• 2010
    • Liu, Z., Lin, L., Yuan, C., Nicolaes, G. A. F., Chen, L., Meehan, E. J., Furie, B., Furie, B. C., & Huang, M. (2010). Trp(2313)-His(2315) of Factor VIII C2 Domain Is Involved in Membrane Binding STRUCTURE OF A COMPLEX BETWEEN THE C2 DOMAIN AND AN INHIBITOR OF MEMBRANE BINDING. Journal of Biological Chemistry, 285(12), 8824-8829. https://doi.org/10.1074/jbc.M109.080168
    • Castoldi, E., & Rosing, J. (2010). APC resistance: biological basis and acquired influences. Journal of Thrombosis and Haemostasis, 8(3), 445-453. https://doi.org/10.1111/j.1538-7836.2009.03711.x
    • Koenen, R. R., & Weber, C. (2010). Manipulating the chemokine system: Therapeutic perspectives for atherosclerosis. Current Opinion in Investigational Drugs, 11(3), 265-272.
    • Koenen, R. R., & Weber, C. (2010). Platelet-Derived Chemokines in Vascular Remodeling and Atherosclerosis. Seminars in Thrombosis and Hemostasis, 36(2), 163-169. https://doi.org/10.1055/s-0030-1251500
    • Wijnen, P. A., Nelemans, P. J., Verschakelen, J. A., Bekers, O., Voorter, C. E., & Drent, M. (2010). The role of tumor necrosis factor alpha G-308A polymorphisms in the course of pulmonary sarcoidosis.Tissue Antigens, 75(3), 262-268. https://doi.org/10.1111/j.1399-0039.2009.01437.x
    • Bouman, H. J., Parlak, E., van Werkum, J. W., Breet, N. J., ten Cate, H., Hackeng, C. M., Ten Berg, J. M., & Taubert, D. (2010). Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel. Journal of Thrombosis and Haemostasis, 8(3), 482-488. https://doi.org/10.1111/j.1538-7836.2009.03733.x
    • Oostendorp, M., Douma, K., Wagenaar, A., Slenter, J. M. G. M., Hackeng, T. M., van Zandvoort, M. A. M. J., Post, M. J., & Backes, W. H. (2010). Molecular Magnetic Resonance Imaging of Myocardial Angiogenesis After Acute Myocardial Infarction. Circulation, 121(6), 775-U85. https://doi.org/10.1161/CIRCULATIONAHA.109.889451
    • de Kruif, M. D., Limper, M., Gerritsen, H., Spek, C. A., Brandjes, D. P. M., ten Cate, H., Bossuyt, P. M., Reitsma, P. H., & van Gorp, E. C. M. (2010). Additional value of procalcitonin for diagnosis of infection in patients with fever at the emergency department. Critical Care Medicine, 38(2), 457-463. https://doi.org/10.1097/CCM.0b013e3181b9ec33
    • Castoldi, E., Simioni, P., Tormene, D., Rosing, J., & Hackeng, T. M. (2010). Hereditary and acquired protein S deficiencies are associated with low TFPI levels in plasma. Journal of Thrombosis and Haemostasis, 8(2), 294-300. https://doi.org/10.1111/j.1538-7836.2009.03712.x
    • Schols, S. E. M., Lance, M. D., Feijge, M. A. H., Damoiseaux, J., Marcus, M. A., Hamulyak, K., ten Cate, H., Heemskerk, J. W. M., & van Pampus, E. C. M. (2010). Impaired thrombin generation and fibrin clot formation in patients with dilutional coagulopathy during major surgery. Thrombosis and Haemostasis, 103(2), 318-328. https://doi.org/10.1160/TH09-06-0396
    • de Kruif, M. D., Limper, M., Sierhuis, K., Wagenaar, J. F. P., Spek, C. A., Garlanda, C., Cotena, A., Mantovani, A., ten Cate, H., Reitsma, P. H., & van Gorp, E. C. M. (2010). PTX3 predicts severe disease in febrile patients at the emergency department. Journal of Infection, 60(2), 122-127. https://doi.org/10.1016/j.jinf.2009.11.010
    • Engelen, L., Ferreira, I., Gaens, K. H. J., Henry, R. M. A., Dekker, J. M., Nijpels, G., Heine, R. J., 't Hart, L. M., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Blaak, E. E., Feskens, E. J. M., ten Cate, H., Stehouwer, C. D. A., & Schalkwijk, C. G. (2010). The association between the-374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies. Journal of Hypertension, 28(2), 285-293. https://doi.org/10.1097/HJH.0b013e3283330931
    • Koenen, R. R., & Weber, C. (2010). Therapeutic targeting of chemokine interactions in atherosclerosis. Nature Reviews Drug Discovery, 9(2), 141-153. https://doi.org/10.1038/nrd3048
