de Kort, J., Haenen, G. R. M. M., Bast, A., Koek, G. H., & Barnes , E. (2002). Oxidative stress in patients with active HCV infection. Hepatology, 36(4), 743. https://doi.org/10.1053/jhep.2002.35344

Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., Oostveen, R. M., Stalpers, E. M., & Bast, A. (2002). Protection of flavonoids against lipid peroxidation: the structure activity relationship revisited. Free Radical Research, 36(5), 575-581. https://doi.org/10.1080/10715760290025951

Rezk, B. M., Haenen, G. R. M. M., van der Vijgh, W. J. F., & Bast, A. (2002). The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids. Biochemical and Biophysical Research Communications, 295(1), 9-13. https://doi.org/10.1016/S0006-291X(02)00618-6

Dallinga, J. W., Haenen, G. R. M. M., Bast, A., & van Schooten, F. J. (2002). The effect of the trolox equivalent antioxidant capacity (TEAC) in plasma on the formation of 4-aminobiphenylhaemoglobin adducts in smokers. Biomarkers, 7(4), 291-298. https://doi.org/10.1080/13547500210148306

Bast, A., & Haenen, G. R. M. M. (2002). The toxicity of antioxidants and their metabolites. Environmental Toxicology and Pharmacology, 11, 251-258. https://doi.org/10.1016/S1382-6689(01)00118-1

Haenen, G. R. M. M., & Bast, A. (2002). The use of vitamin supplements in self-medication. Therapie, 57(2), 119-122. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12185958&dopt=Abstract

van Haaften, R. I. M., Haenen, G. R. M. M., Evelo, C. T. A., & Bast, A. (2002). Tocotrienols inhibit human glutathione S-transferase P1-1. Iubmb Life, 54(2), 81-84. https://doi.org/10.1080/15216540214315

van Eickels, M., Grohé, C., Cleutjens, J. P., Janssen, B. J., Wellens, H. J., & Doevendans, P. A. (2001). 17beta-estradiol attenuates the development of pressure-overload hypertrophy. Circulation, 104(12), 1419-23. https://doi.org/10.1161/hc3601.095577

Blankesteijn, W. M., Creemers, E., Lutgens, E., Cleutjens, J. P., Daemen, M. J., & Smits, J. F. (2001). Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice. Acta Physiologica Scandinavica, 173(1), 75-82. https://doi.org/10.1046/j.1365-201X.2001.00887.x

van Gijn, M. E., Snel, F., Cleutjens, J. P., Smits, J. F., & Blankesteijn, W. M. (2001). Overexpression of components of the Frizzled-Dishevelled cascade results in apoptotic cell death, mediated by beta-catenin. Experimental Cell Research, 265(1), 46-53. https://doi.org/10.1006/excr.2001.5174

van Haaften, R. I. M., Evelo, C. T. A., Haenen, G. R. M. M., & Bast, A. (2001). alpha-Tocopherol inhibits human glutathione S-transferase pi.Biochemical and Biophysical Research Communications, 280, 631-633. https://doi.org/10.1006/bbrc.2000.4174

Nia, A. B., van Schooten, F. J., Schilderman-Houba, P. A. E. L., de Kok, T. M. C. M., Haenen, G. R. M. M., van Herwijnen, M. H. M., van Agen, E., Pachen, D. M. F. A., & Kleinjans, J. C. S. (2001). A multi-biomarker approach to study the effects of smoking on oxidative DNA damage and repair and antioxidative defense mechanisms.Carcinogenesis, 22, 395-401. https://doi.org/10.1093/carcin/22.3.395

van den Berg, R., van Vliet, T., Broekmans, W. M. R., Cnubben, N. H. P., Vaes, W. H. J., Roza, L., Haenen, G. R. M. M., Bast, A., & van den Berg, H. (2001). A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers.Journal of Nutrition, 131, 1714-1722. https://doi.org/10.1093/jn/131.6.1714

Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., van Acker, F. A. A., van der Vijgh, W. J. F., & Bast, A. (2001). Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups.Toxicology in Vitro, 15, 3-6. https://doi.org/10.1016/S0887-2333(00)00053-9

van Haaften, R. I. M., den Hartog, G. J. M., Evelo, C. T. A., Haenen, G. R. M. M., & Bast, A. (2001). Hypochlorous acid is a potent inhibitor of GST P1-1.Chemico-Biological Interactions, 138, 77-83. https://doi.org/10.1016/S0009-2797(01)00262-9

van Haaften, R. I. M., Evelo, C. T. A., Penders, J., Eijnwachter, M., Haenen, G. R. M. M., & Bast, A. (2001). Inhibition of human glutathione S-transferase P1-1 by tocopherols and alpha-tocopherol derivatives.Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1548, 23-28. https://doi.org/10.1016/S0167-4838(01)00211-4

Arts, M. J. T. J., Haenen, G. R. M. M., Voss, H. P., & Bast, A. (2001). Masking of antioxidant capacity by the interaction of flavonoids with protein.Food and Chemical Toxicology, 39, 787-791. https://doi.org/10.1016/S0278-6915(01)00020-5

van Acker, F. A. A., Hulshof, J., Haenen, G. R. M. M., Menge, W. M. P. B., van der Vijgh, W. J. F., & Bast, A. (2001). New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity.Free Radical Biology and Medicine, 31, 31-37. https://doi.org/10.1016/S0891-5849(01)00546-9

Drent, M., van den Berg, R., Haenen, G. R. M. M., van den Berg, H., Wouters, E. F. M., & Bast, A. (2001). NF-kappaB activation in sarcoidosis.Sarcoidosis Vasculitis and Diffuse Lung Diseases, 18(1), 50-56. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11354547&dopt=Abstract

van Haaften, R. I. M., Evelo, C. T. A., Haenen, G. R. M. M., & Bast, A. (2001). No reduction of alpha-tocopherol quinone by glutathione in rat liver microsomes. Biochemical Pharmacology, 61, 715-719. https://doi.org/10.1016/S0006-2952(01)00545-7

van den Berg, R., Haenen, G. R. M. M., van den Berg, H., & Bast, A. (2001). Nuclear factor-kappaB activation is higher in peripheral blood mononuclear cells of male smokers.Environmental Toxicology and Pharmacology, 9, 147-151. https://doi.org/10.1016/S1382-6689(00)00070-3

Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., Vekemans, J., & Bast, A. (2001). Peroxynitrite scavenging of flavonoids: structure activity relationship. Environmental Toxicology and Pharmacology, 10, 199-206. https://doi.org/10.1016/S1382-6689(01)00083-7

Rhemrev, J. P. T., Vermeiden, J. P. W., Haenen, G. R. M. M., de Bruijne, J., Rekers-Mombarg, L., & Bast, A. (2001). Progressively motile human spermatozoa are well protected against in vitro lipid peroxidation imposed by induced oxidative stress.Andrologia, 33, 151-158. https://doi.org/10.1046/j.1439-0272.2001.00430.x

Ostby, O. B., Gundersen, L. L., Rise, F., Antonson, O., Fosnes, K., Larsen, V., Bast, A., Custers, I., & Haenen, G. R. M. M. (2001). Synthesis of 5-substituted pyrrolo[1,2-b]pyridazines with antioxidant properties. Archiv der Pharmazie, 334, 21-24. https://doi.org/10.1002/1521-4184(200101)334:1<21::AID-ARDP21>3.0.CO;2-W

Keularts, I. M. L. W., Zivelin, A., Seligsohn, U., Hemker, H. C., & Béguin, S. (2001). The role of factor XI in thrombin generation induced by low concentrations of tissue factor.Thrombosis and Haemostasis, 85, 1060-1065. https://doi.org/10.1055/s-0037-1615964

van den Berg, R., Haenen, G. R. M. M., van den Berg, H., & Bast, A. (2001). Transcription factor NF-kappaB as a potential biomarker for oxidative stress.British Journal of Nutrition, 86 suppl 1, S121-S127. https://doi.org/10.1079/BJN2001340

