Publications
- 2025
- Janssen, L. E. F., Hiligsmann, M., Timmer, C., van der Ploeg, L. M. C., Kerckhove, K. V., Cox, T., Heras, J. D. L., Cassiman, D., & Brouwers, M. C. G. J. (2025). Treatment preferences of adult patients with hereditary fructose intolerance: A discrete choice experiment. Molecular Genetics and Metabolism, 145(4), Article 109169. https://doi.org/10.1016/j.ymgme.2025.109169
- Nokin, M.-J., Bellier, J., Durieux, F., Peulen, O., Rademaker, G., Gabriel, M., Monseur, C., Charloteaux, B., Verbeke, L., van Laere, S., Roncarati, P., Herfs, M., Lambert, C., Scheijen, J., Schalkwijk, C., Colige, A., Caers, J., Delvenne, P., Turtoi, A., ... Bellahcene, A. (2025). Correction: Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer (vol 21, 11, 2019). Breast Cancer Research, 27(1), Article 99. https://doi.org/10.1186/s13058-025-02044-3
- Stobbe, A. Y., Oosterom-Eijmael, M. J. P., de Galan, B. E., Hermanides, J., Siegelaar, S. E., & Hulst, A. H. (2025). GLP1-agonisten en SGLT2-remmers. Nederlands Tijdschrift voor Geneeskunde, 169, Article D8442. https://www.ntvg.nl/artikelen/glp1-agonisten-en-sglt2-remmers
- Chan, J. A., Koster, A., Lakerveld, J., Schram, M. T., van Greevenbroek, M., & Bosma, H. (2025). Correction to: Associations of neighborhood social cohesion and changes in BMI-The Maastricht Study. European journal of public health, 35(3), 583. Article ckae170. https://doi.org/10.1093/eurpub/ckae170
- Kashani, A. H., Berendschot, T. T. J. M., Bonnin, S., Sobrin, L., De Jesus, D. A., Brea, L. S., Martinez, A. C., Raman, R., de Vries, V. A., Huang, H., MacGillivray, T., Ramdas, W. D., van der Heide, F. C. T., & E3 consortium (2025). Retinal optical coherence tomography angiography imaging in population studies for study of microvascular dysfunction in Alzheimer's disease and related dementias. Alzheimer's & Dementia, 21(6), Article e70252. https://doi.org/10.1002/alz.70252
- Mohammad, A. K., Hugtenburg, J. G., Ceylan, Y., Kooij, M., Knies, S., van den Bemt, P. M. L. A., Denig, P., & Karapinar-Carkit, F. (2025). Pharmacy-led interventions to reverse and prevent prescribing cascades in primary care: a proof-of-concept study. International Journal of Clinical Pharmacy, 47(3), 784-793. Article e0272418. https://doi.org/10.1007/s11096-025-01873-8
- Nielen, J. T. H., van der Walle, K., Spronk, S., Magdelijns, F., Denig, P., & Karapinar, F. (2025). Real-World Complexity of Prescribing Cascades. Basic & Clinical Pharmacology & Toxicology, 137(1), Article e70063. https://doi.org/10.1111/bcpt.70063
- van Bree, B. E., van der Heijden, D. M. B., van Golde, R. J. T., Brouwers, M. C. G. J., Spaanderman, M. E. A., & Valkenburg, O. (2025). Sex hormone-binding globulin as a biomarker for metabolic risk in European women with polycystic ovary syndrome. Gynecological Endocrinology, 41(1), Article 2500462. https://doi.org/10.1080/09513590.2025.2500462
- Fabricius, T. W., Verhulst, C., Svensson, C. H., Wienberg, M., Duijnhouwer, A. L., Tack, C. J., Kristensen, P. L., de Galan, B. E., Pedersen-Bjergaard, U., & Hypo-RESOLVE Consortium (2025). Effects of insulin-induced hypoglycaemia on cardiac function in people with type 1 and type 2 diabetes and people without diabetes. Diabetes Obesity & Metabolism, 27(5), 2768-2776. https://doi.org/10.1111/dom.16283
