• 2023
    • van den Eynde, M. D. G., Houben, A. J. H. M., Scheijen, J. L. J. M., Linkens, A. M. A., Niessen, P. M., Simons, N., Hanssen, N. M. J., Kusters, Y. H. A. M., Eussen, S. J. M. P., Miyata, T., Stehouwer, C. D. A., & Schalkwijk, C. G. (2023). Pyridoxamine reduces methylglyoxal and markers of glycation and endothelial dysfunction, but does not improve insulin sensitivity or vascular function in abdominally obese individuals: A randomized double-blind placebo-controlled trial. Diabetes Obesity & Metabolism, 25(5), 1280-1291. https://doi.org/10.1111/dom.14977
    • de Ritter, R., Sep, S. J. S., van Greevenbroek, M. M. J., Kusters, Y. H. A. M., Vos, R. C., Bots, M. L., Kooi, M. E., Dagnelie, P. C., Eussen, S. J. P. M., Schram, M. T., Koster, A., Brouwers, M. C. G., van der Sangen, N. M. R., Peters, S. A. E., van der Kallen, C. J. H., & Stehouwer, C. D. A. (2023). Sex differences in body composition in people with prediabetes and type 2 diabetes as compared with people with normal glucose metabolism: the Maastricht Study. Diabetologia, 66(5), 861-872. https://doi.org/10.1007/s00125-023-05880-0
    • Vandercappellen, E. J., Koster, A., Savelberg, H. H. C. M., Eussen, S. J. P. M., Dagnelie, P. C., Schram, M. T., van Greevenbroek, M. M. J., Wesselius, A., Kooman, J. P., Kroon, A. A., Henry, R. M. A., & Stehouwer, C. D. A. (2023). Accelerometer-derived physical activity and sedentary time and cardiac biomarkers: The Maastricht Study. Frontiers in Cardiovascular Medicine, 10(1), Article 1081713. https://doi.org/10.3389/fcvm.2023.1081713
    • Buziau, A. M., Blokland, G. A. M., Schalkwijk, C. G., Scheijen, J. L. J. M., Simons, P. I. H. G., Eussen, S. J. P. M., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2023). Comment on Lee et al. Relation of Change or Substitution of Low- and No-Calorie Sweetened Beverages With Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Prospective Cohort Studies. Diabetes Care 2022;45. Diabetes Care, 46(4), E97-E98. https://doi.org/10.2337/dc22-1930
    • van den Kerkhof, M., van der Thiel, M. M., Postma, A. A., van Oostenbrugge, R. J., Kroon, A. A., Jansen, J. F. A., & Backes, W. H. (2023). Hypertension Correlates With Stronger Blood Flow Pulsatility in Small Perforating Cerebral Arteries Assessed With 7 Tesla Magnetic Resonance Imaging. Hypertension, 80(4), 802-810. https://doi.org/10.1161/HYPERTENSIONAHA.122.19866
    • Zhang, X. D., Scheijen, J. L. J. M., Stehouwer, C. D. A., Wouters, K., & Schalkwijk, C. G. (2023). Increased methylglyoxal formation in plasma and tissues during a glucose tolerance test is derived from exogenous glucose. Clinical Science, 137(8), 697-706. https://doi.org/10.1042/CS20220753
    • Alnazer, R. M., Veldhuizen, G. P., de Leeuw, P. W., & Kroon, A. A. (2023). The effect of age, sex and BMI on the aldosterone-to-renin ratio in essential hypertensive individuals. Journal of Hypertension, 41(4), 618-623. https://doi.org/10.1097/HJH.0000000000003377
    • DeJong, N. R., Jansen, J. F. A., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., Dagnelie, P. C., van der Kallen, C. J. H., Kroon, A. A., Wesselius, A., Koster, A., Backes, W. H., & Kohler, S. (2023). Cognitive resilience depends on white matter connectivity: The Maastricht Study. Alzheimer's & Dementia, 19(4), 1164-1174. https://doi.org/10.1002/alz.12758
    • Veldhuizen, G. P., Alnazer, R. M., de Leeuw, P. W., & Kroon, A. A. (2023). The Effects of Verapamil, Hydralazine, and Doxazosin on Renin, Aldosterone, and the Ratio Thereof. Cardiovascular Drugs and Therapy, 37(2), 283-289. https://doi.org/10.1007/s10557-021-07262-3
    • van der Heide, F. C. T., Eussen, S. J. P. M., Houben, A. J. H. M., Henry, R. M. A., Kroon, A. A., van der Kallen, C. J. H., Dagnelie, P. C., van Dongen, M. C. J. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Koster, A., Jansen, J. F. A., Backes, W. H., Beulens, J. W. J., & Stehouwer, C. D. A. (2023). Alcohol consumption and microvascular dysfunction: a J-shaped association: The Maastricht Study. Cardiovascular Diabetology, 22(1), Article 67. https://doi.org/10.1186/s12933-023-01783-x
