• 2019
    • van der Vorst, E. P. C., Mandl, M., Mueller, M., Neideck, C., Jansen, Y., Hristov, M., Gencer, S., Peters, L. J. F., Meiler, S., Feld, M., Geiselhoeringer, A.-L., de Jong, R. J., Ohnmacht, C., Noels, H., Soehnlein, O., Drechsler, M., Weber, C., & Doering, Y. (2019). Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions-Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 39(4), 685-693. https://doi.org/10.1161/ATVBAHA.119.312386
    • Steffens, S., & Weber, C. (2019). Immunotherapy for Atherosclerosis-Novel Concepts. Thrombosis and Haemostasis, 119(4), 515-516. https://doi.org/10.1055/s-0039-1683451
    • Posthuma, J. J., Posma, J. J. N., Schep, G., Bender, M. M. H., van Oerle, R., van der Wal, A. C., Ten Cate, H., & Spronk, H. M. H. (2019). Protease-activated receptors are potential regulators in the development of arterial endofibrosis in high-performance athletes. Journal of Vascular Surgery, 69(4), 1243-1250. https://doi.org/10.1016/j.jvs.2018.05.220
    • Brouwers, M. C. G. J., Simons, N., Stehouwer, C. D. A., Koek, G. H., Schaper, N. C., & Isaacs, A. (2019). Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease. Hepatology communications, 3(4), 587-596. https://doi.org/10.1002/hep4.1319
    • Schulz, A., Mueller, N. V., van de Lest, N. A., Eisenreich, A., Schmidbauer, M., Barysenka, A., Purfuerst, B., Sporbert, A., Lorenzen, T., Meyer, A. M., Herlan, L., Witten, A., Ruehle, F., Zhou, W., de Heer, E., Scharpfenecker, M., Panakova, D., Stoll, M., & Kreutz, R. (2019). Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage. Elife, 8, Article 42068. https://doi.org/10.7554/eLife.42068
    • Mueller, M. M., Van Remoortel, H., Meybohm, P., Aranko, K., Aubron, C., Burger, R., Carson, J. L., Cichutek, K., De Buck, E., Devine, D., Fergusson, D., Folléa, G., French, C., Frey, K. P., Gammon, R., Levy, J. H., Murphy, M. F., Ozier, Y., Pavenski, K., ... ICC PBM Frankfurt 2018 Group (2019). Patient Blood Management: Recommendations from the 2018 Frankfurt Consensus Conference. JAMA-Journal of the American Medical Association, 321(10), 983-997. https://doi.org/10.1001/jama.2019.0554
    • Krekels, J. P. M., Verhezen, P. W. M., & Henskens, Y. M. C. (2019). Platelet Aggregation in Healthy Participants is Not Affected by Smoking, Drinking Coffee, Consuming a High-Fat Meal, or Performing Physical Exercise. Clinical and Applied Thrombosis-Hemostasis, 25, 1-9. Article 1076029618782445. https://doi.org/10.1177/1076029618782445
    • Posthuma, J. J., Posma, J. J. N., van Oerle, R., Leenders, P., van Gorp, R. H., Jaminon, A. M. G., Mackman, N., Heitmeier, S., Schurgers, L. J., ten Cate, H., & Spronk, H. M. H. (2019). Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice. Scientific Reports, 9(1), Article 3909. https://doi.org/10.1038/s41598-019-40602-w
    • Ibrahim-Kosta, M., Suchon, P., Couturaud, F., Smadja, D., Olaso, R., Germain, M., Saut, N., Goumidi, L., Derbois, C., Thibord, F., Debette, S., Amouyel, P., Deleuze, J. F., van Doorn, P., Castoldi, E., Patin, E., Alessi, M. C., Tregouet, D. A., & Morange, P. E. (2019). Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation. Scientific Reports, 9(1), Article 3750. https://doi.org/10.1038/s41598-019-40172-x
    • Döring, Y., van der Vorst, E. P. C., Duchene, J., Jansen, Y., Gencer, S., Bidzhekov, K., Atzler, D., Santovito, D., Rader, D. J., Saleheen, D., & Weber, C. (2019). CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease. Circulation, 139(10), 1338-1340. https://doi.org/10.1161/CIRCULATIONAHA.118.037953
