• 2023
    • van Mourik, M. J. W., Linz, D., Verwijs, H. J. A., Bekkers, S. C. A. M., Weerts, J., Schotten, U., Rocca, H. B.-L., Lumens, J., Crijns, H. J. G. M., Weijs, B., & Knackstedt, C. (2023). Evaluating subclinical left ventricular and left atrial dysfunction in idiopathic atrial fibrillation: A speckle-tracking based strain-analysis. International Journal of Cardiology, 383(1), 159-165. https://doi.org/10.1016/j.ijcard.2023.04.024
    • Kerkhofs, D., Helgers, R., Hermes, D., Steinbusch, H. P. J., Van Essen, H., Leenders, P., Prickaerts, J., Staals, J., Biessen, E. A., Van Oostenbrugge, R. J., & Foulquier, S. (2023). Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice. Journal of Hypertension, 41(7), 1159-1167. https://doi.org/10.1097/HJH.0000000000003445
    • Rabussier, G., Bunter, I., Bouwhuis, J., Soragni, C., van Zijp, T., Ng, C. P., Domansky, K., Windt, L. J. D., Vulto, P., Murdoch, C. E., Bircsak, K. M., & Lanz, H. L. (2023). Healthy and diseased placental barrier on-a-chip models suitable for standardized studies. Acta Biomaterialia, 164(1), 363-376. https://doi.org/10.1016/j.actbio.2023.04.033
    • Colin, M., Delaitre, C., Foulquier, S., & Dupuis, F. (2023). The AT(1)/AT(2) Receptor Equilibrium Is a Cornerstone of the Regulation of the Renin Angiotensin System beyond the Cardiovascular System. Molecules, 28(14), Article 5481. https://doi.org/10.3390/molecules28145481
    • Stroeks, S. L. V. M., Hellebrekers, D., Claes, G. R. F., Krapels, I. P. C., Henkens, M. H. T. M., Sikking, M., Vanhoutte, E. K., van den Enden, A. T. J. M. H., Brunner, H. G., van den Wijngaard, A., & Verdonschot, J. A. J. (2023). Diagnostic and prognostic relevance of using large gene panels in the genetic testing of patients with dilated cardiomyopathy. European Journal of Human Genetics, 31(7), 776-783. https://doi.org/10.1038/s41431-023-01384-y
    • Aga, Y. S., Radhoe, S. P., Aydin, D., Linssen, G. C. M., Rademaker, P. C., Geerlings, P. R., van Gent, M. W. F., Aksoy, I., Oosterom, L., Brunner-La Rocca, H. P. B. L., van Dalen, B. M., & Brugts, J. J. (2023). Heart failure treatment in patients with and without obesity with an ejection fraction below 50%. European Journal of Clinical Investigation, 53(7), Article e13976. https://doi.org/10.1111/eci.13976
    • Brugts, J. J., Radhoe, S. P., Clephas, P. R. D., Aydin, D., van Gent, M. W. F., Szymanski, M. K., Rienstra, M., van den Heuvel, M. H., da Fonseca, C. A., Linssen, G. C. M., Borleffs, C. J. W., Boersma, E., Asselbergs, F. W., Mosterd, A., Brunner-La Rocca, H. P., de Boer, R. A., Emans, M. E., Beeres, S. L. M. A., Heerebeek, L., ... MONITOR-HF investigators (2023). Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial. Lancet, 401(10394), 2113-2123. https://doi.org/10.1016/S0140-6736(23)00923-6
    • Juni, R. P., Kocken, J. M. M., Abreu, R. C., Ottaviani, L., Davalan, T., Duygu, B., Poels, E. M., Vasilevich, A., Hegenbarth, J. C., Appari, M., Bitsch, N., Olieslagers, S., Schrijvers, D. M., Stoll, M., Heineke, J., de Boer, J., de Windt, L. J., & da Costa, P. A. (2023). MicroRNA-216a is essential for cardiac angiogenesis. Molecular Therapy, 31(6), 1807-1828. https://doi.org/10.1016/j.ymthe.2023.04.007
