Donners, M. P. C., Wolfs, I. M. J., Olieslagers, S., Mohammadi-Motahhari, Z., Tchaikovski, V., Heeneman, S., van Buul, J. D., Caolo, V., Molin, D. G. M., Post, M. J., & Waltenberger, J. (2010). A Disintegrin and Metalloprotease 10 Is a Novel Mediator of Vascular Endothelial Growth Factor: Induced Endothelial Cell Function in Angiogenesis and Is Associated With Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 30(11), 2188-U382. https://doi.org/10.1161/ATVBAHA.110.213124

van den Berg, S. A., Nabben, M., Bijland, S., Voshol, P. J., van Klinken, J. B., Havekes, L. M., Romijn, H. A., Hoeks, J., Hesselink, M. K., Schrauwen, P., & van Dijk, K. W. (2010). High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57B1/6 mice. Metabolism-Clinical and Experimental, 59(11), 1612-1618. https://doi.org/10.1016/j.metabol.2010.03.008

den Hengst, W. A., Gielis, J. F., Lin, J. Y., Van Schil, P. E. Y., De Windt, L. J., & Moens, A. L. (2010). Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process. American Journal of Physiology-heart and Circulatory Physiology, 299(5), H1283-H1299. https://doi.org/10.1152/ajpheart.00251.2010

Dargaud, Y., Spronk, H. M. H., Leenders, P., Hemker, H. C., & Ten Cate, H. (2010). Monitoring platelet dependent thrombin generation in mice. Thrombosis Research, 126(5), 436-441. https://doi.org/10.1016/j.thromres.2010.08.007

Maeder, M. T., Thompson, B. R., Brunner-La Rocca, H.-P., & Kaye, D. M. (2010). Hemodynamic Basis of Exercise Limitation in Patients With Heart Failure and Normal Ejection Fraction. Journal of the American College of Cardiology, 56(11), 855-863. https://doi.org/10.1016/j.jacc.2010.04.040

Leenders, J. J., Wijnen, W. J., Hiller, M., van der Made, I., Lentink, V., van Leeuwen, R. E. W., Herias, V., Pokharel, S., Heymans, S., de Windt, L. J., Hoydal, M. A., Pinto, Y. M., & Creemers, E. E. (2010). Regulation of Cardiac Gene Expression by KLF15, a Repressor of Myocardin Activity. Journal of Biological Chemistry, 285(35), 27449-27456. https://doi.org/10.1074/jbc.M110.107292

Laeremans, H., Rensen, S. S. M., Ottenheijm, H. C. J., Smits, J. F. M., & Blankesteijn, W. M. (2010). Wnt/frizzled signalling modulates the migration and differentiation of immortalized cardiac fibroblasts. Cardiovascular Research, 87(3), 514-523. https://doi.org/10.1093/cvr/cvq067

Martins, P. A. D. C., Leptidis, S., Salic, K., & De Windt, L. J. (2010). MicroRNA Regulation in Cardiovascular Disease. Current Drug Targets, 11(8), 900-906. https://doi.org/10.2174/138945010791591322

Cosemans, J. M. E. M., Van Kruchten, R., Olieslagers, S., Schurgers, L. J., Verheyen, F. K., Munnix, I. C. A., Waltenberger, J., Angelillo-Scherrer, A., Hoylaerts, M. F., Carmeliet, P., & Heemskerk, J. W. M. (2010). Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization. Journal of Thrombosis and Haemostasis, 8(8), 1797-1808. https://doi.org/10.1111/j.1538-7836.2010.03935.x

Storkebaum, E., de Almodovar, C. R., Meens, M., Zacchigna, S., Mazzone, M., Vanhoutte, G., Vinckier, S., Miskiewicz, K., Poesen, K., Lambrechts, D., Janssen, G. M. J., Fazzi, G. E., Verstreken, P., Haigh, J., Schiffers, P. M., Rohrer, H., Van Der Linden, A., De Mey, J. G. R., & Carmeliet, P. (2010). Impaired Autonomic Regulation of Resistance Arteries in Mice With Low Vascular Endothelial Growth Factor or Upon Vascular Endothelial Growth Factor Trap Delivery. Circulation, 122(3), 273-U107. https://doi.org/10.1161/CIRCULATIONAHA.109.929364