- Zhang, X., van Greevenbroek, M. M. J., Scheijen, J. L. J. M., Eussen, S. J. P. M., Kelly, J., Stehouwer, C. D. A., Schalkwijk, C. G., & Wouters, K. (2025). Fasting plasma methylglyoxal concentrations are associated with higher numbers of circulating intermediate and non-classical monocytes but with lower activation of intermediate monocytes: the Maastricht Study. Journal of Endocrinological Investigation, 48(5), 1257-1268. https://doi.org/10.1007/s40618-025-02536-1
- Chen, H., Simons, P. I. H. G., & Brouwers, M. C. G. J. (2025). Is cardiovascular disease in PCOS driven by MASLD?Trends in Endocrinology and Metabolism, 36(5), 389-391. https://doi.org/10.1016/j.tem.2024.10.005
- Holthuijsen, D. D. B., Rijnhart, J. J. M., Bours, M. J. L., van Roekel, E. H., Ueland, P. M., Breukink, S. O., Janssen-Heijnen, M. L. G., Konsten, J. L., Keulen, E. T. P., McCann, A., Brezina, S., Gigic, B., Ulrich, C. M., Weijenberg, M. P., & Eussen, S. J. P. M. (2025). Longitudinal associations of dietary intake with fatigue in colorectal cancer survivors up to 1 year post-treatment, and the potential mediating role of the kynurenine pathway. Brain Behavior and Immunity, 126, 144-159. https://doi.org/10.1016/j.bbi.2025.02.003
- Mourmans, S. G. J., Achten, A., Hermans, R., Scheepers, M. J. E., D'Alessandro, E., Swennen, G., Woudstra, J., Appelman, Y., Goor, H. V., Schalkwijk, C., Knackstedt, C., Weerts, J., Eringa, E. C., & van Empel, V. P. M. (2025). The effect of empagliflozin on peripheral microvascular dysfunction in patients with heart failure with preserved ejection fraction. Cardiovascular Diabetology, 24(1), Article 182. https://doi.org/10.1186/s12933-025-02679-8
- Claassen, L., Stassen, P. M., Boumans, T. J. T., Barten, D. G., Kremers, M. N. T., Hermans, A. M. E., Zelis, N., Cals, J. W. L., & Latten, G. H. P. (2025). Characteristics of Dutch ED patients and their journey through the acute care chain: A province-wide flash-mob study. PLOS ONE, 20(4), Article e0318510. https://doi.org/10.1371/journal.pone.0318510
- Doola, R., Griffin, A., Forbes, J. M., Kruger, P. S., Deane, A. M., Schalkwijk, C. G., & White, K. C. (2025). Association between enteral carboxymethyllysine intake and daily glycemic variability in critically ill adults: A retrospective cohort study. Journal of Parenteral and Enteral Nutrition, 49(3), 324-331. https://doi.org/10.1002/jpen.2727
- Steens, I. L. M., Ji, Y., Sedaghat, S., Pankow, J., Klein, B. E. K., Cotch, M. F., Mcclelland, R. L., Hayden, K. M., Hughes, T. M., Bancks, M. P., Houben, A. J. H. M., Kroon, A. A., Koster, A., Bosma, H., Berendschot, T. T. J. M., de Galan, B. E., & van Sloten, T. T. (2025). Diabetes and incident stroke and mediation by microvascular dysfunction: Pooled analysis of three population-based studies. Diabetes Obesity & Metabolism, 27(4), 2299-2304. Article 16217. https://doi.org/10.1111/dom.16217
