• 2021
    • Perrella, G., Huang, J., Provenzale, I., Swieringa, F., Heubel-Moenen, F. C. J., Farndale, R. W., Roest, M., van der Meijden, P. E. J., Thomas, M., Ariens, R. A. S., Jandrot-Perrus, M., Watson, S. P., & Heemskerk, J. W. M. (2021). Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation. Arteriosclerosis Thrombosis and Vascular Biology, 41(2), E97-E111. https://doi.org/10.1161/ATVBAHA.120.314641
    • Squiccimarro, E., Jiritano, F., Serraino, G. F., ten Cate, H., Paparella, D., & Lorusso, R. (2021). Quantitative and Qualitative Platelet Derangements in Cardiac Surgery and Extracorporeal Life Support. Journal of Clinical Medicine, 10(4), Article 615. https://doi.org/10.3390/jcm10040615
    • van Paridon, P. C. S., Panova-Noeva, M., van Oerle, R., Schulz, A., Prochaska, J. H., Arnold, N., Schmidtmann, I., Beutel, M., Pfeiffer, N., Muenzel, T., Lackner, K. J., Hackeng, T. M., ten Cate, H., Wild, P. S., & Spronk, H. M. H. (2021). Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample. Thrombosis and Haemostasis, 121(02), 174-181. https://doi.org/10.1055/s-0040-1715897
    • Limperger, V., Kenet, G., Kiesau, B., Koether, M., Schmeiser, M., Langer, F., Juhl, D., Shneyder, M., Franke, A., Klostermeier, U. K., Mesters, R., Ruehle, F., Stoll, M., Steppat, D., Kowalski, D., Rocke, A., Kuta, P., Bajorat, T., Torge, A., ... Nowak-Goettl, U. (2021). Role of prothrombin 19911 A > G polymorphism, blood group and male gender in patients with venous thromboembolism: Results of a German cohort study. Journal of Thrombosis and Thrombolysis, 51(2), 494-501. https://doi.org/10.1007/s11239-020-02169-6
    • Eggebrecht, L., Ludolph, P., Gobel, S., Panova-Noeva, M., Arnold, N., Nagler, M., Bickel, C., Lauterbach, M., Hardt, R., Ten Cate, H., Lackner, K. J., Espinola-Klein, C., Munzel, T., Prochaska, J. H., & Wild, P. S. (2021). Cost saving analysis of specialized, eHealth-based management of patients receiving oral anticoagulation therapy: Results from the thrombEVAL study. Scientific Reports, 11(1), Article 2577. https://doi.org/10.1038/s41598-021-82076-9
    • Calisto, B., Ripoll-Rozada, J., Dowman, L. J., Franck, C., Agten, S., Parker, B. L., Carvalho Veloso, R., Vale, N., Gomes, P., de Sanctis, D., Payne, R. J., & Pereira, P. J. B. (2021). Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates. Cell Chemical Biology, 28(1), 26-33.e8. https://doi.org/10.1016/j.chembiol.2020.10.002
    • van Doorn, W. P. T. M., Stassen, P. M., Borggreve, H. F., Schalkwijk, M. J., Stoffers, J., Bekers, O., & Meex, S. J. R. (2021). A comparison of machine learning models versus clinical evaluation for mortality prediction in patients with sepsis. PLOS ONE, 16(1), Article 0245157. https://doi.org/10.1371/journal.pone.0245157
    • Schumski, A., Ortega-Gómez, A., Wichapong, K., Winter, C., Lemnitzer, P., Viola, J. R., Pinilla-Vera, M., Folco, E., Solis-Mezarino, V., Völker-Albert, M., Maas, S. L., Pan, C., Perez Olivares, L., Winter, J., Hackeng, T., Karlsson, M. C. I., Zeller, T., Imhof, A., Baron, R. M., ... Soehnlein, O. (2021). Endotoxinemia Accelerates Atherosclerosis Through Electrostatic Charge-Mediated Monocyte Adhesion. Circulation, 143(3), 254-266. https://doi.org/10.1161/circulationaha.120.046677
    • Driessen, R. G. H., Heijnen, N. F. L., Hulsewe, R. P. M. G., Holtkamp, J. W. M., Winkens, B., van de Poll, M. C. G., van der Horst, I. C. C., Bergmans, D. C. J. J., & Schnabel, R. M. (2021). Early ICU-mortality in sepsis - causes, influencing factors and variability in clinical judgement: a retrospective cohort study. Infectious Diseases, 53(1), 61-68. https://doi.org/10.1080/23744235.2020.1821912