Nawrot, T. S., Staessen, J. A., Holvoet, P., Struijker-Boudier, H. A., Schiffers, P., Van Bortel, L. M., Fagard, R. H., Gardner, J. P., Kimura, M., & Aviv, A. (2010). Telomere length and its associations with oxidized-LDL, carotid artery distensibility and smoking. Frontiers in Bioscience, Elite edition, 2(3), 1164-1168. https://doi.org/10.2741/E176

Kuster, G. M., Nietlispach, F., Kiowski, W., Schindler, R., Bernheim, A. M., Schuetz, P., Mueller, B., Morgenthaler, N. G., Rueter, F., Riesen, W., Rickli, H., & Brunner-La Rocca, H. P. (2010). Role of RAS Inhibition in the Regulation of Cu/Zn-SOD in the Cardiac and Peripheral Arterial Beds in Humans. Clinical Pharmacology & Therapeutics, 87(6), 686-692. https://doi.org/10.1038/clpt.2010.36

Tijsen, A. J., Creemers, E. E., Moerland, P. D., de Windt, L. J., van der Wal, A. C., Kok, W. E., & Pinto, Y. M. (2010). MiR423-5p As a Circulating Biomarker for Heart Failure. Circulation Research, 106(6), 1035-U63. https://doi.org/10.1161/CIRCRESAHA.110.218297

van Oort, R. J., Respress, J. L., Li, N., Reynolds, C., De Almeida, A. C., Skapura, D. G., De Windt, L. J., & Wehrens, X. H. T. (2010). Accelerated Development of Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction in an RyR2-R176Q Knockin Mouse Model. Hypertension, 55(4), 932-938. https://doi.org/10.1161/HYPERTENSIONAHA.109.146449

Muzzarelli, S., Brunner-La Rocca, H., Pfister, O., Foglia, P., Moschovitis, G., Mombelli, G., & Stricker, H. (2010). Adherence to the medical regime in patients with heart failure. European journal of heart failure, 12(4), 389-396. https://doi.org/10.1093/eurjhf/hfq015

Verkaar, F., Blankesteijn, W. M., Smits, J. F. M., & Zaman, G. J. R. (2010). beta-Galactosidase enzyme fragment complementation for the measurement of Wnt/beta-catenin signaling. Faseb Journal, 24(4), 1205-1217. https://doi.org/10.1096/fj.09-141671

McCurdy, S., Baicu, C. F., Heymans, S., & Bradshaw, A. D. (2010). Cardiac extracellular matrix remodeling: Fibrillar collagens and Secreted Protein Acidic and Rich in Cysteine (SPARC). Journal of Molecular and Cellular Cardiology, 48(3), 544-549. https://doi.org/10.1016/j.yjmcc.2009.06.018

Schalla, S., Bekkers, S. C., Dennert, R., van Suylen, R. J., Waltenberger, J., Leiner, T., Wildberger, J., Crijns, H. J., & Heymans, S. (2010). Replacement and reactive myocardial fibrosis in idiopathic dilated cardiomyopathy: comparison of magnetic resonance imaging with right ventricular biopsy. European journal of heart failure, 12(3), 227-231. https://doi.org/10.1093/eurjhf/hfq004

Vanhoutte, D., & Heymans, S. (2010). TIMPs and cardiac remodeling: 'Embracing the MMP-independent-side of the family'. Journal of Molecular and Cellular Cardiology, 48(3), 445-453. https://doi.org/10.1016/j.yjmcc.2009.09.013

