Publications
- 2024
- Harlacher, E., Schulte, C., Vondenhoff, S., Schmitt-Kopplin, P., Diederich, P., Hemmers, C., Moellmann, J., Wollenhaupt, J., Veltrop, R., Biessen, E., Lehrke, M., Peters, B., Schlieper, G., Kuppe, C., Floege, J., Jankowski, V., Marx, N., Jankowski, J., & Noels, H. (2024). Increased levels of a mycophenolic acid metabolite in patients with kidney failure negatively affect cardiomyocyte health. Frontiers in Cardiovascular Medicine, 11, Article 1346475. https://doi.org/10.3389/fcvm.2024.1346475
- Vos, W. G., van Os, B. W., den Toom, M., Beckers, L., van Roomen, C. P. A. A., van Tiel, C. M., Mohapatra, B. C., Band, H., Nitz, K., Weber, C., Atzler, D., de Winther, M. P. J., Bosmans, L. A., Lutgens, E., & Seijkens, T. T. P. (2024). T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation. Frontiers in Immunology, 15, Article 1297893. https://doi.org/10.3389/fimmu.2024.1297893
- Aakre, K. M., Apple, F. S., Mills, N. L., Meex, S. J. R., Collinson, P. O., & International Federation of Clinical Chemistry Committee on Clinical Applications of Cardiac Biomarkers (IFCC C-CB) (2024). Lower Limits for Reporting High-Sensitivity Cardiac Troponin Assays and Impact of Analytical Performance on Patient Misclassification. Clinical Chemistry, 70(3), 497-505. Article hvad185. https://doi.org/10.1093/clinchem/hvad185
- van Doorn, W. P. T. M., Helmich, F., van Dam, P. M. E. L., Jacobs, L. H. J., Stassen, P. M., Bekers, O., & Meex, S. J. R. (2024). Explainable Machine Learning Models for Rapid Risk Stratification in the Emergency Department: A Multicenter Study. Journal of Applied Laboratory Medicine, 9(2), 212-222. Article jfad094. https://doi.org/10.1093/jalm/jfad094
- Goedhart, T. M. H. J., Bukkems, L. H., Zwagemaker, A. F., Coppens, M., Fijnvandraat, K., Schols, S. E. M., Schutgens, R. E. G., Eikenboom, J., Heubel-Moenen, F. C. J. I., Ypma, P. F., Nieuwenhuizen, L., Meijer, K., Leebeek, F. W. G., Mathôt, R. A. A., Cnossen, M. H., & OPTI-CLOT study group and SYMPHONY consortium (2024). Predictive performance of pharmacokinetic-guided prophylactic dosing of factor concentrates in hemophilia A and B. Research and practice in thrombosis and haemostasis, 8(3), Article 102397. https://doi.org/10.1016/j.rpth.2024.102397
- Romano, L. G. R., Schütte, L. M., van Hest, R. M., Meijer, K., Laros-van Gorkom, B. A. P., Nieuwenhuizen, L., Eikenboom, J., Heubel-Moenen, F. C. J. I., Uitslager, N., Coppens, M., Fijnvandraat, K., Driessens, M. H. E., Polinder, S., Cnossen, M. H., Leebeek, F. W. G., Mathôt, R. A. A., Kruip, M. J. H. A., & DAVID and SYMPHONY Consortium (2024). Tachyphylaxis and reproducibility of desmopressin response in perioperative persons with nonsevere hemophilia A: implications for clinical practice. Research and practice in thrombosis and haemostasis, 8(3), Article 102367. https://doi.org/10.1016/j.rpth.2024.102367
- Vondenhoff, S., Schunk, S. J., & Noels, H. (2024). Erhöhtes kardiovaskuläres Risiko bei Patienten mit chronischer Niereninsuffizienz. Herz, 49(2), 95-104. https://doi.org/10.1007/s00059-024-05235-4