    • ter Bekke, R. M. A., de Schouwer, K., Conti, S., Claes, G. R. F., Vanoevelen, J., Gommers, S., Helderman-van den Enden, A. T. J. M., & Brunner-LaRocca, H.-P. (2023). Juvenile-onset multifocal atrial arrhythmias, atrial standstill and compound heterozygosity of genetic variants in TAF1A: sentinel event for evolving dilated cardiomyopathy-a case report. European Heart Journal - Case Reports, 7(6), Article ytad255. https://doi.org/10.1093/ehjcr/ytad255
    • Callewaert, B., Gsell, W., Himmelreich, U., & Jones, E. A. V. (2023). Q-VAT: Quantitative Vascular Analysis Tool. Frontiers in Cardiovascular Medicine, 10, Article 1147462. https://doi.org/10.3389/fcvm.2023.1147462
    • Sikking, M. A., Stroeks, S. L. V. M., Henkens, M. T. H. M., Venner, M. F. G. H. M., Li, X., Heymans, S. R. B., Hazebroek, M. R., & Verdonschot, J. A. J. (2023). Cardiac Inflammation in Adult-Onset Genetic Dilated Cardiomyopathy. Journal of Clinical Medicine, 12(12), Article 3937. https://doi.org/10.3390/jcm12123937
    • Steiner, B., Neumann, A., Pelz, Y., Ski, C. F., Hill, L., Thompson, D. R., Fitzsimons, D., Dixon, L. J., Brandts, J., Verket, M., Schuett, K., Eurlings, C. G. M. J., Boyne, J. J. J., Gingele, A. J., De Maesschalck, L., Murphy, M., da Luz, E. F., Barrett, M., Windle, K., ... PASSION-HF consortium (2023). Challenges in heart failure care in four European countries: a comparative study. European Journal of Public Health, 33(3), 448-454. https://doi.org/10.1093/eurpub/ckad059
    • Linders, A. N., Dias, I. B., Ovchinnikova, E. S., Vermeer, M. C. S. C., Hoes, M. F., Mavrogenis, G. M., Deiman, F. E., Gomez, K. F. A., Bliley, J. M., Nehme, J., Vink, A., Gietema, J., de Boer, R. A., Westenbrink, D., Sillje, H. H. W., Hilfiker-Kleiner, D., van Laake, L. W., Feinberg, A. W., Demaria, M., ... van der Meer, P. (2023). Evaluation of Senescence and Its Prevention in Doxorubicin-Induced Cardiotoxicity Using Dynamic Engineered Heart Tissues. JACC: CardioOncology, 5(3), 298-315. https://doi.org/10.1016/j.jaccao.2023.03.012
    • Stroeks, S. L. V. M., & Verdonschot, J. A. J. (2023). The next step toward personalized recommendations for genetic cardiomyopathies. European Journal of Human Genetics, 31(11), 1201 - 1203. https://doi.org/10.1038/s41431-023-01394-w
    • Gorter, T. M., van Veldhuisen, D. J., Mulder, B. A., Arita, V. A. A. A., van Empel, V. P. M., Manintveld, O. C., Tieleman, R. G., Maass, A. H., Vernooy, K., van Gelder, I. C., & Rienstra, M. (2023). Prevalence and Incidence of Atrial Fibrillation in Heart Failure with Mildly Reduced or Preserved Ejection Fraction: (Additive) Value of Implantable Loop Recorders. Journal of Clinical Medicine, 12(11), Article 3682. https://doi.org/10.3390/jcm12113682
    • Vermeer, M. C. S. C., Arevalo Gomez, K. F., Hoes, M. F., Tromp, J., Verdonschot, J. A. J., Henkens, M. T. H. M., Silljé, H. H. W., Bolling, M. C., & van der Meer, P. (2023). Clinical Outcome in KLHL24 Cardiomyopathy. Circulation: Genomic and Precision Medicine, 16(4), 401-403. https://doi.org/10.1161/CIRCGEN.122.003998
    • Calore, M., Compagno, S., Vencato, S., Colpaert, R., Sacchetto, C., Lorenzon, A., Becchi, T., Facchinello, N., Romualdi, C., de Windt, L., Braghetta, P., Vitiello, L., & Rampazzo, A. (2023). Heart transcriptome profile of a novel transgenic mouse model for arrhythmogenic cardiomyopathy. European Journal of Human Genetics, 31, 404-404. https://doi.org/10.1038/s41431-023-01338-4
