• 2022
    • Wu, L., Baylan, U., van der Leeden, B., Schurink, B., Roos, E., Schalkwijk, C. G., Bugiani, M., van der Valk, P., van Rossum, A. C., Zeerleder, S. S., Heunks, L. M. A., Boon, R. A., de Boer, O. J., van der Wal, A. C., Niessen, H. W. M., & Krijnen, P. A. J. (2022). Cardiac inflammation and microvascular procoagulant changes are decreased in second wave compared to first wave deceased COVID-19 patients. International Journal of Cardiology, 349, 157-165. https://doi.org/10.1016/j.ijcard.2021.11.079
    • Linkens, A. M. A., Houben, A. J. H. M., Kroon, A. A., Schram, M. T., Berendschot, T. T. J. M., Webers, C. A. B., van Greevenbroek, M., Henry, R. M. A., de Galan, B., Stehouwer, C. D. A., Eussen, S. J. M. P., & Schalkwijk, C. G. (2022). Habitual intake of dietary advanced glycation end products is not associated with generalized microvascular function-the Maastricht Study. American Journal of Clinical Nutrition, 115(2), 444-455. https://doi.org/10.1093/ajcn/nqab302
    • Weerts, J., Mourmans, S. G. J., Barandiaran Aizpurua, A., Schroen, B. L. M., Knackstedt, C., Eringa, E., Houben, A. J. H. M., & van Empel, V. P. M. (2022). The Role of Systemic Microvascular Dysfunction in Heart Failure with Preserved Ejection Fraction. Biomolecules, 12(2), [278]. https://doi.org/10.3390/biom12020278
    • van Dinther, M., Schram, M. T., Jansen, J. F. A., Backes, W. H., Houben, A. J. H. M., Berendschot, T. T. J. M., Schalkwijk, C. G., Stehouwer, C. D. A., van Oostenbrugge, R. J., & Staals, J. (2022). Extracerebral microvascular dysfunction is related to brain MRI markers of cerebral small vessel disease: The Maastricht Study. Geroscience, 44(1), 147-157. https://doi.org/10.1007/s11357-021-00493-0
    • Beran, M., Muzambi, R., Geraets, A., Albertorio-Diaz, J. R., Adriaanse, M. C., Iversen, M. M., Kokoszka, A., Nefs, G., Nouwen, A., Pouwer, F., Huber, J. W., Schmitt, A., Schram, M. T., & European Depression in Diabetes (EDID) Research Consortium (2022). The bidirectional longitudinal association between depressive symptoms and HbA(1c): A systematic review and meta-analysis. Diabetic Medicine, 39(2), [e14671]. https://doi.org/10.1111/dme.14671
    • Jonkman, T. H., Dekkers, K. F., Slieker, R. C., Grant, C. D., Ikram, M. A., van Greevenbroek, M. M. J., Franke, L., Veldink, J. H., Boomsma, D. I., Slagboom, P. E., Consortium, B. I. O. S., & Heijmans, B. T. (2022). Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression. Genome Biology, 23(1), [24]. https://doi.org/10.1186/s13059-021-02585-8
    • Maasen, K., Eussen, S. J. P. M., Scheijen, J. L. J. M., van der Kallen, C. J. H., Dagnelie, P. C., Opperhuizen, A., Stehouwer, C. D. A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2022). Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: the Maastricht Study. American Journal of Clinical Nutrition, 115(1), 34-44. https://doi.org/10.1093/ajcn/nqab329
    • Obeid, R., Eussen, S. J. P. M., Mommers, M., Smits, L., & Thijs, C. (2022). Imbalanced Folate and Vitamin B12 in the Third Trimester of Pregnancy and its Association with Birthweight and Child Growth up to 2 Years. Molecular Nutrition & Food Research, 66(2), [2100662]. https://doi.org/10.1002/mnfr.202100662