- Romano, L. G. R., Schutte, L. M., van Hest, R. M., Meijer, K., Laros-van Gorkom, B. A. P., Nieuwenhuizen, L., Eikenboom, J., Heubel-Moenen, F. C. J. I., Uitslager, N., Coppens, M., Fijnvandraat, K., Driessens, M. H. E., Polinder, S., Cnossen, M. H., Leebeek, F. W. G., Mathot, R. A. A., Kruip, M. J. H. A., & DAVID SYMPHONY Consortium (2024). Peri-operative desmopressin combined with pharmacokinetic-guided factor VIII concentrate in non-severe haemophilia A patients. Haemophilia, 30(2), 355-366. https://doi.org/10.1111/hae.14946
- Hegeman, R. R. M. J. J., van Ginkel, D.-J., Längle, S., Timmers, L., Rensing, B. J. W. M., de Kroon, T. L., Sonker, U., Kelder, J. C., Mach, M., Andreas, M., Swaans, M. J., Ten Berg, J. M., & Klein, P. (2024). Preoperative computed tomography-imaging with patient-specific computer simulation in transcatheter aortic valve implantation: Design and rationale of the GUIDE-TAVI trial. American heart journal, 269, 158-166. https://doi.org/10.1016/j.ahj.2023.12.017
- Provenzale, I., Solari, F. A., Schoenichen, C., Brouns, S. L. N., Fernandez, D. I., Kuijpers, M. J. E., van Der Meijden, P. E. J., Gibbins, J. M., Sickmann, A., Jones, C., & Heemskerk, J. W. M. (2024). Endothelium-mediated regulation of platelet activation: Involvement of multiple protein kinases. Faseb Journal, 38(4), Article e23468. https://doi.org/10.1096/fj.202300360RR
- Oomen, I., Verhagen, M., Miranda, M., Allacher, P., Beckers, E. A. M., Blijlevens, N. M. A., van der Bom, J. G., Coppens, M., Driessens, M., Eikenboom, J. C. J., Fijnvandraat, K., Hassan, S., van Heerde, W. L., Hooimeijer, H. L., Jansen, J. H., Kaijen, P., Leebeek, F. W. G., Meijer, D., Paul, H., ... Gouw, S. C. (2024). The spectrum of neutralizing and non-neutralizing anti-FVIII antibodies in a nationwide cohort of 788 persons with hemophilia A. Frontiers in Immunology, 15, Article 1355813. https://doi.org/10.3389/fimmu.2024.1355813
- ten Berg, J. M., Overduin, D. C., & van Ginkel, D. J. (2024). What Oral Anticoagulant Is Best After TAVR: Vitamin K Antagonists or Direct Oral Anticoagulants?Jacc-Cardiovascular Interventions, 17(3), 419-421. https://doi.org/10.1016/j.jcin.2023.12.024
- Hulshof, A. M., Nab, L., van Rosmalen, F., de Kok, J., Mulder, M. M. G., Hellenbrand, D., Sels, J. W. E. M., ten Cate, H., Cannegieter, S. C., Henskens, Y. M. C., & van Bussel, B. C. T. (2024). Rotational thromboelastometry as a biomarker for mortality — The Maastricht Intensive Care COVID cohort. Thrombosis Research, 234, 51-58. https://doi.org/10.1016/j.thromres.2023.12.010
- Iding, A. F. J., Limpens, T. M. P., Ten Cate, H., & Ten Cate-Hoek, A. J. (2024). Chronic inflammatory diseases increase the risk of post-thrombotic syndrome: A prospective cohort study. European journal of internal medicine, 120, 85-91. https://doi.org/10.1016/j.ejim.2023.10.014
- Döring, Y., van der Vorst, E. P. C., Yan, Y., Neideck, C., Blanchet, X., Jansen, Y., Kemmerich, M., Bayasgalan, S., Peters, L. J. F., Hristov, M., Bidzhekov, K., Yin, C., Zhang, X., Leberzammer, J., Li, Y., Park, I., Kral, M., Nitz, K., Parma, L., ... Weber, C. (2024). Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis. Nature cardiovascular research, 3(2), 221-242. https://doi.org/10.1038/s44161-023-00413-9
- Prandoni, P., Haas, S., Fluharty, M. E., Schellong, S., Gibbs, H., Tse, E., Carrier, M., Jacobson, B., ten Cate, H., Panchenko, E., Verhamme, P., Pieper, K., Kayani, G., Kakkar, L. A., & GARFIELD-VTE Investigators (2024). Incidence and predictors of post-thrombotic syndrome in patients with proximal DVT in a real-world setting: findings from the GARFIELD-VTE registry. Journal of Thrombosis and Thrombolysis, 57(2), 312-321. https://doi.org/10.1007/s11239-023-02895-7
