Roberto Lorusso

Professor

Prof. Roberto Lorusso studied medicine at the University of Milan, Italy and graduated in 1987 magna cum Laude. He worked at Maastricht UMC+ in 1990 at CTC research and in 1996 and 1997 at the academic Hospital of Leuven. In 1998, he successfully obtained his PhD degree at Maastricht University (thesis titled 'Cardiac reinforcement and assistance by electrically stimulated skeletal muscle').

Currently, Prof. Roberto Lorusso is staff member at the Department of Cardiothoracic Surgery at Maastricht UMC+, Director of the Extracorporeal Life Support (ECLS) Program, Full Professor of Cardiac Surgery and ECLS at the Maastricht University and CARIM. His research group is focussed on mechanical circulatory support, minimally invasive valve surgery, coronary surgery, cardiac valve disease, extracorporeal circulation, acute myocardial infarction complications, cardiac valve disease, preclinical and clinical research.

Prof. Roberto Lorusso won the Gasperis-Donatelli Prize in 1989, a Young Investigator Award in 1995 and the Lillehei Award in 1998 by the European Association for Cardio-Thoracic Surgery.  He was Scientific Secretary of the Italian Society for Cardiac Surgery in 2007 and 2008, President of Euro-ELSO (2015-2017), and he is currently Editor-in-Chief of the Multi-Media Manual of Cardio-Thoracic Surgery as well as member of the ELSO Executive Committee.

He has almost 300 publications in PubMed, and has given more than 300 presentations at international meetings as invited speaker. He is Principal Investigator of international multicentre clinical studies and grant receiver from several funding bodies for clinical as well as pre-clinical investigations.

Department of Cardiothoracic surgery
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: D.2037
T: +31(0)43 387 60 32

  • 2020
    • Zakhary, B., Vercaemst, L., Mason, P., Antonini, M. V., Lorusso, R., & Brodie, D. (2020). How I approach membrane lung dysfunction in patients receiving ECMO. Critical Care, 24(1), [671]. https://doi.org/10.1186/s13054-020-03388-2
    • Wengenmayer, T., Muellenbach, R. M., Taccone, F. S., Kredel, M., Kalenka, A., Belohlavek, J., Spangenberg, T., Haake, H., Bracht, H., Moerer, O., Lorusso, R., & Lepper, P. M. (2020). Extracorporeal Membrane Oxygenation for Critically Ill Patients with COVID-19-related Acute Respiratory Distress Syndrome: Worth the Effort!American Journal of Respiratory and Critical Care Medicine, 202(10), 1477-1479. https://doi.org/10.1164/rccm.202006-2505LE
    • Swol, J., Shigemura, N., Ichiba, S., Steinseifer, U., Anraku, M., & Lorusso, R. (2020). Artificial lungs--Where are we going with the lung replacement therapy?Artificial Organs, 44(11), 1135-1149. https://doi.org/10.1111/aor.13801
    • D'Auria, F., Casado, A. P., Myat, A., Lorusso, R., & Hildick-Smith, D. (2020). Long-Term Survival and Outcomes According to VARC-2 Criteria for Subclavian, Direct Aortic, Femoral, and Apical Implantation: An 8-Year United Kingdom TAVI Surgical Experience. Surgical Technology International, 37, 245-252. https://pubmed.ncbi.nlm.nih.gov/32819023/
