Denisov, S. S., & Dijkgraaf, I. (2021). Immunomodulatory Proteins in Tick Saliva From a Structural Perspective. Frontiers in Cellular and Infection Microbiology, 11, Article 769574. https://doi.org/10.3389/fcimb.2021.769574

Klinkhammer, S., Horn, J., Visser-Meilij, J. M. A., Verwijk, E., Duits, A., Slooter, A. J. C., van Heugten, C. M., NeNeSCo study group, Aries, M., van Bussel, B., Janssen, M., Postma - Jacobi, L., & van Santen, S. (2021). Dutch multicentre, prospective follow-up, cohort study comparing the neurological and neuropsychological sequelae of hospitalised non-ICU- and ICU-treated COVID-19 survivors: a study protocol. BMJ Open, 11(10), Article e054901. https://doi.org/10.1136/bmjopen-2021-054901

Fernandez, D. I., Kuijpers, M. J. E., & Heemskerk, J. W. M. (2021). Platelet calcium signaling by G-protein coupled and ITAM-linked receptors regulating anoctamin-6 and procoagulant activity. Platelets, 32(7), 863-871. https://doi.org/10.1080/09537104.2020.1859103

Ho, L. T. S., McVey, M. J., Kuiper, G. J. A. J. M., Gross, P. L., & Karkouti, K. (2021). Analysis of the effect of varying protamine-to-heparin ratio on coagulation in vitro. British Journal of Anaesthesia, 127(4), E128-E130. https://doi.org/10.1016/j.bja.2021.06.037

Todaro, A. M., Hackeng, T. M., & Castoldi, E. (2021). Antisense-Mediated Down-Regulation of Factor V-Short Splicing in a Liver Cell Line Model. Applied Sciences, 11(20), Article 9621. https://doi.org/10.3390/app11209621

Ercig, B., Arfman, T., Hrdinova, J., Wichapong, K., Reutelingsperger, C. P. M., Vanhoorelbeke, K., Nicolaes, G. A. F., & Voorberg, J. (2021). Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity. Journal of Biological Chemistry, 297(4), Article 101132. https://doi.org/10.1016/j.jbc.2021.101132

van Gassel, R. J. J., Bels, J., Remij, L., van Bussel, B. C. T., Posthuma, R., Gietema, H. A., Verbunt, J., van der Horst, I. C. C., Damink, S. W. M. O., van Santen, S., & van de Poll, M. C. G. (2021). Functional Outcomes and Their Association With Physical Performance in Mechanically Ventilated Coronavirus Disease 2019 Survivors at 3 Months Following Hospital Discharge: A Cohort Study. Critical Care Medicine, 49(10), 1726-1738. https://doi.org/10.1097/CCM.0000000000005089

Gijs, M., Veugen, J. M. J., Wolffs, P. F. G., Savelkoul, P. H. M., Tas, J., van Bussel, B. C. T., de Kruif, M. D., Henry, R. M. A., Webers, C. A. B., Dickman, M. M., & Nuijts, R. M. M. A. (2021). In-Depth Investigation of Conjunctival Swabs and Tear Fluid of Symptomatic COVID-19 Patients, an Observational Cohort Study. Translational Vision Science & Technology, 10(12), Article 32. https://doi.org/10.1167/tvst.10.12.32

Tullemans, B. M. E., Veninga, A., Fernandez, D. I., Aarts, M. J. B., Eble, J. A., van der Meijden, P. E. J., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2021). Multiparameter Evaluation of the Platelet-Inhibitory Effects of Tyrosine Kinase Inhibitors Used for Cancer Treatment. International Journal of Molecular Sciences, 22(20), Article 11199. https://doi.org/10.3390/ijms222011199

Kimenai, D. M., Shah, A. S. V., McAllister, D. A., Lee, K. K., Tsanas, A., Meex, S. J. R., Porteous, D. J., Hayward, C., Campbell, A., Sattar, N., Mills, N. L., & Welsh, P. (2021). Sex Differences in Cardiac Troponin I and T and the Prediction of Cardiovascular Events in the General Population. Clinical Chemistry, 67(10), 1351-1360. https://doi.org/10.1093/clinchem/hvab109

