Publications
- 2025
- de Kok, J. W. T. M., van Bussel, B. C. T., van der Horst, I. C. C., & van Rosmalen, F. (2025). From Introducing Table 0 to Forgetting Figure 1: It is time for a reporting guideline for publishing with real-world clinical data. Author's reply. Journal of Clinical Epidemiology, 179, Article 111656. https://doi.org/10.1016/j.jclinepi.2024.111656
- Truijen, S., Austen, S., Magdelijns, F., Boonen, A., & van Onna, M. (2025). Getting prepared for the silver wave: challenges in conducting rheumatic and musculoskeletal disease research in older adults. RMD Open, 11(1), Article e005280. https://doi.org/10.1136/rmdopen-2024-005280
- ten Cate-Hoek, A. J. (2025). Konservative Behandlung zur Verhinderung des postthrombotischen Syndroms in der aktuellen klinischen Praxis. Phlebologie, 54(1), 15-25. https://doi.org/10.1055/a-2227-5424
- Cramer, I. C., Cox, E. G. M., de Kok, J. W. T. M., Koeze, J., Visser, M., Bouma, H. R., Dekker, A. D. B., van der Horst, I. C. C., Bouwman, R. A., & van Bussel, B. C. T. (2025). Quantification of facial cues for acute illness: a systematic scoping review. Intensive Care Medicine Experimental, 13(1), Article 17. https://doi.org/10.1186/s40635-025-00719-x
- Wintjens, M. S. J. N., Aydeniz, E., van Rosmalen, F., Driessen, R. G. H., Hulshof, A.-M., Bergmans, D. C. J. J., van Kuijk, S. M. J., van der Horst, I. C. C., van Bussel, B. C. T., MaastrICCht Collaborators, Bels, J., van de Berg, T., Brandts, L., van Gassel, R., Ghossein, M., Heines, S., de Jongh, S., van der Knaap, N., Meijs, D., ... Schellens, J. (2025). The Maastricht Intensive Care COVID Cohort: A Critical Appraisal of the Predefined Research Questions. Critical care explorations, 7(2), Article e1211. https://doi.org/10.1097/CCE.0000000000001211
- Smit, E. R., Kreft, I. C., Camilleri, E., Burggraaf-van Delft, J. L. I., van Rein, N., van Vlijmen, B. J. M., Hulshof, A.-M., van Bussel, B. C. T., van Rosmalen, F., van der Zwaan, C., van de Berg, T., Henskens, Y., ten Cate, H., Coutinho, J. M., Kruip, M. J. H. A., Eikenboom, J. J. C., Hoogendijk, A. J., Cannegieter, S. C., van den Biggelaar, M., ... Dutch COVID & Thrombosis Coalition (2025). Exploration of the plasma proteomic profile of patients at risk of thromboembolic events. Research and practice in thrombosis and haemostasis, 9(2), Article e102713. https://doi.org/10.1016/j.rpth.2025.102713
- Isaacs, A., Zeemering, S., Winters, J., Batlle, M., Bidar, E., Boukens, B., Casadei, B., Chua, W., Crijns, H. J. G. M., Fabritz, L., Guasch, E., Hatem, S. N., Hermans, B., Kääb, S., Kawczynski, M., Maesen, B., Maessen, J., Mont, L., Sinner, M. F., ... Stoll, M. (2025). Lateral Atrial Expression Patterns Provide Insights into Local Transcription Disequilibrium Contributing to Disease Susceptibility. Circulation: Genomic and Precision Medicine, 18(1), Article e004594. https://doi.org/10.1161/CIRCGEN.124.004594
- van Kwawegen, C. B., Pastoor, H., Eikenboom, J., Fijnvandraat, K., Ypma, P., Heubel-Moenen, F. C. J. I., van Galen, K. P. M., Mauser-Bunschoten, E. P., Meijer, K., Schols, S. E. M., Cnossen, M. H., van der Bom, J. G., de Meris, J., Atiq, F., Kruip, M. J. H. A., Leebeek, F. W. G., & WiN Study Group (2025). Sexuality and bleeding in von Willebrand disease. Research and practice in thrombosis and haemostasis, 9(2), Article e102712. https://doi.org/10.1016/j.rpth.2025.102712
- Herrera-Rivero, M., Garvert, L., Horn, K., Löbner, M., Weitzel, E. C., Stoll, M., Lichtner, P., Teismann, H., Teumer, A., Van der Auwera, S., Völzke, H., Völker, U., Andlauer, T. F. M., Meinert, S., Heilmann-Heimbach, S., Forstner, A. J., Streit, F., Witt, S. H., Kircher, T., ... Berger, K. (2025). A meta-analysis of genome-wide studies of resilience in the German population. Molecular Psychiatry, 30(2), 497-505. Article e12439. https://doi.org/10.1038/s41380-024-02688-1