    • Wu, J. Y., Heemskerk, J. W. M., & Baaten, C. C. F. M. J. (2021). Platelet Membrane Receptor Proteolysis: Implications for Platelet Function. Frontiers in Cardiovascular Medicine, 7, Article 608391. https://doi.org/10.3389/fcvm.2020.608391
    • Dickhout, A., Tullemans, B. M. E., Heemskerk, J. W. M., Thijssen, V. L. J. L., Kuijpers, M. J. E., & Koenen, R. R. (2021). Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro. PLOS ONE, 16(1), Article e0244736. https://doi.org/10.1371/journal.pone.0244736
    • Lagou, V., Mägi, R., Hottenga, J. J., Grallert, H., Perry, J. R. B., Bouatia-Naji, N., Marullo, L., Rybin, D., Jansen, R., Min, J. L., Dimas, A. S., Ulrich, A., Zudina, L., Gådin, J. R., Jiang, L., Faggian, A., Bonnefond, A., Fadista, J., Stathopoulou, M. G., ... Morris, A. P. (2021). Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nature Communications, 12(1), Article 24. https://doi.org/10.1038/s41467-020-19366-9
    • van Moerbeke, A., Magdelijns, F., Cleutjens, F., Boonen, A., & van Onna, M. (2021). Development and Evaluation of a Clinic for Elderly Patients with Rheumatoid Arthritis and Multimorbidity: A Pilot Study. ACR open rheumatology, 3(1), 34-40. https://doi.org/10.1002/acr2.11213
    • Kakkos, S. K., Gohel, M., Baekgaard, N., Bauersachs, R., Bellmunt-Montoya, S., Black, S. A., ten Cate-Hoek, A. J., Elalamy, I., Enzmann, F. K., Geroulakos, G., Gottsater, A., Hunt, B. J., Mansilha, A., Nicolaides, A. N., Sandset, P. M., Stansby, G., de Borst, G. J., Goncalves, F. B., Chakfe, N., ... ESVS Guidelines Committee (2021). Editor's Choice – European Society for Vascular Surgery (ESVS) 2021 Clinical Practice Guidelines on the Management of Venous Thrombosis. European Journal of Vascular and Endovascular Surgery, 61(1), 9-82. https://doi.org/10.1016/j.ejvs.2020.09.023
    • Alexander, Y., Osto, E., Schmidt-Trucksass, A., Shechter, M., Trifunovic, D., Duncker, D. J., Aboyans, V., Back, M., Badimon, L., Cosentino, F., De Carlo, M., Dorobantu, M., Harrison, D. G., Guzik, T. J., Hoefer, I., Morris, P. D., Norata, G. D., Suades, R., Taddei, S., ... Evans, P. C. (2021). Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardioloy working Groups on Artherosclerosis and Vascular Biology, Aorta and Perirpheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis. Cardiovascular Research, 117(1), 29-42. https://doi.org/10.1093/cvr/cvaa085
    • Theunissen, M., Rideaux-Seferina, S., Magdelijns, F. J., Janssen, D. J. A., & van den Beuken-van Everdingen, M. H. J. (2021). Local Oral Pilocarpine Drops for Relieving Xerostomia (Dry Mouth) in the Elderly: A Pilot Study. Journal of the American Medical Directors Association, 22(1), 185-186. https://doi.org/10.1016/j.jamda.2020.06.036
    • Lip, G. Y. H., Rigby, A., & Weber, C. (2021). Looking Back on 2020, Looking Forward to 2021. Thrombosis and Haemostasis, 121(01), 1-3. https://doi.org/10.1055/s-0040-1722198
    • Omarova, F., Rosing, J., Bertina, R. M., & Castoldi, E. (2021). Negatively charged phospholipids stimulate factor XI activation by thrombin. Thrombosis Update, 2, Article 100022. https://doi.org/10.1016/j.tru.2020.100022
    • Brinkman, H. J. M., Ahnstrom, J., Castoldi, E., Dahlback, B., & Marlar, R. A. (2021). Pleiotropic anticoagulant functions of protein S, consequences for the clinical laboratory. Communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis, 19(1), 281-286. https://doi.org/10.1111/jth.15108
    • Kimenai, D. M., Appelman, Y., den Ruijter, H. M., Shah, A. S. V., Mills, N. L., & Meex, S. J. R. (2021). Ten Years of High-Sensitivity Cardiac Troponin Testing: Impact on the Diagnosis of Myocardial Infarction. Clinical Chemistry, 67(1), 324-326. https://doi.org/10.1093/clinchem/hvaa272