Jiritano, F., Fina, D., Lorusso, R., ten Cate, H., Kowalewski, M., Matteucci, M., Serra, R., Mastroroberto, P., & Serraino, G. F. (2021). Systematic review and meta-analysis of the clinical effectiveness of point-of-care testing for anticoagulation management during ECMO. Journal of Clinical Anesthesia, 73, Article 110330. https://doi.org/10.1016/j.jclinane.2021.110330

Schreurs, R. H. P., Joore, M. A., ten Cate, H., & ten Cate-Hoek, A. J. (2021). Using the Functional Resonance Analysis Method to explore how elastic compression therapy is organised and could be improved from a multistakeholder perspective. BMJ Open, 11(10), Article e048331. https://doi.org/10.1136/bmjopen-2020-048331

Olie, R. H., van der Meijden, P. E. J., Vries, M. J. A., Veenstra, L., van't Hof, A. W. J., ten Berg, J. M., Henskens, Y. M. C., & ten Cate, H. (2021). Antithrombotic therapy in high-risk patients after percutaneous coronary intervention; study design, cohort profile and incidence of adverse events. Netherlands Heart Journal, 29(10), 525-535. https://doi.org/10.1007/s12471-021-01606-2

Heinzmann, A. C. A., Coenen, D. M., Vajen, T., Cosemans, J. M. E. M., & Koenen, R. R. (2021). Combined Antiplatelet Therapy Reduces the Proinflammatory Properties of Activated Platelets. TH open : companion journal to thrombosis and haemostasis, 5(4), e533-e542. https://doi.org/10.1055/a-1682-3415

Slikkerveer, M., van de Plas, A., Driessen, J. H. M., Wijngaard, R., de Vries, F., Olie, R., Meertens, N., & van den Bemt, P. (2021). Prescribing Errors With Low-Molecular-Weight Heparins. Journal of Patient Safety, 17(7), e587-e592. https://doi.org/10.1097/PTS.0000000000000417

Boekel, M. F., Venema, C. S., Kaufmann, T., van der Horst, I. C. C., Vos, J. J., & Scheeren, T. W. L. (2021). The effect of compliance with a perioperative goal-directed therapy protocol on outcomes after high-risk surgery: a before-after study. Journal of Clinical Monitoring and Computing, 35(5), 1193-1202. https://doi.org/10.1007/s10877-020-00585-w

Huckriede, J., de Vries, F., Hultstroem, M., Wichapong, K., Reutelingsperger, C., Lipcsey, M., de Frutos, P. G., Frithiof, R., & Nicolaes, G. A. F. (2021). Histone H3 Cleavage in Severe COVID-19 ICU Patients. Frontiers in Cellular and Infection Microbiology, 11, Article 694186. https://doi.org/10.3389/fcimb.2021.694186

De Majo, F., Martens, L., Hegenbarth, J. C., Ruhle, F., Hamczyk, M. R., Nevado, R. M., Andres, V., Hilbold, E., Bar, C., Thum, T., de Boer, M., Duncker, D. J., Schroen, B., Armand, A. S., Stoll, M., & De Windt, L. J. (2021). Genomic instability in the naturally and prematurely aged myocardium. Proceedings of the National Academy of Sciences of the United States of America, 118(36), Article e2022974118. https://doi.org/10.1073/pnas.2022974118

Linz, D., Verheule, S., Isaacs, A., & Schotten, U. (2021). Considerations for the Assessment of Substrates, Genetics and Risk Factors in Patients with Atrial Fibrillation. Arrhythmia & Electrophysiology Review, 10(3), 132-139. https://doi.org/10.15420/aer.2020.51

Olie, R. H., Hensgens, R. R. K., Wijnen, P. A. H. M., Veenstra, L. F., de Greef, B. T. A., Vries, M. J. A., van der Meijden, P. E. J., ten Berg, J. M., ten Cate, H., Bekers, O., & Henskens, Y. M. C. (2021). Differential Impact of Cytochrome 2C19 Allelic Variants on Three Different Platelet Function Tests in Clopidogrel-Treated Patients. Journal of Clinical Medicine, 10(17), Article 3992. https://doi.org/10.3390/jcm10173992

