• 2014
    • van der Linden, N., Klinkenberg, L. J. J., Meex, S. J. R., Beckers, E. A. M., de Wit, N. C. J., & Prinzen, L. (2014). Immature platelet fraction measured on the Sysmex XN hemocytometer predicts thrombopoietic recovery after autologous stem cell transplantation. European Journal of Haematology, 93(2), 150-156. https://doi.org/10.1111/ejh.12319
    • Ninivaggi, M., Kelchtermans, H., Kuijpers, M. J., Hemmeryckx, B., Heemskerk, J. W. M., Lindhout, T., Hoylaerts, M. F., & de Laat, B. (2014). Whole blood thrombin generation in Bmal1-deficient mice. Thrombosis and Haemostasis, 112(2), 271-275. https://doi.org/10.1160/TH13-11-0910
    • Wildhagen, K. C. A. A., Schrijver, R., Beckers, L., ten Cate, H., Reutelingsperger, C. P. M., Lutgens, E., & Nicolaes, G. A. F. (2014). Effects of Exogenous Recombinant APC in Mouse Models of Ischemia Reperfusion Injury and of Atherosclerosis. PLOS ONE, 9(7), Article e101446. https://doi.org/10.1371/journal.pone.0101446
    • Angin, Y., Schwenk, R. W., Nergiz-Unal, R., Hoebers, N., Heemskerk, J. W. M., Kuijpers, M. J., Coumans, W. A., van Zandvoort, M. A. M. J., Bonen, A., Neumann, D., Glatz, J. F. C., & Luiken, J. (2014). Calcium signaling recruits substrate transporters GLUT4 and CD36 to the sarcolemma without increasing cardiac substrate uptake. American Journal of Physiology : Endocrinology and Metabolism, 307(2), E225-E236. https://doi.org/10.1152/ajpendo.00655.2013
    • de Witt, S. M., Swieringa, F., Cavill, R., Lamers, M. M., van Kruchten, R., Mastenbroek, T., Baaten, C., Coort, S., Pugh, N., Schulz, A., Scharrer, I., Jurk, K., Zieger, B., Clemetson, K. J., Farndale, R. W., Heemskerk, J. W., & Cosemans, J. M. (2014). Identification of platelet function defects by multi-parameter assessment of thrombus formation. Nature Communications, 5, Article 4257. https://doi.org/10.1038/ncomms5257
    • Schmitt, M. M. N., Fraemohs, L., Hackeng, T. M., Weber, C., & Koenen, R. R. (2014). Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-A redistribution. Atherosclerosis, 234(2), 254-264. https://doi.org/10.1016/j.atherosclerosis.2014.03.014
    • Streng, A. S., Jacobs, L. H. J., Schwenk, R. W., Cardinaels, E. P. M., Meex, S. J. R., Glatz, J. F. C., Wodzig, W. K. W. H., & van Dieijen-Visser, M. P. (2014). Cardiac troponin in ischemic cardiomyocytes: Intracellular decrease before onset of cell death. Experimental and Molecular Pathology, 96(3), 339-345. https://doi.org/10.1016/j.yexmp.2014.02.012
    • Nagler, M., ten Cate, H., Kathriner, S., Casutt, M., Bachmann, L. M., & Wuillemin, W. A. (2014). Consistency of thromboelastometry analysis under scrutiny: Results of a systematic evaluation within and between analysers. Thrombosis and Haemostasis, 111(6), 1161-1166. https://doi.org/10.1160/TH13-10-0870
    • Sperandio, O., Wildhagen, K. C. A. A., Schrijver, R., Wielders, S., Villoutreix, B. O., & Nicolaes, G. A. F. (2014). Identification of novel small molecule inhibitors of activated protein C. Thrombosis Research, 133(6), 1105-1114. https://doi.org/10.1016/j.thromres.2014.01.026
