• 2015
    • Piers, S. R. D., Everaerts, K., van der Geest, R. J., Hazebroek, M. R., Siebelink, H.-M., Pison, L. A. F. G., Schalij, M. J., Bekkers, S. C. A. M., Heymans, S., & Zeppenfeld, K. (2015). Myocardial scar predicts monomorphic ventricular tachycardia but not polymorphic ventricular tachycardia or ventricular fibrillation in nonischemic dilated cardiomyopathy. Heart Rhythm, 12(10), 2106-2114. https://doi.org/10.1016/j.hrthm.2015.05.026
    • Knackstedt, C., Bekkers, S. C. A. M., Schummers, G., Schreckenberg, M., Muraru, D., Badano, L. P., Franke, A., Bavishi, C., Omar, A. M. S., & Sengupta, P. P. (2015). Fully Automated Versus Standard Tracking of Left Ventricular Ejection Fraction and Longitudinal Strain The FAST-EFs Multicenter Study. Journal of the American College of Cardiology, 66(13), 1456-1466. https://doi.org/10.1016/j.jacc.2015.07.052
    • Deckx, S., Carai, P., Bateman, J., Heymans, S., & Papageorgiou, A.-P. (2015). Breeding Strategy Determines Rupture Incidence in Post-Infarct Healing WARPing Cardiovascular Research. PLOS ONE, 10(9), Article e0139199. https://doi.org/10.1371/journal.pone.0139199
    • Hazebroek, M. R., Moors, S., Dennert, R., van den Wijngaard, A., Krapels, I., Hoos, M., Verdonschot, J., Merken, J. J., de Vries, B., Wolffs, P. F., Crijns, H. J. G. M., Brunner-La Rocca, H. P., & Heymans, S. (2015). Prognostic Relevance of Gene-Environment Interactions in Patients With Dilated Cardiomyopathy: Applying the MOGE(S) Classification. Journal of the American College of Cardiology, 66(12), 1313-1323. https://doi.org/10.1016/j.jacc.2015.07.023
    • Blankesteijn, W. M., & Hermans, K. C. M. (2015). Wnt signaling in atherosclerosis. European Journal of Pharmacology, 763, 122-130. https://doi.org/10.1016/j.ejphar.2015.05.023
    • Bartholomé, R., Salden, B., Vrolijk, M. F., Troost, F. J., Masclee, A., Bast, A., & Haenen, G. R. M. M. (2015). Paracetamol as a Post Prandial Marker for Gastric Emptying, A Food-Drug Interaction on Absorption. PLOS ONE, 10(9), Article e0136618. https://doi.org/10.1371/journal.pone.0136618
    • Lemmens, K. J., Herst, P. M., Housmans, B. A., Moalin, M., van der Vijgh, W. J., Bast, A., & Haenen, G. R. (2015). The contribution of the major metabolite 4'-O-methylmonoHER to the antioxidant activity of the flavonoid monoHER. Chemico-Biological Interactions, 239, 146-152. https://doi.org/10.1016/j.cbi.2015.07.004
    • Benedikter, B. J., Volgers, C., Haenen, G. R. M. M., Savelkoul, P. H. M., Wouters, E. F. M., Rohde, G. G. U., Weseler, A. R., & Stassen, F. R. M. (2015). Cigarette smoke extract induces the release of extracellular vesicles by airway epithelial cells via cellular carbonyl stress. European Respiratory Journal, 46(suppl 59). https://doi.org/10.1183/13993003.congress-2015.PA5113
    • Knackstedt, C., Hildebrandt, U., Schmidt, K., Syrocki, L., Lang, A., Bjarnason-Wehrens, B., Schummers, G., Stapf, D., Becker, M., & Predel, H. G. (2015). Analysis of right and left ventricular deformation in former world class swimmers: evaluation using speckle tracking. Journal of Sports Medicine and Physical Fitness, 55(9), 978-987.
