Roberto Lorusso


Prof. Roberto Lorusso studied medicine at the University of Milan, Italy and graduated in 1987 magna cum Laude. He worked at Maastricht UMC+ in 1990 at CTC research and in 1996 and 1997 at the academic Hospital of Leuven. In 1998, he successfully obtained his PhD degree at Maastricht University (thesis titled 'Cardiac reinforcement and assistance by electrically stimulated skeletal muscle').

Currently, Prof. Roberto Lorusso is staff member at the Department of Cardiothoracic Surgery at Maastricht UMC+, Director of the Extracorporeal Life Support (ECLS) Program, Full Professor of Cardiac Surgery and ECLS at the Maastricht University and CARIM. His research group is focussed on mechanical circulatory support, minimally invasive valve surgery, coronary surgery, cardiac valve disease, extracorporeal circulation, acute myocardial infarction complications, cardiac valve disease, preclinical and clinical research.

Prof. Roberto Lorusso won the Gasperis-Donatelli Prize in 1989, a Young Investigator Award in 1995 and the Lillehei Award in 1998 by the European Association for Cardio-Thoracic Surgery.  He was Scientific Secretary of the Italian Society for Cardiac Surgery in 2007 and 2008, President of Euro-ELSO (2015-2017), and he is currently Editor-in-Chief of the Multi-Media Manual of Cardio-Thoracic Surgery as well as member of the ELSO Executive Committee.

He has almost 300 publications in PubMed, and has given more than 300 presentations at international meetings as invited speaker. He is Principal Investigator of international multicentre clinical studies and grant receiver from several funding bodies for clinical as well as pre-clinical investigations.

Department of Cardiothoracic surgery
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: D.2037
T: +31(0)43 387 60 32

  • 2023
    • Tran, A., Rochwerg, B., Fan, E., Belohlavek, J., Suverein, M. M., van de Poll, M. C. G., Lorusso, R., Price, S., Yannopoulos, D., MacLaren, G., Ramanathan, K., Ling, R. R., Thiara, S., Tonna, J. E., Shekar, K., Hodgson, C. L., Scales, D. C., Sandroni, C., Nolan, J. P., ... Fernando, S. M. (2023). Prognostic factors associated with favourable functional outcome among adult patients requiring extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: A systematic review and meta-analysis. Resuscitation, 193, Article 110004.
    • Koulouroudias, M., Di Mauro, M., & Lorusso, R. (2023). Long term outcomes of bioprosthetic valves in the mitral position. A systematic review of studies published over the last 20 years. European Journal of Cardio-Thoracic Surgery, Article ezad384.
    • Martucci, G., Giani, M., Schmidt, M., Tanaka, K., Tabatabai, A., Tuzzolino, F., Agerstrand, C., Riera, J., Ramanan, R., Grasselli, G., Ait Hssain, A., Gannon, W. D., Buabbas, S., Gorjup, V., Trethowan, B., Rizzo, M., Fanelli, V., Jeon, K., De Pascale, G., ... International ECMO Network (ECMONet) (2023). Anticoagulation and Bleeding during Veno-Venous Extracorporeal Membrane Oxygenation: Insights from the PROTECMO Study. American Journal of Respiratory and Critical Care Medicine. Advance online publication.
    • Brewer, J. M., Broman, L. M., Swol, J., Lorusso, R., Conrad, S. A., & Maybauer, M. O. (2023). Standardized nomenclature for peripheral percutaneous cannulation of the pulmonary artery in extracorporeal membrane oxygenation: Current uptake and recommendations for improvement. Perfusion, 2676591231210457. Advance online publication.
    • Mariani, S., Schaefer, A-K., van Bussel, B. C. T., Di Mauro, M., Conci, L., Szalkiewicz, P., De Piero, M. E., Heuts, S., Ravaux, J., van der Horst, I. C. C., Saeed, D., Pozzi, M., Loforte, A., Boeken, U., Samalavicius, R., Bounader, K., Hou, X., Bunge, J. J. H., Buscher, H., ... PELS Investigators (2023). On-Support and Postweaning Mortality in Postcardiotomy Extracorporeal Membrane Oxygenation. The Annals of thoracic surgery, 116(5), 1079-1089.
