Bartholomé, R., Haenen, G. R. M. M., Hollman, C. H., Bast, A., Dagnelie, P. C., Roos, D., Keijer, J., Kroon, P. A., Needs, P. W., & Arts, C. W. (2010). Deconjugation Kinetics of Glucuronidated Phase II Flavonoid Metabolites by beta-glucuronidase from Neutrophils. Drug metabolism and pharmacokinetics, 25(4), 379-87. https://doi.org/10.2133/dmpk.DMPK-10-RG-002

den Hartog, G. J., Boots, A. W., Adam Perrot, A., Brouns, F. J. P. H., Verkooijen, I. W., Weseler, A. R., Haenen, G. R., & Bast, A. (2010). Erythritol is a sweet antioxidant. Nutrition, 26(4), 449-458. https://doi.org/10.1016/j.nut.2009.05.004

Gungor, N., Knaapen, A. M., Munnia, A., Peluso, M., Haenen, G. R., Chiu, R. K., Godschalk, R. W., & van Schooten, F. J. (2010). Genotoxic effects of neutrophils and hypochlorous acid. Mutagenesis, 25(2), 149-154. https://doi.org/10.1093/mutage/gep053

Bast, A., Weseler, A. R., Haenen, G. R. M. M., & den Hartog, G. J. M. (2010). Oxidative stress and antioxidants in interstitial lung disease.Current Opinion in Pulmonary Medicine, 16(5), 516-520. https://doi.org/10.1097/MCP.0b013e32833c645d

Wijnen, P. A., Linssen, C. F., Haenen, G. R., Bekers, O., & Drent, M. (2010). Variant VKORC1 and CYP2C9 Alleles in Patients with Diffuse Alveolar Hemorrhage Caused by Oral Anticoagulants. Molecular Diagnosis & Therapy, 14(1), 23-30. https://doi.org/10.1007/BF03256350

Anson, N. M., Havenaar, R., Bast, A., & Haenen, G. R. M. M. (2010). Antioxidant and anti-inflammatory capacity of bioaccessible compounds from wheat fractions after gastrointestinal digestion. Journal of Cereal Science, 51(1), 110-114. https://doi.org/10.1016/j.jcs.2009.10.005

PROTECT Steering Committee, & Heymans, S. (2010). Design and Rationale of the PROTECT Study: A Placebo-controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function. Journal of Cardiac Failure, 16(1), 25-35. https://doi.org/10.1016/j.cardfail.2009.10.025

el Azzouzi, H., van Oort, R. J., van der Nagel, R., Sluiter, W., Bergmann, M. W., & De Windt, L. J. (2010). MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overload. European journal of heart failure, 12(1), 4-12. https://doi.org/10.1093/eurjhf/hfp165

van den Borne, S. W. M., Diez, J., Blankesteijn, W. M., Verjans, J., Hofstra, L., & Narula, J. (2010). Myocardial remodeling after infarction: the role of myofibroblasts. Nature Reviews Cardiology, 7(1), 30-37. https://doi.org/10.1038/nrcardio.2009.199

Dennert, R., Velthuis, S., Schalla, S., Eurlings, L. W., van Suylen, R.-J., van Paassen, P., Tervaert, J. W. C., Wolffs, P., Goossens, V. J., Bruggeman, C., Waltenberger, J., Crijns, H. J., & Heymans, S. (2010). Intravenous immunoglobulin therapy for patients with idiopathic cardiomyopathy and endomyocardial biopsy-proven high PVB19 viral load. Antiviral Therapy, 15(2), 193-201. https://doi.org/10.3851/IMP1516

Megens, R. T. A., Reitsma, S., Prinzen, L., Egbrink, M. G. A. O., Engels, W., Leenders, P. J. A., Brunenberg, E. J. L., Reesink, K. D., Janssen, B. J. A., Romeny, B. M. T. H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2010). In vivo high-resolution structural imaging of large arteries in small rodents using two-photon laser scanning microscopy. Journal of Biomedical Optics, 15(1), 10. Article 011108. https://doi.org/10.1117/1.3281672

Dennert, R., Velthuis, S., Westermann, D., Donker, D. W., Schalla, S., van Suylen, R.-J., & Heymans, S. (2010). Parvovirus-B19-associated fulminant myocarditis successfully treated with immunosuppressive and antiviral therapy. Antiviral Therapy, 15(4), 681-685. https://doi.org/10.3851/IMP1563

van den Borne, S. W. M., van de Schans, V. A. M., Strzelecka, A. E., Vervoort-Peters, H. T. M., Lijnen, P. M., Cleutjens, J. P. M., Smits, J. F. M., Daemen, M. J. A. P., Janssen, B. J. A., & Blankesteijn, W. M. (2009). Mouse strain determines the outcome of wound healing after myocardial infarction. Cardiovascular Research, 84(2), 273-82. https://doi.org/10.1093/cvr/cvp207

