Publications
- 2022
- Top, W. M. C., Lehert, P., Schalkwijk, C. G., Stehouwer, C. D. A., & Kooy, A. (2022). Effect of metformin on arginine and dimethylarginines in patients with advanced type 2 diabetes: A post hoc analysis of a randomized trial. Diabetes Obesity & Metabolism, 24(10), 1983-1988. https://doi.org/10.1111/dom.14784
- Janssen, L. E. F., Simons, N., Simons, P. I. H. G., Schaper, N. C., Feskens, E. J. M., van der Ploeg, L. M. C., Van den Eynde, M. D. G., Schalkwijk, C. G., Houben, A. J. H. M., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Effects of fructose restriction on blood pressure: Secondary analysis of a double-blind randomized controlled trial. Clinical Nutrition ESPEN, 51, 97-103. https://doi.org/10.1016/j.clnesp.2022.07.009
- Brouwers, M. C. G. J. (2022). Fructose 1-phosphate, an evolutionary signaling molecule of abundancy. Trends in Endocrinology and Metabolism, 33(10), 680-689. https://doi.org/10.1016/j.tem.2022.07.007
- Verhulst, C. E. M., Fabricius, T. W., Teerenstra, S., Kristensen, P. L., Tack, C. J., McCrimmon, R. J., Heller, S., Evans, M. L., Amiel, S. A., Pedersen-Bjergaard, U., de Galan, B. E., & Hypo-RESOLVE Consortium (2022). Glycaemic thresholds for counterregulatory hormone and symptom responses to hypoglycaemia in people with and without type 1 diabetes: a systematic review. Diabetologia, 65(10), 1601-1612. https://doi.org/10.1007/s00125-022-05749-8
- Sun, C., van Soest, J., Koster, A., Eussen, S. J. P. M., Schram, M. T., Stehouwer, C. D. A., Dagnelie, P. C., & Dumontier, M. (2022). Studying the association of diabetes and healthcare cost on distributed data from the Maastricht Study and Statistics Netherlands using a privacy-preserving federated learning infrastructure. Journal of Biomedical Informatics, 134, Article 104194. https://doi.org/10.1016/j.jbi.2022.104194
- Geraets, A. F. J., Schram, M. T., Jansen, J. F. A., Backes, W. H., Schalkwijk, C. G., Stehouwer, C. D. A., van Boxtel, M. P. J., Eussen, S. J. P. M., Kooman, J. P., Verhey, F. R. J., & Köhler, S. (2022). The cardiometabolic depression subtype and its association with clinical characteristics: The Maastricht Study. Journal of Affective Disorders, 313, 110-117. https://doi.org/10.1016/j.jad.2022.06.045
- Gulikers, J. L., Slikkerveer, M., Winckers, K., Hendriks, L. E. L., Dursun, S., Croes, S., & van Geel, R. M. J. M. (2022). Case report: Drug-drug interaction between alectinib and apixaban in NSCLC. Current Problems in Cancer: Case Reports, 7, Article 100186. https://doi.org/10.1016/j.cpccr.2022.100186
- van Veelen, A., Gulikers, J., Hendriks, L. E. L., Dursun, S., Ippel, J., Smit, E. F., Dingemans, A. M. C., van Geel, R., & Croes, S. (2022). Pharmacokinetic boosting of osimertinib with cobicistat in patients with non-small cell lung cancer: The OSIBOOST trial. Lung Cancer, 171, 97-102. https://doi.org/10.1016/j.lungcan.2022.07.012
- Verhulst, C. E. M., Fabricius, T. W., Nefs, G., Kessels, R. P. C., Pouwer, F., Teerenstra, S., Tack, C. J., Broadley, M. M., Kristensen, P. L., McCrimmon, R. J., Heller, S., Evans, M. L., Pedersen-Bjergaard, U., & de Galan, B. E. (2022). Consistent Effects of Hypoglycemia on Cognitive Function in People With or Without Diabetes. Diabetes Care, 45(9), 2103-2110. https://doi.org/10.2337/dc21-2502
