• 2015
    • Alampour-Rajabi, S., El Bounkari, O., Rot, A., Mueller-Newen, G., Bachelerie, F., Gawaz, M., Weber, C., Schober, A., & Bernhagen, J. (2015). MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP-70 signaling, and lymphocyte chemotaxis. Faseb Journal, 29(11), 4497-4511. https://doi.org/10.1096/fj.15-273904
    • Back, M., Weber, C., & Lutgens, E. (2015). Regulation of atherosclerotic plaque inflammation. Journal of Internal Medicine, 278(5), 462-482. https://doi.org/10.1111/joim.12367
    • Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., Kelly, T. N., Saleheen, D., Lehne, B., Leach, I. M., Drong, A. W., Abbott, J., Wahl, S., Tan, S.-T., Scott, W. R., Campanella, G., Chadeau-Hyam, M., Afzal, U., Ahluwalia, T. S., ... Author collaboration (2015). Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nature Genetics, 47(11), 1282–1293. https://doi.org/10.1038/ng.3405
    • Driessen, J. H. M., van Onzenoort, H. A. W., Starup-Linde, J., Henry, R., Burden, A. M., Neef, C., van den Bergh, J. P., Vestergaard, P., & de Vries, F. (2015). Use of Glucagon-Like-Peptide 1 Receptor Agonists and Risk of Fracture as Compared to Use of Other Anti-hyperglycemic Drugs. Calcified Tissue International, 97(5), 506-515. https://doi.org/10.1007/s00223-015-0037-y
    • Cardinaels, E. P., Cornelis, T., van der Sande, F. M., Leunissen, K. M., van Dieijen-Visser, M. P., Mingels, A. M., Kooman, J. P., & Bekers, O. (2015). Acute effects of conventional and extended hemodialysis and hemodiafiltration on high-sensitivity cardiac troponins. Clinical Chemistry and Laboratory Medicine, 53(11), e289-e292. https://doi.org/10.1515/cclm-2015-0201
    • Selle, J., Asare, Y., Kohncke, J., Alampour-Rajabi, S., Shagdarsuren, G., Klos, A., Weber, C., Jankowski, J., & Shagdarsuren, E. (2015). Atheroprotective role of C5ar2 deficiency in apolipoprotein E-deficient mice. Thrombosis and Haemostasis, 114(4), 848-858. https://doi.org/10.1160/TH14-12-1075
    • Tjon-Kon-Fat, R. I., Bensdorp, A. J., Bossuyt, P. M. M., Koks, C., Oosterhuis, G. J. E., Hoek - ten Cate, A., Hompes, P., Broekmans, F. J., Verhoeve, H. R., de Bruin, J. P., van Golde, R., Repping, S., Cohlen, B. J., Lambers, M. D. A., van Bommel, P. F., Slappendel, E., Perquin, D., Smeenk, J., Pelinck, M. J., ... van Wely, M. (2015). Is IVF-served two different ways-more cost-effective than IUI with controlled ovarian hyperstimulation?Human Reproduction, 30(10), 2331-2339. https://doi.org/10.1093/humrep/dev193
    • Grottke, O., Honickel, M., van Ryn, J., ten Cate, H., Rossaint, R., & Spronk, H. M. (2015). Idarucizumab, a Specific Dabigatran Reversal Agent, Reduces Blood Loss in a Porcine Model of Trauma With Dabigatran Anticoagulation. Journal of the American College of Cardiology, 66(13), 1518-1519. https://doi.org/10.1016/j.jacc.2015.07.051
    • UK10K Consortium, & Isaacs, A. (2015). Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel. Nature Communications, 6, 8111. Article 8111. https://doi.org/10.1038/ncomms9111
    • van der Vorst, E. P. C., Doring, Y., & Weber, C. (2015). Chemokines and their receptors in Atherosclerosis. Journal of Molecular Medicine, 93(9), 963-971. https://doi.org/10.1007/s00109-015-1317-8
    • Vissenberg, R., van Dijk, M. M., Fliers, E., van der Post, J. A. M., van Wely, M., Bloemenkamp, K. W. M., Hoek - ten Cate, A., Kuchenbecker, W. K., Verhoeve, H. R., Scheepers, H. C. J., Rombout-de Weerd, S., Koks, C., Zwart, J. J., Broekmans, F., Verpoest, W., Christiansen, O. B., Post, M., Papatsonis, D. N. M., Verberg, M. F. G., ... Goddijn, M. (2015). Effect of levothyroxine on live birth rate in euthyroid women with recurrent miscarriage and TPO antibodies (T4-LIFE study). Contemporary Clinical Trials, 44, 134-138. https://doi.org/10.1016/j.cct.2015.08.005