Plat, A. W., Stoffers, H. E. J. H., Klungel, O. H., van Schayck, C. P., de Leeuw, P. W., Soomers, F. L., Schiffers, P. M., Kester, A. D. M., & Kroon, A. A. (2009). The contribution of six polymorphisms to cardiovascular risk in a Dutch high-risk primary care population: the HIPPOCRATES project. Journal of Human Hypertension, 23(10), 659-67. https://doi.org/10.1038/jhh.2009.6

de Jongh, R., Dambros, M., Haenen, G. R., den Hartog, G. J., Bast, A., van Kerrebroeck, P. E., & van Koeveringe, G. A. (2009). Partial bladder outlet obstruction reduces the tissue antioxidant capacity and muscle nerve density of the guinea pig bladder. Neurourology and Urodynamics, 28(5), 461-467. https://doi.org/10.1002/nau.20677

Loubele, S. T. B. G., Spek, C. A., Leenders, P., van Oerle, R., Aberson, H. L., van der Voort, D., Hamulyák, K., Petersen, L. C., Spronk, H. M. H., & ten Cate, H. (2009). Active site inhibited factor VIIa attenuates myocardial ischemia/reperfusion injury in mice. Journal of Thrombosis and Haemostasis, 7(2), 290-8. https://doi.org/10.1111/j.1538-7836.2008.03232.x

Schellings, M. W. M., Vanhoutte, D., Swinnen, M., Cleutjens, J. P., Debets, J., van Leeuwen, R. E. W., d'Hooge, J., Van de Werf, F., Carmeliet, P., Pinto, Y. M., Sage, E. H., & Heymans, S. (2009). Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction. Journal of Experimental Medicine, 206(1), 113-23. https://doi.org/10.1084/jem.20081244

Boots, A. W., Drent, M., Swennen, E. L., Moonen, H. J., Bast, A., & Haenen, G. R. (2009). Antioxidant status associated with inflammation in sarcoidosis: A potential role for antioxidants. Respiratory Medicine, 103(3), 364-372. https://doi.org/10.1016/j.rmed.2008.10.007

Boots, A. W., Hristova-Dijkstra, M. J., Kasahara, D. I., Haenen, G. R., Bast, A., & van der Vliet, A. (2009). ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli.Journal of Biological Chemistry, 284(26), 17858-17867. https://doi.org/10.1074/jbc.M809761200

Mateo Anson, N., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. (2009). Bioavailability of ferulic acid is determined by its bioaccessibility. Journal of Cereal Science, 49(2), 296-300. https://doi.org/10.1016/j.jcs.2008.12.001

Mateo Anson, N., Selinheimo, E., Havenaar, R., Aura, A. M., Mattila, I., Lehtinen, P., Bast, A., Poutanen, K., & Haenen, G. R. (2009). Bioprocessing of wheat bran improves in vitro bioaccessibility and colonic metabolism of phenolic compounds.Journal of Agricultural and Food Chemistry, 57(14), 6148-6155. https://doi.org/10.1021/jf900492h

Jacobs, H., van der Vijgh, W. J., Koek, G. H., Draaisma, G. J., Moalin, M., van Strijdonck, G. P., Bast, A., & Haenen, G. R. (2009). Characterization of the glutathione conjugate of the semisynthetic flavonoid monoHER. Free Radical Biology and Medicine, 46(12), 1567-1573. https://doi.org/10.1016/j.freeradbiomed.2009.02.031

Balk, J. M., Bast, A., & Haenen, G. R. (2009). Evaluation of the accuracy of antioxidant competition assays: incorrect assumptions with major impact.Free Radical Biology and Medicine, 47(2), 135-144. https://doi.org/10.1016/j.freeradbiomed.2009.04.009

Donners, M. M. P. C., Beckers, L., Lievens, D., Munnix, I., Heemskerk, J., Janssen, B. J., Wijnands, E., Cleutjens, J., Zernecke, A., Weber, C., Ahonen, C. L., Benbow, U., Newby, A. C., Noelle, R. J., Daemen, M. J. A. P., & Lutgens, E. (2008). The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling. Blood, 111(9), 4596-604. https://doi.org/10.1182/blood-2007-05-088906

van den Borne, S. W. M., Cleutjens, J. P. M., Hanemaaijer, R., Creemers, E. E., Smits, J. F. M., Daemen, M. J. A. P., & Blankesteijn, W. M. (2008). Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction. Cardiovascular Pathology, 18(1), 37-43. https://doi.org/10.1016/j.carpath.2007.12.012

