• 2022
    • Seelig, J., Chu, G., Trinks-Roerdink, E. M., Pisters, R., de Vries, T. A. C., Ten Cate, H., Geersing, G.-J., Rutten, F. H., Huisman, M. V., & Hemels, M. E. W. (2022). Unequal prescription of anticoagulants among females and males with atrial fibrillation and similar stroke risk: Should we omit sex category from the CHA2DS2-VASc score?Heart Rhythm, 19(5), 860-861. https://doi.org/10.1016/j.hrthm.2022.01.014
    • Limperger, V., Torge, A., Kiesau, B., Langer, F., Kenet, G., Mesters, R., Juhl, D., Stoll, M., Shneyder, M., Kowalski, D., Bajorat, T., Rocke, A., Kuta, P., Lasarow, L., Spengler, D., Junker, R., & Nowak-Göttl, U. (2022). Validation of a predictive model for identifying an increased risk for recurrence in adolescents and young adults with a first provoked thromboembolism. Blood Cells Molecules and Diseases, 94, Article 102651. https://doi.org/10.1016/j.bcmd.2022.102651
    • van Herpt, T. T. W., Timmermans, S. A. M. E. G., van Mook, W. N. K. A., van Bussel, B. C. T., van der Horst, I. C. C., Maessen, J. G., Natour, E., van Paassen, P., & Heuts, S. (2022). Postsurgical Thrombotic Microangiopathy and Deregulated Complement. Journal of Clinical Medicine, 11(9), Article 2501. https://doi.org/10.3390/jcm11092501
    • Leberzammer, J., Agten, S. M., Blanchet, X., Duan, R., Ippel, H., Megens, R. T. A., Schulz, C., Aslani, M., Duchene, J., Döring, Y., Jooss, N. J., Zhang, P., Brandl, R., Stark, K., Siess, W., Jurk, K., Heemskerk, J. W. M., Hackeng, T. M., Mayo, K. H., ... von Hundelshausen, P. (2022). Targeting platelet-derived CXCL12 impedes arterial thrombosis. Blood, 139(17), 2691-2705. https://doi.org/10.1182/blood.2020010140
    • Stultiens, J. M. G., Top, W. M. C., Kimenai, D. M., Lehert, P., Bekers, O., Stehouwer, C. D. A., Kooy, A., & Meex, S. J. R. (2022). Metformin and high-sensitivity cardiac troponin I and T trajectories in type 2 diabetes patients: a post-hoc analysis of a randomized controlled trial. Cardiovascular Diabetology, 21(1), Article 49. https://doi.org/10.1186/s12933-022-01482-z
    • Witten, A., Martens, L., Schäfer, A.-C., Troidl, C., Pankuweit, S., Vlacil, A.-K., Oberoi, R., Schieffer, B., Grote, K., Stoll, M., & Markus, B. (2022). Monocyte subpopulation profiling indicates CDK6-derived cell differentiation and identifies subpopulation-specific miRNA expression sets in acute and stable coronary artery disease. Scientific Reports, 12(1), Article 5589. https://doi.org/10.1038/s41598-022-08600-7
    • Denessen, E. J. S., Van den Kerkhof, D. L., Jeurissen, M. L. J., Wetzels, R. J. H., Verhezen, P. W. M., & Henskens, Y. M. C. (2022). Determining the Optimal Storage Time and Temperature for Performing Platelet Function Assays and Global Hemostasis Assays. Platelets, 33(3), 416-424. https://doi.org/10.1080/09537104.2021.1934666
    • Karel, M. F. A., Tullemans, B. M. E., D'Italia, G., Lemmens, T. P., Claushuis, T. A. M., Kuijpers, M. J. E., & Cosemans, J. M. E. M. (2022). Corrigendum to "The effect of Bruton's tyrosine kinase inhibitor ibrutinib on atherothrombus formation under stenotic flow conditions" [Thromb. Res. 212 (2022) 72-80]. Thrombosis Research, 213, 113-113. https://doi.org/10.1016/j.thromres.2022.03.012
    • Mesotten, D., Meijs, D. A. M., van Bussel, B. C. T., Stessel, B., Mehagnoul-Schipper, J., Hana, A., Scheeren, C. I. E., Strauch, U., van de Poll, M. C. G., Ghossein-Doha, C., Buhre, W. F. F. A., Bickenbach, J., Vander Laenen, M., Marx, G., van der Horst, I. C. C., & COVID Data Platform (CoDaP) Investigators (2022). Differences and Similarities Among COVID-19 Patients Treated in Seven ICUs in Three Countries Within One Region: An Observational Cohort Study. Critical Care Medicine, 50(4), 595-606. https://doi.org/10.1097/CCM.0000000000005314
