Roberto Lorusso


Prof. Roberto Lorusso studied medicine at the University of Milan, Italy and graduated in 1987 magna cum Laude. He worked at Maastricht UMC+ in 1990 at CTC research and in 1996 and 1997 at the academic Hospital of Leuven. In 1998, he successfully obtained his PhD degree at Maastricht University (thesis titled 'Cardiac reinforcement and assistance by electrically stimulated skeletal muscle').

Currently, Prof. Roberto Lorusso is staff member at the Department of Cardiothoracic Surgery at Maastricht UMC+, Director of the Extracorporeal Life Support (ECLS) Program, Full Professor of Cardiac Surgery and ECLS at the Maastricht University and CARIM. His research group is focussed on mechanical circulatory support, minimally invasive valve surgery, coronary surgery, cardiac valve disease, extracorporeal circulation, acute myocardial infarction complications, cardiac valve disease, preclinical and clinical research.

Prof. Roberto Lorusso won the Gasperis-Donatelli Prize in 1989, a Young Investigator Award in 1995 and the Lillehei Award in 1998 by the European Association for Cardio-Thoracic Surgery.  He was Scientific Secretary of the Italian Society for Cardiac Surgery in 2007 and 2008, President of Euro-ELSO (2015-2017), and he is currently Editor-in-Chief of the Multi-Media Manual of Cardio-Thoracic Surgery as well as member of the ELSO Executive Committee.

He has almost 300 publications in PubMed, and has given more than 300 presentations at international meetings as invited speaker. He is Principal Investigator of international multicentre clinical studies and grant receiver from several funding bodies for clinical as well as pre-clinical investigations.

Department of Cardiothoracic surgery
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: D.2037
T: +31(0)43 387 60 32

  • 2021
    • Swol, J., Brodie, D., Willers, A., Zakhary, B., Belezzo, J., Shinar, Z., Weingart, S. D., Haft, J. W., Lorusso, R., & Peek, G. J. (2021). Human factors in ECLS - A keystone for safety and quality - A narrative review for ECLS providers. Artificial Organs.
    • Lorusso, R., Mariani, S., & Ravaux, J. M. (2021). Gently handling the acutely failing right ventricle ... at last!Interactive Cardiovascular and Thoracic Surgery, 33(5), 801-802.
    • Lorusso, R., Ravaux, J. M., & Mariani, S. (2021). Left ventricular assist devices and right ventricular failure prediction: Quo Vadis?Interactive Cardiovascular and Thoracic Surgery, 33(5), 793-794.
    • Di Mauro, M., Calafiore, A. M., & Lorusso, R. (2021). All roads lead to Rome, but some are safer. Journal of Cardiac Surgery, 36(11), 4320-4321.
    • Ravaux, J. M., Mariani, S., & Lorusso, R. (2021). Predictors of permanent pacemaker implantation following surgical aortic valve replacement: Letter to the editor-Reply. Journal of Cardiac Surgery, 36(11), 4444-4444.
    • Ronco, D., Matteucci, M., Kowalewski, M., De Bonis, M., Formica, F., Jiritano, F., Fina, D., Folliguet, T., Bonaros, N., Russo, C. F., Sponga, S., Vendramin, I., De Vincentiis, C., Ranucci, M., Suwalski, P., Falcetta, G., Fischlein, T., Troise, G., Villa, E., ... Lorusso, R. (2021). Surgical Treatment of Postinfarction Ventricular Septal Rupture. Jama network open, 4(10), [e2128309].
    • Heinsar, S., Jung, J. S., Colombo, S. M., Rozencwajg, S., Wildi, K., Sato, K., Ainola, C., Wang, X. M., Abbate, G., Sato, N., Dyer, W. B., Livingstone, S. A., Pimenta, L. P., Bartnikowski, N., Bouquet, M. J. P., Passmore, M., Vidal, B., Palmieri, C., Reid, J. D., ... Fraser, J. F. (2021). An innovative ovine model of severe cardiopulmonary failure supported by veno-arterial extracorporeal membrane oxygenation. Scientific Reports, 11(1), [20458].
