• 2021
    • van Moort, I., Preijers, T., Bukkems, L. H., Hazendonk, H. C. A. M., van der Bom, J. G., Laros-van Gorkom, B. A. P., Beckers, E. A. M., Nieuwenhuizen, L., van der Meer, F. J. M., Ypma, P., Coppens, M., Fijnvandraat, K., Schutgens, R. E. G., Meijer, K., Leebeek, F. W. G., Mathot, R. A. A., Cnossen, M. H., & OPTI-CLOT Study Grp (2021). Perioperative pharmacokinetic-guided factor VIII concentrate dosing in haemophilia (OPTI-CLOT trial): an open-label, multicentre, randomised, controlled trial. The Lancet Haematology, 8(7), E492-E502. https://doi.org/10.1016/S2352-3026(21)00135-6
    • Bavalia, R., Bistervels, I. M., Boersma, W. G., Quere, I., Brisot, D., Falvo, N., Stephan, D., Couturaud, F., Schellong, S., Montaclair, K., Ghanima, W., ten Wolde, M., Coppens, M., Ferrari, E., Sanchez, O., Carroll, P., Kahn, S. R., Meijer, K., Birocchi, S., ... Hokusai Post-PE Study Investigator (2021). Quality of life in patients with pulmonary embolism treated with edoxaban versus warfarin. Research and practice in thrombosis and haemostasis, 5(5), Article e12566. https://doi.org/10.1002/rth2.12566
    • Driessen, R. G. H., Kiers, D., Schalkwijk, C. G., Scheijen, J. L. J. M., Gerretsen, J., Pickkers, P., van de Poll, M. C. G., van der Horst, I. C. C., Bergmans, D. C. J. J., Kox, M., & van Bussel, B. C. T. (2021). Systemic inflammation down-regulates glyoxalase-1 expression: an experimental study in healthy males. Bioscience Reports, 41(7), Article BSR20210954. https://doi.org/10.1042/BSR20210954
    • Evans, P., Wojta, J., Hoefer, I. E., Waltenberger, J., Guzik, T., Badimon, L., Weber, C., & Council of Basic Cardiovascular Science (2021). The year in basic vascular biology research: from mechanoreceptors and neutrophil extracellular traps to smartphone data and omics. Cardiovascular Research, 117(8), 1814-1822. https://doi.org/10.1093/cvr/cvab105
    • Camps, E. C., van Lith, S. A. M., Frielink, C., Lankhof, J., Dijkgraaf, I., Gotthardt, M., & Brock, R. (2021). CPPs to the Test: Effects on Binding, Uptake and Biodistribution of a Tumor Targeting Nanobody. Pharmaceuticals, 14(7), Article 602. https://doi.org/10.3390/ph14070602
    • Petersohn, S., Grimm, S. E., Ramaekers, B. L. T., ten Cate-Hoek, A. J., & Joore, M. A. (2021). Exploring the Feasibility of Comprehensive Uncertainty Assessment in Health Economic Modeling: A Case Study. Value in Health, 24(7), 983-994. https://doi.org/10.1016/j.jval.2021.01.004
    • Castoldi, E. (2021). F5-Atlanta: Factor V-short strikes again. Journal of Thrombosis and Haemostasis, 19(7), 1638-1640. https://doi.org/10.1111/jth.15351
    • Denisov, S. S., Ippel, J. H., Castoldi, E., Mans, B. J., Hackeng, T. M., & Dijkgraaf, I. (2021). Molecular basis of anticoagulant and anticomplement activity of the tick salivary protein Salp14 and its homologs. Journal of Biological Chemistry, 297(1), Article 100865. https://doi.org/10.1016/j.jbc.2021.100865
    • Herfs, L., Swieringa, F., Jooss, N., Kozlowski, M., Heubel-Moenen, F. C. J., van Oerle, R., Machiels, P., Henskens, Y., & Heemskerk, J. W. M. (2021). Multiparameter microfluidics assay of thrombus formation reveals increased sensitivity to contraction and antiplatelet agents at physiological temperature. Thrombosis Research, 203, 46-56. https://doi.org/10.1016/j.thromres.2021.04.014
