Heggermont, W. A., & Heymans, S. (2012). MicroRNAs Are Involved in End-Organ Damage During Hypertension. Hypertension, 60(5), 1088-1093. https://doi.org/10.1161/HYPERTENSIONAHA.111.187104

Bourgonje, V. J. A., Schoenmakers, M., Beekman, J. D. M., van der Nagel, R., Houtman, M. J. C., Miedema, L. F., Antoons, G., Sipido, K., de Windt, L. J., van Veen, T. A. B., & Vos, M. A. (2012). Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog. Heart Rhythm, 9(11), 1875-1883.e2. https://doi.org/10.1016/j.hrthm.2012.07.023

Rickenbacher, P., Pfisterer, M., Burkard, T., Kiowski, W., Follath, F., Burckhardt, D., Schindler, R., & Rocca, H.-P. B.-L. (2012). Why and how do elderly patients with heart failure die? Insights from the TIME-CHF study. European journal of heart failure, 14(11), 1218-1229. https://doi.org/10.1093/eurjhf/hfs113

Eurlings, L. W., van Wijk, S., van Kimmenade, R., Osinski, A., van Helmond, L., Vallinga, M., Crijns, H. J., van Dieijen-Visser, M. P., Brunner La Rocca, H. P., & Pinto, Y. M. (2012). Multimarker strategy for short-term risk assessment in patients with dyspnea in the emergency department: The marked (multi marker emergency dyspnea)-risk score. Journal of the American College of Cardiology, 60(17), 1668-1677. https://doi.org/10.1016/j.jacc.2012.06.040

Nelissen, J., Lemkens, P., Sann, H., Bindl, M., Bassissi, F., Jasserand, D., De Mey, J. G. R., & Janssen, B. J. A. (2012). Pharmacokinetic and pharmacodynamic properties of SOL1: A novel dual inhibitor of neutral endopeptidase and endothelin converting enzyme. Life Sciences, 91(13-14), 587-592. https://doi.org/10.1016/j.lfs.2012.01.015

Lemkens, P., Nelissen, J., Meens, M. J. P. M. T., Janssen, B. J. A., Schiffers, P. M. H., & De Mey, J. G. R. (2012). Dual neural peptidase/endothelin-converting enzyme inhibition improves endothelial function in mesenteric resistance arteries of young spontaneously hypertensive rats. Journal of Hypertension, 30(9), 1799-1808. https://doi.org/10.1097/HJH.0b013e3283569c7a

Totzeck, M., Hendgen-Cotta, U. B., Rammos, C., Frommke, L.-M., Knackstedt, C., Predel, H.-G., Kelm, M., & Rassaf, T. (2012). Higher endogenous nitrite levels are associated with superior exercise capacity in highly trained athletes. Nitric Oxide-Biology and Chemistry, 27(2), 75-81. https://doi.org/10.1016/j.niox.2012.05.003

Knackstedt, C., Becker, M., Mischke, K., Pauling, R., Rocca, H. P. B.-L., & Schauerte, P. (2012). A dedicated cardioversion unit for the treatment of atrial fibrillation. Reducing costs by optimizing processes. Herz, 37(5), 518-526. https://doi.org/10.1007/s00059-011-3546-0

Dennert, R., van Paassen, P., Wolffs, P., Bruggeman, C., Velthuis, S., Felix, S., van Suylen, R.-J., Crijns, H. J., Tervaert, J. W. C., & Heymans, S. (2012). Differences in Virus Prevalence and Load in the Hearts of Patients with Idiopathic Dilated Cardiomyopathy with and without Immune-Mediated Inflammatory Diseases. Clinical and Vaccine Immunology, 19(8), 1182-1187. https://doi.org/10.1128/CVI.00281-12

Hazebroek, M., Dennert, R., & Heymans, S. (2012). Idiopathic dilated cardiomyopathy: possible triggers and treatment strategies. Netherlands Heart Journal, 20(7-8), 332-335. https://doi.org/10.1007/s12471-012-0285-7

Timmers, S., Nabben, M., Bosma, M., van Bree, B., Lenaers, E., Van Beurden, D., Schaart, G., Westerterp-Plantenga, M. S., Langhans, W., Hesselink, M. K. C., Schrauwen-Hinderling, V. B., & Schrauwen, P. (2012). Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America, 109(29), 11711-11716. https://doi.org/10.1073/pnas.1206868109

Corsten, M. F., Schroen, B., & Heymans, S. (2012). Inflammation in viral myocarditis: friend or foe?Trends in Molecular Medicine, 18(7), 426-437. https://doi.org/10.1016/j.molmed.2012.05.005

