• 2022
    • Maasen, K., Eussen, S. J. P. M., Dagnelie, P. C., Houben, A. J. H. M., Webers, C. A. B., Schram, M. T., Berendschot, T. T. J. M., Stehouwer, C. D. A., Opperhuizen, A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2022). Habitual intake of dietary methylglyoxal is associated with less low-grade inflammation: the Maastricht Study. American Journal of Clinical Nutrition, 116(6), 1715-1728. https://doi.org/10.1093/ajcn/nqac195
    • Gulpers, B. J. A., Verhey, F. R. J., Eussen, S. J. P. M., Schram, M. T., de Galan, B. E., van Boxtel, M. P. J., Stehouwer, C. D. A., & Köhler, S. (2022). Anxiety and cognitive functioning in the Maastricht study: A cross-sectional population study. Journal of Affective Disorders, 319, 570-579. https://doi.org/10.1016/j.jad.2022.09.072
    • Holthuijsen, D. D. B., Bours, M. J. L., Roekel, E. H. V., Breukink, S. O., Janssen-Heijnen, M. L. G., Keulen, E. T. P., Ueland, P. M., Midttun, Ø., Brezina, S., Gigic, B., Gsur, A., Kok, D. E., Ose, J., Ulrich, C. M., Weijenberg, M. P., & Eussen, S. J. P. M. (2022). Longitudinal Associations of Adherence to the Dietary World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) and Dutch Healthy Diet (DHD) Recommendations with Plasma Kynurenines in Colorectal Cancer Survivors after Treatment. Nutrients, 14(23), Article 5151. https://doi.org/10.3390/nu14235151
    • Odintsova, V. V., Suderman, M., Hagenbeek, F. A., Caramaschi, D., Hottenga, J. J., Pool, R., Dolan, C. V., Ligthart, L., van Beijsterveldt, C. E. M., Willemsen, G., de Geus, E. J. C., Beck, J. J., Ehli, E. A., Cuellar-Partida, G., Evans, D. M., Medland, S. E., Relton, C. L., Boomsma, D. I., van Dongen, J., ... Management Team (2022). DNA methylation in peripheral tissues and left-handedness. Scientific Reports, 12(1), Article 5606. https://doi.org/10.1038/s41598-022-08998-0
    • Simons, P. I. H. G., Valkenburg, O., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Association between de novo lipogenesis susceptibility genes and coronary artery disease. Nutrition Metabolism and Cardiovascular Diseases, 32(12), 2883-2889. https://doi.org/10.1016/j.numecd.2022.09.003
    • Gianfredi, V., Schaper, N. C., Odone, A., Signorelli, C., Amerio, A., Eussen, S. J. P. M., Köhler, S., Savelberg, H. H. C. M., Stehouwer, C. D. A., Dagnelie, P. C., Henry, R. M. A., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Schram, M. T., & Koster, A. (2022). Daily patterns of physical activity, sedentary behavior, and prevalent and incident depression-The Maastricht Study. Scandinavian Journal of Medicine & Science in Sports, 32(12), 1768-1780. https://doi.org/10.1111/sms.14235
    • Zelis, N., Roumans-van Oijen, A. M. M., Buijs, J., van Kraaij, D. J. W., van Kuijk, S. M. J., de Leeuw, P. W., & Stassen, P. M. (2022). Major adverse cardiovascular events in older emergency department patients presenting with non-cardiac medical complaints. Netherlands Heart Journal, 30(12), 559-566. https://doi.org/10.1007/s12471-022-01700-z
    • Yu, E. Y.-W., Ren, Z., Mehrkanoon, S., Stehouwer, C. D. A., van Greevenbroek, M. M. J., Eussen, S. J. P. M., Zeegers, M. P., & Wesselius, A. (2022). Plasma metabolomic profiling of dietary patterns associated with glucose metabolism status: The Maastricht Study. BMC Medicine, 20(1), 450. Article 450. https://doi.org/10.1186/s12916-022-02653-1
