Publications
- 2014
- Eurlings, L. W., Sanders-van Wijk, S., van Kraaij, D. J. W., van Kimmenade, R., Meeder, J. G., Kamp, O., van Dieijen-Visser, M. P., Tijssen, J. G. P., Brunner-La Rocca, H.-P., & Pinto, Y. M. (2014). Risk stratification with the use of serial N-terminal pro-B-type natriuretic peptide measurements during admission and early after discharge in heart failure patients: post hoc analysis of the PRIMA study. Journal of Cardiac Failure, 20(12), 881-90. https://doi.org/10.1016/j.cardfail.2014.08.014
- Reinhardt, B., Godfrey, R., Fellbrich, G., Frank, H., Lueske, A., Olieslagers, S., Mertens, T., & Waltenberger, J. (2014). Human cytomegalovirus infection impairs endothelial cell chemotaxis by disturbing VEGF signalling and actin polymerization. Cardiovascular Research, 104(2), 315-325. https://doi.org/10.1093/cvr/cvu204
- Skobel, E., Martinez-Romero, A., Scheibe, B., Schauerte, P., Marx, N., Luprano, J., & Knackstedt, C. (2014). Evaluation of a newly designed shirt-based ECG and breathing sensor for home-based training as part of cardiac rehabilitation for coronary artery disease. European Journal of Preventive Cardiology, 21(11), 1332-1340. https://doi.org/10.1177/2047487313493227
- Nabben, M., van Bree, B. W., Lenaers, E., Hoeks, J., Hesselink, M. K., Schaart, G., Gijbels, M. J., Glatz, J. F., da Silva, G. J., De Windt, L. J., Tian, R., Mike, E., Skapura, D. G., Wehrens, X. H., & Schrauwen, P. (2014). Lack of UCP3 does not affect skeletal muscle mitochondrial function under lipid-challenged conditions, but leads to sudden cardiac death.Basic Research in Cardiology, 109(6), Article 447. https://doi.org/10.1007/s00395-014-0447-4
- Kaye, D. M., Mariani, J. A., van Empel, V., & Maeder, M. T. (2014). Determinants and implications of elevated soluble ST2 levels in heart failure. International Journal of Cardiology, 176(3), 1242-3. https://doi.org/10.1016/j.ijcard.2014.07.206
- Elliott, P. M., Anastasakis, A., Borger, M. A., Borggrefe, M., Cecchi, F., Charron, P., Hagege, A. A., Lafont, A., Limongelli, G., Mahrholdt, H., McKenna, W. J., Mogensen, J., Nihoyannopoulos, P., Nistri, S., Pieper, P. G., Pieske, B., Rapezzi, C., Rutten, F. H., Tillmanns, C., ... Watkins, H. (2014). 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy The Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC). European Heart Journal, 35(39), 2733-2779. https://doi.org/10.1093/eurheartj/ehu284
- Tijsen, A. J., van der Made, I., van den Hoogenhof, M. M., Wijnen, W. J., van Deel, E. D., de Groot, N. E., Alekseev, S., Fluiter, K., Schroen, B., Goumans, M.-J., van der Velden, J., Duncker, D. J., Pinto, Y. M., & Creemers, E. E. (2014). The microRNA-15 family inhibits the TGF beta-pathway in the heart. Cardiovascular Research, 104(1), 61-71. https://doi.org/10.1093/cvr/cvu184
- Abdurrachim, D., Ciapaite, J., Wessels, B., Nabben, M., Luiken, J. J. F. P., Nicolay, K., & Prompers, J. J. (2014). Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1841(10), 1525-1537. https://doi.org/10.1016/j.bbalip.2014.07.016
