• 2019
    • Paumelle, R., Haas, J. T., Hennuyer, N., Bauge, E., Deleye, Y., Mesotten, D., Langouche, L., Vanhoutte, J., Cudejko, C., Wouters, K., Hannou, S. A., Legry, V., Lancel, S., Lalloyer, F., Polizzi, A., Smati, S., Gourdy, P., Vallez, E., Bouchaert, E., ... Staels, B. (2019). Hepatic PPARα is critical in the metabolic adaptation to sepsis. Journal of Hepatology, 70(5), 963-973. https://doi.org/10.1016/j.jhep.2018.12.037
    • Kuiper, A., Grunewald, S., Murphy, E., Coenen, M. A., Eggink, H., Zutt, R., Rubio-Gozalbo, M. E., Bosch, A. M., Williams, M., Derks, T. G. J., Lachmann, R. H. L., Brouwers, M. C. G. J., Janssen, M. C. H., Tijssen, M. A., & de Koning, T. J. (2019). Movement disorders and nonmotor neuropsychological symptoms in children and adults with classical galactosemia. Journal of Inherited Metabolic Disease, 42(3), 451-458. https://doi.org/10.1002/jimd.12054
    • CODAM study (2019). Plasma lipid profiling of tissue-specific insulin resistance in human obesity. International Journal of Obesity, 43(5), 989-998. https://doi.org/10.1038/s41366-018-0189-8
    • Lindekilde, N., Nefs, G., Henriksen, J. E., Lasgaard, M., Schram, M., Rubin, K., Rutters, F., Kivimaki, M., & Pouwer, F. (2019). Psychiatric disorders as risk factors for the development of type 2 diabetes mellitus: an umbrella review protocol. BMJ Open, 9(5), Article e024981. https://doi.org/10.1136/bmjopen-2018-024981
    • Wetzels, S., Vanmierlo, T., Scheijen, J. L. J. M., van Horssen, J., Amor, S., Somers, V., Schalkwijk, C. G., Hendriks, J. J. A., & Wouters, K. (2019). Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions. Frontiers in Immunology, 10, Article 855. https://doi.org/10.3389/fimmu.2019.00855
    • Qi, Y., Koster, A., van Boxtel, M., Köhler, S., Schram, M., Schaper, N., Stehouwer, C., & Bosma, H. (2019). Adulthood Socioeconomic Position and Type 2 Diabetes Mellitus-A Comparison of Education, Occupation, Income, and Material Deprivation: The Maastricht Study. International Journal of Environmental Research and Public Health, 16(8), Article 1435. https://doi.org/10.3390/ijerph16081435
    • Onderwater, G. L. J., Ligthart, L., Bot, M., Demirkan, A., Fu, J., van der Kallen, C. J. H., Vijfhuizen, L. S., Pool, R., Liu, J., Vanmolkot, F. H. M., Beekman, M., Wen, K., Amin, N., Thesing, C. S., Pijpers, J. A., Kies, D. A., Zielman, R., de Boer, I., van Greevenbroek, M. M. J., ... BBMRI Metabolomics Consortium (2019). Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine. Neurology, 92(16), E1899-E1911. https://doi.org/10.1212/WNL.0000000000007313
    • Zhou, T. L., Kroon, A. A., Sloten, T. T. V., van Boxtel, M. P. J., Verhey, F. R. J., Schram, M. T., Köhler, S., Stehouwer, C. D. A., & Henry, R. M. A. (2019). Greater Blood Pressure Variability Is Associated With Lower Cognitive Performance: The Maastricht Study. Hypertension, 73(4), 803–811. https://doi.org/10.1161/hypertensionaha.118.12305
    • Plat, J., Baumgartner, S., Vanmierlo, T., Luetjohann, D., Calkins, K. L., Burrin, D. G., Guthrie, G., Thijs, C., Te Velde, A. A., Vreugdenhil, A. C. E., Sverdlov, R., Garssen, J., Wouters, K., Trautwein, E. A., Wolfs, T. G., van Gorp, C., Mulder, M. T., Riksen, N. P., Groen, A. K., & Mensink, R. P. (2019). Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?". Progress in Lipid Research, 74, 87-102. https://doi.org/10.1016/j.plipres.2019.02.003
    • Brouwers, M. C. G. J., Simons, N., Stehouwer, C. D. A., Koek, G. H., Schaper, N. C., & Isaacs, A. (2019). Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease. Hepatology communications, 3(4), 587-596. https://doi.org/10.1002/hep4.1319