    • Byrne, R. A., Rossello, X., Coughlan, J. J., Barbato, E., Berry, C., Chieffo, A., Claeys, M. J., Dan, G-A., Dweck, M. R., Galbraith, M., Gilard, M., Hinterbuchner, L., Jankowska, E. A., Juni, P., Kimura, T., Kunadian, V., Leosdottir, M., Lorusso, R., Pedretti, R. F. E., ... ESC Scientific Document Group (2023). 2023 ESC Guidelines for the management of acute coronary syndromes. European Heart Journal, 44(38), 3720-3826. Article ehad191.
    • Formica, F., Vaquero, D. H., Tuttolomondo, D., Gallingani, A., Singh, G., Pattuzzi, C., Niccoli, G., Lorusso, R., & Nicolini, F. (2023). Results beyond 5-years of surgery or percutaneous approach in severe coronary disease. Reconstructed time-to-event meta-analysis of randomized trials. Revista espanola de cardiologia (English Edition). Advance online publication.
    • Fernando, S. M., MacLaren, G., Barbaro, R. P., Mathew, R., Munshi, L., Madahar, P., Fried, J. A., Ramanathan, K., Lorusso, R., Brodie, D., & McIsaac, D. I. (2023). Age and associated outcomes among patients receiving venoarterial extracorporeal membrane oxygenation-analysis of the Extracorporeal Life Support Organization registry. Intensive Care Medicine. Advance online publication.
    • Szuldrzynski, K., Kowalewski, M., Jankowski, M., Staromlynski, J., Prokop, J., Pasierski, M., Chudzinski, K., Drobinski, D., Martucci, G., Lorusso, R., Wierzba, W., Zaczynski, A., Krol, Z., & Suwalski, P. (2023). Effects of adding the second drainage cannula in severely hypoxemic patients supported with VV ECMO due to COVID-19-associated ARDS. Artificial Organs, 47(10), 1622-1631.
    • Low, C. J. W., Ramanathan, K., Ling, R. R., Ho, M. J. C., Chen, Y., Lorusso, R., MacLaren, G., Shekar, K., & Brodie, D. (2023). Extracorporeal cardiopulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with cardiac arrest: a comparative meta-analysis and trial sequential analysis. The Lancet Respiratory medicine, 11(10), 883-893.
    • Raasveld, S. J., Karami, M., Schenk, J., Dos Reis Miranda, D., Mandigers, L., Dauwe, D. F., De Troy, E., Pappalardo, F., Fominskiy, E., van den Bergh, W. M., Oude Lansink-Hartgring, A., van der Velde, F., Maas, J. J., van de Berg, P., de Haan, M., Donker, D. W., Meuwese, C. L., Taccone, F. S., Peluso, L., ... Vlaar, A. P. J. (2023). Transfusion of red blood cells in venoarterial extracorporeal membrane oxygenation: A multicenter retrospective observational cohort study. Transfusion, 63(10), 1809-1820.
    • Ronco, D., Ariza-Solé, A., Kowalewski, M., Matteucci, M., Di Mauro, M., López-de-Sá, E., Ranucci, M., Sionis, A., Bonaros, N., De Bonis, M., Russo, C. F., Uribarri, A., Montero, S., Fischlein, T., Kowalówka, A., Naito, S., Obadia, J-F., Martín-Asenjo, R., Aboal, J., ... Lorusso, R. (2023). The current clinical practice for management of post-infarction ventricular septal rupture: a European survey. European heart journal open, 3(5), Article oead091.
    • Simons, J., Di Mauro, M., Mariani, S., Ravaux, J., van der Horst, I. C. C., Driessen, R. G. H., Sels, J. W., Delnoij, T., Brodie, D., Abrams, D., Mueller, T., Taccone, F. S., Belliato, M., Broman, M. L., Malfertheiner, M. V., Boeken, U., Fraser, J., Wiedemann, D., Belohlavek, J., ... Lorusso, R. (2023). Bilateral Femoral Cannulation Is Associated With Reduced Severe Limb Ischemia-Related Complications Compared With Unilateral Femoral Cannulation in Adult Peripheral Venoarterial Extracorporeal Membrane Oxygenation: Results From the Extracorporeal Life Support Registry. Critical Care Medicine. Advance online publication.