    • Wildhagen, K. C. A. A., Wiewel, M. A., Schultz, M. J., Horn, J., Schrijver, R., Reutelingsperger, C. P. M., van der Poll, T., & Nicolaes, G. A. F. (2015). Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patients. Thrombosis Research, 136(3), 542-547. https://doi.org/10.1016/j.thromres.2015.06.035
    • Baaten, C. C. F. M. J., Veenstra, L. F., Wetzels, R., van Geffen, J. P., Swieringa, F., de Witt, S. M., Henskens, Y. M. C., Crijns, H., Nylander, S., van Giezen, J. J. J., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2015). Gradual increase in thrombogenicity of juvenile platelets formed upon offset of prasugrel medication. Haematologica-the Hematology Journal, 100(9), 1131-1138. https://doi.org/10.3324/haematol.2014.122457
    • Hoek - ten Cate, A. J., ten Cate, H., Henskens, Y., van der Meijden, P. E. J., Spronk, H. M. H., & Wittens, C. (2015). Maastricht Consensus Conference on Thrombosis (MCCT): A roadmap for future research, February 11-13, 2015, Maastricht, The Netherlands. Thrombosis Research, 136, S1-S2. https://doi.org/10.1016/j.thromres.2015.07.033
    • van der Meijden, P. E. J., Ozaki, Y., Ruf, W., de Laat, B., Mutch, N., Diamond, S., Nieuwland, R., Peters, T. C., Heestermans, M., Kremers, R. M. W., Moorlag, M., Boender, J., Unlu, B., & Reitsma, P. H. (2015). Theme 1: Pathogenesis of venous thromboembolism (and post-thrombotic syndrome). Thrombosis Research, 136, S3-S7. https://doi.org/10.1016/j.thromres.2015.07.034
    • Spronk, H. M. H., Cannegieter, S., Morange, P., Hackeng, T., Huisman, M., Nagler, M., Posthuma, J., Ninivaggi, M., Zwaveling, S., van der Hulle, T., Scheres, L. J. J., van Mens, T. E., & Mackman, N. (2015). Theme 2: Epidemiology, Biomarkers, and Imaging of Venous Thromboembolism (and postthrombotic syndrome). Thrombosis Research, 136, S8-S12. https://doi.org/10.1016/j.thromres.2015.07.035
    • ten Cate-Hoek, A. J., Weitz, J. I., Gailani, D., Meijer, K., Philippou, H., Bouman, A. C., Whitney Cheung, Y., van Mens, T. E., Govers-Riemslag, J. W., Vries, M., Bleker, S., Biedermann, J. S., Stoof, S. C. M., & Buller, H. R. (2015). Theme 3: Non-invasive management of (recurrent) venous thromboembolism (VTE) and post thrombotic syndrome (PTS). Thrombosis Research, 136(Supplement 1), S13-S18. https://doi.org/10.1016/j.thromres.2015.07.036
    • Pawig, L., Klasen, C., Weber, C., Bernhagen, J., & Noels, H. (2015). Diversity and inter-connections in the CXCR4 chemokine receptor/ligand family: molecular perspectives. Frontiers in Immunology, 6(AUG), Article 429. https://doi.org/10.3389/fimmu.2015.00429
    • Medina, I., Cougoule, C., Drechsler, M., Bermudez, B., Koenen, R. R., Sluimer, J., Wolfs, I., Doering, Y., Herias, V., Gijbels, M., Bot, I., de Jager, S. C. A., Weber, C., Cleutjens, J., van Berkel, T. J. C., Sikkink, K.-J., Mocsai, A., Maridonneau-Parini, I., Soehnlein, O., & Biessen, E. A. L. (2015). Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility. Circulation, 132(6), 490-501. https://doi.org/10.1161/CIRCULATIONAHA.114.012316