    • van Sloten, T. T., Boutouyrie, P., Tafflet, M., Offredo, L., Thomas, F., Guibout, C., Climie, R. E., Lemogne, C., Pannier, B., Laurent, S., Jouven, X., & Empana, J.-P. (2019). Carotid Artery Stiffness and Incident Depressive Symptoms: The Paris Prospective Study III. Biological Psychiatry, 85(6), 498-505. https://doi.org/10.1016/j.biopsych.2018.09.018
    • Sluimer, J. C., & Houben, A. J. H. M. (2019). Joint ESM-EVBO meetings: past, present, and future. Cardiovascular Research, 115(4), E46-E48. https://doi.org/10.1093/cvr/cvz041
    • Zelis, N., Buijs, J., de Leeuw, P. W., van Kuijk, S. M. J., & Stassen, P. M. (2019). Study protocol for a multicentre prospective cohort study to identify predictors of adverse outcome in older medical emergency department patients (the Risk Stratification in the Emergency Department in Acutely Ill Older Patients (RISE UP) study). BMC Geriatrics, 19, Article 65. https://doi.org/10.1186/s12877-019-1078-2
    • den Biggelaar, L. J. C. J., Eussen, S. J. P. M., Sep, S. J. S., Mari, A., Ferrannini, E., van Greevenbroek, M. M., van der Kallen, C. J., Schalkwijk, C. G., Arts, I. C. W., Stehouwer, C. D. A., & Dagnelie, P. C. (2019). Prospective associations of dietary carbohydrate, fat, and protein intake with β-cell function in the CODAM study. European Journal of Nutrition, 58(2), 597-608. https://doi.org/10.1007/s00394-018-1644-y
    • Shvetsova, E., Sofronova, A., Monajemi, R., Gagalova, K., Draisma, H. H. M., White, S. J., Santen, G. W. E., Lopes, S. M. C. D. S., Heijmans, B. T., van Meurs, J., Jansen, R., Franke, L., Kielbasa, S. M., den Dunnen, J. T., 't Hoen, P. A. C., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., ... GoNL consortium (2019). Skewed X-inactivation is common in the general female population. European Journal of Human Genetics, 27(3), 455-465. https://doi.org/10.1038/s41431-018-0291-3
    • Lisan, Q., Tafflet, M., Thomas, F., Boutouyrie, P., Guibout, C., Haba-Rubio, J., Climie, R., Perier, M. C., Van Sloten, T., Pannier, B., Marques-Vidal, P., Jouven, X., & Empana, J. P. (2019). Body Silhouette Trajectories Over the Lifespan and Insomnia Symptoms: The Paris Prospective Study 3. Scientific Reports, 9, 1-9. Article 1581. https://doi.org/10.1038/s41598-018-38145-7
    • Latten, G. H. P., Claassen, L., Jonk, M., Cals, J. W. L., Muris, J. W. M., & Stassen, P. M. (2019). Characteristics of the prehospital phase of adult emergency department patients with an infection: A prospective pilot study. PLOS ONE, 14(2), Article 0212181. https://doi.org/10.1371/journal.pone.0212181
    • Bijnen, M., van de Gaar, J., Vroomen, M., Gijbels, M. J., de Winther, M., Schalkwijk, C. G., & Wouters, K. (2019). Adipose tissue macrophages do not affect atherosclerosis development in mice. Atherosclerosis, 281, 31-37. https://doi.org/10.1016/j.atherosclerosis.2018.12.010
    • van der Waaij, K. M., Heusinkveld, M. H. G., Delhaas, T., Kroon, A. A., & Reesink, K. D. (2019). Do treatment-induced changes in arterial stiffness affect left ventricular structure? A meta-analysis. Journal of Hypertension, 37(2), 253-263. https://doi.org/10.1097/HJH.0000000000001918
    • Nielen, J. T. H., Dagnelie, P. C., Boonen, A., Klungel, O., van den Bemt, B., & de Vries, F. (2019). Impact of the definition of osteoarthritis and of the timing of its onset on the association between type 2 diabetes mellitus and osteoarthritis: Clinical Practice Research Datalink. Diabetes Research and Clinical Practice, 148, 240-248. https://doi.org/10.1016/j.diabres.2019.01.021