    • Cannon, M. V., Sillje, H. H. W., Sijbesma, J. W. A., Vreeswijk-Baudoin, I., Ciapaite, J., van der Sluis, B., van Deursen, J., Silva, G. J. J., de Windt, L. J., Gustafsson, J.-A., van der Harst, P., van Gilst, W. H., & de Boer, R. A. (2015). Cardiac LXR protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization. EMBO Molecular Medicine, 7(9), 1229-1243. https://doi.org/10.15252/emmm.201404669
    • el Azzouzi, H., Leptidis, S., Doevendans, P. A., & De Windt, L. J. (2015). HypoxamiRs: regulators of cardiac hypoxia and energy metabolism. Trends in Endocrinology and Metabolism, 26(9), 502-508. https://doi.org/10.1016/j.tem.2015.06.008
    • Salden, B. N., Monserrat, V., Troost, F. J., Bruins, M. J., Edens, L., Bartholomé, R., Haenen, G. R., Winkens, B., Koning, F., & Masclee, A. A. (2015). Editorial: enhancing gluten digestion in the stomach- a further help to minimise unintentional ingestion? Authors' reply. Alimentary Pharmacology & Therapeutics, 42(4), 485. https://doi.org/10.1111/apt.13296
    • Heymans, S., Gonzalez, A., Pizard, A., Papageorgiou, A. P., Lopez-Andres, N., Jaisser, F., Thum, T., Zannad, F., & Diez, J. (2015). Searching for new mechanisms of myocardial fibrosis with diagnostic and/or therapeutic potential. European journal of heart failure, 17(8), 764-771. https://doi.org/10.1002/ejhf.312
    • Kaufmann, B. A., Goetschalckx, K., Min, S. Y., Maeder, M. T., Bucher, U., Nietlispach, F., Bernheim, A. M., Pfisterer, M. E., Brunner-La Rocca, H. P., & TIME-CHF Investigators, T. (2015). Improvement in left ventricular ejection fraction and reverse remodeling in elderly heart failure patients on intense NT-proBNP-guided therapy. International Journal of Cardiology, 191, 286-293. https://doi.org/10.1016/j.ijcard.2015.04.282
    • Papageorgiou, A.-P., Heggermont, W., Rienks, M., Carai, P., Langouche, L., Verhesen, W., De Boer, R. A., & Heymans, S. (2015). Liver X receptor activation enhances CVB3 viral replication during myocarditis by stimulating lipogenesis. Cardiovascular Research, 107(1), 78-88. https://doi.org/10.1093/cvr/cvv157
    • Tchaikovski, V., Tchaikovski, S., Olieslagers, S., & Waltenberger, J. (2015). Monocyte dysfunction as a previously unrecognized pathophysiological mechanism in ApoE-/- mice contributing to impaired arteriogenesis. International Journal of Cardiology, 190, 214-216. https://doi.org/10.1016/j.ijcard.2015.04.188
    • Devaux, Y., Zangrando, J., Schroen, B., Creemers, E. E., Pedrazzini, T., Chang, C.-P., Dorn, G. W. . II., Thum, T., & Heymans, S. (2015). Long noncoding RNAs in cardiac development and ageing. Nature Reviews Cardiology, 12(7), 415-425. https://doi.org/10.1038/nrcardio.2015.55
    • Hermansand, K. C. M., & Blankesteijn, W. M. (2015). Wnt Signaling in Cardiac Disease. Comprehensive Physiology, 5(3), 1183-1209. https://doi.org/10.1002/cphy.c140060
    • van Empel, V., & Brunner-La Rocca, H. P. (2015). Inflammation in HFpEF: Key or circumstantial?International Journal of Cardiology, 189, 259-263. https://doi.org/10.1016/j.ijcard.2015.04.110