    • Paschos, S., Lize, N., Eussen, S., van der Padt-pruijsten, A., van den Beuken-van Everdingen, M., van Laarhoven, H., den Boer, M., de Graeff, A., van den Borne, B., ten Have, H., Kennis, M., Beijer, S., Raijmakers, N. J. H., & van de Poll-franse, L. (2023). Are gastrointestinal problems, nutritional care, and nutritional care needs associated with quality of life in patients with advanced cancer? Results of the observational eQuiPe study. Supportive Care in Cancer, 31(3), Article 189. https://doi.org/10.1007/s00520-023-07646-1
    • Tore, E. C., Elshorbagy, A. K., Bakers, F. C. H., Brouwers, M. C. G. J., Dagnelie, P. C., Eussen, S. J. P. M., Jansen, J. F. A., Kooi, M. E., Kusters, Y. H. A. M., Meex, S. J. R., Olsen, T., Refsum, H., Retterstøl, K., Schalkwijk, C. G., Stehouwer, C. D. A., Vinknes, K. J., & van Greevenbroek, M. M. J. (2023). Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study. European Journal of Nutrition, 62(2), 891-904. https://doi.org/10.1007/s00394-022-03041-4
    • Buziau, A. M., Law, P. J., Blokland, G., Schalkwijk, C., Scheijen, J., Simons, P., van der Kallen, C., Eussen, S., Dagnelie, P. C., van Greevenbroek, M., Houlston, R. S., Wesselius, A., Went, M., Stehouwer, C., & Brouwers, M. C. (2023). Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study. Gut, 72(3), 604-606. https://doi.org/10.1136/gutjnl-2021-326299
    • van Yperen, N. C., Wauben, B., van der Poel, M. W., Köhler, S., van Greevenbroek, M. M., & Schouten, H. C. (2023). Selection bias in follow-up studies of stem cell transplantation survivors: an experience within the Maastricht Observational study of late effects after Stem cell trAnsplantation (MOSA). Annals of Hematology, 102(3), 641-649. https://doi.org/10.1007/s00277-022-05070-9
    • Gianfredi, V., Dinu, M., Nucci, D., Eussen, S. J. P. M., Amerio, A., Schram, M. T., Schaper, N., & Odone, A. (2023). Association between dietary patterns and depression: an umbrella review of meta-analyses of observational studies and intervention trials. Nutrition Reviews, 81(3), 346-359. https://doi.org/10.1093/nutrit/nuac058
    • van Gennip, A. C. E., Schram, M., Kohler, S., Kroon, A. A., Koster, A., Eussen, S. J. P. M., de Galan, B. E., van Sloten, T. T., & Stehouwer, C. D. A. (2023). Association of type 2 diabetes according to the number of risk factors within the recommended range with incidence of major depression and clinically relevant depressive symptoms: a prospective analysis. The Lancet Healthy Longevity, 4(2), e63-e71. https://doi.org/10.1016/S2666-7568(22)00291-4
    • Dekkers, K. F., Slieker, R. C., Ioan-Facsinay, A., van Iterson, M., Ikram, M. A., van Greevenbroek, M. M. J., Veldink, J. H., Franke, L., Boomsma, D. I., Slagboom, P. E., Jukema, J. W., Heijmans, B. T., & BIOS Consortium (2023). Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response. Nature Communications, 14(1), Article 544. https://doi.org/10.1038/s41467-022-35663-x
    • Hanssen, N. M. J., Tikellis, C., Pickering, R. J., Dragoljevic, D., Lee, M. K. S., Block, T., Scheijen, J. L. J. M., Wouters, K., Miyata, T., Cooper, M. E., Murphy, A. J., Thomas, M. C., & Schalkwijk, C. G. (2023). Pyridoxamine prevents increased atherosclerosis by intermittent methylglyoxal spikes in the aortic arches of ApoE-/- mice. Biomedicine & Pharmacotherapy, 158(1), Article 114211. https://doi.org/10.1016/j.biopha.2022.114211
    • Zhou, T. L., Reulen, J. P. H., Van Der Staaij, H., Stehouwer, C. D. A., Van Greevenbroek, M., Henry, R. M. A., & Kroon, A. A. (2023). Cardiovagal baroreflex sensitivity, blood pressure and blood pressure variability - the Maastricht study. Journal of Hypertension, 41(2), 254-261. https://doi.org/10.1097/HJH.0000000000003323
