Publications
- 2025
- Xin, X., & Koenen, R. R. (2025). Assessing platelet-derived extracellular vesicles for potential as therapeutic targets in cardiovascular diseases. Expert Opinion on Therapeutic Targets, 29(1-2), 17-28. https://doi.org/10.1080/14728222.2025.2454617
- Ceulemans, A., Barakzie, A., Spronk, H. M. H., de Maat, M. P. M., van Beusekom, H. M. M., Taha, A., Emmer, B. J., Roos, Y. B. W. E. M., Dippel, D. W. J., Majoie, C. B. L. M., van Zwam, W. H., ten Cate, H., van Oostenbrugge, R. J., & Nagy, M. (2025). Association between coagulation activity and clinical and imaging outcomes in acute ischemic stroke patients - A sub-study of the MR CLEAN NO-IV trial. Thrombosis Research, 245, Article 109212. https://doi.org/10.1016/j.thromres.2024.109212
- Albu, E., Gao, S., Stijnen, P., Rademakers, F. E., van Bussel, B. C. T., Collyer, T., Hernandez-Boussard, T., Wynants, L., & Van Calster, B. (2025). Challenges and Recommendations for Electronic Health Records Data Extraction and Preparation for Dynamic Prediction Modeling in Hospitalized Patients: Practical Guide and Tutorial. Journal of Medical Internet Research, 27(1), Article e73987. https://doi.org/10.2196/73987
- van Mourik, D. J. M., Jansen, V. L. B. I., Coppens, M., Middeldorp, S., ten Cate, H., Buller, H. R., Spronk, H. M. H., Nagy, M., & van Mens, T. E. (2025). Intrinsic pathway activation in patients with antiphospholipid syndrome and healthy controls. Research and practice in thrombosis and haemostasis, 9(1), Article 102694. https://doi.org/10.1016/j.rpth.2025.102694
- Mozaffari, S., Moen, A., Ng, C. Y., Nicolaes, G. A. F., & Wichapong, K. (2025). Structural bioinformatics for rational drug design. Research and practice in thrombosis and haemostasis, 9(1), Article e102691. https://doi.org/10.1016/j.rpth.2025.102691
- Hupperetz, R., & Ten Cate-Hoek, A. (2025). The Postthrombotic syndrome, where are we now?Vasa-European Journal of Vascular Medicine, 54(1), 7-19. https://doi.org/10.1024/0301-1526/a001156
- Barakzie, A., Jansen, G. A. J., Cavalcante, F., Nagy, M., Dippel, D. W. J., van der Lugt, A., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Cate, H. T., de Maat, M. P. M., & CONTRAST Consortium (2025). Association of primary and secondary hemostasis biomarkers with acute ischemic stroke outcome in patients undergoing thrombectomy, with or without thrombolytics: post hoc analysis of the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands-NO IV. Journal of Thrombosis and Haemostasis, 23(1), 235-247. https://doi.org/10.1016/j.jtha.2024.10.008
- Monegatti, S., Martinelli, N., Friso, S., Spronk, H. M., & Ten Cate, H. (2025). Mechanisms and management of thrombosis in cancer: focus on gastrointestinal malignancies. Journal of Pharmacology and Experimental Therapeutics, 392(1), Article 100018. https://doi.org/10.1124/jpet.124.002203
- Meex, S. J. R., & Aakre, K. M. (2025). Personalized ranges for blood-test results enable precision diagnostics. Nature, 637(8045), 279-280. https://doi.org/10.1038/d41586-024-03854-9
- Sileo, A., Gabetti, S., Gulan, A. C., Cervenka, I., Zhang, C., Mingels, A., Milan, G., Massai, D., & Marsano, A. (2025). Asymmetric biphasic electric stimulation supports cardiac maturation and functionality. Journal of Tissue Engineering, 16, Article 20417314251393556. https://doi.org/10.1177/20417314251393556
- Kuc, S., Wijnen, P., Erckens, R., Gijs, M., Webers, C. A. B., Bekers, O., & Drent, M. (2025). Clinical Patterns of Sarcoidosis Patients with and without Uveitis: Insights from a Dutch Sarcoidosis Centre. Ocular Immunology and Inflammation, 33(1), 125-132. https://doi.org/10.1080/09273948.2024.2369931