    • Hoogeveen, R. M., Hanssen, N. M. J., Brouwer, J. R., Mosterd, A., Tack, C. J., Kroon, A. A., De Borst, G. J., Ten Berg, J., Van Trier, T., Van Lennep, J. R., Liem, A., Serne, E., Visseren, F. L. J., Cornel, J. H., Peters, R. J. G., Jukema, J. W., Stroes, E. S. G., & PANORAMA working group (2022). The challenge of choosing in cardiovascular risk management. Netherlands Heart Journal, 30(1), 47-57. https://doi.org/10.1007/s12471-021-01599-y
  • 2021
    • Qiao, Y-S., Chai, Y-H., Gong, H-J., Zhuldyz, Z., Stehouwer, C. D. A., Zhou, J-B., & Simó, R. (2021). The Association Between Diabetes Mellitus and Risk of Sarcopenia: Accumulated Evidences From Observational Studies. Frontiers in Endocrinology, 12, [782391]. https://doi.org/10.3389/fendo.2021.782391
    • Malik, A. E. F., Delhaas, T., Spronck, B., Henry, R. M. A., Joseph, J., Stehouwer, C. D. A., Mess, W. H., & Reesink, K. D. (2021). Single M-Line Is as Reliable as Multiple M-Line Ultrasound for Carotid Artery Screening. Frontiers in physiology, 12, [787083]. https://doi.org/10.3389/fphys.2021.787083
    • van Son, J., Oussaada, S. M., Sekercan, A., Beudel, M., Dongelmans, D. A., van Assen, S., Eland, I. A., Moeniralam, H. S., Dormans, T. P. J., van Kalkeren, C. A. J., Douma, R. A., Rusch, D., Simsek, S., Liu, L., Kootte, R. S., Wyers, C. E., IJzerman, R. G., van den Bergh, J. P., Stehouwer, C. D. A., ... Serlie, M. J. (2021). Overweight and Obesity Are Associated With Acute Kidney Injury and Acute Respiratory Distress Syndrome, but Not With Increased Mortality in Hospitalized COVID-19 Patients: A Retrospective Cohort Study. Frontiers in Endocrinology, 12, [747732]. https://doi.org/10.3389/fendo.2021.747732
    • Mao, Z., Aglago, E. K., Zhao, Z., Schalkwijk, C., Jiao, L., Freisling, H., Weiderpass, E., Hughes, D. J., Eriksen, A. K., Tjønneland, A., Severi, G., Rothwell, J., Boutron-Ruault, M-C., Katzke, V., Kaaks, R., Schulze, M. B., Birukov, A., Krogh, V., Panico, S., ... Fedirko, V. (2021). Dietary Intake of Advanced Glycation End Products (AGEs) and Mortality among Individuals with Colorectal Cancer. Nutrients, 13(12), [4435]. https://doi.org/10.3390/nu13124435
    • Kalafati, M., Kutmon, M., Evelo, C. T., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., Blaak, E. E., van Greevenbroek, M. M. J., Adriaens, M., & BIOS Consortium (2021). An interferon-related signature characterizes the whole blood transcriptome profile of insulin-resistant individuals-the CODAM study. Genes and nutrition, 16(1), [22]. https://doi.org/10.1186/s12263-021-00702-7
    • Barutta, F., Corbetta, B., Bellini, S., Guarrera, S., Matullo, G., Scandella, M., Schalkwijk, C., Stehouwer, C. D., Chaturvedi, N., Soedamah-Muthu, S. S., Durazzo, M., & Gruden, G. (2021). MicroRNA 146a is associated with diabetic complications in type 1 diabetic patients from the EURODIAB PCS. Journal of Translational Medicine, 19(1), [475]. https://doi.org/10.1186/s12967-021-03142-4
    • Gijs, M., Ramakers, I. H. G. B., Visser, P. J., Verhey, F. R. J., van de Waarenburg, M. P. H., Schalkwijk, C. G., Nuijts, R. M. M. A., & Webers, C. A. B. (2021). Association of tear fluid amyloid and tau levels with disease severity and neurodegeneration. Scientific Reports, 11(1), [22675]. https://doi.org/10.1038/s41598-021-01993-x