    • Gaudino, M., Sandner, S., Di Giammarco, G., Di Franco, A., Arai, H., Asai, T., Bakaeen, F., Doenst, T., Fremes, S. E., Glineur, D., Kieser, T. M., Lawton, J. S., Lorusso, R., Patel, N., Puskas, J. D., Tatoulis, J., Taggart, D. P., Vallely, M., & Ruel, M. (2021). The Use of Intraoperative Transit Time Flow Measurement for Coronary Artery Bypass Surgery Systematic Review of the Evidence and Expert Opinion Statements. Circulation, 144(14), 1160-1171.
    • Extracorporeal Life Support Organization (2021). Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry. Lancet, 398(10307), 1230-1238.
    • Sciatti, E., Mohseni, Z., Orabona, R., Mulder, E. G., Prefumo, F., Lorusso, R., Frusca, T., Ghossein-Doha, C., & Spaanderman, M. E. A. (2021). Maternal myocardial dysfunction after hemolysis, elevated liver enzymes, and low platelets syndrome: a speckle-tracking study. Journal of Hypertension, 39(10), 1956-1963.
    • Jiritano, F., Fina, D., Lorusso, R., ten Cate, H., Kowalewski, M., Matteucci, M., Serra, R., Mastroroberto, P., & Serraino, G. F. (2021). Systematic review and meta-analysis of the clinical effectiveness of point-of-care testing for anticoagulation management during ECMO. Journal of Clinical Anesthesia, 73, [110330].
    • Ravaux, J. M., Van Kuijk, S. M. J., Di Mauro, M., Vernooy, K., Bidar, E., Mariani, S., Dato, G. A., Van't Hof, A. W., Veenstra, L., Kats, S., Houterman, S., Maessen, J. G., Lorusso, R., & Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration (2021). Incidence and predictors of permanent pacemaker implantation after surgical aortic v alve replacement: Data of the Netherlands Heart Registration (NHR). Journal of Cardiac Surgery, 36(10), 3519-3527.
    • Matteucci, M., Ferrarese, S., Mantovani, V., Ronco, D., Torchio, F., Franzosi, C., Marazzato, J., De Ponti, R., Lorusso, R., & Beghi, C. (2021). Surgical treatment of primary cardiac tumors in the contemporary era: A single-centre analysis. Journal of Cardiac Surgery, 36(10), 3540-3546.
    • Makhoul, M., Heuts, S., Mansouri, A., Taccone, F. S., Obeid, A., Mirko, B., Broman, L. M., Malfertheiner, M. V., Meani, P., Raffa, G. M., Delnoij, T., Maessen, J., Bolotin, G., & Lorusso, R. (2021). Understanding the "extracorporeal membrane oxygenation gap" in veno-arterial configuration for adult patients: Timing and causes of death. Artificial Organs, 45(10), 1155-1167.
    • Bonalumi, G., Giambuzzi, I., Lorusso, R., & Di Mauro, M. (2021). Whatever happens, two mammary is better than one. Journal of Cardiac Surgery, 36(10), 3639-3640.
    • Euro-ELSO Working Grp Neurologic M (2021). International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe. Perfusion, [02676591211042563].
    • Ronco, D., Matteucci, M., & Lorusso, R. (2021). REPLY: Temporary Mechanical Circulatory Support in Postinfarct Ventricular Septal Defect Time for an Upgrade?Jacc-Cardiovascular Interventions, 14(17), 1955-1956.
    • Abrams, D., MacLaren, G., Lorusso, R., Price, S., Yannopoulos, D., Vercaemst, L., Belohlavek, J., Taccone, F. S., Aissaoui, N., Shekar, K., Garan, A. R., Uriel, N., Tonna, J. E., Jung, J. S., Takeda, K., Chen, Y. S., Slutsky, A. S., Combes, A., & Brodie, D. (2021). Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications. Intensive Care Medicine.
    • Heuts, S., Makhoul, M., Mansouri, A. N., Taccone, F. S., Obeid, A., Belliato, M., Broman, L. M., Malfertheiner, M., Meani, P., Raffa, G. M., Delnoij, T., Maessen, J., Bolotin, G., & Lorusso, R. (2021). Defining and understanding the "extra-corporeal membrane oxygenation gap" in the veno-venous configuration: Timing and causes of death. Artificial Organs.