    • Weber, C., Rigby, A., & Lip, G. Y. H. (2021). Thrombosis and Haemostasis 2020 Editors' Choice Papers. Thrombosis and Haemostasis, 121(01), 109-114. https://doi.org/10.1055/s-0040-1722171
    • van den Kerkhof, D. L., Nagy, M., Wichapong, K., Brouns, S. L. N., Heemskerk, J. W. M., Hackeng, T. M., & Dijkgraaf, I. (2021). Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integrin inhibitor from ticks. Research and practice in thrombosis and haemostasis, 5(1), 231-242. https://doi.org/10.1002/rth2.12466
    • Wichapong, K., Silvestre-Roig, C., Braster, Q., Schumski, A., Soehnlein, O., & Nicolaes, G. A. F. (2021). Structure-based peptide design targeting intrinsically disordered proteins: Novel histone H4 and H2A peptidic inhibitors. Computational and Structural Biotechnology Journal, 19, 934-948. https://doi.org/10.1016/j.csbj.2021.01.026
    • Cornelissen, L. L., Kreuger, A. L., Caram-Deelder, C., Middelburg, R. A., Kerkhoffs, J. L. H., von dem Borne, P. A., Beckers, E. A. M., de Vooght, K. M. K., Kuball, J., Zwaginga, J. J., & van der Bom, J. G. (2021). Thrombocytopenia and the effect of platelet transfusions on the occurrence of intracranial hemorrhage in patients with acute leukemia - a nested case-control study. Annals of Hematology, 100(1), 261-271. https://doi.org/10.1007/s00277-020-04298-7
    • Schep, S. J., van Dijk, W. E. M., Beckers, E. A. M., Meijer, K., Coppens, M., Eikenboom, J., Leebeek, F. W. G., van Vulpen, L. F. D., Fischer, K. F., Schutgens, R. E. G., & Dutch Society of Haemophilia Treaters (2021). Treatment of acquired hemophilia A, a balancing act: results from a 27-year Dutch cohort study. American Journal of Hematology, 96(1), 51-59. https://doi.org/10.1002/ajh.26009
    • Tullemans, B., Karel, M., Léopold, V., ten Brink, M. S., Baaten, C., Maas, S. L., de Vos, A. F., Eble, J. A., Nijziel, M. R., van der Vorst, E., Cosemans, J., Heemskerk, J., Claushuis, T. A. M., & Kuijpers, M. (2021). Comparison of inhibitory effects of irreversible and reversible Btk inhibitors on platelet function. eJHaem, 2(4), 685–699. https://doi.org/10.1002/jha2.269
  • 2020
    • Kontos, C., El Bounkari, O., Krammer, C., Sinitski, D., Hille, K., Zan, C., Yan, G., Wang, S., Gao, Y., Brandhofer, M., Megens, R. T. A., Hoffmann, A., Pauli, J., Asare, Y., Gerra, S., Bourilhon, P., Leng, L., Eckstein, H.-H., Kempf, W. E., ... Bernhagen, J. (2020). Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting. Nature Communications, 11(1), Article 5981. https://doi.org/10.1038/s41467-020-19764-z
    • De Luca, G., Cercek, M., Jensen, L. O., Vavlukis, M., Calmac, L., Johnson, T., Roura i Ferrer, G., Ganyukov, V., Wojakowski, W., von Birgelen, C., Versaci, F., Ten Berg, J., Laine, M., Dirksen, M., Casella, G., Kala, P., Diez Gil, J. L., Becerra, V., De Simone, C., ... Verdoia, M. (2020). Impact of COVID-19 pandemic and diabetes on mechanical reperfusion in patients with STEMI: insights from the ISACS STEMI COVID 19 Registry. Cardiovascular Diabetology, 19(1), Article 215. https://doi.org/10.1186/s12933-020-01196-0
    • van Geffen, J. P., Swieringa, F., van Kuijk, K., Tullemans, B. M. E., Solari, F. A., Peng, B., Clemetson, K. J., Farndale, R. W., Dubois, L. J., Sickmann, A., Zahedi, R. P., Ahrends, R., Biessen, E. A. L., Sluimer, J. C., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2020). Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome. Scientific Reports, 10(1), Article 21407. https://doi.org/10.1038/s41598-020-78522-9