    • Empana, J.-P., Lerner, I., Perier, M.-C., Guibout, C., Jabre, P., Bailly, K., Andrieu, M., Climie, R., van Sloten, T., Vedie, B., Geromin, D., Marijon, E., Thomas, F., Danchin, N., Boutouyrie, P., & Jouven, X. (2022). Ultrasensitive Troponin I and Incident Cardiovascular Disease. Arteriosclerosis Thrombosis and Vascular Biology, 42(12), 1471-1481. https://doi.org/10.1161/atvbaha.122.317961
    • Ren, Z. W., Simons, P. I. H. G., Wesselius, A., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Untitled Reply. Hepatology, 76(6), E129-E130. https://doi.org/10.1002/hep.32611
    • van der Heide, F. C. T., van Sloten, T. T., Willekens, N., & Stehouwer, C. D. A. (2022). Neurovascular coupling unit dysfunction and dementia: Retinal measurements as tools to move towards population-based evidence. Frontiers in Endocrinology, 13, Article 1014287. https://doi.org/10.3389/fendo.2022.1014287
    • Csongová, M., Scheijen, J. L. J. M., van de Waarenburg, M. P. H., Gurecká, R., Koborová, I., Tábi, T., Szökö, É., Schalkwijk, C. G., & Šebeková, K. (2022). Association of α-Dicarbonyls and Advanced Glycation End Products with Insulin Resistance in Non-Diabetic Young Subjects: A Case-Control Study. Nutrients, 14(22), Article 4929. https://doi.org/10.3390/nu14224929
    • De Hert, E., Verboven, K., Wouters, K., Jocken, J. W. E., & De Meester, I. (2022). Prolyl Carboxypeptidase Activity Is Present in Human Adipose Tissue and Is Elevated in Serum of Obese Men with Type 2 Diabetes. International journal of molecular sciences, 23(21), Article 13529. https://doi.org/10.3390/ijms232113529
    • Veldhuizen, G. P., Alnazer, R. M., Kroon, A. A., & de Leeuw, P. W. (2022). Variability of aldosterone, renin and the aldosterone-to-renin ratio in hypertensive patients without primary aldosteronism. Journal of Hypertension, 40, 2256-2262. https://doi.org/10.1097/HJH.0000000000003257
    • Jin, S., Reesink, K. D., Kroon, A. A., de Galan, B., van der Kallen, C. J. H., Wesselius, A., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2022). Complement factors D and C3 cross-sectionally associate with arterial stiffness, but not independently of metabolic risk factors: The Maastricht Study. Journal of Hypertension, 40(11), 2161-2170. https://doi.org/10.1097/HJH.0000000000003237
    • Wölfel, E. M., Schmidt, F. N., Vom Scheidt, A., Siebels, A. K., Wulff, B., Mushumba, H., Ondruschka, B., Püschel, K., Scheijen, J., Schalkwijk, C. G., Vettorazzi, E., Jähn-Rickert, K., Gludovatz, B., Schaible, E., Amling, M., Rauner, M., Hofbauer, L. C., Zimmermann, E. A., & Busse, B. (2022). Dimorphic mechanisms of fragility in diabetes mellitus - the role of reduced collagen fibril deformation. Journal of Bone and Mineral Research, 37(11), 2259-2276. https://doi.org/10.1002/jbmr.4706
    • Geraets, A. F. J., Schram, M. T., Jansen, J. F. A., Koster, A., Dagnelie, P. C., van Greevenbroek, M. M. J., Stehouwer, C. D. A., Verhey, F. R. J., & Köhler, S. (2022). The relation of depression with structural brain abnormalities and cognitive functioning: the Maastricht study. Psychological Medicine, 52(15), 3521–3530. https://doi.org/10.1017/S0033291721000222
