Publications
- 2020
- Schutten, M. T. J., Kusters, Y. H. A. M., Houben, A. J. H. M., Niessen, H. E., Roodt, J. O., Scheijen, J. L. J. M., van de Waardenburg, M. P., Schalkwijk, C. G., de Leeuw, P. W., & Stehouwer, C. D. A. (2020). Glucocorticoids affect metabolic but not muscle microvascular insulin sensitivity following high versus low salt intake. JCI INSIGHT, 5(6), Article 127530. https://doi.org/10.1172/jci.insight.127530
- Bot, M., Milaneschi, Y., Al-Shehri, T., Amin, N., Garmaeva, S., Onderwater, G. L. J., Pool, R., Thesing, C. S., Vijfhuizen, L. S., Vogelzangs, N., Arts, I. C. W., Demirkan, A., van Duijn, C., van Greevenbroek, M., van der Kallen, C. J. H., Koehler, S., Ligthart, L., van den Maagdenberg, M. J. M., Mook-Kanamori, D. O., ... BBMRI-NL Metabolomics Consortium (2020). Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls. Biological Psychiatry, 87(5), 409-418. https://doi.org/10.1016/j.biopsych.2019.08.016
- Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2020). Placental Mitochondrial Abnormalities Upon Hypoxia; The Cause of Placental Oxidative Stress?Reproductive Sciences, 27(SUPPL 1), 268A-268A.
- Nefs, G., Bazelmans, E., Donga, E., Tack, C. J., & de Galan, B. E. (2020). Sweet dreams or bitter nightmare: a narrative review of 25 years of research on the role of sleep in diabetes and the contributions of behavioural science. Diabetic Medicine, 37(3), 418-426. https://doi.org/10.1111/dme.14211
- Bellier, J., Nokin, M. J., Caprasse, M., Tiamiou, A., Blomme, A., Scheijen, J. L., Koopmansch, B., MacKay, G. M., Chiavarina, B., Costanza, B., Rademaker, G., Durieux, F., Agirman, F., Maloujahmoum, N., Cusumano, P. G., Lovinfosse, P., Leung, H. Y., Lambert, F., Bours, V., ... Bellahcene, A. (2020). Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab. Cell Reports, 30(5), 1400-1416.e6. https://doi.org/10.1016/j.celrep.2020.01.012
- van den Hombergh, E., de Rouw, N., van den Heuvel, M., Croes, S., Burger, D. M., Derijks, J., van Erp, N. P., & ter Heine, R. (2020). Simple and Rapid Quantification of the Multi-Enzyme Targeting Antifolate Pemetrexed in Human Plasma. Therapeutic Drug Monitoring, 42(1), 146-150. https://doi.org/10.1097/FTD.0000000000000672
- Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J.-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H., Franke, L., Heijmans, B. T., 't Hoen, P. A. C., van Meurs, J., Brooks, A., Penninx, B. W. J. H., Boomsma, D., Isaacs, A., Pool, R., ... BIOS Consortium (2020). A characterization of cis- and trans-heritability of RNA-Seq-based gene expression. European Journal of Human Genetics, 28(2), 253-263. https://doi.org/10.1038/s41431-019-0511-5
- van Dort, M. J., Driessen, J. H. M., Geusens, P., Romme, E. A. P. M., Smeenk, F. W. J. M., Rahel, B. M., Eisman, J. A., Wouters, E. F. M., & van den Bergh, J. P. W. (2020). Association between vertebral fractures and coronary artery calcification in current and former smokers in the ECLIPSE cohort. Osteoporosis International, 31(2), 297-305. https://doi.org/10.1007/s00198-019-05218-w
- Willemse, J. P. M. M., Meertens, L. J. E., Scheepers, H. C. J., Achten, N. M. J., Eussen, S. J., van Dongen, M. C., & Smits, L. J. M. (2020). Calcium intake from diet and supplement use during early pregnancy: the Expect study I. European Journal of Nutrition, 59(1), 167-174. https://doi.org/10.1007/s00394-019-01896-8
- Oshagbemi, O. A., Franssen, F. M. E., Wouters, E. F. M., Maitland-van der Zee, A. H., Driessen, J. H. M., de Boer, A., & de Vries, F. (2020). C-reactive protein as a biomarker of response to inhaled corticosteroids among patients with COPD. Pulmonary Pharmacology & Therapeutics, 60, Article 101870. https://doi.org/10.1016/j.pupt.2019.101870