    • van der Heide, F. C. T., Steens, I. L. M., Geraets, A. F. J., Foreman, Y. D., Henry, R. M. A., Kroon, A. A., van der Kallen, C. J. H., van Sloten, T. T., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., van Greevenbroek, M. M. J., Wesselius, A., Koster, A., Schaper, N. C., Schram, M. T., ... Stehouwer, C. D. A. (2021). Association of Retinal Nerve Fiber Layer Thickness, an Index of Neurodegeneration, With Depressive Symptoms Over Time. Jama network open, 4(11), e2134753. [2134753]. https://doi.org/10.1001/jamanetworkopen.2021.34753
    • Tinnevelt, G. H., Wouters, K., Postma, G. J., Folcarelli, R., & Jansen, J. J. (2021). High-throughput single cell data analysis - A tutorial. Analytica Chimica Acta, 1185, [338872]. https://doi.org/10.1016/j.aca.2021.338872
    • Bogie, J. F. J., Vanmierlo, T., Vanmol, J., Timmermans, S., Mailleux, J., Nelissen, K., Wijnands, E., Wouters, K., Stinissen, P., Gustafsson, J. A., Steffensen, K. R., Mulder, M., Zelcer, N., & Hendriks, J. J. A. (2021). Liver X receptor beta deficiency attenuates autoimmune-associated neuroinflammation in a T cell-dependent manner. Journal of Autoimmunity, 124, [102723]. https://doi.org/10.1016/j.jaut.2021.102723
    • Korn, A., Baylan, U., Simsek, S., Schalkwijk, C. G., Niessen, H. W. M., & Krijnen, P. A. J. (2021). Myocardial infarction coincides with increased NOX2 and Nε-(carboxymethyl) lysine expression in the cerebral microvasculature. Open Heart, 8(2), [e001842]. https://doi.org/10.1136/openhrt-2021-001842
    • Tang, X. Y., Zhao, W., Lu, M., Zhang, X., Zhang, P., Xin, Z., Sun, R., Tian, W., Cardoso, M. A., Yang, J. K., Sim, R., Zhou, J. B., & Stehouwer, C. D. A. (2021). Relationship between Central Obesity and the incidence of Cognitive Impairment and Dementia from Cohort Studies Involving 5,060,687 Participants. Neuroscience and Biobehavioral Reviews, 130, 301-313. https://doi.org/10.1016/j.neubiorev.2021.08.028
    • Strikwerda, M., Beulens, J. W., Remmelzwaal, S., Schoonmade, L. J., van Straten, A., Schram, M. T., Elders, P. J., & Rutters, F. (2021). The Association of Burnout and Vital Exhaustion With Type 2 Diabetes: A Systematic Review and Meta-Analysis. Psychosomatic Medicine, 83(9), 1013-1030. https://doi.org/10.1097/PSY.0000000000000995
    • van Gennip, A. C. E., Stehouwer, C. D. A., van Boxtel, M. P. J., Verhey, F. R. J., Koster, A., Kroon, A. A., Köhler, S., van Greevenbroek, M. M. J., Wesselius, A., Eussen, S. J. P. M., Backes, W. H., Jansen, J. F., Schram, M. T., Henry, R. M. A., Singh-Manoux, A., & van Sloten, T. T. (2021). Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia. Diabetes Care, 44(11), 2493-2502. https://doi.org/10.2337/dc21-0149
    • Bakker, L., Ramakers, I. H. G. B., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., van der Kallen, C. J. H., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Midttun, Ø., Ueland, P. M., Verhey, F. R. J., Eussen, S. J. P. M., & Köhler, S. (2021). Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study. Diabetologia, 64(11), 2445-2457. https://doi.org/10.1007/s00125-021-05521-4
