• 2021
    • Naesens, L., Penicka, M., & Heggermont, W. (2021). Diagnosis and immunosuppressive treatment of inflammatory cardiomyopathy: a case report. Acta Clinica Belgica, 76(5), 415-419. https://doi.org/10.1080/17843286.2020.1747714
    • Raso, A., Dirkx, E., Sampaio-Pinto, V., el Azzouzi, H., Cubero, R. J., Sorensen, D. W., Ottaviani, L., Olieslagers, S., Huibers, M. M., de Weger, R., Siddiqi, S., Moimas, S., Torrini, C., Zentillin, L., Braga, L., Nascimento, D. S., da Costa Martins, P. A., van Berlo, J. H., Zacchigna, S., ... De Windt, L. J. (2021). A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration. Nature Communications, 12(1), [4808]. https://doi.org/10.1038/s41467-021-25211-4
    • Abreu, R. C., Ramos, C., Becher, C., Lino, M., Jesus, C., da Costa Martins, P. A., Martins, P. A. T., Moreno, M. J., Fernandes, H., & Ferreira, L. (2021). Exogenous loading of miRNAs into small extracellular vesicles. Journal of Extracellular Vesicles , 10(10), [12111]. https://doi.org/10.1002/jev2.12111
    • Simonavicius, J., Maeder, M. T., Eurlings, C. G. M. J., Aizpurua, A. B., Celutkiene, J., Barysiene, J., Toggweiler, S., Kaufmann, B. A., & Brunner-La Rocca, H-P. (2021). Intensification of pharmacological decongestion but not the actual daily loop diuretic dose predicts worse chronic heart failure outcome: insights from TIME-CHF. Clinical research in cardiology, 110(8), 1221-1233. https://doi.org/10.1007/s00392-020-01779-7
    • Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2021). Placental Mitochondrial Abnormalities in Preeclampsia. Reproductive Sciences, 28(8), 2186-2199. https://doi.org/10.1007/s43032-021-00464-y
    • Marcks, N., Aimo, A., Januzzi, J. L., Vergaro, G., Clerico, A., Latini, R., Meessen, J., Anand, I. S., Cohn, J. N., Gravning, J., Ueland, T., Bayes-Genis, A., Lupón, J., de Boer, R. A., Yoshihisa, A., Takeishi, Y., Egstrup, M., Gustafsson, I., Gaggin, H. K., ... Brunner-La Rocca, H-P. (2021). Re-appraisal of the obesity paradox in heart failure: a meta-analysis of individual data. Clinical research in cardiology, 110(8), 1280-1291. https://doi.org/10.1007/s00392-021-01822-1
    • Gentile, P., Merlo, M., Peretto, G., Ammirati, E., Sala, S., Della Bella, P., Aquaro, G. D., Imazio, M., Potena, L., Campodonico, J., Foa, A., Raafs, A., Hazebroek, M., Brambatti, M., Cercek, A. C., Nucifora, G., Shrivastava, S., Huang, F., Schmidt, M., ... Sinagra, G. (2021). Post-discharge arrhythmic risk stratification of patients with acute myocarditis and life-threatening ventricular tachyarrhythmias. European journal of heart failure. https://doi.org/10.1002/ejhf.2288
    • Verdonschot, J. A. J., Henkens, M. T. H. M., Wang, P., Schummers, G., Raafs, A. G., Krapels, I. P. C., van Empel, V., Heymans, S. R. B., Brunner-La Rocca, H-P., & Knackstedt, C. (2021). A global longitudinal strain cut-off value to predict adverse outcomes in individuals with a normal ejection fraction. Esc heart failure. https://doi.org/10.1002/ehf2.13465
    • Veugen, M. G. J., Linssen, P. B. C., Henry, R. M. A., Koster, A., Kroon, A. A., Stehouwer, C. D. A., & Brunner-La Rocca, H-P. (2021). Measures of Left Ventricular Diastolic Function and Cardiorespiratory Fitness According to Glucose Metabolism Status: The Maastricht Study. Journal of the American Heart Association, 10(13), [020387]. https://doi.org/10.1161/jaha.120.020387
    • Breuls, N., Giarratana, N., Yedigaryan, L., Garrido, G. M., Carai, P., Heymans, S., Ranga, A., Deroose, C., & Sampaolesi, M. (2021). Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a NOTCH-dependent manner. Cell Death & Disease, 12(7), [677]. https://doi.org/10.1038/s41419-021-03936-w
