• 2016
    • Van Poucke, S., Zhang, Z., Roest, M., Vukicevic, M., Beran, M., Lauwereins, B., Zheng, M.-H., Henskens, Y., Lance, M., & Marcus, A. (2016). Normalization methods in time series of platelet function assays A SQUIRE compliant study. Medicine, 95(28). https://doi.org/10.1097/MD.0000000000004188
    • Linssen, P. B. C., Henry, R. M. A., Schalkwijk, C. G., Dekker, J. M., Nijpels, G., Brunner-La Rocca, H., & Stehouwer, C. D. A. (2016). Serum advanced glycation endproducts are associated with left ventricular dysfunction in normal glucose metabolism but not in type 2 diabetes: The Hoorn Study. Diabetes & Vascular Disease Research, 13(4), 278-285. https://doi.org/10.1177/1479164116640680
    • van Stein, D., Beckers, E. A. M., Peters, A. L., Porcelijn, L., Middelburg, R. A., Lardy, N. M., van Rhenen, D. J., & Vlaar, A. P. J. (2016). Underdiagnosing of antibody-mediated transfusion-related acute lung injury: evaluation of cellular-based versus bead-based techniques. Vox Sanguinis, 111(1), 71-78. https://doi.org/10.1111/vox.12383
    • Claes, G. R. F., van Tienen, F. H. J., Lindsey, P., Krapels, I. P. C., van den Enden, A., Hoos, M., Barrois, Y. E. G., Janssen, J., Paulussen, A. D. C., Sels, J.-W. E. M., Kuijpers, S. H. H., van Tintelen, J. P., van den Berg, M. P., Heesen, W. F., Garcia-Pavia, P., Perrot, A., Christiaans, I., Salemink, S., Marcelis, C. L. M., ... van den Wijngaard, A. (2016). Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers. European Heart Journal, 37(23), 1815-1822. https://doi.org/10.1093/eurheartj/ehv522
    • Simeoni, I., Stephens, J. C., Hu, F., Deevi, S. V. V., Megy, K., Bariana, T. K., Lentaigne, C., Schulman, S., Sivapalaratnam, S., Vries, M. J. A., Westbury, S. K., Greene, D., Papadia, S., Alessi, M.-C., Attwood, A. P., Ballmaier, M., Baynam, G., Bermejo, E., Bertoli, M., ... Turro, E. (2016). A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders. Blood, 127(23), 2791-2803. https://doi.org/10.1182/blood-2015-12-688267
    • Muris, A.-H., Smolders, J., Rolf, L., Klinkenberg, L. J. J., van der Linden, N., Meex, S., Damoiseaux, J., & Hupperts, R. (2016). Vitamin D Status Does Not Affect Disability Progression of Patients with Multiple Sclerosis over Three Year Follow-Up. PLOS ONE, 11(6), Article e0156122. https://doi.org/10.1371/journal.pone.0156122
    • Kleijkers, S. H. M., van Montfoort, A. P. A., Bekers, O., Coonen, E., Derhaag, J. G., Evers, J. L. H., & Dumoulin, J. C. M. (2016). Ammonium accumulation in commercially available embryo culture media and protein supplements during storage at 2-8A degrees C and during incubation at 37A degrees C. Human Reproduction, 31(6), 1192-1199. https://doi.org/10.1093/humrep/dew059
    • Jong, W. M. C., ten Cate, H., Linnenbank, A. C., de Boer, O. J., Reitsma, P. H., de Winter, R. J., & Zuurbier, C. J. (2016). Reduced acute myocardial ischemia-reperfusion injury in IL-6-deficient mice employing a closed-chest model. Inflammation Research, 65(6), 489-499. https://doi.org/10.1007/s00011-016-0931-4
