• 2019
    • Gennip, A. C. E. V., Broers, N. J. H., Meulen, K. J. T., Canaud, B., Christiaans, M. H. L., Cornelis, T., Gelens, M. A. C. J., Hermans, M. M. H., Konings, C. J. A. M., Net, J. B. V. D., Sande, F. M. V. D., Schalkwijk, C. G., Stifft, F., Wirtz, J. J. J. M., Kooman, J. P., & Martens, R. J. H. (2019). Endothelial dysfunction and low-grade inflammation in the transition to renal replacement therapy. PLOS ONE, 14(9), Article e0222547. https://doi.org/10.1371/journal.pone.0222547
    • Ahluwalia, T. S., Tofte, N., Vogelzangs, N., Mook-Kanamori, D., Brahimaj, A., Frimodt-Moller, M., Arts, I., Beulens, J., van der Heijden, A., Stehouwer, C., Nijpels, G., van Greevenbroek, M., van der Kallen, C., Rossing, P., & 't Hart, L. M. (2019). Plasma metabolomics identifies markers of kidney function in 3,064 Europeans with type 2 diabetes. Diabetologia, 62, S456-S456.
    • Hertroijs, D. F. L., Brouwers, M. C. G. J., Elissen, A. M. J., Schaper, N. C., & Ruwaard, D. (2019). Relevant patient characteristics for estimating healthcare needs according to healthcare providers and people with type 2 diabetes: a Delphi survey. BMC Health Services Research, 19(1), Article 575. https://doi.org/10.1186/s12913-019-4371-z
    • Martens, R. J. H., Broers, N. J. H., Canaud, B., Christiaans, M. H. L., Cornelis, T., Gauly, A., Hermans, M. M. H., Konings, C. J. A. M., van Der Sande, F. M., Scheijen, J. L. J. M., Stifft, F., Wirtz, J. J. J. M., Kooman, J. P., & Schalkwijk, C. G. (2019). Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study. PLOS ONE, 14(8), Article 0221058. https://doi.org/10.1371/journal.pone.0221058
    • van Der Plaat, D., Vonk, J. M., Terzikhan, N., de Jong, K., de Vries, M., La Bastide-van Gemert, S., van Diemen, C. C., Lahousse, L., Brusselle, G., Nedeljkovic, I., Amin, N., Kromhout, H., Vermeulen, R. C. H., Postma, D. S., van Duijn, C. M., Boezen, H. M., Heijmans, B. T., Hoen, P. A. C. T., van Meurs, J., ... BIOS Consortium (2019). Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression. Human Molecular Genetics, 28(15), 2477-2485. https://doi.org/10.1093/hmg/ddz067
    • Mandaviya, P. R., Joehanes, R., Brody, J., Castillo-Fernandez, J. E., Dekkers, K. F., Do, A. N., Graff, M., Hänninen, I. K., Tanaka, T., de Jonge, E. A. L., Kiefte-de Jong, J. C., Absher, D. M., Aslibekyan, S., de Rijke, Y. B., Fornage, M., Hernandez, D. G., Hurme, M. A., Ikram, M. A., Jacques, P. F., ... BIOS Consortium, CHARGE Consortium Epigenetics Working Group, CHARGE Consortium Nutrition Working Group (2019). Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals. American Journal of Clinical Nutrition, 110(2), 437-450. Article 15. https://doi.org/10.1093/ajcn/nqz031
    • Maasen, K., van Greevenbroek, M. M. J., Scheijen, J. L. J. M., van der Kallen, C. J. H., Stehouwer, C. D. A., & Schalkwijk, C. G. (2019). High dietary glycemic load is associated with higher concentrations of urinary advanced glycation endproducts: the Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study. American Journal of Clinical Nutrition, 110(2), 358-366. https://doi.org/10.1093/ajcn/nqz119
    • Porcu, E., Rueger, S., Lepik, K., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Bonder, M. J., Boomsma, D., Christiansen, M., Claringbould, A., Deelen, P., Esko, T., Fave, M.-J., Franke, L., ... Kutalik, Z. (2019). Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits. Nature Communications, 10, Article 3300. https://doi.org/10.1038/s41467-019-10936-0
    • Tuin, J., Stassen, P. M., Bogdan, D. I., Broekroelofs, J., van Paassen, P., Tervaert, J. W. C., Sanders, J.-S., & Stegeman, C. A. (2019). Mycophenolate Mofetil Versus Cyclophosphamide for the Induction of Remission in Nonlife-Threatening Relapses of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Randomized, Controlled Trial. Clinical journal of the American Society of Nephrology, 14(7), 1021-1028. https://doi.org/10.2215/CJN.11801018