Boots, A. W., Gerloff, K., Bartholomé, R., van Berlo, D., Ledermann, K., Haenen, G. R. M. M., Bast, A., van Schooten, F. J., Albrecht, C., & Schins, R. P. (2012). Neutrophils augment LPS-mediated pro-inflammatory signaling in human lung epithelial cells. Biochimica et Biophysica Acta-Molecular Cell Research, 1823(7), 1151-1162. https://doi.org/10.1016/j.bbamcr.2012.04.012

Altenhofer, S., Kleikers, P. W. M., Radermacher, K. A., Scheurer, P., Hermans, J. J. R., Schiffers, P., Ho, H., Wingler, K., & Schmidt, H. H. H. W. (2012). The NOX toolbox: validating the role of NADPH oxidases in physiology and disease. Cellular and Molecular Life Sciences, 69(14), 2327-2343. https://doi.org/10.1007/s00018-012-1010-9

el Azzouzi, H., Leptidis, S., Bourajjaj, M., van Bilsen, M., Martins, P. A. D. C., & De Windt, L. J. (2012). MEK1 Inhibits Cardiac PPAR alpha Activity by Direct Interaction and Prevents Its Nuclear Localization. PLOS ONE, 7(6), Article e36799. https://doi.org/10.1371/journal.pone.0036799

Daamen, M. A. M. J., Hamers, J. P. H., Gorgels, A. P. M., Brunner-La Rocca, H. P., Tan, F. E. S., van Dieijen-Visser, M. P., & Schols, J. M. G. A. (2012). The prevalence and management of heart failure in Dutch nursing homes: design of a multi-centre cross-sectional study. BMC Geriatrics, 12, Article 29. https://doi.org/10.1186/1471-2318-12-29

Salic, K., & De Windt, L. J. (2012). MicroRNAs as Biomarkers for Myocardial Infarction. Current Atherosclerosis Reports, 14(3), 193-200. https://doi.org/10.1007/s11883-012-0238-z

Fransen, G. A. J., Mesters, I., Muris, J. W. M., Van Marrewijk, C. J., Mujakovic, S., Laheij, R. J. F., Numans, M. E., De Wit, N. J., Samsom, M., Jansen, J. B. M. J., & Knottnerus, J. A. (2012). Patient adherence to prescribed medication instructions for dyspepsia: The DIAMOND-study. European Journal of General Practice, 18(2), 79-85. https://doi.org/10.3109/13814788.2012.665443

Tivig, C., Dang, L., Brunner-La Rocca, H.-P., Oezcan, S., Duru, F., & Scharf, C. (2012). Duty-cycled unipolar/bipolar versus conventional radiofrequency ablation in paroxysmal and persistent atrial fibrillation. International Journal of Cardiology, 157(2), 185-191. https://doi.org/10.1016/j.ijcard.2010.12.010

Hazewindus, M., Haenen, G. R. M. M., Weseler, A. R., & Bast, A. (2012). The anti-inflammatory effect of lycopene complements the antioxidant action of ascorbic acid and alpha-tocopherol. Food Chemistry, 132(2), 954-958. https://doi.org/10.1016/j.foodchem.2011.11.075

Papageorgiou, A.-P., & Heymans, S. (2012). Interactions between the extracellular matrix and inflammation during viral myocarditis. Immunobiology, 217(5), 503-510. https://doi.org/10.1016/j.imbio.2011.07.011

Seemann, I., Gabriels, K., Visser, N. L., Hoving, S., te Poele, J. A., Pol, J. F., Gijbels, M. J., Janssen, B. J., Van Leeuwen, F. W., Daemen, M. J., Heeneman, S., & Stewart, F. A. (2012). Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature. Radiotherapy and Oncology, 103(2), 143-150. https://doi.org/10.1016/j.radonc.2011.10.011

Donners, M. M. P. C., Wolfs, I. M. J., Stoger, L. J., van der Vorst, E. P. C., Pottgens, C. C. H., Heymans, S., Schroen, B., Gijbels, M. J. J., & de Winther, M. P. J. (2012). Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice. PLOS ONE, 7(4), Article e35877. https://doi.org/10.1371/journal.pone.0035877

Papageorgiou, A.-P., Swinnen, M., Vanhoutte, D., VandenDriessche, T., Chuah, M., Lindner, D., Verhesen, W., de Vries, B., D'hooge, J., Lutgens, E., Westermann, D., Carmeliet, P., & Heymans, S. (2012). Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory T-cells. Cardiovascular Research, 94(1), 115-124. https://doi.org/10.1093/cvr/cvs077

Jin, Y., Kuznetsova, T., Thijs, L., Schmitz, B., Liu, Y., Asayama, K., Brand, S.-M., Heymans, S., Brand, E., Fagard, R., & Staessen, J. A. (2012). Association of Left Ventricular Mass With the AGTR1 A1166C Polymorphism. American Journal of Hypertension, 25(4), 472-478. https://doi.org/10.1038/ajh.2011.244