- Koole, J. L., Bours, M. J. L., Breedveld-Peters, J. J. L., van Roekel, E. H., van Dongen, M. C. J. M., Eussen, S. J. P. M., van Zutphen, M., van Duijnhoven, F. J. B., Boshuizen, H. C., & Weijenberg, M. P. (2020). Evaluating the Validity of a Food Frequency Questionnaire in Comparison with a 7-Day Dietary Record for Measuring Dietary Intake in a Population of Survivors of Colorectal Cancer. Journal of the Academy of Nutrition and Dietetics, 120(2), 245-257. https://doi.org/10.1016/j.jand.2019.09.008
- Brouwers, M. C. G. J., Simons, N., Stehouwer, C. D. A., & Isaacs, A. (2020). Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality. Diabetologia, 63(2), 253-260. https://doi.org/10.1007/s00125-019-05024-3
- de Ruijter, T. C., van der Heide, F., Smits, K. M., Aarts, M. J., van Engeland, M., & Heijnen, V. C. G. (2020). Prognostic DNA methylation markers for hormone receptor breast cancer: a systematic review. Breast Cancer Research, 22(1), Article 13. https://doi.org/10.1186/s13058-020-1250-9
- Hagenbeek, F. A., Pool, R., van Dongen, J., Draisma, H. H. M., Jan Hottenga, J., Willemsen, G., Abdellaoui, A., Fedko, I. O., den Braber, A., Visser, P. J., de Geus, E. J. C. N., Willems van Dijk, K., Verhoeven, A., Suchiman, H. E., Beekman, M., Slagboom, P. E., van Duijn, C. M., Harms, A. C., Hankemeier, T., ... BBMRI Metabolomics Consortium (2020). Heritability estimates for 361 blood metabolites across 40 genome-wide association studies. Nature Communications, 11(1), Article 39. https://doi.org/10.1038/s41467-019-13770-6
- de Ritter, R., de Jong, M., Vos, R. C., van der Kallen, C. J. H., Sep, S. J. S., Woodward, M., Stehouwer, C. D. A., Bots, M. L., & Peters, S. A. E. (2020). Sex differences in the risk of vascular disease associated with diabetes. Biology of Sex Differences, 11(1), Article 1. https://doi.org/10.1186/s13293-019-0277-z
- Liu, J., Lahousse, L., Nivard, M. G., Bot, M., Chen, L. M., van Klinken, J. B., Thesing, C. S., Beekman, M., van den Akker, E. B., Slieker, R. C., Waterham, E., van der Kallen, C. J. H., de Boer, I., Li-Gao, R. F., Vojinovic, D., Amin, N., Radjabzadeh, D., Kraaij, R., Alferink, L. J. M., ... van Duijn, C. M. (2020). Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas. Nature Medicine, 26(1), 110-117. https://doi.org/10.1038/s41591-019-0722-x
- Nielen, J. T. H., Driessen, J. H. M., Dagnelie, P. C., Boonen, A., van den Bemt, B., van Onzenoort, H. A. W., Neef, C., Henry, R. M. A., Burden, A. M., Sep, S. J. S., van der Kallen, C. J., Schram, M. T., Schaper, N., Stehouwer, C. D. A., Smits, L., & de Vries, F. (2020). Drug utilization in the Maastricht Study: A comparison with nationwide data. Medicine, 99(1), Article 18524. https://doi.org/10.1097/MD.0000000000018524
- van Meijel, L. A., de Vegt, F., Abbink, E. J., Rutters, F., Schram, M. T., van der Klauw, M. M., Wolffenbuttel, B. H. R., Siegelaar, S., DeVries, J. H., Sijbrands, E. J. G., Ozcan, B., de Valk, H. W., Silvius, B., Schaper, N., Stehouwer, C. D. A., Elders, P. J. M., Tack, C. J., & de Galan, B. E. (2020). High prevalence of impaired awareness of hypoglycemia and severe hypoglycemia among people with insulin-treated type 2 diabetes: The Dutch Diabetes Pearl Cohort. BMJ Open Diabetes Research & Care, 8(1), Article 000935. https://doi.org/10.1136/bmjdrc-2019-000935
- Brouwers, M. C. G. J., de Graaf, J., Simons, N., Meex, S., ten Doeschate, S., van Heertum, S., Heidemann, B., Luijten, J., de Boer, D., Schaper, N., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2020). Incidence of type 2 diabetes in familial combined hyperlipidemia. BMJ Open Diabetes Research & Care, 8(1), Article 001107. https://doi.org/10.1136/bmjdrc-2019-001107