- Koeneman, M., Olde Bekkink, M., Meijel, L. V., Bredie, S., & de Galan, B. (2022). Effect of Hypoglycemia on Heart Rate Variability in People with Type 1 Diabetes and Impaired Awareness of Hypoglycemia. DST Journal of Diabetes Science and Technology, 16(5), 1144-1149. https://doi.org/10.1177/19322968211007485
- Divilly, P., Zaremba, N., Mahmoudi, Z., Søholm, U., Pollard, D. J., Broadley, M., Abbink, E. J., de Galan, B., Pedersen-Bjergaard, U., Renard, E., Evans, M., Speight, J., Brennan, A., McCrimmon, R. J., Müllenborn, M., Heller, S., Seibold, A., Mader, J. K., Amiel, S. A., ... Hypo-RESOLVE Consortium (2022). Hypo-METRICS: Hypoglycaemia - MEasurement, ThResholds and ImpaCtS - A multi-country clinical study to define the optimal threshold and duration of sensor-detected hypoglycaemia that impact the experience of hypoglycaemia, quality of life and health economic outcomes: the study protocol. Diabetic Medicine, 39(9), Article e14892. https://doi.org/10.1111/dme.14892
- Baylan, U., Korn, A., Emmens, R. W., Schalkwijk, C. G., Niessen, H. W. M., Krijnen, P. A. J., & Simsek, S. (2022). Liraglutide treatment attenuates inflammation markers in the cardiac, cerebral and renal microvasculature in streptozotocin-induced diabetic rats. European Journal of Clinical Investigation, 52(9), Article e13807. https://doi.org/10.1111/eci.13807
- van Vliet, K., van Ginkel, W. G., Jahja, R., Daly, A., MacDonald, A., Santra, S., De Laet, C., Goyens, P. J., Vara, R., Rahman, Y., Cassiman, D., Eyskens, F., Timmer, C., Mumford, N., Gissen, P., Bierau, J., van Hasselt, P. M., Wilcox, G., Morris, A. A. M., ... van Spronsen, F. J. (2022). Neurocognitive outcome and mental health in children with tyrosinemia type 1 and phenylketonuria: A comparison between two genetic disorders affecting the same metabolic pathway. Journal of Inherited Metabolic Disease, 45(5), 952-962. https://doi.org/10.1002/jimd.12528
- Koene, E., Schrauwen-Hinderling, V. B., Schrauwen, P., & Brouwers, M. C. G. J. (2022). Novel insights in intestinal and hepatic fructose metabolism: from mice to men. Current Opinion in Clinical Nutrition and Metabolic Care, 25(5), 354-359. https://doi.org/10.1097/MCO.0000000000000853
- van Dinther, M., Voorter, P. H. M., Schram, M. T., Berendschot, T. T. J. M., Houben, A. J. H. M., Webers, C. A. B., van Oostenbrugge, R. J., Backes, W. H., Staals, J., & Jansen, J. F. A. (2022). Retinal microvascular function is associated with the cerebral microcirculation as determined by intravoxel incoherent motion MRI. Journal of the Neurological Sciences, 440, Article 120359. https://doi.org/10.1016/j.jns.2022.120359
- Leung, S. S., Borg, D. J., McCarthy, D. A., Boursalian, T. E., Cracraft, J., Zhuang, A., Fotheringham, A. K., Flemming, N., Watkins, T., Miles, J. J., Groop, P.-H., Scheijen, J. L., Schalkwijk, C. G., Steptoe, R. J., Radford, K. J., Knip, M., & Forbes, J. M. (2022). Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells. Diabetes, 71(9), 1994-2008. https://doi.org/10.2337/db22-0177
- Goossens, P., Lu, C., Cao, J., Gijbels, M. J., Karel, J. M. H., Wijnands, E., Claes, B. S. R., Fazzi, G. E., Hendriks, T. F. E., Wouters, K., Smirnov, E., van Zandvoort, M. J. M., Balluff, B., Cuypers, E., Donners, M. M. P. C., Heeren, R. M. A., & Biessen, E. A. L. (2022). Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context. Cell Metabolism, 34(8), 1214-1225.e6. https://doi.org/10.1016/j.cmet.2022.06.012
