• 2022
    • Reijrink, M., van Ark, J., Lexis, C. P. H., Visser, L. M., Lodewijk, M. E., van der Horst, I. C. C., Zeebregts, C. J., van Goor, H., de Jager, S. C. A., Pasterkamp, G., Wolffenbuttel, B. H. R., & Hillebrands, J. L. (2022). Increased frequency of proangiogenic tunica intima endothelial kinase 2 (Tie2) expressing monocytes in individuals with type 2 diabetes mellitus. Cardiovascular Diabetology, 21(1), Article 72. https://doi.org/10.1186/s12933-022-01497-6
    • Jauch-Speer, S.-L., Herrera-Rivero, M., Ludwig, N., Véras De Carvalho, B. C., Martens, L., Wolf, J., Imam Chasan, A., Witten, A., Markus, B., Schieffer, B., Vogl, T., Rossaint, J., Stoll, M., Roth, J., & Fehler, O. (2022). C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9. Elife, 11, Article e75594. https://doi.org/10.7554/eLife.75594
    • Willems, R. A. L., Winckers, K., Biesmans, C., de Vos-Geelen, J., & ten Cate, H. (2022). Evolving data on cardiovascular complications in cancer. Thrombosis Research, 213, S87-S94. https://doi.org/10.1016/j.thromres.2022.01.003
    • Ghossein, M. A., Driessen, R. G. H., van Rosmalen, F., Sels, J.-W. E. M., Delnoij, T., Geyik, Z., Mingels, A. M. A., van Stipdonk, A. M. W., Prinzen, F. W., Ghossein-Doha, C., van Kuijk, S. M. J., van der Horst, I. C. C., Vernooy, K., & van Bussel, B. C. T. (2022). Serial Assessment of Myocardial Injury Markers in Mechanically Ventilated Patients With SARS-CoV-2 (from the Prospective MaastrICCht Cohort). American Journal of Cardiology, 170, 118-127. https://doi.org/10.1016/j.amjcard.2022.01.030
    • Alnima, T., Mulder, M. M. G., van Bussel, B. C. T., & Ten Cate, H. (2022). COVID-19 Coagulopathy: From Pathogenesis to Treatment. Acta Haematologica, 145(3), 282-296. https://doi.org/10.1159/000522498
    • Seelig, J., Trinks-Roerdink, E. M., Chu, G., Pisters, R., Theunissen, L., Trines, S. A., Pos, L., Kirchhof, C., de Jong, S., den Hartog, F. R., van Alem, A. P., Polak, P. E., Tieleman, R. G., van der Voort, P. H., Lenderink, T., Otten, A. M., de Jong, J., Gu, Y. L., Luermans, J., ... Hemels, M. (2022). Determinants of label non-adherence to non-vitamin K oral anticoagulants in patients with newly diagnosed atrial fibrillation. European heart journal open, 2(3), oeac022. Article oeac022. https://doi.org/10.1093/ehjopen/oeac022
    • Veninga, A., Baaten, C. C. F. M. J., De Simone, I., Tullemans, B. M. E., Kuijpers, M. J. E., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2022). Effects of Platelet Agonists and Priming on the Formation of Platelet Populations. Thrombosis and Haemostasis, 122(05), 726-738. https://doi.org/10.1055/s-0041-1735972
    • Koenen, M. T., Brandt, E. F., Kaczor, D. M., Caspers, T., Heinzmann, A. C. A., Fischer, P., Heinrichs, D., Wirtz, T. H., Trautwein, C., Koenen, R. R., & Berres, M.-L. (2022). Extracellular Vesicles from Steatotic Hepatocytes Provoke Pro-Fibrotic Responses in Cultured Stellate Cells. Biomolecules, 12(5), Article 698. https://doi.org/10.3390/biom12050698