Kimenai, D. M., Lindahl, B., Chapman, A. R., Baron, T., Gard, A., Wereski, R., Meex, S. J. R., Jernberg, T., Mills, N. L., & Eggers, K. M. (2021). Sex differences in investigations and outcomes among patients with type 2 myocardial infarction. Heart, 107(18), 1480-1486. https://doi.org/10.1136/heartjnl-2021-319118

D'Ambrosi, S., Visser, A., Antunes-Ferreira, M., Poutsma, A., Giannoukakos, S., Sol, N., Sabrkhany, S., Bahce, I., Kuijpers, M. J. E., Egbrink, M. G. A. O., Griffioen, A. W., Best, M. G., Koppers-Lalic, D., Oudejans, C., & Wurdinger, T. (2021). The Analysis of Platelet-Derived circRNA Repertoire as Potential Diagnostic Biomarker for Non-Small Cell Lung Cancer. Cancers, 13(18), Article 4644. https://doi.org/10.3390/cancers13184644

Heuts, S., Ubben, J. F., Banks-Gonzales, V., Sels, J.-W., Lorusso, R., van Mook, W. N. K. A., & Delnoij, T. S. R. (2021). Nitric Oxide Ventilation Improves Recirculation and Right Ventricular Function During Veno-Venous Extracorporeal Membrane Oxygenation in a COVID-19 Patient. Journal of Cardiothoracic and Vascular Anesthesia, 35(9), 2763-2767. https://doi.org/10.1053/j.jvca.2020.09.137

Herrera-Rivero, M., Stoll, M., Hegenbarth, J. C., Ruhle, F., Limperger, V., Junker, R., Franke, A., Hoffmann, P., Shneyder, M., Stach, M., & Nowak-Gottl, U. (2021). Single- and Multimarker Genome-Wide Scans Evidence Novel Genetic Risk Modifiers for Venous Thromboembolism. Thrombosis and Haemostasis, 121(09), 1169-1180. https://doi.org/10.1055/s-0041-1723988

van Gorp, R. H., Baaten, C. C. F. M. J., Habibi, A., Jaminon, A. M. G., Peeters, F. E. C. M., Leenders, P., Crijns, H. J. G. M. C., Heemskerk, J. W. M., Reutelingsperger, C. P., Spronk, H. M., & Schurgers, L. J. (2021). Vitamin K antagonist use induces calcification and atherosclerotic plaque progression resulting in increased hypercoagulability. European heart journal open, 1(2), Article oeab017. https://doi.org/10.1093/ehjopen/oeab017

Giesen, P. L. A., Gulpen, A. J. W., van Oerle, R., ten Cate, H., Nagy, M., & Spronk, H. M. H. (2021). Calibrated automated thrombogram II: removing barriers for thrombin generation measurements. Thrombosis Journal, 19(1), Article 60. https://doi.org/10.1186/s12959-021-00312-8

ten Cate, H. (2021). Surviving Covid-19 with Heparin?New England Journal of Medicine, 385(9), 845-846. https://doi.org/10.1056/NEJMe2111151

Huckriede, J., Anderberg, S. B., Morales, A., de Vries, F., Hultstrom, M., Bergqvist, A., Ortiz-Perez, J. T., Sels, J. W., Wichapong, K., Lipcsey, M., van de Poll, M., Larsson, A., Luther, T., Reutelingsperger, C., Garcia de Frutos, P., Frithiof, R., & Nicolaes, G. A. F. (2021). Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients. Scientific Reports, 11(1), Article 15701. https://doi.org/10.1038/s41598-021-95209-x

Hulshof, A. M., Braeken, D. C. W., Ghossein-Doha, C., van Santen, S., Sels, J. W. E. M., Kuiper, G. J. A. J. M., van der Horst, I. C. C., ten Cate, H., van Bussel, B. C. T., Olie, R. H., & Henskens, Y. M. C. (2021). Hemostasis and fibrinolysis in COVID-19 survivors 6 months after intensive care unit discharge. Research and practice in thrombosis and haemostasis, 5(6), Article e12579. https://doi.org/10.1002/rth2.12579

Coenen, D. M., Heinzmann, A. C. A., Oggero, S., Albers, H. J., Nagy, M., Hague, P., Kuijpers, M. J. E., Vanderwinden, J. M., van der Meer, A. D., Perretti, M., Koenen, R. R., & Cosemans, J. M. E. M. (2021). Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions. Cells, 10(8), Article 1998. https://doi.org/10.3390/cells10081998