    • Wijnands, J. M. A., Boonen, A., van Sloten, T. T., Schram, M. T., Sep, S. J. S., Koster, A., van der Kallen, C. J. H., Henry, R. M. A., Dagnelie, P. C., Stehouwer, C. D. A., van der Linden, S., & Arts, I. C. W. (2015). Association between serum uric acid, aortic, carotid and femoral stiffness among adults aged 40-75 years without and with type 2 diabetes mellitus: The Maastricht Study. Journal of Hypertension, 33(8), 1642-1650. https://doi.org/10.1097/HJH.0000000000000593
    • Loeffen, R., Winckers, K., Ford, I., Jukema, J. W., Robertson, M., Stott, D. J., Spronk, H. M., ten Cate, H., & Lowe, G. D. (2015). Associations Between Thrombin Generation and the Risk of Cardiovascular Disease in Elderly Patients: Results From the PROSPER Study. Journals of Gerontology - Series A, 70(8), 982-988. https://doi.org/10.1093/gerona/glu228
    • Driessen, J. H. M., Henry, R. M. A., van Onzenoort, H. A. W., Lalmohamed, A., Burden, A. M., Prieto-Alhambra, D., Neef, C., Leufkens, H. G. M., & de Vries, F. (2015). Bone Fracture Risk is Not Associated with the Use of Glucagon-Like Peptide-1 Receptor Agonists: A Population-Based Cohort Analysis. Calcified Tissue International, 97(2), 104-112. https://doi.org/10.1007/s00223-015-9993-5
    • Spauwen, P. J. J., van Boxtel, M. P. J., Verhey, F. R. J., Kohler, S., Sep, S. J. S., Koster, A., Dagnelie, P. C., Henry, R. M. A., Schaper, N. C., van der Kallen, C. J. H., Schram, M. T., Kroon, A. A., & Stehouwer, C. D. A. (2015). Both Low and High 24-Hour Diastolic Blood Pressure Are Associated With Worse Cognitive Performance in Type 2 Diabetes: The Maastricht Study. Diabetes Care, 38(8), 1473-1480. https://doi.org/10.2337/dc14-2502
    • Swieringa, F., Lance, M. D., Fuchs, B., Feijge, M. A. H., Solecka, B. A., Verheijen, L. P. J., Hughes, K. R., Van Oerle, R., Deckmyn, H., Kannicht, C., Heemskerk, J. W. M., & Van der Meijden, P. E. J. (2015). Desmopressin treatment improves platelet function under flow in patients with postoperative bleeding. Journal of Thrombosis and Haemostasis, 13(8), 1503-1513. https://doi.org/10.1111/jth.13007
    • Vajen, T., Mause, S. F., & Koenen, R. R. (2015). Microvesicles from platelets: novel drivers of vascular inflammation. Thrombosis and Haemostasis, 114(2), 228-236. https://doi.org/10.1160/TH14-11-0962
    • Konings, J., Hoving, L. R., Ariens, R. S., Hethershaw, E. L., Ninivaggi, M., Hardy, L. J., de Laat, B., ten Cate, H., Philippou, H., & Govers-Riemslag, J. W. P. (2015). The role of activated coagulation factor XII in overall clot stability and fibrinolysis. Thrombosis Research, 136(2), 474-480. https://doi.org/10.1016/j.thromres.2015.06.028
    • van der Vorst, E. P. C., Doering, Y., & Weber, C. (2015). MIF and CXCL12 in cardiovascular diseases: functional differences and similarities. Frontiers in Immunology, 6(JUL), Article 373. https://doi.org/10.3389/fimmu.2015.00373
    • Loeffen, R., Godschalk, T. C., van Oerle, R., Spronk, H. M. H., Hackeng, C. M., ten Berg, J. M., & ten Cate, H. (2015). The hypercoagulable profile of patients with stent thrombosis. Heart, 101(14), 1126-1132. https://doi.org/10.1136/heartjnl-2014-306685
    • BIOS Consortium, & Isaacs, A. (2015). Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations. American Journal of Human Genetics, 97(1), 75-85. https://doi.org/10.1016/j.ajhg.2015.05.014
    • van Sloten, T. T., Czernichow, S., Houben, A. J., Protogerou, A. D., Henry, R. M., Muris, D. M., Schram, M. T., Sep, S. J., Dagnelie, P. C., van der Kallen, C. J., Schaper, N. C., Blacher, J., Hercberg, S., Levy, B. I., & Stehouwer, C. D. (2015). Association Between Arterial Stiffness and Skin Microvascular Function: The SUVIMAX2 Study and The Maastricht Study. American Journal of Hypertension, 28(7), 868-876. https://doi.org/10.1093/ajh/hpu246