    • Telgenkamp, I., Kusters, Y. H. A. M., Schalkwijk, C. G., Houben, A. J. H. M., Kooi, M. E., Lindeboom, L., Bons, J. A. P., Schaper, N. C., Joris, P. J., Plat, J., Mensink, R. P., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2019). Contribution of Liver Fat to Weight Loss-Induced Changes in Serum Hepatokines: A Randomized Controlled Trial. Journal of Clinical Endocrinology & Metabolism, 104(7), 2719-2727. https://doi.org/10.1210/jc.2018-02378
    • Hanssen, N. M. J., & Jandeleit-Dahm, K. A. M. (2019). Dipeptidyl peptidase-4 inhibitors and cardiovascular and renal disease in type 2 diabetes: What have we learned from the CARMELINA trial?Diabetes & Vascular Disease Research, 16(4), 303-309. https://doi.org/10.1177/1479164119842339
    • Hooijschuur, M. C. E., Ghossein-Doha, C., Kroon, A. A., De Leeuw, P. W., Zandbergen, A. A. M., Van Kuijk, S. M. J., & Spaanderman, M. E. A. (2019). Metabolic syndrome and pre-eclampsia. Ultrasound in Obstetrics & Gynecology, 54(1), 64-71. https://doi.org/10.1002/uog.20126
    • O'Donovan, S. D., Lenz, M., Goossens, G. H., van der Kallen, C. J. H., Eussen, S. J. M. P., Stehouwer, C. D. A., van Greevenbroek, M. M., Schram, M. T., Sep, S. J., Peeters, R. L. M., Blaak, E. E., van Riel, N. A. W., de Kok, T. M. C. M., & Arts, I. C. W. (2019). Improved quantification of muscle insulin sensitivity using oral glucose tolerance test data: the MISI Calculator. Scientific Reports, 9, Article 9388. https://doi.org/10.1038/s41598-019-45858-w
    • Obeid, R., Heil, S. G., Verhoeven, M. M. A., van den Heuvel, E. G. H. M., de Groot, L. C. P. G. M., & Eussen, S. J. P. M. (2019). Vitamin B12 Intake From Animal Foods, Biomarkers, and Health Aspects. Frontiers in nutrition, 6, Article 93. https://doi.org/10.3389/fnut.2019.00093
    • Lisan, Q., Van Sloten, T., Vidal, P. M., Rubio, J. H., Heinzer, R., & Empana, J. P. (2019). Association of Positive Airway Pressure Prescription With Mortality in Patients With Obesity and Severe Obstructive Sleep Apnea: The Sleep Heart Health Study. JAMA Otolaryngology - Head and Neck Surgery, 145(6), 509-515. https://doi.org/10.1001/jamaoto.2019.0281
    • Climie, R. E., Boutouyrie, P., Perier, M.-C., Guibout, C., van Sloten, T. T., Thomas, F., Danchin, N., Sharman, J. E., Laurent, S., Jouven, X., & Empana, J.-P. (2019). Individual and Neighborhood Deprivation and Carotid Stiffness: The Paris Prospective Study III. Hypertension, 73(6), 1185-1194. https://doi.org/10.1161/HYPERTENSIONAHA.118.12186
    • Climie, R. E., van Sloten, T. T., Bruno, R.-M., Taddei, S., Empana, J.-P., Stehouwer, C. D. A., Sharman, J. E., Boutouyrie, P., & Laurent, S. (2019). Macrovasculature and Microvasculature at the Crossroads Between Type 2 Diabetes Mellitus and Hypertension. Hypertension, 73(6), 1138-1149. https://doi.org/10.1161/HYPERTENSIONAHA.118.11769
    • van Dongen, M. C. J. M., Wijckmans-Duysens, N. E. G., den Biggelaar, L. J. C. J., Ocke, M. C., Meijboom, S., Brants, H. A. M., de Vries, J. H. M., Feskens, E. J. M., Bueno-de-Mesquita, H. B., Geelen, A., Stehouwer, C. D. A., Dagnelie, P. C., & Eussen, S. J. P. M. (2019). The Maastricht FFQ: Development and validation of a comprehensive food frequency questionnaire for the Maastricht study. Nutrition, 62, 39-46. https://doi.org/10.1016/j.nut.2018.10.015
    • Lay-Flurrie, S., Stevens, R., de Leeuw, P., Kroon, A., Greenfield, S., Mohammed, M., Gill, P., Verberk, W., & McManus, R. (2019). Using out-of-office blood pressure measurements in established cardiovascular risk scores: a secondary analysis of data from two blood pressure monitoring studies. British Journal of General Practice, 69(683), E381-E388. https://doi.org/10.3399/bjgp19X702737