    • Uijl, A., Veenis, J. F., Brunner-La Rocca, H. P., van Empel, V., Linssen, G. C. M., Asselbergs, F. W., van der Lee, C., Eurlings, L. W. M., Kragten, H., Al-Windy, N. Y. Y., van der Spank, A., Koudstaal, S., Brugts, J. J., & Hoes, A. W. (2021). Clinical profile and contemporary management of patients with heart failure with preserved ejection fraction: results from the CHECK-HF registry. Netherlands Heart Journal, 29(7-8), 370-376. https://doi.org/10.1007/s12471-020-01534-7
    • Ploeg, M. C., Munts, C., Prinzen, F. W., Turner, N. A., van Bilsen, M., & van Nieuwenhoven, F. A. (2021). Piezo1 Mechanosensitive Ion Channel Mediates Stretch-Induced Nppb Expression in Adult Rat Cardiac Fibroblasts. Cells, 10(7), [1745]. https://doi.org/10.3390/cells10071745
    • Franken, G., Douven, P., Debets, J., & Joosten, E. A. J. (2021). Conventional Dorsal Root Ganglion Stimulation in an Experimental Model of Painful Diabetic Peripheral Neuropathy: A Quantitative Immunocytochemical Analysis of Intracellular gamma-Aminobutyric Acid in Dorsal Root Ganglion Neurons. Neuromodulation, 24(4), 639-645. https://doi.org/10.1111/ner.13398
    • Vilaca, A., Sansonetti, M., Fernandes, H., de Windt, L., & Ferreira, L. (2021). Extracellular vesicles as lncRNA-H19 carriers to the cardiovascular system. European Journal of Clinical Investigation, 51, 108-109.
    • Sampaio-Pinto, V., Silva, E. D., Laundos, T. L., Martins, P. D. C., Pinto-do-O, P., & Nascimento, D. S. (2021). Stereological estimation of cardiomyocyte number and proliferation. Methods, 190, 55-62. https://doi.org/10.1016/j.ymeth.2020.06.002
    • Raafs, A. G., Verdonschot, J. A. J., Henkens, M. T. H. M., Adriaans, B. P., Wang, P., Derks, K., Abdul Hamid, M. A., Knackstedt, C., van Empel, V. P. M., Diez, J., Brunner-La Rocca, H-P., Brunner, H. G., Gonzalez, A., Bekkers, S. C. A. M., Heymans, S. R. B., & Hazebroek, M. R. (2021). The combination of carboxy-terminal propeptide of procollagen type I blood levels and late gadolinium enhancement at cardiac magnetic resonance provides additional prognostic information in idiopathic dilated cardiomyopathy - A multilevel assessment of myocardial fibrosis in dilated cardiomyopathy. European journal of heart failure, 23(6), 933-944. https://doi.org/10.1002/ejhf.2201
    • Roblain, Q., Louis, T., Yip, C., Baudin, L., Struman, I., Caolo, V., Lambert, V., Lecomte, J., Noel, A., & Heymans, S. (2021). Intravitreal injection of anti-miRs against miR-142-3p reduces angiogenesis and microglia activation in a mouse model of laser-induced choroidal neovascularization. Aging, 13(9), 12359-12377. https://doi.org/10.18632/aging.203035
    • Glatz, J. F. C., Wang, F., Nabben, M., & Luiken, J. J. F. P. (2021). CD36 as a target for metabolic modulation therapy in cardiac disease. Expert Opinion on Therapeutic Targets, 25(5), 393-400. https://doi.org/10.1080/14728222.2021.1941865
    • Remmelzwaal, S., Beulens, J. W. J., Elders, P. J. M., Stehouwer, C. D. A., Zhang, Z., Handoko, M. L., Appelman, Y., van Empel, V., Heymans, S. R. B., Thijs, L., Staessen, J. A., & van Ballegooijen, A. J. (2021). Sex differences in the longitudinal relationship of low-grade inflammation and echocardiographic measures in the Hoorn and FLEMENGHO Study. PLOS ONE, 16(5), [0251148]. https://doi.org/10.1371/journal.pone.0251148
    • Heggermont, W., Iliodromitis, K., Van Bockstal, K., Backers, J., Lau, C-W., Missiaen, D., De Cooman, J., Timmermans, W., Geelen, P., & De Potter, T. (2021). Clinical symptoms of limited exercise capacity linked to AAI-DDD functionality: An in silico and in vivo approach. Pacing and Clinical Electrophysiology, 44(5), 943-951. https://doi.org/10.1111/pace.14239