    • Cremer, S., Michalik, K. M., Fischer, A., Pfisterer, L., Jae, N., Winter, C., Boon, R. A., Muhly-Reinholz, M., John, D., Uchida, S., Weber, C., Poller, W., Guenther, S., Braun, T., Li, D. Y., Maegdefessel, L., Matic, L. P., Hedin, U., Soehnlein, O., ... Dimmeler, S. (2019). Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation. Circulation, 139(10), 1320-1334. https://doi.org/10.1161/circulationaha.117.029015
    • Yin, C., Ackermann, S., Ma, Z., Mohanta, S. K., Zhang, C., Li, Y., Nietzsche, S., Westermann, M., Peng, L., Hu, D., Bontha, S. V., Srikakulapu, P., Beer, M., Megens, R. T. A., Steffens, S., Hildner, M., Halder, L. D., Eckstein, H.-H., Pelisek, J., ... Habenicht, A. J. R. (2019). ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nature Medicine, 25(3), 496-506. https://doi.org/10.1038/s41591-018-0336-8
    • Wijnen, P., Drent, M., Bekers, O., Verschakelen, J., & Bast, A. (2019). VKORC1 and CYP2C9 Polymorphisms: A Case Report in a Dutch Family with Pulmonary Fibrosis. International journal of molecular sciences, 20(5), Article 1160. https://doi.org/10.3390/ijms20051160
    • Schloss, M. J., Horckmans, M., Guillamat-Prats, R., Hering, D., Lauer, E., Lenglet, S., Weber, C., Thomas, A., & Steffens, S. (2019). 2-Arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction. Cardiovascular Research, 115(3), 602-613. https://doi.org/10.1093/cvr/cvy242
    • Vroemen, W. H. M., Mezger, S. T. P., Masotti, S., Clerico, A., Bekers, O., de Boer, D., & Mingels, A. (2019). Cardiac Troponin T: Only Small Molecules in Recreational Runners After Marathon Completion. Journal of Applied Laboratory Medicine, 3(5), 909-911. https://doi.org/10.1373/jalm.2018.027144
    • Gandhi, S., Ruehle, F., & Stoll, M. (2019). Evolutionary Patterns of Non-Coding RNA in Cardiovascular Biology. Non-coding RNA, 5(1), Article 15. https://doi.org/10.3390/ncrna5010015
    • Denzinger, V., Busygina, K., Jamasbi, J., Pekrul, I., Spannagl, M., Weber, C., Lorenz, R., & Siess, W. (2019). Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib. Thrombosis and Haemostasis, 119(3), 397-406. https://doi.org/10.1055/s-0039-1677744
    • van der Meijden, P. E. J., & Heemskerk, J. W. M. (2019). Platelet biology and functions: new concepts and clinical perspectives. Nature Reviews Cardiology, 16(3), 166-179. https://doi.org/10.1038/s41569-018-0110-0
    • Donkel, S. J., Benaddi, B., Dippel, D. W. J., ten Cate, H., & de Maat, M. P. M. (2019). Prognostic Hemostasis Biomarkers in Acute Ischemic Stroke: A Systematic Review. Arteriosclerosis Thrombosis and Vascular Biology, 39(3), 360-372. https://doi.org/10.1161/ATVBAHA.118.312102
    • Yin, C., Ackermann, S., Ma, Z., Mohanta, S. K., Zhang, C., Li, Y., Nietzsche, S., Westermann, M., Peng, L., Hu, D., Bontha, S. V., Srikakulapu, P., Beer, M., Megens, R. T. A., Steffens, S., Hildner, M., Halder, L. D., Eckstein, H.-H., Pelisek, J., ... Habenicht, A. J. R. (2019). Publisher Correction: ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nature Medicine, 25(3), 529-529. https://doi.org/10.1038/s41591-019-0378-6
    • Shvetsova, E., Sofronova, A., Monajemi, R., Gagalova, K., Draisma, H. H. M., White, S. J., Santen, G. W. E., Lopes, S. M. C. D. S., Heijmans, B. T., van Meurs, J., Jansen, R., Franke, L., Kielbasa, S. M., den Dunnen, J. T., 't Hoen, P. A. C., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., ... GoNL consortium (2019). Skewed X-inactivation is common in the general female population. European Journal of Human Genetics, 27(3), 455-465. https://doi.org/10.1038/s41431-018-0291-3