- Heines, S. J. H., de Jongh, S. A. M., de Jongh, F. H. C., Segers, R. P. J., Gilissen, K. M. H., van der Horst, I. C. C., van Bussel, B. C. T., & Bergmans, D. C. J. J. (2025). A novel positive end-expiratory pressure titration using electrical impedance tomography in spontaneously breathing acute respiratory distress syndrome patients on mechanical ventilation: an observational study from the MaastrICCht cohort. Journal of Clinical Monitoring and Computing, 39(1), 127-139. https://doi.org/10.1007/s10877-024-01212-8
- Bouwens, B. R. C., Magdeleyns, E., Thomassen, M. C. L. G. D., Bouwman, F. G., Suylen, D. P., Hackeng, T. M., & Koenen, R. R. (2025). Citrullination of tissue factor pathway inhibitor alpha by peptidylarginine deiminase 4 impairs its natural anticoagulant activity toward factors Xa and VIIa/tissue factor and reduces binding to its cofactor protein S. Journal of Thrombosis and Haemostasis, 23(2), 641-650. https://doi.org/10.1016/j.jtha.2024.11.009
- Ganar, K. A., Nandy, M., Turbina, P., Chen, C., Suylen, D., Nihoul, E., Pascoe, E. L., van der Beelen, S., Plaum, M., van den Bos, L., Koenraadt, C. J. M., Dijkgraaf, I., & Deshpande, S. (2025). Phase separation and ageing of glycine-rich protein from tick adhesive. Nature Chemistry, 17(2), 186-197. Article 490. https://doi.org/10.1038/s41557-024-01686-8
- Cox, E. G. M., Meijs, D. A. M., Wynants, L., Sels, J.-W. E. M., Koeze, J., Keus, F., Bos-van Dongen, B., van der Horst, I. C. C., & van Bussel, B. C. T. (2025). "The definition of predictor and outcome variables in mortality prediction models: a scoping review and quality of reporting study". Journal of Clinical Epidemiology, 178, Article 111605. https://doi.org/10.1016/j.jclinepi.2024.111605
- Koenen, R. R. (2025). TH Open-Editor's Highlights of 2024. TH open : companion journal to thrombosis and haemostasis, 09, Article a25134445. https://doi.org/10.1055/a-2513-4445
- Ten Cate, H. (2025). The wonders of anticoagulation. Frontiers in Cardiovascular Medicine, 11, Article 1517109. https://doi.org/10.3389/fcvm.2024.1517109
- Shaw, J. R., Nopp, S., Stavik, B., Youkhana, K., Michels, A. L., Kennes, S., Rak, J., & ten Cate, H. (2025). Thrombosis, Translational Medicine, and Biomarker Research: Moving the Needle. Journal of the American Heart Association, 14(1), Article e038782. https://doi.org/10.1161/JAHA.124.038782
- De Caterina, R., Ten Cate, H., & Pengo, V. (2025). Non-vitamin K oral anticoagulants in valvular heart disease before surgery: a tale of bridging vs. no bridging. European Heart Journal, 46(1), 35-37. https://doi.org/10.1093/eurheartj/ehae615
- Xin, X., & Koenen, R. R. (2025). Assessing platelet-derived extracellular vesicles for potential as therapeutic targets in cardiovascular diseases. Expert Opinion on Therapeutic Targets, 29(1-2), 17-28. https://doi.org/10.1080/14728222.2025.2454617
- Ceulemans, A., Barakzie, A., Spronk, H. M. H., de Maat, M. P. M., van Beusekom, H. M. M., Taha, A., Emmer, B. J., Roos, Y. B. W. E. M., Dippel, D. W. J., Majoie, C. B. L. M., van Zwam, W. H., ten Cate, H., van Oostenbrugge, R. J., & Nagy, M. (2025). Association between coagulation activity and clinical and imaging outcomes in acute ischemic stroke patients - A sub-study of the MR CLEAN NO-IV trial. Thrombosis Research, 245, Article 109212. https://doi.org/10.1016/j.thromres.2024.109212