- Jacobs, L., Thijs, L., Jin, Y., Zannad, F., Mebazaa, A., Rouet, P., Pinet, F., Bauters, C., Pieske, B., Tomaschitz, A., Mamas, M., Diez, J., McDonald, K., Cleland, J. G. F., Brunner-La Rocca, H.-P., Heymans, S., Latini, R., Masson, S., Sever, P., ... Staessen, J. A. (2014). Heart 'omics' in AGEing (HOMAGE): design, research objectives and characteristics of the common database. Journal of Biomedical Research, 28(5), 349-59. https://doi.org/10.7555/JBR.28.20140045
- Kapsokalyvas, D., Schiffers, P. M. H., Maij, N., Suylen, D. P., Hackeng, T. M., van Zandvoort, M. A. M. J., & De Mey, J. G. R. (2014). Imaging evidence for endothelin ETA/ETB receptor heterodimers in isolated rat mesenteric resistance arteries. Life Sciences, 111(1-2), 36-41. https://doi.org/10.1016/j.lfs.2014.07.007
- Westermann, D., & Heymans, S. (2014). Fibrosis or hypertrophy: let TIMPs decide. Cardiovascular Research, 103(2), 196-197. https://doi.org/10.1093/cvr/cvu160
- Altara, R., Manca, M., Hessel, M. H. M., Janssen, B. J., Struijker-Boudier, H. H. A., Hermans, R. J. J., & Blankesteijn, M. (2014). Improving membrane based multiplex immunoassays for semi-quantitative detection of multiple cytokines in a single sample. BMC Biotechnology, 14, Article 63. https://doi.org/10.1186/1472-6750-14-63
- Martins, P. A. D. C., Leptidis, S., & De Windt, L. J. (2014). Nuclear Calcium Transients Hermes Propylaios in the Heart. Circulation, 130(3), 221-223. https://doi.org/10.1161/CIRCULATIONAHA.114.010675
- van Empel, V. P. M., Kaye, D. M., & Borlaug, B. A. (2014). Effects of Healthy Aging on the Cardiopulmonary Hemodynamic Response to Exercise. American Journal of Cardiology, 114(1), 131-135. https://doi.org/10.1016/j.amjcard.2014.04.011
- Prahst, C., Kasaai, B., Moraes, F., Jahnsen, E. D., Larrivee, B., Villegas, D., Pardanaud, L., Pibouin-Fragner, L., Zhang, F., Zaun, H. C., Eichmann, A., & Jones, E. A. V. (2014). The H2.0-like homeobox transcription factor modulates yolk sac vascular remodeling in mouse embryos. Arteriosclerosis Thrombosis and Vascular Biology, 34(7), 1468-76. https://doi.org/10.1161/ATVBAHA.114.303626
- Murdoch, C. E., Chaubey, S., Zeng, L., Yu, B., Ivetic, A., Walker, S. J., Vanhoutte, D., Heymans, S., Grieve, D. J., Cave, A. C., Brewer, A. C., Zhang, M., & Shah, A. M. (2014). Endothelial NADPH Oxidase-2 Promotes Interstitial Cardiac Fibrosis and Diastolic Dysfunction Through Proinflammatory Effects and Endothelial-Mesenchymal Transition. Journal of the American College of Cardiology, 63(24), 2734-2741. https://doi.org/10.1016/j.jacc.2014.02.572
- Troughton, R. W., Frampton, C. M., Brunner-La Rocca, H.-P., Pfisterer, M., Eurlings, L. W. M., Erntell, H., Persson, H., O'Connor, C. M., Moertl, D., Karlstrom, P., Dahlstrom, U., Gaggin, H. K., Januzzi, J. L., Berger, R., Richards, A. M., Pinto, Y. M., & Nicholls, M. G. (2014). Effect of B-type natriuretic peptide-guided treatment of chronic heart failure on total mortality and hospitalization: an individual patient meta-analysis. European Heart Journal, 35(23), 1559-1567. https://doi.org/10.1093/eurheartj/ehu090
- Peters, T., & Schroen, B. (2014). Missing links in cardiology: long non-coding RNAs enter the arena. Pflugers Archiv-European Journal of Physiology, 466(6), 1177-1187. https://doi.org/10.1007/s00424-014-1479-1