    • Shadid, N. H., van der Velden, S. K., van Oerle, R., ten Cate, H., Sommer, A., & Nelemans, P. (2014). In vivo effects of foam sclerotherapy on coagulation. Phlebology: The Journal of Venous Disease, 29(5), 287-292. https://doi.org/10.1177/0268355513479590
    • Posthuma, J. J., Loeffen, R., van Oerle, R., Henskens, Y. M. C., ten Cate, H., Spronk, H. M. H., & van der Meijden, P. E. J. (2014). Long-term strenuous exercise induces a hypercoagulable state through contact activation. Thrombosis and Haemostasis, 111(6), 1197-1199. https://doi.org/10.1160/TH13-11-0963
    • Kuijpers, M. J. E., de Witt, S., Nergiz-Unal, R., van Kruchten, R., Korporaal, S. J. A., Verhamme, P., Febbraio, M., Tjwa, M., Voshol, P. J., Hoylaerts, M. F., Cosemans, J. M. E. M., & Heemskerk, J. W. M. (2014). Supporting Roles of Platelet Thrombospondin-1 and CD36 in Thrombus Formation on Collagen. Arteriosclerosis Thrombosis and Vascular Biology, 34(6), 1187-1192. https://doi.org/10.1161/ATVBAHA.113.302917
    • Projahn, D., Simsekyilmaz, S., Singh, S., Kanzler, I., Kramp, B. K., Langer, M., Burlacu, A., Bernhagen, J., Klee, D., Zernecke, A., Hackeng, T. M., Groll, J., Weber, C., Liehn, E. A., & Koenen, R. R. (2014). Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction. Journal of Cellular and Molecular Medicine, 18(5), 790-800. https://doi.org/10.1111/jcmm.12225
    • Spronk, H. M. H., ten Cate, H., & van der Meijden, P. E. J. (2014). Differential roles of Tissue Factor and Phosphatidylserine in activation of coagulation. Thrombosis Research, 133, S54-S56. https://doi.org/10.1016/j.thromres.2014.03.022
    • de Witt, S. M., Verdoold, R., Cosemans, J. M. E. M., & Heemskerk, J. W. M. (2014). Insights into platelet-based control of coagulation. Thrombosis Research, 133, S139-S148. https://doi.org/10.1016/S0049-3848(14)50024-2
    • ten Cate, H., & Meade, T. (2014). The Northwick Park Heart Study: evidence from the laboratory. Journal of Thrombosis and Haemostasis, 12(5), 587-592. https://doi.org/10.1111/jth.12545
    • Castoldi, E. (2014). FV and APC resistance: the plot thickens. Blood, 123(15), 2288-2289. https://doi.org/10.1182/blood-2014-02-557363
    • Vlassaks, E., Nikiforou, M., Strackx, E., Hutten, M., Bekers, O., Gazzolo, D., Li Volti, G., Martinez-Martinez, P., Kramer, B. W., & Gavilanes, A. W. (2014). Acute and chronic immunomodulatory changes in rat liver after fetal and perinatal asphyxia. Journal of developmental origins of health and disease, 5(2), 98-108. https://doi.org/10.1017/S2040174413000561
    • Koenen, R. R. (2014). CX(3)CL1, a special deputy at the intersection of platelets and the vessel wall. Thrombosis and Haemostasis, 111(4), 567-567. https://doi.org/10.1160/TH14-02-0173
    • Kok, M., Mihl, C., Mingels, A. A., Kietselaer, B. L., Muhlenbruch, G., Seehofnerova, A., Wildberger, J. E., & Das, M. (2014). Influence of Contrast Media Viscosity and Temperature on Injection Pressure in Computed Tomographic Angiography A Phantom Study. Investigative Radiology, 49(4), 217-223. https://doi.org/10.1097/RLI.0000000000000019
    • Eijgenraam, P., ten Cate, H., & ten Cate-Hoek, A. J. (2014). Practice of bridging anticoagulation: guideline adherence and risk factors for bleeding. Netherlands Journal of Medicine, 72(3), 157-164.