    • Driessen, J. H. M., de Vries, F., van Onzenoort, H. A. W., Schram, M. T., van der Kallen, C., Reesink, K. D., Sep, S., Stehouwer, C. D. A., Schaper, N., Kroon, A. A., Schalkwijk, C., van den Bergh, J. P. W., & Henry, R. M. A. (2019). Metformin use in type 2 diabetic patients is not associated with lower arterial stiffness: the Maastricht Study. Journal of Hypertension, 37(2), 365-371. https://doi.org/10.1097/HJH.0000000000001892
    • Nokin, M.-J., Bellier, J., Durieux, F., Peulen, O., Rademaker, G., Gabriel, M., Monseur, C., Charloteaux, B., Verbeke, L., van Laere, S., Roncarati, P., Herfs, M., Lambert, C., Scheijen, J., Schalkwijk, C., Colige, A., Caers, J., Delvenne, P., Turtoi, A., ... Bellahcene, A. (2019). Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. Breast Cancer Research, 21, Article 11. https://doi.org/10.1186/s13058-018-1095-7
    • Cobussen, M., Stassen, P. M., Posthouwer, D., van Tiel, F. H., Savelkoul, P. H. M., Havenith, T., & Haeseker, M. B. (2019). Improving peak concentrations of a single dose regime of gentamicin in patients with sepsis in the emergency department. PLOS ONE, 14(1), Article 0210012. https://doi.org/10.1371/journal.pone.0210012
    • Zelis, N., Mauritz, A. N., Kuijpers, L. I. J., Buijs, J., de Leeuw, P. W., & Stassen, P. M. (2019). Short-term mortality in older medical emergency patients can be predicted using clinical intuition: A prospective study. PLOS ONE, 14(1), Article 0208741. https://doi.org/10.1371/journal.pone.0208741
    • Nielen, J. T. H., de Vries, F., van der Velde, J. H. P. M., Savelberg, H. H. C. M., Schaper, N. C., Dagnelie, P. C., Henry, R. M. A., Schram, M., Stehouwer, C. D. A., Boonen, A., Koster, A., & van den Bemt, B. J. F. (2019). The Association Between β-Blocker Use and Cardiorespiratory Fitness: The Maastricht Study. Journal of Cardiovascular Pharmacology and Therapeutics, 24(1), 37-45. https://doi.org/10.1177/1074248418778551
    • Luijten, J., van Greevenbroek, M. M. J., Schaper, N. C., Meex, S. J. R., van der Steen, C., Meijer, L. J., de Boer, D., de Graaf, J., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2019). Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study. Atherosclerosis, 280, 1-6. https://doi.org/10.1016/j.atherosclerosis.2018.11.013
    • Denissen, K. F. M., Heil, S. G., Eussen, S. J. P. M., Heeskens, J. P. J., Thijs, C., Mommers, M., Smits, L. J. M., van Dongen, M. C. J. M., & Dagnelie, P. C. (2019). Intakes of Vitamin B-12 from Dairy Food, Meat, and Fish and Shellfish Are Independently and Positively Associated with Vitamin B-12 Biomarker Status in Pregnant Dutch Women. Journal of Nutrition, 149(1), 131-138. https://doi.org/10.1093/jn/nxy233
    • Hanssen, N. M. J., Stehouwer, C. D. A., & Schalkwijk, C. G. (2019). Methylglyoxal stress, the glyoxalase system, and diabetic chronic kidney disease. Current Opinion in Nephrology and Hypertension, 28(1), 26-33. https://doi.org/10.1097/MNH.0000000000000465
    • van Twist, D. J. L., de Leeuw, P. W., Spiering, W., Rossi, G. P., Dominiczak, A. F., Jennings, G. L. R., Barigou, M., Persu, A., & Kroon, A. A. (2019). Unifocal and Multifocal Fibromuscular Dysplasia: Two Different Disease Entities in a Single Patient?Hypertension, 73(1), 7-12. https://doi.org/10.1161/HYPERTENSIONAHA.118.12004
    • Schols, A. M. R., Willemsen, R. T. A., Bonten, T. N., Rutten, M. H., Stassen, P. M., Kietselaer, B. L. J. H., Dinant, G.-J., & Cals, J. W. L. (2019). A Nationwide Flash-Mob Study for Suspected Acute Coronary Syndrome. Annals of Family Medicine, 17(4), 296-303. https://doi.org/10.1370/afm.2401
    • Tsioufis, C., de Leeuw, P., Dimitriadis, K., Kasiakogias, A., Kroon, A., Lombardi, C., & Parati, G. (2019). European Society of Hypertension Scientific Newsletter: Update on Hypertension Management 2017; 18: Nr. 65 Update on Device Therapies for resistant hypertension Device-Therapie bei therapieresistenter Hypertonie - Update. Journal fur Hypertonie, 23(2), 49-52. https://www.kup.at/kup/pdf/14515.pdf