    • Koziol, K. J., Isath, A., Rao, S., Gregory, V., Ohira, S., Van Diepen, S., Lorusso, R., & Krittanawong, C. (2023). Extracorporeal Membrane Oxygenation (VA-ECMO) in Management of Cardiogenic Shock. Journal of Clinical Medicine, 12(17), Article 5576.
    • Di Nardo, M., Moreau, A., Annoni, F., Su, F., Belliato, M., Broman, L. M., Malfertheiner, M., Lorusso, R., & Taccone, F. S. (2023). Evaluation of a new magnetically suspended centrifugal neonatal pump in healthy animals using a veno-venous extracorporeal membrane oxygenation configuration. Perfusion, Article 02676591231202380. Advance online publication.
    • Tie, H., Li, T., Huang, B., Mariani, S., Li, T., van Bussel, B. C. T., Wu, Q., Pei, J., Welp, H., Martens, S., Li, Z., Shi, R., Zhu, J., Luo, S., Lichtenberg, A., Aubin, H., Boeken, U., Lorusso, R., & Dan, C. (2023). Presence and impact of anemia in patients supported with left ventricular assist devices. Journal of Heart and Lung Transplantation, 42(9), 1261-1274.
    • van Haeren, M. M. T., Raasveld, S. J., Karami, M., Miranda, D. D. R., Mandigers, L., Dauwe, D. F., De Troy, E., Pappalardo, F., Fominskiy, E., van den Bergh, W. M., Oude Lansink-Hartgring, A., van der Velde, F., Maas, J. J., van de Berg, P., de Haan, M., Donker, D. W., Meuwese, C. L., Taccone, F. S., Peluso, L., ... Müller, M. C. A. (2023). Plasma Transfusion and Procoagulant Product Administration in Extracorporeal Membrane Oxygenation: A Secondary Analysis of an International Observational Study on Current Practices. Critical care explorations, 5(8), Article 0949.
    • Raasveld, S. J., van den Oord, C., Schenk, J., van den Bergh, W. M., Oude Lansink-Hartgring, A., van der Velde, F., Maas, J. J., van de Berg, P., Lorusso, R., Delnoij, T. S. R., Dos Reis Miranda, D., Scholten, E., Taccone, F. S., Dauwe, D. F., De Troy, E., Hermans, G., Pappalardo, F., Fominskiy, E., Ivancan, V., ... Vlaar, A. P. J. (2023). The interaction of thrombocytopenia, hemorrhage, and platelet transfusion in venoarterial extracorporeal membrane oxygenation: a multicenter observational study. Critical Care, 27(1), Article 321.
    • Kuzma, L., Kowalewski, M., Wanha, W., Dabrowski, E. J., Jasinski, M., Widenka, K., Deja, M., Bartus, K., Hirnle, T., Wojakowski, W., Lorusso, R., Tobota, Z., Maruszewski, B. J., Suwalski, P., & KROK Investigators (2023). Validation of EuroSCORE II in atrial fibrillation heart surgery patients from the KROK Registry. Scientific Reports, 13(1), Article 13024.
    • Zaaqoq, A. M., Griffee, M. J., Kelly, T. L., Fanning, J. P., Heinsar, S., Suen, J. Y., Mariani, S., Li Bassi, G., Jacobs, J. P., White, N., Fraser, J. F., Lorusso, R., Peek, G. J., Cho, S. M., & COVID-19 Critical Care Consortium (2023). Cerebrovascular Complications of COVID-19 on Venovenous Extracorporeal Membrane Oxygenation. Critical Care Medicine, 51(8), 1043-1053.