- Wiedemann, N., Korte-De Boer, D. D., Richter, M., Weijer, S. V. D., Buhre, C., Eggert, F. A. M., Aarnoudse, S., Grevendonk, L., Röber, S., Remie, C. M. E., Buhre, W., Henry, R., & Born, J. (2025). COVID-BLUeS - A Prospective Study on the Value of AI in Lung Ultrasound Analysis. IEEE Journal of Biomedical and Health Informatics, 29(9), 6301-6310. https://doi.org/10.1109/JBHI.2025.3543686
- Rocca, B., & Cate, H. T. (2025). Factor XI and Atrial Fibrillation: A Mismatched Pairing?European Cardiology Review, 20, Article e08. https://doi.org/10.15420/ecr.2024.61
- Spoormans, E. M., Thevathasan, T., Van Royen, N., Zwinderman, A. H., Freund, A., Thiele, H., Ziesemer, K., Desch, S., Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., ... COACT and TOMAHAWK Trials Investigators (2025). One-Year Outcomes of Coronary Angiography After Out-of-Hospital Cardiac Arrest Without ST Elevation: An Individual Patient Data Meta-Analysis. JAMA Cardiology, 10(8), 779-786. https://doi.org/10.1001/jamacardio.2025.1194
- Bari, G., Mariani, S., van Bussel, B. C. T., Di Mauro, M., Conci, L., Saeed, D., Pozzi, M., Loforte, A., Boeken, U., Samalavicius, R., Bounader, K., Hou, X., J H Bunge, J., Buscher, H., Salazar, L., Meyns, B., Mazzeffi, M., Matteucci, S., Sponga, S., ... PELS Investigators (2025). Post-Cardiotomy Extracorporeal Life Support Following Aortic Surgery. Asaio Journal. Advance online publication. https://doi.org/10.1097/MAT.0000000000002619
- Hesselink, G., Verhage, R., Westerhof, B., Verweij, E., Fuchs, M., Janssen, I., van der Meer, C., van der Horst, I. C. C., de Jong, P., van der Hoeven, J. G., & Zegers, M. (2025). Reducing administrative burden by implementing a core set of quality indicators in the ICU: a multicentre longitudinal intervention study. BMJ Quality and Safety, 34(3), 157-165. https://doi.org/10.1136/bmjqs-2024-017481
- 2024
- Wortel, S. A., Bakhshi-Raiez, F., Abu-Hanna, A., Dongelmans, D. A., Keizer, N. F. D., Houwink, A., Dijkhuizen, A., Draisma, A., Rijkeboer, A., Cloïn, A., Meijer, A. D., Reidinga, A., Festen-Spanjer, B., van Bussel, B., Eikemans, B., Jacobs, C., Moolenaar, D., Ramnarain, D., Koning, D., ... Dutch COVID-19 Research Consortium (2024). Long-term mortality of Dutch COVID-19 patients admitted to the intensive care medicine: a retrospective analysis from a national quality registry. Critical Care Science, 36, Article e202400251en. https://doi.org/10.62675/2965-2774.20240251-en
- Velt, M. J. H., Crijns, H. J. G. M., van Gelder, I. C., Linz, D., van de Lande, M. E., Ten Cate, H., Spronk, H. M. H., de Melis, M., Rienstra, M., & Mulder, B. A. (2024). Dynamic biomarker profiles in patients with paroxysmal atrial fibrillation: Assessing the differences between sinus rhythm and acute atrial fibrillation episode. International Journal of Cardiology, 417, Article 132526. https://doi.org/10.1016/j.ijcard.2024.132526
- de Laat-Kremers, R., Huang, S., ten Cate, H., Ninivaggi, M., de Laat, B., & Devreese, K. (2024). Interpreting high levels of unfolded Von Willebrand Factor in patients with the antiphospholipid syndrome. Frontiers in Immunology, 15, Article 1514433. https://doi.org/10.3389/fimmu.2024.1514433
- Reyat, J. S., Sommerfeld, L. C., O'Reilly, M., Cardoso, V. R., Thiemann, E., Khan, A. O., O'Shea, C., Harder, S., Müller, C., Barlow, J., Stapley, R. J., Chua, W., Kabir, S. N., Grech, O., Hummel, O., Hübner, N., Kääb, S., Mont, L., Hatem, S. N., ... Fabritz, L. (2024). PITX2 deficiency leads to atrial mitochondrial dysfunction. Cardiovascular Research, 120(15), 1907-1923. https://doi.org/10.1093/cvr/cvae169