- Zhang, X., Schalkwijk, C. G., & Wouters, K. (2022). Immunometabolism and the modulation of immune responses and host defense: A role for methylglyoxal?Biochimica et Biophysica Acta-Molecular Basis of Disease, 1868(8), Article 166425. https://doi.org/10.1016/j.bbadis.2022.166425
- Latten, G., Claassen, L., Muris, J., Cals, J., & Stassen, P. (2022). Koorts op de HAP: vitals, beslisregels en niet-pluisgevoel. Huisarts en Wetenschap, 65(8), 21-25. https://doi.org/10.1007/s12445-022-1507-x
- Barutta, F., Bellini, S., Guarrera, S., Matullo, G., Schalkwijk, C., Stehouwer, C. D., Chaturvedi, N., Soedamah-Muthu, S. S., Durazzo, M., & Gruden, G. (2022). Association of Serum MicroRNA-145-5p Levels with Microvascular Complications of Type 1 Diabetes: the EURODIAB Prospective Complications Study. Diabetes Research and Clinical Practice, 190, Article 109987. https://doi.org/10.1016/j.diabres.2022.109987
- Haring, M. P. D., Peeks, F., Oosterveer, M. H., Brouwers, M. C. G. J., Hollak, C. E. M., Janssen, M. C. H., Langendonk, J. G., Rennings, A. J. M., Wagenmakers, M. A. E. M., Verkade, H. J., Derks, T. G. J., & de Meijer, V. E. (2022). High childhood serum triglyceride concentrations associate with hepatocellular adenoma development in patients with glycogen storage disease type Ia. JHEP Reports, 4(8), Article 100512. https://doi.org/10.1016/j.jhepr.2022.100512
- Brouwers, M. C. G. J., Simons, N., Kooi, M. E., de Ritter, R., van Dongen, M. C. J. M., Eussen, S. J. P. M., Bekers, O., Kooman, J., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schram, M. T., Schaper, N. C., Schalkwijk, C. G., & Stehouwer, C. D. A. (2022). Intrahepatic lipid content is independently associated with soluble E-selectin levels: The Maastricht study. Digestive and Liver Disease, 54(8), 1038-1043. https://doi.org/10.1016/j.dld.2022.01.130
- Wauben, B., van Yperen, N. C., van der Poel, M. W., Köhler, S., van Greevenbroek, M. M., & Schouten, H. C. (2022). Long-term effects after stem cell transplantation identified: design of the MOSA study. Journal of Clinical Epidemiology, 148, 10-16. https://doi.org/10.1016/j.jclinepi.2022.03.012
- Broadley, M., Chatwin, H., Søholm, U., Amiel, S. A., Carlton, J., De Galan, B. E., Hendrieckx, C., McCrimmon, R. J., Skovlund, S. E., Pouwer, F., Speight, J., & Hypo-RESOLVE Consortium (2022). The 12-Item Hypoglycemia Impact Profile (HIP12): psychometric validation of a brief measure of the impact of hypoglycemia on quality of life among adults with type 1 or type 2 diabetes. BMJ Open Diabetes Research & Care, 10(4), Article e002890. https://doi.org/10.1136/bmjdrc-2022-002890
- van Dalem, J., Werkman, N. C. C., van den Bergh, J. P., Rossi, B., Viggers, R., Eastell, R., Burden, A. M., Stehouwer, C. D. A., Klungel, O. H., Brouwers, M. C. G. J., & Driessen, J. H. M. (2022). Use of sodium-glucose co-transporter 2 inhibitors, changes in body mass index and risk of fracture: a population-based cohort study. Diabetes Research and Clinical Practice, 190, Article 109993. https://doi.org/10.1016/j.diabres.2022.109993
- Clemmensen, K. K. B., Koster, A., Nielen, J. T. H., Dagnelie, P. C., Stehouwer, C. D. A., Bosma, H., Wesselius, A., Færch, K., & Eussen, S. J. P. M. (2022). Role of weekday variation on glucose, insulin, and triglyceride: A cross-sectional analysis from The Maastricht Study. Journal of Clinical Endocrinology & Metabolism, 107(8), E3145-E3151. https://doi.org/10.1210/clinem/dgac286