    • Karel, M. F. A., Tullemans, B. M. E., D'Italia, G., Lemmens, T. P., Claushuis, T. A. M., Kuijpers, M. J. E., & Cosemans, J. M. E. M. (2022). The effect of Bruton's tyrosine kinase inhibitor ibrutinib on atherothrombus formation under stenotic flow conditions. Thrombosis Research, 212, 72-80. https://doi.org/10.1016/j.thromres.2022.02.020
    • Dolleman, S. C., Agten, S. M., Spronk, H. M. H., Hackeng, T. M., Bos, M. H. A., Versteeg, H. H., van Zonneveld, A. J., & de Boer, H. C. (2022). Thrombin in complex with dabigatran can still interact with PAR-1 via exosite-I and instigate loss of vascular integrity. Journal of Thrombosis and Haemostasis, 20(4), 996-1007. https://doi.org/10.1111/jth.15642
    • Alaour, B., Omland, T., Torsvik, J., Kaier, T. E., Sylte, M. S., Strand, H., Quraishi, J., McGrath, S., Williams, L., Meex, S., Redwood, S., Marber, M., & Aakre, K. M. (2022). Biological variation of cardiac myosin-binding protein C in healthy individuals. Clinical Chemistry and Laboratory Medicine, 60(4), 576-583. https://doi.org/10.1515/cclm-2021-0306
    • Neradova, A., Wasilewski, G., Prisco, S., Leenders, P., Caron, M., Welting, T., van Rietbergen, B., Kramann, R., Floege, J., Vervloet, M. G., & Schurgers, L. J. (2022). Combining phosphate binder therapy with vitamin K2 inhibits vascular calcification in an experimental animal model of kidney failure. Nephrology Dialysis Transplantation, 37(4), 652-662. https://doi.org/10.1093/ndt/gfab314
    • Linschoten, M., Uijl, A., Schut, A., Jakob, C. E. M., Romao, L. R., Bell, R. M., McFarlane, E., Stecher, M., Zondag, A. G. M., van Iperen, E. P. A., Hermans-van Ast, J. F., Lea, N. C., Schaap, J., Jewbali, L. S., Smits, P. C., Patel, R. S., Aujayeb, A., van Smeden, M., Siebelink, H. J., ... Raafs, A. (2022). Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries. European Heart Journal, 43(11), 1104-1120. https://doi.org/10.1093/eurheartj/ehab656
    • Hafeez, S., Ooi, H. W., Suylen, D., Duimel, H., Hackeng, T. M., van Blitterswijk, C., & Baker, M. B. (2022). Desymmetrization via Activated Esters Enables Rapid Synthesis of Multifunctional Benzene-1,3,5-tricarboxamides and Creation of Supramolecular Hydrogelators. Journal of the American Chemical Society, 144(9), 4057-4070. https://doi.org/10.1021/jacs.1c12685
    • Henkens, M. T. H. M., Raafs, A. G., Verdonschot, J. A. J., Linschoten, M., van Smeden, M., Wang, P., van der Hooft, B. H. M., Tieleman, R., Janssen, M. L. F., Ter Bekke, R. M. A., Hazebroek, M. R., van der Horst, I. C. C., Asselbergs, F. W., Magdelijns, F. J. H., Heymans, S. R. B., & CAPACITY-COVID collaborative consortium (2022). Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study. BMC Geriatrics, 22(1), Article 184. https://doi.org/10.1186/s12877-021-02673-1
    • Poelman, H., Ippel, H., Gurkan, B., Boelens, R., Vriend, G., van 't Veer, C., Lutgens, E., & Nicolaes, G. A. F. (2022). Structural anomalies in a published NMR-derived structure of IRAK-M. Journal of Molecular Graphics & Modelling, 111, Article 108061. https://doi.org/10.1016/j.jmgm.2021.108061
    • Dauwerse, S., ten Cate, H., Spronk, H. M. H., & Nagy, M. (2022). The Composition and Physical Properties of Clots in COVID-19 Pathology. Diagnostics, 12(3), Article 580. https://doi.org/10.3390/diagnostics12030580
    • Herrera-Rivero, M., Gandhi, S., Witten, A., Ghalawinji, A., Schotten, U., & Stoll, M. (2022). Cardiac chamber-specific genetic alterations suggest candidate genes and pathways implicating the left ventricle in the pathogenesis of atrial fibrillation. Genomics, 114(2), Article 110320. https://doi.org/10.1016/j.ygeno.2022.110320