    • van der Heide, F. C. T., Foreman, Y. D., Franken, I. W. M., Henry, R. M. A., Kroon, A. A., Dagnelie, P. C., Eussen, S. J. P. M., Berendschot, T. T. J. M., Schouten, J. S. A. G., Webers, C. A. B., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Schaper, N. C., Brouwers, M. C. G. J., & Stehouwer, C. D. A. (2022). (Pre)diabetes, glycemia, and daily glucose variability are associated with retinal nerve fiber layer thickness in The Maastricht Study. Scientific Reports, 12(1), Article 17750. https://doi.org/10.1038/s41598-022-22748-2
    • Konopka, M. J., Kohler, S., Stehouwer, C. D. A., Schaper, N. C., Henry, R. M. A., van der Kallen, C. J. H., Savelberg, H. H. C. M., Eussen, S. J. P. M., Dagniele, P. C., van Dongen, M. C. J. M., Schram, M. T., & Koster, A. (2022). Accelerometer-derived sedentary time and physical activity and the incidence of depressive symptoms - The Maastricht Study. Psychological Medicine, 52(13), 2786-2793. https://doi.org/10.1017/S0033291720004924
    • Spaetgens, B., Brouns, S. H. A., Linkens, A. E. M. J. H., Poeze, M., Ten Broeke, R. H. M., Brüggemann, R. A. G., Sipers, W., Henry, R. M. A., & Hanssen, N. M. J. (2022). Associations between presence of diabetes, mortality and fracture type in individuals with a hip fracture. Diabetes Research and Clinical Practice, 192, Article 110084. https://doi.org/10.1016/j.diabres.2022.110084
    • Córdova, R., Mayén, A.-L., Knaze, V., Aglago, E. K., Schalkwijk, C., Wagner, K.-H., Overvad, K., Tjønneland, A., Kyrø, C., Katzke, V. A., Cornet, C. L., Schulze, M. B., Birukov, A., Palli, D., Grioni, S., Pasanisi, F., Catalano, A., Sandanger, T. M., Gram, I. T., ... Freisling, H. (2022). Dietary intake of advanced glycation endproducts (AGEs) and cancer risk across more than 20 anatomical sites: A multinational cohort study. Cancer Communications, 42, 1041-1045. https://doi.org/10.1002/cac2.12343
    • Top, W. M. C., Lehert, P., Schalkwijk, C. G., Stehouwer, C. D. A., & Kooy, A. (2022). Effect of metformin on arginine and dimethylarginines in patients with advanced type 2 diabetes: A post hoc analysis of a randomized trial. Diabetes Obesity & Metabolism, 24(10), 1983-1988. https://doi.org/10.1111/dom.14784
    • Janssen, L. E. F., Simons, N., Simons, P. I. H. G., Schaper, N. C., Feskens, E. J. M., van der Ploeg, L. M. C., Van den Eynde, M. D. G., Schalkwijk, C. G., Houben, A. J. H. M., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Effects of fructose restriction on blood pressure: Secondary analysis of a double-blind randomized controlled trial. Clinical Nutrition ESPEN, 51, 97-103. https://doi.org/10.1016/j.clnesp.2022.07.009
    • Brouwers, M. C. G. J. (2022). Fructose 1-phosphate, an evolutionary signaling molecule of abundancy. Trends in Endocrinology and Metabolism, 33(10), 680-689. https://doi.org/10.1016/j.tem.2022.07.007
    • Sun, C., van Soest, J., Koster, A., Eussen, S. J. P. M., Schram, M. T., Stehouwer, C. D. A., Dagnelie, P. C., & Dumontier, M. (2022). Studying the association of diabetes and healthcare cost on distributed data from the Maastricht Study and Statistics Netherlands using a privacy-preserving federated learning infrastructure. Journal of Biomedical Informatics, 134, Article 104194. https://doi.org/10.1016/j.jbi.2022.104194