- Berends, E., Vangrieken, P., Amiri, N., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., Hermes, D. J. H. P., Wouters, K., van Oostenbrugge, R. J., Schalkwijk, C. G., & Foulquier, S. (2025). Increased Levels of Circulating Methylglyoxal Have No Consequence for Cerebral Microvascular Integrity and Cognitive Function in Young Healthy Mice. Molecular Neurobiology, 62(4), 4190-4202. Article 101148. https://doi.org/10.1007/s12035-024-04552-3
- Heersche, N., Lanser, D. A. C., Muntinghe-Wagenaar, M. B., Mohmaed Ali, M. I., Ulas, E. B., Trooster, T. M. A., de Jonge, E., Oomen-de Hoop, E., Paats, M. S., Bahce, I., Croes, S., Hendriks, L. E. L., van der Wekken, A. J., Dingemans, A.-M. C., Huitema, A. D. R., van Schaik, R. H. N., Mathijssen, R. H. J., & Veerman, G. D. M. (2025). Sex and Common Germline Variants Affect the Toxicity Profile and Pharmacokinetics of Alectinib: A Nationwide Cohort Study in Patients With ALK-Positive NSCLC. Journal of Thoracic Oncology, 20(4), 475-486. https://doi.org/10.1016/j.jtho.2024.11.025
- Tichler, A., Hertroijs, D. F. L., Ruwaard, D., Brouwers, M. C. G. J., & Elissen, A. M. J. (2025). Development of a patient decision aid for type 2 diabetes mellitus: a patient-centered approach. BMC primary care, 26(1), Article 81. https://doi.org/10.1186/s12875-025-02772-7
- Pereboom, J., Meulenbroeks, D., Gerards, S. M. P. L., Eussen, S. J. P. M., Scheepers, H. C. J., Jonkers, D. M. A. E., & Gubbels, J. S. (2025). Mothers adhering to a vegan diet: feeding practices of their young children and underlying determinants - a qualitative exploration. Journal of Nutritional Science, 14, Article e26. https://doi.org/10.1017/jns.2025.14
- Koene, E. J., Buziau, A. M., Cassiman, D., Cox, T. M., Bons, J., Scheijen, J. L. J. M., Schalkwijk, C. G., Meex, S. J., Saxena, A. R., Esler, W. P., Schrauwen-Hinderling, V. B., Schrauwen, P., & Brouwers, M. C. (2025). Safety and efficacy of pharmacological inhibition of ketohexokinase in hereditary fructose intolerance. Journal of Clinical Investigation, 135(6), Article e187376. https://doi.org/10.1172/JCI187376
- Tore, E. C., Adriaans, B. C., Olsen, T., Vinknes, K. J., Kooi, M. E., Elshorbagy, A. K., Bastani, N. E., Dagnelie, P. C., Eussen, S. J. P. M., Gundersen, T. E., Kožich, V., Refsum, H., Retterstøl, K., Stolt, E. T. K., & van Greevenbroek, M. M. J. (2025). Estimated stearoyl-CoA desaturase activity mediates the associations of total cysteine with adiposity: The Maastricht Study. Journal of Clinical Lipidology, 19(2), 348-357. https://doi.org/10.1016/j.jacl.2024.11.005
- Gaartman, A. E., Beuger, B. M., de Ligt, L. A., Veldthuis, M., Matlung, H. L., Meijers, J. C. M., Schalkwijk, C. G., de Heer, K., Heijmans, J., van Zwieten, R., Biemond, B. J., van Bruggen, R., & Nur, E. (2025). Low-dose iron chelation as anti-oxidative therapy in patients with sickle cell disease: A single-centre pilot study. British Journal of Haematology, 206(3), 1010-1013. https://doi.org/10.1111/bjh.19943
- Vangrieken, P., Scheijen, J. L. J. M., Schiffers, P. M. H., van de Waarenburg, M. P. H., Foulquier, S., & Schalkwijk, C. C. G. (2025). Modelling the effects of elevated methylglyoxal levels on vascular and metabolic complications. Scientific Reports, 15(1), Article 6025. https://doi.org/10.1038/s41598-025-90661-5