    • Daeichin, V., Akkus, Z., Skachkov, I., Kooiman, K., Needles, A., Sluimer, J., Janssen, B., Daemen, M. J. A. P., van der Steen, A. F. W., de Jong, N., & Bosch, J. G. (2015). Quantification of Bound Microbubbles in Ultrasound Molecular Imaging. Ieee Transactions on Ultrasonics Ferroelectrics and Frequency Control, 62(6), 1190-1200. https://doi.org/10.1109/TUFFC.2015.006264
    • Neumann, D., Luiken, J. J. F. P., Nabben, M., & Glatz, J. F. C. (2015). Letter by Neumann et al Regarding Article, "Myostatin Regulates Energy Homeostasis in the Heart and Prevents Heart Failure". Circulation Research, 116(10), E95-E96. https://doi.org/10.1161/CIRCRESAHA.115.306463
    • Abdurrachim, D., Luiken, J. J. F. P., Nicolay, K., Glatz, J. F. C., Prompers, J. J., & Nabben, M. (2015). Good and bad consequences of altered fatty acid metabolism in heart failure: evidence from mouse models. Cardiovascular Research, 106(2), 194-205. https://doi.org/10.1093/cvr/cvv105
    • Knackstedt, C., Schmidt, K., Syrocki, L., Lang, A., Bjarnason-Wehrens, B., Hildebrandt, U., & Predel, H.-G. (2015). Long-term follow-up of former world-class swimmers: evaluation of cardiovascular function. Heart and Vessels, 30(3), 369-378. https://doi.org/10.1007/s00380-014-0481-z
    • Altara, R., Manca, M., Hermans, K. C., Daskalopoulos, E. P., Brunner-La Rocca, H. P., Hermans, R. J., Struijker-Boudier, H. A. J., & Blankesteijn, M. W. (2015). Diurnal rhythms of serum and plasma cytokine profiles in healthy elderly individuals assessed using membrane based multiplexed immunoassay. Journal of Translational Medicine, 13, Article 129. https://doi.org/10.1186/s12967-015-0477-1
    • Poels, E. M., Martins, P. A. D. C., & van Empel, V. P. M. (2015). Adaptive capacity of the right ventricle: why does it fail?American Journal of Physiology-heart and Circulatory Physiology, 308(8), H803-H813. https://doi.org/10.1152/ajpheart.00573.2014
    • Zurek, M., Maeder, M. T., Rickli, H., Muzzarelli, S., Sanders-van Wijk, S., Abbühl, H., Handschin, R., Jeker, U., Pfisterer, M. E., Brunner-La Rocca, H. P., & TIME-CHF Investigators, T. (2015). Differential Prognostic Impact of Resting Heart Rate in Older Compared With Younger Patients With Chronic Heart Failure: Insights From TIME-CHF. Journal of Cardiac Failure, 21(4), 347-354. https://doi.org/10.1016/j.cardfail.2014.12.014
    • Schalla, S., Jaarsma, C., Bekkers, S. C., Waltenberger, J., Dennert, R., Crijns, H. J., Wildberger, J., Heymans, S., & Brunner-La Rocca, H. P. (2015). Right ventricular function in dilated cardiomyopathy and ischemic heart disease: assessment with non-invasive imaging. Netherlands Heart Journal, 23(4), 232-240. https://doi.org/10.1007/s12471-015-0673-x
    • Diaz-Munoz, M. D., Bell, S. E., Fairfax, K., Monzon-Casanova, E., Cunningham, A. F., Gonzalez-Porta, M., Andrews, S. R., Bunik, V. I., Zarnack, K., Curk, T., Heggermont, W. A., Heymans, S., Gibson, G. E., Kontoyiannis, D. L., Ule, J., & Turner, M. (2015). The RNA-binding protein HuR is essential for the B cell antibody response. Nature Immunology, 16(4), 415-425. https://doi.org/10.1038/ni.3115
    • Brunner-La Rocca, H. P., & Crijns, H. J. (2015). Iron i.v. in heart failure: ready for implementation?European Heart Journal, 36(11), 645-647. https://doi.org/10.1093/eurheartj/ehu392
    • Duygu, B., & Martins, P. A. D. C. (2015). miR-21: a star player in cardiac hypertrophy. Cardiovascular Research, 105(3), 235-237. https://doi.org/10.1093/cvr/cvv026