- Albu, E., Gao, S., Stijnen, P., Rademakers, F. E., van Bussel, B. C. T., Collyer, T., Hernandez-Boussard, T., Wynants, L., & Van Calster, B. (2025). Challenges and Recommendations for Electronic Health Records Data Extraction and Preparation for Dynamic Prediction Modeling in Hospitalized Patients: Practical Guide and Tutorial. Journal of Medical Internet Research, 27(1), Article e73987. https://doi.org/10.2196/73987
- van Mourik, D. J. M., Jansen, V. L. B. I., Coppens, M., Middeldorp, S., ten Cate, H., Buller, H. R., Spronk, H. M. H., Nagy, M., & van Mens, T. E. (2025). Intrinsic pathway activation in patients with antiphospholipid syndrome and healthy controls. Research and practice in thrombosis and haemostasis, 9(1), Article 102694. https://doi.org/10.1016/j.rpth.2025.102694
- Mozaffari, S., Moen, A., Ng, C. Y., Nicolaes, G. A. F., & Wichapong, K. (2025). Structural bioinformatics for rational drug design. Research and practice in thrombosis and haemostasis, 9(1), Article e102691. https://doi.org/10.1016/j.rpth.2025.102691
- Hupperetz, R., & Ten Cate-Hoek, A. (2025). The Postthrombotic syndrome, where are we now?Vasa-European Journal of Vascular Medicine, 54(1), 7-19. https://doi.org/10.1024/0301-1526/a001156
- Barakzie, A., Jansen, G. A. J., Cavalcante, F., Nagy, M., Dippel, D. W. J., van der Lugt, A., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Cate, H. T., de Maat, M. P. M., & CONTRAST Consortium (2025). Association of primary and secondary hemostasis biomarkers with acute ischemic stroke outcome in patients undergoing thrombectomy, with or without thrombolytics: post hoc analysis of the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands-NO IV. Journal of Thrombosis and Haemostasis, 23(1), 235-247. https://doi.org/10.1016/j.jtha.2024.10.008
- Monegatti, S., Martinelli, N., Friso, S., Spronk, H. M., & Ten Cate, H. (2025). Mechanisms and management of thrombosis in cancer: focus on gastrointestinal malignancies. Journal of Pharmacology and Experimental Therapeutics, 392(1), Article 100018. https://doi.org/10.1124/jpet.124.002203
- Meex, S. J. R., & Aakre, K. M. (2025). Personalized ranges for blood-test results enable precision diagnostics. Nature, 637(8045), 279-280. https://doi.org/10.1038/d41586-024-03854-9
- Sileo, A., Gabetti, S., Gulan, A. C., Cervenka, I., Zhang, C., Mingels, A., Milan, G., Massai, D., & Marsano, A. (2025). Asymmetric biphasic electric stimulation supports cardiac maturation and functionality. Journal of Tissue Engineering, 16, Article 20417314251393556. https://doi.org/10.1177/20417314251393556
- Kuc, S., Wijnen, P., Erckens, R., Gijs, M., Webers, C. A. B., Bekers, O., & Drent, M. (2025). Clinical Patterns of Sarcoidosis Patients with and without Uveitis: Insights from a Dutch Sarcoidosis Centre. Ocular Immunology and Inflammation, 33(1), 125-132. https://doi.org/10.1080/09273948.2024.2369931
- Wiedemann, N., Korte-De Boer, D. D., Richter, M., Weijer, S. V. D., Buhre, C., Eggert, F. A. M., Aarnoudse, S., Grevendonk, L., Röber, S., Remie, C. M. E., Buhre, W., Henry, R., & Born, J. (2025). COVID-BLUeS - A Prospective Study on the Value of AI in Lung Ultrasound Analysis. IEEE Journal of Biomedical and Health Informatics, 29(9), 6301-6310. https://doi.org/10.1109/JBHI.2025.3543686
- Rocca, B., & Cate, H. T. (2025). Factor XI and Atrial Fibrillation: A Mismatched Pairing?European Cardiology Review, 20, Article e08. https://doi.org/10.15420/ecr.2024.61
- Spoormans, E. M., Thevathasan, T., Van Royen, N., Zwinderman, A. H., Freund, A., Thiele, H., Ziesemer, K., Desch, S., Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., ... COACT and TOMAHAWK Trials Investigators (2025). One-Year Outcomes of Coronary Angiography After Out-of-Hospital Cardiac Arrest Without ST Elevation: An Individual Patient Data Meta-Analysis. JAMA Cardiology, 10(8), 779-786. https://doi.org/10.1001/jamacardio.2025.1194
