• 2022
    • Konopka, M. J., Kohler, S., Stehouwer, C. D. A., Schaper, N. C., Henry, R. M. A., van der Kallen, C. J. H., Savelberg, H. H. C. M., Eussen, S. J. P. M., Dagniele, P. C., van Dongen, M. C. J. M., Schram, M. T., & Koster, A. (2022). Accelerometer-derived sedentary time and physical activity and the incidence of depressive symptoms - The Maastricht Study. Psychological Medicine, 52(13), 2786-2793. https://doi.org/10.1017/S0033291720004924
    • Spaetgens, B., Brouns, S. H. A., Linkens, A. E. M. J. H., Poeze, M., Ten Broeke, R. H. M., Brüggemann, R. A. G., Sipers, W., Henry, R. M. A., & Hanssen, N. M. J. (2022). Associations between presence of diabetes, mortality and fracture type in individuals with a hip fracture. Diabetes Research and Clinical Practice, 192, Article 110084. https://doi.org/10.1016/j.diabres.2022.110084
    • Córdova, R., Mayén, A.-L., Knaze, V., Aglago, E. K., Schalkwijk, C., Wagner, K.-H., Overvad, K., Tjønneland, A., Kyrø, C., Katzke, V. A., Cornet, C. L., Schulze, M. B., Birukov, A., Palli, D., Grioni, S., Pasanisi, F., Catalano, A., Sandanger, T. M., Gram, I. T., ... Freisling, H. (2022). Dietary intake of advanced glycation endproducts (AGEs) and cancer risk across more than 20 anatomical sites: A multinational cohort study. Cancer Communications, 42, 1041-1045. https://doi.org/10.1002/cac2.12343
    • Top, W. M. C., Lehert, P., Schalkwijk, C. G., Stehouwer, C. D. A., & Kooy, A. (2022). Effect of metformin on arginine and dimethylarginines in patients with advanced type 2 diabetes: A post hoc analysis of a randomized trial. Diabetes Obesity & Metabolism, 24(10), 1983-1988. https://doi.org/10.1111/dom.14784
    • Janssen, L. E. F., Simons, N., Simons, P. I. H. G., Schaper, N. C., Feskens, E. J. M., van der Ploeg, L. M. C., Van den Eynde, M. D. G., Schalkwijk, C. G., Houben, A. J. H. M., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Effects of fructose restriction on blood pressure: Secondary analysis of a double-blind randomized controlled trial. Clinical Nutrition ESPEN, 51, 97-103. https://doi.org/10.1016/j.clnesp.2022.07.009
    • Brouwers, M. C. G. J. (2022). Fructose 1-phosphate, an evolutionary signaling molecule of abundancy. Trends in Endocrinology and Metabolism, 33(10), 680-689. https://doi.org/10.1016/j.tem.2022.07.007
    • Sun, C., van Soest, J., Koster, A., Eussen, S. J. P. M., Schram, M. T., Stehouwer, C. D. A., Dagnelie, P. C., & Dumontier, M. (2022). Studying the association of diabetes and healthcare cost on distributed data from the Maastricht Study and Statistics Netherlands using a privacy-preserving federated learning infrastructure. Journal of Biomedical Informatics, 134. https://doi.org/10.1016/j.jbi.2022.104194
    • Pinxt, C. M. H., Bogie, R. M. M., Hanssen, N. M. J., & Spaetgens, B. (2022). COVID-19: a wake-up call for antibiotic overuse in older patients?QJM: An International Journal of Medicine, 115(9), 637-637. https://doi.org/10.1093/qjmed/hcab234
    • Geraets, A. F. J., Schram, M. T., Jansen, J. F. A., Backes, W. H., Schalkwijk, C. G., Stehouwer, C. D. A., van Boxtel, M. P. J., Eussen, S. J. P. M., Kooman, J. P., Verhey, F. R. J., & Köhler, S. (2022). The cardiometabolic depression subtype and its association with clinical characteristics: The Maastricht Study. Journal of Affective Disorders, 313, 110-117. https://doi.org/10.1016/j.jad.2022.06.045