- Bekkers, S. C. A. M., & Brunner-La Rocca, H. P. (2014). Elderly primary care hypertension patients-who to refer for echocardiography?Netherlands Heart Journal, 22(5), 231-233. https://doi.org/10.1007/s12471-014-0550-z
- Leite-Moreira, A. F., Lourenco, A. P., Balligand, J.-L., Bauersachs, J., Clerk, A., De Windt, L. J., Heymans, S., Hilfiker-Kleiner, D., Hirsch, E., Iaccarino, G., Kaminski, K. A., Knoell, R., Mayr, M., Tarone, G., Thum, T., & Tocchetti, C. G. (2014). ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models. European journal of heart failure, 16(5), 509-518. https://doi.org/10.1002/ejhf.66
- Tarone, G., Balligand, J.-L., Bauersachs, J., Clerk, A., De Windt, L., Heymans, S., Hilfiker-Kleiner, D., Hirsch, E., Iaccarino, G., Knoell, R., Leite-Moreira, A. F., Lourenco, A. P., Mayr, M., Thum, T., & Tocchetti, C. G. (2014). Targeting myocardial remodelling to develop novel therapies for heart failure A position paper from the Working Group on Myocardial Function of the European Society of Cardiology. European journal of heart failure, 16(5), 494-508. https://doi.org/10.1002/ejhf.62
- Poels, E. M., Bitsch, N., Slenter, J. M., Kooi, M. E., de Theije, C. C., De Windt, L. J., van Empel, V. P., & da Costa Martins, P. A. (2014). Supplementing exposure to hypoxia with a copper depleted diet does not exacerbate right ventricular remodeling in mice. PLOS ONE, 9(4), Article 92983. https://doi.org/10.1371/journal.pone.0092983
- Kriemler, S., Buergi, F., Wick, C., Wick, B., Keller, M., Wiget, U., Schindler, C., Kaufmann, B. A., Kohler, M., Bloch, K., & Brunner-La Rocca, H.-P. (2014). Prevalence of Acute Mountain Sickness at 3500 m Within and Between Families: A Prospective Cohort Study. High Altitude Medicine & Biology, 15(1), 28-38. https://doi.org/10.1089/ham.2013.1073
- Daskalopoulos, E. P., Hermans, K. C. M., & Blankesteijn, M. (2014). Cardiac (myo)fibroblast: Novel Strategies for its Targeting Following Myocardial Infarction. Current Pharmaceutical Design, 20(12), 1987-2002. https://doi.org/10.2174/13816128113199990452
- Beaumont, J., Lopez, B., Hermida, N., Schroen, B., Jose, G. S., Heymans, S., Valencia, F., Jose Gomez-Doblas, J., De Teresa, E., Diez, J., & Gonzalez, A. (2014). microRNA-122 down-regulation may play a role in severe myocardial fibrosis in human aortic stenosis through TGF-beta(1) up-regulation. Clinical Science, 126(7-8), 497-506. https://doi.org/10.1042/CS20130538
- Hendriks, J. M. L., Vrijhoef, H. J. M., Crijns, H. J. G. M., & Brunner-La Rocca, H. P. (2014). The effect of a nurse-led integrated chronic care approach on quality of life in patients with atrial fibrillation. EP Europace, 16(4), 491-499. https://doi.org/10.1093/europace/eut286
- Sanders-van Wijk, S., van Empel, V., Knackstedt, C., & Brunner-La Rocca, H.-P. (2014). Heart failure and COPD: Time to SHIFT?International Journal of Cardiology, 172(2), 293-294. https://doi.org/10.1016/j.ijcard.2013.12.285