- Bari, G., Mariani, S., van Bussel, B. C. T., Di Mauro, M., Conci, L., Saeed, D., Pozzi, M., Loforte, A., Boeken, U., Samalavicius, R., Bounader, K., Hou, X., J H Bunge, J., Buscher, H., Salazar, L., Meyns, B., Mazzeffi, M., Matteucci, S., Sponga, S., ... PELS Investigators (2025). Post-Cardiotomy Extracorporeal Life Support Following Aortic Surgery. Asaio Journal. Advance online publication. https://doi.org/10.1097/MAT.0000000000002619
- Hesselink, G., Verhage, R., Westerhof, B., Verweij, E., Fuchs, M., Janssen, I., van der Meer, C., van der Horst, I. C. C., de Jong, P., van der Hoeven, J. G., & Zegers, M. (2025). Reducing administrative burden by implementing a core set of quality indicators in the ICU: a multicentre longitudinal intervention study. BMJ Quality and Safety, 34(3), 157-165. https://doi.org/10.1136/bmjqs-2024-017481
- 2024
- Wortel, S. A., Bakhshi-Raiez, F., Abu-Hanna, A., Dongelmans, D. A., Keizer, N. F. D., Houwink, A., Dijkhuizen, A., Draisma, A., Rijkeboer, A., Cloïn, A., Meijer, A. D., Reidinga, A., Festen-Spanjer, B., van Bussel, B., Eikemans, B., Jacobs, C., Moolenaar, D., Ramnarain, D., Koning, D., ... Dutch COVID-19 Research Consortium (2024). Long-term mortality of Dutch COVID-19 patients admitted to the intensive care medicine: a retrospective analysis from a national quality registry. Critical Care Science, 36, Article e202400251en. https://doi.org/10.62675/2965-2774.20240251-en
- Velt, M. J. H., Crijns, H. J. G. M., van Gelder, I. C., Linz, D., van de Lande, M. E., Ten Cate, H., Spronk, H. M. H., de Melis, M., Rienstra, M., & Mulder, B. A. (2024). Dynamic biomarker profiles in patients with paroxysmal atrial fibrillation: Assessing the differences between sinus rhythm and acute atrial fibrillation episode. International Journal of Cardiology, 417, Article 132526. https://doi.org/10.1016/j.ijcard.2024.132526
- de Laat-Kremers, R., Huang, S., ten Cate, H., Ninivaggi, M., de Laat, B., & Devreese, K. (2024). Interpreting high levels of unfolded Von Willebrand Factor in patients with the antiphospholipid syndrome. Frontiers in Immunology, 15, Article 1514433. https://doi.org/10.3389/fimmu.2024.1514433
- Reyat, J. S., Sommerfeld, L. C., O'Reilly, M., Cardoso, V. R., Thiemann, E., Khan, A. O., O'Shea, C., Harder, S., Müller, C., Barlow, J., Stapley, R. J., Chua, W., Kabir, S. N., Grech, O., Hummel, O., Hübner, N., Kääb, S., Mont, L., Hatem, S. N., ... Fabritz, L. (2024). PITX2 deficiency leads to atrial mitochondrial dysfunction. Cardiovascular Research, 120(15), 1907-1923. https://doi.org/10.1093/cvr/cvae169
- Hansildaar, R., Raadsen, R., Gerritsen, M., Nagy, M., Dijkshoorn, B., Spronk, H. M. H., Ten Cate, H., & Nurmohamed, M. T. (2024). Comparative Analysis of Coagulation Activation in Rheumatoid Arthritis Patients Treated With TNF Inhibitors Versus JAK Inhibitors: A Longitudinal Study. Journal of Clinical Rheumatology, 30(8), e166-e171. Article 002136. https://doi.org/10.1097/RHU.0000000000002136
- Baaten, C. C. F. M. J., Nagy, M., Spronk, H. M. H., Ten Cate, H., & Kietselaer, B. L. J. H. (2024). NETosis in Cardiovascular Disease: An Opportunity for Personalized Antithrombotic Treatments?Arteriosclerosis Thrombosis and Vascular Biology, 44(12), 2366-2370. https://doi.org/10.1161/ATVBAHA.124.320150