Martins, P. A. D. C., & De Windt, L. J. (2012). MicroRNAs in control of cardiac hypertrophy. Cardiovascular Research, 93(4), 563-572. https://doi.org/10.1093/cvr/cvs013

Schroen, B., & Heymans, S. (2012). Small but smart-microRNAs in the centre of inflammatory processes during cardiovascular diseases, the metabolic syndrome, and ageing. Cardiovascular Research, 93(4), 605-613. https://doi.org/10.1093/cvr/cvr268

Muzzarelli, S., Maeder, M. T., Toggweiler, S., Rickli, H., Nietlispach, F., Julius, B., Burkard, T., Pfisterer, M. E., & Brunner-La Rocca, H.-P. (2012). Frequency and Predictors of Hyperkalemia in Patients >= 60 Years of Age With Heart Failure Undergoing Intense Medical Therapy. American Journal of Cardiology, 109(5), 693-698. https://doi.org/10.1016/j.amjcard.2011.10.027

Burkard, T., Kaiser, C. A., Brunner-La Rocca, H., Osswald, S., Pfisterer, M. E., & Jeger, R. V. (2012). Combined clopidogrel and proton pump inhibitor therapy is associated with higher cardiovascular event rates after percutaneous coronary intervention: a report from the BASKET trial. Journal of Internal Medicine, 271(3), 257-263. https://doi.org/10.1111/j.1365-2796.2011.02423.x

Maeder, M. T., Rickli, H., Pfisterer, M. E., Muzzarelli, S., Ammann, P., Fehr, T., Hack, D., Weilenmann, D., Dieterle, T., Kiencke, S., Estlinbaum, W., & Brunner-La Rocca, H.-P. (2012). Incidence, clinical predictors, and prognostic impact of worsening renal function in elderly patients with chronic heart failure on intensive medical therapy. American Heart Journal, 163(3), 407-U353. https://doi.org/10.1016/j.ahj.2011.12.003

Devaux, Y., Vausort, M., Goretti, E., Nazarov, P. V., Azuaje, F., Gilson, G., Corsten, M. F., Schroen, B., Lair, M.-L., Heymans, S., & Wagner, D. R. (2012). Use of Circulating MicroRNAs to Diagnose Acute Myocardial Infarction. Clinical Chemistry, 58(3), 559-567. https://doi.org/10.1373/clinchem.2011.173823

Zellweger, M. J., Kaiser, C. A., Jeger, R. V., Brunner-La Rocca, H.-P., Buser, P. T., Bader, F., Mueller-Brand, J., & Pfisterer, M. E. (2012). Coronary Artery Disease Progression Late After Successful Stent Implantation. Journal of the American College of Cardiology, 59(9), 793-799. https://doi.org/10.1016/j.jacc.2011.11.024

Daskalopoulos, E. P., Janssen, B. J. A., & Blankesteijn, W. M. (2012). Myofibroblasts in the Infarct Area: Concepts and Challenges. Microscopy and Microanalysis, 18(1), 35-49. https://doi.org/10.1017/S143192761101227X

Heijman, J., Spätjens, R. L. H., Seyen, S. R. M., Lentink, V., Kuijpers, H. J. H., Boulet, I. R., de Windt, L. J., David, M., & Volders, P. G. A. (2012). Dominant-Negative Control of cAMP-Dependent I-Ks Upregulation in Human Long-QT Syndrome Type 1. Circulation Research, 110(2), 211–219. https://doi.org/10.1161/CIRCRESAHA.111.249482

Octavia, Y., Rocca, H. P. B.-L., & Moens, A. L. (2012). NADPH oxidase-dependent oxidative stress in the failing heart: From pathogenic roles to therapeutic approach. Free Radical Biology and Medicine, 52(2), 291-297. https://doi.org/10.1016/j.freeradbiomed.2011.10.482

Moalin, M., van Strijdonck, G. P., Bast, A., & Haenen, G. R. M. M. (2012). Competition between Ascorbate and Glutathione for the Oxidized Form of Methylated Quercetin Metabolites and Analogues: Tamarixetin, 4'O-Methylquercetin, Has the Lowest Thiol Reactivity. Journal of Agricultural and Food Chemistry, 60(36), 9292-9297. https://doi.org/10.1021/jf302068v