- Oomens, J. E., Moonen, J. E. F., Vos, S. J. B., Beran, M., Mateus, P., De Deyn, P. P., van der Flier, W. M., Geerlings, M. I., Huisman, M. A., Ikram, M. A., Schram, M. T., Slagboom, P. E., Verschuren, W. M. M., Beekman, M., Bermejo, I., Birhanu, M., Bron, E. E., Dekker, A., Frentz, I., ... Visser, P. J. (2025). Identifying pathways to the prevention of dementia: the Netherlands consortium of dementia cohorts. BMC Neurology, 25(1), Article 59. https://doi.org/10.1186/s12883-024-03995-4
- Beuken, M. J., Kleynen, M., Braun, S., Van Berkel, K., van der Kallen, C., Koster, A., Bosma, H., Berendschot, T. T., Houben, A. J., Dukers-Muijrers, N., van den Bergh, J. P., Kroon, A. A., Kanera, I. M., & Maastricht Study Management (2025). Identification of Clusters in a Population With Obesity Using Machine Learning: Secondary Analysis of The Maastricht Study. JMIR Medical Informatics, 13, Article e64479. https://doi.org/10.2196/64479
- Tokgöz, S., Boss, M., Jansen, T. J., Meijer, R., Frielink, C., van Bon, A. C., Tack, C. J., de Galan, B. E., & Gotthardt, M. (2025). Activation of the HPA axis does not explain non-responsiveness to GLP-1R agonist treatment in individuals with type 2 diabetes. Diabetes, 74(2), 212-222. https://doi.org/10.2337/db24-0463
- Coral, D. E., Smit, F., Farzaneh, A., Gieswinkel, A., Tajes, J. F., Sparsø, T., Delfin, C., Bauvin, P., Wang, K., Temprosa, M., De Cock, D., Blanch, J., Fernández-Real, J. M., Ramos, R., Ikram, M. K., Gomez, M. F., Kavousi, M., Panova-Noeva, M., Wild, P. S., ... Franks, P. W. (2025). Author Correction: Subclassification of obesity for precision prediction of cardiometabolic diseases. Nature Medicine, 31(2). https://doi.org/10.1038/s41591-024-03403-x
- van Oeteren, M. A. J., Simons, N., Simons, P. I. H. G., van de Waarenburg, M. P. H., Kooi, M. E., Feskens, E. J. M., van der Ploeg, E. M. C. L., Van den Eynde, M. D. G., Houben, A. J. H. M., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). Fructose restriction has beneficial effects on adipose tissue distribution but not on serum adipokine levels: Post-hoc analysis of a double-blind randomized controlled trial. Clinical Obesity, 15(1), Article e12714. https://doi.org/10.1111/cob.12714
- Coral, D. E., Smit, F., Farzaneh, A., Gieswinkel, A., Tajes, J. F., Sparsø, T., Delfin, C., Bauvain, P., Wang, K., Temprosa, M., De Cock, D., Blanch, J., Fernández-Real, J. M., Ramos, R., Ikram, M. K., Gomez, M. F., Kavousi, M., Panova-Noeva, M., Wild, P. S., ... Franks, P. W. (2025). Subclassification of obesity for precision prediction of cardiometabolic diseases. Nature Medicine, 31(2), 534-543. https://doi.org/10.1038/s41591-024-03299-7
- Bloch, M. J., Azizi, M., Kirtane, A. J., Mahfoud, F., Sharp, A. S. P., McGuire, M., McClure, C. K., Weber, M., Bae, R., McMeans, A., Goldman, J. A., Jenkins, J. S., Tutor, I., Harrison, M., Penning, A., Tran, A., Bhatia, K., Sobieszczyk, P., Halliday, I., ... de Haan, C. (2025). Changes in blood pressure after crossover to ultrasound renal denervation. Eurointervention, 21(1), 93-95. https://doi.org/10.4244/EIJ-D-24-00321