    • Olde Engberink, R. H. G., Kuiper, G. J. A. J. M., Wetzels, R. J. H., Nelemans, P. J., Lance, M. D., Beckers, E. A. M., & Henskens, Y. M. C. (2014). Rapid and Correct Prediction of Thrombocytopenia and Hypofibrinogenemia With Rotational Thromboelastometry in Cardiac Surgery. Journal of Cardiothoracic and Vascular Anesthesia, 28(2), 210-216. https://doi.org/10.1053/j.jvca.2013.12.004
    • Raps, M., Curvers, J., Helmerhorst, F. M., Ballieux, B. E. P. B., Rosing, J., Thomassen, S., Rosendaal, F. R., & van Vliet, H. A. A. M. (2014). Thyroid function, activated protein C resistance and the risk of venous thrombosis in users of hormonal contraceptives. Thrombosis Research, 133(4), 640-644. https://doi.org/10.1016/j.thromres.2013.12.041
    • Chatzigeorgiou, A., Seijkens, T., Zarzycka, B., Engel, D., Poggi, M., van den Berg, S., van den Berg, S., Soehnlein, O., Winkels, H., Beckers, L., Lievens, D., Driessen, A., Kusters, P., Biessen, E., Garcia-Martin, R., Klotzsche-von Ameln, A., Gijbels, M., Noelle, R., Boon, L., ... Lutgens, E. (2014). Correction for Chatzigeorgiou et al., Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance (vol 111, pg 2686, 2014). Proceedings of the National Academy of Sciences of the United States of America, 111(12), 4644-4644. https://doi.org/10.1073/pnas.1403231111
    • Li, X., Zhu, M., Penfold, M. E., Koenen, R. R., Thiemann, A., Heyll, K., Akhtar, S., Koyadan, S., Wu, Z., Gremse, F., Kiessling, F., van Zandvoort, M., Schall, T. J., Weber, C., & Schober, A. (2014). Activation of CXCR7 Limits Atherosclerosis and Improves Hyperlipidemia by Increasing Cholesterol Uptake in Adipose Tissue. Circulation, 129(11), 1244-1253. https://doi.org/10.1161/CIRCULATIONAHA.113.006840
    • Geersing, G. J., Zuithoff, N. P. A., Kearon, C., Anderson, D. R., ten Cate-Hoek, A. J., Elf, J. L., Bates, S. M., Hoes, A. W., Kraaijenhagen, R. A., Oudega, R., Schutgens, R. E. G., Stevens, S. M., Woller, S. C., Wells, P. S., & Moons, K. G. M. (2014). Exclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual patient data meta-analysis. BMJ, 348, Article g1340. https://doi.org/10.1136/bmj.g1340
    • Hoek - ten Cate, A. (2014). Elastic compression stockings-is there any benefit?Lancet, 383(9920), 851-853. https://doi.org/10.1016/S0140-6736(13)62347-8
    • Tragante, V., Barnes, M. R., Ganesh, S. K., Lanktree, M. B., Guo, W., Franceschini, N., Smith, E. N., Johnson, T., Holmes, M. V., Padmanabhan, S., Karczewski, K. J., Almoguera, B., Barnard, J., Baumert, J., Chang, Y.-P. C., Elbers, C. C., Farrall, M., Fischer, M. E., Gaunt, T. R., ... Keating, B. J. (2014). Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics, 94(3), 349-60. https://doi.org/10.1016/j.ajhg.2013.12.016
    • Geenen, I. L., Verbruggen, S., Molin, D. G., Spronk, H. M., Maessen, J. G., Meesters, B., Schurink, G. W., & Post, M. J. (2014). Phenotypic Fitness of Primary Endothelial Cells Cultured from Patients with High Cardiovascular Risk or Chronic Kidney Disease for Vascular Tissue Engineering. Tissue Engineering, 20(5-6), 1049-1059. https://doi.org/10.1089/ten.tea.2013.0163
    • Spronk, H. M. H., de Jong, A. M., Crijns, H. J., Schotten, U., Van Gelder, I. C., & ten Cate, H. (2014). Pleiotropic effects of factor Xa and thrombin: what to expect from novel anticoagulants. Cardiovascular Research, 101(3), 344-351. https://doi.org/10.1093/cvr/cvt343
    • Ninivaggi, M., Feijge, M. A. H., Baaten, C. C. F. M. J., Kuiper, G. J. A. J. M., Marcus, M. A. E., ten Cate, H., Lance, M. D., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2014). Additive roles of platelets and fibrinogen in whole-blood fibrin clot formation upon dilution as assessed by thromboelastometry. Thrombosis and Haemostasis, 111(3), 447-457. https://doi.org/10.1160/TH13-06-0493