- Roncarati, R., Anselmi, C. V., Losi, M. A., Papa, L., Cavarretta, E., Martins, P. D. C., Contaldi, C., Jotti, G. S., Franzone, A., Galastri, L., Latronico, M. V. G., Imbriaco, M., Esposito, G., De Windt, L., Betocchi, S., & Condorelli, G. (2014). Circulating miR-29a, Among Other Up-Regulated MicroRNAs, Is the Only Biomarker for Both Hypertrophy and Fibrosis in Patients With Hypertrophic Cardiomyopathy. Journal of the American College of Cardiology, 63(9), 920-927. https://doi.org/10.1016/j.jacc.2013.09.041
- Papageorgiou, A.-P., & Heymans, S. (2014). Peroxidasin-like protein: expanding the horizons of matrix biology. Cardiovascular Research, 101(3), 342-343. https://doi.org/10.1093/cvr/cvu017
- Peeters, J. M. P. W. U., Sanders-van Wijk, S., Bektas, S., Knackstedt, C., Rickenbacher, P., Nietlispach, F., Handschin, R., Maeder, M. T., Muzzarelli, S. F., Pfisterer, M. E., & Brunner-La Rocca, H. P. (2014). Biomarkers in outpatient heart failure management; Are they correlated to and do they influence clinical judgment?Netherlands Heart Journal, 22(3), 115-121. https://doi.org/10.1007/s12471-013-0503-y
- van Empel, V. P. M., Lee, J., Williams, T. J., & Kaye, D. M. (2014). Iron deficiency in patients with idiopathic pulmonary arterial hypertension. Heart Lung and Circulation, 23(3), 287-92. https://doi.org/10.1016/j.hlc.2013.08.007
- Rienks, M., Papageorgiou, A.-P., Frangogiannis, N. G., & Heymans, S. (2014). Myocardial Extracellular Matrix An Ever-Changing and Diverse Entity. Circulation Research, 114(5), 872-888. https://doi.org/10.1161/CIRCRESAHA.114.302533
- Meyer, U., Schindler, C., Zahner, L., Ernst, D., Hebestreit, H., van Mechelen, W., Rocca, H.-P. B.-L., Probst-Hensch, N., Puder, J. J., & Kriemler, S. (2014). Long-Term Effect of a School-Based Physical Activity Program (KISS) on Fitness and Adiposity in Children: A Cluster-Randomized Controlled Trial. PLOS ONE, 9(2), Article e87929. https://doi.org/10.1371/journal.pone.0087929
- Hazebroek, M. R., Everaerts, K., & Heymans, S. (2014). Diagnostic approach of myocarditis: strike the golden mean. Netherlands Heart Journal, 22(2), 80-84. https://doi.org/10.1007/s12471-013-0499-3
- Van Empel, V. P. M., Kaufmann, B. A., Bernheim, A. M., Goetschalckx, K., Min, S. Y., Muzzarelli, S., Pfisterer, M. E., Kiencke, S., Maeder, M. T., & Brunner-La Rocca, H.-P. (2014). Interaction Between Pulmonary Hypertension and Diastolic Dysfunction in an Elderly Heart Failure Population. Journal of Cardiac Failure, 20(2), 98-104. https://doi.org/10.1016/j.cardfail.2013.12.010
- Burkard, T., Pfister, O., Rickli, H., Follath, F., Hack, D., Zaker, R., Pittl, U., Handschin, R., Pfisterer, M., & Brunner-La Rocca, H. .-P. (2014). Prognostic impact of systemic inflammatory diseases in elderly patients with congestive heart failure. QJM: An International Journal of Medicine, 107(2), 131-138. https://doi.org/10.1093/qjmed/hct205
- Napp, A., Joosten, S., Stunder, D., Knackstedt, C., Zink, M., Bellmann, B., Marx, N., Schauerte, P., & Silny, J. (2014). Electromagnetic Interference With Implantable Cardioverter-Defibrillators at Power Frequency An In Vivo Study. Circulation, 129(4), 441-450. https://doi.org/10.1161/CIRCULATIONAHA.113.003081