- Lemmens, T. P., Luo, Q., Wielders, S. J. H., Scheijen, J. L. J. M., Al-Nasiry, S., Koenen, R. R., Wenzel, P., & Cosemans, J. M. E. M. (2024). Platelet collagen receptors and their role in modulating platelet adhesion patterns and activation on alternatively processed collagen substrates. Thrombosis Research, 244, Article 109201. https://doi.org/10.1016/j.thromres.2024.109201
- Jooss, N. J., Diender, M. G., Fernandez, D. I., Huang, J., Heubel-Moenen, F. C. J., van der Veer, A., Kuijpers, M. J. E., Poulter, N. S., Henskens, Y. M. C., te Loo, M., & Heemskerk, J. W. M. (2024). Restraining of glycoprotein VI- and integrin α2β1-dependent thrombus formation by platelet PECAM1. Cellular and Molecular Life Sciences, 81(1), Article 44. https://doi.org/10.1007/s00018-023-05058-2
- Chai, J., Wu, J., Yang, J., Ye, T., Gao, Y., Zeng, B., Xiong, W., Kotsyfakis, M., Dijkgraaf, I., Liu, J., Chen, X., & Xu, X. (2024). Cath-HG improves the survival rates and symptoms in LPS-induced septic mice due to its multifunctional properties. International Immunopharmacology, 143(Pt 1), Article 113332. https://doi.org/10.1016/j.intimp.2024.113332
- Mariani, S., Ravaux, J. M., van Bussel, B. C. T., De Piero, M. E., van Kruijk, S. M. J., Schaefer, A.-K., Wiedemann, D., Saeed, D., Pozzi, M., Loforte, A., Boeken, U., Samalavicius, R., Bounader, K., Hou, X., Bunge, J. J. H., Buscher, H., Salazar, L., Meyns, B., Mazzeffi, M. A., ... Post-Cardiotomy Extracorporeal Life Support (PELS-1) Investigators (2024). Features and outcomes of female and male patients requiring postcardiotomy extracorporeal life support. Journal of Thoracic and Cardiovascular Surgery, 168(6), 1701-1711.e30. https://doi.org/10.1016/j.jtcvs.2024.04.033
- de Jong, M. J., Saadan, H., van der Hooft, B. H. M., Hellenbrand, D. L. S., Brüggemann, R. A. G., Ten Cate, H., van Kuijk, S. M. J., van Geel, R. M. J. M., Henskens, Y. M. C., Winckers, K., & Magdelijns, F. J. H. (2024). Intra-Individual Variability of Direct Oral Anticoagulant Levels in Frail Older Patients upon, during, and after Acute Hospitalization: the DOAC-FRAIL Study. Journal of the American Medical Directors Association, 25(12), Article 105280. https://doi.org/10.1016/j.jamda.2024.105280
- Hupperetz, R. D., Iding, A. F., van Laanen, J., Brans, R., Notten, P., Tick, L. W., Vleming, L.-J., Jie, A., Planken, N., Wittens, C. H. A., Ten Cate, H., & Ten Cate-Hoek, A. J. (2024). Patency and reflux in relation to post-thrombotic syndrome: a subanalysis of the Ultrasound-Accelerated Catheter-Directed Thrombolysis Versus Anticoagulation for the Prevention of Post-Thrombotic Syndrome trial. Journal of Thrombosis and Haemostasis, 22(12), 3552-3561. https://doi.org/10.1016/j.jtha.2024.08.022
- Zou, J., Zhang, P., Solari, F. A., Schönichen, C., Provenzale, I., Mattheij, N. J. A., Kuijpers, M. J. E., Rauch, J. S., Swieringa, F., Sickmann, A., Zieger, B., Jurk, K., & Heemskerk, J. W. M. (2024). Suppressed ORAI1-STIM1-dependent Ca2+ entry by protein kinase C isoforms regulating platelet procoagulant activity. Journal of Biological Chemistry, 300(12), Article 107899. https://doi.org/10.1016/j.jbc.2024.107899
- Fernández, D. I., Troitiño, S., Sobota, V., Tullemans, B. M. E., Zou, J., van den Hurk, H., García, Á., Honarnejad, S., Kuijpers, M. J. E., & Heemskerk, J. W. M. (2024). Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics. Scientific Reports, 14(1), Article 6229. https://doi.org/10.1038/s41598-024-56799-4
- Boschetti, L., Nilius, H., Ten Cate, H., Wuillemin, W. A., Faes, L., Bossuyt, P. M., Bachmann, L. M., & Nagler, M. (2024). Design-related bias in studies investigating diagnostic tests for venous thromboembolic diseases: a systematic review and meta-analysis. Frontiers in Cardiovascular Medicine, 11, Article 1420000. https://doi.org/10.3389/fcvm.2024.1420000