    • ENGAGE Consortium (2015). Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. Plos Genetics, 11(7), Article e1005230. https://doi.org/10.1371/journal.pgen.1005230
    • den Exter, P. L., van Es, J., Kroft, L. J. M., Erkens, P. M. G., Douma, R. A., Mos, I. C. M., Jonkers, G., Hovens, M. M. C., Durian, M. F., ten Cate, H., Beenen, L. F. M., Kamphuisen, P. W., & Huisman, M. V. (2015). Thromboembolic resolution assessed by CT pulmonary angiography after treatment for acute pulmonary embolism. Thrombosis and Haemostasis, 114(1), 26-34. https://doi.org/10.1160/TH14-10-0842
    • Spronk, H. M. H., Braunschweig, T., Rossaint, R., Wuest, D. C., van Oerle, R., Lauritzen, B., Tolba, R., & Grottke, O. (2015). Recombinant Factor VIIa Reduces Bleeding after Blunt Liver Injury in a Pig Model of Dilutional Coagulopathy under Severe Hypothermia. PLOS ONE, 10(6), Article e0113979. https://doi.org/10.1371/journal.pone.0113979
    • Hu, D., Mohanta, S. K., Yin, C., Peng, L., Ma, Z., Srikakulapu, P., Grassia, G., MacRitchie, N., Dever, G., Gordon, P., Burton, F. L., Ialenti, A., Sabir, S. R., McInnes, I. B., Brewer, J. M., Garside, P., Weber, C., Lehmann, T., Teupser, D., ... Habenicht, A. J. R. (2015). Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin beta Receptors. Immunity, 42(6), 1100-1115. https://doi.org/10.1016/j.immuni.2015.05.015
    • Draisma, H. H. M., Pool, R., Kobl, M., Jansen, R., Petersen, A.-K., Vaarhorst, A. A. M., Yet, I., Haller, T., Demirkan, A., Esko, T., Zhu, G., Böhringer, S., Beekman, M., van Klinken, J. B., Römisch-Margl, W., Prehn, C., Adamski, J., de Craen, A. J. M., van Leeuwen, E. M., ... Boomsma, D. I. (2015). Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nature Communications, 6, 7208. https://doi.org/10.1038/ncomms8208
    • Jamasbi, J., Megens, R. T. A., Bianchini, M., Muench, G., Ungerer, M., Faussner, A., Sherman, S., Walker, A., Goyal, P., Jung, S., Brandl, R., Weber, C., Lorenz, R., Farndale, R., Elia, N., & Siess, W. (2015). Differential Inhibition of Human Atherosclerotic Plaque-Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies Functional and Imaging Studies. Journal of the American College of Cardiology, 65(22), 2404-2415. https://doi.org/10.1016/j.jacc.2015.03.573
    • van Sloten, T. T., Protogerou, A. D., Henry, R. M. A., Schram, M. T., Launer, L. J., & Stehouwer, C. D. A. (2015). Association between arterial stiffness, cerebral small vessel disease and cognitive impairment: A systematic review and meta-analysis. Neuroscience and Biobehavioral Reviews, 53, 121-130. https://doi.org/10.1016/j.neubiorev.2015.03.011
    • WiN Study Group (2015). CLEC4M and STXBP5 gene variations contribute to von Willebrand factor level variation in von Willebrand disease. Journal of Thrombosis and Haemostasis, 13(6), 956-66. https://doi.org/10.1111/jth.12927
    • Haer-Wigman, L., Stegmann, T. C., Solati, S., Ait Soussan, A., Beckers, E., van der Harst, P., van Hulst-Sundermeijer, M., Ligthart, P., van Rhenen, D., Schepers, H., de Haas, M., & van der Schoot, C. E. (2015). Impact of genetic variation in the SMIM1 gene on Vel expression levels. Transfusion, 55(6), 1457-1466. https://doi.org/10.1111/trf.13014
    • Curaj, A., Wu, Z., Fokong, S., Liehn, E. A., Weber, C., Burlacu, A., Lammers, T., van Zandvoort, M., & Kiessling, F. (2015). Noninvasive Molecular Ultrasound Monitoring of Vessel Healing After Intravascular Surgical Procedures in a Preclinical Setup. Arteriosclerosis Thrombosis and Vascular Biology, 35(6), 1366-1373. https://doi.org/10.1161/ATVBAHA.114.304857