Smeets, P. J. H., Teunissen, B. E. J., Willemsen, P. H. M., van Nieuwenhoven, F. A., Brouns, A. E., Janssen, B. J. A., Cleutjens, J. P. M., Staels, B., van der Vusse, G. J., & van Bilsen, M. (2008). Cardiac hypertrophy is enhanced in PPAR alpha-/- mice in response to chronic pressure overload. Cardiovascular Research, 78(1), 79-89. https://doi.org/10.1093/cvr/cvn001

Mateo Anson, N., van den Berg, R., Havenaar, R., Haenen, G. R., & Bast, A. (2008). Antioxidant and anti-inflammatory potency of different wheat varieties and fractions. Proceedings of the Nutrition Society, 67(OCE1), Article E56. https://doi.org/10.1017/S0029665108006654

Mateo Anson, N., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. R. M. (2008). Ferulic Acid from Aleurone Determines the Antioxidant Potency of Wheat Grain (Triticum aestivum L.). Journal of Agricultural and Food Chemistry, 56(14), 5589-5594. https://doi.org/10.1021/jf800445k

Boots, A. W., Haenen, G. R., & Bast, A. (2008). Health effects of quercetin: from antioxidant to nutraceutical.European Journal of Pharmacology, 585(2-3), 325-337. https://doi.org/10.1016/j.ejphar.2008.03.008

Boots, A., Wilms, L. C., Swennen, E. L., Kleinjans, J. C., Bast, A., & Haenen, G. R. (2008). In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers. Nutrition, 24(7-8), 703-10. https://doi.org/10.1016/j.nut.2008.03.023

de Jongh, R., Haenen, G. R. M. M., van Koeveringe, G. A., Dambros, M., & van Kerrebroeck, P. E. V. (2008). Lipid peroxidation product 4-hydroxynonenal contributes to bladder smooth muscle damage.Urology, 71(5), 974-978. https://doi.org/10.1016/j.urology.2007.11.014

Hoeks, J., Briede, J. J., de Vogel, J., Schaart, G., Nabben, M., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). Mitochondrial function, content and ROS production in rat skeletal muscle: effect of high-fat feeding. Febs Letters, 582(4), 510-6. https://doi.org/10.1016/j.febslet.2008.01.013

Wijnen, P. A. H. M., Drent, M., Nelemans, P. J., Kuijpers, P. M., Koek, G. H., Neef, C. K., Haenen, G. R., & Bekers, O. (2008). Role of cytochrome p450 polymorphisms in the development of pulmonary drug toxicity: a case-control study in the Netherlands. Drug Safety, 31(12), 1125-34. https://doi.org/10.2165/0002018-200831120-00008

Rensen, S., Niessen, P. M., van Deursen, J. M., Janssen, B. J., Heijman, E., Hermeling, E., Meens, M. J. P. M. T., Lie, N., Gijbels, M. J., Strijkers, G. J., Doevendans, P. A., Hofker, M. H., de Mey, J. G., & van Eys, G. J. (2008). Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice. Circulation, 118(8), 828-36. https://doi.org/10.1161/CIRCULATIONAHA.107.743690

Nabben, M., Hoeks, J., Briede, J. J., Glatz, J. F., Kornips, E., Hesselink, M. K., & Schrauwen, P. (2008). The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice. Febs Letters, 582(30), 4147-4152. https://doi.org/10.1016/j.febslet.2008.11.016

Megens, R. T. A., Oude Egbrink, M. G. A., Cleutjens, J. P. M., Kuijpers, M. J. E., Schiffers, P. H. M., Merkx, M., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2007). Imaging collagen in intact viable healthy and atherosclerotic arteries using fluorescently labeled CNA35 and two-photon laser scanning microscopy. Molecular Imaging, 6(4), 247-60. https://doi.org/10.2310/7290.2007.00021

Donker, D. W., Maessen, J. G., Verheyen, F., Ramaekers, F., Spätjens, R. L. H., Kuijpers, R., Rarnakers, C., Schiffers, P. M. H., Vos, M. A., Crijns, H. J. G. M., & Volders, P. G. A. (2007). Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium. American Journal of Physiology-heart and Circulatory Physiology, 292(5), H2324-H2332. https://doi.org/10.1152/ajpheart.00392.2006

Rezk, B. M., van der Vijgh, W. J., Bast, A., & Haenen, G. R. (2007). Alpha-tocopheryl phosphate is a novel apoptotic agent. Frontiers in Bioscience, 12, 2013-2019. https://doi.org/10.2741/2206

Haenen, G. R. M. M., & Bast, A. (2007). Antioxidanten overbodig? Prietpraat!Chemisch2Weekblad, 102(18), 26-27.