    • Tinnevelt, G. H., van Staveren, S., Wouters, K., Wijnands, E., Verboven, K., Folcarelli, R., Koenderman, L., Buydens, L. M. C., & Jansen, J. J. (2019). A novel data fusion method for the effective analysis of multiple panels of flow cytometry data. Scientific Reports, 9(1), Article 6777. https://doi.org/10.1038/s41598-019-43166-x
    • Paumelle, R., Haas, J. T., Hennuyer, N., Bauge, E., Deleye, Y., Mesotten, D., Langouche, L., Vanhoutte, J., Cudejko, C., Wouters, K., Hannou, S. A., Legry, V., Lancel, S., Lalloyer, F., Polizzi, A., Smati, S., Gourdy, P., Vallez, E., Bouchaert, E., ... Staels, B. (2019). Hepatic PPARα is critical in the metabolic adaptation to sepsis. Journal of Hepatology, 70(5), 963-973. https://doi.org/10.1016/j.jhep.2018.12.037
    • Kuiper, A., Grunewald, S., Murphy, E., Coenen, M. A., Eggink, H., Zutt, R., Rubio-Gozalbo, M. E., Bosch, A. M., Williams, M., Derks, T. G. J., Lachmann, R. H. L., Brouwers, M. C. G. J., Janssen, M. C. H., Tijssen, M. A., & de Koning, T. J. (2019). Movement disorders and nonmotor neuropsychological symptoms in children and adults with classical galactosemia. Journal of Inherited Metabolic Disease, 42(3), 451-458. https://doi.org/10.1002/jimd.12054
    • CODAM study (2019). Plasma lipid profiling of tissue-specific insulin resistance in human obesity. International Journal of Obesity, 43(5), 989-998. https://doi.org/10.1038/s41366-018-0189-8
    • Lindekilde, N., Nefs, G., Henriksen, J. E., Lasgaard, M., Schram, M., Rubin, K., Rutters, F., Kivimaki, M., & Pouwer, F. (2019). Psychiatric disorders as risk factors for the development of type 2 diabetes mellitus: an umbrella review protocol. BMJ Open, 9(5), Article e024981. https://doi.org/10.1136/bmjopen-2018-024981
    • Wetzels, S., Vanmierlo, T., Scheijen, J. L. J. M., van Horssen, J., Amor, S., Somers, V., Schalkwijk, C. G., Hendriks, J. J. A., & Wouters, K. (2019). Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions. Frontiers in Immunology, 10, Article 855. https://doi.org/10.3389/fimmu.2019.00855
    • Qi, Y., Koster, A., van Boxtel, M., Köhler, S., Schram, M., Schaper, N., Stehouwer, C., & Bosma, H. (2019). Adulthood Socioeconomic Position and Type 2 Diabetes Mellitus-A Comparison of Education, Occupation, Income, and Material Deprivation: The Maastricht Study. International Journal of Environmental Research and Public Health, 16(8), Article 1435. https://doi.org/10.3390/ijerph16081435
    • Onderwater, G. L. J., Ligthart, L., Bot, M., Demirkan, A., Fu, J., van der Kallen, C. J. H., Vijfhuizen, L. S., Pool, R., Liu, J., Vanmolkot, F. H. M., Beekman, M., Wen, K., Amin, N., Thesing, C. S., Pijpers, J. A., Kies, D. A., Zielman, R., de Boer, I., van Greevenbroek, M. M. J., ... BBMRI Metabolomics Consortium (2019). Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine. Neurology, 92(16), E1899-E1911. https://doi.org/10.1212/WNL.0000000000007313
    • Zhou, T. L., Kroon, A. A., Sloten, T. T. V., van Boxtel, M. P. J., Verhey, F. R. J., Schram, M. T., Köhler, S., Stehouwer, C. D. A., & Henry, R. M. A. (2019). Greater Blood Pressure Variability Is Associated With Lower Cognitive Performance: The Maastricht Study. Hypertension, 73(4), 803–811. https://doi.org/10.1161/hypertensionaha.118.12305
    • Plat, J., Baumgartner, S., Vanmierlo, T., Luetjohann, D., Calkins, K. L., Burrin, D. G., Guthrie, G., Thijs, C., Te Velde, A. A., Vreugdenhil, A. C. E., Sverdlov, R., Garssen, J., Wouters, K., Trautwein, E. A., Wolfs, T. G., van Gorp, C., Mulder, M. T., Riksen, N. P., Groen, A. K., & Mensink, R. P. (2019). Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?". Progress in Lipid Research, 74, 87-102. https://doi.org/10.1016/j.plipres.2019.02.003
