P., Kramann, R., Vondenhoff, S., Moellmann, J., Lehrke, M., Hohl, M., van der Vorst, E. P. C., Werner, C., Speer, T., Maack, C., Marx, N., Jankowski, J., Roma, L. P., & Noels, H. (2022). A systematic review and meta-analysis of murine models of uremic cardiomyopathy. Kidney International, 101(2), 256-273. https://doi.org/10.1016/j.kint.2021.10.025
    • Tullemans, B. M. E., Fernandez, D. I., Veninga, A., Baaten, C. C. F. M. J., Peters, L. J. F., Aarts, M. J. B., Eble, J. A., Campello, E., Spiezia, L., Simioni, P., van der Vorst, E. P. C., van der Meijden, P. E. J., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2022). Tyrosine Kinase Inhibitor Sunitinib Delays Platelet-Induced Coagulation: Additive Effects of Aspirin. Thrombosis and Haemostasis, 122(01), 92-104. https://doi.org/10.1055/s-0041-1730312
    • Heuschkel, M. A., Babler, A., Heyn, J., van der Vorst, E. P. C., Steenman, M., Gesper, M., Kappel, B. A., Magne, D., Gouëffic, Y., Kramann, R., Jahnen-Dechent, W., Marx, N., Quillard, T., & Goettsch, C. (2022). Distinct role of mitochondrial function and protein kinase C in intimal and medial calcification in vitro. Frontiers in cardiovascular medicine, 9, [959457]. https://doi.org/10.3389/fcvm.2022.959457
    • Basso, P. J., Rocha, C. R. R., Biessen, E. A. L., der Pluijm, I. V., Menck, C. F. M., & Câmara, N. O. S. (2022). Editorial: DNA repair and immune response. Frontiers in Immunology, 13, 1034689. https://doi.org/10.3389/fimmu.2022.1034689
    • Kip, A. M., Grootjans, J., Manca, M., Hadfoune, M., Boonen, B., Derikx, J. P. M., Biessen, E. A. L., Olde Damink, S. W. M., Dejong, C. H. C., Buurman, W. A., & Lenaerts, K. (2022). Temporal Transcript Profiling Identifies a Role for Unfolded Protein Stress in Human Gut Ischemia-Reperfusion Injury. Cellular and molecular gastroenterology and hepatology, 13(3), 681-694. https://doi.org/10.1016/j.jcmgh.2021.11.001
  • 2021
    • He, Y. Y., Xie, X. M., Zhang, H. D., Ye, J., Gencer, S., van der Vorst, E. P. C., Doering, Y., Weber, C., Pang, X. B., Jing, Z. C., Yan, Y., & Han, Z. Y. (2021). Corrigendum: Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension. Frontiers in Pharmacology, 12, [810178]. https://doi.org/10.3389/fphar.2021.810178
    • Jin, H., Mees, B., Biessen, E. A., & Sluimer, J. C. (2021). Transcriptional Sex Dimorphism in Human Atherosclerosis Relates to Plaque Type. Circulation Research, 129(12), 1175-1177. https://doi.org/10.1161/circresaha.121.320099
    • Biessen, E. A. L., & Van Berkel, T. J. C. (2021). N-Acetyl Galactosamine Targeting: Paving the Way for Clinical Application of Nucleotide Medicines in Cardiovascular Diseases. Arteriosclerosis Thrombosis and Vascular Biology, 41(12), 2855-2865. https://doi.org/10.1161/atvbaha.121.316290
    • Sundararaman, S. S., Peters, L. J. F., Nazir, S., Marquez, A. B., Bouma, J. E., Bayasgalan, S., Doering, Y., & van der Vorst, E. P. C. (2021). PCSK9 Imperceptibly Affects Chemokine Receptor Expression In Vitro and In Vivo. International Journal of Molecular Sciences, 22(23), [13026]. https://doi.org/10.3390/ijms222313026
    • Posma, J. J. N., & Sluimer, J. C. (2021). Pleiotropic, Cellular Effects of Rivaroxaban on Autophagy Explain Atheroprotective Effects. JACC: Basic to Translational Science, 6(12), 981-983. https://doi.org/10.1016/j.jacbts.2021.10.015
    • He, Y. Y., Xie, X. M., Zhang, H. D., Ye, J., Gencer, S., van der Vorst, E. P. C., Doering, Y., Weber, C., Pang, X. B., Jing, Z. C., Yan, Y., & Han, Z. Y. (2021). Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension. Frontiers in Pharmacology, 12, [753727]. https://doi.org/10.3389/fphar.2021.753727
    • Schumacher, D., Liehn, E. A., Singh, A., Curaj, A., Wijnands, E., Lira, S. A., Tacke, F., Jankowski, J., Biessen, E. A. L., & van der Vorst, E. P. C. (2021). CCR6 Deficiency Increases Infarct Size after Murine Acute Myocardial Infarction. Biomedicines, 9(11), [1532]. https://doi.org/10.3390/biomedicines9111532