    • Pinxt, C. M. H., Bogie, R. M. M., Hanssen, N. M. J., & Spaetgens, B. (2022). COVID-19: a wake-up call for antibiotic overuse in older patients?QJM: An International Journal of Medicine, 115(9), 637-637. https://doi.org/10.1093/qjmed/hcab234
    • Geraets, A. F. J., Schram, M. T., Jansen, J. F. A., Backes, W. H., Schalkwijk, C. G., Stehouwer, C. D. A., van Boxtel, M. P. J., Eussen, S. J. P. M., Kooman, J. P., Verhey, F. R. J., & Köhler, S. (2022). The cardiometabolic depression subtype and its association with clinical characteristics: The Maastricht Study. Journal of Affective Disorders, 313, 110-117. https://doi.org/10.1016/j.jad.2022.06.045
    • Baylan, U., Korn, A., Emmens, R. W., Schalkwijk, C. G., Niessen, H. W. M., Krijnen, P. A. J., & Simsek, S. (2022). Liraglutide treatment attenuates inflammation markers in the cardiac, cerebral and renal microvasculature in streptozotocin-induced diabetic rats. European Journal of Clinical Investigation, 52(9), Article e13807. https://doi.org/10.1111/eci.13807
    • van Vliet, K., van Ginkel, W. G., Jahja, R., Daly, A., MacDonald, A., Santra, S., De Laet, C., Goyens, P. J., Vara, R., Rahman, Y., Cassiman, D., Eyskens, F., Timmer, C., Mumford, N., Gissen, P., Bierau, J., van Hasselt, P. M., Wilcox, G., Morris, A. A. M., ... van Spronsen, F. J. (2022). Neurocognitive outcome and mental health in children with tyrosinemia type 1 and phenylketonuria: A comparison between two genetic disorders affecting the same metabolic pathway. Journal of Inherited Metabolic Disease, 45(5), 952-962. https://doi.org/10.1002/jimd.12528
    • Koene, E., Schrauwen-Hinderling, V. B., Schrauwen, P., & Brouwers, M. C. G. J. (2022). Novel insights in intestinal and hepatic fructose metabolism: from mice to men. Current Opinion in Clinical Nutrition and Metabolic Care, 25(5), 354-359. https://doi.org/10.1097/MCO.0000000000000853
    • van Dinther, M., Voorter, P. H. M., Schram, M. T., Berendschot, T. T. J. M., Houben, A. J. H. M., Webers, C. A. B., van Oostenbrugge, R. J., Backes, W. H., Staals, J., & Jansen, J. F. A. (2022). Retinal microvascular function is associated with the cerebral microcirculation as determined by intravoxel incoherent motion MRI. Journal of the Neurological Sciences, 440, Article 120359. https://doi.org/10.1016/j.jns.2022.120359
    • Leung, S. S., Borg, D. J., McCarthy, D. A., Boursalian, T. E., Cracraft, J., Zhuang, A., Fotheringham, A. K., Flemming, N., Watkins, T., Miles, J. J., Groop, P.-H., Scheijen, J. L., Schalkwijk, C. G., Steptoe, R. J., Radford, K. J., Knip, M., & Forbes, J. M. (2022). Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells. Diabetes, 71(9), 1994-2008. https://doi.org/10.2337/db22-0177
    • Goossens, P., Lu, C., Cao, J., Gijbels, M. J., Karel, J. M. H., Wijnands, E., Claes, B. S. R., Fazzi, G. E., Hendriks, T. F. E., Wouters, K., Smirnov, E., van Zandvoort, M. J. M., Balluff, B., Cuypers, E., Donners, M. M. P. C., Heeren, R. M. A., & Biessen, E. A. L. (2022). Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context. Cell Metabolism, 34(8), 1214-1225.e6. https://doi.org/10.1016/j.cmet.2022.06.012
    • Zhang, X., Schalkwijk, C. G., & Wouters, K. (2022). Immunometabolism and the modulation of immune responses and host defense: A role for methylglyoxal?Biochimica et Biophysica Acta-Molecular Basis of Disease, 1868(8), Article 166425. https://doi.org/10.1016/j.bbadis.2022.166425