    • Brouwers, M. C. G. J., Simons, N., Stehouwer, C. D. A., Koek, G. H., Schaper, N. C., & Isaacs, A. (2019). Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease. Hepatology communications, 3(4), 587-596. https://doi.org/10.1002/hep4.1319
    • van Sloten, T. T., Boutouyrie, P., Tafflet, M., Offredo, L., Thomas, F., Guibout, C., Climie, R. E., Lemogne, C., Pannier, B., Laurent, S., Jouven, X., & Empana, J.-P. (2019). Carotid Artery Stiffness and Incident Depressive Symptoms: The Paris Prospective Study III. Biological Psychiatry, 85(6), 498-505. https://doi.org/10.1016/j.biopsych.2018.09.018
    • Sluimer, J. C., & Houben, A. J. H. M. (2019). Joint ESM-EVBO meetings: past, present, and future. Cardiovascular Research, 115(4), E46-E48. https://doi.org/10.1093/cvr/cvz041
    • Zelis, N., Buijs, J., de Leeuw, P. W., van Kuijk, S. M. J., & Stassen, P. M. (2019). Study protocol for a multicentre prospective cohort study to identify predictors of adverse outcome in older medical emergency department patients (the Risk Stratification in the Emergency Department in Acutely Ill Older Patients (RISE UP) study). BMC Geriatrics, 19, Article 65. https://doi.org/10.1186/s12877-019-1078-2
    • den Biggelaar, L. J. C. J., Eussen, S. J. P. M., Sep, S. J. S., Mari, A., Ferrannini, E., van Greevenbroek, M. M., van der Kallen, C. J., Schalkwijk, C. G., Arts, I. C. W., Stehouwer, C. D. A., & Dagnelie, P. C. (2019). Prospective associations of dietary carbohydrate, fat, and protein intake with β-cell function in the CODAM study. European Journal of Nutrition, 58(2), 597-608. https://doi.org/10.1007/s00394-018-1644-y
    • Shvetsova, E., Sofronova, A., Monajemi, R., Gagalova, K., Draisma, H. H. M., White, S. J., Santen, G. W. E., Lopes, S. M. C. D. S., Heijmans, B. T., van Meurs, J., Jansen, R., Franke, L., Kielbasa, S. M., den Dunnen, J. T., 't Hoen, P. A. C., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., ... GoNL consortium (2019). Skewed X-inactivation is common in the general female population. European Journal of Human Genetics, 27(3), 455-465. https://doi.org/10.1038/s41431-018-0291-3
    • Lisan, Q., Tafflet, M., Thomas, F., Boutouyrie, P., Guibout, C., Haba-Rubio, J., Climie, R., Perier, M. C., Van Sloten, T., Pannier, B., Marques-Vidal, P., Jouven, X., & Empana, J. P. (2019). Body Silhouette Trajectories Over the Lifespan and Insomnia Symptoms: The Paris Prospective Study 3. Scientific Reports, 9, 1-9. Article 1581. https://doi.org/10.1038/s41598-018-38145-7
    • Latten, G. H. P., Claassen, L., Jonk, M., Cals, J. W. L., Muris, J. W. M., & Stassen, P. M. (2019). Characteristics of the prehospital phase of adult emergency department patients with an infection: A prospective pilot study. PLOS ONE, 14(2), Article 0212181. https://doi.org/10.1371/journal.pone.0212181
    • Bijnen, M., van de Gaar, J., Vroomen, M., Gijbels, M. J., de Winther, M., Schalkwijk, C. G., & Wouters, K. (2019). Adipose tissue macrophages do not affect atherosclerosis development in mice. Atherosclerosis, 281, 31-37. https://doi.org/10.1016/j.atherosclerosis.2018.12.010
    • van der Waaij, K. M., Heusinkveld, M. H. G., Delhaas, T., Kroon, A. A., & Reesink, K. D. (2019). Do treatment-induced changes in arterial stiffness affect left ventricular structure? A meta-analysis. Journal of Hypertension, 37(2), 253-263. https://doi.org/10.1097/HJH.0000000000001918
    • Nielen, J. T. H., Dagnelie, P. C., Boonen, A., Klungel, O., van den Bemt, B., & de Vries, F. (2019). Impact of the definition of osteoarthritis and of the timing of its onset on the association between type 2 diabetes mellitus and osteoarthritis: Clinical Practice Research Datalink. Diabetes Research and Clinical Practice, 148, 240-248. https://doi.org/10.1016/j.diabres.2019.01.021