    • Broman, L. M., Westlund, C. J., Gilbers, M., da Camara, L. P., Wittberg, L. P., Taccone, F. S., Malfertheiner, M., Di Nardo, M., Swol, J., Vercaemst, L., Barrett, N. A., Pappalardo, F., Belohlavek, J., Belliato, M., & Lorusso, R. (2020). Pressure and flow properties of dual-lumen cannulae for extracorporeal membrane oxygenation. Perfusion, 35(8), 736-744. https://doi.org/10.1177/0267659120926009
    • Amata, M., Martucci, G., Granata, A., Tuzzolino, F., Panarello, G., Bianco, C., Lorusso, R., Traina, M., & Arcadipane, A. (2020). The role of endoscopy as non-invasive procedure to manage gastrointestinal complications during extracorporeal membrane oxygenation. Perfusion, 35(8), 786-794. https://doi.org/10.1177/0267659120909669
    • Brogan, T., Thiagarajan, R. R., Lorusso, R., McMullan, D. M., Di Nardo, M., Ogino, M. T., Dalton, H. J., Burke, C. R., & Capatos, G. (2020). The use of extracorporeal membrane oxygenation in human immunodeficiency virus-positive patients: a review of a multicenter database. Perfusion, 35(8), 772-777. https://doi.org/10.1177/0267659120906966
    • Di Mauro, M., Dato, G. A., Sponga, S., & Lorusso, R. (2020). Timing chirurgico nell’endocardite infettiva valvolare. Giornale Italiano di Cardiologia, 21(11), 890-895. https://doi.org/10.1714/3455.34443
    • Barbaro, R. P., MacLaren, G., Boonstra, P. S., Iwashyna, T. J., Slutsky, A. S., Fan, E., Bartlett, R. H., Tonna, J. E., Hyslop, R., Fanning, J. J., Rycus, P. T., Hyer, S. J., Anders, M. M., Agerstrand, C. L., Hryniewicz, K., Diaz, R., Lorusso, R., Combes, A., Brodie, D., & Extracorporeal Life Support Organization (2020). Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry. Lancet, 396(10257), 1071-1078. https://doi.org/10.1016/S0140-6736(20)32008-0
    • Mariani, S., Richter, J., Pappalardo, F., Belohlavek, J., Lorusso, R., Schmitto, J. D., Bauersachs, J., & Napp, L. C. (2020). Mechanical circulatory support for Takotsubo syndrome: a systematic review and meta-analysis. International Journal of Cardiology, 316, 31-39. https://doi.org/10.1016/j.ijcard.2020.05.033
    • Cho, S-M., Canner, J., Chiarini, G., Calligy, K., Caturegli, G., Rycus, P., Barbaro, R. P., Tonna, J., Lorusso, R., Kilic, A., Choi, C. W., Ziai, W., Geocadin, R., & Whitman, G. (2020). Modifiable Risk Factors and Mortality From Ischemic and Hemorrhagic Strokes in Patients Receiving Venoarterial Extracorporeal Membrane Oxygenation: Results From the Extracorporeal Life Support Organization Registry. Critical Care Medicine, 48(10), E897-E905. https://doi.org/10.1097/CCM.0000000000004498
    • Sponga, S., Di Mauro, M., Malvindi, P. G., Paparella, D., Murana, G., Pacini, D., Weltert, L., De Paulis, R., Cappabianca, G., Beghi, C., De Vincentiis, C., Parolari, A., Messina, A., Troise, G., Salsano, A., Santini, F., Pierri, M. D., Di Eusanio, M., Maselli, D., ... Italian Group of Research for Outcome in Cardiac Surgery (GIROC) (2020). Surgery for Bentall endocarditis: short- and midterm outcomes from a multicentre registry. European Journal of Cardio-Thoracic Surgery, 58(4), 839-846. https://doi.org/10.1093/ejcts/ezaa136
    • Swol, J., & Lorusso, R. (2020). Additive treatment considerations in COVID-19-The clinician's perspective on extracorporeal adjunctive purification techniques. Artificial Organs, 44(9), 918-925. https://doi.org/10.1111/aor.13748