    • Buziau, A. M., Eussen, S. J. P. M., Kooi, M. E., van der Kallen, C. J. H., van Dongen, M. C. J. M., Schaper, N. C., Henry, R. M. A., Schram, M. T., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Bekers, O., Meex, S. J. R., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Fructose Intake From Fruit Juice and Sugar-Sweetened Beverages Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study. Diabetes Care, 45(5), 1116-1123. https://doi.org/10.2337/dc21-2123
    • Willers, A., Swol, J., von Kuijk, S. M. J., Buscher, H., McQuilten, Z., ten Cate, H., Rycus, P. T., McKellar, S., Lorusso, R., & Tonna, J. E. (2022). HEROES V-V-HEmorRhagic cOmplications in Veno-Venous Extracorporeal life Support-Development and internal validation of multivariable prediction model in adult patients. Artificial Organs, 46(5), 932-952. https://doi.org/10.1111/aor.14148
    • Brozat, J. F., Brandt, E. F., Stark, M., Fischer, P., Wirtz, T. H., Flaßhove, A., Rodenhausen, A. N., Vajen, T., Heinzmann, A. C. A., Schmitz, S. M.-T., Abu Jhaisha, S., Röth, A. A., Koenen, R. R., Sahin, H., Trautwein, C., & Berres, M.-L. (2022). JAM-A is a multifaceted regulator in hepatic fibrogenesis, supporting LSEC integrity and stellate cell quiescence. Liver International, 42(5), 1185-1203. https://doi.org/10.1111/liv.15187
    • Koenen, R. R., & Weber, C. (2022). Jam-A Unleashed Incites Thromboinflammatory Coronary Artery Disease. JACC: Basic to Translational Science, 7(5), 462-464. https://doi.org/10.1016/j.jacbts.2022.03.014
    • Peters, L. J. F., Baaten, C. C. F. M. J., Maas, S. L., Lu, C., Nagy, M., Jooss, N. J., Bidzhekov, K., Santovito, D., Moreno-Andrés, D., Jankowski, J., Biessen, E. A. L., Döring, Y., Heemskerk, J. W. M., Weber, C., Kuijpers, M. J. E., & van der Vorst, E. P. C. (2022). MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice. Biomedicines, 10(5), Article 983. https://doi.org/10.3390/biomedicines10050983
    • Seelig, J., Chu, G., Trinks-Roerdink, E. M., Pisters, R., de Vries, T. A. C., Ten Cate, H., Geersing, G.-J., Rutten, F. H., Huisman, M. V., & Hemels, M. E. W. (2022). Unequal prescription of anticoagulants among females and males with atrial fibrillation and similar stroke risk: Should we omit sex category from the CHA2DS2-VASc score?Heart Rhythm, 19(5), 860-861. https://doi.org/10.1016/j.hrthm.2022.01.014
    • Limperger, V., Torge, A., Kiesau, B., Langer, F., Kenet, G., Mesters, R., Juhl, D., Stoll, M., Shneyder, M., Kowalski, D., Bajorat, T., Rocke, A., Kuta, P., Lasarow, L., Spengler, D., Junker, R., & Nowak-Göttl, U. (2022). Validation of a predictive model for identifying an increased risk for recurrence in adolescents and young adults with a first provoked thromboembolism. Blood Cells Molecules and Diseases, 94, Article 102651. https://doi.org/10.1016/j.bcmd.2022.102651
    • van Herpt, T. T. W., Timmermans, S. A. M. E. G., van Mook, W. N. K. A., van Bussel, B. C. T., van der Horst, I. C. C., Maessen, J. G., Natour, E., van Paassen, P., & Heuts, S. (2022). Postsurgical Thrombotic Microangiopathy and Deregulated Complement. Journal of Clinical Medicine, 11(9), Article 2501. https://doi.org/10.3390/jcm11092501