    • Nguyen, B. O., Weberndorfer, V., Crijns, H. J. G. M., Geelhoed, B., Ten Cate, H., Spronk, H., Kroon, A., De With, R., Al-Jazairi, M., Maass, A. H., Blaauw, Y., Tieleman, R. G., Hemels, M. E. W., Luermans, J., de Groot, J., Allaart, C. P., Elvan, A., De Melis, M., Scheerder, C., ... Rienstra, M. (2023). Prevalence and determinants of atrial fibrillation progression in paroxysmal atrial fibrillation. Heart, 109(3), 186-194. https://doi.org/10.1136/heartjnl-2022-321027
    • Zhou, T. L., Schutten, M. T. J., Kroon, A. A., Henry, R. M. A., Houben, A. J. H. M., van der Kallen, C. J. H., van Greevenbroek, M. M. J., de Leeuw, P. W., & Stehouwer, C. D. A. (2023). Urinary Sodium Excretion and Salt Intake Are Not Associated With Blood Pressure Variability in a White General Population. Journal of the American Heart Association, 12(1), Article e026578. https://doi.org/10.1161/JAHA.122.026578
    • Schalkwijk, C. G., Micali, L. R., & Wouters, K. (2023). Advanced glycation endproducts in diabetes-related macrovascular complications: focus on methylglyoxal. Trends in Endocrinology and Metabolism, 34(1), 49-60. https://doi.org/10.1016/j.tem.2022.11.004
    • Monereo-Sánchez, J., Jansen, J. F. A., Köhler, S., van Boxtel, M. P. J., Backes, W. H., Stehouwer, C. D. A., Kroon, A. A., Kooman, J. P., Schalkwijk, C. G., Linden, D. E. J., & Schram, M. T. (2023). The association of prediabetes and type 2 diabetes with hippocampal subfields volume: The Maastricht study. NeuroImage: Clinical, 39, Article 103455. https://doi.org/10.1016/j.nicl.2023.103455
    • Ren, Z., Simons, P. I. H. G., Wesselius, A., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2023). Relationship between NAFLD and coronary artery disease: A Mendelian randomization study. Hepatology, 77(1), 230-238. https://doi.org/10.1002/hep.32534
    • Simons, P. I. H. G., Valkenburg, O., van de Waarenburg, M. P. H., van Greevenbroek, M. M. J., Kooi, M. E., Jansen, J. F. A., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2023). Serum sex hormone-binding globulin is a mediator of the association between intrahepatic lipid content and type 2 diabetes: the Maastricht Study. Diabetologia, 66(1), 213-222. https://doi.org/10.1007/s00125-022-05790-7
    • Cobussen, M., Verhave, J. C., Buijs, J., & Stassen, P. M. (2023). The incidence and outcome of AKI in patients with sepsis in the emergency department applying different definitions of AKI and sepsis. International Urology and Nephrology, 55(1), 183-190. https://doi.org/10.1007/s11255-022-03267-5
    • de Graaf, M. C. G., Scheijen, J. L. J. M., Spooren, C. E. G. M., Mujagic, Z., Pierik, M. J., Feskens, E. J. M., Keszthelyi, D., Schalkwijk, C. G., & Jonkers, D. M. A. E. (2023). The Intake of Dicarbonyls and Advanced Glycation Endproducts as Part of the Habitual Diet Is Not Associated with Intestinal Inflammation in Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients. Nutrients, 15(1), Article 83. https://doi.org/10.3390/nu15010083
    • Zeijen, V. J. M., Kroon, A. A., van den Born, B. H., Blankestijn, P. J., Meijvis, S. C. A., Nap, A., Lipsic, E., Elvan, A., Versmissen, J., van Geuns, R. J., Voskuil, M., Tonino, P. A. L., Spiering, W., Deinum, J., & Daemen, J. (2023). The position of renal denervation in treatment of hypertension: an expert consensus statement. Netherlands Heart Journal, 31(1), 3-11. https://doi.org/10.1007/s12471-022-01717-4
    • Fontaine, M. A. C., Jin, H., Gagliardi, M., Rousch, M., Wijnands, E., Stoll, M., Li, X., Schurgers, L., Reutelingsperger, C., Schalkwijk, C., van den Akker, N. M. S., Molin, D. G. M., Gullestad, L., Eritsland, J., Hoffman, P., Skjelland, M., Andersen, G. Ø., Aukrust, P., Karel, J., ... Biessen, E. A. L. (2023). Blood Milieu in Acute Myocardial Infarction Reprograms Human Macrophages for Trauma Repair. Advanced Science, 10(5), Article 2203053. https://doi.org/10.1002/advs.202203053