    • van Gorp, R. H., Dijkgraaf, I., Bröker, V., Bauwens, M., Leenders, P., Jennen, D., Dweck, M. R., Bucerius, J., Briedé, J. J., van Ryn, J., Brandenburg, V., Mottaghy, F., Spronk, H. M. H., Reutelingsperger, C. P., & Schurgers, L. J. (2021). Off-target effects of oral anticoagulants - vascular effects of vitamin K antagonist and non-vitamin K antagonist oral anticoagulant dabigatran etexilate. Journal of Thrombosis and Haemostasis, 19(5), 1348-1363. https://doi.org/10.1111/jth.15289
    • Simonavicius, J., Mikalauskas, A., & Brunner-La Rocca, H. P. (2021). Soluble CD146-an underreported novel biomarker of congestion: a comment on a review concerning congestion assessment and evaluation in acute heart failure. Heart Failure Reviews, 26(3), 731-732. https://doi.org/10.1007/s10741-020-09950-y
    • Sanders-van Wijk, S., Barandiaran Aizpurua, A., Brunner-La Rocca, H-P., Henkens, M. T. H. M., Weerts, J., Knackstedt, C., Uszko-Lencer, N., Heymans, S., & van Empel, V. (2021). The HFA-PEFF and H2FPEF scores largely disagree in classifying patients with suspected heart failure with preserved ejection fraction. European journal of heart failure, 23(5), 838-840. https://doi.org/10.1002/ejhf.2019
    • Garcia-Pavia, P., Rapezzi, C., Adler, Y., Arad, M., Basso, C., Brucato, A., Burazor, I., Caforio, A. L. P., Damy, T., Eriksson, U., Fontana, M., Gillmore, J. D., Gonzalez-Lopez, E., Grogan, M., Heymans, S., Imazio, M., Kindermann, I., Kristen, A., Maurer, M. S., ... Linhart, A. (2021). Diagnosis and treatment of cardiac amyloidosis: a position statement of the ESC Working Group on Myocardial and Pericardial Diseases. European Heart Journal, 42(16), 1554-1568. https://doi.org/10.1093/eurheartj/ehab072
    • Wong, L., Glatz, J. F. C., Wang, S., Geraets, I. M. E., Vanherle, S., van den Wijngaard, A., Brunner, H., Luiken, J. J. F. P., & Nabben, M. (2021). Comparison of human and rodent cell models to study myocardial lipid-induced insulin resistance. Prostaglandins Leukotrienes and Essential Fatty Acids, 167, [102267]. https://doi.org/10.1016/j.plefa.2021.102267
    • Garcia-Pavia, P., Rapezzi, C., Adler, Y., Arad, M., Basso, C., Brucato, A., Burazor, I., Caforio, A. L. P., Damy, T., Eriksson, U., Fontana, M., Gillmore, J. D., Gonzalez-Lopez, E., Grogan, M., Heymans, S., Imazio, M., Kindermann, I., Kristen, A. V., Maurer, M. S., ... Linhart, A. (2021). Diagnosis and treatment of cardiac amyloidosis. A position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. European journal of heart failure, 23(4), 512-526. https://doi.org/10.1002/ejhf.2140
    • Aizpurua, A. B., Sanders-van Wijk, S., Brunner-La Rocca, H. P., Henkens, M. T. H. M., Weerts, J., Spanjers, M. H. A., Knackstedt, C., & van Empel, V. P. M. (2021). Iron deficiency impacts prognosis but less exercise capacity in heart failure with preserved ejection fraction. Esc heart failure, 8(2), 1304-1313. https://doi.org/10.1002/ehf2.13204
    • Geraets, I. M. E., Coumans, W. A., Strzelecka, A., Schonleitner, P., Antoons, G., Schianchi, F., Willemars, M. M. A., Kapsokalyvas, D., Glatz, J. F. C., Luiken, J. J. F. P., & Nabben, M. (2021). Metabolic Interventions to Prevent Hypertrophy-Induced Alterations in Contractile Properties In Vitro. International journal of molecular sciences, 22(7), [3620]. https://doi.org/10.3390/ijms22073620
    • Sliwa, K., van der Meer, P., Petrie, M. C., Frogoudaki, A., Johnson, M. R., Hilfiker-Kleiner, D., Hamdan, R., Jackson, A. M., Ibrahim, B., Mbakwem, A., Tschoepe, C., Regitz-Zagrosek, V., Omerovic, E., Roos-Hesselink, J., Gatzoulis, M., Tutarel, O., Price, S., Heymans, S., Coats, A. J. S., ... Bauersachs, J. (2021). Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. European journal of heart failure, 23(4), 527-540. https://doi.org/10.1002/ejhf.2133
    • Verhaert, D. V. M., Brunner-La Rocca, H-P., van Veldhuisen, D. J., & Vernooy, K. (2021). The bidirectional interaction between atrial fibrillation and heart failure: consequences for the management of both diseases. EP Europace, 23, 40-45. https://doi.org/10.1093/europace/euaa368