- Hansildaar, R., Raadsen, R., Gerritsen, M., Nagy, M., Dijkshoorn, B., Spronk, H. M. H., Ten Cate, H., & Nurmohamed, M. T. (2024). Comparative Analysis of Coagulation Activation in Rheumatoid Arthritis Patients Treated With TNF Inhibitors Versus JAK Inhibitors: A Longitudinal Study. Journal of Clinical Rheumatology, 30(8), e166-e171. Article 002136. https://doi.org/10.1097/RHU.0000000000002136
- Baaten, C. C. F. M. J., Nagy, M., Spronk, H. M. H., Ten Cate, H., & Kietselaer, B. L. J. H. (2024). NETosis in Cardiovascular Disease: An Opportunity for Personalized Antithrombotic Treatments?Arteriosclerosis Thrombosis and Vascular Biology, 44(12), 2366-2370. https://doi.org/10.1161/ATVBAHA.124.320150
- Lemmens, T. P., Luo, Q., Wielders, S. J. H., Scheijen, J. L. J. M., Al-Nasiry, S., Koenen, R. R., Wenzel, P., & Cosemans, J. M. E. M. (2024). Platelet collagen receptors and their role in modulating platelet adhesion patterns and activation on alternatively processed collagen substrates. Thrombosis Research, 244, Article 109201. https://doi.org/10.1016/j.thromres.2024.109201
- Jooss, N. J., Diender, M. G., Fernandez, D. I., Huang, J., Heubel-Moenen, F. C. J., van der Veer, A., Kuijpers, M. J. E., Poulter, N. S., Henskens, Y. M. C., te Loo, M., & Heemskerk, J. W. M. (2024). Restraining of glycoprotein VI- and integrin α2β1-dependent thrombus formation by platelet PECAM1. Cellular and Molecular Life Sciences, 81(1), Article 44. https://doi.org/10.1007/s00018-023-05058-2
- Chai, J., Wu, J., Yang, J., Ye, T., Gao, Y., Zeng, B., Xiong, W., Kotsyfakis, M., Dijkgraaf, I., Liu, J., Chen, X., & Xu, X. (2024). Cath-HG improves the survival rates and symptoms in LPS-induced septic mice due to its multifunctional properties. International Immunopharmacology, 143(Pt 1), Article 113332. https://doi.org/10.1016/j.intimp.2024.113332
- Mariani, S., Ravaux, J. M., van Bussel, B. C. T., De Piero, M. E., van Kruijk, S. M. J., Schaefer, A.-K., Wiedemann, D., Saeed, D., Pozzi, M., Loforte, A., Boeken, U., Samalavicius, R., Bounader, K., Hou, X., Bunge, J. J. H., Buscher, H., Salazar, L., Meyns, B., Mazzeffi, M. A., ... Post-Cardiotomy Extracorporeal Life Support (PELS-1) Investigators (2024). Features and outcomes of female and male patients requiring postcardiotomy extracorporeal life support. Journal of Thoracic and Cardiovascular Surgery, 168(6), 1701-1711.e30. https://doi.org/10.1016/j.jtcvs.2024.04.033
- de Jong, M. J., Saadan, H., van der Hooft, B. H. M., Hellenbrand, D. L. S., Brüggemann, R. A. G., Ten Cate, H., van Kuijk, S. M. J., van Geel, R. M. J. M., Henskens, Y. M. C., Winckers, K., & Magdelijns, F. J. H. (2024). Intra-Individual Variability of Direct Oral Anticoagulant Levels in Frail Older Patients upon, during, and after Acute Hospitalization: the DOAC-FRAIL Study. Journal of the American Medical Directors Association, 25(12), Article 105280. https://doi.org/10.1016/j.jamda.2024.105280
- Hupperetz, R. D., Iding, A. F., van Laanen, J., Brans, R., Notten, P., Tick, L. W., Vleming, L.-J., Jie, A., Planken, N., Wittens, C. H. A., Ten Cate, H., & Ten Cate-Hoek, A. J. (2024). Patency and reflux in relation to post-thrombotic syndrome: a subanalysis of the Ultrasound-Accelerated Catheter-Directed Thrombolysis Versus Anticoagulation for the Prevention of Post-Thrombotic Syndrome trial. Journal of Thrombosis and Haemostasis, 22(12), 3552-3561. https://doi.org/10.1016/j.jtha.2024.08.022
- Zou, J., Zhang, P., Solari, F. A., Schönichen, C., Provenzale, I., Mattheij, N. J. A., Kuijpers, M. J. E., Rauch, J. S., Swieringa, F., Sickmann, A., Zieger, B., Jurk, K., & Heemskerk, J. W. M. (2024). Suppressed ORAI1-STIM1-dependent Ca2+ entry by protein kinase C isoforms regulating platelet procoagulant activity. Journal of Biological Chemistry, 300(12), Article 107899. https://doi.org/10.1016/j.jbc.2024.107899