    • Liu, X., Arfman, T., Wichapong, K., Reutelingsperger, C. P. M., Voorberg, J., & Nicolaes, G. A. F. (2021). PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune-mediated disease. Journal of Thrombosis and Haemostasis, 19(7), 1607-1617. https://doi.org/10.1111/jth.15313
    • Baaten, C. C. F. M. J., Sternkopf, M., Henning, T., Marx, N., Jankowski, J., & Noels, H. (2021). Platelet Function in CKD: A Systematic Review and Meta-Analysis. Journal of the American Society of Nephrology, 32(7), 1583-1598. https://doi.org/10.1681/asn.2020101440
    • Dickhout, A., Kaczor, D. M., Heinzmann, A. C. A., Brouns, S. L. N., Heemskerk, J. W. M., van Zandvoort, M. A. M. J., & Koenen, R. R. (2021). Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells. International journal of molecular sciences, 22(14), Article 7332. https://doi.org/10.3390/ijms22147332
    • Stals, M. A. M., Kaptein, F. H. J., Bemelmans, R. H. H., van Bemmel, T., Boukema, I. C., Braeken, D. C. W., Braken, S. J. E., Bresser, C., Cate, H. T., Deenstra, D. D., Dooren, Y. P. A. V., Faber, L. M., Grootenboers, M. J. J. H., Haan, L. R. D., Haazer, C., Sol, A. I. D., Kelliher, S., Koster, T., Kroft, L. J. M., ... Dutch COVID & Thrombosis Coalition (DCTC) (2021). Ruling out Pulmonary Embolism in Patients with (Suspected) COVID-19-A Prospective Cohort Study. TH open : companion journal to thrombosis and haemostasis, 5(3), e387-e399. https://doi.org/10.1055/s-0041-1735155
    • Maag, A., Sharma, P., Schuijt, T. J., Kopatz, W. F., Kruijswijk, D., Marquart, J. A., van Der Poll, T., Hackeng, T. M., Nicolaes, G. A. F., Meijers, J. C. M., Bos, M. H. A., & van 't Veer, C. (2021). Structure-function of anticoagulant TIX-5, the inhibitor of factor Xa-mediated FV activation. Journal of Thrombosis and Haemostasis, 19(7), 1697-1708. https://doi.org/10.1111/jth.15329
    • Hisada, Y., Moser, B., Kawano, T., Revenko, A. S., Crosby, J. R., Spronk, H. M., & Mackman, N. (2021). The Intrinsic Pathway does not Contribute to Activation of Coagulation in Mice Bearing Human Pancreatic Tumors Expressing Tissue Factor. Thrombosis and Haemostasis, 121(07), 967-970. https://doi.org/10.1055/s-0040-1722193
    • van der Vorst, E. P. C., Pepe, M. A. A., Peters, L. J. F., Haberbosch, M., Jansen, Y., Nauman, R., Stathopoulos, G. T., Weber, C., & Bidzhekov, K. (2021). Transcriptome signature of miRNA-26b KO mouse model suggests novel targets. BMC Genomic Data, 22(1), Article 23. https://doi.org/10.1186/s12863-021-00976-1
    • Schol, P. B. B., de Lange, N. M., Woiski, M. D., Langenveld, J., Smits, L. J. M., Wassen, M. M., Henskens, Y. M., & Scheepers, H. C. J. (2021). Restrictive versus liberal fluid resuscitation strategy, influence on blood loss and hemostatic parameters in mild obstetric hemorrhage: An open-label randomized controlled trial. (REFILL study). PLOS ONE, 16(6), Article e0253765. https://doi.org/10.1371/journal.pone.0253765