    • Adrover, J. M., del Fresno, C., Crainiciuc, G., Isabel Cuartero, M., Casanova-Acebes, M., Weiss, L. A., Huerga-Encabo, H., Silvestre-Roig, C., Rossaint, J., Cossio, I., Lechuga-Vieco, A. V., Garcia-Prieto, J., Gomez-Parrizas, M., Quintana, J. A., Ballesteros, I., Martin-Salamanca, S., Aroca-Crevillen, A., Chong, S. Z., Evrard, M., ... Hidalgo, A. (2019). A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. Immunity, 50(2), 390-402.e10. https://doi.org/10.1016/j.immuni.2019.01.002
    • Denisov, S. S., Ippel, J. H., Mans, B. J., Dijkgraaf, I., & Hackeng, T. M. (2019). SecScan: a general approach for mapping disulfide bonds in synthetic and recombinant peptides and proteins. Chemical Communications, 55(10), 1374-1377. https://doi.org/10.1039/c8cc08777f
    • Koenen, R. R. (2019). No hearty reception: infusion of CXCL4 impedes tissue repair by macrophages after myocardial infarction. Cardiovascular Research, 115(2), 264-265. https://doi.org/10.1093/cvr/cvy241
    • Vries, M. J. A., Macrae, F., Nelemans, P. J., Kuiper, G. J. A. J. M., Wetzels, R. J. H., Bowman, P., Verhezen, P. W. M., ten Cate, H., Ariens, R. A. S., & Henskens, Y. M. C. (2019). Assessment and determinants of whole blood and plasma fibrinolysis in patients with mild bleeding symptoms. Thrombosis Research, 174, 88-94. https://doi.org/10.1016/j.thromres.2018.12.004
    • Pfeiler, S., Thakur, M., Gruenauer, P., Megens, R. T. A., Joshi, U., Coletti, R., Samara, V., Mueller-Stoy, G., Ishikawa-Ankerhold, H., Stark, K., Klingl, A., Froehlich, T., Arnold, G. J., Woermann, S., Bruns, C. J., Alguel, H., Weber, C., Massberg, S., & Engelmann, B. (2019). CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis. Faseb Journal, 33(2), 1860-1872. https://doi.org/10.1096/fj.201800985R
    • Prats, R. G., Rami, M., Ring, L., Rinne, P., Lauer, E., Lenglet, S., Thomas, A., Pagano, S., Vuilleumier, N., Cravatt, B. F., Weber, C., Faussner, A., & Steffens, S. (2019). Deficiency of Monoacylglycerol Lipase Enhances IgM Plasma Levels and Limits Atherogenesis in a CB2-Dependent Manner. Thrombosis and Haemostasis, 119(2), 348-351. https://doi.org/10.1055/s-0038-1676769
    • Driessen, J. H. M., de Vries, F., van Onzenoort, H. A. W., Schram, M. T., van der Kallen, C., Reesink, K. D., Sep, S., Stehouwer, C. D. A., Schaper, N., Kroon, A. A., Schalkwijk, C., van den Bergh, J. P. W., & Henry, R. M. A. (2019). Metformin use in type 2 diabetic patients is not associated with lower arterial stiffness: the Maastricht Study. Journal of Hypertension, 37(2), 365-371. https://doi.org/10.1097/HJH.0000000000001892
    • van der Vorst, E. P. C., & Weber, C. (2019). Novel Features of Monocytes and Macrophages in Cardiovascular Biology and Disease. Arteriosclerosis Thrombosis and Vascular Biology, 39(2), E30-E37. https://doi.org/10.1161/ATVBAHA.118.312002
    • Sabrkhany, S., Kuijpers, M. J. E., Griffioen, A. W., & Egbrink, M. G. A. O. (2019). Platelets: the holy grail in cancer blood biomarker research?Angiogenesis, 22(1), 1-2. https://doi.org/10.1007/s10456-018-9651-4
    • Kuiper, G. J. A. J. M., van Egmond, L. T., Henskens, Y. M. C., Roekaerts, P. M., Maessen, J. G., ten Cate, H., Buhre, W. F., & Lance, M. D. (2019). Shifts of Transfusion Demand in Cardiac Surgery After Implementation of Rotational Thromboelastometry-Guided Transfusion Protocols: Analysis of the HEROES-CS (HEmostasis Registry of patiEntS in Cardiac Surgery) Observational, Prospective Open Cohort Database. Journal of Cardiothoracic and Vascular Anesthesia, 33(2), 307-317. https://doi.org/10.1053/j.jvca.2018.08.203