    • Tichler, A., Hertroijs, D. F., Ruwaard, D., Brouwers, M. C., Hiligsmann, M., de Jong, J. D., & Elissen, A. M. (2023). Preferred Conversation Topics with Respect to Treatment Decisions Among Individuals with Type 2 Diabetes. Patient Preference and Adherence, 17(1), 719-729. https://doi.org/10.2147/PPA.S397647
    • van der Heide, F. C. T., Mokhtar, S., Khanna, A., Said, M., Henry, R. M. A., Kroon, A. A., Dagnelie, P. C., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Savelberg, H. H. C. M., Schaper, N. C., Webers, C. A. B., & Stehouwer, C. D. A. (2023). Retinal Functional and Structural Neural Indices: Potential Biomarkers for the Monitoring of Cerebral Neurodegeneration: The Maastricht Study. Journal of Alzheimer's Disease, 93(4), 1471-1483. https://doi.org/10.3233/JAD-230104
  • 2022
    • Maasen, K., Eussen, S. J. P. M., Dagnelie, P. C., Houben, A. J. H. M., Webers, C. A. B., Schram, M. T., Berendschot, T. T. J. M., Stehouwer, C. D. A., Opperhuizen, A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2022). Habitual intake of dietary methylglyoxal is associated with less low-grade inflammation: the Maastricht Study. American Journal of Clinical Nutrition, 116(6), 1715-1728. https://doi.org/10.1093/ajcn/nqac195
    • Gulpers, B. J. A., Verhey, F. R. J., Eussen, S. J. P. M., Schram, M. T., de Galan, B. E., van Boxtel, M. P. J., Stehouwer, C. D. A., & Köhler, S. (2022). Anxiety and cognitive functioning in the Maastricht study: A cross-sectional population study. Journal of Affective Disorders, 319, 570-579. https://doi.org/10.1016/j.jad.2022.09.072
    • Holthuijsen, D. D. B., Bours, M. J. L., Roekel, E. H. V., Breukink, S. O., Janssen-Heijnen, M. L. G., Keulen, E. T. P., Ueland, P. M., Midttun, Ø., Brezina, S., Gigic, B., Gsur, A., Kok, D. E., Ose, J., Ulrich, C. M., Weijenberg, M. P., & Eussen, S. J. P. M. (2022). Longitudinal Associations of Adherence to the Dietary World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) and Dutch Healthy Diet (DHD) Recommendations with Plasma Kynurenines in Colorectal Cancer Survivors after Treatment. Nutrients, 14(23), Article 5151. https://doi.org/10.3390/nu14235151
    • Odintsova, V. V., Suderman, M., Hagenbeek, F. A., Caramaschi, D., Hottenga, J. J., Pool, R., Dolan, C. V., Ligthart, L., van Beijsterveldt, C. E. M., Willemsen, G., de Geus, E. J. C., Beck, J. J., Ehli, E. A., Cuellar-Partida, G., Evans, D. M., Medland, S. E., Relton, C. L., Boomsma, D. I., van Dongen, J., ... Management Team (2022). DNA methylation in peripheral tissues and left-handedness. Scientific Reports, 12(1), Article 5606. https://doi.org/10.1038/s41598-022-08998-0
    • Simons, P. I. H. G., Valkenburg, O., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Association between de novo lipogenesis susceptibility genes and coronary artery disease. Nutrition Metabolism and Cardiovascular Diseases, 32(12), 2883-2889. https://doi.org/10.1016/j.numecd.2022.09.003
    • Gianfredi, V., Schaper, N. C., Odone, A., Signorelli, C., Amerio, A., Eussen, S. J. P. M., Köhler, S., Savelberg, H. H. C. M., Stehouwer, C. D. A., Dagnelie, P. C., Henry, R. M. A., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Schram, M. T., & Koster, A. (2022). Daily patterns of physical activity, sedentary behavior, and prevalent and incident depression-The Maastricht Study. Scandinavian Journal of Medicine & Science in Sports, 32(12), 1768-1780. https://doi.org/10.1111/sms.14235
    • Zelis, N., Roumans-van Oijen, A. M. M., Buijs, J., van Kraaij, D. J. W., van Kuijk, S. M. J., de Leeuw, P. W., & Stassen, P. M. (2022). Major adverse cardiovascular events in older emergency department patients presenting with non-cardiac medical complaints. Netherlands Heart Journal, 30(12), 559-566. https://doi.org/10.1007/s12471-022-01700-z