    • Kerstens, T. P., Weerts, J., van Dijk, A. P. J., Weijers, G., Knackstedt, C., Eijsvogels, T. M. H., Oxborough, D., van Empel, V. P. M., & Thijssen, D. H. J. (2023). Left ventricular strain-volume loops and diastolic dysfunction in suspected heart failure with preserved ejection fraction. International Journal of Cardiology, 378(1), 144-150. https://doi.org/10.1016/j.ijcard.2023.01.084
    • Girerd, N., Levy, D., Duarte, K., Ferreira, J. P., Ballantyne, C., Collier, T., Pizard, A., Björkman, J., Butler, J., Clark, A., Cleland, J. G., Delles, C., Diez, J., González, A., Hazebroek, M., Ho, J., Huby, A. C., Hwang, S. J., Latini, R., ... Zannad, F. (2023). Protein Biomarkers of New-Onset Heart Failure: Insights From the Heart Omics and Ageing Cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. Circulation-Heart Failure, 16(5), 426-441. Article e009694. https://doi.org/10.1161/CIRCHEARTFAILURE.122.009694
    • Knackstedt, C., Schummers, G., Schroder, J., Marx, N., Lumens, J., Sanders-van Wijk, S., Ramaekers, B., Becker, M., van Empel, V., Brunner-La Rocca, H. P., & PsychEcho study group (2023). A graphical analysis of aspects contributing to the spreading of measurements of left ventricular function. International Journal of Cardiovascular Imaging, 39(5), 915-927. https://doi.org/10.1007/s10554-023-02796-z
    • Starmans, N. L., Wolters, F. J., Leeuwis, A. E., Bron, E. E., La Rocca, H. P. B., Staals, J., Biessels, G. J., & Kappelle, L. J. (2023). Twenty-four hour blood pressure variability and the prevalence and the progression of cerebral white matter hyperintensities. Journal of Cerebral Blood Flow and Metabolism, 43(5), 801-811. https://doi.org/10.1177/0271678X221149937
    • Verdonschot, J. A. J., Wang, P., Derks, K. W. J., Adriaens, M. E., Stroeks, S. L. V. M., Henkens, M. T. H. M., Raafs, A. G., Sikking, M., de Koning, B., van den Wijngaard, A., Krapels, I. P. C., Nabben, M., Brunner, H. G., & Heymans, S. R. B. (2023). Clustering of Cardiac Transcriptome Profiles Reveals Unique Subgroups of Dilated Cardiomyopathy Patients. JACC: Basic to Translational Science, 8(4), 406-418. https://doi.org/10.1016/j.jacbts.2022.10.010
    • Strand, M. E., Vanhaverbeke, M., Henkens, M. T. H. M., Sikking, M. A., Rypdal, K. B., Braathen, B., Almaas, V. M., Tonnessen, T., Christensen, G., Heymans, S., & Lunde, I. G. (2023). Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease. Biomedicines, 11(4), Article 1066. https://doi.org/10.3390/biomedicines11041066
    • Stroeks, S. L. V. M., Lunde, I. G. G., Hellebrekers, D. M. E. I., Claes, G. R. F., Wakimoto, H., Gorham, J., Krapels, I. P. C., Vanhoutte, E. K. K., van den Wijngaard, A., Henkens, M. T. H. M., Raafs, A. G. G., Sikking, M. A. A., Broers, J. L. V., Nabben, M., Jones, E. A. V., Heymans, S. R. B., Brunner, H. G. G., & Verdonschot, J. A. J. (2023). Prevalence and Clinical Consequences of Multiple Pathogenic Variants in Dilated Cardiomyopathy. Circulation: Genomic and Precision Medicine, 16(2), Article e003788. https://doi.org/10.1161/CIRCGEN.122.003788
    • Clephas, P. R. D., Radhoe, S. P., Linssen, G. C. M., Langerveld, J., Plomp, J., Smits, J. P. P., Nagelsmit, M. J., Rocca, H. P. B. L., & Brugts, J. J. (2023). Serum potassium level and mineralocorticoid receptor antagonist dose in a large cohort of chronic heart failure patients. Esc heart failure, 10(2), 1481-1487. https://doi.org/10.1002/ehf2.14285