    • Piacente, C., Martucci, G., Miceli, V., Pavone, G., Papeo, A., Occhipinti, G., Panarello, G., Lorusso, R., Tanaka, K., & Arcadipane, A. (2020). A narrative review of antithrombin use during veno-venous extracorporeal membrane oxygenation in adults: rationale, current use, effects on anticoagulation, and outcomes. Perfusion, 35(6), 452-464. https://doi.org/10.1177/0267659120913803
    • Fina, D., Matteucci, M., Jiritano, F., Meani, P., Lo Coco, V., Kowalewski, M., Maessen, J., Guazzi, M., Ballotta, A., Ranucci, M., & Lorusso, R. (2020). Extracorporeal membrane oxygenation without therapeutic anticoagulation in adults: A systematic review of the current literature. International Journal of Artificial Organs, 43(9), 570-578. https://doi.org/10.1177/0391398820904372
    • Kowalewski, M., Gozdek, M., Zielinski, K., Raffa, G. M., Suwalski, P., & Lorusso, R. (2020). Long-term mortality after percutaneous coronary intervention with drug-eluting stents compared with coronary artery bypass grafting for multivessel and left main disease: a meta-analysis. Kardiologia Polska, 78(7-8), 759-761. https://doi.org/10.33963/KP.15397
    • Abrams, D., Lorusso, R., Vincent, J-L., & Brodie, D. (2020). ECMO during the COVID-19 pandemic: when is it unjustified?Critical Care, 24(1), [507]. https://doi.org/10.1186/s13054-020-03230-9
    • Jiritano, F., Lorusso, R., & Santarpino, G. (2020). Causes of Thrombocytopenia in Cardiac Surgery: Looking for the Holy Grail?Annals of Thoracic Surgery, 110(2), 751-752. https://doi.org/10.1016/j.athoracsur.2020.01.018
    • Ong, J., Zhang, J. J. Y., Lorusso, R., MacLaren, G., & Ramanathan, K. (2020). Extracorporeal membrane oxygenation in pregnancy and the postpartum period: a systematic review of case reports. International Journal of Obstetric Anesthesia, 43, 106-113. https://doi.org/10.1016/j.ijoa.2020.04.004
    • Calafiore, A. M., Lorusso, R., Kheirallah, H., Alsaied, M. M., Alfonso, J. J. R. A., Di Baldassare, A., Gallina, S., Gaudino, M., & Di Mauro, M. (2020). Late tricuspid regurgitation and right ventricular remodeling after tricuspid annuloplasty. Journal of Cardiac Surgery, 35(8), 1891-1900. https://doi.org/10.1111/jocs.14840
    • Worku, E., Gill, D., Brodie, D., Lorusso, R., Combes, A., & Shekar, K. (2020). Provision of ECPR during COVID-19: evidence, equity, and ethical dilemmas. Critical Care, 24(1), [462]. https://doi.org/10.1186/s13054-020-03172-2
    • Olson, T. L., O'Neil, E. R., Ramanathan, K., Lorusso, R., MacLaren, G., & Anders, M. M. (2020). Extracorporeal membrane oxygenation in peripartum cardiomyopathy: A review of the ELSO Registry. International Journal of Cardiology, 311, 71-76. https://doi.org/10.1016/j.ijcard.2020.03.006
    • Mariani, S., Napp, L. C., Lo Coco, V., Delnoij, T. S. R., Luermans, J. G. L. M., ter Bekke, R. M. A., Timmermans, C., Li, T., Dogan, G., Schmitto, J. D., Maessen, J., Maesen, B., & Lorusso, R. (2020). Mechanical circulatory support for life -threatening arrhythmia: A systematic review. International Journal of Cardiology, 308, 42-49. https://doi.org/10.1016/j.ijcard.2020.03.045
    • ESC Scientific Document Group (2020). Comentarios a la guía ESC 2019 sobre embolia pulmonar aguda. Revista Espanola de Cardiologia, 73(6), 452-456. https://doi.org/10.1016/j.recesp.2019.12.030