    • Baylan, U., Korn, A., Emmens, R. W., Schalkwijk, C. G., Niessen, H. W. M., Krijnen, P. A. J., & Simsek, S. (2022). Liraglutide treatment attenuates inflammation markers in the cardiac, cerebral and renal microvasculature in streptozotocin-induced diabetic rats. European Journal of Clinical Investigation, 52(9), Article 13807. https://doi.org/10.1111/eci.13807
    • van Vliet, K., van Ginkel, W. G., Jahja, R., Daly, A., MacDonald, A., Santra, S., De Laet, C., Goyens, P. J., Vara, R., Rahman, Y., Cassiman, D., Eyskens, F., Timmer, C., Mumford, N., Gissen, P., Bierau, J., van Hasselt, P. M., Wilcox, G., Morris, A. A. M., ... van Spronsen, F. J. (2022). Neurocognitive outcome and mental health in children with tyrosinemia type 1 and phenylketonuria: A comparison between two genetic disorders affecting the same metabolic pathway. Journal of Inherited Metabolic Disease, 45(5), 952-962. https://doi.org/10.1002/jimd.12528
    • Koene, E., Schrauwen-Hinderling, V. B., Schrauwen, P., & Brouwers, M. C. G. J. (2022). Novel insights in intestinal and hepatic fructose metabolism: from mice to men. Current Opinion in Clinical Nutrition and Metabolic Care, 25(5), 354-359. https://doi.org/10.1097/MCO.0000000000000853
    • van Dinther, M., Voorter, P. H. M., Schram, M. T., Berendschot, T. T. J. M., Houben, A. J. H. M., Webers, C. A. B., van Oostenbrugge, R. J., Backes, W. H., Staals, J., & Jansen, J. F. A. (2022). Retinal microvascular function is associated with the cerebral microcirculation as determined by intravoxel incoherent motion MRI. Journal of the Neurological Sciences, 440, Article 120359. https://doi.org/10.1016/j.jns.2022.120359
    • Leung, S. S., Borg, D. J., McCarthy, D. A., Boursalian, T. E., Cracraft, J., Zhuang, A., Fotheringham, A. K., Flemming, N., Watkins, T., Miles, J. J., Groop, P.-H., Scheijen, J. L., Schalkwijk, C. G., Steptoe, R. J., Radford, K. J., Knip, M., & Forbes, J. M. (2022). Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells. Diabetes, 71(9), 1994-2008. https://doi.org/10.2337/db22-0177
    • Goossens, P., Lu, C., Cao, J., Gijbels, M. J., Karel, J. M. H., Wijnands, E., Claes, B. S. R., Fazzi, G. E., Hendriks, T. F. E., Wouters, K., Smirnov, E., van Zandvoort, M. J. M., Balluff, B., Cuypers, E., Donners, M. M. P. C., Heeren, R. M. A., & Biessen, E. A. L. (2022). Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context. Cell Metabolism, 34(8), 1214-1225.e6. https://doi.org/10.1016/j.cmet.2022.06.012
    • Zhang, X., Schalkwijk, C. G., & Wouters, K. (2022). Immunometabolism and the modulation of immune responses and host defense: A role for methylglyoxal?Biochimica et Biophysica Acta-Molecular Basis of Disease, 1868(8), Article 166425. https://doi.org/10.1016/j.bbadis.2022.166425
    • Latten, G., Claassen, L., Muris, J., Cals, J., & Stassen, P. (2022). Koorts op de HAP: vitals, beslisregels en niet-pluisgevoel. Huisarts en Wetenschap, 65(8), 21-25. https://doi.org/10.1007/s12445-022-1507-x
    • Barutta, F., Bellini, S., Guarrera, S., Matullo, G., Schalkwijk, C., Stehouwer, C. D., Chaturvedi, N., Soedamah-Muthu, S. S., Durazzo, M., & Gruden, G. (2022). Association of Serum MicroRNA-145-5p Levels with Microvascular Complications of Type 1 Diabetes: the EURODIAB Prospective Complications Study. Diabetes Research and Clinical Practice, 190, Article 109987. https://doi.org/10.1016/j.diabres.2022.109987