    • Ganizada, B. H., Reesink, K. D., Parikh, S., Ramaekers, M. J. F. G., Akbulut, A. C., Saraber, P. J. M. H., Debeij, G. P., Jaminon, A. M., Natour, E., Lorusso, R., Wildberger, J. E., Mees, B., Schurink, G. W., Jacobs, M. J., Cleutjens, J., Krapels, I., Gombert, A., Maessen, J. G., Accord, R., ... MUMC TAA Student Team (2023). The Maastricht Acquisition Platform for Studying Mechanisms of Cell-Matrix Crosstalk (MAPEX): An Interdisciplinary and Systems Approach towards Understanding Thoracic Aortic Disease. Biomedicines, 11(8), Article 2095.
    • Massimi, G., Matteucci, M., De Bonis, M., Kowalewski, M., Formica, F., Russo, C. F., Sponga, S., Vendramin, I., Colli, A., Falcetta, G., Trumello, C., Carrozzini, M., Fischlein, T., Troise, G., Dato, G. A., D'Alessandro, S., Nia, P. S., Lodo, V., Villa, E., ... Lorusso, R. (2023). Extracorporeal life support in mitral papillary muscle rupture: Outcome of multicenter study. Artificial Organs, 47(8), 1386-1394.
    • Lazar, H., Suwalski, P., Lorusso, R., Meani, P., & Kowalewski, M. (2023). Topical vancomycin for sternal wound infection prophylaxis. Reinventing the wheel all over again. Annals of Thoracic Surgery, 116(2), 440-441.
    • Hwang, J., Kalra, A., Shou, B. L., Whitman, G., Wilcox, C., Brodie, D., Zaaqoq, A. M., Lorusso, R., Uchino, K., & Cho, S-M. (2023). Epidemiology of Ischemic Stroke and Hemorrhagic Stroke in Venoarterial Extracorporeal Membrane Oxygenation. Research Square. Advance online publication.
    • Ubben, J. F. H., Heuts, S., Delnoij, T. S. R., Suverein, M. M., van de Koolwijk, A. F., van der Horst, I. C. C., Maessen, J. G., Bartos, J., Kavalkova, P., Rob, D., Yannopoulos, D., Belohlávek, J., Lorusso, R., & van de Poll, M. C. G. (2023). ECPR for refractory OHCA - lessons from 3 randomized controlled trials. The trialists´view. European Heart Journal: Acute Cardiovascular Care, 12(8), 540-547. Article zuad071.
    • Mariani, S., Heuts, S., van Bussel, B. C. T., Di Mauro, M., Wiedemann, D., Saeed, D., Pozzi, M., Loforte, A., Boeken, U., Samalavicius, R., Bounader, K., Hou, X., Bunge, J. J. H., Buscher, H., Salazar, L., Meyns, B., Herr, D., Matteucci, M. L. S., Sponga, S., ... PELS-1 Investigators (2023). Patient and Management Variables Associated With Survival After Postcardiotomy Extracorporeal Membrane Oxygenation in Adults: The PELS-1 Multicenter Cohort Study. Journal of the American Heart Association, 12(14), Article 029609.
    • van de Koolwijk, A. F., Ubben, J. F. H., Suverein, M. M., Lorusso, R., & van de Poll, M. C. G. (2023). Extracorporeal cardiopulmonary resuscitation success-System or selection?Resuscitation, 188, Article 109827.
    • Mauri, T., Spinelli, E., Ibrahim, Q., Rochwerg, B., Lorusso, R., Tonna, J. E., Price, S., MacLaren, G., Pesenti, A., Slutsky, A. S., & Brodie, D. (2023). Impact of Drainage Cannula Size and Blood Flow Rate on the Outcome of Patients Receiving Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: An ELSO Registry Analysis. American Journal of Respiratory and Critical Care Medicine, 208(1), 105-107.
    • Formica, F., Gallingani, A., Tuttolomondo, D., Hernandez-Vaquero, D., Singh, G., Pattuzzi, C., Maestri, F., Niccoli, G., Ceccato, E., Lorusso, R., & Nicolini, F. (2023). Long-Term Outcomes Comparison Between Surgical and Percutaneous Coronary Revascularization in Patients With Multivessel Coronary Disease or Left Main Disease: A Systematic Review and Study Level Meta-Analysis of Randomized Trials. Current Problems in Cardiology, 48(7), Article 101699.