    • Lorusso, R., Miceli, A., Gelsomino, S., Lio, A., Parise, O., Montisci, A., Vizzardi, E., Pacini, D., Di Bartolomeo, R., Renzulli, A., Serraino, F. G., Comoglio, C., Liberi, R., Martinelli, G., Sciangula, A., Mazzola, A., Faragalli, F., De Bonis, M., Taramasso, M., ... Glauber, M. (2020). Mitral Valve Replacement with a Third Generation Porcine Valve: an Italian Multicentered Study. Annals of Thoracic Surgery, 109(6), 1865-1872. https://doi.org/10.1016/j.athoracsur.2019.08.111
    • Jiritano, F., Serraino, G. F., ten Cate, H., Fina, D., Matteucci, M., Mastroroberto, P., & Lorusso, R. (2020). Platelets and extra-corporeal membrane oxygenation in adult patients: a systematic review and meta-analysis. Intensive Care Medicine, 46(6), 1154-1169. https://doi.org/10.1007/s00134-020-06031-4
    • Kowalewski, M., Fina, D., Stomka, A., Raffa, G. M., Martucci, G., Lo Coco, V., De Piero, M. E., Ranucci, M., Suwalski, P., & Lorusso, R. (2020). COVID-19 and ECMO: the interplay between coagulation and inflammation-a narrative review. Critical Care, 24(1), [205]. https://doi.org/10.1186/s13054-020-02925-3
    • Swol, J., Lorusso, R., Di Nardo, M., Vercaemst, L., Finney, S. J., Jones, T. J., Barrett, N. A., & Belohlavek, J. (2020). ECLS Training and Simulation - Evaluation of the 8th Educational Corner of the EuroELSO Congress 2019 Held in Barcelona. Perfusion, 35, 86-92. https://doi.org/10.1177/0267659120909001
    • Matteucci, M., Kowalewski, M., Fina, D., Jiritano, F., Meani, P., Raffa, G. M., Aldobayyan, I., Beghi, C., Maessen, J., & Lorusso, R. (2020). Extracorporeal life support for phaeochromocytoma-induced cardiogenic shock: a systematic review. Perfusion, 35, 20-28. https://doi.org/10.1177/0267659120908413
    • Ramanathan, K., Tan Chuen Seng, Rycus, P., Anders, M., Lorusso, R., Zhang, J. J. Y., & MacLaren, G. (2020). Extracorporeal Membrane Oxygenation in Pregnancy: An Analysis of the Extracorporeal Life Support Organization Registry. Critical Care Medicine, 48(5), 696-703. https://doi.org/10.1097/CCM.0000000000004269
    • Fina, D., Matteucci, M., Jiritano, F., Meani, P., Kowalewski, M., Ballotta, A., Ranucci, M., & Lorusso, R. (2020). Extracorporeal membrane oxygenation without systemic anticoagulation: a case-series in challenging conditions. Journal of Thoracic Disease, 12(5), 2113-2119. https://doi.org/10.21037/jtd.2020.04.54
    • Malfertheiner, M. V., Broman, L. M., Vercaemst, L., Belliato, M., Aliberti, A., Di Nardo, M., Swol, J., Barrett, N., Pappalardo, F., Belohlavek, J., Taccone, F. S., Millar, J. E., Crawford, L., Lorusso, R., Suen, J. Y., & Fraser, J. F. (2020). Ex vivo models for research in extracorporeal membrane oxygenation: a systematic review of the literature. Perfusion, 35, 38-49. https://doi.org/10.1177/0267659120907439
    • Bartlett, R. H., Ogino, M. T., Brodie, D., McMullan, D. M., Lorusso, R., MacLaren, G., Stead, C. M., Rycus, P., Fraser, J. F., Belohlavek, J., Salazar, L., Mehta, Y., Raman, L., & Paden, M. L. (2020). Initial ELSO Guidance Document: ECMO for COVID-19 Patients with Severe Cardiopulmonary Failure. Asaio Journal, 66(5), 472-474. https://doi.org/10.1097/MAT.0000000000001173