Kriemler, S., Zahner, L., Schindler, C., Meyer, U., Hartmann, T., Hebestreit, H., Brunner-La Rocca, H. P., van Mechelen, W., & Puder, J. J. (2010). Effect of school based physical activity programme (KISS) on fitness and adiposity in primary schoolchildren: cluster randomised controlled trial. BMJ, 340, 8. https://doi.org/10.1136/bmj.c785

Schellings, M. W. M., Vanhoutte, D., van Almen, G. C., Swinnen, M., Leenders, J. J. G., Kubben, N., van Leeuwen, R. E. W., Hofstra, L., Heymans, S., & Pinto, Y. M. (2010). Syndecan-1 Amplifies Angiotensin II-Induced Cardiac Fibrosis. Hypertension, 55(2), 249-U87. https://doi.org/10.1161/HYPERTENSIONAHA.109.137885

Dennert, R. M., van Paassen, P., Schalla, S., Kuznetsova, T., Alzand, B. S. N., Staessen, J. A., Velthuis, S., Crijns, H. J., Tervaert, J. W. C., & Heymans, S. (2010). Cardiac Involvement in Churg-Strauss Syndrome. Arthritis & Rheumatism, 62(2), 627-634. https://doi.org/10.1002/art.27263

van Rooij, E., Fielitz, J., Sutherland, L. B., Thijssen, V. L., Crijns, H. J., Dimaio, M. J., Shelton, J., De Windt, L. J., Hill, J. A., & Olson, E. N. (2010). Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Receptor. Circulation Research, 106(1), 155-U315. https://doi.org/10.1161/CIRCRESAHA.109.207084

Lenaers, E., Feyter, H. M., Hoeks, J., Schrauwen, P., Schaart, G., Nabben, M., Nicolay, K., Prompers, J. J., & Hesselink, M. K. (2010). Adaptations in mitochondrial function parallel, but fail to rescue, the transition to severe hyperglycemia and hyperinsulinemia: a study in Zucker diabetic fatty rats.Obesity, 18(6), 1100-1107. https://doi.org/10.1038/oby.2009.372

PROTECT Steering Committee, & Heymans, S. (2010). Design and Rationale of the PROTECT Study: A Placebo-controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function. Journal of Cardiac Failure, 16(1), 25-35. https://doi.org/10.1016/j.cardfail.2009.10.025

el Azzouzi, H., van Oort, R. J., van der Nagel, R., Sluiter, W., Bergmann, M. W., & De Windt, L. J. (2010). MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overload. European journal of heart failure, 12(1), 4-12. https://doi.org/10.1093/eurjhf/hfp165

van den Borne, S. W. M., Diez, J., Blankesteijn, W. M., Verjans, J., Hofstra, L., & Narula, J. (2010). Myocardial remodeling after infarction: the role of myofibroblasts. Nature Reviews Cardiology, 7(1), 30-37. https://doi.org/10.1038/nrcardio.2009.199

Dennert, R., Velthuis, S., Schalla, S., Eurlings, L. W., van Suylen, R.-J., van Paassen, P., Tervaert, J. W. C., Wolffs, P., Goossens, V. J., Bruggeman, C., Waltenberger, J., Crijns, H. J., & Heymans, S. (2010). Intravenous immunoglobulin therapy for patients with idiopathic cardiomyopathy and endomyocardial biopsy-proven high PVB19 viral load. Antiviral Therapy, 15(2), 193-201. https://doi.org/10.3851/IMP1516

Megens, R. T. A., Reitsma, S., Prinzen, L., Egbrink, M. G. A. O., Engels, W., Leenders, P. J. A., Brunenberg, E. J. L., Reesink, K. D., Janssen, B. J. A., Romeny, B. M. T. H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2010). In vivo high-resolution structural imaging of large arteries in small rodents using two-photon laser scanning microscopy. Journal of Biomedical Optics, 15(1), 10. Article 011108. https://doi.org/10.1117/1.3281672