    • Gandhi, P. U., Motiwala, S. R., Belcher, A. M., Gaggin, H. K., Weiner, R. B., Baggish, A. L., Fiuzat, M., Rocca, H.-P. B.-L., & Januzzi, J. L. . J. (2015). Galectin-3 and mineralocorticoid receptor antagonist use in patients with chronic heart failure due to left ventricular systolic dysfunction. American Heart Journal, 169(3), 404-411. https://doi.org/10.1016/j.ahj.2014.12.012
    • Berry, M., Galinier, M., Delmas, C., Fournier, P., Desmoulin, F., Turkieh, A., Mischak, H., Mullen, W., Barutaut, M., Eurlings, L. W., Van Wijk, S., Rocca, H.-P. B.-L., Caubere, C., Butler, J., Roncalli, J., Evaristi, M. F., Cohen-Solal, A., Seronde, M.-F., Escamilla, R., ... Rouet, P. (2015). Proteomics analysis reveals IGFBP2 as a candidate diagnostic biomarker for heart failure. International Journal of Cardiology - Metabolic & Endocrine, 6, 5-12. https://doi.org/10.1016/j.ijcme.2014.11.003
    • Ounzain, S., Micheletti, R., Beckmann, T., Schroen, B., Alexanian, M., Pezzuto, I., Crippa, S., Nemir, M., Sarre, A., Johnson, R., Dauvillier, J., Burdet, F., Ibberson, M., Guigo, R., Xenarios, I., Heymans, S., & Pedrazzini, T. (2015). Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs. European Heart Journal, 36(6), 353–368. https://doi.org/10.1093/eurheartj/ehu180
    • Kornmann, L. M., Zernecke, A., Curfs, D. M. J., Janssen, B. J. A., Weber, C., de Winther, M. P. J., Reneman, R. S., Hoeks, A. P. G., & Reesink, K. D. (2015). Echogenic perfluorohexane-loaded macrophages adhere in vivo to activated vascular endothelium in mice, an explorative study. Cardiovascular Ultrasound, 13, Article 1. https://doi.org/10.1186/1476-7120-13-1
    • Vrolijk, M. F., Haenen, G. R., Opperhuizen, A., Jansen, E. H., Schiffers, P. M., & Bast, A. (2015). The supplement-drug interaction of quercetin with tamsulosin on vasorelaxation. European Journal of Pharmacology, 746, 132-137. https://doi.org/10.1016/j.ejphar.2014.11.006
    • Van Wijk, S., Van Empel, V., Davarzani, N., Maeder, M. T., Muzzarelli, S., Jeker, U., Dieterle, T., Handschin, R., Kiencke, S., Pfisterer, M. E., Brunner-La Rocca, H. P., & investigators, F. T. TIME.-CHF. (2015). Circulating biomarkers of distinct pathophysiological pathways in heart failure with preserved vs. reduced left ventricular ejection fraction. European journal of heart failure, 17(10), 1006-1014. https://doi.org/10.1002/ejhf.414
    • Cardinaels, E. P. M., Daamen, M. A. M. J., Bekers, O., ten Kate, J., Niens, M., van Suijlen, J. D. E., van Dieijen-Visser, M. P., Brunner-La Rocca, H. P., Schols, J. M. G. A., & Mingels, A. M. A. (2015). Clinical Interpretation of Elevated Concentrations of Cardiac Troponin T, but Not Troponin I, in Nursing Home Residents. Journal of the American Medical Directors Association, 16(10), 884-891. https://doi.org/10.1016/j.jamda.2015.06.026
    • Vrolijk, M. F., Haenen, G., Bast, A., Opperhuizen, A., & Jansen, E. (2015). Een voorbeeld van onderbelichte geneesmiddel-voedingssupplement interactie. Orthostatische hypotensie door tamsulosine en quercetine. PiL, 2015(3), 20-23. https://www.pil-nascholing.nl/tijdschrift/editie/artikel/t/een-voorbeeld-van-onderbelichte-geneesmiddel-voedingssupplement-interactie