    • Nasso, G., Lorusso, R., Motekallemi, A., Dell'Aquila, A. M., Di Bari, N., Condello, I., Moscarelli, M., Iacopino, S., Serraino, G. F., Mastroroberto, P., Santarpino, G., & Speziale, G. (2021). The fate of patients after failed epicardial ablation of atrial fibrillation. Journal of Cardiothoracic Surgery, 16(1), [249].
    • Matteucci, M., Formica, F., Kowalewski, M., Massimi, G., Ronco, D., Beghi, C., & Lorusso, R. (2021). Meta-analysis of surgical treatment for postinfarction left ventricular free-wall rupture. Journal of Cardiac Surgery, 36(9), 3326-3333.
    • Mariani, S., Napp, L. C., Kraaier, K., Li, T., Bounader, K., Hanke, J. S., Dogan, G., Schmitto, J. D., & Lorusso, R. (2021). Prophylactic mechanical circulatory support for protected ventricular tachycardia ablation: A meta-analysis of the literature. Artificial Organs, 45(9), 987-997.
    • Sala, A., Lorusso, R., Bargagna, M., Ruggeri, S., Buzzatti, N., Scandroglio, M., Monaco, F., Agricola, E., Giacomini, A., Carino, D., Meneghin, R., Schiavi, D., Lapenna, E., Denti, P., Blasio, A., Alfieri, O., Castiglioni, A., & De Bonis, M. (2021). Complicated postoperative course in isolated tricuspid valve surgery: Looking for predictors. Journal of Cardiac Surgery, 36(9), 3092-3099.
    • Heuts, S., Ubben, J. F., Banks-Gonzales, V., Sels, J-W., Lorusso, R., van Mook, W. N. K. A., & Delnoij, T. S. R. (2021). Nitric Oxide Ventilation Improves Recirculation and Right Ventricular Function During Veno-Venous Extracorporeal Membrane Oxygenation in a COVID-19 Patient. Journal of Cardiothoracic and Vascular Anesthesia, 35(9), 2763-2767.
    • Lorusso, R., & Mueller, T. (2021). COVID-19 and ECMO: a call for close cooperation and more investigation. The Lancet Respiratory medicine, 9(8), 805-807.
    • Broman, L. M., Eksborg, S., Lo Coco, V., Piero, M. E., Belohlavek, J., Lorusso, R., EuroECMO, C. O. V. I. D., & EuroECMO COVID-19 Working Group (2021). Extracorporeal membrane oxygenation for COVID-19 during first and second waves. The Lancet Respiratory medicine, 9(8), E80-E81.
    • Willers, A., Arens, J., Mariani, S., Pels, H., Maessen, J. G., Hackeng, T. M., Lorusso, R., & Swol, J. (2021). New Trends, Advantages and Disadvantages in Anticoagulation and Coating Methods Used in Extracorporeal Life Support Devices. Membranes, 11(8), [617].
    • Kaddoura, R., Omar, A. S., Ibrahim, M. I. M., Alkhulaifi, A., Lorusso, R., Elsherbini, H., Soliman, O., & Caliskan, K. (2021). The Effectiveness of Levosimendan on Veno-Arterial Extracorporeal Membrane Oxygenation Management and Outcome: A Systematic Review and Meta-Analysis. Journal of Cardiothoracic and Vascular Anesthesia, 35(8), 2483-2495.
    • Chiarini, G., Cho, S-M., Whitman, G., Rasulo, F., & Lorusso, R. (2021). Brain Injury in Extracorporeal Membrane Oxygenation: A Multidisciplinary Approach. Seminars in Neurology, 41(04), 422-436.
    • Lorusso, R., Shekar, K., MacLaren, G., Schmidt, M., Pellegrino, V., Meyns, B., Haft, J., Vercaemst, L., Pappalardo, F., Bermudez, C., Belohlavek, J., Hou, X., Boeken, U., Castillo, R., Donker, D. W., Abrams, D., Ranucci, M., Hryniewicz, K., Chavez, I., ... Combes, A. (2021). ELSO Interim Guidelines for Venoarterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients. Asaio Journal, 67(8), 827-844.