    • Segers, O., Simioni, P., Tormene, D., & Castoldi, E. (2014). Influence of single nucleotide polymorphisms on thrombin generation in factor V Leiden heterozygotes. Thrombosis and Haemostasis, 111(3), 438-446. https://doi.org/10.1160/TH13-05-0360
    • Bosch, Y. P. J., al Dieri, R., ten Cate, H., Nelemans, P. J., Bloemen, S., de Laat, B., Hemker, C., Weerwind, P. W., Maessen, J. G., & Mochtar, B. (2014). Measurement of thrombin generation intra-operatively and its association with bleeding tendency after cardiac surgery. Thrombosis Research, 133(3), 488-494. https://doi.org/10.1016/j.thromres.2013.12.017
    • Pop, A. S., Levenga, J., de Esch, C. E. F., Buijsen, R. A. M., Nieuwenhuizen, I. M., Li, T., Isaacs, A., Gasparini, F., Oostra, B. A., & Willemsen, R. (2014). Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant. Psychopharmacology, 231(6), 1227-35. https://doi.org/10.1007/s00213-012-2947-y
    • Kamphuisen, P. W., & ten Cate, H. (2014). Cardiovascular risk in patients with hemophilia. Blood, 123(9), 1297-1301. https://doi.org/10.1182/blood-2013-11-453159
    • Karagoz, G. E., Duarte, A. M. S., Akoury, E., Ippel, H., Biernat, J., Luengo, T. M., Radli, M., Didenko, T., Nordhues, B. A., Veprintsev, D. B., Dickey, C. A., Mandelkow, E., Zweckstetter, M., Boelens, R., Madl, T., & Rudiger, S. G. D. (2014). Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action. Cell, 156(5), 963-974. https://doi.org/10.1016/j.cell.2014.01.037
    • Chatzigeorgioua, A., Seijkens, T., Zarzycka, B., Engel, D., Poggi, M., van den Berg, S., van den Berg, S., Soehnlein, O., Winkels, H., Beckers, L., Lievens, D., Driessen, A., Kusters, P., Biessen, E., Garcia-Martin, R., Ameln, A. K., Gijbels, M., Noelle, R., Boon, L., ... Lutgens, E. (2014). Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance. Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2686-2691. https://doi.org/10.1073/pnas.1400419111
    • Wildhagen, K. C. A. A., Garcia de Frutos, P., Reutelingsperger, C. P., Schrijver, R., Areste, C., Ortega-Gomez, A., Deckers, N. M., Hemker, H. C., Soehnlein, O., & Nicolaes, G. A. F. (2014). Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis. Blood, 123(7), 1098-1101. https://doi.org/10.1182/blood-2013-07-514984
    • Peloso, G. M., Auer, P. L., Bis, J. C., Voorman, A., Morrison, A. C., Stitziel, N. O., Brody, J. A., Khetarpal, S. A., Crosby, J. R., Fornage, M., Isaacs, A., Jakobsdottir, J., Feitosa, M. F., Davies, G., Huffman, J. E., Manichaikul, A., Davis, B., Lohman, K., Joon, A. Y., ... Cupples, L. A. (2014). Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. American Journal of Human Genetics, 94(2), 223-32. https://doi.org/10.1016/j.ajhg.2014.01.009
    • Lange, L. A., Hu, Y., Zhang, H., Xue, C., Schmidt, E. M., Tang, Z.-Z., Bizon, C., Lange, E. M., Smith, J. D., Turner, E. H., Jun, G., Kang, H. M., Peloso, G., Auer, P., Li, K.-P., Flannick, J., Zhang, J., Fuchsberger, C., Gaulton, K., ... NHLBI Grand Opportunity Exome Sequencing Project (2014). Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics, 94(2), 233-45. https://doi.org/10.1016/j.ajhg.2014.01.010
    • Tilstam, P. V., Gijbels, M. J., Habbeddine, M., Cudejko, C., Asare, Y., Theelen, W., Zhou, B., Doering, Y., Drechsler, M., Pawig, L., Simsekyilmaz, S., Koenen, R. R., de Winther, M. P. J., Lawrence, T., Bernhagen, J., Zernecke, A., Weber, C., & Noels, H. (2014). Bone Marrow-Specific Knock-In of a Non-Activatable Ikk alpha Kinase Mutant Influences Haematopoiesis but Not Atherosclerosis in Apoe-Deficient Mice. PLOS ONE, 9(2), Article e87452. https://doi.org/10.1371/journal.pone.0087452