Willers, A., Arens, J., Mariani, S., Pels, H., Maessen, J. G., Hackeng, T. M., Lorusso, R., & Swol, J. (2021). New Trends, Advantages and Disadvantages in Anticoagulation and Coating Methods Used in Extracorporeal Life Support Devices. Membranes, 11(8), Article 617. https://doi.org/10.3390/membranes11080617

Ten Cate, H., Guzik, T. J., Eikelboom, J., & Spronk, H. M. H. (2021). Pleiotropic actions of factor Xa inhibition in cardiovascular prevention - mechanistic insights and implications for anti-thrombotic treatment. Cardiovascular Research, 117(9), 2030-2044. https://doi.org/10.1093/cvr/cvaa263

ten Cate, H., & Lammle, B. (2021). Special Issue: "The Latest Clinical Advances in Thrombocytopenia". Journal of Clinical Medicine, 10(16), Article 3463. https://doi.org/10.3390/jcm10163463

Aarsetøy, R., Ten Cate, H., Spronk, H., Van Oerle, R., Aarsetøy, H., Staines, H., & Nilsen, D. W. T. (2021). Activated factor XI-antithrombin complex presenting as an independent predictor of 30-days mortality in out-of-hospital cardiac arrest patients. Thrombosis Research, 204, 1-8. https://doi.org/10.1016/j.thromres.2021.05.014

Livneh, N., Braeken, D., Drozdinsky, G., Gafter-Gvili, A., Seelig, J., Rozovski, U., Berger, T., Raanani, P., Falanga, A., ten Cate, H., Spectre, G., & Leader, A. (2021). Anticoagulation in patients with atrial fibrillation, thrombocytopenia and hematological malignancy. Journal of Thrombosis and Thrombolysis, 52(2), 590-596. https://doi.org/10.1007/s11239-021-02393-8

Beldhuis, I. E., Marapin, R. S., Jiang, Y. Y., de Souza, N. F. S., Georgiou, A., Kaufmann, T., Forte, J. C., & van der Horst, I. C. C. (2021). Cognitive biases, environmental, patient and personal factors associated with critical care decision making: A scoping review. Journal of Critical Care, 64, 144-153. https://doi.org/10.1016/j.jcrc.2021.04.012

Kurniawati, E. R., Rutjens, V. G. H., Vranken, N. P. A., Delnoij, T. S. R., Lorusso, R., van der Horst, I. C. C., Maessen, J. G., & Weerwind, P. W. (2021). Quality of life following adult veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review. Quality of Life Research, 30(8), 2123-2135. https://doi.org/10.1007/s11136-021-02834-0

Dahlen, B., Schulz, A., Göbel, S., Tröbs, S.-O., Schwuchow-Thonke, S., Spronk, H. M., Prochaska, J. H., Arnold, N., Lackner, K. J., Gori, T., Ten Cate, H., Münzel, T., Wild, P. S., & Panova-Noeva, M. (2021). The impact of platelet indices on clinical outcome in heart failure: results from the MyoVasc study. Esc heart failure, 8(4), 2991-3001. https://doi.org/10.1002/ehf2.13390

Forte, C., Voinea, A., Chichirau, M., Yeshmagambetova, G., Albrecht, L. M., Erfurt, C., Freundt, L. A., Carmo, L. O. E., Henning, R. H., van der Horst, I. C. C., Sundelin, T., Wiering, M. A., Axelsson, J., & Epema, A. H. (2021). Deep Learning for Identification of Acute Illness and Facial Cues of Illness. Frontiers in medicine, 8, Article 661309. https://doi.org/10.3389/fmed.2021.661309

Vroomen, M., van Rosmalen, F., Schroeder, J., Philippens, S., Delhaas, T., Crijns, H. J., & Pison, L. (2021). Ten-year follow-up after endocardial point-by-point cryoablation for paroxysmal atrial fibrillation. Acta Cardiologica, 76(4), 425-430. https://doi.org/10.1080/00015385.2020.1756087