Dennert, R., Velthuis, S., Westermann, D., Donker, D. W., Schalla, S., van Suylen, R.-J., & Heymans, S. (2010). Parvovirus-B19-associated fulminant myocarditis successfully treated with immunosuppressive and antiviral therapy. Antiviral Therapy, 15(4), 681-685. https://doi.org/10.3851/IMP1563

van den Borne, S. W. M., van de Schans, V. A. M., Strzelecka, A. E., Vervoort-Peters, H. T. M., Lijnen, P. M., Cleutjens, J. P. M., Smits, J. F. M., Daemen, M. J. A. P., Janssen, B. J. A., & Blankesteijn, W. M. (2009). Mouse strain determines the outcome of wound healing after myocardial infarction. Cardiovascular Research, 84(2), 273-82. https://doi.org/10.1093/cvr/cvp207

Plat, A. W., Stoffers, H. E. J. H., Klungel, O. H., van Schayck, C. P., de Leeuw, P. W., Soomers, F. L., Schiffers, P. M., Kester, A. D. M., & Kroon, A. A. (2009). The contribution of six polymorphisms to cardiovascular risk in a Dutch high-risk primary care population: the HIPPOCRATES project. Journal of Human Hypertension, 23(10), 659-67. https://doi.org/10.1038/jhh.2009.6

Loubele, S. T. B. G., Spek, C. A., Leenders, P., van Oerle, R., Aberson, H. L., van der Voort, D., Hamulyák, K., Petersen, L. C., Spronk, H. M. H., & ten Cate, H. (2009). Active site inhibited factor VIIa attenuates myocardial ischemia/reperfusion injury in mice. Journal of Thrombosis and Haemostasis, 7(2), 290-8. https://doi.org/10.1111/j.1538-7836.2008.03232.x

Schellings, M. W. M., Vanhoutte, D., Swinnen, M., Cleutjens, J. P., Debets, J., van Leeuwen, R. E. W., d'Hooge, J., Van de Werf, F., Carmeliet, P., Pinto, Y. M., Sage, E. H., & Heymans, S. (2009). Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction. Journal of Experimental Medicine, 206(1), 113-23. https://doi.org/10.1084/jem.20081244

van den Borne, S. W. M., Cleutjens, J. P. M., Hanemaaijer, R., Creemers, E. E., Smits, J. F. M., Daemen, M. J. A. P., & Blankesteijn, W. M. (2008). Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction. Cardiovascular Pathology, 18(1), 37-43. https://doi.org/10.1016/j.carpath.2007.12.012

Hoeks, J., Briede, J. J., de Vogel, J., Schaart, G., Nabben, M., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). Mitochondrial function, content and ROS production in rat skeletal muscle: effect of high-fat feeding. Febs Letters, 582(4), 510-6. https://doi.org/10.1016/j.febslet.2008.01.013

Nabben, M., Hoeks, J., Briede, J. J., Glatz, J. F., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice. Febs Letters, 582(30), 4147-4152. https://doi.org/10.1016/j.febslet.2008.11.016

Megens, R. T. A., Oude Egbrink, M. G. A., Cleutjens, J. P. M., Kuijpers, M. J. E., Schiffers, P. H. M., Merkx, M., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2007). Imaging collagen in intact viable healthy and atherosclerotic arteries using fluorescently labeled CNA35 and two-photon laser scanning microscopy. Molecular Imaging, 6(4), 247-60. https://doi.org/10.2310/7290.2007.00021

Donker, D. W., Maessen, J. G., Verheyen, F., Ramaekers, F., Spätjens, R. L. H., Kuijpers, R., Rarnakers, C., Schiffers, P. M. H., Vos, M. A., Crijns, H. J. G. M., & Volders, P. G. A. (2007). Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium. American Journal of Physiology-heart and Circulatory Physiology, 292(5), H2324-H2332. https://doi.org/10.1152/ajpheart.00392.2006