    • Bijnen, M., van Greevenbroek, M. M. J., van Der Kallen, C. J. H., Scheijen, J. L., van de Waarenburg, M. P. H., Stehouwer, C. D. A., Wouters, K., & Schallcwijk, C. G. (2019). Hepatic Fat Content and Liver Enzymes Are Associated with Circulating Free and Protein-Bound Advanced Glycation End Products, Which Are Associated with Low-Grade Inflammation: The CODAM Study. Journal of Diabetes Research, 2019, Article 6289831. https://doi.org/10.1155/2019/6289831
    • Wachelder, J., Stassen, P. M., Fourmanov, R. S., Nickel, C. H., & Haak, H. R. (2019). Higher In-Hospital Mortality in Patients with Nonspecific Complaints Presenting to the Emergency Department. Acute Medicine, 18(4), 232-238. https://doi.org/10.52964/amja.0782
    • Rensma, S., van Sloten, T. T., Houben, A. J. H. M., van Boxtel, M. P. J., Berendschot, T. T. J. M., Jansen, J. F. A., Kroon, A. A., Koster, A., Backes, W. H., Schaper, N., Dinant, G. J., Schalkwijk, C. G., Henry, R. M. A., Wolfs, E. M. L., van Heumen, M. J. A., Schram, M. T., & Stehouwer, C. D. A. (2019). Microvascular Dysfunction Is Associated with Worse Cognitive Performance: The Maastricht Study. Journal of Vascular Research, 56(S1), 94-94.
  • 2018
    • van Dongen, J., Bonder, M. J., Dekkers, K. F., Nivard, M. G., van Iterson, M., Willemsen, G., Beekman, M., van der Spek, A., van Meurs, J. B. J., Franke, L., Heijmans, B. T., van Duijn, C. M., Slagboom, P. E., Boomsma, D. I., ’t Hoen, P. A. C., Isaacs, A., Jansen, R., Pool, R., Hottenga, J. J., ... BIOS Consortium (2018). DNA methylation signatures of educational attainment. npj Science of Learning, 3(1), Article 7. https://doi.org/10.1038/s41539-018-0020-2
    • van Agtmaal, M. J. M., Houben, A. J. H. M., de Wit, V., Henry, R. M. A., Schaper, N. C., Dagnelie, P. C., van der Kallen, C. J., Koster, A., Sep, S. J., Kroon, A. A., Jansen, J. F. A., Hofman, P. A., Backes, W. H., Schram, M. T., & Stehouwer, C. D. A. (2018). Prediabetes Is Associated With Structural Brain Abnormalities: The Maastricht Study. Diabetes Care, 41(12), 2535-2543. https://doi.org/10.2337/dc18-1132
    • de Leeuw, P. W., & Kroon, A. A. (2018). A sluice to normotension?Journal of Hypertension, 36(12), 2314-2315. https://doi.org/10.1097/HJH.0000000000001926
    • Sharif, S., Bots, M. L., Schalkwijk, C., Stehouwer, C. D. A., Visseren, F. L. J., Westerink, J., & SMART Study Grp (2018). Association between bone metabolism regulators and arterial stiffness in type 2 diabetes patients. Nutrition Metabolism and Cardiovascular Diseases, 28(12), 1245-1252. https://doi.org/10.1016/j.numecd.2018.06.004
    • Parmar, P., Lowry, E., Cugliari, G., Suderman, M., Wilson, R., Karhunen, V., Andrew, T., Wiklund, P., Wielscher, M., Guarrera, S., Teumer, A., Lehne, B., Milani, L., de Klein, N., Mishra, P. P., Melton, P. E., Mandaviya, P. R., Kasela, S., Nano, J., ... Sebert, S. (2018). Association of maternal prenatal smoking GFI1-locus and cardiometabolic phenotypes in 18,212 adults. EBioMedicine, 38, 206-216. https://doi.org/10.1016/j.ebiom.2018.10.066
    • 't Hart, L. M., Vogelzangs, N., Mook-Kanamori, D. O., Brahimaj, A., Nano, J., van der Heijden, A. A. W. A., van Dijk, K. W., Slieker, R. C., Steyerberg, E. W., Ikram, M. A., Beekman, M., Boomsma, D. I., van Duijn, C. M., Slagboom, P. E., Stehouwer, C. D. A., Schalkwijk, C. G., Arts, I. C. W., Dekker, J. M., Dehghan, A., ... van Greevenbroek, M. M. J. (2018). Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes. Journal of Clinical Endocrinology & Metabolism, 103(12), 4569-4579. https://doi.org/10.1210/jc.2018-01165