Rietjens, S. J., Beelen, M., Koopman, R., van Loon, L. J., Bast, A., & Haenen, G. R. (2007). A single session of resistance exercise induces oxidative damage in untrained men. Medicine and Science in Sports and Exercise, 39(12), 2145-2151. https://doi.org/10.1249/mss.0b013e318157936d

Coleman, M. D., Rimmer, G. S., & Haenen, G. R. (2007). Effects of Lipoic Acid and Dihydrolipoic Acid on Total Erythrocytic Thiols under Conditions of Restricted Glucose in vitro. Basic & Clinical Pharmacology & Toxicology, 100(2), 139-144. https://doi.org/10.1111/j.1742-7843.2006.00025.x

Goossens, G. H., Jocken, J. W., Blaak, E. E., Schiffers, P. M., Saris, W. H., & van Baak, M. A. (2007). Endocrine Role of the Renin-Angiotensin System in Human Adipose Tissue and Muscle. Effect of {beta}-Adrenergic Stimulation. Hypertension, 49(3), 542-547. https://doi.org/10.1161/01.HYP.0000256091.55393.92

Wilms, L. C., Boots, A. W., de Boer, V. C., Maas, L. M., Pachen, D. M., Gottschalk, R. W., Ketelslegers, H., Godschalk, R. W., Haenen, G. R., van Schooten, F. J., & Kleinjans, J. C. (2007). Impact of multiple genetic polymorphisms on effects of a 4-week blueberry juice intervention on ex vivo induced lymphocytic DNA damage in human volunteers. Carcinogenesis, 28(8), 1800-1806. https://doi.org/10.1093/carcin/bgm145

van de Schans, V. A. M., van den Borne, S. W. M., Strzelecka, A. E., Janssen, B. J., van der Velden, J. L., Langen, R. C., Wynshaw Boris, A., Smits, J. F., & Blankesteijn, W. M. (2007). Interruption of Wnt Signaling Attenuates the Onset of Pressure Overload-Induced Cardiac Hypertrophy. Hypertension, 49(3), 473-480. https://doi.org/10.1161/01.HYP.0000255946.55091.24

Rietjens, S. J., Bast, A., & Haenen, G. R. (2007). New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol. Journal of Agricultural and Food Chemistry, 55(18), 7609-7614. https://doi.org/10.1021/jf0706934

Arts, M. J., Grun, C., Jong, R. L., Voss, H. P., Bast, A., Mueller, M. J., & Haenen, G. R. (2007). Oxidative Degradation of Lipids during Mashing. Journal of Agricultural and Food Chemistry, 55(17), 7010-7014. https://doi.org/10.1021/jf070505+

de Jongh, R., Haenen, G. R., van Koeveringe, G. A., Dambros, M., de Mey, J. G., & van Kerrebroeck, P. E. V. A. (2007). Oxidative stress reduces the muscarinic receptor function in the urinary bladder. Neurourology and Urodynamics, 26(2), 302-308. https://doi.org/10.1002/nau.20298

Bast, A., Haenen, G. R., Bruynzeel, A. M., & van der Vijgh, W. J. (2007). Protection by flavonoids against anthracycline cardiotoxicity: from chemistry to clinical trials. Cardiovascular Toxicology, 7(2), 154-159. https://doi.org/10.1007/s12012-007-0018-0

Bast, A., Kaiserova, H., den Hartog, G. J., Haenen, G. R., & van der Vijgh, W. J. (2007). Protectors against doxorubicin-induced cardiotoxicity: Flavonoids. Cell Biology and Toxicology, 23(1), 39-47. https://doi.org/10.1007/s10565-006-0139-4

Rietjens, S. J., Bast, A., Vente, J. D., & Haenen, G. (2007). The olive oil antioxidant hydroxytyrosol efficiently protects against the oxidative stress induced impairment of the NO{middle dot} response of isolated rat aorta. American Journal of Physiology-heart and Circulatory Physiology, 292(4), H1931-H1936. https://doi.org/10.1152/ajpheart.00755.2006