    • Chauhan, G., Adams, H. H. H., Satizabal, C. L., Bis, J. C., Teumer, A., Sargurupremraj, M., Hofer, E., Trompet, S., Hilal, S., Smith, A. V., Jian, X., Malik, R., Traylor, M., Pulit, S. L., Amouyel, P., Mazoyer, B., Zhu, Y.-C., Kaffashian, S., Schilling, S., ... Isaacs, A. (2019). Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology, 92(5), E486-E503. https://doi.org/10.1212/WNL.0000000000006851
    • Seijkens, T. T. P., Poels, K., Meiler, S., van Tiel, C. M., Kusters, P. J. H., Reiche, M., Atzler, D., Winkels, H., Tjwa, M., Poelman, H., Slutter, B., Kuiper, J., Gijbels, M., Kuivenhoven, J. A., Matic, L. P., Paulsson-Berne, G., Hedin, U., Hansson, G. K., Nicolaes, G. A. F., ... Lutgens, E. (2019). Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death. European Heart Journal, 40(4), 372-382. https://doi.org/10.1093/eurheartj/ehy714
    • Grottke, O., van Ryn, J., Zentai, C., Gan, G., Honickel, M., Rossaint, R., Ten Cate, H., & Spronk, H. M. H. (2019). Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution. PLOS ONE, 14(1), e0209350. Article 0209350. https://doi.org/10.1371/journal.pone.0209350
    • Moenen, F. C. J., Vries, M. J. A., Nelemans, P. J., van Rooy, K. J. M., Vranken, J. R. R. A., Verhezen, P. W. M., Wetzels, R. J. H., ten Cate, H., Schouten, H. C., Beckers, E. A. M., & Henskens, Y. M. C. (2019). Screening for platelet function disorders with Multiplate and platelet function analyzer. Platelets, 30(1), 81-87. https://doi.org/10.1080/09537104.2017.1371290
    • Benedikter, B. J., Bouwman, F. G., Heinzmann, A. C. A., Vajen, T., Mariman, E. C., Wouters, E. F. M., Savelkoul, P. H. M., Koenen, R. R., Rohde, G. G. U., van Oerle, R., Spronk, H. M., & Stassen, F. R. M. (2019). Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles. Journal of Extracellular Vesicles, 8(1), Article 1585163. https://doi.org/10.1080/20013078.2019.1585163
    • Schuett, J., Kreutz, J., Grote, K., Vlacil, A. K., Schuett, H., Oberoi, R., Schmid, A., Witten, A., Stoll, M., Schieffer, B., & Rühle, F. (2019). Suppressor of Cytokine Signaling 1 is Involved in Gene Regulation Which Controls the Survival of Ly6C low Monocytes in Mice. Cellular Physiology and Biochemistry, 52(2), 336-353. https://doi.org/10.33594/000000024
    • Nielen, J. T. H., de Vries, F., van der Velde, J. H. P. M., Savelberg, H. H. C. M., Schaper, N. C., Dagnelie, P. C., Henry, R. M. A., Schram, M., Stehouwer, C. D. A., Boonen, A., Koster, A., & van den Bemt, B. J. F. (2019). The Association Between β-Blocker Use and Cardiorespiratory Fitness: The Maastricht Study. Journal of Cardiovascular Pharmacology and Therapeutics, 24(1), 37-45. https://doi.org/10.1177/1074248418778551
    • Peeters, F. E. C. M., Kietselaer, B. L. J. H., Hilderink, J., van der Linden, N., Niens, M., Crijns, H. J. G. M., & Meex, S. J. R. (2019). Biological variation of cardiac markers in patients with aortic valve stenosis. Open Heart, 6(1), Article 001040. https://doi.org/10.1136/openhrt-2019-001040
    • Luijten, J., van Greevenbroek, M. M. J., Schaper, N. C., Meex, S. J. R., van der Steen, C., Meijer, L. J., de Boer, D., de Graaf, J., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2019). Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study. Atherosclerosis, 280, 1-6. https://doi.org/10.1016/j.atherosclerosis.2018.11.013