- Rebelos, E., Daniele, G., Campi, B., Saba, A., Koskensalo, K., Ihalainen, J., Saukko, E., Nuutila, P., Backes, W. H., Jansen, J. F. A., Dagnelie, P. C., Köhler, S., de Galan, B. E., van Sloten, T. T., Stehouwer, C. D. A., & Ferrannini, E. (2022). Circulating N-Acetylaspartate does not track brain NAA concentrations, cognitive function or features of small vessel disease in humans. Scientific Reports, 12(1), Article 11530. https://doi.org/10.1038/s41598-022-15670-0
- Vranken, L., Wyers, C. E., Van der Velde, R. Y., Janzing, H. M. J., Kaarsemakers, S., Driessen, J., Eisman, J., Center, J. R., Nguyen, T. V., Tran, T., Bliuc, D., Geusens, P., & van den Bergh, J. P. (2022). Association between incident falls and subsequent fractures in patients attending the fracture liaison service after an index fracture: a 3-year prospective observational cohort study. BMJ Open, 12(7), Article e058983. https://doi.org/10.1136/bmjopen-2021-058983
- Dimakakos, E., Gomatou, G., Catalano, M., Olinic, D. M., Spyropoulos, A. C., Falanga, A., Maraveyas, A., Liew, A., Schulman, S., Belch, J., Gerotziafas, G., Marschang, P., Cosmi, B., Spaak, J., Syrigos, K., Antic, D., Blinc, A., Boc, V., Boccardo, F., ... CANCER-COVID-19 THROMBOSIS COLLABORATIVE GROUP (2022). Thromboembolic Disease in Patients With Cancer and COVID-19: Risk Factors, Prevention and Practical Thromboprophylaxis Recommendations–State-of-the-Art. Anticancer Research, 42(7), 3261-3274. Article 15815. https://doi.org/10.21873/anticanres.15815
- Jin, S., Kusters, Y. H. A. M., Houben, A. J. H. M., Plat, J., Joris, P. J., Mensink, R. P., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2022). A randomized diet-induced weight-loss intervention reduces plasma complement C3: Possible implication for endothelial dysfunction. Obesity, 30(7), 1401-1410. https://doi.org/10.1002/oby.23467
- Abtahi, S., Cordtz, R., Dreyer, L., Driessen, J. H. M., Boonen, A., & Burden, A. M. (2022). Biological disease-modifying antirheumatic drugs and osteoporotic fracture risk in patients with rheumatoid arthritis: a Danish cohort study. American Journal of Medicine, 135(7), 879-888.e3. https://doi.org/10.1016/j.amjmed.2022.01.017
- Stassen, P., & Westerman, D. (2022). Novice Doctors in the Emergency Department: A Scoping Review. Cureus Journal of Medical Science, 14(6), Article e26245. https://doi.org/10.7759/cureus.26245
- van Veelen, A., Abtahi, S., Souverein, P., Driessen, J. H. M., Klungel, O. H., Dingemans, A.-M. C., van Geel, R., de Vries, F., & Croes, S. (2022). Characteristics of patients with lung cancer in clinical practice and their potential eligibility for clinical trials evaluating tyrosine kinase inhibitors or immune checkpoint inhibitors. Cancer Epidemiology, 78, Article 102149. https://doi.org/10.1016/j.canep.2022.102149
- van Gemert, L. A., de Galan, B. E., Wevers, R. A., ter Heine, R., & Willemsen, M. A. (2022). Lactate infusion as therapeutical intervention: a scoping review. European Journal of Pediatrics, 181(6), 2227-2235. https://doi.org/10.1007/s00431-022-04446-3