    • Avery, C. L., Sitlani, C. M., Arking, D. E., Arnett, D. K., Bis, J. C., Boerwinkle, E., Buckley, B. M., Ida Chen, Y.-D., de Craen, A. J. M., Eijgelsheim, M., Enquobahrie, D., Evans, D. S., Ford, I., Garcia, M. E., Gudnason, V., Harris, T. B., Heckbert, S. R., Hochner, H., Hofman, A., ... Psaty, B. M. (2014). Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. Pharmacogenomics Journal, 14(1), 6-13. https://doi.org/10.1038/tpj.2013.4
    • Jaczewska, J., Abdulreda, M. H., Yau, C. Y., Schmitt, M. M., Schubert, I., Berggren, P.-O., Weber, C., Koenen, R. R., Moy, V. T., & Wojcikiewicz, E. P. (2014). TNF-alpha and IFN-gamma promote lymphocyte adhesion to endothelial junctional regions facilitating transendothelial migration. Journal of Leukocyte Biology, 95(2), 265-274. https://doi.org/10.1189/jlb.0412205
    • Vaidya, A., Joore, M. A., Hoek - ten Cate, A. J., ten Cate, H., & Severens, J. L. (2014). Screen or not to screen for peripheral arterial disease: guidance from a decision model. BMC Public Health, 14(1), Article 89. https://doi.org/10.1186/1471-2458-14-89
    • Dockal, M., Hartmann, R., Fries, M., Thomassen, M. C. L. G. D., Heinzmann, A., Ehrlich, H., Rosing, J., Osterkamp, F., Polakowski, T., Reineke, U., Griessner, A., Brandstetter, H., & Scheiflinger, F. (2014). Small Peptides Blocking Inhibition of Factor Xa and Tissue Factor-Factor VIIa by Tissue Factor Pathway Inhibitor (TFPI). Journal of Biological Chemistry, 289(3), 1732-1741. https://doi.org/10.1074/jbc.M113.533836
    • Schmitt, M. M. N., Megens, R. T. A., Zernecke, A., Bidzhekov, K., van den Akker, N. M., Rademakers, T., van Zandvoort, M. A., Hackeng, T. M., Koenen, R. R., & Weber, C. (2014). Endothelial Junctional Adhesion Molecule-A Guides Monocytes Into Flow-Dependent Predilection Sites of Atherosclerosis. Circulation, 129(1), 66–76. https://doi.org/10.1161/CIRCULATIONAHA.113.004149
    • Berbis, M. A., Andre, S., Canada, F. J., Pipkorn, R., Ippel, H., Mayo, K. H., Kuebler, D., Gabius, H.-J., & Jimenez-Barbero, J. (2014). Peptides derived from human galectin-3 N-terminal tail interact with its carbohydrate recognition domain in a phosphorylation-dependent manner. Biochemical and Biophysical Research Communications, 443(1), 126-131. https://doi.org/10.1016/j.bbrc.2013.11.063
    • Nicolaes, G. A. F., Kulharia, M., Voorberg, J., Kaijen, P. H., Wroblewska, A., Wielders, S., Schrijver, R., Sperandio, O., & Villoutreix, B. O. (2014). Rational design of small molecules targeting the C2 domain of coagulation factor VIII. Blood, 123(1), 113-120. https://doi.org/10.1182/blood-2013-05-503227
    • Cornelis, T., van der Sande, F. M., Eloot, S., Cardinaels, E., Bekers, O., Damoiseaux, J., Leunissen, K. M., & Kooman, J. P. (2014). Acute Hemodynamic Response and Uremic Toxin Removal in Conventional and Extended Hemodialysis and Hemodiafiltration: A Randomized Crossover Study.American Journal of Kidney Diseases, 64(2), 247-265. https://doi.org/10.1053/j.ajkd.2014.02.016
    • Erkens, P. M. G., Lucassen, W. A. M., Geersing, G. J., van Weert, H. C. P. M., Kuijs-Augustijn, M., van Heugten, M., Rietjens, L., ten Cate, H., Prins, M. H., Büller, H. R., Hoes, A. W., Moons, K. G. M., Oudega, R., & Stoffers, H. E. J. H. (2014). Alternative diagnoses in patients in whom the GP considered the diagnosis of pulmonary embolism. Family Practice. https://doi.org/10.1093/fampra/cmu055