    • Haring, M. P. D., Peeks, F., Oosterveer, M. H., Brouwers, M. C. G. J., Hollak, C. E. M., Janssen, M. C. H., Langendonk, J. G., Rennings, A. J. M., Wagenmakers, M. A. E. M., Verkade, H. J., Derks, T. G. J., & de Meijer, V. E. (2022). High childhood serum triglyceride concentrations associate with hepatocellular adenoma development in patients with glycogen storage disease type Ia. JHEP Reports, 4(8), Article 100512. https://doi.org/10.1016/j.jhepr.2022.100512
    • Brouwers, M. C. G. J., Simons, N., Kooi, M. E., de Ritter, R., van Dongen, M. C. J. M., Eussen, S. J. P. M., Bekers, O., Kooman, J., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schram, M. T., Schaper, N. C., Schalkwijk, C. G., & Stehouwer, C. D. A. (2022). Intrahepatic lipid content is independently associated with soluble E-selectin levels: The Maastricht study. Digestive and Liver Disease, 54(8), 1038-1043. https://doi.org/10.1016/j.dld.2022.01.130
    • Wauben, B., van Yperen, N. C., van der Poel, M. W., Köhler, S., van Greevenbroek, M. M., & Schouten, H. C. (2022). Long-term effects after stem cell transplantation identified: design of the MOSA study. Journal of Clinical Epidemiology, 148, 10-16. https://doi.org/10.1016/j.jclinepi.2022.03.012
    • van Dalem, J., Werkman, N. C. C., van den Bergh, J. P., Rossi, B., Viggers, R., Eastell, R., Burden, A. M., Stehouwer, C. D. A., Klungel, O. H., Brouwers, M. C. G. J., & Driessen, J. H. M. (2022). Use of sodium-glucose co-transporter 2 inhibitors, changes in body mass index and risk of fracture: a population-based cohort study. Diabetes Research and Clinical Practice, 190, Article 109993. https://doi.org/10.1016/j.diabres.2022.109993
    • Clemmensen, K. K. B., Koster, A., Nielen, J. T. H., Dagnelie, P. C., Stehouwer, C. D. A., Bosma, H., Wesselius, A., Færch, K., & Eussen, S. J. P. M. (2022). Role of weekday variation on glucose, insulin, and triglyceride: A cross-sectional analysis from The Maastricht Study. Journal of Clinical Endocrinology & Metabolism, 107(8), E3145-E3151. https://doi.org/10.1210/clinem/dgac286
    • Machado-Fragua, M. D., Fayosse, A., Yerramalla, M. S., van Sloten, T. T., Tabak, A. G., Kivimaki, M., Sabia, S., & Singh-Manoux, A. (2022). Association of Metabolic Syndrome With Incident Dementia: Role of Number and Age at Measurement of Components in a 28-Year Follow-up of the Whitehall II Cohort Study. Diabetes Care, 45(9), 2127-2135. https://doi.org/10.2337/dc22-0206
    • Rebelos, E., Daniele, G., Campi, B., Saba, A., Koskensalo, K., Ihalainen, J., Saukko, E., Nuutila, P., Backes, W. H., Jansen, J. F. A., Dagnelie, P. C., Köhler, S., de Galan, B. E., van Sloten, T. T., Stehouwer, C. D. A., & Ferrannini, E. (2022). Circulating N-Acetylaspartate does not track brain NAA concentrations, cognitive function or features of small vessel disease in humans. Scientific Reports, 12(1), Article 11530. https://doi.org/10.1038/s41598-022-15670-0
    • Dimakakos, E., Gomatou, G., Catalano, M., Olinic, D. M., Spyropoulos, A. C., Falanga, A., Maraveyas, A., Liew, A., Schulman, S., Belch, J., Gerotziafas, G., Marschang, P., Cosmi, B., Spaak, J., Syrigos, K., Antic, D., Blinc, A., Boc, V., Boccardo, F., ... CANCER-COVID-19 THROMBOSIS COLLABORATIVE GROUP (2022). Thromboembolic Disease in Patients With Cancer and COVID-19: Risk Factors, Prevention and Practical Thromboprophylaxis Recommendations–State-of-the-Art. Anticancer Research, 42(7), 3261-3274. Article 15815. https://doi.org/10.21873/anticanres.15815