- Hazebroek, M. R., van Paassen, P., Weerwind, P. W., Cooper, L. T. . J., Uriel, N., Caliskan, K., de Vries, B., Maessen, J. G., Autschbach, R., Heymans, S., & Donker, D. W. (2014). A passionate endurance cyclist ultimately survives sudden death in right ventricular giant cell myocarditis. International Journal of Cardiology, 170(3), E74-E75. https://doi.org/10.1016/j.ijcard.2013.11.028
- Sanders-van Wijk, S., Maeder, M. T., Nietlispach, F., Rickli, H., Estlinbaum, W., Erne, P., Rickenbacher, P., Peter, M., Pfisterer, M. P., & Brunner-La Rocca, H.-P. (2014). Long-Term Results of Intensified, N-Terminal-Pro-B-Type Natriuretic Peptide-Guided Versus Symptom-Guided Treatment in Elderly Patients With Heart Failure Five-Year Follow-Up From TIME-CHF. Circulation-Heart Failure, 7(1), 131-139. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000527
- Hohl, M., Ardehali, H., Azuaje, F. J., Breckenridge, R. A., Doehner, W., Eaton, P., Ehret, G. B., Fujita, T., Gaetani, R., Giacca, M., Hasenfuss, G., Heymans, S., Leite-Moreira, A. F., Linke, W. A., Linz, D., Lyon, A., Mamas, M. A., Oresic, M., Papp, Z., ... Maack, C. (2014). Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research. European journal of heart failure, 16(1), 6-14. https://doi.org/10.1002/ejhf.10
- Mafi Rad, M., Blaauw, Y., Debie, L., Brunner-La Rocca, H., & Vernooy, K. (2014). Evaluation of Left Ventricular Endocardial Cardiac Resynchronization Therapy in a Non-responder with Ventricular Arrhythmias. Indian pacing and electrophysiology journal, 14(1), 32-6. https://doi.org/10.1016/S0972-6292(16)30713-6
- van Dongen, M., van Kraaij, D., Schalla, S., Brunner-La Rocca, H., & Driessen, R. (2014). Severe mitral regurgitation caused by eosinophilic endocarditis. Journal of Cardiology Cases, 10(3). https://doi.org/10.1016/j.jccase.2014.05.012
- van Buchem, M. A., Biessels, G. J., la Rocca, H. P. B., de Craen, A. J. M., van der Flier, W. M., Ikram, M. A., Kappelle, L. J., Koudstaal, P. J., Mooijaart, S. P., Niessen, W., van Oostenbrugge, R., de Roos, A., van Rossum, A. C., & Daemen, M. J. A. P. (2014). The Heart-Brain Connection: A Multidisciplinary Approach Targeting a Missing Link in the Pathophysiology of Vascular Cognitive Impairment. Journal of Alzheimer's Disease, 42, S443-S451. https://doi.org/10.3233/JAD-141542
- 2013
- Arends, S. J., Damoiseaux, J. G., Duijvestijn, A. M., Debrus-Palmans, L., Vroomen, M., Boomars, K. A., Brunner-La Rocca, H. P., Reutelingsperger, C. P., Tervaert, J. W., & van Paassen, P. (2013). Immunoglobulin G anti-endothelial cell antibodies: inducers of endothelial cell apoptosis in pulmonary arterial hypertension?Clinical and Experimental Immunology, 174(3), 433-440. https://doi.org/10.1111/cei.12166
- Kuster, D. W. D., Mulders, J., ten Cate, F. J., Michels, M., dos Remedios, C. G., Martins, P. A. D. C., van der Velden, J., & Oudejans, C. B. M. (2013). MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations. Journal of Molecular and Cellular Cardiology, 65, 59-66. https://doi.org/10.1016/j.yjmcc.2013.09.012
- Dirkx, E., da Costa Martins, P. A., & De Windt, L. J. (2013). Regulation of fetal gene expression in heart failure. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1832(12), 2414-2424. https://doi.org/10.1016/j.bbadis.2013.07.023