    • Heuts, S., Mariani, S., van Bussel, B. C. T., Boeken, U., Samalavicius, R., Bounader, K., Hou, X., Bunge, J. J. H., Sriranjan, K., Wiedemann, D., Saeed, D., Pozzi, M., Loforte, A., Salazar, L., Meyns, B., Mazzeffi, M. A., Matteucci, S., Sponga, S., Sorokin, V., ... PELS-1 Investigators (2023). The Relation Between Obesity and Mortality in Postcardiotomy Venoarterial Membrane Oxygenation. Annals of Thoracic Surgery, 116(1), 147-154.
    • Cucchi, M., Mariani, S., De Piero, M. E., Ravaux, J. M., Kawczynski, M. J., Di Mauro, M., Shkurka, E., Hoskote, A., & Lorusso, R. (2023). Awake extracorporeal life support and physiotherapy in adult patients: A systematic review of the literature. Perfusion, 38, 939-958.
    • Willers, A., Mariani, S., Maessen, J. M., Lorusso, R., & Swol, J. (2023). Extracorporeal life support in thoracic emergencies-a narrative review of current evidence. Journal of Thoracic Disease, 15(7), 4076-4089.
    • Olek, E., Pasierski, M., Slomka, A., Raffa, G. M., Lebowitz, S. E., Pilato, M., Szuldrzynski, K., Suwalski, P., Lorusso, R., & Kowalewski, M. (2023). Blood product transfusions on extracorporeal membrane oxygenation: a narrative review. Annals of Blood, 8, Article 16.
    • Matteucci, M., Ferrarese, S., Kowalewski, M., Meani, P., Messina, C., Giusti, R., Velasco, M., Scarantino, A., Garis, S., Borsani, P., Corazzari, C., Ronco, D., Lorusso, R., Severgnini, P., & Musazzi, A. (2023). Surgical repair of postinfarction ventricular septal rupture: current state of the art. Minerva Surgery, 78(3), 293-299.
    • Sala, A., Carino, D., Lorusso, R., Zancanaro, E., Bargagna, M., Del Forno, B., Trumello, C., Denti, P., Ruggeri, S., Nonis, A., Scarale, M. G., Schiavi, D., Castiglioni, A., Maisano, F., Alfieri, O., & De Bonis, M. (2023). TRI-SCORE: a single-centre validation study. Interdisciplinary CardioVascular and Thoracic Surgery, 36(6), Article ivad085.
    • Suverein, M. M., Lorusso, R., & van de Poll, M. C. G. (2023). Extracorporeal CPR for Out-of-Hospital Cardiac Arrest. Reply. New England Journal of Medicine, 388(20), 1913-1917.
    • Rahouma, M., Baudo, M., Khairallah, S., Dabsha, A., Tafuni, A., Ahmed, M. E-S. M., Lau, C., Iannacone, E., Naka, Y., Girardi, L., Gaudino, M., Lorusso, R., & Mick, S. L. (2023). Primary Cardiac Schwannoma: A Meta-Analysis of Individual Case Reports. Journal of Clinical Medicine, 12(10), Article 3356.
    • Ascione, G., Guicciardi, N. A., Lorusso, R., Boccellino, A., Lapenna, E., Del Forno, B., Carino, D., Bisogno, A., Palmisano, A., D'Angelo, G., Della Bella, P., Esposito, A., Agricola, E., Alfieri, O., Castiglioni, A., Maisano, F., Vergara, P., & De Bonis, M. (2023). The impact of mitral valve surgery on ventricular arrhythmias in patients with Barlow's disease: preliminary results of a prospective study. Interdisciplinary CardioVascular and Thoracic Surgery, 36(5), Article ivad073.
    • Mauri, T., Spinelli, E., Ibrahim, Q., Rochwerg, B., Lorusso, R., Tonna, J., Price, S., MacLaren, G., Pesenti, A., Slutsky, A., & Brodie, D. (2023). Blood Flow Rate and Drainage Cannula Size Impact the Outcome of Patients Receiving VV-ECMO for ARDS. American Journal of Respiratory and Critical Care Medicine, 207.