    • Megens, R. T. A., Bianchini, M., Schmitt, M. M. N., & Weber, C. (2015). Optical Imaging Innovations for Atherosclerosis Research Multiphoton Microscopy and Optical Nanoscopy. Arteriosclerosis Thrombosis and Vascular Biology, 35(6), 1339-1346. https://doi.org/10.1161/ATVBAHA.115.304875
    • Kuijpers, M. J. E., Mattheij, N. J. A., Cipolla, L., van Geffen, J. P., Lawrence, T., Donners, M. M. P. C., Boon, L., Lievens, D., Torti, M., Noels, H., Gerdes, N., Cosemans, J. M. E. M., Lutgens, E., & Heemskerk, J. W. M. (2015). Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase beta, and Not Via CD40 and I kappa B Kinase alpha. Arteriosclerosis Thrombosis and Vascular Biology, 35(6), 1374-1381. https://doi.org/10.1161/ATVBAHA.114.305127
    • Swieringa, F., Kuijpers, M. J. E., Lamers, M. M. E., van der Meijden, P. E. J., & Heemskerk, J. W. M. (2015). Rate-limiting roles of the tenase complex of factors VIII and IX in platelet procoagulant activity and formation of platelet-fibrin thrombi under flow. Haematologica-the Hematology Journal, 100(6), 748-756. https://doi.org/10.3324/haematol.2014.116863
    • Grottke, O., & ten Cate, H. (2015). Reply to Faraoni D, Fenger-Eriksen C, Gillard S et al. Evaluation of dynamic parameters of thrombus formation measured on whole blood using rotational thromboelastometry in children undergoing cardiac surgery: a descriptive study. Pediatric Anesthesia, 25(6), 646-647. https://doi.org/10.1111/pan.12650
    • Surakka, I., Horikoshi, M., Mägi, R., Sarin, A.-P., Mahajan, A., Lagou, V., Marullo, L., Ferreira, T., Miraglio, B., Timonen, S., Kettunen, J., Pirinen, M., Karjalainen, J., Thorleifsson, G., Hägg, S., Hottenga, J.-J., Isaacs, A., Ladenvall, C., Beekman, M., ... Ripatti, S. (2015). The impact of low-frequency and rare variants on lipid levels. Nature Genetics, 47(6), 589-97. https://doi.org/10.1038/ng.3300
    • Hu, Q., van Gaal, E. V. B., Brundel, P., Ippel, H., Hackeng, T., Rijcken, C. J. F., Storm, G., Hennink, W. E., & Prakash, J. (2015). A novel approach for the intravenous delivery of leuprolide using core-cross-linked polymeric micelles. Journal of Controlled Release, 205, 98-108. https://doi.org/10.1016/j.jconrel.2014.12.023
    • Hermanns, M. I., Grossmann, V., Spronk, H. M. H., Schulz, A., Juenger, C., Laubert-Reh, D., Mazur, J., Gori, T., Zeller, T., Pfeiffer, N., Beutel, M., Blankenberg, S., Muenzel, T., Lackner, K. J., Hoek - ten Cate, A. J., ten Cate, H., & Wild, P. S. (2015). Distribution, genetic and cardiovascular determinants of FVIII:c - Data from the population-based Gutenberg Health Study. International Journal of Cardiology, 187(1), 166-174. https://doi.org/10.1016/j.ijcard.2015.03.330
    • van den Berg, S. M., Seijkens, T. T. P., Kusters, P. J. H., Zarzycka, B., Beckers, L., den Toom, M., Gijbels, M. J. J., Chatzigeorgiou, A., Weber, C., de Winther, M. P. J., Chavakis, T., Nicolaes, G. A. F., & Lutgens, E. (2015). Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice. International Journal of Obesity, 39(5), 782-790. https://doi.org/10.1038/ijo.2014.198
    • Geenen, I. L. A., Molin, D. G. M., van den Akker, N. M. S., Jeukens, F., Spronk, H. M., Schurink, G. W. H., & Post, M. J. (2015). Endothelial cells (ECs) for vascular tissue engineering: venous ECs are less thrombogenic than arterial ECs. Journal of Tissue Engineering and Regenerative Medicine, 9(5), 564-576. https://doi.org/10.1002/term.1642