    • Gouweleeuw, L., Wajant, H., Maier, O., Eisel, U. L. M., Blankesteijn, W. M., & Schoemaker, R. G. (2021). Effects of selective TNFR1 inhibition or TNFR2 stimulation, compared to non-selective TNF inhibition, on (neuro)inflammation and behavior after myocardial infarction in male mice. Brain Behavior and Immunity, 93, 156-171. https://doi.org/10.1016/j.bbi.2021.01.001
    • Colpaert, R. M. W., & Calore, M. (2021). Epigenetics and microRNAs in cardiovascular diseases. Genomics, 113(2), 540-551. https://doi.org/10.1016/j.ygeno.2020.12.042
    • Tschoepe, C., Ammirati, E., Bozkurt, B., Caforio, A. L. P., Cooper, L. T., Felix, S. B., Hare, J. M., Heidecker, B., Heymans, S., Huebner, N., Kelle, S., Klingel, K., Maatz, H., Parwani, A. S., Spillmann, F., Starling, R. C., Tsutsui, H., Seferovic, P., & Van Linthout, S. (2021). Myocarditis and inflammatory cardiomyopathy: current evidence and future directions. Nature Reviews Cardiology, 18(3), 169-193. https://doi.org/10.1038/s41569-020-00435-x
    • Dufeys, C., Daskalopoulos, E. P., Castanares-Zapatero, D., Conway, S. J., Ginion, A., Bouzin, C., Ambroise, J., Bearzatto, B., Gala, J. L., Heymans, S., Papageorgiou, A. P., Vinckier, S., Cumps, J., Balligand, J. L., Vanhaverbeke, M., Sinnaeve, P., Janssens, S., Bertrand, L., Beauloye, C., & Horman, S. (2021). AMPKα1 deletion in myofibroblasts exacerbates post-myocardial infarction fibrosis by a connexin 43 mechanism. Basic Research in Cardiology, 116(1), [10]. https://doi.org/10.1007/s00395-021-00846-y
    • Daskalopoulos, E. P., & Blankesteijn, W. M. (2021). Effect of Interventions in WNT Signaling on Healing of Cardiac Injury: A Systematic Review. Cells, 10(2), [207]. https://doi.org/10.3390/cells10020207
    • Hazebroek, M. R., Henkens, M. T. H. M., Raafs, A. G., Verdonschot, J. A. J., Merken, J. J., Dennert, R. M., Eurlings, C., Hamid, M. A. A., Wolffs, P. F. G., Winkens, B., Brunner-La Rocca, H. P., Knackstedt, C., van Paassen, P., van Empel, V. P. M., & Heymans, S. R. B. (2021). Intravenous immunoglobulin therapy in adult patients with idiopathic chronic cardiomyopathy and cardiac parvovirus B19 persistence: a prospective, double-blind, randomized, placebo-controlled clinical trial. European journal of heart failure, 23(2), 302-309. https://doi.org/10.1002/ejhf.2082
    • Simonavicius, J., & Brunner-La Rocca, H. P. (2021). Do chronic heart failure patients receive optimal decongestive interventions in a real‐life setting? Letter regarding the article ‘Association between loop diuretic dose changes and outcomes in chronic heart failure: observations from the ESC‐EORP Heart Failure Long‐Term Registry’. European journal of heart failure, 23(2), 342-342. https://doi.org/10.1002/ejhf.1839
    • Meier, S., Henkens, M., Heymans, S., & Robinson, E. L. (2021). Unlocking the Value of White Blood Cells for Heart Failure Diagnosis. Journal of Cardiovascular Translational Research, 14(1), 53-62. https://doi.org/10.1007/s12265-020-10007-6
    • Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Kaminski, I., Geomini, I., Lemmens, T., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2021). Hypoxia-induced mitochondrial abnormalities in cells of the placenta. PLOS ONE, 16(1), [0245155]. https://doi.org/10.1371/journal.pone.0245155
    • Amier, R. P., Marcks, N., Hooghiemstra, A. M., Nijveldt, R., van Buchem, M. A., de Roos, A., Biessels, G. J., Kappelle, L. J., van Oostenbrugge, R. J., Van der Geest, R. J., Bots, M. L., Greving, J. P., Niessen, W. J., van Osch, M. J. P., de Bresser, J., van de Ven, P. M., Van der Flier, W. M., Rocca, H. P. B. L., van Rossum, A. C., ... Heart-Brain Connection Consortium (2021). Hypertensive Exposure Markers by MRI in Relation to Cerebral Small Vessel Disease and Cognitive Impairment. JACC-Cardiovascular Imaging, 14(1), 176-185. https://doi.org/10.1016/j.jcmg.2020.06.040