    • Driessen, J. H. M., de Vries, F., van Onzenoort, H. A. W., Schram, M. T., van der Kallen, C., Reesink, K. D., Sep, S., Stehouwer, C. D. A., Schaper, N., Kroon, A. A., Schalkwijk, C., van den Bergh, J. P. W., & Henry, R. M. A. (2019). Metformin use in type 2 diabetic patients is not associated with lower arterial stiffness: the Maastricht Study. Journal of Hypertension, 37(2), 365-371. https://doi.org/10.1097/HJH.0000000000001892
    • Nokin, M.-J., Bellier, J., Durieux, F., Peulen, O., Rademaker, G., Gabriel, M., Monseur, C., Charloteaux, B., Verbeke, L., van Laere, S., Roncarati, P., Herfs, M., Lambert, C., Scheijen, J., Schalkwijk, C., Colige, A., Caers, J., Delvenne, P., Turtoi, A., ... Bellahcene, A. (2019). Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. Breast Cancer Research, 21, Article 11. https://doi.org/10.1186/s13058-018-1095-7
    • Cobussen, M., Stassen, P. M., Posthouwer, D., van Tiel, F. H., Savelkoul, P. H. M., Havenith, T., & Haeseker, M. B. (2019). Improving peak concentrations of a single dose regime of gentamicin in patients with sepsis in the emergency department. PLOS ONE, 14(1), Article 0210012. https://doi.org/10.1371/journal.pone.0210012
    • Zelis, N., Mauritz, A. N., Kuijpers, L. I. J., Buijs, J., de Leeuw, P. W., & Stassen, P. M. (2019). Short-term mortality in older medical emergency patients can be predicted using clinical intuition: A prospective study. PLOS ONE, 14(1), Article 0208741. https://doi.org/10.1371/journal.pone.0208741
    • Nielen, J. T. H., de Vries, F., van der Velde, J. H. P. M., Savelberg, H. H. C. M., Schaper, N. C., Dagnelie, P. C., Henry, R. M. A., Schram, M., Stehouwer, C. D. A., Boonen, A., Koster, A., & van den Bemt, B. J. F. (2019). The Association Between β-Blocker Use and Cardiorespiratory Fitness: The Maastricht Study. Journal of Cardiovascular Pharmacology and Therapeutics, 24(1), 37-45. https://doi.org/10.1177/1074248418778551
    • Luijten, J., van Greevenbroek, M. M. J., Schaper, N. C., Meex, S. J. R., van der Steen, C., Meijer, L. J., de Boer, D., de Graaf, J., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2019). Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study. Atherosclerosis, 280, 1-6. https://doi.org/10.1016/j.atherosclerosis.2018.11.013
    • Denissen, K. F. M., Heil, S. G., Eussen, S. J. P. M., Heeskens, J. P. J., Thijs, C., Mommers, M., Smits, L. J. M., van Dongen, M. C. J. M., & Dagnelie, P. C. (2019). Intakes of Vitamin B-12 from Dairy Food, Meat, and Fish and Shellfish Are Independently and Positively Associated with Vitamin B-12 Biomarker Status in Pregnant Dutch Women. Journal of Nutrition, 149(1), 131-138. https://doi.org/10.1093/jn/nxy233
    • Hanssen, N. M. J., Stehouwer, C. D. A., & Schalkwijk, C. G. (2019). Methylglyoxal stress, the glyoxalase system, and diabetic chronic kidney disease. Current Opinion in Nephrology and Hypertension, 28(1), 26-33. https://doi.org/10.1097/MNH.0000000000000465
    • van Twist, D. J. L., de Leeuw, P. W., Spiering, W., Rossi, G. P., Dominiczak, A. F., Jennings, G. L. R., Barigou, M., Persu, A., & Kroon, A. A. (2019). Unifocal and Multifocal Fibromuscular Dysplasia: Two Different Disease Entities in a Single Patient?Hypertension, 73(1), 7-12. https://doi.org/10.1161/HYPERTENSIONAHA.118.12004
    • Schols, A. M. R., Willemsen, R. T. A., Bonten, T. N., Rutten, M. H., Stassen, P. M., Kietselaer, B. L. J. H., Dinant, G.-J., & Cals, J. W. L. (2019). A Nationwide Flash-Mob Study for Suspected Acute Coronary Syndrome. Annals of Family Medicine, 17(4), 296-303. https://doi.org/10.1370/afm.2401