    • van Doorn, W. P. T. M., Foreman, Y. D., Schaper, N. C., Savelberg, H. H. C. M., Koster, A., van der Kallen, C. J. H., Wesselius, A., Schram, M. T., Henry, R. M. A., Dagnelie, P. C., de Galan, B. E., Bekers, O., Stehouwer, C. D. A., Meex, S. J. R., & Brouwers, M. C. G. J. (2021). Machine learning-based glucose prediction with use of continuous glucose and physical activity monitoring data: The Maastricht Study. PLOS ONE, 16(6), Article e0253125. https://doi.org/10.1371/journal.pone.0253125
    • Baidildinova, G., Nagy, M., Jurk, K., Wild, P. S., ten Cate, H., & van der Meijden, P. E. J. (2021). Soluble Platelet Release Factors as Biomarkers for Cardiovascular Disease. Frontiers in Cardiovascular Medicine, 8, Article 684920. https://doi.org/10.3389/fcvm.2021.684920
    • Lacy, M., Buerger, C., Shami, A., Ahmadsei, M., Winkels, H., Nitz, K., van Tiel, C. M., Seijkens, T. T. P., Kusters, P. J. H., Karshovka, E., Prange, K. H. M., Wu, Y., Brouns, S. L. N., Unterlugauer, S., Kuijpers, M. J. E., Reiche, M. E., Steffens, S., Edsfeldt, A., Megens, R. T. A., ... Lutgens, E. (2021). Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease. Nature Communications, 12(1), Article 3754. https://doi.org/10.1038/s41467-021-23909-z
    • Dahlen, B., Mueller, F., Troebs, S.-O., Heidorn, M. W., Schulz, A., Arnold, N., Hermanns, M. I., Schwuchow-Thonke, S., Prochaska, J. H., Gori, T., ten Cate, H., Lackner, K. J., Muenzel, T., Wild, P. S., & Panova-Noeva, M. (2021). Sex-Specific Relationship Between Parathyroid Hormone and Platelet Indices in Phenotypes of Heart Failure - Results From the MyoVasc Study. Frontiers in Cardiovascular Medicine, 8, Article 682521. https://doi.org/10.3389/fcvm.2021.682521
    • ten Berg, J., Sibbing, D., Rocca, B., Van Belle, E., Chevalier, B., Collet, J. P., Dudek, D., Gilard, M., Gorog, D. A., Grapsa, J., Grove, E. L., Lancellotti, P., Petronio, A. S., Rubboli, A., Torracca, L., Vilahur, G., Witkowski, A., & Mehilli, J. (2021). Management of antithrombotic therapy in patients undergoing transcatheter aortic valve implantation: a consensus document of the ESC Working Group on Thrombosis and the European Association of Percutaneous Cardiovascular Interventions (EAPCI), in collaboration with the ESC Council on Valvular Heart Disease. European Heart Journal, 42(23), 2265-2269. https://doi.org/10.1093/eurheartj/ehab196
    • Selvarajah, A., Tavenier, A. H., Bor, W. L., Houben, A. J. H. M., Rasoul, S., Kaplan, E., Teeuwen, K., Hofma, S. H., Lipsic, E., Amoroso, G., van Leeuwen, M. A. H., ten Berg, J. M., van 't Hof, A. W. J., & Hermanides, R. S. (2021). Feasibility and safety of cangrelor in patients with suboptimal P2Y(12) inhibition undergoing percutaneous coronary intervention: rationale of the Dutch Cangrelor Registry. BMC Cardiovascular disorders, 21(1), Article 292. https://doi.org/10.1186/s12872-021-02093-4
    • Huang, J., Swieringa, F., Solari, F. A., Provenzale, I., Grassi, L., De Simone, I., Baaten, C. C. F. M. J., Cavill, R., Sickmann, A., Frontini, M., & Heemskerk, J. W. M. (2021). Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions. Scientific Reports, 11(1), Article 12358. https://doi.org/10.1038/s41598-021-91661-x