    • Leberzammer, J., Agten, S. M., Blanchet, X., Duan, R., Ippel, H., Megens, R. T. A., Schulz, C., Aslani, M., Duchene, J., Döring, Y., Jooss, N. J., Zhang, P., Brandl, R., Stark, K., Siess, W., Jurk, K., Heemskerk, J. W. M., Hackeng, T. M., Mayo, K. H., ... von Hundelshausen, P. (2022). Targeting platelet-derived CXCL12 impedes arterial thrombosis. Blood, 139(17), 2691-2705. https://doi.org/10.1182/blood.2020010140
    • Stultiens, J. M. G., Top, W. M. C., Kimenai, D. M., Lehert, P., Bekers, O., Stehouwer, C. D. A., Kooy, A., & Meex, S. J. R. (2022). Metformin and high-sensitivity cardiac troponin I and T trajectories in type 2 diabetes patients: a post-hoc analysis of a randomized controlled trial. Cardiovascular Diabetology, 21(1), Article 49. https://doi.org/10.1186/s12933-022-01482-z
    • Witten, A., Martens, L., Schäfer, A.-C., Troidl, C., Pankuweit, S., Vlacil, A.-K., Oberoi, R., Schieffer, B., Grote, K., Stoll, M., & Markus, B. (2022). Monocyte subpopulation profiling indicates CDK6-derived cell differentiation and identifies subpopulation-specific miRNA expression sets in acute and stable coronary artery disease. Scientific Reports, 12(1), Article 5589. https://doi.org/10.1038/s41598-022-08600-7
    • Denessen, E. J. S., Van den Kerkhof, D. L., Jeurissen, M. L. J., Wetzels, R. J. H., Verhezen, P. W. M., & Henskens, Y. M. C. (2022). Determining the Optimal Storage Time and Temperature for Performing Platelet Function Assays and Global Hemostasis Assays. Platelets, 33(3), 416-424. https://doi.org/10.1080/09537104.2021.1934666
    • Karel, M. F. A., Tullemans, B. M. E., D'Italia, G., Lemmens, T. P., Claushuis, T. A. M., Kuijpers, M. J. E., & Cosemans, J. M. E. M. (2022). Corrigendum to "The effect of Bruton's tyrosine kinase inhibitor ibrutinib on atherothrombus formation under stenotic flow conditions" [Thromb. Res. 212 (2022) 72-80]. Thrombosis Research, 213, 113-113. https://doi.org/10.1016/j.thromres.2022.03.012
    • Mesotten, D., Meijs, D. A. M., van Bussel, B. C. T., Stessel, B., Mehagnoul-Schipper, J., Hana, A., Scheeren, C. I. E., Strauch, U., van de Poll, M. C. G., Ghossein-Doha, C., Buhre, W. F. F. A., Bickenbach, J., Vander Laenen, M., Marx, G., van der Horst, I. C. C., & COVID Data Platform (CoDaP) Investigators (2022). Differences and Similarities Among COVID-19 Patients Treated in Seven ICUs in Three Countries Within One Region: An Observational Cohort Study. Critical Care Medicine, 50(4), 595-606. https://doi.org/10.1097/CCM.0000000000005314
    • Karel, M. F. A., Tullemans, B. M. E., D'Italia, G., Lemmens, T. P., Claushuis, T. A. M., Kuijpers, M. J. E., & Cosemans, J. M. E. M. (2022). The effect of Bruton's tyrosine kinase inhibitor ibrutinib on atherothrombus formation under stenotic flow conditions. Thrombosis Research, 212, 72-80. https://doi.org/10.1016/j.thromres.2022.02.020
    • Dolleman, S. C., Agten, S. M., Spronk, H. M. H., Hackeng, T. M., Bos, M. H. A., Versteeg, H. H., van Zonneveld, A. J., & de Boer, H. C. (2022). Thrombin in complex with dabigatran can still interact with PAR-1 via exosite-I and instigate loss of vascular integrity. Journal of Thrombosis and Haemostasis, 20(4), 996-1007. https://doi.org/10.1111/jth.15642