    • Mariani, S., Li, T., Boethig, D., Napp, L. C., Chatterjee, A., Homann, K., Bounader, K., Hanke, J. S., Dogan, G., Lorusso, R., Bauersachs, J., Haverich, A., & Schmitto, J. D. (2021). Lateral Thoracotomy for Ventricular Assist Device Implantation: A Meta-Analysis of Literature. Asaio Journal, 67(8), 845-854.
    • Kurniawati, E. R., Rutjens, V. G. H., Vranken, N. P. A., Delnoij, T. S. R., Lorusso, R., van der Horst, I. C. C., Maessen, J. G., & Weerwind, P. W. (2021). Quality of life following adult veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review. Quality of Life Research, 30(8), 2123-2135.
    • van der Boon, R. M. A., den Dekker, W. K., Meuwese, C. L., Lorusso, R., von der Thusen, J. H., Constantinescu, A. C., Manintveld, O. C., Delnoij, T. S. R., van der Heijden, J. J., van Mieghem, N. M. D. A., & den Uil, C. A. (2021). Safety of Endomyocardial Biopsy in New-Onset Acute Heart Failure Requiring Veno-Arterial Extracorporeal Membrane Oxygenation. Circulation-Heart Failure, 14(8), [008387].
    • Lorusso, R., Lo Coco, V., & Mariani, S. (2021). Left ventricular assist device and right ventricular dysfunction: how to predict and manage a potentially perilous path?European Journal of Cardio-Thoracic Surgery, 60(1), 186-188.
    • Kowalewski, M., Zielinski, K., Brodie, D., MacLaren, G., Whitman, G., Raffa, G. M., Boeken, U., Shekar, K., Chen, Y-S., Bermudez, C., D'Alessandro, D., Hou, X., Haft, J., Belohlavek, J., Dziembowska, I., Suwalski, P., Alexander, P., Barbaro, R. P., Gaudino, M., ... Lorusso, R. (2021). Venoarterial Extracorporeal Membrane Oxygenation for Postcardiotomy Shock-Analysis of the Extracorporeal Life Support Organization Registry*. Critical Care Medicine, 49(7), 1107-1117.
    • Nasso, G., Lorusso, R., Moscarelli, M., De Martino, G., Dell'Aquila, A. M., Motekallemi, A., Di Bari, N., Condello, I., Mastroroberto, P., Santarpino, G., & Speziale, G. (2021). Catheter, surgical, or hybrid procedure: what future for atrial fibrillation ablation?Journal of Cardiothoracic Surgery, 16(1), [186].
    • Di Nardo, M., Lorusso, R., Guner, Y., Schomberg, J., & De Luca, D. (2021). Feasibility of Lung Ultrasound to Monitor Aeration in Children Supported With Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome. Asaio Journal, 67(6), E104-E106.
    • Suwalski, P., Staromlynski, J., Braczkowski, J., Bartczak, M., Mariani, S., Drobinski, D., Szuldrzynski, K., Smoczynski, R., Franczyk, M., Sarnowski, W., Gajewska, A., Witkowska, A., Wierzba, W., Zaczynski, A., Krol, Z., Olek, E., Pasierski, M., Ravaux, J. M., de Piero, M. E., ... Kowalewski, M. (2021). Transition from Simple V-V to V-A and Hybrid ECMO Configurations in COVID-19 ARDS. Membranes, 11(6), [434].
    • Belliato, M., Cremascoli, L., Epis, F., Ferrari, F., Quattrone, M. G., Malfertheiner, M., Broman, L. M., Aliberti, A., Taccone, F. S., Iotti, G. A., & Lorusso, R. (2021). Carbon Dioxide Elimination During Veno-Venous Extracorporeal Membrane Oxygenation Weaning: A Pilot Study. Asaio Journal, 67(6), 700-708.
    • Mueller, T., Brodie, D., Lorusso, R., MacLaren, G., & Ichiba, S. (2021). Expanding controlled donation after the circulatory determination of death: stronger emphasis on different cultural, religious and legal backgrounds is needed. Intensive Care Medicine, 47(6), 724-725.