- Vossen, L. M., Schurgers, L. J., de Haan, C., Kroon, A. A., & de Leeuw, P. W. (2025). Adherence to dietary supplementation with menaquinone-7, a vitamin K2 analogue. Exploration of Medicine, 6, Article 1001321. https://doi.org/10.37349/emed.2025.1001321
- Buziau, A. M., Lefeber, D. J., Cassiman, D., Rubio-Gozalbo, M. E., Kwast, H., Tolan, D. R., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). Aldolase B Deficient Mice Are Characterized by Hepatic Nucleotide Sugar Abnormalities. Journal of Inherited Metabolic Disease, 48(1), Article e12836. https://doi.org/10.1002/jimd.12836
- Appelboom, Y., Groenen, Y., Notten, D., De Bruin, A., Buijs, J., Haak, H. R., Broggreve, H. F., Lambriks, L., & Stassen, P. M. (2025). Experienced cognitive load in the emergency department. A prospective study. PLOS ONE, 20(1), Article e0314052. https://doi.org/10.1371/journal.pone.0314052
- Li-Gao, R., Bot, M., Kurilshikov, A., Willemsen, G., van Greevenbroek, M. M. J., Schram, M. M. T., Stehouwer, C. D. A., Fu, J., Zhernakova, A., Penninx, B. W. J. H., De Geus, E. J. C., Boomsma, D. I., Kupper, N., & BBMRI-NL Metabolomics Consortium (2025). Metabolomics profiling of Type D personality traits. Journal of Psychosomatic Research, 188, Article 111994. https://doi.org/10.1016/j.jpsychores.2024.111994
- Balfoort, B. M., van den Broeck, F., Boon, C. J. F., Brouwers, M. C. G. J., Diederen, R. M. H., Dhillon, P., van Hasselt, P. M., Jaeger, B., Karuntu, J. S., Rennings, A. J. M., van Spronsen, F. J., Timmer, C., Wagenmakers, M. A. E. M., De Zaeytijd, J., Leroy, B. P., Schulze, A., van Karnebeek, C. D., Brands, M. M., & GACR “Bird's Eye View” Consortium (2025). Novel Insights Into Gyrate Atrophy of the Choroid and Retina (GACR): A Cohort Study. Journal of Inherited Metabolic Disease, 48(1), Article e12842. https://doi.org/10.1002/jimd.12842
- Neutel, C. H. G., van der Laan, K. W. F., Wesley, C. D., Krueger, D. N., Pencheva, M. G., Schalkwijk, C. G., De Meyer, G. R. Y., Martinet, W., Delhaas, T., Reesink, K. D., Giudici, A., Guns, P.-J., & Spronck, B. (2025). The MAASWERP Study: An International, Comparative Case Study on Measuring Biomechanics of the Aged Murine Aorta. Pulse, 13(1), 1-10. https://doi.org/10.1159/000542694
- Lips, N., Singh, A., Weir, D., & Karapinar-Carkit, F. (2025). Comparing the performance of multiple trigger tools in identifying medication-related hospital readmissions. Journal of the American Geriatrics Society, 73(1), 162-171. Article 19216. https://doi.org/10.1111/jgs.19216
- Graafsma, J., van de Garde, E. M. W., Derijks, H. J., Hoge, R. H. L., Klopotowska, J. E., Karapinar-Carkit, F., van den Bemt, P. M. L. A., & Dutch CDSS-efficiency study group (2025). Efficiency of computerized clinical decision support systems involving anticoagulants: A flashmob study in Dutch hospital pharmacies. British Journal of Clinical Pharmacology, 91(1), 157-165. Article 16236. https://doi.org/10.1111/bcp.16236
- Dalnoki, L., Hurks, P. P. M., Gubbels, J. S., Eussen, S. J. P. M., Mommers, M., & Thijs, C. (2025). Exploring the Relationship of Dietary Intake With Inattention, Hyperactivity, and Impulsivity, Beyond ADHD. Journal of Attention Disorders, 29(1), 70-79. https://doi.org/10.1177/10870547241293946