    • Soragni, C., Vergroesen, T., Hettema, N., Rabussier, G., Lanz, H. L., Trietsch, S. J., de Windt, L. J., & Ng, C. P. (2023). Quantify permeability using on-a-chip models in high-throughput applications. STAR protocols, 4(1), Article 102051. https://doi.org/10.1016/j.xpro.2023.102051
    • Ferreira, J. P., Cleland, J. G. F., Girerd, N., Pellicori, P., Hazebroek, M. R., Verdonschot, J., Collier, T. J., Petutschnigg, J., Clark, A. L., Staessen, J. A., Heymans, S., Rossignol, P., & Zannad, F. (2023). Effect of Spironolactone on QRS Duration in Patients at Risk for Heart Failure (from the HOMAGE Trial). American Journal of Cardiology, 191(1), 39-42. https://doi.org/10.1016/j.amjcard.2022.12.016
    • Robinson, E. L., Ameri, P., Delrue, L., Vanderheyden, M., Bartunek, J., Altieri, P., Heymans, S., & Heggermont, W. A. (2023). Differential expression of epigenetic modifiers in early and late cardiotoxic heart failure reveals DNA methylation as a key regulator of cardiotoxicity. Frontiers in Cardiovascular Medicine, 10(1), Article 884174. https://doi.org/10.3389/fcvm.2023.884174
    • Radhoe, S. P., Clephas, P. R. D., Linssen, G. C. M., Oortman, R. M., Smeele, F. J., Van Drimmelen, A. A., Schaafsma, H. J., Westendorp, P. H., Rocca, H. P. B. L., & Brugts, J. J. (2023). Phenotypic patient profiling for improved implementation of guideline-directed medical therapy: An exploratory analysis in a large real-world chronic heart failure cohort. Frontiers in Pharmacology, 14(1), Article 1081579. https://doi.org/10.3389/fphar.2023.1081579
    • de Boer, M., Hekkert, M. T., Chang, J., van Thiel, B. S., Martens, L., Bos, M. M., de Kleijnen, M. G. J., Ridwan, Y., Octavia, Y., van Deel, E. D., Blonden, L. A., Brandt, R. M. C., Barnhoorn, S., Bautista-Nino, P. K., Krabbendam-Peters, I., Wolswinkel, R., Arshi, B., Ghanbari, M., Kupatt, C., ... Duncker, D. J. (2023). DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice. Aging Cell, 22(3), Article e13768. https://doi.org/10.1111/acel.13768
    • Sanchez-Aguilera, P., Lopez-Crisosto, C., Norambuena-Soto, I., Penannen, C., Zhu, J. M., Bomer, N., Hoes, M. F., van der Meer, P., Chiong, M., Westenbrink, B. D., & Lavandero, S. (2023). IGF-1 boosts mitochondrial function by a Ca2+ uptake-dependent mechanism in cultured human and rat cardiomyocytes. Frontiers in physiology, 14(1), Article 1106662. https://doi.org/10.3389/fphys.2023.1106662
    • Stroeks, S. L. V. M., van Beek, D., Adriaens, M. E., & Verdonschot, J. A. J. (2023). Titin Allelic Expression and Protein Processing Pathways in Early-Stage Dilated Cardiomyopathy Patients With Truncating Titin Variants. Circulation: Genomic and Precision Medicine, 16(1), 90-91. Article e003901. https://doi.org/10.1161/circgen.122.003901
    • Ferreira, J. P., Cleland, J. G. F., Girerd, N., Pellicori, P., Hazebroek, M. R., Verdonschot, J., Collier, T. J., Petutschnigg, J., Clark, A. L., Staessen, J. A., Heymans, S., Zannad, F., & Rossignol, P. (2023). Early and late renal function changes with spironolactone in patients at risk of developing heart failure: findings from the HOMAGE trial. Clinical research in cardiology, 112(2), 330-332. https://doi.org/10.1007/s00392-022-02116-w