    • Xin, Y., Hertle, E., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2018). Complement C3 and C4, but not their regulators or activated products, are associated with incident metabolic syndrome: the CODAM study. Endocrine, 62(3), 617-627. https://doi.org/10.1007/s12020-018-1712-3
    • Van den Eynde, M. D. G., Geleijnse, J. M., Scheijen, J. L. J. M., Hanssen, N. M. J., Dower, J. I., Afman, L. A., Stehouwer, C. D. A., Hollman, P. C. H., & Schalkwijk, C. G. (2018). Quercetin, but Not Epicatechin, Decreases Plasma Concentrations of Methylglyoxal in Adults in a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial with Pure Flavonoids. Journal of Nutrition, 148(12), 1911-1916. https://doi.org/10.1093/jn/nxy236
    • de Waard, E. A. C., de Jong, J. J. A., Koster, A., Savelberg, H. H. C. M., van Geel, T. A., Houben, A. J. H. M., Schram, M. T., Dagnelie, P. C., van der Kallen, C. J., Sep, S. J. S., Stehouwer, C. D. A., Schaper, N. C., Berendschot, T. T. J. M., Schouten, J. S. A. G., Geusens, P. P. M. M., & van den Bergh, J. P. W. (2018). The association between diabetes status, HbA1c, diabetes duration, microvascular disease, and bone quality of the distal radius and tibia as measured with high-resolution peripheral quantitative computed tomography: The Maastricht Study. Osteoporosis International, 29(12), 2725-2738. https://doi.org/10.1007/s00198-018-4678-3
    • van der Velde, J. H. P. M., Schaper, N. C., Stehouwer, C. D. A., van der Kallen, C. J. H., Sep, S. J. S., Schram, M. T., Henry, R. M. A., Dagnelie, P. C., Eussen, S. J. P. M., van Dongen, M. C. J. M., Savelberg, H. H. C. M., & Koster, A. (2018). Which is more important for cardiometabolic health: sedentary time, higher intensity physical activity or cardiorespiratory fitness? The Maastricht Study. Diabetologia, 61(12), 2561-2569. https://doi.org/10.1007/s00125-018-4719-7
    • van Twist, D. J. L., Dinh, T., Bouwmans, E. M. E., & Kroon, A. A. (2018). Initial orthostatic hypotension among patients with unexplained syncope: An overlooked diagnosis?International Journal of Cardiology, 271, 269-273. https://doi.org/10.1016/j.ijcard.2018.05.043
    • van Sloten, T. T., Tafflet, M., Perier, M.-C., Dugravot, A., Climie, R. E. D., Singh-Manoux, A., & Empana, J.-P. (2018). Association of Change in Cardiovascular Risk Factors With Incident Cardiovascular Events. JAMA-Journal of the American Medical Association, 320(17), 1793-1804. https://doi.org/10.1001/jama.2018.16975
    • van Sloten, T. T., Boutouyrie, P., Lisan, Q., Tafflet, M., Thomas, F., Guibout, C., Climie, R. E., Pannier, B., Sharman, J. E., Laurent, S., Jouven, X., & Empana, J.-P. (2018). Body Silhouette Trajectories Across the Lifespan and Vascular Aging: The Paris Prospective Study 3. Hypertension, 72(5), 1095-1102. https://doi.org/10.1161/HYPERTENSIONAHA.118.11442
    • Gala, T. D. L. H., Herder, C., Rutters, F., Carstensen-Kirberg, M., Huth, C., Stehouwer, C. D. A., Nijpels, G., Schalkwijk, C., Flyvbjerg, A., Franks, P. W., Dekker, J., Meisinger, C., Koenig, W., Roden, M., Rathmann, W., Peters, A., Thorand, B., & IMI DIRECT Consortium (2018). Association of changes in inflammation with variation in glycaemia, insulin resistance and secretion based on the KORA study. Diabetes-metabolism Research and Reviews, 34(8), Article 3063. https://doi.org/10.1002/dmrr.3063
    • Bosma, H., Qi, Y., van Boxtel, M., Kohler, S., Schaper, N., Schram, M., Stehouwer, C., & Koster, A. (2018). Disentangling the higher risks of type 2 diabetes in lower educated people.European Journal of Public Health, 28, 50-51. https://doi.org/10.1093/eurpub/cky213.139