    • Lorusso, R. (2021). First Myocardial Resting or First Myocardial Revascularization for Cardiogenic Shock After Acute Myocardial Infarction-Related Cardiac Arrest? Still a Hamlet Dilemma ...Now, With Some More Clues ...Critical Care Medicine, 49(6), 999-1002.
    • Ravaux, J. M., Di Mauro, M., Vernooy, K., Mariani, S., Ronco, D., Simons, J., Van't Hof, A. W., Veenstra, L., Kats, S., Maessen, J. G., & Lorusso, R. (2021). Impact of Bundle Branch Block on Permanent Pacemaker Implantation after Transcatheter Aortic Valve Implantation: A Meta-Analysis. Journal of Clinical Medicine, 10(12), [2719].
    • Martucci, G., Amata, M., di Francesco, F., Traina, M., Arcadipane, A., Lorusso, R., & Granata, A. (2021). Management of intra-abdominal hypertension during ECMO: Total water-assisted colonoscopy as a step-up minimally invasive treatment, and a literature review. Endoscopy international open, 09(06), E848-E852.
    • Di Mauro, M., Lorusso, R., Parolari, A., Ravaux, J. M., Bonalumi, G., Guarracini, S., Ricci, F., Benedetto, U., & Calafiore, A. M. (2021). The best approach for functional tricuspid regurgitation: A network meta-analysis. Journal of Cardiac Surgery, 36(6), 2072-2080.
    • Moscarelli, M., Lorusso, R., Abdullahi, Y., Varone, E., Marotta, M., Solinas, M., Casula, R., Parlanti, A., Speziale, G., Fattouch, K., & Athanasiou, T. (2021). The Effect of Minimally Invasive Surgery and Sternotomy on Physical Activity and Quality of Life. Heart Lung and Circulation, 30(6), 882-887.
    • Ronco, D., Matteucci, M., Ravaux, J. M., Marra, S., Torchio, F., Corazzari, C., Massimi, G., Beghi, C., Maessen, J., & Lorusso, R. (2021). Mechanical Circulatory Support as a Bridge to Definitive Treatment in Post-Infarction Ventricular Septal Rupture. Jacc-Cardiovascular Interventions, 14(10), 1053-1066.
    • Mang, S., Kalenka, A., Broman, L. M., Supady, A., Swol, J., Danziger, G., Becker, A., Horsch, S. I., Mertke, T., Kaiser, R., Bracht, H., Zotzmann, V., Seiler, F., Bals, R., Taccone, F. S., Moerer, O., Lorusso, R., Belohlavek, J., Muellenbach, R. M., ... COVEC-Study Group (2021). Extracorporeal life support in COVID-19-related acute respiratory distress syndrome: A EuroELSO international survey. Artificial Organs, 45(5), 495-505.
    • Matteucci, M., Ferrarese, S., Corazzari, C., Telli, G., Mantovani, V., Lorusso, R., & Beghi, C. (2021). Ascending aortic aneurysm repair in the setting of Tako-tsubo cardiomyopathy. Perfusion, 36(4), 429-431. [0267659120950206].
    • Willers, A., Swol, J., Kowalewski, M., Raffa, G. M., Meani, P., Jiritano, F., Matteucci, M., Fina, D., Heuts, S., Bidar, E., Natour, E., Sels, J. W., Delnoij, T., & Lorusso, R. (2021). Extracorporeal Life Support in Hemorrhagic Conditions: A Systematic Review. Asaio Journal, 67(5), 476-484.
    • Badulak, J., Antonini, M. V., Stead, C. M., Shekerdemian, L., Raman, L., Paden, M. L., Agerstrand, C., Bartlett, R. H., Barrett, N., Combes, A., Lorusso, R., Mueller, T., Ogino, M. T., Peek, G., Pellegrino, V., Rabie, A. A., Salazar, L., Schmidt, M., Shekar, K., ... ELSO COVID-19 Working Group Members (2021). Extracorporeal Membrane Oxygenation for COVID-19: Updated 2021 Guidelines from the Extracorporeal Life Support Organization. Asaio Journal, 67(5), 485-495.