    • Alaour, B., Omland, T., Torsvik, J., Kaier, T. E., Sylte, M. S., Strand, H., Quraishi, J., McGrath, S., Williams, L., Meex, S., Redwood, S., Marber, M., & Aakre, K. M. (2022). Biological variation of cardiac myosin-binding protein C in healthy individuals. Clinical Chemistry and Laboratory Medicine, 60(4), 576-583. https://doi.org/10.1515/cclm-2021-0306
    • Neradova, A., Wasilewski, G., Prisco, S., Leenders, P., Caron, M., Welting, T., van Rietbergen, B., Kramann, R., Floege, J., Vervloet, M. G., & Schurgers, L. J. (2022). Combining phosphate binder therapy with vitamin K2 inhibits vascular calcification in an experimental animal model of kidney failure. Nephrology Dialysis Transplantation, 37(4), 652-662. https://doi.org/10.1093/ndt/gfab314
    • Linschoten, M., Uijl, A., Schut, A., Jakob, C. E. M., Romao, L. R., Bell, R. M., McFarlane, E., Stecher, M., Zondag, A. G. M., van Iperen, E. P. A., Hermans-van Ast, J. F., Lea, N. C., Schaap, J., Jewbali, L. S., Smits, P. C., Patel, R. S., Aujayeb, A., van Smeden, M., Siebelink, H. J., ... Raafs, A. (2022). Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries. European Heart Journal, 43(11), 1104-1120. https://doi.org/10.1093/eurheartj/ehab656
    • Hafeez, S., Ooi, H. W., Suylen, D., Duimel, H., Hackeng, T. M., van Blitterswijk, C., & Baker, M. B. (2022). Desymmetrization via Activated Esters Enables Rapid Synthesis of Multifunctional Benzene-1,3,5-tricarboxamides and Creation of Supramolecular Hydrogelators. Journal of the American Chemical Society, 144(9), 4057-4070. https://doi.org/10.1021/jacs.1c12685
    • Henkens, M. T. H. M., Raafs, A. G., Verdonschot, J. A. J., Linschoten, M., van Smeden, M., Wang, P., van der Hooft, B. H. M., Tieleman, R., Janssen, M. L. F., Ter Bekke, R. M. A., Hazebroek, M. R., van der Horst, I. C. C., Asselbergs, F. W., Magdelijns, F. J. H., Heymans, S. R. B., & CAPACITY-COVID collaborative consortium (2022). Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study. BMC Geriatrics, 22(1), Article 184. https://doi.org/10.1186/s12877-021-02673-1
    • Poelman, H., Ippel, H., Gurkan, B., Boelens, R., Vriend, G., van 't Veer, C., Lutgens, E., & Nicolaes, G. A. F. (2022). Structural anomalies in a published NMR-derived structure of IRAK-M. Journal of Molecular Graphics & Modelling, 111, Article 108061. https://doi.org/10.1016/j.jmgm.2021.108061
    • Dauwerse, S., ten Cate, H., Spronk, H. M. H., & Nagy, M. (2022). The Composition and Physical Properties of Clots in COVID-19 Pathology. Diagnostics, 12(3), Article 580. https://doi.org/10.3390/diagnostics12030580
    • Herrera-Rivero, M., Gandhi, S., Witten, A., Ghalawinji, A., Schotten, U., & Stoll, M. (2022). Cardiac chamber-specific genetic alterations suggest candidate genes and pathways implicating the left ventricle in the pathogenesis of atrial fibrillation. Genomics, 114(2), Article 110320. https://doi.org/10.1016/j.ygeno.2022.110320
    • Camaro, C., Bonnes, J. L., Adang, E. M., Spoormans, E. M., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J., van der Harst, P., van der Horst, I. C., Voskuil, M., ... van Royen, N. (2022). Cost Analysis From a Randomized Comparison of Immediate Versus Delayed Angiography After Cardiac Arrest. Journal of the American Heart Association, 11(5), Article e022238. https://doi.org/10.1161/JAHA.121.022238