Creemers, E., Cleutjens, J., Smits, J., Heymans, S., Moons, L., Collen, D., Daemen, M., & Carmeliet, P. (2000). Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction. American Journal of Pathology, 156(6), 1865-73. https://doi.org/10.1016/S0002-9440(10)65060-2

van Acker, F. A. A., van Acker, S. A. B. E., Kramer, K., Haenen, G. R. M. M., Bast, A., & van der Vijgh, W. J. F. (2000). 7-monohydroxyethylrutoside protects against chronic doxorubicin-induced cardiotoxicity when administered only once per week. Clinical Cancer Research, 6(4), 1337-1347. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10778960&dopt=Abstract

Keularts, I. M. L. W., van Gorp Beisser, R. M. A., Feijge, M. A. H., Vuist, M. W. J., & Heemskerk, J. W. M. (2000). alpha2A-Adrenergic receptor stimulation potentiates calcium release in platelets by modulating cAMP levels. Journal of Biological Chemistry, 275(3), 1763-1772. https://doi.org/10.1074/jbc.275.3.1763

Heunks, L. M. A., Bast, A., van Herwaarden, C. L. A., Haenen, G. R. M. M., & Dekhuijzen, P. N. R. (2000). Effects of emphysema and training on glutathione oxidation in the hamster diaphragm. Journal of Applied Physiology, 88, 2054-2061. https://doi.org/10.1152/jappl.2000.88.6.2054

van Acker, F. A. A., Schouten, O., Haenen, G. R. M. M., van der Vijgh, W. J. F., & Bast, A. (2000). Flavonoids can replace alpha-tocopherol as an antioxidant. Febs Letters, 473, 145-148. https://doi.org/10.1016/S0014-5793(00)01517-9

van Acker, F. A. A., van Acker, S. A. B. E., Haenen, G. R. M. M., Bast, A., & van der Vijgh, W. J. F. (2000). In vitro screening of antitumour agents for cardiotoxicity by means of isolated mouse left atria. Anticancer Research, 20(6B), 4483-4487. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11205292&dopt=Abstract

Paquay, J. B. G., Haenen, G. R. M. M., Stender, G., Wiseman, S. A., Tijburg, L. B. M., & Bast, A. (2000). Protection against nitric oxide toxicity by tea. Journal of Agricultural and Food Chemistry, 48, 5768-5772. https://doi.org/10.1021/jf981316h

Rhemrev, J. P. T., van Overveld, F. W. P. C., Haenen, G. R. M. M., Teerlink, T., Bast, A., & Vermeiden, J. P. W. (2000). Quantification of the nonenzymatic fast and slow TRAP in a postaddition assay in human seminal plasma and the antioxidant contributions of various seminal compounds. Journal of Andrology, 21, 913-920. https://doi.org/10.1002/j.1939-4640.2000.tb03422.x

Vreman, H. J., Haenen, G. R. M. M., Stevenson, D. K., & Bast, A. (2000). Reduction of the NO-mediated response in the rat aorta by metalloporphyrins. Canadian Journal of Physiology and Pharmacology, 78, 457-461. https://doi.org/10.1139/y00-009

Ystby, O. B., Dalhus, B., Gundersen, L. L., Rise, F., Bast, A., & Haenen, G. R. M. M. (2000). Synthesis of 1-substituted 7-cyano-2,3-diphenylindolizines and evaluation of antioxidant properties. European Journal of Organic Chemistry, 3763-3770. https://doi.org/10.1002/1099-0690(200011)2000:22<3763::AID-EJOC3763>3.0.CO;2-S

van Acker, F. A. A., Hageman, G. J., Haenen, G. R. M. M., van der Vijgh, W. J. F., Bast, A., & Menge, W. M. P. B. (2000). Synthesis of novel 3,7-substituted-2-(3',4'-dihydroxyphenyl)flavones with improved antioxidant activity. Journal of Medicinal Chemistry, 43, 3752-3760. https://doi.org/10.1021/jm000951n