    • Lepper, P. M., Barrett, N. A., Swol, J., Lorusso, R., Di Nardo, M., Belliato, M., Belohlavek, J., & Broman, L. M. (2020). Perception of prolonged extracorporeal membrane oxygenation in Europe: an EuroELSO survey. Perfusion, 35(1SI), 81-85. https://doi.org/10.1177/0267659120909740
    • Lorusso, R., & Belohlavek, J. (2020). Supporting the circulation, but injuring the brain: the (still unsolved) threat and paradox of extracorporeal life support. Perfusion, 35, 5-7. https://doi.org/10.1177/0267659120909080
    • Zakhary, B., Vercaemst, L., Mason, P., Lorusso, R., & Brodie, D. (2020). How I manage drainage insufficiency on extracorporeal membrane oxygenation. Critical Care, 24(1), [151]. https://doi.org/10.1186/s13054-020-02870-1
    • Kowalewski, M., Raffa, G., Zielinski, K., Meani, P., Alanazi, M., Gilbers, M., Heuts, S., Natour, E., Bidar, E., Schreurs, R., Delnoij, T., Driessen, R., Sels, J. W., van de Poll, M., Roekaerts, P., Maessen, J., Suwalski, P., & Lorusso, R. (2020). Baseline surgical status and short-term mortality after extracorporeal membrane oxygenation for post-cardiotomy shock: a meta-analysis. Perfusion, 35(3), 246-254. https://doi.org/10.1177/0267659119865122
    • Kowalewski, M., Malvindi, P. G., Zielinski, K., Martucci, G., Slomka, A., Suwalski, P., Lorusso, R., Meani, P., Arcadipane, A., Pilato, M., & Raffa, G. M. (2020). Left Ventricle Unloading with Veno-Arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock. Systematic Review and Meta-Analysis. Journal of Clinical Medicine, 9(4), [1039]. https://doi.org/10.3390/jcm9041039
    • Lorusso, R. (2020). Education and Training in Extracorporeal Life Support: The Structured, Visionary, and Needed Mission of the Extracorporeal Life Support Organization ... Not Forgetting Problem-Based Learning, Ethics, and Leadership. Critical Care Medicine, 48(3), 435-437. https://doi.org/10.1097/CCM.0000000000004196
    • Gozdek, M., Ratajczak, J., Arndt, A., Zielinski, K., Pasierski, M., Matteucci, M., Fina, D., Jiritano, F., Meani, P., Raffa, G. M., Malvindi, P. G., Pilato, M., Paparella, D., Slomka, A., Landes, U., Kornowski, R., Kubica, J., Lorusso, R., Suwalski, P., ... Thoracic Research Centre (2020). Transcatheter aortic valve replacement with Lotus and Sapien 3 prosthetic valves: a systematic review and meta-analysis. Journal of Thoracic Disease, 12(3), 893-906. https://doi.org/10.21037/jtd.2019.12.107
    • Lorusso, R., & Corradi, D. (2020). What you do not know, you do not recognize ... and you do not improve future patient care ... particularly in extracorporeal life support (ECLS) patients (vol 11, pg S1930, 2019). Journal of Thoracic Disease, 12(3), 1157-1157. https://doi.org/10.21037/jtd.2019.11.39
    • Konstantinides, S., Meyer, G., Becattini, C., Bueno, H., Geersing, G-J., Harjola, V-P., Huisman, M., Humbert, M., Jennings, C. S., Jimenez, D., Kucher, N., Lang, I. M., Lankeit, M., Lorusso, R., Mazzolai, L., Meneveau, N., Ainle, F. N., Prandoni, P., Pruszczyk, P., ... Luis Zamorano, J. (2020). 2019 ESC Guidelines for the dignosis and management of acute pulmonary embolism development Toed in colaboration with the European Respiratory Society (ERS). European Heart Journal, 41(4), 543-603. https://doi.org/10.1093/eurheartj/ehz405