    • Cao, J., Balluff, B., Arts, M., Dubois, L. J., van Loon, L. J. C., Hackeng, T. M., van Eijk, H. M. H., Eijkel, G., Heij, L. R., Soons, Z., Olde Damink, S. W. M., & Heeren, R. M. A. (2021). Mass spectrometry imaging of L-[ring-13C6]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma. Cancer & Metabolism, 9(1), Article 26. https://doi.org/10.1186/s40170-021-00262-9
    • Ford, D. J., Duggan, N. M., Fry, S. E., Ripoll-Rozada, J., Agten, S. M., Liu, W., Corcilius, L., Hackeng, T. M., van Oerle, R., Spronk, H. M. H., Ashhurst, A. S., Mini Sasi, V., Kaczmarski, J. A., Jackson, C. J., Pereira, P. J. B., Passioura, T., Suga, H., & Payne, R. J. (2021). Potent Cyclic Peptide Inhibitors of FXIIa Discovered by mRNA Display with Genetic Code Reprogramming. Journal of Medicinal Chemistry, 64(11), 7853-7876. https://doi.org/10.1021/acs.jmedchem.1c00651
    • de Breet, C. P. D. M., Zwaveling, S., Vries, M. J. A., van Oerle, R. G., Henskens, Y. M. C., Van't Hof, A. W. J., van der Meijden, P. E. J., Veenstra, L., ten Cate, H., & Olie, R. H. (2021). Thrombin Generation as a Method to Identify the Risk of Bleeding in High Clinical-Risk Patients Using Dual Antiplatelet Therapy. Frontiers in Cardiovascular Medicine, 8, Article 679934. https://doi.org/10.3389/fcvm.2021.679934
    • Notten, P., de Smet, A. A. E. A., Tick, L. W., van de Poel, M. H. W., Wikkeling, O. R. M., Vleming, L.-J., Koster, A., Jie, K.-S. G., Jacobs, E. M. G., Ebben, H. P., Coppens, M., ten Cate, H., Wittens, C. H. A., & ten Cate-Hoek, A. J. (2021). CAVA (Ultrasound-Accelerated Catheter-Directed Thrombolysis on Preventing Post-Thrombotic Syndrome) Trial: Long-Term Follow-Up Results. Journal of the American Heart Association, 10(11), Article e018973. https://doi.org/10.1161/JAHA.120.018973
    • Mahmoodi, B. K., Eriksson, N., Vos, G. J. A., Meijer, K., Siegbahn, A., James, S., Wallentin, L., & ten Berg, J. M. (2021). Factor V Leiden Does Not Modify the Phenotype of Acute Coronary Syndrome or the Extent of Myocardial Necrosis. Journal of the American Heart Association, 10(11), Article e020025. https://doi.org/10.1161/JAHA.120.020025
    • Braeken, D. C. W., Essig, A., Panning, M., Hoerster, R., Nawrocki, M., Dalhoff, K., Suttorp, N., Welte, T., Pletz, M. W., Witzenrath, M., Rohde, G. G. U., Rupp, J., & CAPNETZ Study Grp (2021). Shift in bacterial etiology from the CAPNETZ cohort in patients with community-acquired pneumonia: data over more than a decade. Infection, 49(3), 533-537. https://doi.org/10.1007/s15010-021-01605-w
    • Driessen, R. G. H., Latten, B. G. H., Bergmans, D. C. J. J., Hulsewe, R. P. M. G., Holtkamp, J. W. M., van der Horst, I. C. C., Kubat, B., & Schnabel, R. M. (2021). Clinical diagnoses vs. autopsy findings in early deceased septic patients in the intensive care: a retrospective cohort study. Virchows Archiv, 478(6), 1173-1178. https://doi.org/10.1007/s00428-020-02984-5
    • Wasserloos, A., Thomassen, M. C. L. G. D., Costa, S. D., Zenclussen, A., Tchaikovski, V. E., Hackeng, T. M., Stickeler, E., & Tchaikovski, S. N. (2021). Effect of blood loss during caesarean section on coagulation parameters. Thrombosis Research, 202, 84-89. https://doi.org/10.1016/j.thromres.2021.03.010