    • Grover, S. P., Coughlin, T., Fleifil, S. M., Posma, J. J. N., Spronk, H. H. M., Heitmeier, S., Owens, A. P., & Mackman, N. (2022). Effect of combining aspirin and rivaroxaban on atherosclerosis in mice. Atherosclerosis, 345, 7-14. https://doi.org/10.1016/j.atherosclerosis.2022.02.010
    • Simons, C. C. J. M., Offermans, N. S. M., Stoll, M., van den Brandt, P. A., & Weijenberg, M. P. (2022). Empirical Investigation of Genomic Clusters Associated with Height and the Risk of Postmenopausal Breast and Colorectal Cancer in the Netherlands Cohort Study. American Journal of Epidemiology, 191(3), 413-429. https://doi.org/10.1093/aje/kwab259
    • Heubel-Moenen, F. C. J. I., Brouns, S. L. N., Herfs, L., Boerenkamp, L. S., Jooss, N. J., Wetzels, R. J. H., Verhezen, P. W. M., Machiels, P., Megy, K., Downes, K., Heemskerk, J. W. M., Beckers, E. A. M., & Henskens, Y. M. C. (2022). Multiparameter platelet function analysis of bleeding patients with a prolonged platelet function analyser closure time. British Journal of Haematology, 196(6), 1388-1400. https://doi.org/10.1111/bjh.18003
    • Panova-Noeva, M., Wagner, B., Nagler, M., Koeck, T., Ten Cate, V., Eggebrecht, L., Prochaska, J. H., Meyer, I., Gerdes, C., Spronk, H. M., Lackner, K. J., Ten Cate, H., Leineweber, K., Heitmeier, S., Konstantinides, S., & Wild, P. S. (2022). Variation of platelet function in clinical phenotypes of acute venous thromboembolism - Results from the GMP-VTE project. Journal of Thrombosis and Haemostasis, 20(3), 705-715. https://doi.org/10.1111/jth.15595
    • Post, D. S., van der Veer, A., Schijns, O. E. M. G., Klinkenberg, S., Rijkers, K., Wagner, G. L., van Kranen-Mastenbroek, V. H. J. M., Willems, P. C. P. H., Verhezen, P. W. M., Beckers, E. A. M., Heubel-Moenen, F. C. J. I., & Henskens, Y. M. C. (2022). Assessment of need for hemostatic evaluation in patients taking valproic acid: A retrospective cross-sectional study. PLOS ONE, 17(2), Article e0264351. https://doi.org/10.1371/journal.pone.0264351
    • Hegenbarth, J.-C., Lezzoche, G., De Windt, L. J., & Stoll, M. (2022). Perspectives on Bulk-Tissue RNA Sequencing and Single-Cell RNA Sequencing for Cardiac Transcriptomics. Frontiers in Molecular Medicine, 2, Article 839338. https://doi.org/10.3389/fmmed.2022.839338
    • Hrdinova, J., Fernández, D. I., Ercig, B., Tullemans, B. M. E., Suylen, D. P. L., Agten, S. M., Jurk, K., Hackeng, T. M., Vanhoorelbeke, K., Voorberg, J., Reutelingsperger, C. P. M., Wichapong, K., Heemskerk, J. W. M., & Nicolaes, G. A. F. (2022). Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear. International journal of molecular sciences, 23(4), Article 2046. https://doi.org/10.3390/ijms23042046
    • Cosemans, J. M. E. M. (2022). Platelet-derived MMP-2 in the prevention of plaque formation: how many strokes is par?European Heart Journal, 43(6), 515–517. https://doi.org/10.1093/eurheartj/ehab665
    • De With, R. R., Artola Arita, V., Nguyen, B.-O., Linz, D., Ten Cate, H., Spronk, H., Schotten, U., van Zonneveld, A. J., Erküner, Ö., Bayón, M. A., Schmidt, A. S., Luermans, J. G. L. M., Crijns, H. J. G. M., Van Gelder, I. C., & Rienstra, M. (2022). Different circulating biomarkers in women and men with paroxysmal atrial fibrillation: results from the AF-RISK and RACE V studies. EP Europace, 24(2), 193-201. https://doi.org/10.1093/europace/euab179