    • Duckers, C., Simioni, P., Spiezia, L., Radu, C. M., Dabrilli, P., Gavasso, S., Rosing, J., & Castoldi, E. (2010). Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms. Blood, 115(4), 879-886. https://doi.org/10.1182/blood-2009-08-237719
    • Wijnen, P. A. H. M., Bekers, O., & Drent, M. (2010). 'Drug'-induced pneumonitis associated with CYP and VKORC1 variants.The Bulletin of contemporary clinical medicine, 3, 15-17. https://doi.org/10.20969/VSKM.2010.3(4).15-17
    • Jacobs, L. H., van de Kerkhof, J. J., Mingels, A. M., Lima Passos, V., Kleijnen, V. W., Mazairac, A. H., van der Sande, F. M., Wodzig, W. K., Konings, C. J., Leunissen, K. M., van Dieijen-Visser, M. P., & Kooman, J. P. (2010). Inflammation, overhydration and cardiac biomarkers in haemodialysis patients: a longitudinal study.Nephrology Dialysis Transplantation, 25(1), 243-248. https://doi.org/10.1093/ndt/gfp417
    • Lobbes, M. B., Kooi, M. E., Lutgens, E., Lima Passos, V., Braat, S. H. J. G., Rousch, M. J. M., ten Cate, H., van Engelshoven, J. M., Daemen, M. J., & Heeneman, S. (2010). Leukocyte counts, myeloperoxidase, and pregnancy-associated plasma protein a as biomarkers for cardiovascular disease: towards a multi-biomarker approach.International Journal of Vascular Medicine, 2010(726207). https://doi.org/10.1155/2010/726207
    • Wijnen, P. A., Bekers, O., van Dieijen-Visser, M. P., & Drent, M. (2010). Pharmacogenetic testing after a simple DNA isolation method.The Bulletin of contemporary clinical medicine, 3, 9-14. https://doi.org/10.20969/VSKM.2010.3(4).9-14
    • Wisse, W., Rookhuizen, M. B., de Kruif, M. D., van Rossum, J., Jordans, I., ten Cate, H., van Loon, L. J. C., & Meesters, E. W. (2010). Prescription of physical activity is not sufficient to change sedentary behavior and improve glycemic control in type 2 diabetes patients.Diabetes Research and Clinical Practice, 88(2), E10-13. https://doi.org/10.1016/j.diabres.2010.01.015
    • Wijnen, P. A., Linssen, C. F., Haenen, G. R., Bekers, O., & Drent, M. (2010). Variant VKORC1 and CYP2C9 Alleles in Patients with Diffuse Alveolar Hemorrhage Caused by Oral Anticoagulants. Molecular Diagnosis & Therapy, 14(1), 23-30. https://doi.org/10.1007/BF03256350
    • Segers, O., van Oerle, R., ten Cate, H., Rosing, J., & Castoldi, E. (2010). Thrombin generation as an intermediate phenotype for venous thrombosis A proof-of-concept study. Thrombosis and Haemostasis, 103(1), 114-122. https://doi.org/10.1160/TH09-06-0356
    • Megens, R. T. A., Reitsma, S., Prinzen, L., Egbrink, M. G. A. O., Engels, W., Leenders, P. J. A., Brunenberg, E. J. L., Reesink, K. D., Janssen, B. J. A., Romeny, B. M. T. H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2010). In vivo high-resolution structural imaging of large arteries in small rodents using two-photon laser scanning microscopy. Journal of Biomedical Optics, 15(1), 10. https://doi.org/10.1117/1.3281672
    • Van de Vijver, P., Suylen, D. P., Dirksen, A., Dawson, P. E., & Hackeng, T. M. (2010). N-epsilon-(Thiaprolyl)-lysine as a Handle for Site-Specific Protein Conjugation. Biopolymers, 94(4), 465-474. https://doi.org/10.1002/bip.21485
    • Oostendorp, M., Douma, K., Hackeng, T. M., van Zandvoort, M. A. M. J., Post, M. J., & Backes, W. H. (2010). Pharmacokinetics of contrast agents targeted to the tumor vasculature in molecular magnetic resonance imaging. Contrast Media & Molecular Imaging, 5(1), 9-17. https://doi.org/10.1002/cmmi.361
    • Senen, K., Topal, E., Kilinc, E., ten Cate, H., Tek, I., Karakoc, Y., & Yetkin, E. (2010). Plasma viscosity and mean platelet volume in patients undergoing coronary angiography. Clinical Hemorheology and Microcirculation, 44(1), 35-41. https://doi.org/10.3233/CH-2010-1249
  • 2009