    • Latten, G., Claassen, L., Muris, J., Cals, J., & Stassen, P. (2022). Koorts op de HAP: vitals, beslisregels en niet-pluisgevoel. Huisarts en Wetenschap, 65(8), 21-25. https://doi.org/10.1007/s12445-022-1507-x
    • Barutta, F., Bellini, S., Guarrera, S., Matullo, G., Schalkwijk, C., Stehouwer, C. D., Chaturvedi, N., Soedamah-Muthu, S. S., Durazzo, M., & Gruden, G. (2022). Association of Serum MicroRNA-145-5p Levels with Microvascular Complications of Type 1 Diabetes: the EURODIAB Prospective Complications Study. Diabetes Research and Clinical Practice, 190, Article 109987. https://doi.org/10.1016/j.diabres.2022.109987
    • Haring, M. P. D., Peeks, F., Oosterveer, M. H., Brouwers, M. C. G. J., Hollak, C. E. M., Janssen, M. C. H., Langendonk, J. G., Rennings, A. J. M., Wagenmakers, M. A. E. M., Verkade, H. J., Derks, T. G. J., & de Meijer, V. E. (2022). High childhood serum triglyceride concentrations associate with hepatocellular adenoma development in patients with glycogen storage disease type Ia. JHEP Reports, 4(8), Article 100512. https://doi.org/10.1016/j.jhepr.2022.100512
    • Brouwers, M. C. G. J., Simons, N., Kooi, M. E., de Ritter, R., van Dongen, M. C. J. M., Eussen, S. J. P. M., Bekers, O., Kooman, J., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schram, M. T., Schaper, N. C., Schalkwijk, C. G., & Stehouwer, C. D. A. (2022). Intrahepatic lipid content is independently associated with soluble E-selectin levels: The Maastricht study. Digestive and Liver Disease, 54(8), 1038-1043. https://doi.org/10.1016/j.dld.2022.01.130
    • Wauben, B., van Yperen, N. C., van der Poel, M. W., Köhler, S., van Greevenbroek, M. M., & Schouten, H. C. (2022). Long-term effects after stem cell transplantation identified: design of the MOSA study. Journal of Clinical Epidemiology, 148, 10-16. https://doi.org/10.1016/j.jclinepi.2022.03.012
    • van Dalem, J., Werkman, N. C. C., van den Bergh, J. P., Rossi, B., Viggers, R., Eastell, R., Burden, A. M., Stehouwer, C. D. A., Klungel, O. H., Brouwers, M. C. G. J., & Driessen, J. H. M. (2022). Use of sodium-glucose co-transporter 2 inhibitors, changes in body mass index and risk of fracture: a population-based cohort study. Diabetes Research and Clinical Practice, 190, Article 109993. https://doi.org/10.1016/j.diabres.2022.109993
    • Clemmensen, K. K. B., Koster, A., Nielen, J. T. H., Dagnelie, P. C., Stehouwer, C. D. A., Bosma, H., Wesselius, A., Færch, K., & Eussen, S. J. P. M. (2022). Role of weekday variation on glucose, insulin, and triglyceride: A cross-sectional analysis from The Maastricht Study. Journal of Clinical Endocrinology & Metabolism, 107(8), E3145-E3151. https://doi.org/10.1210/clinem/dgac286
    • Machado-Fragua, M. D., Fayosse, A., Yerramalla, M. S., van Sloten, T. T., Tabak, A. G., Kivimaki, M., Sabia, S., & Singh-Manoux, A. (2022). Association of Metabolic Syndrome With Incident Dementia: Role of Number and Age at Measurement of Components in a 28-Year Follow-up of the Whitehall II Cohort Study. Diabetes Care, 45(9), 2127-2135. https://doi.org/10.2337/dc22-0206