- Sharma, S., Katz, R., Ginsberg, C., Bullen, A., Vallon, V., Thomson, S., Moe, O. W., Hoofnagle, A. N., de Leeuw, P. W., Kroon, A. A., Houben, A. J. H. M., & Ix, J. H. (2022). Renal Clearance of Fibroblast Growth Factor-23 (FGF23) and its Fragments in Humans. Journal of Bone and Mineral Research, 37(6), 1170-1178. https://doi.org/10.1002/jbmr.4553
- Simons, P. I. H. G., Valkenburg, O., Telgenkamp, I., van der Waaij, K. M., de Groot, D. M., Veeraiah, P., Bons, J. A. P., Derks, T. G. J., Schalkwijk, C. G., Schrauwen-Hinderling, V. B., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Serum sex hormone-binding globulin levels are reduced and inversely associated with intrahepatic lipid content and saturated fatty acid fraction in adult patients with glycogen storage disease type 1a. Journal of Endocrinological Investigation, 45(6), 1227-1234. https://doi.org/10.1007/s40618-022-01753-2
- Doola, R., Deane, A. M., Barrett, H. L., Okano, S., Tolcher, D. M., Gregory, K., Coombes, J. S., Schalkwijk, C., Todd, A. S., Forbes, J. M., & Sturgess, D. J. (2022). The impact of a modified carbohydrate formula, and its constituents, on glycaemic control and inflammatory markers: A nested mechanistic sub-study. Journal of Human Nutrition and Dietetics, 35(3), 455-465. https://doi.org/10.1111/jhn.12959
- Wautrecht, J.-C., Olinic, D.-M., Catalano, M., Baines, C., Belch, J., Blinc, A., Buschmann, I., Celovska, D., Colgan, M.-P., Dimakakos, E., Heiss, C., Kolossvary, E., Kozak, M., Kroon, B., Mazzolai, L., Marakomichelakis, G., Pecsvarady, Z., Pias Canedo, M. A., Quere, I., ... Willfort-Ehringer, A. (2022). UEMS Training Requirements for Angiology/Vascular Medicine: European Standards of Postgraduate Medica 2 Specialist Training (2022 Updated Version). International Angiology, 41(3), 258-274. https://doi.org/10.23736/S0392-9590.22.04893-3
- Ali, N., El Hamdaoui, S., Nefs, G., Tack, C. J., & De Galan, B. E. (2022). Improved glucometrics in people with type 1 diabetes 1 year into the COVID-19 pandemic. BMJ Open Diabetes Research & Care, 10(3), Article 002789. https://doi.org/10.1136/bmjdrc-2022-002789
- Linkens, A. M. A., van Best, N., Niessen, P. M., Wijckmans, N. E. G., de Goei, E. E. C., Scheijen, J. L. J. M., van Dongen, M. C. J. M., van Gool, C. C. J. A. W., de Vos, W. M., Houben, A. J. H. M., Stehouwer, C. D. A., Eussen, S. J. M. P., Penders, J., & Schalkwijk, C. G. (2022). A 4-Week Diet Low or High in Advanced Glycation Endproducts Has Limited Impact on Gut Microbial Composition in Abdominally Obese Individuals: The deAGEing Trial. International journal of molecular sciences, 23(10), Article 5328. https://doi.org/10.3390/ijms23105328
- Veugen, M. G. J., Onete, V. G., Henry, R. M. A., Brunner-La Rocca, H.-P., Koster, A., Dagnelie, P. C., Schaper, N. C., Sep, S. J. S., van der Kallen, C. J. H., van Boxtel, M. P. J., Reesink, K. D., Schouten, J. S., Savelberg, H. H. C. M., Köhler, S., Verhey, F. R., van den Bergh, J. P. W., Schram, M. T., & Stehouwer, C. D. A. (2022). Health burden in type 2 diabetes and prediabetes in The Maastricht Study. Scientific Reports, 12(1), 1-11. Article 7337. https://doi.org/10.1038/s41598-022-11136-5
- van Sloten, T. T., Souverein, P. C., Stehouwer, C. DA., & Driessen, J. H. (2022). Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers and risk of depression among older people with hypertension. Journal of Psychopharmacology, 36(5), 594-603. Article 02698811221082470. https://doi.org/10.1177/02698811221082470