- Todaro, A. M., Radu, C. M., Ciccone, M., Toffanin, S., Serino, M. L., Campello, E., Bulato, C., Lunghi, B., Gemmati, D., Cuneo, A., Hackeng, T. M., Simioni, P., Bernardi, F., & Castoldi, E. (2024). In vitro and ex vivo rescue of a nonsense mutation responsible for severe coagulation factor V deficiency. Journal of Thrombosis and Haemostasis, 22(2), 410-422. https://doi.org/10.1016/j.jtha.2023.10.007
- Reutelingsperger, C. P. M., Gijbels, M. J., Spronk, H., Van Oerle, R., Schrijver, R., Ekhart, P., de Kimpe, S., & Nicolaes, G. A. F. (2024). M6229 Protects against Extracellular-Histone-Induced Liver Injury, Kidney Dysfunction, and Mortality in a Rat Model of Acute Hyperinflammation. International Journal of Molecular Sciences, 25(3), Article 1376. https://doi.org/10.3390/ijms25031376
- Roos-Blom, M.-J., Bakhshi-Raiez, F., Brinkman, S., Arbous, M. S., van den Berg, R., Bosman, R. J., van Bussel, B. C. T., Erkamp, M. L., de Graaff, M. J., Hoogendoorn, M. E., de Lange, D. W., Moolenaar, D., Spijkstra, J. J., de Waal, R. A. L., Dongelmans, D. A., & de Keizer, N. F. (2024). Quality improvement of Dutch ICUs from 2009 to 2021: A registry based observational study. Journal of Critical Care, 79, Article 154461. https://doi.org/10.1016/j.jcrc.2023.154461
- Gimbel, M. E., Yin, D. R. P. P. C. P., van den Broek, W. W. A., Hermanides, R. S., Kauer, F., Tavenier, A. H., Schellings, D., Brinckman, S. L., The, S. H. K., Stoel, M. G., Heestermans, T. A. C. M., Rasoul, S., Emans, M. E., van de Wetering, M., van Bergen, P. F. M. M., Walhout, R., Nicastia, D., Aksoy, I., van 't Hof, A., ... ten Berg, J. M. (2024). Treatment of elderly patients with non-ST-elevation myocardial infarction: the nationwide POPular age registry. Netherlands Heart Journal, 32(2), 84-90. https://doi.org/10.1007/s12471-023-01812-0
- Arfman, T., Zollet, V., van Es, N., Bosch, F. T. M., Nicolaes, G. A. F., Sorvillo, N., & Voorberg, J. (2024). Elevated levels of citrullinated fibrinogen in patients with cancer. eJHaem, 5(1), 136-140. https://doi.org/10.1002/jha2.825
- van Dam, P. M. E. L., van Doorn, W. P. T. M., van Gils, F., Sevenich, L., Lambriks, L., Meex, S. J. R., Cals, J. W. L., & Stassen, P. M. (2024). Machine learning for risk stratification in the emergency department (MARS-ED) study protocol for a randomized controlled pilot trial on the implementation of a prediction model based on machine learning technology predicting 31-day mortality in the emergency department. Scandinavian Journal of Trauma Resuscitation & Emergency Medicine, 32(1), Article 5. https://doi.org/10.1186/s13049-024-01177-2
- Olie, R. H., Winckers, K., Rocca, B., & Ten Cate, H. (2024). Oral Anticoagulants Beyond Warfarin. Annual Review of Pharmacology and Toxicology, 64, 551-575. https://doi.org/10.1146/annurev-pharmtox-032823-122811
- Loots, F. J., van der Meulen, M. P., Smits, M., Hopstaken, R. M., de Bont, E. G., van Bussel, B. C., Latten, G. H., Oosterheert, J. J., van Zanten, A. R., Verheij, T. J., & Frederix, G. W. (2024). Potential impact of a new sepsis prediction model for the primary care setting: early health economic evaluation using an observational cohort. BMJ Open, 14(1), 071598. Article e071598. https://doi.org/10.1136/bmjopen-2023-071598