    • Wu, W., Bours, M., Koole, A., Kenkhuis, M. F., Eussen, S., Breukink, S., van Schooten, F., Weijenberg, M., & Hageman, G. (2021). Cross-Sectional Associations between Dietary Daily Nicotinamide Intake and Patient-Reported Outcomes in Colorectal Cancer Survivors, 2 to 10 Years Post-Diagnosis. Nutrients, 13(11), [3707]. https://doi.org/10.3390/nu13113707
    • van der Bruggen, M. M., Spronck, B., Delhaas, T., Reesink, K. D., & Schalkwijk, C. G. (2021). The Putative Role of Methylglyoxal in Arterial Stiffening: A Review. Heart Lung and Circulation, 30(11), 1681-1693. https://doi.org/10.1016/j.hlc.2021.06.527
    • van Dalem, J., Driessen, J. H. M., Burden, A. M., Stehouwer, C. D. A., Klungel, O. H., de Vries, F., & Brouwers, M. C. G. J. (2021). Thiazolidinediones and Glucagon-Like Peptide-1 Receptor Agonists and the Risk of Nonalcoholic Fatty Liver Disease: A Cohort Study. Hepatology, 74(5), 2467-2477. https://doi.org/10.1002/hep.32012
    • Willems, R. A. L., Spaetgens, B., Conemans, L. H., Wesseling, G., Stehouwer, C. D. A., & Alnima, T. (2021). High flow nasal cannula in older vulnerable COVID-19 patients: A missed opportunity?Respiratory Medicine, 189, [106666]. https://doi.org/10.1016/j.rmed.2021.106666
    • Kremers, S. H. M., Remmelzwaal, S., Schalkwijk, C. G., Elders, P. J. M., Stehouwer, C. D. A., van Ballegooijen, A. J., & Beulens, J. W. J. (2021). The role of serum and dietary advanced glycation endproducts in relation to cardiac function and structure: The Hoorn Study. Nutrition Metabolism and Cardiovascular Diseases, 31(11), 3167-3175. https://doi.org/10.1016/j.numecd.2021.07.020
    • Remmelzwaal, S., Beulens, J. W. J., Elders, P. J. M., Stehouwer, C. D. A., Handoko, M. L., Appelman, Y., van Empel, V., Heymans, S. R. B., & van Ballegooijen, A. J. (2021). Sex-specific associations of body composition measures with cardiac function and structure after 8 years of follow-up. Scientific Reports, 11(1), [21046]. https://doi.org/10.1038/s41598-021-00541-x
    • Beulens, J. W. J., Dal Canto, E., Stehouwer, C. D. A., Rennenberg, R. J. M. W., Elders, P. J. M., & van Ballegooijen, A. J. (2021). High vitamin K status is prospectively associated with decreased left ventricular mass in women: the Hoorn Study. Nutrition Journal, 20(1), [85]. https://doi.org/10.1186/s12937-021-00742-0
    • Pinxt, C. M. H., Bogie, R. M. M., Hanssen, N. M. J., & Spaetgens, B. (2021). Antibiotic overuse in older patients: an important clinical reminder of pseudomembranous colitis. QJM: An International Journal of Medicine, 114(10), 755-756. https://doi.org/10.1093/qjmed/hcab198
    • Gianfredi, V., Beran, M., Koster, A., Eussen, S. J. P. M., Odone, A., Signorelli, C., Schaper, N. C., Köhler, S., Bosma, H., Dagnelie, P. C., Stehouwer, C. D. A., Wesselius, A., Amerio, A., Brinkhues, S., Dukers-Muijrers, N., & Schram, M. T. (2021). Association between social network characteristics and prevalent and incident depression: The Maastricht Study. Journal of Affective Disorders, 293, 338-346. https://doi.org/10.1016/j.jad.2021.06.046