    • Camaro, C., Bonnes, J. L., Adang, E. M., Spoormans, E. M., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J., van der Harst, P., van der Horst, I. C., Voskuil, M., ... van Royen, N. (2022). Cost Analysis From a Randomized Comparison of Immediate Versus Delayed Angiography After Cardiac Arrest. Journal of the American Heart Association, 11(5), Article 022238. https://doi.org/10.1161/JAHA.121.022238
    • Grover, S. P., Coughlin, T., Fleifil, S. M., Posma, J. J. N., Spronk, H. H. M., Heitmeier, S., Owens, A. P., & Mackman, N. (2022). Effect of combining aspirin and rivaroxaban on atherosclerosis in mice. Atherosclerosis, 345, 7-14. https://doi.org/10.1016/j.atherosclerosis.2022.02.010
    • Simons, C. C. J. M., Offermans, N. S. M., Stoll, M., van den Brandt, P. A., & Weijenberg, M. P. (2022). Empirical Investigation of Genomic Clusters Associated with Height and the Risk of Postmenopausal Breast and Colorectal Cancer in the Netherlands Cohort Study. American Journal of Epidemiology, 191(3), 413-429. https://doi.org/10.1093/aje/kwab259
    • Heubel-Moenen, F. C. J. I., Brouns, S. L. N., Herfs, L., Boerenkamp, L. S., Jooss, N. J., Wetzels, R. J. H., Verhezen, P. W. M., Machiels, P., Megy, K., Downes, K., Heemskerk, J. W. M., Beckers, E. A. M., & Henskens, Y. M. C. (2022). Multiparameter platelet function analysis of bleeding patients with a prolonged platelet function analyser closure time. British Journal of Haematology, 196(6), 1388-1400. https://doi.org/10.1111/bjh.18003
    • Panova-Noeva, M., Wagner, B., Nagler, M., Koeck, T., Ten Cate, V., Eggebrecht, L., Prochaska, J. H., Meyer, I., Gerdes, C., Spronk, H. M., Lackner, K. J., Ten Cate, H., Leineweber, K., Heitmeier, S., Konstantinides, S., & Wild, P. S. (2022). Variation of platelet function in clinical phenotypes of acute venous thromboembolism - Results from the GMP-VTE project. Journal of Thrombosis and Haemostasis, 20(3), 705-715. https://doi.org/10.1111/jth.15595
    • Post, D. S., van der Veer, A., Schijns, O. E. M. G., Klinkenberg, S., Rijkers, K., Wagner, G. L., van Kranen-Mastenbroek, V. H. J. M., Willems, P. C. P. H., Verhezen, P. W. M., Beckers, E. A. M., Heubel-Moenen, F. C. J. I., & Henskens, Y. M. C. (2022). Assessment of need for hemostatic evaluation in patients taking valproic acid: A retrospective cross-sectional study. PLOS ONE, 17(2), Article e0264351. https://doi.org/10.1371/journal.pone.0264351
    • Hrdinova, J., Fernández, D. I., Ercig, B., Tullemans, B. M. E., Suylen, D. P. L., Agten, S. M., Jurk, K., Hackeng, T. M., Vanhoorelbeke, K., Voorberg, J., Reutelingsperger, C. P. M., Wichapong, K., Heemskerk, J. W. M., & Nicolaes, G. A. F. (2022). Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear. International journal of molecular sciences, 23(4), Article 2046. https://doi.org/10.3390/ijms23042046
    • Cosemans, J. M. E. M. (2022). Platelet-derived MMP-2 in the prevention of plaque formation: how many strokes is par?European Heart Journal, 43(6), 515–517. https://doi.org/10.1093/eurheartj/ehab665
    • De With, R. R., Artola Arita, V., Nguyen, B.-O., Linz, D., Ten Cate, H., Spronk, H., Schotten, U., van Zonneveld, A. J., Erküner, Ö., Bayón, M. A., Schmidt, A. S., Luermans, J. G. L. M., Crijns, H. J. G. M., Van Gelder, I. C., & Rienstra, M. (2022). Different circulating biomarkers in women and men with paroxysmal atrial fibrillation: results from the AF-RISK and RACE V studies. EP Europace, 24(2), 193-201. https://doi.org/10.1093/europace/euab179
    • Spoormans, E. M., Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J. W., Girbes, A. R. J., van der Harst, P., van der Horst, I. C. C., Voskuil, M., van der Heijden, J. J., ... Elbers, P. W. G. (2022). Targeted Temperature Management in Out-of-Hospital Cardiac Arrest With Shockable Rhythm: A Post Hoc Analysis of the Coronary Angiography After Cardiac Arrest Trial. Critical Care Medicine, 50(2), e129-e142. https://doi.org/10.1097/CCM.0000000000005271