    • Nuzzi, V., Raafs, A., Manca, P., Henkens, M. T. H. M., Gregorio, C., Boscutti, A., Verdonschot, J., Hazebroek, M., Knackstedt, C., Merlo, M., Stolfo, D., Sinagra, G., & Heymans, S. R. B. (2023). Left Atrial Reverse Remodeling in Dilated Cardiomyopathy. Journal of the American Society of Echocardiography, 36(2), 154-162. https://doi.org/10.1016/j.echo.2022.10.017
    • Luo, H., Weerts, J., Bekkers, A., Achten, A., Lievens, S., Smeets, K., van Empel, V., Delhaas, T., & Prinzen, F. W. (2023). Association between phonocardiography and echocardiography in heart failure patients with preserved ejection fraction. European Heart Journal - Digital Health, 4(1), 4-11. https://doi.org/10.1093/ehjdh/ztac073
    • van Beek, D., Verdonschot, J., Derks, K., Brunner, H., de Kok, T., Arts, I., Heymans, S., Kutmon, M., & Adriaens, M. (2023). Allele-specific expression analysis for complex genetic phenotypes applied to a unique dilated cardiomyopathy cohort. Scientific Reports, 13(1), Article 564. https://doi.org/10.1038/s41598-023-27591-7
    • Rohr, M., Brandenburg, V., & Rocca, H. P. B. (2023). How to diagnose iron deficiency in chronic disease: A review of current methods and potential marker for the outcome. European Journal of Medical Research, 28(1), Article 15. https://doi.org/10.1186/s40001-022-00922-6
    • Scherrenberg, M., Leenen, J. P. L., van der Velde, A. E., Boyne, J., Bruins, W., Vranken, J., Brunner-La Rocca, H. P., De Kluiver, E. P., & Dendale, P. (2023). Bringing the hospital to home: Patient-reported outcome measures of a digital health-supported home hospitalisation platform to support hospital care at home for heart failure patients. Digital health, 9(1), 1-10. Article 20552076231152178. https://doi.org/10.1177/20552076231152178
    • van Nieuwenhoven, F. A., Schroen, B., Barile, L., van Middendorp, L., Prinzen, F. W., & Auricchio, A. (2023). Plasma Extracellular Vesicles as Liquid Biopsy to Unravel the Molecular Mechanisms of Cardiac Reverse Remodeling Following Resynchronization Therapy?Journal of Clinical Medicine, 12(2), Article 665. https://doi.org/10.3390/jcm12020665
    • Gürgöze, M. T., van Vark, L. C., Baart, S. J., Kardys, I., Akkerhuis, K. M., Manintveld, O. C., Postmus, D., Hillege, H. L., Lesman-Leegte, I., Asselbergs, F. W., Brunner-la-Rocca, H.-P., van den Bos, E. J., Orsel, J. G., de Ridder, S. P. J., Pinto, Y. M., & Boersma, E. (2023). Multimarker Analysis of Serially Measured GDF-15, NT-proBNP, ST2, GAL-3, cTnI, Creatinine, and Prognosis in Acute Heart Failure. Circulation-Heart Failure, 16(1), Article e009526. https://doi.org/10.1161/CIRCHEARTFAILURE.122.009526
    • Timmermans, E. J., Leeuwis, A. E., Bots, M. L., van Alphen, J. L., Biessels, G. J., Brunner-La Rocca, H.-P., Kappelle, L. J., van Rossum, A. C., van Osch, M. J. P., Vaartjes, I., & Heart-Brain Connection Consortium (2023). Neighbourhood walkability in relation to cognitive functioning in patients with disorders along the heart-brain axis. Health & Place, 79(1), Article 102956. https://doi.org/10.1016/j.healthplace.2022.102956
    • Vilaça, A., de Windt, L. J., Fernandes, H., & Ferreira, L. (2023). Strategies and challenges for non-viral delivery of non-coding RNAs to the heart. Trends in Molecular Medicine, 29(1), 70-91. https://doi.org/10.1016/j.molmed.2022.10.002