    • Gijs, M., Veugen, J. M. J., Wolffs, P. F. G., Savelkoul, P. H. M., Tas, J., van Bussel, B. C. T., de Kruif, M. D., Henry, R. M. A., Webers, C. A. B., Dickman, M. M., & Nuijts, R. M. M. A. (2021). In-Depth Investigation of Conjunctival Swabs and Tear Fluid of Symptomatic COVID-19 Patients, an Observational Cohort Study. Translational Vision Science & Technology, 10(12), [32]. https://doi.org/10.1167/tvst.10.12.32
    • Janssen, E. P. C. J., Köhler, S., Geraets, A. F. J., Stehouwer, C. D. A., Schaper, N. C., Sep, S. J. S., Henry, R. M. A., van der Kallen, C. J. H., Schalkwijk, C. G., Koster, A., Verhey, F. R., & Schram, M. T. (2021). Low-grade inflammation and endothelial dysfunction predict four-year risk and course of depressive symptoms: The Maastricht study. Brain Behavior and Immunity, 97, 61-67. https://doi.org/10.1016/j.bbi.2021.06.013
    • Molto-Puigmarti, C., Obeid, R., Mommers, M., Eussen, S. J. P. M., & Thijs, C. (2021). Maternal plasma choline and betaine in late pregnancy and child growth up to age 8 years in the KOALA Birth Cohort Study. American Journal of Clinical Nutrition, 114(4), 1438-1446. https://doi.org/10.1093/ajcn/nqab177
    • Heger, I. S., Deckers, K., Schram, M. T., Stehouwer, C. DA., Dagnelie, P. C., van der Kallen, C. J., Koster, A., Eussen, S. J., Jansen, J. F., Verhey, F. R., van Boxtel, M. P., & Köhler, S. (2021). Associations of the Lifestyle for Brain Health Index With Structural Brain Changes and Cognition: Results From the Maastricht Study. Neurology, 97(13), E1300-E1312. https://doi.org/10.1212/WNL.0000000000012572
    • Veldhuizen, G. P., Alnazer, R. M., de Leeuw, P. W., & Kroon, A. A. (2021). The Effects of Verapamil, Hydralazine, and Doxazosin on Renin, Aldosterone, and the Ratio Thereof. Cardiovascular Drugs and Therapy. https://doi.org/10.1007/s10557-021-07262-3
    • Aglago, E. K., Mayen, A. L., Knaze, V., Freisling, H., Fedirko, V., Hughes, D. J., Jiao, L., Eriksen, A. K., Tjonneland, A., Boutron-Ruault, M. C., Rothwell, J. A., Severi, G., Kaaks, R., Katzke, V., Schulze, M. B., Birukov, A., Palli, D., Sieri, S., de Magistris, M. S., ... Jenab, M. (2021). Dietary Advanced Glycation End-Products and Colorectal Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. Nutrients, 13(9), [3132]. https://doi.org/10.3390/nu13093132
    • Geraets, A. F. J., Köhler, S., Jansen, J. F. A., Eussen, S. J. P. M., Stehouwer, C. D. A., Schaper, N. C., Wesselius, A., Verhey, F. R. J., & Schram, M. T. (2021). The association of markers of cerebral small vessel disease and brain atrophy with incidence and course of depressive symptoms-the maastricht study. Journal of Affective Disorders, 292, 439-447. https://doi.org/10.1016/j.jad.2021.05.096
    • van Dongen, K. C. W., Linkens, A. M. A., Wetzels, S. M. W., Wouters, K., Vanmierlo, T., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., de Vos, W. M., Belzer, C., & Schalkwijk, C. G. (2021). Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in mice; evidence for reversibility. Food Research International, 147, [110547]. https://doi.org/10.1016/j.foodres.2021.110547
    • Schmieder, R. E., Mahfoud, F., Mancia, G., Azizi, M., Boehm, M., Dimitriadis, K., Kario, K., Kroon, A. A., Lobo, M. D., Ott, C., Pathak, A., Persu, A., Scalise, F., Schlaich, M., Kreutz, R., Tsioufis, C., & ESH Working Group on Device-Based Treatment of Hypertension (2021). European Society of Hypertension position paper on renal denervation 2021. Journal of Hypertension, 39(9), 1733-1741. https://doi.org/10.1097/HJH.0000000000002933