    • Karel, M. F. A., Lemmens, T. P., Tullemans, B. M. E., Wielders, S. J. H., Gubbins, E., van Beurden, D., van Rijt, S., & Cosemans, J. M. E. M. (2022). Characterization of Atherosclerotic Plaque Coating for Thrombosis Microfluidics Assays. Cellular and Molecular Bioengineering, 15(1), 55-65. https://doi.org/10.1007/s12195-021-00713-9
    • Grabowski, K., Herlan, L., Witten, A., Qadri, F., Eisenreich, A., Lindner, D., Schadlich, M., Schulz, A., Subrova, J., Mhatre, K. N., Primessnig, U., Plehm, R., van Linthout, S., Escher, F., Bader, M., Stoll, M., Westermann, D., Heinzel, F. R., & Kreutz, R. (2022). Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension. Hypertension Research, 45(2), 292-307. https://doi.org/10.1038/s41440-021-00826-8
    • Maag, A., van Rein, N., Schuijt, T. J., Kopatz, W. F., Kruijswijk, D., Thomassen, S., Hackeng, T. M., Camire, R. M., van der Poll, T., Meijers, J. C. M., Bos, M. H. A., & van't Veer, C. (2022). Major bleeding during oral anticoagulant therapy associated with factor V activation by factor Xa. Journal of Thrombosis and Haemostasis, 20(2), 328-338. https://doi.org/10.1111/jth.15589
    • Brouns, S. L. N., Tullemans, B. M. E., Bulato, C., Perrella, G., Campello, E., Spiezia, L., van Geffen, J. P., Kuijpers, M. J. E., van Oerle, R., Spronk, H. M. H., van der Meijden, P. E. J., Simioni, P., & Heemskerk, J. W. M. (2022). Protein C or Protein S deficiency associates with paradoxically impaired platelet-dependent thrombus and fibrin formation under flow. Research and practice in thrombosis and haemostasis, 6(2), Article e12678. https://doi.org/10.1002/rth2.12678
    • Boswijk, E., de Ligt, M., Habets, M. F. J., Mingels, A. M. A., van Marken Lichtenbelt, W. D., Mottaghy, F. M., Schrauwen, P., Wildberger, J. E., & Bucerius, J. (2022). Resveratrol treatment does not reduce arterial inflammation in males at risk of type 2 diabetes: a randomized crossover trial. Nuklearmedizin, 61(01), 33-41. https://doi.org/10.1055/a-1585-7215
    • Fernandez, D. I., Provenzale, I., Cheung, H. Y. F., van Groningen, J., Tullemans, B. M. E., Veninga, A., Dunster, J. L., Honarnejad, S., van den Hurk, H., Kuijpers, M. J. E., & Heemskerk, J. W. M. (2022). Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation. iScience, 25(1), Article 103718. https://doi.org/10.1016/j.isci.2021.103718
    • Spaetgens, B., Nagy, M., & ten Cate, H. (2022). Antiplatelet Therapy in Patients With COVID-19-More Is Less?JAMA-Journal of the American Medical Association, 327(3), 223-224. https://doi.org/10.1001/jama.2021.23866
    • Heuts, S., Denessen, E. J. S., Daemen, J. H. T., Vroemen, W. H. M., Sels, J. W., Segers, P., Bekers, O., Hof, A. W. J. V., Maessen, J. G., van der Horst, I. C. C., & Mingels, A. M. A. (2022). Meta-Analysis Evaluating High-Sensitivity Cardiac Troponin T Kinetics after Coronary Artery Bypass Grafting in Relation to the Current Definitions of Myocardial Infarction. American Journal of Cardiology, 163, 25-31. https://doi.org/10.1016/j.amjcard.2021.09.049
    • Meijs, D. A. M., van Bussel, B. C. T., Stessel, B., Mehagnoul-Schipper, J., Hana, A., Scheeren, C. I. E., Peters, S. A. E., van Mook, W. N. K. A., van der Horst, I. C. C., Marx, G., Mesotten, D., Ghossein-Doha, C., CoDaP Investigators, Heijnen, N. F. L., Raafs, A., van Kuijk, S. M. J., Smits, L. J. M., Janssen, E. B. N. J., Mulder, M. M. G., ... Florack, M. C. D. M. (2022). Better COVID-19 Intensive Care Unit survival in females, independent of age, disease severity, comorbidities, and treatment. Scientific Reports, 12(1), Article 734. https://doi.org/10.1038/s41598-021-04531-x