    • Wang, S. J., Schianchi, F., Neumann, D., Wong, L. Y., Sun, A. M., van Nieuwenhoven, F. A., Zeegers, M. P., Strzelecka, A., Col, U., Glatz, J. F. C., Nabben, M., & Luiken, J. J. F. P. (2021). Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR-v-ATPase axis. Molecular Metabolism, 53, [101293]. https://doi.org/10.1016/j.molmet.2021.101293
    • Heeneman, S., de Jong, L. H., Dawson, L. J., Wilkinson, T. J., Ryan, A., Tait, G. R., Rice, N., Torre, D., Freeman, A., & van der Vleuten, C. P. M. (2021). Ottawa 2020 consensus statement for programmatic assessment-1. Agreement on the principles. Medical Teacher, 43(10), 1139-1148. https://doi.org/10.1080/0142159X.2021.1957088
    • Torre, D., Rice, N. E., Ryan, A., Bok, H., Dawson, L. J., Bierer, B., Wilkinson, T. J., Tait, G. R., Laughlin, T., Veerapen, K., Heeneman, S., Freeman, A., & van der Vleuten, C. (2021). Ottawa 2020 consensus statements for programmatic assessment 2: Implementation and practice. Medical Teacher, 43(10), 1149-1160. https://doi.org/10.1080/0142159X.2021.1956681
    • Wauters, L., Slaets, H., De Paepe, K., Ceulemans, M., Wetzels, S., Geboers, K., Toth, J., Thys, W., Dybajlo, R., Walgraeve, D., Biessen, E., Verbeke, K., Tack, J., Van de Wiele, T., Hellings, N., & Vanuytsel, T. (2021). Efficacy and safety of spore-forming probiotics in the treatment of functional dyspepsia: a pilot randomised, double-blind, placebo-controlled trial. The Lancet Gastroenterology and Hepatology, 6(10), 784-792. https://doi.org/10.1016/s2468-1253(21)00226-0
    • Bindels, E., van den Goor, M., Scherpbier, A., Lombarts, K., & Heeneman, S. (2021). Sharing Reflections on Multisource Feedback in a Peer Group Setting: Stimulating Physicians' Professional Performance and Development. Academic Medicine, 96(10), 1449-1456. https://doi.org/10.1097/acm.0000000000004142
    • Merlin, J., Ivanov, S., Dumont, A., Sergushichev, A., Gall, J., Stunault, M., Ayrault, M., Vaillant, N., Castiglione, A., Swain, A., Orange, F., Gallerand, A., Berton, T., Martin, J-C., Carobbio, S., Masson, J., Gaisler-Salomon, I., Maechler, P., Rayport, S., ... Yvan-Charvet, L. (2021). Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylation. Nature Metabolism, 3(10), 1313-1326. https://doi.org/10.1038/s42255-021-00471-y
    • Verheijden, M. J. H., Martens, H., & Heeneman, S. (2021). A dermatology E-learning programme is perceived as a valuable learning tool in postgraduate general practice training. International Journal of Medical Education, 12, 169-178. https://doi.org/10.5116/ijme.612f.3d6c
    • Waring, O. J., Skenteris, N. T., Biessen, E. A. L., & Donners, M. M. P. C. (2021). Two-faced Janus: The dual role of macrophages in atherosclerotic calcification. Cardiovascular Research. https://doi.org/10.1093/cvr/cvab301
    • van der Vorst, E. P. C., Pepe, M. A. A., Peters, L. J. F., Haberbosch, M., Jansen, Y., Naumann, R., Stathopoulos, G. T., Weber, C., & Bidzhekov, K. (2021). Correction to: Transcriptome signature of miRNA-26b KO mouse model suggests novel targets. BMC Genomic Data, 22(1), [36]. https://doi.org/10.1186/s12863-021-00990-3
    • Marquez, A. B., van der Vorst, E. P. C., & Maas, S. L. (2021). Key Chemokine Pathways in Atherosclerosis and Their Therapeutic Potential. Journal of Clinical Medicine, 10(17), [3825]. https://doi.org/10.3390/jcm10173825
    • Widowski, H., Ophelders, D. R. M. G., van Leeuwen, A. J. C. N., Nikkels, P. G. J., Severens-Rijvers, C. A. H., LaPointe, V. L. S., Cleutjens, J. P. M., Hütten, M. C., Kemp, M. W., Payne, M. S., Saito, M., Usuda, H., Newnham, J. P., Jobe, A. H., Kramer, B. W., Delhaas, T., Wolfs, T. G. A. M., & Reynaert, N. L. (2021). Chorioamnionitis induces changes in ovine pulmonary endogenous epithelial stem/progenitor cells in utero. Pediatric Research, 90(3), 549-558. https://doi.org/10.1038/s41390-020-01204-9
    • Saar-Kovrov, V., Zidek, W., Orth-Alampour, S., Fliser, D., Jankowski, V., Biessen, E. A. L., & Jankowski, J. (2021). Reduction of protein-bound uraemic toxins in plasma of chronic renal failure patients: A systematic review. Journal of Internal Medicine, 290(3), 499-526. https://doi.org/10.1111/joim.13248