    • Hamid, S. M., Citir, M., Terzi, E. M., Cimen, I., Yildirim, Z., Dogan, A. E., Kocaturk, B., Onat, U. I., Arditi, M., Weber, C., Traynor-Kaplan, A., Schultz, C., & Erbay, E. (2020). Inositol-requiring enzyme-1 regulates phosphoinositide signaling lipids and macrophage growth. Embo Reports, 21(12), Article 51462. https://doi.org/10.15252/embr.202051462
    • Santovito, D., Egea, V., Bidzhekov, K., Natarelli, L., Mourao, A., Blanchet, X., Wichapong, K., Aslani, M., Brunssen, C., Horckmans, M., Hristov, M., Geerlof, A., Lutgens, E., Daemen, M. J. A. P., Hackeng, T., Ries, C., Chavakis, T., Morawietz, H., Naumann, R., ... Weber, C. (2020). Autophagy unleashes noncanonical microRNA functions. Autophagy, 16(12), 2294-2296. https://doi.org/10.1080/15548627.2020.1830523
    • Evans, P. C., Rainger, G. E., Mason, J. C., Guzik, T. J., Osto, E., Stamataki, Z., Neil, D., Hoefer, I. E., Fragiadaki, M., Waltenberger, J., Weber, C., Bochaton-Piallat, M.-L., & Bäck, M. (2020). Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science. Cardiovascular Research, 116(14), 2177-2184. https://doi.org/10.1093/cvr/cvaa230
    • Denessen, E. J. S., Jeurissen, M. L. J., Pereboom, R. M. T. A., Verhezen, P. W. M., & Henskens, Y. M. C. (2020). Determining the maximal storage time of centrifuged citrated samples for performing add-on routine coagulation tests. Thrombosis Research, 196, 54-62. https://doi.org/10.1016/j.thromres.2020.08.003
    • Gencer, S., Lacy, M., Atzler, D., van der Vorst, E. P. C., Doering, Y., & Weber, C. (2020). Immunoinflammatory, Thrombohaemostatic, and Cardiovascular Mechanisms in COVID-19. Thrombosis and Haemostasis, 120(12), 1629-1641. https://doi.org/10.1055/s-0040-1718735
    • Seelig, J., Hemels, M. E. W., Xhaet, O., Bongaerts, M. C. M., de Wolf, A., Groenemeijer, B. E., Heyse, A., Hoogslag, P., Voet, J., Herrman, J.-P. R., Vervoort, G., Hermans, W., Wollaert, B., Boersma, L. V. A., Hermans, K., Lucassen, A., Verstraete, S., Adriaansen, H. J., Mairesse, G. H., ... GARFIELD-AF Investigators (2020). Impact of different anticoagulation management strategies on outcomes in atrial fibrillation: Dutch and Belgian results from the GARFIELD-AF registry. Journal of Thrombosis and Haemostasis, 18(12), 3280-3288. https://doi.org/10.1111/jth.15081
    • Bavalia, R., Abdoellakhan, R., Beenen, L. F., Brekelmans, M. P. A., Olie, R. H., ten Cate, H., Huisman, M., Kruip, M., Middeldorp, S., Meijer, K., Hutten, B. A., & Coppens, M. (2020). Outcome of intracranial bleeding managed with prothrombin complex concentrate in patients on direct factor Xa inhibitors or vitamin K antagonists. Thrombosis Research, 196, 404-409. https://doi.org/10.1016/j.thromres.2020.09.028
    • Abdi, A., Kloosterman, F. R., Eckhardt, C. L., Male, C., Castaman, G., Fischer, K., Beckers, E. A. M., Kruip, M. J. H. A., Peerlinck, K., Mancuso, M. E., Santoro, C., Hay, C. R., Platokouki, H., van Der Bom, J. G., Gouw, S. C., Fijnvandraat, K., Hart, D. P., & INSIGHT Study Group (2020). The factor VIII treatment history of non-severe hemophilia A. Journal of Thrombosis and Haemostasis, 18(12), 3203-3210. https://doi.org/10.1111/jth.15076
    • Bruggemann, R. A. G., Spaetgens, B., Gietema, H. A., Brouns, S. H. A., Stassen, P. M., Magdelijns, F. J., Rennenberg, R. J., Henry, R. M. A., Mulder, M. M. G., van Bussel, B. C. T., Schnabel, R. M., van der Horst, I. C. C., Wildberger, J. E., Stehouwer, C. D. A., & ten Cate, H. (2020). The prevalence of pulmonary embolism in patients with COVID-19 and respiratory decline: A three-setting comparison. Thrombosis Research, 196, 486-490. https://doi.org/10.1016/j.thromres.2020.10.012