- Ten Berg, J. M., Overduin, D. C., & van Ginkel, D. J. (2024). Best Oral Anticoagulant for Transcatheter Mitral Valve Replacement. Journal of the American College of Cardiology, 83(2), 347-349. https://doi.org/10.1016/j.jacc.2023.11.005
- Termorshuizen, F., Dongelmans, D. A., Brinkman, S., Bakhshi-Raiez, F., Arbous, M. S., de Lange, D. W., van Bussel, B. C. T., & de Keizer, N. F. (2024). Characteristics and outcome of COVID-19 patients admitted to the ICU: a nationwide cohort study on the comparison between the consecutive stages of the COVID-19 pandemic in the Netherlands, an update. Annals of Intensive Care, 14(1), Article 11. https://doi.org/10.1186/s13613-023-01238-2
- Lip, G. Y. H., Rigby, A., & Weber, C. (2024). A Happy New Year 2024 from Thrombosis and Haemostasis!Thrombosis and Haemostasis, 124(1), 1-3. https://doi.org/10.1055/s-0043-1778033
- Weber, C., Rigby, A., & Lip, G. Y. H. (2024). Thrombosis and Haemostasis 2023 Editors' Choice Papers. Thrombosis and Haemostasis, 124(1), 80-87. https://doi.org/10.1055/s-0043-1778032
- de Kok, J. W. T. M., van Rosmalen, F., Koeze, J., Keus, F., van Kuijk, S. M. J., Castela Forte, J., Schnabel, R. M., Driessen, R. G. H., van Herpt, T. T. W., Sels, J.-W. E. M., Bergmans, D. C. J. J., Lexis, C. P. H., van Doorn, W. P. T. M., Meex, S. J. R., Xu, M., Borrat, X., Cavill, R., van der Horst, I. C. C., & van Bussel, B. C. T. (2024). Deep embedded clustering generalisability and adaptation for integrating mixed datatypes: two critical care cohorts. Scientific Reports, 14(1), Article 1045. https://doi.org/10.1038/s41598-024-51699-z
- Guerkan, B., Poelman, H., Pereverzeva, L., Kruijswijk, D., de Vos, A. F., Groenen, A. G., Nollet, E. E., Wichapong, K., Lutgens, E., van der Poll, T., Du, J., Wiersinga, W. J., Nicolaes, G. A. F., & van 't Veer, C. (2024). The IRAK-M death domain: a tale of three surfaces. Frontiers in Molecular Biosciences, 10, Article 1265455. https://doi.org/10.3389/fmolb.2023.1265455
- Christ, A., Maas, S. L., Jin, H., Lu, C., Legein, B., Wijnands, E., Temmerman, L., Otten, J., Isaacs, A., Zenke, M., Stoll, M., Biessen, E. A. L., & van der Vorst, E. P. C. (2024). In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naïve T cells. Free Radical Biology and Medicine, 210, 406-415. https://doi.org/10.1016/j.freeradbiomed.2023.11.044
- Simons, J., Di Mauro, M., Mariani, S., Ravaux, J., van der Horst, I. C. C., Driessen, R. G. H., Sels, J. W., Delnoij, T., Brodie, D., Abrams, D., Mueller, T., Taccone, F. S., Belliato, M., Broman, M. L., Malfertheiner, M. V., Boeken, U., Fraser, J., Wiedemann, D., Belohlavek, J., ... Lorusso, R. (2024). Bilateral Femoral Cannulation Is Associated With Reduced Severe Limb Ischemia-Related Complications Compared With Unilateral Femoral Cannulation in Adult Peripheral Venoarterial Extracorporeal Membrane Oxygenation: Results From the Extracorporeal Life Support Registry. Critical Care Medicine, 52(1), 80-91. https://doi.org/10.1097/CCM.0000000000006040
- Mohapatra, A. K., Todaro, A. M., & Castoldi, E. (2024). Factor V variants in bleeding and thrombosis. Research and practice in thrombosis and haemostasis, 8(1), Article 102330. https://doi.org/10.1016/j.rpth.2024.102330