    • Jin, S., Kusters, Y. H. A. M., Houben, A. J. H. M., Plat, J., Joris, P. J., Mensink, R. P., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2022). A randomized diet-induced weight-loss intervention reduces plasma complement C3: Possible implication for endothelial dysfunction. Obesity, 30(7), 1401-1410. https://doi.org/10.1002/oby.23467
    • Ruiz, A., Sanchez, D., Lafuente, A., Ortega, G., Buendia, M., Papasey, J., Jimeno, S. Y., Badia, F. P., Palacio, M. E., Abdelnour, C., Ramirez-Torano, F., Maestu, F., Saez, M. E., Tarraga, L., Dagnelie, P. C., & Boada, M. (2022). Evaluation of the Feasibility, Safety and Efficacy of the Use of Intravenous Infusions of Adenosine Triphosphate (ATP) in People Affected by Moderate to Severe Alzheimer's Disease: A Double-Blind Masked Clinical Trial for Dose Finding. JPAD-Journal of prevention of alzheimers disease, 9(3), 425-434. https://doi.org/10.14283/jpad.2022.38
    • Stassen, P., & Westerman, D. (2022). Novice Doctors in the Emergency Department: A Scoping Review. Cureus Journal of Medical Science, 14(6), Article e26245. https://doi.org/10.7759/cureus.26245
    • Sharma, S., Katz, R., Ginsberg, C., Bullen, A., Vallon, V., Thomson, S., Moe, O. W., Hoofnagle, A. N., de Leeuw, P. W., Kroon, A. A., Houben, A. J. H. M., & Ix, J. H. (2022). Renal Clearance of Fibroblast Growth Factor-23 (FGF23) and its Fragments in Humans. Journal of Bone and Mineral Research, 37(6), 1170-1178. https://doi.org/10.1002/jbmr.4553
    • Simons, P. I. H. G., Valkenburg, O., Telgenkamp, I., van der Waaij, K. M., de Groot, D. M., Veeraiah, P., Bons, J. A. P., Derks, T. G. J., Schalkwijk, C. G., Schrauwen-Hinderling, V. B., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Serum sex hormone-binding globulin levels are reduced and inversely associated with intrahepatic lipid content and saturated fatty acid fraction in adult patients with glycogen storage disease type 1a. Journal of Endocrinological Investigation, 45(6), 1227-1234. https://doi.org/10.1007/s40618-022-01753-2
    • Doola, R., Deane, A. M., Barrett, H. L., Okano, S., Tolcher, D. M., Gregory, K., Coombes, J. S., Schalkwijk, C., Todd, A. S., Forbes, J. M., & Sturgess, D. J. (2022). The impact of a modified carbohydrate formula, and its constituents, on glycaemic control and inflammatory markers: A nested mechanistic sub-study. Journal of Human Nutrition and Dietetics, 35(3), 455-465. https://doi.org/10.1111/jhn.12959
    • Wautrecht, J.-C., Olinic, D.-M., Catalano, M., Baines, C., Belch, J., Blinc, A., Buschmann, I., Celovska, D., Colgan, M.-P., Dimakakos, E., Heiss, C., Kolossvary, E., Kozak, M., Kroon, B., Mazzolai, L., Marakomichelakis, G., Pecsvarady, Z., Pias Canedo, M. A., Quere, I., ... Willfort-Ehringer, A. (2022). UEMS Training Requirements for Angiology/Vascular Medicine: European Standards of Postgraduate Medica 2 Specialist Training (2022 Updated Version). International Angiology, 41(3), 258-274. https://doi.org/10.23736/S0392-9590.22.04893-3
    • Linkens, A. M. A., van Best, N., Niessen, P. M., Wijckmans, N. E. G., de Goei, E. E. C., Scheijen, J. L. J. M., van Dongen, M. C. J. M., van Gool, C. C. J. A. W., de Vos, W. M., Houben, A. J. H. M., Stehouwer, C. D. A., Eussen, S. J. M. P., Penders, J., & Schalkwijk, C. G. (2022). A 4-Week Diet Low or High in Advanced Glycation Endproducts Has Limited Impact on Gut Microbial Composition in Abdominally Obese Individuals: The deAGEing Trial. International journal of molecular sciences, 23(10), Article 5328. https://doi.org/10.3390/ijms23105328