    • Schiffer, V. M. M. M., Janssen, E. B. N. J., van Bussel, B. C. T., Jorissen, L. L. M., Tas, J., Sels, J.-W. E. M., Bergmans, D. C. J. J., Dinh, T. H. T., van Kuijk, S. M. J., Hana, A., Mehagnoul-Schipper, J., Scheeren, C. I. E., Mesotten, D., Stessel, B., Marx, G., Hof, A. W. J. V. T., Spaanderman, M. E. A., van Mook, W. N. K. A., van der Horst, I. C. C., & Ghossein-Doha, C. (2020). The "sex gap" in COVID-19 trials: a scoping review. EClinicalMedicine, 29-30, Article 100652. https://doi.org/10.1016/j.eclinm.2020.100652
    • Winters, J., von Braunmuhl, M. E., Zeemering, S., Gilbers, M., Ten Brink, T., Scaf, B., Guasch, E., Mont, L., Batlle, M., Sinner, M., Hatem, S., Mansour, M. K., Fabritz, L., Sommerfeld, L. C., Kirchhof, P., Isaacs, A., Stoll, M., Schotten, U., & Verheule, S. (2020). JavaCyte, a novel open-source tool for automated quantification of key hallmarks of cardiac structural remodeling. Scientific Reports, 10(1), Article 20074. https://doi.org/10.1038/s41598-020-76932-3
    • De Luca, G., Verdoia, M., Cercek, M., Jensen, L. O., Vavlukis, M., Calmac, L., Johnson, T., Ferrer, G. R., Ganyukov, V., Wojakowski, W., Kinnaird, T., van Birgelen, C., Cottin, Y., IJsselmuiden, A., Tuccillo, B., Versaci, F., Royaards, K.-J., Ten Berg, J., Laine, M., ... Dudek, D. (2020). Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI. Journal of the American College of Cardiology, 76(20), 2321-2330. https://doi.org/10.1016/j.jacc.2020.09.546
    • Willemsen, L. M., Janssen, P. W. A., Peper, J., Soliman-Hamad, M. A., van Straten, A. H. M., Klein, P., Hackeng, C. M., Sonker, U., Bekker, M. W. A., von Birgelen, C., Brouwer, M. A., van der Harst, P., Vlot, E. A., Deneer, V. H. M., Yin, D. R. P. P. C. P., Gimbel, M. E., Beukema, K. F., Daeter, E. J., Kelder, J. C., ... ten berg, J. M. (2020). Effect of Adding Ticagrelor to Standard Aspirin on Saphenous Vein Graft Patency in Patients Undergoing Coronary Artery Bypass Grafting (POPular CABG): A Randomized, Double-Blind, Placebo-Controlled Trial. Circulation, 142(19), 1799-1807. https://doi.org/10.1161/CIRCULATIONAHA.120.050749
    • Mastenbroek, T. G., Karel, M. F. A., Nagy, M., Chayoua, W., Korsten, E. I. J., Coenen, D. M., Debets, J., Konings, J., Brouns, A. E., Leenders, P. J. A., van Essen, H., van Oerle, R., Heitmeier, S., Spronk, H. M., Kuijpers, M. J. E., & Cosemans, J. M. E. M. (2020). Vascular protective effect of aspirin and rivaroxaban upon endothelial denudation of the mouse carotid artery. Scientific Reports, 10(1), Article 19360. https://doi.org/10.1038/s41598-020-76377-8
    • Busch, M. H., Timmermans, S. A. M. E. G., Nagy, M., Visser, M., Huckriede, J., Aendekerk, J. P., de Vries, F., Potjewijd, J., Jallah, B., Ysermans, R., Oude Lashof, A. M. L., Breedveld, P. H., van de Poll, M. C. G., van de Horst, I. C. C., van Bussel, B. C. T., Theunissen, R. O. M. F. I. H., Spronk, H. M. H., Damoiseaux, J. G. M. C., ten Cate, H., ... van Paassen, P. (2020). Neutrophils and Contact Activation of Coagulation as Potential Drivers of COVID-19. Circulation, 142(18), 1787-1790. https://doi.org/10.1161/CIRCULATIONAHA.120.050656
    • Valke, L. L. F. G., Beckers, E. A. M., Blijlevens, N. M. A., van Heerde, W. L., & Schols, S. E. M. (2020). Effect of emicizumab on thrombin generation: A case report of breakthrough bleeding during emicizumab treatment. Haemophilia, 26(6), E327-E330. https://doi.org/10.1111/hae.14085
    • Kiouptsi, K., Pontarollo, G., Todorov, H., Braun, J., Jaeckel, S., Koeck, T., Bayer, F., Karwot, C., Karpi, A., Gerber, S., Jansen, Y., Wild, P., Ruf, W., Daiber, A., van der Vorst, E., Weber, C., Doering, Y., & Reinhardt, C. (2020). Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice. Gut Microbes, 11(6), 1809-1823. https://doi.org/10.1080/19490976.2020.1767463