- Fernández, D. I., Troitiño, S., Sobota, V., Tullemans, B. M. E., Zou, J., van den Hurk, H., García, Á., Honarnejad, S., Kuijpers, M. J. E., & Heemskerk, J. W. M. (2024). Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics. Scientific Reports, 14(1), Article 6229. https://doi.org/10.1038/s41598-024-56799-4
- Boschetti, L., Nilius, H., Ten Cate, H., Wuillemin, W. A., Faes, L., Bossuyt, P. M., Bachmann, L. M., & Nagler, M. (2024). Design-related bias in studies investigating diagnostic tests for venous thromboembolic diseases: a systematic review and meta-analysis. Frontiers in Cardiovascular Medicine, 11, Article 1420000. https://doi.org/10.3389/fcvm.2024.1420000
- Heyens, L., Kenjic, H., Dagnelie, P., Schalkwijk, C., Stehouwer, C., Meex, S., Kooman, J., Bekers, O., van Greevenbroek, M., Savelberg, H., Robaeys, G., de Galan, B., Koster, A., van Dongen, M., Eussen, S., & Koek, G. (2024). Forns index and fatty liver index, but not FIB-4, are associated with indices of glycaemia, pre-diabetes and type 2 diabetes: analysis of The Maastricht Study. BMJ Open Gastroenterology, 11(1), Article e001466. https://doi.org/10.1136/bmjgast-2024-001466
- Ranalli, P., & Ten Cate, H. (2024). Venous Thromboembolism Prophylaxis after hematopoietic cell transplantation: Still a Challenge for Hematologists and Hemostasiologists. Thrombosis and Haemostasis, 125(2), 163-165. https://doi.org/10.1055/a-2434-5010
- Monard, A. L. L., Mussert, C. M. A., van Duijl, T. T., Kruip, M. J. H. A., Henskens, Y. M. C., van den Biggelaar, M., Schutgens, R. E. G., Schols, S. E. M., Fijnvandraat, K. J., Meijer, K., den Exter, P. L., Nieuwenhuizen, L., van Moort, I., Baker, R. I., O'Donnell, J. S., Cnossen, M. H., Heubel-Moenen, F. C. J. I., & BDUC-iN Study group (2024). Bleeding disorder of unknown cause: an illustrated review on current practice, knowledge gaps, and future perspectives. Research and practice in thrombosis and haemostasis, 8(8), Article 102625. https://doi.org/10.1016/j.rpth.2024.102625
- Meijs, D. A. M., Wynants, L., van Kuijk, S. M. J., Scheeren, C. I. E., Hana, A., Mehagnoul-Schipper, J., Stessel, B., Vander Laenen, M., Cox, E. G. M., Sels, J. W. E. M., Smits, L. J. M., Bickenbach, J., Mesotten, D., van der Horst, I. C. C., Marx, G., van Bussel, B. C. T., CoDaP Investigators, Heijnen, N., Mulder, M., ... Ghossein, C. (2024). Boosting the accuracy of existing models by updating and extending: using a multicenter COVID-19 ICU cohort as a proxy. Scientific Reports, 14(1), Article 26344. https://doi.org/10.1038/s41598-024-70333-6
- Rijvers, L., Rijpma, S. R., van Wetten, H. B., Henskens, Y. M. C., & Stroobants, A. K. (2024). International normalized ratio measurement during perioperative anticoagulation bridging with low-molecular-weight heparin in patients undergoing heart valve replacement surgery. Research and practice in thrombosis and haemostasis, 8(8), Article 102616. https://doi.org/10.1016/j.rpth.2024.102616
- Heuvelings, D. J. I., van der Horst, J., Pelzer, F., Aarts, F., & Engelen, S. (2024). Massive Localized Lymphedema, Wound Care Without Major Surgical Excision: A Case Report. Advances in Skin and Wound Care, 37(11-12), 1-6. https://doi.org/10.1097/ASW.0000000000000222
- Battaglini, D., Kelly, T. L., Griffee, M., Fanning, J., Premraj, L., Whitman, G., Porto, D. B., Arora, R., Thomson, D., Pelosi, P., White, N. M., Bassi, G. L., Suen, J., Fraser, J. F., Robba, C., Cho, S. M., Al-Dabbous, T., Alfoudri, H., Shamsah, M., ... Mariani, S. (2024). Stroke in critically ill patients with respiratory failure due to COVID-19: Disparities between low-middle and high-income countries. Heart & Lung, 68, 131-144. https://doi.org/10.1016/j.hrtlng.2024.06.015