    • Rebelos, E., Daniele, G., Campi, B., Saba, A., Koskensalo, K., Ihalainen, J., Saukko, E., Nuutila, P., Backes, W. H., Jansen, J. F. A., Dagnelie, P. C., Köhler, S., de Galan, B. E., van Sloten, T. T., Stehouwer, C. D. A., & Ferrannini, E. (2022). Circulating N-Acetylaspartate does not track brain NAA concentrations, cognitive function or features of small vessel disease in humans. Scientific Reports, 12(1), Article 11530. https://doi.org/10.1038/s41598-022-15670-0
    • Dimakakos, E., Gomatou, G., Catalano, M., Olinic, D. M., Spyropoulos, A. C., Falanga, A., Maraveyas, A., Liew, A., Schulman, S., Belch, J., Gerotziafas, G., Marschang, P., Cosmi, B., Spaak, J., Syrigos, K., Antic, D., Blinc, A., Boc, V., Boccardo, F., ... CANCER-COVID-19 THROMBOSIS COLLABORATIVE GROUP (2022). Thromboembolic Disease in Patients With Cancer and COVID-19: Risk Factors, Prevention and Practical Thromboprophylaxis Recommendations–State-of-the-Art. Anticancer Research, 42(7), 3261-3274. Article 15815. https://doi.org/10.21873/anticanres.15815
    • Jin, S., Kusters, Y. H. A. M., Houben, A. J. H. M., Plat, J., Joris, P. J., Mensink, R. P., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2022). A randomized diet-induced weight-loss intervention reduces plasma complement C3: Possible implication for endothelial dysfunction. Obesity, 30(7), 1401-1410. https://doi.org/10.1002/oby.23467
    • Ruiz, A., Sanchez, D., Lafuente, A., Ortega, G., Buendia, M., Papasey, J., Jimeno, S. Y., Badia, F. P., Palacio, M. E., Abdelnour, C., Ramirez-Torano, F., Maestu, F., Saez, M. E., Tarraga, L., Dagnelie, P. C., & Boada, M. (2022). Evaluation of the Feasibility, Safety and Efficacy of the Use of Intravenous Infusions of Adenosine Triphosphate (ATP) in People Affected by Moderate to Severe Alzheimer's Disease: A Double-Blind Masked Clinical Trial for Dose Finding. JPAD-Journal of prevention of alzheimers disease, 9(3), 425-434. https://doi.org/10.14283/jpad.2022.38
    • Stassen, P., & Westerman, D. (2022). Novice Doctors in the Emergency Department: A Scoping Review. Cureus Journal of Medical Science, 14(6), Article e26245. https://doi.org/10.7759/cureus.26245
    • Sharma, S., Katz, R., Ginsberg, C., Bullen, A., Vallon, V., Thomson, S., Moe, O. W., Hoofnagle, A. N., de Leeuw, P. W., Kroon, A. A., Houben, A. J. H. M., & Ix, J. H. (2022). Renal Clearance of Fibroblast Growth Factor-23 (FGF23) and its Fragments in Humans. Journal of Bone and Mineral Research, 37(6), 1170-1178. https://doi.org/10.1002/jbmr.4553
    • Simons, P. I. H. G., Valkenburg, O., Telgenkamp, I., van der Waaij, K. M., de Groot, D. M., Veeraiah, P., Bons, J. A. P., Derks, T. G. J., Schalkwijk, C. G., Schrauwen-Hinderling, V. B., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Serum sex hormone-binding globulin levels are reduced and inversely associated with intrahepatic lipid content and saturated fatty acid fraction in adult patients with glycogen storage disease type 1a. Journal of Endocrinological Investigation, 45(6), 1227-1234. https://doi.org/10.1007/s40618-022-01753-2
    • Doola, R., Deane, A. M., Barrett, H. L., Okano, S., Tolcher, D. M., Gregory, K., Coombes, J. S., Schalkwijk, C., Todd, A. S., Forbes, J. M., & Sturgess, D. J. (2022). The impact of a modified carbohydrate formula, and its constituents, on glycaemic control and inflammatory markers: A nested mechanistic sub-study. Journal of Human Nutrition and Dietetics, 35(3), 455-465. https://doi.org/10.1111/jhn.12959