- Buziau, A. M., Eussen, S. J. P. M., Kooi, M. E., van der Kallen, C. J. H., van Dongen, M. C. J. M., Schaper, N. C., Henry, R. M. A., Schram, M. T., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Bekers, O., Meex, S. J. R., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Fructose Intake From Fruit Juice and Sugar-Sweetened Beverages Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study. Diabetes Care, 45(5), 1116-1123. https://doi.org/10.2337/dc21-2123
- Vandercappellen, E. J., Koster, A., Savelberg, H. H. C. M., Eussen, S. J. P. M., Dagnelie, P. C., Schaper, N. C., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Kroon, A. A., Henry, R. M. A., & Stehouwer, C. D. A. (2022). Sedentary behaviour and physical activity are associated with biomarkers of endothelial dysfunction and low-grade inflammation-relevance for (pre)diabetes: The Maastricht Study. Diabetologia, 65(5), 777-789. https://doi.org/10.1007/s00125-022-05651-3
- Jensen, M. V., Broadley, M., Speight, J., Chatwin, H., Scope, A., Cantrell, A., Heller, S., de Galan, B. E., Hendrieckx, C., Pouwer, F., & Hypo-RESOLVE Consortium (2022). The impact of hypoglycaemia in children and adolescents with type 1 diabetes on parental quality of life and related outcomes: A systematic review. Pediatric Diabetes, 23(3), 390-405. https://doi.org/10.1111/pedi.13308
- Abtahi, S., Driessen, J. H. M., Burden, A. M., Souverein, P. C., van den Bergh, J. P., van Staa, T. P., Boonen, A., & de Vries, F. (2022). Low-dose oral glucocorticoid therapy and risk of osteoporotic fractures in patients with rheumatoid arthritis: a cohort study using the Clinical Practice Research Datalink. Rheumatology, 61(4), 1448-1458. https://doi.org/10.1093/rheumatology/keab548
- Odintsova, V. V., Suderman, M., Hagenbeek, F. A., Caramaschi, D., Hottenga, J. J., Pool, R., Dolan, C. V., Ligthart, L., van Beijsterveldt, C. E. M., Willemsen, G., de Geus, E. J. C., Beck, J. J., Ehli, E. A., Cuellar-Partida, G., Evans, D. M., Medland, S. E., Relton, C. L., Boomsma, D. I., van Dongen, J., ... Schalkwijk, C. G. (2022). DNA methylation in peripheral tissues and left-handedness. Scientific Reports, 12(1), Article 5606. https://doi.org/10.1038/s41598-022-08998-0
- Zeijen, V. J. M., Lafeber, M., Versmissen, J., Kroon, A. A., Boersma, E., & Daemen, J. (2022). Adequacy of blood pressure control in high-risk hypertensive patients: The DEGREE study. International Journal of Cardiology, 352, 137-143. https://doi.org/10.1016/j.ijcard.2022.02.014
- Mashnafi, S., Plat, J., Mensink, R. P., Joris, P. J., Kusters, Y. H. A. M., Houben, A. J. H. M., Stehouwer, C. D. A., Schalkwijk, C. G., & Baumgartner, S. (2022). Effects of Diet-Induced Weight Loss on Plasma Markers for Cholesterol Absorption and Synthesis: Secondary Analysis of a Randomized Trial in Abdominally Obese Men. Nutrients, 14(8), Article 1546. https://doi.org/10.3390/nu14081546
- Simons, P. I. H. G., Cornelissen, M. E. B., Valkenburg, O., Onland-Moret, N. C., van der Schouw, Y. T., Stehouwer, C. D. A., Burgess, S., & Brouwers, M. C. G. J. (2022). Causal relationship between polycystic ovary syndrome and coronary artery disease: A Mendelian randomisation study. Clinical Endocrinology, 96(4), 599-604. https://doi.org/10.1111/cen.14593