    • Leader, A., Ten Cate, V., Ten Cate-Hoek, A. J., Spectre, G., Beckers, E. A. M., Raanani, P., Giaccherini, C., Pereg, D., Schouten, H. C., Falanga, A., & Ten Cate, H. (2019). Managing Anti-Platelet Therapy in Thrombocytopaenic Patients with Haematological Malignancy: A Multinational Clinical Vignette-Based Experiment. Thrombosis and Haemostasis, 119(1), 163-174. https://doi.org/10.1055/s-0038-1676520
    • Meani, P., Delnoij, T., Raffa, G. M., Morici, N., Viola, G., Sacco, A., Oliva, F., Heuts, S., Sels, J.-W., Driessen, R., Roekaerts, P., Gilbers, M., Bidar, E., Schreurs, R., Natour, E., Veenstra, L., Kats, S., Maessen, J., & Lorusso, R. (2019). Protracted aortic valve closure during peripheral veno-arterial extracorporeal life support: is intra-aortic balloon pump an effective solution?Perfusion, 34(1), 35-41. https://doi.org/10.1177/0267659118787426
    • Posma, J. J., Grover, S. P., Hisada, Y., Owens, A. P., Antoniak, S., Spronk, H. M., & Mackman, N. (2019). Roles of Coagulation Proteases and PARs (Protease-Activated Receptors) in Mouse Models of Inflammatory Diseases. Arteriosclerosis Thrombosis and Vascular Biology, 39(1), 13-24. https://doi.org/10.1161/ATVBAHA.118.311655
    • Atiq, F., Mauser-Bunschoten, E. P., Eikenboom, J., van Galen, K. P. M., Meijer, K., de Meris, J., Cnossen, M. H., Beckers, E. A. M., Laros-van Gorkom, B. A. P., Nieuwenhuizen, L., van der Bom, J. G., Fijnvandraat, K., Leebeek, F. W. G., & WiN Study Group (2019). Sports participation and physical activity in patients with von Willebrand disease. Haemophilia, 25(1), 101-108. https://doi.org/10.1111/hae.13629
    • Bucerius, J., Dijkgraaf, I., Mottaghy, F. M., & Schurgers, L. J. (2019). Target identification for the diagnosis and intervention of vulnerable atherosclerotic plaques beyond 18F-fluorodeoxyglucose positron emission tomography imaging: promising tracers on the horizon. European Journal of Nuclear Medicine and Molecular Imaging, 46(1), 251-265. https://doi.org/10.1007/s00259-018-4176-z
    • Ratzon, R., Tamir, S., Friehmann, T., Livneh, N., Dudnik, E., Rozental, A., Hamburger-Avnery, O., Pereg, D., Derazne, E., Brenner, B., Raanani, P., ten Cate, H., Spectre, G., & Leader, A. (2019). Thrombosis, anticoagulation and outcomes in malignant superior vena cava syndrome. Journal of Thrombosis and Thrombolysis, 47(1), 121-128. https://doi.org/10.1007/s11239-018-1747-6
    • Davey, N. E., Babu, M. M., Blackledge, M., Bridge, A., Capella-Gutierrez, S., Dosztanyi, Z., Drysdale, R., Edwards, R. J., Elofsson, A., Felli, I. C., Gibson, T. J., Gutmanas, A., Hancock, J. M., Harrow, J., Higgins, D., Jeffries, C. M., Le Mercier, P., Mészáros, B., Necci, M., ... Tosatto, S. C. E. (2019). An intrinsically disordered proteins community for elixir [version 1; peer review: 2 approved]. F1000Research, 8, 1-19. https://doi.org/10.12688/f1000research.20136.1
    • Oshagbemi, O. A., Franssen, F. M. E., van Kraaij, S., Braeken, D. C. W., Wouters, E. F. M., Maitland-van der Zee, A. H., Driessen, J. H. M., & de Vries, F. (2019). Blood Eosinophil Counts, Withdrawal of Inhaled Corticosteroids and Risk of COPD Exacerbations and Mortality in the Clinical Practice Research Datalink (CPRD). COPD, 16(2), 152-159. https://doi.org/10.1080/15412555.2019.1608172
    • Cheung, C. Y., Chan, K. M., Wong, Y. T., Chak, W. L., Bekers, O., & van Hooff, J. P. (2019). Impact of CYP3A5 Genetic Polymorphism on Intrapatient Variability of Tacrolimus Exposure in Chinese Kidney Transplant Recipients. Transplantation Proceedings, 51(6), 1754-1757. https://doi.org/10.1016/j.transproceed.2019.04.019