    • Brunner-La Rocca, H. P., Knackstedt, C., Eurlings, L., Rolny, V., Krause, F., Pfisterer, M. E., Tobler, D., Rickenbacher, P., Maeder, M. T., & TIME-CHF Investigators, T. (2015). Impact of worsening renal function related to medication in heart failure. European journal of heart failure, 17(2), 159-168. https://doi.org/10.1002/ejhf.210
    • Balk, J. M., Haenen, G. R. M., Koc, O. M., Peters, R., Bast, A., van der Vijgh, W. J. F., & Koek, G. H. (2015). Once-daily dose regimen of ribavirin is interchangeable with a twice-daily dose regimen: randomized open clinical trial. Pharmacogenomics and personalized medicine, 8, 137-144. https://doi.org/10.2147/pgpm.s82782
    • van Aelst, L. N., Voss, S., Carai, P., van Leeuwen, R., Vanhoutte, D., Sanders-van Wijk, S., Eurlings, L., Swinnen, M., Verheyen, F. K., Verbeken, E., Nef, H., Troidl, C., Cook, S. A., Brunner-La Rocca, H. P., Möllmann, H., Papageorgiou, A. P., & Heymans, S. (2015). Osteoglycin prevents cardiac dilatation and dysfunction after myocardial infarction through infarct collagen strengthening. Circulation Research, 116(3), 425-436. https://doi.org/10.1161/CIRCRESAHA.116.304599
    • Salden, B., Monserrat, V., Troost, F. J., Bruins, M. J., Edens, L., Bartholomé, R., Haenen, G. R., Winkens, B., Koning, F., & Masclee, A. A. (2015). Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. Alimentary Pharmacology & Therapeutics, 42(3), 273-285. https://doi.org/10.1111/apt.13266
    • Varon, C., Alao, M., Mintert, J., Stapleton, M., Thomson, S., Jaecques, S., Brunner-La Rocca, H. P., & Huffel, S. V. (2015). Telehealth on heart failure: results of the Recap project. Journal of Telemedicine and Telecare, 21(6), 340-347. https://doi.org/10.1177/1357633X15577310
    • Lemmens, K., van de Wier, B., Koek, G. H., Köhler, E. S., Drittij, M. J., van der Vijgh, W., Bast, A., & Haenen, G. R. (2015). The flavonoid monoHER promotes the adaption to oxidative stress during the onset of NAFLD. Biochemical and Biophysical Research Communications, 456(1), 179-182. https://doi.org/10.1016/j.bbrc.2014.11.055
    • Vrolijk, M. F., Opperhuizen, A., Jansen, E. H., Godschalk, R. W., van Schooten, F. J., Bast, A., & Haenen, G. R. (2015). The shifting perception on antioxidants: The case of vitamin E and beta-carotene. Redox Biology, 4C, 272-278. https://doi.org/10.1016/j.redox.2014.12.017
    • Bryant, C. E., Gay, N. J., Heymans, S., Sacre, S., Schaefer, L., & Midwood, K. S. (2015). Advances in Toll-like receptor biology: Modes of activation by diverse stimuli. Critical Reviews in Biochemistry and Molecular Biology, 50(5), 359-379. https://doi.org/10.3109/10409238.2015.1033511
    • Daskalopoulos, E. P., Vilaeti, A. D., Barka, E., Mantzouratou, P., Kouroupis, D., Kontonika, M., Tourmousoglou, C., Papalois, A., Pantos, C., Blankesteijn, W. M., Agathopoulos, S., & Kolettis, T. M. (2015). Attenuation of post-infarction remodeling in rats by sustained myocardial growth hormone administration. Growth Factors, 33(4), 250-258. https://doi.org/10.3109/08977194.2015.1072527
    • Brunner-La Rocca, H., & Bektas, S. (2015). Biomarker guided therapy in chronic heart failure. Cardiac Failure Review, 1(2), 96-101. https://doi.org/10.15420/cfr.2015.1.2.96