- Schalkwijk, C. G., & Stehouwer, C. D. A. (2020). METHYLGLYOXAL, A HIGHLY REACTIVE DICARBONYL COMPOUND, IN DIABETES, ITS VASCULAR COMPLICATIONS, AND OTHER AGE-RELATED DISEASES. Physiological Reviews, 100(1), 407-461. https://doi.org/10.1152/physrev.00001.2019
- Rensma, S. P., van Sloten, T. T., Houben, A. J. H. M., Koehler, S., van Boxtel, M. P. J., Berendschot, T. T. J. M., Jansen, J. F. A., Verhey, F. R. J., Kroon, A. A., Koster, A., Backes, W. H., Schaper, N., Dinant, G.-J., Schalkwijk, C. G., Henry, R. M. A., Wolfs, E. M. L., van Heumen, M. J. A., Schram, M. T., & Stehouwer, C. D. A. (2020). Microvascular Dysfunction Is Associated With Worse Cognitive Performance The Maastricht Study. Hypertension, 75(1), 237-245. https://doi.org/10.1161/hypertensionaha.119.13023
- Vossen, L. M., Kroon, A. A., Schurgers, L. J., & de Leeuw, P. W. (2020). Pharmacological and Nutritional Modulation of Vascular Calcification. Nutrients, 12(1), Article 100. https://doi.org/10.3390/nu12010100
- Vergoossen, L. W., Schram, M. T., de Jong, J. J., Stehouwer, C. D., Schaper, N. C., Henry, R. M., van der Kallen, C. J., Dagnelie, P. C., van Boxtel, M. P., Eussen, S. J., Backes, W. H., & Jansen, J. F. (2020). White Matter Connectivity Abnormalities in Prediabetes and Type 2 Diabetes: The Maastricht Study. Diabetes Care, 43(1), 201-208. https://doi.org/10.2337/dc19-0762
- Wetzels - van Hooijdonk, S., Bijnen, M., Wijnands, E., van de Gaar, M. J., Tan, A., Coort, S., Biessen, E., Schalkwijk, C., & Wouters, K. (2020). CD11c−MHC2low Macrophages Are a New Inflammatory and Dynamic Subset in Murine Adipose Tissue. Immunometabolism, 2(2), Article e200015. https://doi.org/10.20900/immunometab20200015
- Abbas, H., Kurdi, M., de Vries, F., van Onzenoort, H. A. W., Driessen, J. H. M., Watfa, M., & Karam, R. (2020). Factors Associated with Antihypertensive Medication Non-Adherence: A Cross-Sectional Study Among Lebanese Hypertensive Adults. Patient Preference and Adherence, 14, 663-673. https://doi.org/10.2147/PPA.S238751
- Josefs, T., Wouters, K., Tietge, U. J. F., Annema, W., Dullaart, R. P. F., Vaisar, T., Arts, I. C. W., van der Kallen, C. J. H., Stehouwer, C. D. A., Schalkwijk, C. G., Goldberg, I. J., Fisher, E. A., & van Greevenbroek, M. M. J. (2020). High-density lipoprotein cholesterol efflux capacity is not associated with atherosclerosis and prevalence of cardiovascular outcome: The CODAM study. Journal of Clinical Lipidology, 14(1), 122-132.e4. https://doi.org/10.1016/j.jacl.2019.10.012
- 2019
- van der Kolk, B. W., Kalafati, M., Adriaens, M., van Greevenbroek, M. M. J., Vogelzangs, N., Saris, W. H. M., Astrup, A., Valsesia, A., Langin, D., van der Kallen, C. J. H., Eussen, S. J. P. M., Schalkwijk, C. G., Stehouwer, C. D. A., Goossens, G. H., Arts, I. C. W., Jocken, J. W. E., Evelo, C. T., & Blaak, E. E. (2019). Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans. Diabetes, 68(12), 2247-2258. https://doi.org/10.2337/db19-0560
- Foreman, Y. D., Brouwers, M. C. G. J., Berendschot, T. T. J. M., van Dongen, M. C. J. M., Eussen, S. J. P. M., van Greevenbroek, M. M. J., Henry, R. M. A., Houben, A. J. H. M., van der Kallen, C. J. H., Kroon, A. A., Reesink, K. D., Schram, M. T., Schaper, N. C., & Stehouwer, C. D. A. (2019). The oral glucose tolerance test-derived incremental glucose peak is associated with greater arterial stiffness and maladaptive arterial remodeling: The Maastricht Study. Cardiovascular Diabetology, 18(1), Article 152. https://doi.org/10.1186/s12933-019-0950-x