    • Iding, A. F. J., Witten, A., Isaacs, A., Castoldi, E., ten Cate, H., Stoll, M., & ten Cate-Hoek, A. J. (2021). Leukocyte gene expression in post-thrombotic syndrome. Thrombosis Research, 202, 40-42. https://doi.org/10.1016/j.thromres.2021.03.007
    • Sabrkhany, S., Kuijpers, M. J. E., Egbrink, M. G. A. O., & Griffioen, A. W. (2021). Platelets as messengers of early-stage cancer. Cancer and Metastasis Reviews, 40(2), 563-573. https://doi.org/10.1007/s10555-021-09956-4
    • Donkel, S. J., Pater, K., Leebeek, F. W. G., Dippel, D. W. J., Ten Cate, H., & de Maat, M. P. M. (2021). Thrombin generation is associated with ischemic stroke at a young age. Thrombosis Research, 202, 139-144. https://doi.org/10.1016/j.thromres.2021.03.028
    • Mulder, M. M. G., Brandts, LI., Brüggemann, R. A. G., Koelmann, M., Streng, A. S., Olie, R. H., Gietema, H. A., Spronk, H. M. H., van der Horst, I. C. C., Sels, J.-W. E. M., Wildberger, J. E., van Kuijk, S. M. J., Schnabel, R. M., Ten Cate, H., Henskens, Y. M. C., & van Bussel, B. C. T. (2021). Serial markers of coagulation and inflammation and the occurrence of clinical pulmonary thromboembolism in mechanically ventilated patients with SARS-CoV-2 infection; the prospective Maastricht intensive care COVID cohort. Thrombosis Journal, 19(1), Article 35. https://doi.org/10.1186/s12959-021-00286-7
    • Egea, V., Kessenbrock, K., Lawson, D., Bartelt, A., Weber, C., & Ries, C. (2021). Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release. Cell Death & Disease, 12(6), Article 516. https://doi.org/10.1038/s41419-021-03789-3
    • Munnix, I. C. A., Van Oerle, R., Verhezen, P., Kuijper, P., Hackeng, C. M., Hopman-Kerkhoff, H. I. J., Hudig, F., Van De Kerkhof, D., Leyte, A., De Maat, M. P. M., Elferink, R. F. M. O., Ruinennans-Koerts, J., Schoorl, M., Slomp, J., Soons, H., Stroobants, A., Van Wijk, E., & Henskens, Y. M. C. (2021). Harmonizing light transmission aggregometry in the Netherlands by implementation of the SSC-ISTH guideline. Platelets, 32(4), 516-523. https://doi.org/10.1080/09537104.2020.1771549
    • Hulshof, A. M., Vries, M., Verhezen, P., Wetzels, R., Haartmans, M., Olie, R., Ten Cate, H., & Henskens, Y. (2021). The Influence of Prostaglandin E1 and Use of Inhibitor Percentage on the Correlation between the Multiplate and VerifyNow in Patients on Dual Antiplatelet Therapy. Platelets, 32(4), 463-468. https://doi.org/10.1080/09537104.2020.1754378
    • Sundararaman, S. S., Peters, L. J. F., Jansen, Y., Gencer, S., Yan, Y., Nazir, S., Marquez, A. B., Kahles, F., Lehrke, M., Biessen, E. A. L., Jankowski, J., Weber, C., Doering, Y., & van der Vorst, E. P. C. (2021). Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe(-/-) mice. Scientific Reports, 11(1), Article 10409. https://doi.org/10.1038/s41598-021-89893-y
    • Zweiker, D., Manninger, M., Sieghartsleitner, R., Ebner, J., Pratl, B., Bisping, E., Lercher, P., von Lewinski, D., Riedlbauer, R., Rohrer, U., Spronk, H. M. H., Zirlik, A., Schotten, U., & Scherr, D. (2021). No antiarrhythmic effect of direct oral anticoagulants versus vitamin K antagonists in paroxysmal atrial fibrillation patients undergoing catheter ablation. International Journal of Cardiology, 331, 106-108. https://doi.org/10.1016/j.ijcard.2021.01.003