- Willers, V., Krumeich, J. R. L., Hulshof, A.-M., Buise, M. P., van der Horst, I. C. C., Henskens, Y. M. C., van Bussel, B. C. T., & Kuiper, G. J. A. J. M. (2024). Comparison of the Quantra QPlus and ROTEM Goal-Directed Transfusion Protocols in Cardiothoracic Surgery Patients: A Prospective Observational Study. Journal of Cardiothoracic and Vascular Anesthesia, 38(11), 2559-2566. https://doi.org/10.1053/j.jvca.2024.07.046
- Bari, G., Mariani, S., van Bussel, B. C. T., Ravaux, J., Di Mauro, M., Schaefer, A., Khalil, J., Pozzi, M., Botta, L., Pacini, D., Boeken, U., Samalavicius, R., Bounader, K., Hou, X., Bunge, J. J. H., Buscher, H., Salazar, L., Meyns, B., Mazeffi, M., ... Post-Cardiotomy Extracorporeal Life Support (PELS-1) Investigators (2024). Post-cardiotomy extracorporeal life support: A cohort of cannulation in the general ward. Artificial Organs, 48(11), 1355-1365. https://doi.org/10.1111/aor.14818
- Susanna, C., van Dijk, N., de Jongh, W., Verberght, H., van Mook, W., Bollen, J., & van Bussel, B. (2024). Promising Results of Kidney Transplantation From Donors Following Euthanasia During 10-Year Follow-Up: A Nationwide Cohort Study. Transplant International, 37, Article 13142. https://doi.org/10.3389/ti.2024.13142
- Monard, A., Castoldi, E., De Simone, I., Wichapong, K., van Duijl, T., van den Biggelaar, M., Spada, S., van Doorn, W., Hellenbrand, D., van der Meijden, P., Swieringa, F., Stork, A., ten Cate, H., Beckers, E., Heubel-Moenen, F., & Henskens, Y. (2024). Case Report: Laboratory detection of a thrombotic tendency in a family with hypodysfibrinogenemia and a novel FGG mutation. Frontiers in Cardiovascular Medicine, 11, Article 1488602. https://doi.org/10.3389/fcvm.2024.1488602
- Rigby, A., Albisetti, M., Favaloro, E. J., Koenen, R. R., Langer, F., Lip, G. Y. H., Ruehl, H., & Weber, C. (2024). Reflections on World Thrombosis Day 2024. Thrombosis and Haemostasis, 125(1), 3-6. https://doi.org/10.1055/s-0044-1791650
- Bunge, J. J. H., Mariani, S., Meuwese, C., van Bussel, B. C. T., Di Mauro, M., Wiedeman, D., Saeed, D., Pozzi, M., Loforte, A., Boeken, U., Samalavicius, R., Bounader, K., Hou, X., Buscher, H., Salazar, L., Meyns, B., Herr, D., Matteucci, S., Sponga, S., ... Post-Cardiotomy Extracorporeal Life Support (PELS-1) Investigators (2024). Characteristics and Outcomes of Prolonged Venoarterial Extracorporeal Membrane Oxygenation After Cardiac Surgery: The Post-Cardiotomy Extracorporeal Life Support (PELS-1) Cohort Study. Critical Care Medicine, 52(10), e490-e502. https://doi.org/10.1097/CCM.0000000000006349
- Mussert, C., Monard, A., & Heubel-Moenen, F. (2024). How to treat patients with bleeding disorder of unknown cause?Research and practice in thrombosis and haemostasis, 8(7), Article 102585. https://doi.org/10.1016/j.rpth.2024.102585
- Visser, C., Berentschot, J. C., de Jong, C. M. M., Antoni, M. L., Bek, L. M., van den Berg-Emons, R. J. G., van den Borst, B., ten Cate, H., ten Cate-Hoek, A. J., Braeken, D. C. W., Geelhoed, J. J. M., Heijenbrok-Kal, M. H., van Kuijk, S. M. J., Kroft, L. J. M., Leentjens, J., Roukens, A. H. E., Cannegieter, S. C., Klok, F. A., Kruip, M. J. H. A., ... Dutch COVID & Thrombosis Coalition (2024). The impact of pulmonary embolism on health outcomes of COVID-19 at 3 months after hospitalization. Research and practice in thrombosis and haemostasis, 8(7), Article e102573. https://doi.org/10.1016/j.rpth.2024.102573
- Gentier, A., Aizaz, M., Halder, M., Florea, A., Dijkgraaf, I., Mottaghy, F. M., Hackeng, T., & Kooi, M. E. (2024). Why Current Detection of Vascular Calcification Falls Short and How to Improve on It. TH open : companion journal to thrombosis and haemostasis, 08(04), e340-e349. https://doi.org/10.1055/a-2495-1444