- Ginsberg, C., Houben, A. J. H. M., Malhotra, R., Berendschot, T. T. J. M., Dagnelie, P. C., Kooman, J. P., Webers, C. A., Stehouwer, C. D. A., & Ix, J. H. (2019). Serum Phosphate and Microvascular Function in a Population-Based Cohort. Clinical journal of the American Society of Nephrology, 14(11), 1626-1633. https://doi.org/10.2215/CJN.02610319
- den Heijer, C. D. J., Hoebe, C. J. P. A., Driessen, J. H. M., Wolffs, P., van den Broek, I. V. F., Hoenderboom, B. M., Williams, R., de Vries, F., & Dukers-Muijrers, N. H. T. M. (2019). Chlamydia trachomatis and the Risk of Pelvic Inflammatory Disease, Ectopic Pregnancy, and Female Infertility: A Retrospective Cohort Study Among Primary Care Patients. Clinical Infectious Diseases, 69(9), 1517-1525. https://doi.org/10.1093/cid/ciz429
- Harvey, B. M., Eussen, S. R. B. M., van Helvoort, A., & Harthoorn, L. F. (2019). Cow's Milk Allergic Infants on Elemental Formula Maintain Adequate Mineral Status Despite Using Acid-suppressive Drugs. Journal of Pediatric Gastroenterology and Nutrition, 69(5), E147-E148. https://doi.org/10.1097/MPG.0000000000002469
- Simons, N., Debray, F.-G., Schaper, N. C., Kooi, M. E., Feskens, E. J. M., Hollak, C. E. M., Lindeboom, L., Koek, G. H., Bons, J. A. P., Lefeber, D. J., Hodson, L., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D., & Brouwers, M. C. G. J. (2019). Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content. Journal of Clinical Endocrinology & Metabolism, 104(11), 5056-5064. https://doi.org/10.1210/jc.2018-02795
- Abtahi, S., Driessen, J. H. M., Vestergaard, P., van den Bergh, J., Boonen, A., de Vries, F., & Burden, A. M. (2019). Secular trends in major osteoporotic fractures among 50+ adults in Denmark between 1995 and 2010. Osteoporosis International, 30(11), 2217-2223. https://doi.org/10.1007/s00198-019-05109-0
- Jaminon, A., Reesink, K., Kroon, A., & Schurgers, L. (2019). The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes. International journal of molecular sciences, 20(22), Article 5694. https://doi.org/10.3390/ijms20225694
- Maas, S. C. E., Vidaki, A., Wilson, R., Teumer, A., Liu, F., van Meurs, J. B. J., Uitterlinden, A. G., Boomsma, D. I., de Geus, E. J. C., Willemsen, G., van Dongen, J., van der Kallen, C. J. H., Slagboom, P. E., Beekman, M., van Heemst, D., van den Berg, L. H., Duijts, L., Jaddoe, V. W. V., Ladwig, K.-H., ... BIOS Consortium (2019). Validated inference of smoking habits from blood with a finite DNA methylation marker set. European Journal of Epidemiology, 34(11), 1055-1074. https://doi.org/10.1007/s10654-019-00555-w
- van Dongen, J., Zilhao, N. R., Sugden, K., Hannon, E. J., Mill, J., Caspi, A., Agnew-Blais, J., Arseneault, L., Corcoran, D. L., Moffitt, T. E., Poulton, R., Franke, B., Boomsma, D., Heijmans, B. T., t'Hoen, P. A. G., van Meurs, J., Isaacs, A., Jansen, R., Franke, L., ... BIOS Consortium (2019). Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults. Biological Psychiatry, 86(8), 599-607. https://doi.org/10.1016/j.biopsych.2019.02.016
- Sotomayor, C. G., Gomes-Neto, A. W., van Londen, M., Gans, R. O. B., Nolte, I. M., Berger, S. P., Navis, G. J., Rodrigo, R., Leuvenink, H. G. D., Schalkwijk, C. G., & Bakker, S. J. L. (2019). Circulating Advanced Glycation Endproducts and Long-Term Risk of Cardiovascular Mortality in Kidney Transplant Recipients. Clinical journal of the American Society of Nephrology, 14(10), 1512-1520. https://doi.org/10.2215/CJN.00540119
- Latten, G. H. P., Spek, M., Muris, J. W. M., Cals, J. W. L., & Stassen, P. M. (2019). Accuracy and interobserver-agreement of respiratory rate measurements by healthcare professionals, and its effect on the outcomes of clinical prediction/diagnostic rules. PLOS ONE, 14(10), e0223155. Article 0223155. https://doi.org/10.1371/journal.pone.0223155