    • Veugen, M. G. J., Onete, V. G., Henry, R. M. A., Brunner-La Rocca, H.-P., Koster, A., Dagnelie, P. C., Schaper, N. C., Sep, S. J. S., van der Kallen, C. J. H., van Boxtel, M. P. J., Reesink, K. D., Schouten, J. S., Savelberg, H. H. C. M., Köhler, S., Verhey, F. R., van den Bergh, J. P. W., Schram, M. T., & Stehouwer, C. D. A. (2022). Health burden in type 2 diabetes and prediabetes in The Maastricht Study. Scientific Reports, 12(1), 1-11. Article 7337. https://doi.org/10.1038/s41598-022-11136-5
    • van Sloten, T. T., Souverein, P. C., Stehouwer, C. DA., & Driessen, J. H. (2022). Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers and risk of depression among older people with hypertension. Journal of Psychopharmacology, 36(5), 594-603. Article 02698811221082470. https://doi.org/10.1177/02698811221082470
    • Buziau, A. M., Eussen, S. J. P. M., Kooi, M. E., van der Kallen, C. J. H., van Dongen, M. C. J. M., Schaper, N. C., Henry, R. M. A., Schram, M. T., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Bekers, O., Meex, S. J. R., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Fructose Intake From Fruit Juice and Sugar-Sweetened Beverages Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study. Diabetes Care, 45(5), 1116-1123. https://doi.org/10.2337/dc21-2123
    • Deraz, O., Range, H., Boutouyrie, P., Chatzopoulou, E., Asselin, A., Guibout, C., Van Sloten, T., Bougouin, W., Andrieu, M., Vedie, B., Thomas, F., Danchin, N., Jouven, X., Bouchard, P., & Empana, J. P. (2022). Oral Condition and Incident Coronary Heart Disease: A Clustering Analysis. Journal of Dental Research, 101(5), 526-533. Article 00220345211052507. https://doi.org/10.1177/00220345211052507
    • Vandercappellen, E. J., Koster, A., Savelberg, H. H. C. M., Eussen, S. J. P. M., Dagnelie, P. C., Schaper, N. C., Schram, M. T., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Wesselius, A., Schalkwijk, C. G., Kroon, A. A., Henry, R. M. A., & Stehouwer, C. D. A. (2022). Sedentary behaviour and physical activity are associated with biomarkers of endothelial dysfunction and low-grade inflammation-relevance for (pre)diabetes: The Maastricht Study. Diabetologia, 65(5), 777-789. https://doi.org/10.1007/s00125-022-05651-3
    • Climie, R. E., Tafflet, M., van Sloten, T., de Lauzon-Guillain, B., Bernard, J. Y., Dargent-Molina, P., Plancoulaine, S., Lioret, S., Jouven, X., Charles, M.-A., Heude, B., & Empana, J.-P. (2022). Cardiovascular Health at Age 5 Years: Distribution, Determinants, and Association With Neurodevelopment. Frontiers in pediatrics, 10, Article 827525. https://doi.org/10.3389/fped.2022.827525
    • Zeijen, V. J. M., Lafeber, M., Versmissen, J., Kroon, A. A., Boersma, E., & Daemen, J. (2022). Adequacy of blood pressure control in high-risk hypertensive patients: The DEGREE study. International Journal of Cardiology, 352, 137-143. https://doi.org/10.1016/j.ijcard.2022.02.014
    • Ottaviani, L., Pinto, V. S., Knoops, K., Wouters, K., Martins, P. A. D., & Abreu, R. (2022). Cre/Lox-Assisted Tracking Of Cardiac Intercellular Communication. Tissue Engineering, 28, S339-S340.