    • Cuijpers, I., Papageorgiou, A. P., Carai, P., Herwig, M., Mugge, A., Klein, T., Hamdani, N., Jones, E. A. V., & Heymans, S. (2021). Linagliptin prevents left ventricular stiffening by reducing titin cleavage and hypophosphorylation. Journal of Cellular and Molecular Medicine, 25(2), 729-741. https://doi.org/10.1111/jcmm.16122
    • Zacchigna, S., Paldino, A., Falcao-Pires, I., Daskalopoulos, E. P., Dal Ferro, M., Vodret, S., Lesizza, P., Cannata, A., Miranda-Silva, D., Lourenco, A. P., Pinamonti, B., Sinagra, G., Weinberger, F., Eschenhagen, T., Carrier, L., Kehat, I., Tocchetti, C. G., Russo, M., Ghigo, A., ... Working Group on Myocardial Function of the European Society of Cardiology (2021). Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function. Cardiovascular Research, 117(1), 43-59. https://doi.org/10.1093/cvr/cvaa110
    • Jaarsma, T., Hill, L., Bayes-Genis, A., La Rocca, H-P. B., Castiello, T., Celutkiene, J., Marques-Sule, E., Plymen, C. M., Piper, S. E., Riegel, B., Rutten, F. H., Ben Gal, T., Bauersachs, J., Coats, A. J. S., Chioncel, O., Lopatin, Y., Lund, L. H., Lainscak, M., Moura, B., ... Stromberg, A. (2021). Self-care of heart failure patients: practical management recommendations from the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 23(1), 157-174. https://doi.org/10.1002/ejhf.2008
  • 2020
    • Anker, S. D., Butler, J., Filippatos, G., Khan, M. S., Ferreira, J. P., Bocchi, E., Bohm, M., Brunner-La Rocca, H. P., Choi, D. J., Chopra, V., Chuquiure, E., Giannetti, N., Gomez-Mesa, J. E., Janssens, S., Januzzi, J. L., Gonzalez-Juanatey, J. R., Merkely, B., Nicholls, S. J., Perrone, S. V., ... EMPEROR-Preserved Trial Committees and Investigators (2020). Baseline characteristics of patients with heart failure with preserved ejection fraction in the EMPEROR-Preserved trial. European journal of heart failure, 22(12), 2383-2392. https://doi.org/10.1002/ejhf.2064
    • de Boer, R. A., Hulot, J. S., Tocchetti, C. G., Aboumsallem, J. P., Ameri, P., Anker, S. D., Bauersachs, J., Bertero, E., Coats, A. J. S., Celutkiene, J., Chioncel, O., Dodion, P., Eschenhagen, T., Farmakis, D., Bayes-Genis, A., Jager, D., Jankowska, E. A., Kitsis, R. N., Konety, S. H., ... Backs, J. (2020). Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). European journal of heart failure, 22(12), 2272-2289. https://doi.org/10.1002/ejhf.2029
    • Robinson, E. L., Azodi, M., Heymans, S., & Heggermont, W. (2020). Anthracycline-Related Heart Failure: Certain Knowledge and Open Questions : Where Do we Stand with Chemotherapyinduced Cardiotoxicity?Current Heart Failure Reports, 17(6), 357-364. https://doi.org/10.1007/s11897-020-00489-5
    • Smet, L. M., De Potter, T., & Heggermont, W. A. (2020). Are CHADS(2) and CHA 2DS (2)-VASc of value in risk assessment for new-onset post-operative atrial fibrillation?Intensive and Critical Care Nursing, 61, [102945]. https://doi.org/10.1016/j.iccn.2020.102945
    • Janssen, D. J. A., Ament, S. M. C., Boyne, J., Schols, J. M. G. A., Brunner-La Rocca, H-P., Maessen, J. M. C., & van den Beuken-van Everdingen, M. H. J. (2020). Characteristics for a tool for timely identification of palliative needs in heart failure: The views of Dutch patients, their families and healthcare professionals. European Journal of Cardiovascular Nursing, 19(8), 711-720. [1474515120918962]. https://doi.org/10.1177/1474515120918962
    • Kocken, J. M. M., & da Costa Martins, P. A. (2020). Epigenetic Regulation of Pulmonary Arterial Hypertension-Induced Vascular and Right Ventricular Remodeling: New Opportunities?International journal of molecular sciences, 21(23), [8901]. https://doi.org/10.3390/ijms21238901