- de Ritter, R., Sep, S. J. S., van der Kallen, C. J. H., Schram, M. T., Koster, A., Kroon, A. A., van Greevenbroek, M. M. J., Eussen, S. J. P. M., Dagnelie, P. C., de Jong, M., Vos, R. C., Woodward, M., Bots, M. L., Peters, S. A. E., & Stehouwer, C. D. A. (2019). Adverse differences in cardiometabolic risk factor levels between individuals with pre-diabetes and normal glucose metabolism are more pronounced in women than in men: the Maastricht Study. BMJ Open Diabetes Research & Care, 7(1), Article 000787. https://doi.org/10.1136/bmjdrc-2019-000787
- Denissen, K. F. M., Boonen, A., Nielen, J. T. H., Feitsma, A. L., van den Heuvel, E. G. H. M., Emans, P. J., Stehouwer, C. D. A., Sep, S. J. S., van Dongen, M. C. J. M., Dagnelie, P. C., & Eussen, S. J. P. M. (2019). Consumption of dairy products in relation to the presence of clinical knee osteoarthritis: The Maastricht Study. European Journal of Nutrition, 58(7), 2693-2704. https://doi.org/10.1007/s00394-018-1818-7
- Gennip, A. C. E. V., Broers, N. J. H., Meulen, K. J. T., Canaud, B., Christiaans, M. H. L., Cornelis, T., Gelens, M. A. C. J., Hermans, M. M. H., Konings, C. J. A. M., Net, J. B. V. D., Sande, F. M. V. D., Schalkwijk, C. G., Stifft, F., Wirtz, J. J. J. M., Kooman, J. P., & Martens, R. J. H. (2019). Endothelial dysfunction and low-grade inflammation in the transition to renal replacement therapy. PLOS ONE, 14(9), Article e0222547. https://doi.org/10.1371/journal.pone.0222547
- Wijma, R. A., Hoogtanders, K. E. J., Croes, S., Mouton, J. W., & Bruggemann, R. J. M. (2019). Development and validation of a fast and sensitive UHPLC-DAD assay for the quantification of nitrofurantoin in plasma and urine. Journal of Pharmaceutical and Biomedical Analysis, 174, 161-167. https://doi.org/10.1016/j.jpba.2019.05.054
- Ahluwalia, T. S., Tofte, N., Vogelzangs, N., Mook-Kanamori, D., Brahimaj, A., Frimodt-Moller, M., Arts, I., Beulens, J., van der Heijden, A., Stehouwer, C., Nijpels, G., van Greevenbroek, M., van der Kallen, C., Rossing, P., & 't Hart, L. M. (2019). Plasma metabolomics identifies markers of kidney function in 3,064 Europeans with type 2 diabetes. Diabetologia, 62, S456-S456.
- Vranken, L., Wyers, C. E., van Rietbergen, B., Driessen, J. H. M., Geusens, P. P. M. M., Janzing, H. M. J., van der Velde, R. Y., & van den Bergh, J. P. W. (2019). The association between prevalent vertebral fractures and bone quality of the distal radius and distal tibia as measured with HR-pQCT in postmenopausal women with a recent non-vertebral fracture at the Fracture Liaison Service. Osteoporosis International, 30(9), 1789-1797. https://doi.org/10.1007/s00198-019-05081-9
- van Maren, M. A., Wyers, C. E., Driessen, J. H. M., Visser, J. V., de Vries, F., van de Wijdeven, K., Gevers, S., Lems, W. F., Emmelot-Vonk, M. H., & van den Bergh, J. P. W. (2019). Two-year persistence with teriparatide improved significantly after introduction of an educational and motivational support program. Osteoporosis International, 30(9), 1837-1844. https://doi.org/10.1007/s00198-019-05052-0
- Sun, C., Ippel, L., van Soest, J., Wouters, B., Malic, A., Adekunle, O., van den Berg, B., Mussmann, O., Koster, A., van der Kallen, C., van Oppen, C., Townend, D., Dekker, A., & Dumontier, M. (2019). A Privacy-Preserving Infrastructure for Analyzing Personal Health Data in a Vertically Partitioned Scenario. Studies in Health Technology and Informatics, 264, 373-377. https://doi.org/10.3233/SHTI190246