    • Dongelmans, D. A., Termorshuizen, F., Brinkman, S., Bakhshi-Raiez, F., Arbous, M. S., de Lange, D. W., van Bussel, B. C. T., de Keizer, N. F., & Dutch COVID-19 Research Consortium (2022). Characteristics and outcome of COVID-19 patients admitted to the ICU: a nationwide cohort study on the comparison between the first and the consecutive upsurges of the second wave of the COVID-19 pandemic in the Netherlands. Annals of Intensive Care, 12(1), Article 5. https://doi.org/10.1186/s13613-021-00978-3
    • Simons, C. C. J. M., Schouten, L. J., Godschalk, R. W. L., Van Schooten, F. J., Stoll, M., Van Steen, K., van den Brandt, P. A., & Weijenberg, M. P. (2022). Polymorphisms in the mTOR-PI3K-Akt pathway, energy balance-related exposures and colorectal cancer risk in the Netherlands Cohort Study. Biodata Mining, 15(1), Article 2. https://doi.org/10.1186/s13040-021-00286-3
    • Heijnen, N. F. L., Hagens, L. A., van Schooten, F.-J., Bos, L. D. J., van der Horst, I. C. C., Mommers, A., Schultz, M. J., Smit, M. R., Bergmans, D. C. J. J., Smolinska, A., & Schnabel, R. M. (2022). Breath octane and acetaldehyde as markers for acute respiratory distress syndrome in invasively ventilated patients suspected to have ventilator-associated pneumonia. ERJ Open Research, 8(1), Article 00624. https://doi.org/10.1183/23120541.00624-2021
    • Kaczor, D. M., Kramann, R., Hackeng, T. M., Schurgers, L. J., & Koenen, R. R. (2022). Differential Effects of Platelet Factor 4 (CXCL4) and Its Non-Allelic Variant (CXCL4L1) on Cultured Human Vascular Smooth Muscle Cells. International Journal of Molecular Sciences, 23(2), Article 580. https://doi.org/10.3390/ijms23020580
    • Willems, L. H., Nagy, M., Ten Cate, H., Spronk, H. M. H., Groh, L. A., Leentjens, J., Janssen, N. A. F., Netea, M. G., Thijssen, D. H. J., Hannink, G., van Petersen, A. S., & Warle, M. C. (2022). Sustained inflammation, coagulation activation and elevated endothelin-1 levels without macrovascular dysfunction at 3 months after COVID-19. Thrombosis Research, 209, 106-114. https://doi.org/10.1016/j.thromres.2021.11.027
    • Navarro, S., Stegner, D., Nieswandt, B., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2022). Temporal Roles of Platelet and Coagulation Pathways in Collagen- and Tissue Factor-Induced Thrombus Formation. International journal of molecular sciences, 23(1), Article 358. https://doi.org/10.3390/ijms23010358
    • Heuts, S., van der Horst, I. C. C., & Mingels, A. (2022). Towards an improved definition of periprocedural myocardial infarction: The role of high-sensitivity cardiac troponins. Journal of Cardiac Surgery, 37(1), 162-164. https://doi.org/10.1111/jocs.16107
    • Tullemans, B. M. E., Fernandez, D. I., Veninga, A., Baaten, C. C. F. M. J., Peters, L. J. F., Aarts, M. J. B., Eble, J. A., Campello, E., Spiezia, L., Simioni, P., van der Vorst, E. P. C., van der Meijden, P. E. J., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2022). Tyrosine Kinase Inhibitor Sunitinib Delays Platelet-Induced Coagulation: Additive Effects of Aspirin. Thrombosis and Haemostasis, 122(01), 92-104. https://doi.org/10.1055/s-0041-1730312
    • Uengwetwanit, T., Chutiwitoonchai, N., Wichapong, K., & Karoonuthaisiri, N. (2022). Identification of novel SARS-CoV-2 RNA dependent RNA polymerase (RdRp) inhibitors: From in silico screening to experimentally validated inhibitory activity. Computational and Structural Biotechnology Journal, 20, 882-890. https://doi.org/10.1016/j.csbj.2022.02.001
    • Vignoli, A., Gamba, S., van der Meijden, P. E. J., Marchetti, M., Russo, L., Tessarolo, S., Giaccherini, C., Swieringa, F., Cate, H. T., Finazzi, G., Heemskerk, J. W. M., & Falanga, A. (2022). Increased platelet thrombus formation under flow conditions in whole blood from polycythaemia vera patients. Blood Transfusion, 20(2), 143-151. https://doi.org/10.2450/2021.0456-20