    • Klomp, C. M., ten Cate, H., Stehouwer, C. D., & Schaper, N. C. (2009). Acetylsalicylzuur bij patienten met diabetes mellitus: niet voor primaire, wel voor secundaire preventie van hart-vaatziekten. Nederlands Tijdschrift voor Geneeskunde, 153, A109. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19785798
    • Wijnen, P. A., Limantoro, I., Drent, M., Bekers, O., Kuijpers, P. M., & Koek, G. H. (2009). Depressive effect of an antidepressant: therapeutic failure of venlafaxine in a case lacking CYP2D6 activity. Annals of Clinical Biochemistry, 46(Pt 6), 527-30. https://doi.org/10.1258/acb.2009.009003
    • Wolfs, J. L., Comfurius, P., Bekers, O., Zwaal, R. F., Balasubramanian, K., Schroit, A. J., Lindhout, T., & Bevers, E. M. (2009). Direct inhibition of phospholipid scrambling activity in erythrocytes by potassium ions. Cellular and Molecular Life Sciences, 66(2), 314-23. https://doi.org/10.1007/s00018-008-8566-4
    • Lind, J. S., Postmus, P. E., Heideman, D. A., Thunnissen, E. B., Bekers, O., & Smit, E. F. (2009). Dramatic response to low-dose erlotinib of epidermal growth factor receptor mutation-positive recurrent non-small cell lung cancer after severe cutaneous toxicity. Journal of Thoracic Oncology, 4(12), 1585-6. https://doi.org/10.1097/JTO.0b013e3181bbb2b9
    • Jacobs, L. H., van de Kerkhof, J., Mingels, A. M., Kleijnen, V. W., van der Sande, F. M., Wodzig, W. K., Kooman, J. P., & van Dieijen-Visser, M. P. (2009). Haemodialysis patients longitudinally assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and cardiac troponin I assays.Annals of Clinical Biochemistry, 46(Pt 4), 283-290. https://doi.org/10.1258/acb.2009.008197
    • Miserus, R. J., Herias, M. V., Prinzen, L., Lobbes, M. B., van Suylen, R. J., Dirksen, A., Hackeng, T. M., Heemskerk, J. W., van Engelshoven, J. M., Daemen, M. J. A. P., van Zandvoort, M. A. M. J., Heeneman, S., & Kooi, M. E. (2009). Molecular MRI of early thrombus formation using a bimodal alpha2-antiplasmin-based contrast agent. JACC-Cardiovascular Imaging, 2(8), 987-96. https://doi.org/10.1016/j.jcmg.2009.03.015
    • Wijnen, P. A. H. M., Drent, M., van Dieijen-Visser, M. P., & Bekers, O. (2009). Pharmacogenetic testing after a simple DNA isolation method on buccal swab samples. Pharmacogenomics, 10(6), 983-7. https://doi.org/10.2217/pgs.09.4
    • Miserus, R., Dirksen, A., Suylen, D. P., Herias, V., Prinzen, L., van Zandvoort, M. A. M. J., Kooi, M. E., Dawson, P., Heeneman, S., Daemen, M. J., & Hackeng, T. M. (2009). Total Chemical Synthesis of Bimodal-Labeled Rantes as a Pet/Tplsm Probe for in Vivo Molecular Imaging of Atherosclerotic Plaque Instability. Biopolymers, 92(4), 376-376. http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ResearchSoft&SrcApp=EndNote&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000266753100412
  • 2008
    • Vanschoonbeek, K., Wouters, K., van der Meijden, P. E., van Gorp, P. J. J., Feijge, M. A., Herfs, M., Schurgers, L. J., Hofker, M. H., de Maat, M. P., & Heemskerk, J. W. (2008). Anticoagulant effect of dietary fish oil in hyperlipidemia: a study of hepatic gene expression in APOE2 knock-in mice.Arteriosclerosis Thrombosis and Vascular Biology, 28(11), 2023-2029. https://doi.org/10.1161/ATVBAHA.107.156992
    • Linssen, C. F. M., Bekers, O., Drent, M., & Jacobs, J. A. (2008). C-reactive protein and procalcitonin concentrations in bronchoalveolar lavage fluid as a predictor of ventilator-associated pneumonia. Annals of Clinical Biochemistry, 45(Pt 3), 293-8. https://doi.org/10.1258/acb.2007.007133
    • van Schaik, R. H. N., Grandia, L., de Goede, A., Bet, P. M., Bekers, O., Guchelaar, H. J., Goldschmidt, H. M. J., Meijer, M. M. C., Mulder, H., van der Weide, J., & Deneer, V. H. M. (2008). CYP2D6 genotype `1-0' ingedeeld als intermediaire metaboliseerder.Nederlands tijdschrift voor klinische chemie en laboratoriumgeneeskunde, 33(1), 52.