    • Lorusso, R., De Piero, M. E., Mariani, S., & Di Mauro, M. (2023). Determinants of long-term outcomes in patients with COVID-19 supported with ECMO. The Lancet Respiratory medicine, 11(5), e42.
    • Scquizzato, T., Yannopoulos, D., Belohlavek, J., Taccone, F. S., Lorusso, R., Scandroglio, A. M., Landoni, G., & Swol, J. (2023). Extracorporeal CPR after the INCEPTION trial: No one steps twice into the same river. Artificial Organs, 47(5), 802-805.
    • Di Nardo, M., MacLaren, G., Schellongowski, P., Azoulay, E., DeZern, A. E., Gutierrez, C., Antonelli, M., Antonini, M., Beutel, G., Combes, A., Diaz, R., Hassan, I. F., Fowles, J-A., Jeong, I-S., Kochanek, M., Liebregts, T., Lueck, C., Moody, K., Moore, J. A., ... Brodie, D. (2023). Extracorporeal membrane oxygenation in adults receiving haematopoietic cell transplantation: an international expert statement. The Lancet Respiratory medicine, 11(5), 477-492.
    • Squiccimarro, E., Colombaro, C., Civita, A., Rociola, R., Buys, D., Gesualdo, L., Paparella, D., & Lorusso, R. (2023). Addressing inadequate blood flow during normothermic regional perfusion for in-situ donation after circulatory death grafts preservation. Perfusion, 38, 54-58.
    • Fleig, M., Müller, T., Antonini, V. M., Riera, J., Belliato, M., Broman, L. M., Fowles, J. A., Belohlavek, J., Lorusso, R., Vercaemst, L., Jones, T., Roeleveld, P. P., Di Nardo, M., Barrett, N., & Swol, J. (2023). Extracorporeal life support provision in COVID-19 patients-An international EuroELSO 2022 update survey. Perfusion, 38, 13-23.
    • Gillon, S., Zheng, C. Y., Feng, Z. Q., Fleig, M., Scquizzato, T., Belohlavek, J., Lorusso, R., Lone, N., & Swol, J. (2023). GEospatial aNalysis of ExtRacorporeal membrane oxygenATion in Europe (GENERATE). Perfusion, 38(1_SUPPL), 24-39.
    • Simons, J., Doddema, A. R., Korver, E. P. J., di Mauro, M., Agricola, S., Smets, J., Metz, R., Mariani, S., De Piero, M. E., Matteucci, M., Romeo, J., Ravaux, J. M., van Mook, W. N. K. A., Mees, B. M. E., & Lorusso, R. (2023). Novel cannulation strategy with a bidirectional cannula for distal limb perfusion during peripheral veno-arterial extracorporeal life support: A preliminary, single-centre study. Perfusion, 38, 44-53.
    • Brewer, J. M., Capoccia, M., Maybauer, D. M., Lorusso, R., Swol, J., & Maybauer, M. O. (2023). The ProtekDuo dual-lumen cannula for temporary acute mechanical circulatory support in right heart failure: A systematic review. Perfusion, 38, 59-67.
    • Lorusso, R., Martucci, G., Di Mauro, M., & Kowalewski, M. (2023). Upper gastrointestinal bleeding in veno-arterial extracorporeal membrane oxygenation patients: a neglected (sometimes hidden) enemy deserving further investigation and action. European Journal of Cardio-Thoracic Surgery, 63(4), Article ezad148.
    • Costantini, S., Belliato, M., Ferrari, F., Gazzaniga, G., Ravasi, M., Manera, M., De Piero, M. E., Curcelli, A., Cardinale, A., & Lorusso, R. (2023). A retrospective analysis of the hemolysis occurrence during extracorporeal membrane oxygenation in a single center. Perfusion, 38(3), 609-621. Article 02676591211073768.
    • Condello, I., Santarpino, G., Nasso, G., Moscarelli, M., Speziale, G., & Lorusso, R. (2023). 'Goal-directed extracorporeal circulation: transferring the knowledge and experience from daily cardiac surgery to extracorporeal membrane oxygenation'. Perfusion, 38(3), 449-454. Article 02676591211063826.