    • Piazza, M., Hanssen, N. M. J., Persson, F., Scheijen, J. L., van de Waarenburg, M. P. H., van Greevenbroek, M. M. J., Rossing, P., Hovind, P., Stehouwer, C. D. A., Parving, H-H., & Schalkwijk, C. G. (2021). Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study. Diabetic Medicine, 38(9), [14405]. https://doi.org/10.1111/dme.14405
    • Vosa, U., Claringbould, A., Westra, H. J., Bonder, M. J., Deelen, P., Zeng, B., Kirsten, H., Saha, A., Kreuzhuber, R., Yazar, S., Brugge, H., Oelen, R., de Vries, D. H., van der Wijst, M. G. P., Kasela, S., Pervjakova, N., Alves, I., Fave, M. J., Agbessi, M., ... Stehouwer, C. D. A. (2021). Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nature Genetics, 53(9), 1300-1310. https://doi.org/10.1038/s41588-021-00913-z
    • Schram, M. T., Assendelft, W. J. J., van Tilburg, T. G., & Dukers-Muijrers, N. H. T. M. (2021). Social networks and type 2 diabetes: a narrative review. Diabetologia, 64(9), 1905-1916. https://doi.org/10.1007/s00125-021-05496-2
    • De Clerck, E. E. B., Schouten, J. S. A. G., Berendschot, T. T. J. M., Goezinne, F., Liesenborghs, I., Dagnelie, P. C., Schaper, N. C., Kroon, A. A., Henry, R. M. A., Reesink, K. D., Schram, M. T., Stehouwer, C. D. A., & Webers, C. A. B. (2021). Vascular risk factors for optical coherence tomography-detected macular cysts: The Maastricht Study. Acta Ophthalmologica, 99(6), e860-e868. https://doi.org/10.1111/aos.14677
    • Wouters, K., Cento, A. S., Gaens, K. H., Teunissen, M., Scheijen, J. L. J. M., Barutta, F., Chiazza, F., Collotta, D., Aragno, M., Gruden, G., Collino, M., Schalkwijk, C. G., & Mastrocola, R. (2021). Deletion of RAGE fails to prevent hepatosteatosis in obese mice due to impairment of other AGEs receptors and detoxifying systems. Scientific Reports, 11(1), [17373]. https://doi.org/10.1038/s41598-021-96859-7
    • Mayen, A-L., Aglago, E. K., Knaze, V., Cordova, R., Schalkwijk, C. G., Wagner, K-H., Aleksandrova, K., Fedirko, V., Keski-Rahkonen, P., Leitzmann, M. F., Katzke, V., Srour, B., Schulze, M. B., Masala, G., Krogh, V., Panico, S., Tumino, R., Bueno-de-Mesquita, B., Brustad, M., ... Freisling, H. (2021). Dietary intake of advanced glycation endproducts and risk of hepatobiliary cancers: A multinational cohort study. International Journal of Cancer, 149(4), 854-864. https://doi.org/10.1002/ijc.33612
    • Empana, J. P., Boutouyrie, P., Lemogne, C., Jouven, X., & van Sloten, T. T. (2021). Microvascular Contribution to Late-Onset Depression: Mechanisms, Current Evidence, Association With Other Brain Diseases, and Therapeutic Perspectives. Biological Psychiatry, 90(4), 214-225. https://doi.org/10.1016/j.biopsych.2021.04.012
    • Monereo-Sanchez, J., de Jong, J. J. A., Drenthen, G. S., Beran, M., Backes, W. H., Stehouwer, C. D. A., Schram, M. T., Linden, D. E. J., & Jansen, J. F. A. (2021). Quality control strategies for brain MRI segmentation and parcellation: Practical approaches and recommendations- insights from the Maastricht study. Neuroimage, 237, [118174]. https://doi.org/10.1016/j.neuroimage.2021.118174