Keularts, I. M. L. W., Hamulyak, K., Hemker, H. C., & Béguin, S. (2000). The effect of DDAVP infusion On thrombin generation in platelet-rich plasma of von Willebrand type 1 and in mild haemophilia A patients. Thrombosis and Haemostasis, 84(4). https://doi.org/10.1055/s-0037-1614080

Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., Wiseman, S. A., & Tijburg, L. B. M. (2000). The interaction of tea flavonoids with the NO-system: disrimination between good and bad NO. Food Chemistry, 70, 365-370. https://doi.org/10.1016/S0308-8146(00)00105-9

van den Berg, R., Haenen, G. R. M. M., van den Berg, H., van der Vijgh, W. J. F., & Bast, A. (2000). The predictive value of the antioxidant capacity of structurally related flavonoids using the Trolox equivalent antioxidant capacity TEAC assay. Food Chemistry, 70, 391-395. https://doi.org/10.1016/S0308-8146(00)00092-3

Vliet, L. A., Rodenhuis, N., Wikstrom, H., Pugsley, T. A., Serpa, K. A., Meltzer, L. T., Heffner, T. G., Wise, L. D., Laijness, M. E., Huff, R. M., Svensson, K., Haenen, G. R. M. M., & Bast, A. (2000). Thiazoloindans and thiazolobenzopyrans: a novel class of orally active central dopamine (partial) agonists. Journal of Medicinal Chemistry, 43, 3549-3557. https://doi.org/10.1021/jm000087z

van Overveld, F. W. P. C., Haenen, G. R. M. M., Rhemrev, J. P. T., Vermeiden, J. P. W., & Bast, A. (2000). Tyrosine as important contributor to the antioxidant capacity of seminal plasma. Chemico-Biological Interactions, 127, 151-161. https://doi.org/10.1016/S0009-2797(00)00179-4

Cleutjens, J. P., Blankesteijn, W. M., Daemen, M. J., & Smits, J. F. (1999). The infarcted myocardium: simply dead tissue, or a lively target for therapeutic interventions. Cardiovascular Research, 44(2), 232-41. https://doi.org/10.1016/s0008-6363(99)00212-6

Heymans, S., Luttun, A., Nuyens, D., Theilmeier, G., Creemers, E., Moons, L., Dyspersin, G. D., Cleutjens, J. P., Shipley, M., Angellilo, A., Levi, M., Nübe, O., Baker, A., Keshet, E., Lupu, F., Herbert, J. M., Smits, J. F., Shapiro, S. D., Baes, M., ... Carmeliet, P. (1999). Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure. Nature Medicine, 5(10), 1135-42. https://doi.org/10.1038/13459

van den Berg, R., Haenen, G. R. M. M., van den Berg, H., & Bast, A. (1999). Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures.Food Chemistry, 66(4), 511-518. https://doi.org/10.1016/S0308-8146(99)00089-8

Haenen, G. R. M. M., & Bast, A. (1999). Nitric Oxide Radical Scavenging of Flavonoids. Methods in Enzymology, 301, 490-503. https://doi.org/10.1016/S0076-6879(99)01112-X

Paquay, J. B. G., Hoen, P. A., Bast, A., Timmerman, H., & Haenen, G. R. M. M. (1999). Nitric oxide synthase inhibition by dimaprit and dimaprit analogues.British Journal of Pharmacology, 127(2), 331-334. https://doi.org/10.1038/sj.bjp.0702552

Beguin, S., Kumar, R., Keularts, I., Seligsohn, U., Coller, B. S., & Hemker, H. C. (1999). Fibrin-dependent platelet procoagulant activity requires GPIb receptors and von Willebrand factor. Blood, 93(2), 564-570. https://doi.org/10.1182/blood.V93.2.564