    • Demirkan, A., Lahti, J., Direk, N., Viktorin, A., Lunetta, K. L., Terracciano, A., Nalls, M. A., Tanaka, T., Hek, K., Fornage, M., Wellmann, J., Cornelis, M. C., Ollila, H. M., Yu, L., Smith, J. A., Pilling, L. C., Isaacs, A., Palotie, A., Zhuang, W. V., ... Raeikkoenen, K. (2016). Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Psychological Medicine, 46(8), 1613-1623. https://doi.org/10.1017/S0033291715002081
    • Huskens, D., Roest, M., Remijn, J. A., Konings, J., Kremers, R. M. W., Bloemen, S., Schurgers, E., Selmeczi, A., Kelchtermans, H., van Meel, R., Meex, S. J., Kleinegris, M.-C., de Groot, P. G., Urbanus, R. T., Ninivaggi, M., & de Laat, B. (2016). Strenuous exercise induces a hyperreactive rebalanced haemostatic state that is more pronounced in men. Thrombosis and Haemostasis, 115(6), 1109-1119. https://doi.org/10.1160/TH15-10-0821
    • Driessen, J. H. M., Hansen, L., Eriksen, S. A., van Onzenoort, H. A. W., Henry, R. M. A., van den Bergh, J., Abrahamsen, B., Vestergaard, P., & de Vries, F. (2016). The epidemiology of fractures in Denmark in 2011. Osteoporosis International, 27(6), 2017-2025. https://doi.org/10.1007/s00198-016-3488-8
    • Hoek - ten Cate, A. (2016). Stockings to prevent post-thrombotic syndrome. BMJ, 353, Article i2897. https://doi.org/10.1136/bmj.i2897
    • Heestermans, M., Salloum-Asfar, S., Salvatori, D., Laghmani, E. H., Luken, B. M., Zeerleder, S. S., Spronk, H. M. H., Korporaal, S. J., Wagenaar, G. T. M., Reitsma, P. H., & van Vlijmen, B. J. M. (2016). Retraction: Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice. Blood, 127(21), 2630-2637. https://doi.org/10.1182/blood-2015-10-672766
    • Simsekyilmaz, S., Liehn, E. A., Weinandy, S., Schreiber, F., Megens, R. T. A., Theelen, W., Smeets, R., Jockenhoevel, S., Gries, T., Moeller, M., Klee, D., Weber, C., & Zernecke, A. (2016). Targeting In-Stent-Stenosis with RGD- and CXCL1-Coated Mini-Stents in Mice. PLOS ONE, 11(5), Article e0155829. https://doi.org/10.1371/journal.pone.0155829
    • Verweij, N., Leach, I. M., Isaacs, A., Arking, D. E., Bis, J. C., Pers, T. H., Van den Berg, M. E., Lyytikainen, L.-P., Barnett, P., Wang, X., Soliman, E. Z., Van Duijn, C. M., Kahonen, M., Van Veldhuisen, D. J., Kors, J. A., Raitakari, O. T., Silva, C. T., Lehtimaki, T., Hillege, H. L., ... Van der Harst, P. (2016). Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram. Human Molecular Genetics, 25(10), 2093-2103. https://doi.org/10.1093/hmg/ddw058
    • Wichapong, K., Alard, J. .-E., Ortega-Gomez, A., Weber, C., Hackeng, T. M., Soehnlein, O., & Nicolaes, G. A. F. (2016). Structure-Based Design of Peptidic Inhibitors of the Interaction between CC Chemokine Ligand 5 (CCL5) and Human Neutrophil Peptides 1 (HNP1). Journal of Medicinal Chemistry, 59(9), 4289-4301. https://doi.org/10.1021/acs.jmedchem.5b01952
    • de Rooij, B. H., van der Berg, J. D., van der Kallen, C. J. H., Schram, M. T., Savelberg, H. H. C. M., Schaper, N. C., Dagnelie, P. C., Henry, R. M. A., Kroon, A. A., Stehouwer, C. D. A., & Koster, A. (2016). Physical Activity and Sedentary Behavior in Metabolically Healthy versus Unhealthy Obese and Non-Obese Individuals - The Maastricht Study. PLOS ONE, 11(5), Article e0154358. https://doi.org/10.1371/journal.pone.0154358
    • Koenen, R. R. (2016). Chemokine und adhásionsmolekule bei gefäbentziindungen. Vasomed, 28(3), 116-119.