- Panagiotou, M., Brigato, L., Streit, V., Hayoz, A., Proennecke, S., Athanasopoulos, S., Olsen, M. T., Den Brok, E. J., Svensson, C. H., Makrilakis, K., Xatzipsalti, M., Vazeou, A., Mertens, P. R., Pedersen-Bjergaard, U., De Galan, B. E., & Mougiakakou, S. (2025). Personalized Insulin Adjustment With Reinforcement Learning: An In-Silico Validation for People with Diabetes on Intensive Insulin Treatment. IEEE Access, 13, 148436-148455. https://doi.org/10.1109/ACCESS.2025.3600738
- 2024
- Wynants, L., Broers, N., Platteel, T., Venekamp, R., Barten, D., Leers, M., Verheij, T., Stassen, P., Cals, J., & de Bont, E. (2024). Development and validation of a risk prediction model for hospital admission in COVID-19 patients presenting to primary care. European Journal of General Practice, 30(1), Article 2339488. https://doi.org/10.1080/13814788.2024.2339488
- Stuijt, C. C. M., Karapinar-carkit, F., van de Steeg-van Gompel, C., van Laar, T., van den Bemt, B. J. F., & Heringa, M. (2024). Feasibility of a Pharmabuddy Care Service for patients with Parkinson's disease. BMC Health Services Research, 24(1), Article 1560. https://doi.org/10.1186/s12913-024-12057-x
- Schuetz, L. T., Duran, G., Baeten, P., Lintsen, D., Hermans, D., Chenine, S., Verreycken, J., Vanmierlo, T., Wouters, K., & Broux, B. (2024). Sex differentially affects pro-inflammatory cell subsets in adipose tissue depots in a diet induced obesity model. Biology of Sex Differences, 15(1), Article 105. https://doi.org/10.1186/s13293-024-00677-1
- Hoope, S. T., Benlamkaddam, M., Koster, E., Duyvendakv, M., Abdullah-Koolmees, H., & Karapinar-Çarkit, F. (2024). De tijdsbelasting en uitvoering van medicatieverificatie voor (poli)klinische patiënten in Nederlandse ziekenhuizen. Pharmaceutisch Weekblad, 159(49), 21-27. https://www.npfo.nl/assets/article/downloads/a1788_28nov2024.pdf
- Mokhtar, S. B. A., Viljoen, J., van der Kallen, C. J. H., Berendschot, T. T. J. M., Dagnelie, P. C., Albers, J. D., Soeterboek, J., Scarpa, F., Colonna, A., van der Heide, F. C. T., van Greevenbroek, M. M. J., Bosm, H., Kroon, A. A., Nuijts, R. M. M. A., Gijs, M., Lakerveld, J., Malik, R. A., Webers, C. A. B., Stehouwer, C. D. A., & Koster, A. (2024). Greater exposure to PM<inf>2.5</inf> and PM<inf>10</inf> was associated with lower corneal nerve measures: the Maastricht study - a cross-sectional study. Environmental Health, 23(1), Article 70. https://doi.org/10.1186/s12940-024-01110-1
- Drenthen, L. C. A., Ajie, M., de Baaij, J. H. F., Tack, C. J., de Galan, B. E., & Stienstra, R. (2024). Magnesium supplementation modulates T-cell function in people with type 2 diabetes and low serum magnesium levels. Journal of Clinical Endocrinology & Metabolism, 109(12), e2240-e2245. Article dgae097. https://doi.org/10.1210/clinem/dgae097
- Lemmens, T. P., Luo, Q., Wielders, S. J. H., Scheijen, J. L. J. M., Al-Nasiry, S., Koenen, R. R., Wenzel, P., & Cosemans, J. M. E. M. (2024). Platelet collagen receptors and their role in modulating platelet adhesion patterns and activation on alternatively processed collagen substrates. Thrombosis Research, 244, Article 109201. https://doi.org/10.1016/j.thromres.2024.109201