- Halimeh, S., Koch, L., Kenet, G., Kuta, P., Rahmfeld, T., Stoll, M., & Nowak-Göttl, U. (2024). Genotype-Phenotype Relationship among 785 Unrelated White Women with Inherited Congenital Factor VII Deficiency: A Three-Center Database Study. Journal of Clinical Medicine, 13(1), Article 49. https://doi.org/10.3390/jcm13010049
- Baaten, C. C. F. M. J., Nagy, M., Bergmeier, W., Spronk, H. M. H., & van der Meijden, P. E. J. (2024). Platelet biology and function: plaque erosion vs. rupture. European Heart Journal, 45(1), 18-31. https://doi.org/10.1093/eurheartj/ehad720
- Drozdinsky, G., Arad, N., Spectre, G., Livneh, N., Poran, I., Raanani, P., Falanga, A., ten Cate, H., Gafter-Gvili, A., & Leader, A. (2024). Anticoagulation in cancer patients with atrial fibrillation and grade 3–4 thrombocytopenia. Thrombosis Research, 235, 92-97. https://doi.org/10.1016/j.thromres.2024.01.012
- Pijls, N., Joosten, H., Theunissen, M., van Leendert, J., Courtens, A., Magdelijns, F., & Everdingen, M. V. D. B.-V. (2024). Bedside palliative care and geriatric consultations: adherence rate in hospitalised patients. BMJ Supportive and Palliative Care, 14(2), e2011-e2018. https://doi.org/10.1136/spcare-2023-004453
- Emanuel, K. S., Huang, L., Haartmans, M. J. J., Sanmartin Martinez, J., Zijta, F., Heeren, R. M. A., Kerkhoffs, G. M. M. J., Emans, P. J., & Cillero-Pastor, B. (2024). Patient-responsive protein biomarkers for cartilage degeneration and repair identified in the infrapatellar fat pad. Expert Review of Proteomics, 21(12), 563-573. https://doi.org/10.1080/14789450.2024.2438774
- Azzahhafi, J., Chan Pin Yin, D. R., Epping, M., Bofarid, H., Rikken, S. A., Verhagen, T., Boomars, R., Radstok, A., Houtgraaf, J., Bikker, A., & Ten Berg, J. M. (2024). Pre-hospital evaluation of chest pain patients using the modified HEART-score: rationale and design. Future Cardiology, 20(5-6), 241-250. https://doi.org/10.1080/14796678.2024.2356995
- 2023
- Kral, M., van der Vorst, E. P. C., Surnov, A., Weber, C., & Doering, Y. (2023). ILC2-mediated immune crosstalk in chronic (vascular) inflammation. Frontiers in Immunology, 14, Article 1326440. https://doi.org/10.3389/fimmu.2023.1326440
- Mulder, M. M. G., Schellens, J., Sels, J.-W. E. M., van Rosmalen, F., Hulshof, A.-M., de Vries, F., Segers, R., Mihl, C., van Mook, W. N. K. A., Bast, A., Spronk, H. M. H., Henskens, Y. M. C., van der Horst, I. C. C., ten Cate, H., Schurgers, L. J., Drent, M., & van Bussel, B. C. T. (2023). Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort. Journal of Intensive Care, 11(1), Article 63. https://doi.org/10.1186/s40560-023-00712-0
- Bonaca, M. P., Lesén, E., Giannitsis, E., Hedberg, J., Jernberg, T., Lambrelli, D., Duong, M., Maggioni, A. P., Ariza-Solé, A., ten Berg, J., & Storey, R. F. (2023). Characteristics and outcomes in patients with a prior myocardial infarction treated with extended dual antiplatelet therapy with ticagrelor 60 mg: findings from ALETHEIA, a multi-country observational study. European Heart Journal-Cardiovascular Pharmacotherapy, 9(8), 701-708. https://doi.org/10.1093/ehjcvp/pvad062