Goossens, G. H., Jocken, J. W., Blaak, E. E., Schiffers, P. M., Saris, W. H., & van Baak, M. A. (2007). Endocrine Role of the Renin-Angiotensin System in Human Adipose Tissue and Muscle. Effect of {beta}-Adrenergic Stimulation. Hypertension, 49(3), 542-547. https://doi.org/10.1161/01.HYP.0000256091.55393.92

van de Schans, V. A. M., van den Borne, S. W. M., Strzelecka, A. E., Janssen, B. J., van der Velden, J. L., Langen, R. C., Wynshaw Boris, A., Smits, J. F., & Blankesteijn, W. M. (2007). Interruption of Wnt Signaling Attenuates the Onset of Pressure Overload-Induced Cardiac Hypertrophy. Hypertension, 49(3), 473-480. https://doi.org/10.1161/01.HYP.0000255946.55091.24

Megens, R., Reitsma, S., Schiffers, P., Hilgers, R., de Mey, J., Slaaf, D., Oude Egbrink, M., & van Zandvoort, M. (2007). Two-photon microscopy of vital murine elastic and muscular arteries. Combined structural and functional imaging with subcellular resolution. Journal of Vascular Research, 44(2), 87-98. https://doi.org/10.1159/000098259

Jones, E. A. V., le Noble, F., & Eichmann, A. (2006). What determines blood vessel structure? Genetic prespecification vs. hemodynamics. Physiology, 21, 388-95. https://doi.org/10.1152/physiol.00020.2006

van Haaften, R. I. M., Schroen, B. L., Janssen, B. J., van Erk, A. A., Debets, J. J., Smeets, H. J., Smits, J. F., van den Wijngaard, A., Pinto, Y. M., & Evelo, C. T. (2006). Biologically relevant effects of mRNA amplification on gene expression profiles. BMC Bioinformatics, 7, 200. https://doi.org/10.1186/1471-2105-7-200

Goossens, G. H., Blaak, E. E., Schiffers, P. M., Saris, W. H., & van Baak, M. A. (2006). Effect of short-term ACE inhibitor treatment on peripheral insulin sensitivity in obese insulin-resistant subjects. Diabetologia, 49(12), 3009-3016. https://doi.org/10.1007/s00125-006-0458-2

van Empel, V. P. M., Bertrand, A. T., van Oort, R. J., van der Nagel, R., Engelen, M. P. K. J., van Rijen, H. V., Doevendans, P. A. F. M., Crijns, H. J. G. M., Ackerman, S. L., Sluiter, W., & de Windt, L. J. (2006). EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant. Journal of the American College of Cardiology, 48(4), 824-832. https://doi.org/10.1016/j.jacc.2006.02.075

Sharma, U. C., Pokharel, S., van Brakel, T. J., van Berlo, J. H., Cleutjens, J. P. M., Schroen, B., André, S., Crijns, H. J. G. M., Gabius, H.-J., Maessen, J., & Pinto, Y. M. (2004). Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation, 110(19), 3121-8. https://doi.org/10.1161/01.CIR.0000147181.65298.4D

Schroen, B., Heymans, S., Sharma, U., Blankesteijn, W. M., Pokharel, S., Cleutjens, J. P. M., Porter, J. G., Evelo, C. T. A., Duisters, R., van Leeuwen, R. E. W., Janssen, B. J. A., Debets, J. J. M., Smits, J. F. M., Daemen, M. J. A. P., Crijns, H. J. G. M., Bornstein, P., & Pinto, Y. M. (2004). Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy. Circulation Research, 95(5), 515-522. https://doi.org/10.1161/01.RES.0000141019.20332.3e

De Celle, T., Cleutjens, J. P., Blankesteijn, W. M., Debets, J. J., Smits, J. F., & Janssen, B. J. (2004). Long-term structural and functional consequences of cardiac ischaemia-reperfusion injury in vivo in mice. Experimental Physiology, 89(5), 605-15. https://doi.org/10.1113/expphysiol.2004.027649