    • Wijnen, P. A. H. M., op den Buijsch, R. A., Cheung, S. C., van der Heijden, J., Hoogtanders, K., Stolk, L. M. L., van Dieijen-Visser, M., Neef, C. K., Drent, M., & Bekers, O. (2008). Genotyping with a dried blood spot method: a useful technique for application in pharmacogenetics. Clinica Chimica Acta, 388(1-2), 189-91. https://doi.org/10.1016/j.cca.2007.10.001
    • Wijnen, P. A. H. M., Drent, M., Nelemans, P. J., Kuijpers, P. M., Koek, G. H., Neef, C. K., Haenen, G. R., & Bekers, O. (2008). Role of cytochrome p450 polymorphisms in the development of pulmonary drug toxicity: a case-control study in the Netherlands. Drug Safety, 31(12), 1125-34. https://doi.org/10.2165/0002018-200831120-00008
    • Ramakers, I. H. G. B., Visser, P. J., Aalten, P., Bekers, O., Sleegers, K., van Broeckhoven, C. L., Jolles, J., & Verhey, F. R. (2008). The association between APOE genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and Alzheimer pathology. Dementia and Geriatric Cognitive Disorders, 26(2), 101-8. https://doi.org/10.1159/000144072
    • Cranenburg, E. C., Vermeer, C., Koos, R., Boumans, M. L., Hackeng, T. M., Bouwman, F. G., Kwaijtaal, M., Brandenburg, V. M., Ketteler, M., & Schurgers, L. J. (2008). The circulating inactive form of matrix Gla Protein (ucMGP) as a biomarker for cardiovascular calcification. Journal of Vascular Research, 45(5), 427-36. https://doi.org/10.1159/000124863
    • Meex, S. J., van Vliet-Ostaptchouk, J. V., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Schalkwijk, C. G., Feskens, E. J. M., Blaak, E. E., Wijmenga, C., Hofker, M. H., Stehouwer, C. D., & de Bruin, T. W. (2008). Upstream transcription factor 1 (USF1) in risk of type 2 diabetes: Association study in 2000 Dutch Caucasians. Molecular Genetics and Metabolism, 94(3), 352-355. https://doi.org/10.1016/j.ymgme.2008.03.011
  • 2007
    • Meex, S. J., van Greevenbroek, M. M. J., Ayoubi, T. A., Vlietinck, R., van Vliet-Ostaptchouk, J. V., Hofker, M. H., Vermeulen, V. M., Schalkwijk, C. G., Feskens, E. J., Boer, J. M., Stehouwer, C. D., van der Kallen, C. J. H., & de Bruin, T. W. (2007). Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians. Journal of Clinical Endocrinology & Metabolism, 92(7), 2720-2725. https://doi.org/10.1210/jc.2006-2280
    • op den Buijsch, R. A., van de Plas, A., Stolk, L. M. L., Christiaans, M. H., van Hooff, J. P., Undre, N. A., van Dieijen-Visser, M. P., & Bekers, O. (2007). Evaluation of limited sampling strategies for tacrolimus. European Journal of Clinical Pharmacology, 63(11), 1039-1044. https://doi.org/10.1007/s00228-007-0354-9
    • Veltkamp, M., Wijnen, P. A. H. M., Moorsel, C. H., Rijkers, G. T., Ruven, H. J., Heron, M., Bekers, O., Claessen, A. M., Drent, M., Van den Bosch, J. M. M., & Grutters, J. C. (2007). Linkage between Toll-like receptor (TLR) 2 promotor and intron polymorphisms: functional effects and relevance to sarcoidosis.Clinical and Experimental Immunology, 149(3), 453-462. https://doi.org/10.1111/j.1365-2249.2007.03428.x
    • Wijnen, P. A. H. M., Op den Buisch, R., Drent, M., Kuipers, P. M. J. C., Neefs, C., Bast, A., Bekers, O., & Koek, G. H. (2007). Review article: The prevalence and clinical relevance of cytochrome P450 polymorphisms.Alimentary Pharmacology & Therapeutics, 26(2), 211-219. https://doi.org/10.1111/j.1365-2036.2007.03490.x