Mateo Anson, N., Hemery, Y. M., Bast, A., & Haenen, G. R. M. M. (2012). Optimizing the bioactive potential of wheat bran by processing. Food & Function, 3(4), 362-375. https://doi.org/10.1039/c2fo10241b

van den Heuvel, M. G. W., Bast, A., Haenen, G. R. M. M., Ambergen, A. W., Mermans, J. F., & van der Hulst, R. R. W. J. (2012). The role of antioxidants in ischaemia-reperfusion in a human DIEP flap model. Journal of Plastic Reconstructive and Aesthetic Surgery, 65(12), 1706-1711. https://doi.org/10.1016/j.bjps.2012.06.010

van Wijk, S., Jacobs, L., Eurlings, L. W., van Kimmenade, R., Lemmers, R., Broos, P., Bekers, O., Prins, M. H., Crijns, H. J., Pinto, Y. M., van Dieijen-Visser, M. P., & Brunner-La Rocca, H. P. (2012). Troponin T Measurements by High-Sensitivity vs Conventional Assays for Risk Stratification in Acute Dyspnea. Clinical Chemistry, 58(1), 284-292. https://doi.org/10.1373/clinchem.2011.175976

Gladka, M. M., Martins, P. A. D. C., & de Windt, L. J. (2012). Small changes can make a big difference - MicroRNA regulation of cardiac hypertrophy. Journal of Molecular and Cellular Cardiology, 52(1), 74-82. https://doi.org/10.1016/j.yjmcc.2011.09.015

ter Horst, P., Smits, J. F. M., & Blankesteijn, W. M. (2012). The Wnt/Frizzled pathway as a therapeutic target for cardiac hypertrophy: where do we stand. Acta Physiologica, 204(1), 110-117. https://doi.org/10.1111/j.1748-1716.2011.02309.x

Halbach, N. S. J., Smeets, E. E. J., Bierau, J., Keularts, I. M. L. W., Plasqui, G., Julu, P. O. O., Engerström, I. W., Bakker, J. A., & Curfs, L. M. G. (2012). Altered carbon dioxide metabolism and creatine abnormalities in rett syndrome. JIMD reports, 3, 117-24. https://doi.org/10.1007/8904_2011_76

Spijkers, L. J. A., Janssen, B. J. A., Nelissen, J., Meens, M. J. P. M. T., Wijesinghe, D. S., Chalfant, C. E., De Mey, J. G. R., Alewijnse, A. E., & Peters, S. L. M. (2011). Antihypertensive Treatment Differentially Affects Vascular Sphingolipid Biology in Spontaneously Hypertensive Rats. PLOS ONE, 6(12), Article e29222. https://doi.org/10.1371/journal.pone.0029222

Nabben, M., Hoeks, J., Kornips, C. F. P., Van Beurden, D., Briedé, J. J., Hesselink, M. K. C., Glatz, J. F., & Schrauwen, P. (2011). Significance of uncoupling protein 3 in mitochondrial function upon mid- and long-term dietary high-fat exposure. Febs Letters, 585(24), 4010-4017. https://doi.org/10.1016/j.febslet.2011.11.012

Weseler, A. R., Ruijters, E. J. B., Reesink, K. D., Haenen, G. R. M. M., & Bast, A. (2011). Pleiotropic benefit of monomeric and oligomeric flavanols on vascular health - a randomized controlled clinical pilot study. PLOS ONE, 6(12), Article 28460. https://doi.org/10.1371/journal.pone.0028460

Jacobs, H., Moalin, M., van Gisbergen, M. W., Bast, A., van der Vijgh, W. J. F., & Haenen, G. R. M. M. (2011). An essential difference in the reactivity of the glutathione adducts of the structurally closely related flavonoids monoher and quercetin. Free Radical Biology and Medicine, 51(11), 2118-2123. https://doi.org/10.1016/j.freeradbiomed.2011.09.013

Jacobs, H., Koek, G. H., Peters, R., Moalin, M., Tack, J., van der Vijgh, W. J. F., Bast, A., & Haenen, G. R. M. M. (2011). Differences in pharmacological activities of the antioxidant flavonoid monoher in humans and mice are caused by variations in its metabolic profile. Clinical Pharmacology & Therapeutics, 90(6), 852-859. https://doi.org/10.1038/clpt.2011.200

Bartelds, B., Borgdorff, M. A., Smit-van Oosten, A., Takens, J., Boersma, B., Nederhoff, M. G., Elzenga, N. J., van Gilst, W. H., De Windt, L. J., & Berger, R. M. F. (2011). Differential responses of the right ventricle to abnormal loading conditions in mice: pressure vs. volume load. European journal of heart failure, 13(12), 1275-1282. https://doi.org/10.1093/eurjhf/hfr134

He, B. J., Joiner, M. A., Singh, M. V., Luczak, E. D., Swaminathan, P. D., Koval, O. M., Kutschke, W., Allamargot, C., Yang, J., Guan, X., Zimmerman, K., Grumbach, I. M., Weiss, R. M., Spitz, D. R., Sigmund, C. D., Blankesteijn, W. M., Heymans, S., Mohler, P. J., & Anderson, M. E. (2011). Oxidation of CaMKII determines the cardiotoxic effects of aldosterone. Nature Medicine, 17(12), 1610-U125. https://doi.org/10.1038/nm.2506