    • Kowalewski, M., Raffa, G. M., Zielinski, K., Alanazi, M., Gilbers, M., Heuts, S., Natour, E., Bidar, E., Schreurs, R., Delnoij, T., Driessen, R., Sels, J-W., van de Poll, M., Roekaerts, P., Meani, P., Maessen, J., Suwalski, P., & Lorusso, R. (2020). The impact of Centre's heart transplant status and volume on in-hospital outcomes following extracorporeal membrane oxygenation for refractory post-cardiotomy cardiogenic shock: a meta-analysis. BMC Cardiovascular disorders, 20(1), [10]. https://doi.org/10.1186/s12872-019-01317-y
    • De Piero, M. E., Lo Coco, V., Taccone, F. S., Belliato, M., Broman, L. M., Malfertheiner, M. V., & Lorusso, R. (2020). Has Venoarterial ECMO Been Underutilized in COVID-19 Patients?Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, 15(4), 317-321. https://doi.org/10.1177/1556984520939076
  • 2019
    • Lorusso, R., Moscarelli, M., Di Franco, A., Grazioli, V., Nicolini, F., Gherli, T., De Bonis, M., Taramasso, M., Villa, E., Troise, G., Scrofani, R., Antona, C., Mariscalco, G., Beghi, C., Miceli, A., Glauber, M., Ranucci, M., De Vincentiis, C., & Gaudino, M. (2019). Association Between Coronary Artery Bypass Surgical Techniques and Postoperative Stroke. Journal of the American Heart Association, 8(24), [013650]. https://doi.org/10.1161/JAHA.119.013650
    • Jiritano, F., Santarpino, G., Serraino, G. F., Ten Cate, H., Matteucci, M., Fina, D., Mastroroberto, P., & Lorusso, R. (2019). Peri-procedural thrombocytopenia after aortic bioprosthesis implant: A systematic review and meta-analysis comparison among conventional, stentless, rapid-deployment, and transcatheter valves. International Journal of Cardiology, 296, 43-50. https://doi.org/10.1016/j.ijcard.2019.07.056
    • Matteucci, M., Fina, D., Jiritano, F., Blankesteijn, W. M., Raffa, G. M., Kowalewski, M., Beghi, C., & Lorusso, R. (2019). Corrigendum to: Sutured and sutureless repair of postinfarction left ventricular free-wall rupture: a systematic review (vol 56, pg 840, 2019). European Journal of Cardio-Thoracic Surgery, 56(5), 1023-1023. https://doi.org/10.1093/ejcts/ezz150
    • Lorusso, R., Raffa, G. M., Kowalewski, M., Alenizy, K., Sluijpers, N., Makhoul, M., Brodie, D., McMullan, M., Wang, I-W., Meani, P., MacLaren, G., Dalton, H., Barbaro, R., Hou, X., Cavarocchi, N., Chen, Y-S., Thiagarajan, R., Alexander, P., Alsoufi, B., ... Whitman, G. (2019). Structured review of post-cardiotomy extracorporeal membrane oxygenation: Part 2-pediatric patients. Journal of Heart and Lung Transplantation, 38(11), 1144-1161. https://doi.org/10.1016/j.healun.2019.07.004
    • Lorusso, R., Raffa, G. M., Alenizy, K., Sluijpers, N., Makhoul, M., Brodie, D., McMullan, M., Wang, I-W., Meani, P., MacLaren, G., Kowalewski, M., Dalton, H., Barbaro, R., Hou, X., Cavarocchi, N., Chen, Y-S., Thiagarajan, R., Alexander, P., Alsoufi, B., ... Whitman, G. J. R. (2019). Structured review of post-cardiotomy extracorporeal membrane oxygenation: part 1-Adult patients. Journal of Heart and Lung Transplantation, 38(11), 1125-1143. https://doi.org/10.1016/j.healun.2019.08.014
    • Matteucci, M., Fina, D., Jiritano, F., Blankesteijn, W. M., Raffa, G. M., Kowalewski, M., Beghi, C., & Lorusso, R. (2019). Sutured and sutureless repair of postinfarction left ventricular free-wall rupture: a systematic review. European Journal of Cardio-Thoracic Surgery, 56(5), 840-848. https://doi.org/10.1093/ejcts/ezz101