    • Henkens, M. T. H. M., van Ast, J. F., te Riele, A. S. J. M., Houweling, A. C., Amin, A. S., Nijveldt, R., Antoni, M. L., Li, X., Wehrens, S. M. T., von der Thusen, J. H., Damman, K., ter Horst, E. N., Manintveld, O. C., Abma-Schouten, R. Y., Niessen, H. W. M., Sillje, H. H. W., Jukema, J. W., & Doevendans, P. A. (2023). The Netherlands Heart Tissue Bank Strengthening the cardiovascular research infrastructure with an open access Cardiac Tissue Repository. Netherlands Heart Journal, 31(1), 16-20. https://doi.org/10.1007/s12471-022-01713-8
    • Baldewijns, K., Boyne, J., Rohde, C., de Maesschalck, L., Devillé, A., Brandenburg, V., De Bleser, L., Derickx, M., Bektas, S., & Brunner-La Rocca, H.-P. (2023). What kind of patient education and self-care support do patients with heart failure receive, and by whom? Implementation of the ESC guidelines for heart failure in three European regions. Heart & Lung, 57(1), 25-30. https://doi.org/10.1016/j.hrtlng.2022.07.013
  • 2022
    • Hegenbarth, J. C., De Majo, F., Spano, G., Olieslagers, S., Esfandyari, D., Tiburcy, M., Zimmermann, W. H., Stoll, M., & de Windt, L. (2022). Machine learning-assisted integration of single cell transcriptomic data identifies potential cardiomyocyte maturation genes. Journal of Molecular and Cellular Cardiology, 173, S47-S47. https://doi.org/10.1016/j.yjmcc.2022.08.094
    • Spano, G., Hegenbarth, J. C., De Majo, F., Tiburcy, M., Zimmermann, W. H., & de Windt, L. (2022). RNA m6A modification governs early human cardiomyocyte commitment. Journal of Molecular and Cellular Cardiology, 173, S108-S109. https://doi.org/10.1016/j.yjmcc.2022.08.215
    • Rypdal, K. B., Olav Melleby, A., Robinson, E. L., Li, J., Palmero, S., Seifert, D. E., Martin, D., Clark, C., López, B., Andreassen, K., Dahl, C. P., Sjaastad, I., Tønnessen, T., Stokke, M. K., Louch, W. E., González, A., Heymans, S., Christensen, G., Apte, S. S., & Lunde, I. G. (2022). ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload. Communications Biology, 5(1), Article 1392. https://doi.org/10.1038/s42003-022-04361-1
    • Fanti, S., Stephenson, E., Rocha-Vieira, E., Protonotarios, A., Kanoni, S., Shahaj, E., Paula Longhi, M., Vyas, V. S., Dyer, C., Pontarini, E., Asimaki, A., Bueno-Beti, C., De Gaspari, M., Rizzo, S., Basso, C., Bombardieri, M., Coe, D., Wang, G., Harding, D., ... Marelli-Berg, F. M. (2022). Circulating c-Met-Expressing Memory T Cells Define Cardiac Autoimmunity. Circulation, 146(25), 1930-1945. https://doi.org/10.1161/CIRCULATIONAHA.121.055610
    • Hurkmans, E. G. E., Brand, A. C. A. M., Verdonschot, J. A. J., Te Loo, D. M. W. M., & Coenen, M. J. H. (2022). Pharmacogenetics of chemotherapy treatment response and -toxicities in patients with osteosarcoma: a systematic review. BMC Cancer, 22(1), 1326. Article 1326. https://doi.org/10.1186/s12885-022-10434-5
    • van der Velden, J., Asselbergs, F. W., Bakkers, J., Batkai, S., Bertrand, L., Bezzina, C. R., Bot, I., Brundel, B., Carrier, L., Chamuleau, S., Ciccarelli, M., Dawson, D., Davidson, S. M., Dendorfer, A., Duncker, D. J., Eschenhagen, T., Fabritz, L., Falcão-Pires, I., Ferdinandy, P., ... Thum, T. (2022). Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart. Cardiovascular Research, 118(15), 3016-3051. https://doi.org/10.1093/cvr/cvab370