Barbateskovic, M., Koster, T. M., Eck, R. J., Maagaard, M., Afshari, A., Blokzijl, F., Cronhjort, M., Dieperink, W., Fabritius, M. L., Feinberg, J., French, C., Gareb, B., Geisler, A., Granholm, A., Hiemstra, B., Hu, R. X., Imberger, G., Jensen, B. T., Jonsson, A. B., ... Wetterslev, J. (2021). A new tool to assess Clinical Diversity In Meta-analyses (CDIM) of interventions. Journal of Clinical Epidemiology, 135, 29-41. https://doi.org/10.1016/j.jclinepi.2021.01.023

Bavalia, R., Bistervels, I. M., Boersma, W. G., Quere, I., Brisot, D., Falvo, N., Stephan, D., Couturaud, F., Schellong, S., Montaclair, K., Ghanima, W., ten Wolde, M., Coppens, M., Ferrari, E., Sanchez, O., Carroll, P., Kahn, S. R., Meijer, K., Birocchi, S., ... Hokusai Post-PE Study Investigator (2021). Quality of life in patients with pulmonary embolism treated with edoxaban versus warfarin. Research and practice in thrombosis and haemostasis, 5(5), Article e12566. https://doi.org/10.1002/rth2.12566

Driessen, R. G. H., Kiers, D., Schalkwijk, C. G., Scheijen, J. L. J. M., Gerretsen, J., Pickkers, P., van de Poll, M. C. G., van der Horst, I. C. C., Bergmans, D. C. J. J., Kox, M., & van Bussel, B. C. T. (2021). Systemic inflammation down-regulates glyoxalase-1 expression: an experimental study in healthy males. Bioscience Reports, 41(7), Article BSR20210954. https://doi.org/10.1042/BSR20210954

Lemkes, J. S., Spoormans, E. M., Demirkiran, A., Leutscher, S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J. W., van der Harst, P., van der Horst, I. C. C., Voskuil, M., ... van Royen, N. (2021). The effect of immediate coronary angiography after cardiac arrest without ST-segment elevation on left ventricular function. A sub-study of the COACT randomised trial. Resuscitation, 164, 93-100. https://doi.org/10.1016/j.resuscitation.2021.04.020

Camps, E. C., van Lith, S. A. M., Frielink, C., Lankhof, J., Dijkgraaf, I., Gotthardt, M., & Brock, R. (2021). CPPs to the Test: Effects on Binding, Uptake and Biodistribution of a Tumor Targeting Nanobody. Pharmaceuticals, 14(7), Article 602. https://doi.org/10.3390/ph14070602

Petersohn, S., Grimm, S. E., Ramaekers, B. L. T., ten Cate-Hoek, A. J., & Joore, M. A. (2021). Exploring the Feasibility of Comprehensive Uncertainty Assessment in Health Economic Modeling: A Case Study. Value in Health, 24(7), 983-994. https://doi.org/10.1016/j.jval.2021.01.004

Castoldi, E. (2021). F5-Atlanta: Factor V-short strikes again. Journal of Thrombosis and Haemostasis, 19(7), 1638-1640. https://doi.org/10.1111/jth.15351

Denisov, S. S., Ippel, J. H., Castoldi, E., Mans, B. J., Hackeng, T. M., & Dijkgraaf, I. (2021). Molecular basis of anticoagulant and anticomplement activity of the tick salivary protein Salp14 and its homologs. Journal of Biological Chemistry, 297(1), Article 100865. https://doi.org/10.1016/j.jbc.2021.100865

Herfs, L., Swieringa, F., Jooss, N., Kozlowski, M., Heubel-Moenen, F. C. J., van Oerle, R., Machiels, P., Henskens, Y., & Heemskerk, J. W. M. (2021). Multiparameter microfluidics assay of thrombus formation reveals increased sensitivity to contraction and antiplatelet agents at physiological temperature. Thrombosis Research, 203, 46-56. https://doi.org/10.1016/j.thromres.2021.04.014

Liu, X., Arfman, T., Wichapong, K., Reutelingsperger, C. P. M., Voorberg, J., & Nicolaes, G. A. F. (2021). PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune-mediated disease. Journal of Thrombosis and Haemostasis, 19(7), 1607-1617. https://doi.org/10.1111/jth.15313