    • Ercig, B., Gomes Graca, N. A., Kangro, K., Arfman, T., Wichapong, K., Hrdinova, J., Kaijen, P., van Alphen, F., van den Biggelaar, M., Vanhoorelbeke, K., Veyradier, A., Coppo, P., Reutelingsperger, C., Nicolaes, G. A. F., Männik, A., & Voorberg, J. (2021). N-glycan mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP. Blood, 137(19), 2694-2698. https://doi.org/10.1182/blood.2020007972
    • Nagy, M., Fazaeli, S., van Oerle, R., Ten Cate, H., Schemmann, M., Sherry, J., Kelleher, G., & Spronk, H. M. H. (2021). Evaluation of the analytical performance of the PC100 platelet counter. Thrombosis Journal, 19(1), Article 29. https://doi.org/10.1186/s12959-021-00283-w
    • ten Cate, H. (2021). Thrombosis: Grand Challenges Ahead!Frontiers in Cardiovascular Medicine, 8, Article 637005. https://doi.org/10.3389/fcvm.2021.637005
    • Hermann, J., Noels, H., Theelen, W., Lellig, M., Orth-Alampour, S., Boor, P., Jankowski, V., & Jankowski, J. (2021). Correction to: Sample preparation of formalin-fixed paraffin-embedded tissue sections for MALDI-mass spectrometry imaging. Analytical and Bioanalytical Chemistry, 413(11), 3141-3141. https://doi.org/10.1007/s00216-021-03276-w
    • Bavalia, R., Veenhuizen, J. E., Hengeveld, R. C. C., Braeken, D., Gulpen, A. J. W., Ten Cate, H., Middeldorp, S., Henskens, Y. M. C., Hutten, B. A., Coppens, M., & Stroobants, A. K. (2021). Direct oral anticoagulant blood level monitoring in daily practice. Thrombosis Update, 3, Article 100049. https://doi.org/10.1016/j.tru.2021.100049
    • Gresele, P., Falcinelli, E., Bury, L., Pecci, A., Alessi, M. C., Borhany, M., Heller, P. G., Santoro, C., Cid, A. R., Orsini, S., Fontana, P., De Candia, E., Podda, G., Kannan, M., Jurk, K., Castaman, G., Falaise, C., Guglielmini, G., Noris, P., ... BAT-VAL Study Investigators (2021). The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology. Journal of Thrombosis and Haemostasis, 19(5), 1364-1371. https://doi.org/10.1111/jth.15263
    • Liu, X., Wichapong, K., Lamers, S., Reutelingsperger, C. P. M., & Nicolaes, G. A. F. (2021). Autocitrullination of PAD4 does not alter its enzymatic activity: In vitro and in silico studies. International Journal of Biochemistry & Cell Biology, 134, Article 105938. https://doi.org/10.1016/j.biocel.2021.105938
    • Pluymaekers, N. A. H. A., Dudink, E. A. M. P., Weijs, B., Vernooy, K., Hartgerink, D. E. J., Jacobs, J. S., Erkuner, O., Marcks, N. G. H. M., van Cauteren, Y. J. M., Dinh, T., ter Bekke, R. M. A., Sels, J. E. M. W., Delnoij, T. S. R., Geyik, Z., Driessen, R. G. H., Linz, D. K., den Uijl, D. W., Crijns, H. J. G. M., & Luermans, J. G. L. M. (2021). Clinical determinants of early spontaneous conversion to sinus rhythm in patients with atrial fibrillation. Netherlands Heart Journal, 29(5), 255-261. https://doi.org/10.1007/s12471-020-01528-5
    • ten Cate, H. (2021). Colorectal cancer and cardiovascular disease: A thrombo-inflammatory link?European journal of internal medicine, 87, 15-17. https://doi.org/10.1016/j.ejim.2021.03.019