    • van Sloten, T. T., Mitchell, G. F., Sigurdsson, S., van Buchem, M. A., Jonsson, P. V., Garcia, M. E., Harris, T. B., Henry, R. M. A., Levey, A. S., Stehouwer, C. D. A., Gudnason, V., & Launer, L. J. (2016). Associations between arterial stiffness, depressive symptoms and cerebral small vessel disease: cross-sectional findings from the AGES-Reykjavik Study. Journal of Psychiatry & Neuroscience, 41(3), 162-168. https://doi.org/10.1503/jpn.140334
    • Martens, R., Kooman, J. P., Stehouwer, C. D. A., Dagnelie, P. C., van der Kallen, C. J. H., Koster, A., Kroon, A. A., Leunissen, K. M. L., Nijpels, G., van der Sande, F. M., Schaper, N. C., Sep, S. J. S., Verhey, F. R. J., van Boxtel, M. P. J., Schram, M. T., & Henry, R. M. A. (2016). ESTIMATED GLOMERULAR FILTRATION RATE, (MICRO) ALBUMINURIA AND COGNITIVE PERFORMANCE: THE MAASTRICHT STUDY. Nephrology Dialysis Transplantation, 31(S1), i192. https://doi.org/10.1093/ndt/gfw165.25
    • Agten, S. M., Dawson, P. E., & Hackeng, T. M. (2016). Oxime conjugation in protein chemistry: from carbonyl incorporation to nucleophilic catalysis. Journal of Peptide Science, 22(5), 271-279. https://doi.org/10.1002/psc.2874
    • Weber, C., Doering, Y., & Noels, H. (2016). Potential cell-specific functions of CXCR4 in atherosclerosis. Hämostaseologie, 36(2), 97-102. https://doi.org/10.5482/HAMO-14-10-0054
    • Squizzato, A., Hunt, B. J., Kinasewitz, G. T., Wada, H., ten Cate, H., Thachil, J., Levi, M., Vicente, V., D'Angelo, A., & Di Nisio, M. (2016). Supportive management strategies for disseminated intravascular coagulation: An international consensus. Thrombosis and Haemostasis, 115(5), 896-904. https://doi.org/10.1160/TH15-09-0740
    • Eussen, S. J. P. M., van Dongen, M., Wijckmans, N., den Biggelaar, L., Elferink, S. J. W. H. O., Singh-Povel, C. M., Schram, M. T., Sep, S. J. S., van der Kallen, C. J., Koster, A., Schaper, N., Henry, R. M. A., Stehouwer, C. D. A., & Dagnelie, P. C. (2016). Consumption of dairy foods in relation to impaired glucose metabolism and type 2 diabetes mellitus: the Maastricht Study. British Journal of Nutrition, 115(8), 1453-1461. https://doi.org/10.1017/S0007114516000313
    • Cardinaels, E. P. M., Altintas, S., Versteylen, M. O., Joosen, I. A., Jellema, L.-J. C., Wildberger, J. E., Das, M., Crijns, H. J., Bekers, O., van Dieijen-Visser, M. P., Kietselaer, B. L., & Mingels, A. M. A. (2016). High-Sensitivity Cardiac Troponin Concentrations in Patients with Chest Discomfort: Is It the Heart or the Kidneys As Well?PLOS ONE, 11(4), Article e0153300. https://doi.org/10.1371/journal.pone.0153300
    • Miglianico, M., Nicolaes, G. A. F., & Neumann, D. (2016). Pharmacological Targeting of AMP-Activated Protein Kinase and Opportunities for Computer-Aided Drug Design. Journal of Medicinal Chemistry, 59(7), 2879-2893. https://doi.org/10.1021/acs.jmedchem.5b01201
    • Jainandunsing, S., Wattimena, J. L. D., Verhoeven, A. J. M., Langendonk, J. G., Rietveld, T., Isaacs, A. J., Sijbrands, E. J. G., & de Rooij, F. W. M. (2016). Discriminative Ability of Plasma Branched-Chain Amino Acid Levels for Glucose Intolerance in Families At Risk for Type 2 Diabetes. Metabolic syndrome and related disorders, 14(3), 175-181. https://doi.org/10.1089/met.2015.0102
    • van der Berg, J. D., Stehouwer, C. D., Bosma, H., van der Velde, J. H., Willems, P., Savelberg, H. HCM., Schram, M. T., Sep, S., van der Kallen, C. J., Henry, R. M., Dagnelie, P. C., Schaper, N. C., & Koster, A. (2016). Associations of total amount and patterns of sedentary behaviour with type 2 diabetes and the metabolic syndrome: The Maastricht Study. Diabetologia, 59(4), 709-718. https://doi.org/10.1007/s00125-015-3861-8