    • Spoormans, E. M., Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J. W., Girbes, A. R. J., van der Harst, P., van der Horst, I. C. C., Voskuil, M., van der Heijden, J. J., ... Elbers, P. W. G. (2022). Targeted Temperature Management in Out-of-Hospital Cardiac Arrest With Shockable Rhythm: A Post Hoc Analysis of the Coronary Angiography After Cardiac Arrest Trial. Critical Care Medicine, 50(2), e129-e142. https://doi.org/10.1097/CCM.0000000000005271
    • Karel, M. F. A., Lemmens, T. P., Tullemans, B. M. E., Wielders, S. J. H., Gubbins, E., van Beurden, D., van Rijt, S., & Cosemans, J. M. E. M. (2022). Characterization of Atherosclerotic Plaque Coating for Thrombosis Microfluidics Assays. Cellular and Molecular Bioengineering, 15(1), 55-65. https://doi.org/10.1007/s12195-021-00713-9
    • Grabowski, K., Herlan, L., Witten, A., Qadri, F., Eisenreich, A., Lindner, D., Schadlich, M., Schulz, A., Subrova, J., Mhatre, K. N., Primessnig, U., Plehm, R., van Linthout, S., Escher, F., Bader, M., Stoll, M., Westermann, D., Heinzel, F. R., & Kreutz, R. (2022). Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension. Hypertension Research, 45(2), 292-307. https://doi.org/10.1038/s41440-021-00826-8
    • Maag, A., van Rein, N., Schuijt, T. J., Kopatz, W. F., Kruijswijk, D., Thomassen, S., Hackeng, T. M., Camire, R. M., van der Poll, T., Meijers, J. C. M., Bos, M. H. A., & van't Veer, C. (2022). Major bleeding during oral anticoagulant therapy associated with factor V activation by factor Xa. Journal of Thrombosis and Haemostasis, 20(2), 328-338. https://doi.org/10.1111/jth.15589
    • Brouns, S. L. N., Tullemans, B. M. E., Bulato, C., Perrella, G., Campello, E., Spiezia, L., van Geffen, J. P., Kuijpers, M. J. E., van Oerle, R., Spronk, H. M. H., van der Meijden, P. E. J., Simioni, P., & Heemskerk, J. W. M. (2022). Protein C or Protein S deficiency associates with paradoxically impaired platelet-dependent thrombus and fibrin formation under flow. Research and practice in thrombosis and haemostasis, 6(2), Article e12678. https://doi.org/10.1002/rth2.12678
    • Boswijk, E., de Ligt, M., Habets, M. F. J., Mingels, A. M. A., van Marken Lichtenbelt, W. D., Mottaghy, F. M., Schrauwen, P., Wildberger, J. E., & Bucerius, J. (2022). Resveratrol treatment does not reduce arterial inflammation in males at risk of type 2 diabetes: a randomized crossover trial. Nuklearmedizin, 61(01), 33-41. https://doi.org/10.1055/a-1585-7215
    • Fernandez, D. I., Provenzale, I., Cheung, H. Y. F., van Groningen, J., Tullemans, B. M. E., Veninga, A., Dunster, J. L., Honarnejad, S., van den Hurk, H., Kuijpers, M. J. E., & Heemskerk, J. W. M. (2022). Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation. iScience, 25(1), Article 103718. https://doi.org/10.1016/j.isci.2021.103718
    • Spaetgens, B., Nagy, M., & ten Cate, H. (2022). Antiplatelet Therapy in Patients With COVID-19-More Is Less?JAMA-Journal of the American Medical Association, 327(3), 223-224. https://doi.org/10.1001/jama.2021.23866