    • Empana, J.-P., Lerner, I., Perier, M.-C., Guibout, C., Jabre, P., Bailly, K., Andrieu, M., Climie, R., van Sloten, T., Vedie, B., Geromin, D., Marijon, E., Thomas, F., Danchin, N., Boutouyrie, P., & Jouven, X. (2022). Ultrasensitive Troponin I and Incident Cardiovascular Disease. Arteriosclerosis Thrombosis and Vascular Biology, 42(12), 1471-1481. https://doi.org/10.1161/atvbaha.122.317961
    • Ren, Z. W., Simons, P. I. H. G., Wesselius, A., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Untitled Reply. Hepatology, 76(6), E129-E130. https://doi.org/10.1002/hep.32611
    • van der Heide, F. C. T., van Sloten, T. T., Willekens, N., & Stehouwer, C. D. A. (2022). Neurovascular coupling unit dysfunction and dementia: Retinal measurements as tools to move towards population-based evidence. Frontiers in Endocrinology, 13, Article 1014287. https://doi.org/10.3389/fendo.2022.1014287
    • Csongová, M., Scheijen, J. L. J. M., van de Waarenburg, M. P. H., Gurecká, R., Koborová, I., Tábi, T., Szökö, É., Schalkwijk, C. G., & Šebeková, K. (2022). Association of α-Dicarbonyls and Advanced Glycation End Products with Insulin Resistance in Non-Diabetic Young Subjects: A Case-Control Study. Nutrients, 14(22). https://doi.org/10.3390/nu14224929
    • Yu, E. Y.-W., Ren, Z., Mehrkanoon, S., Stehouwer, C. D. A., van Greevenbroek, M. M. J., Eussen, S. J. P. M., Zeegers, M. P., & Wesselius, A. (2022). Plasma metabolomic profiling of dietary patterns associated with glucose metabolism status: The Maastricht Study. BMC Medicine, 20(1), 450. https://doi.org/10.1186/s12916-022-02653-1
    • De Hert, E., Verboven, K., Wouters, K., Jocken, J. W. E., & De Meester, I. (2022). Prolyl Carboxypeptidase Activity Is Present in Human Adipose Tissue and Is Elevated in Serum of Obese Men with Type 2 Diabetes. International journal of molecular sciences, 23(21), Article 13529. https://doi.org/10.3390/ijms232113529
    • Veldhuizen, G. P., Alnazer, R. M., Kroon, A. A., & de Leeuw, P. W. (2022). Variability of aldosterone, renin and the aldosterone-to-renin ratio in hypertensive patients without primary aldosteronism. Journal of Hypertension, 40, 2256-2262. https://doi.org/10.1097/HJH.0000000000003257
    • Jin, S., Reesink, K. D., Kroon, A. A., de Galan, B., van der Kallen, C. J. H., Wesselius, A., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2022). Complement factors D and C3 cross-sectionally associate with arterial stiffness, but not independently of metabolic risk factors: The Maastricht Study. Journal of Hypertension, 40(11), 2161-2170. https://doi.org/10.1097/HJH.0000000000003237
    • Wölfel, E. M., Schmidt, F. N., Vom Scheidt, A., Siebels, A. K., Wulff, B., Mushumba, H., Ondruschka, B., Püschel, K., Scheijen, J., Schalkwijk, C. G., Vettorazzi, E., Jähn-Rickert, K., Gludovatz, B., Schaible, E., Amling, M., Rauner, M., Hofbauer, L. C., Zimmermann, E. A., & Busse, B. (2022). Dimorphic mechanisms of fragility in diabetes mellitus - the role of reduced collagen fibril deformation. Journal of Bone and Mineral Research, 37(11), 2259-2276. https://doi.org/10.1002/jbmr.4706
    • Geraets, A. F. J., Schram, M. T., Jansen, J. F. A., Koster, A., Dagnelie, P. C., van Greevenbroek, M. M. J., Stehouwer, C. D. A., Verhey, F. R. J., & Köhler, S. (2022). The relation of depression with structural brain abnormalities and cognitive functioning: the Maastricht study. Psychological Medicine, 52(15), 3521–3530. https://doi.org/10.1017/S0033291721000222
    • van der Heide, F. C. T., Foreman, Y. D., Franken, I. W. M., Henry, R. M. A., Kroon, A. A., Dagnelie, P. C., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Schaper, N. C., Brouwers, M. C. G. J., & Stehouwer, C. D. A. (2022). (Pre)diabetes, glycemia, and daily glucose variability are associated with retinal nerve fiber layer thickness in The Maastricht Study. Scientific Reports, 12(1), Article 17750. https://doi.org/10.1038/s41598-022-22748-2