    • Mattheij, N. J. A., Swieringa, F., Mastenbroek, T. G., Berny-Lang, M. A., May, F., Baaten, C. C. F. M. J., van der Meijden, P. E. J., Henskens, Y. M. C., Beckers, E. A. M., Suylen, D. P. L., Nolte, M. W., Hackeng, T. M., McCarty, O. J. T., Heemskerk, J. W. M., & Cosemans, J. M. E. M. (2016). Coated platelets function in platelet-dependent fibrin formation via integrin alpha(IIb)beta(3) and transglutaminase factor XIII. Haematologica-the Hematology Journal, 101(4), 427-436. https://doi.org/10.3324/haematol.2015.131441
    • Kimenai, D. M., Henry, R. M. A., van der Kallen, C. J. H., Dagnelie, P. C., Schram, M. T., Stehouwer, C. D. A., van Suijlen, J. D. E., Niens, M., Bekers, O., Sep, S. J. S., Schaper, N. C., van Dieijen-Visser, M. P., & Meex, S. J. R. (2016). Direct comparison of clinical decision limits for cardiac troponin T and I. Heart, 102(8), 610-616. https://doi.org/10.1136/heartjnl-2015-308917
    • Eijgenraam, P., ten Cate, H., Henskens, Y., van den Ham, R., & ten Cate - Hoek , A. (2016). Effects of peri-operative bridging with low molecular weight heparins on coagulation during interruption of vitamin K antagonists: A mechanistic study. Thrombosis Research, 140, 59-65. https://doi.org/10.1016/j.thromres.2016.02.019
    • Fabritz, L., Guasch, E., Antoniades, C., Bardinet, I., Benninger, G., Betts, T. R., Brand, E., Breithardt, G., Bucklar-Suchankova, G., Camm, A. J., Cartlidge, D., Casadei, B., Chua, W. W., Crijns, H., Deeks, J., Hatem, S., Hidden-Lucet, F., Kääb, S., Maniadakis, N., ... Kirchhof, P. (2016). Expert consensus document: Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment. Nature Reviews Cardiology, 13(4), 230-237. https://doi.org/10.1038/nrcardio.2015.194
    • Baaten, C. C. F. M. J., Moenen, F. C. J. I., Henskens, Y. M. C., Swieringa, F., Wetzels, R., van Oerle, R., ten Cate, H., Beckers, E. A. M., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2016). Multiple functional defects in platelets from thrombocytopenic cancer patients undergoing chemotherapy. Thrombosis Research, 140S1, S171-S171. https://doi.org/10.1016/s0049-3848(16)30125-6
    • Swieringa, F., Baaten, C. C. F. M. J., Verdoold, R., Mastenbroek, T. G., Rijnveld, N., van der Laan, K. O., Breel, E. J., Collins, P. W., Lance, M. D., Henskens, Y. M. C., Cosemans, J. M. E. M., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2016). Platelet Control of Fibrin Distribution and Microelasticity in Thrombus Formation Under Flow. Arteriosclerosis Thrombosis and Vascular Biology, 36(4), 692-699. https://doi.org/10.1161/ATVBAHA.115.306537
    • Mahl, C., Egea, V., Megens, R. T. A., Pitsch, T., Santovito, D., Weber, C., & Ries, C. (2016). RECK (reversion-inducing cysteine-rich protein with Kazal motifs) regulates migration, differentiation and Wnt/beta-catenin signaling in human mesenchymal stem cells. Cellular and Molecular Life Sciences, 73(7), 1489-1501. https://doi.org/10.1007/s00018-015-2054-4
    • Ricano-Ponce, I., Zhernakova, D. V., Deelen, P., Luo, O., Li, X., Isaacs, A., Karjalainen, J., Di Tommaso, J., Borek, Z. A., Zorro, M. M., Gutierrez-Achury, J., Uitterlinden, A. G., Hofman, A., van Meurs, J., Netea, M. G., Jonkers, I. H., Withoff, S., van Duijn, C. M., Li, Y., ... Kumar, V. (2016). Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs. Journal of Autoimmunity, 68, 62-74. https://doi.org/10.1016/j.jaut.2016.01.002
    • Cheung, Y. W., Bouman, A. C., Castoldi, E., Wielders, S. J., Spronk, H. M. H., ten Cate, H., Hoek - ten Cate, A., & ten Wolde, M. (2016). Toll-like receptor 9 gene expression in the post-thrombotic syndrome, residual thrombosis and recurrent deep venous thrombosis: A case-control study. Thrombosis Research, 140, 106-109. https://doi.org/10.1016/j.thromres.2016.02.025