    • Mashnafi, S., Plat, J., Mensink, R. P., Joris, P. J., Kusters, Y. H. A. M., Houben, A. J. H. M., Stehouwer, C. D. A., Schalkwijk, C. G., & Baumgartner, S. (2022). Effects of Diet-Induced Weight Loss on Plasma Markers for Cholesterol Absorption and Synthesis: Secondary Analysis of a Randomized Trial in Abdominally Obese Men. Nutrients, 14(8), Article 1546. https://doi.org/10.3390/nu14081546
    • Simons, P. I. H. G., Cornelissen, M. E. B., Valkenburg, O., Onland-Moret, N. C., van der Schouw, Y. T., Stehouwer, C. D. A., Burgess, S., & Brouwers, M. C. G. J. (2022). Causal relationship between polycystic ovary syndrome and coronary artery disease: A Mendelian randomisation study. Clinical Endocrinology, 96(4), 599-604. https://doi.org/10.1111/cen.14593
    • Gennip, A. C. E., Sedaghat, S., Carnethon, M. R., Allen, N. B., Klein, B. E. K., Cotch, M. F., Chirinos, D. A., Stehouwer, C. D. A., & van Sloten, T. T. (2022). Retinal Microvascular Caliber and Incident Depressive Symptoms: The Multi-Ethnic Study of Atherosclerosis. American Journal of Epidemiology, 191(5), 843-855. https://doi.org/10.1093/aje/kwab255
    • Linkens, A. M. A., Houben, A. J., Niessen, P. M., Wijckmans, N., de Goei, E., Van den Eynde, M. D. G., Scheijen, J. L. J. M., Waarenburg, M., Mari, A., Berendschot, T. T. J. M., Streese, L., Hanssen, H., van Dongen, M. C. J. M., van Gool, C., Stehouwer, C. D. A., Eussen, S. J. P. M., & Schalkwijk, C. (2022). A 4-week high-AGE diet does not impair glucose metabolism and vascular function in obese individuals. JCI INSIGHT, 7(6), Article 156950. https://doi.org/10.1172/jci.insight.156950
    • Hop, P. J., Zwamborn, R. A. J., Hannon, E., Shireby, G. L., Nabais, M. F., Walker, E. M., van Rheenen, W., van Vugt, J. J. F. A., Dekker, A. M., Westeneng, H. J., Tazelaar, G. H. P., van Eijk, K. R., Moisse, M., Baird, D., Al Khleifat, A., Iacoangeli, A., Ticozzi, N., Ratti, A., Cooper-Knock, J., ... Brain MEND Consortium (2022). Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science Translational Medicine, 14(633), Article eabj0264. https://doi.org/10.1126/scitranslmed.abj0264
    • van Hulten, V., Sarodnik, C., Driessen, J. H. M., Schaper, N. C., Geusens, P. P. M. M., Webers, C. A. B., Dinant, G.-J., Ottenheijm, R. P. G., Rasmussen, N. H., Viggers, R., Stehouwer, C. D. A., van der Kallen, C. J. H., Schram, M. T., Bours, S. P. G., Dagnelie, P. C., & van den Bergh, J. P. (2022). Prevalent Morphometrically Assessed Vertebral Fractures in Individuals With Type 2 Diabetes, Prediabetes and Normal Glucose Metabolism: The Maastricht Study. Frontiers in Endocrinology, 13, Article 832977. https://doi.org/10.3389/fendo.2022.832977
    • Wu, L., Baylan, U., van der Leeden, B., Schurink, B., Roos, E., Schalkwijk, C. G., Bugiani, M., van der Valk, P., van Rossum, A. C., Zeerleder, S. S., Heunks, L. M. A., Boon, R. A., de Boer, O. J., van der Wal, A. C., Niessen, H. W. M., & Krijnen, P. A. J. (2022). Cardiac inflammation and microvascular procoagulant changes are decreased in second wave compared to first wave deceased COVID-19 patients. International Journal of Cardiology, 349, 157-165. https://doi.org/10.1016/j.ijcard.2021.11.079