- van Dam, P. M. E. L., Lievens, S., Zelis, N., van Doorn, W. P. T. M., Meex, S. J. R., Cals, J. W. L., & Stassen, P. M. (2023). Head-to-head comparison of 19 prediction models for short-term outcome in medical patients in the emergency department: a retrospective study. Annals of Medicine, 55(2), Article 2290211. https://doi.org/10.1080/07853890.2023.2290211
- Rikken, S. A. O. F., van 't Hof, A. W. J., Ten Berg, J. M., Kereiakes, D. J., & Coller, B. S. (2023). Critical Analysis of Thrombocytopenia Associated With Glycoprotein IIb/IIIa Inhibitors and Potential Role of Zalunfiban, a Novel Small Molecule Glycoprotein Inhibitor, in Understanding the Mechanism(s). Journal of the American Heart Association, 12(24), Article e031855. https://doi.org/10.1161/JAHA.123.031855
- van Herpt, T. T. W., van Rosmalen, F., Hulsewé, H. P. M. G., van der Horst-Schrivers, A. N. A., Driessen, M., Jetten, R., Zelis, N., de Galan, B. E., van Kuijk, S. M. J., van der Horst, I. C. C., & van Bussel, B. C. T. (2023). Hyperglycemia and glucose variability are associated with worse survival in mechanically ventilated COVID-19 patients: the prospective Maastricht Intensive Care Covid Cohort. Diabetology & Metabolic Syndrome, 15(1), Article 253. https://doi.org/10.1186/s13098-023-01228-1
- Young, W. J., Haessler, J., Benjamins, J. W., Repetto, L., Yao, J., Isaacs, A., Harper, A. R., Ramirez, J., Garnier, S., van Duijvenboden, S., Baldassari, A. R., Concas, M. P., Duong, T. V., Foco, L., Isaksen, J. L., Mei, H., Noordam, R., Nursyifa, C., Richmond, A., ... Et al. (2023). Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease. Nature Communications, 14(1), Article 1411. https://doi.org/10.1038/s41467-023-36997-w
- Sopic, M., Karaduzovic-Hadziabdic, K., Kardassis, D., Maegdefessel, L., Martelli, F., Meerson, A., Munjas, J., Niculescu, L. S., Stoll, M., Magni, P., & Devaux, Y. (2023). Transcriptomic research in atherosclerosis: Unravelling plaque phenotype and overcoming methodological challenges. Journal of Molecular and Cellular Cardiology Plus, 6, Article 100048. https://doi.org/10.1016/j.jmccpl.2023.100048
- Huckriede, J. B., Beurskens, D. M. H., Wildhagen, K. C. C. A., Reutelingsperger, C. P. M., Wichapong, K., & Nicolaes, G. A. F. (2023). Design and characterization of novel activated protein C variants for the proteolysis of cytotoxic extracellular histone H3. Journal of Thrombosis and Haemostasis, 21(12), 3557-3567. https://doi.org/10.1016/j.jtha.2023.08.023
- Verheugt, F. W. A., Fox, K. A. A., Virdone, S., Ambrosio, G., Gersh, B. J., Haas, S., Pieper, K. S., Kayani, G., Camm, A. J., Parkhomenko, A., Misselwitz, F., Ragy, APH., Ten Cate, H., Keltai, M., Kakkar, A. K., & GARFIELD-AF Investigators (2023). Outcomes of Oral Anticoagulation in Atrial Fibrillation Patients with or without Comorbid Vascular Disease: Insights from the GARFIELD-AF Registry. The American Journal of Medicine, 136(12), 1187-1195.e15. https://doi.org/10.1016/j.amjmed.2023.08.019
- Aarts, H. M., van Hemert, N. D., Meijs, T. A., van Nieuwkerk, A. C., Berg, J. M. T., Wykrzykowska, J. J., van Royen, N., Schotborgh, C. E., Tonino, P. A. L., IJsselmuiden, A., Vossenberg, T. N., van Houwelingen, G. K., Slagboom, T., Voskuil, M., & Delewi, R. (2023). Percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis. Netherlands Heart Journal, 31(12), 489–499. Article 31. https://doi.org/10.1007/s12471-023-01824-w