    • Rieswijk, L., Claessen, S. M. H., Bekers, O., van Herwijnen, M., Theunissen, D. H. J., Jennen, D. G. J., de Kok, T., Kleinjans, J. C. S., & van Breda, S. G. J. (2016). Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma. Toxicology, 350, 31-39. https://doi.org/10.1016/j.tox.2016.05.002
    • van Overbeek, E. C., Staals, J., Knottnerus, I. L. H., ten Cate, H., & van Oostenbrugge, R. J. (2016). Plasma tPA-Activity and Progression of Cerebral White Matter Hyperintensities in Lacunar Stroke Patients. PLOS ONE, 11(3), Article e0150740. https://doi.org/10.1371/journal.pone.0150740
    • BRIDGE-BPD Consortium, Collaborators, Heemskerk, J., Henskens, Y., & Ouwehand, W. H. (2016). A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies. Science Translational Medicine, 8(328), Article 328ra30. https://doi.org/10.1126/scitranslmed.aad7666
    • Amin, E., Joore, M. A., & Hoek - ten Cate, A. (2016). Compression to prevent PTS: a controversy?Phlebology: The Journal of Venous Disease, 31(1 suppl), 41-47. https://doi.org/10.1177/0268355516632986
    • Bouman, A. C., Ten Cate - Hoek, A., Dirksen, C. D., & Joore, M. A. (2016). Eliciting patients' preferences for elastic compression stocking therapy in patients after deep vein thrombosis: a potential for improving compliance. Journal of Thrombosis and Haemostasis, 14(3), 510–517. https://doi.org/10.1111/jth.13228
    • Gerdes, N., Seijkens, T., Lievens, D., Kuijpers, M. J. E., Winkels, H., Projahn, D., Hartwig, H., Beckers, L., Megens, R. T. A., Boon, L., Noelle, R. J., Soehnlein, O., Heemskerk, J. W. M., Weber, C., & Lutgens, E. (2016). Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes. Arteriosclerosis Thrombosis and Vascular Biology, 36(3), 482-490. https://doi.org/10.1161/ATVBAHA.115.307074
    • Peraramelli, S., Thomassen, S., Heinzmann, A., Hackeng, T. M., Hartmann, R., Scheiflinger, F., Dockal, M., & Rosing, J. (2016). Role of exosite binding modulators in the inhibition of Fxa by TFPI. Thrombosis and Haemostasis, 115(3), 580-590. https://doi.org/10.1160/TH15-04-0354
    • Tten Cate - Hoek, A., Henke, P. K., & Wakefield, T. W. (2016). The post thrombotic syndrome: Ignore it and it will come back to bite you. Blood Reviews, 30(2), 131-137. https://doi.org/10.1016/j.blre.2015.09.002
    • Nagler, M., Bachmann, L. M., ten Cate, H., & ten Cate - Hoek, A. (2016). Diagnostic value of immunoassays for heparin-induced thrombocytopenia: a systematic review and meta-analysis. Blood, 127(5), 546-557. https://doi.org/10.1182/blood-2015-07-661215
    • Hartmann, P., Zhou, Z., Natarelli, L., Wei, Y., Nazari-Jahantigh, M., Zhu, M., Grommes, J., Steffens, S., Weber, C., & Schober, A. (2016). Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4. Nature Communications, 7, Article 10521. https://doi.org/10.1038/ncomms10521
    • Kilpelainen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, A. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikainen, L.-P., ... Loos, R. J. F. (2016). Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nature Communications, 7, Article 10494. https://doi.org/10.1038/ncomms10494
    • Rutten, B., Roest, M., McClellan, E. A., Sels, J. W., Stubbs, A., Jukema, J. W., Doevendans, P. A., Waltenberger, J., van Zonneveld, A.-J., Pasterkamp, G., de Groot, P. G., & Hoefer, I. E. (2016). Platelet density per monocyte predicts adverse events in patients after percutaneous coronary intervention. Thrombosis and Haemostasis, 115(2), 353-360. https://doi.org/10.1160/TH15-03-0227
    • Mattheij, N. J. A., Braun, A., van Kruchten, R., Castoldi, E., Pircher, J., Baaten, C. C. F. M. J., Wuelling, M., Kuijpers, M. J. E., Koehler, R., Poole, A. W., Schreiber, R., Vortkamp, A., Collins, P. W., Nieswandt, B., Kunzelmann, K., Cosemans, J. M. E. M., & Heemskerk, J. W. M. (2016). Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage. Faseb Journal, 30(2), 727-737. https://doi.org/10.1096/fj.15-280446