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Brouwers, M. C. G. J. (2021). When to Consider an Inborn Error of Metabolism in Adults?Journal of Endocrinology and Metabolism, 11(3-4), 65-68. https://doi.org/10.14740/jem750

Veugen, M. G. J., Linssen, P. B. C., Henry, R. M. A., Koster, A., Kroon, A. A., Stehouwer, C. D. A., & Brunner-La Rocca, H.-P. (2021). Measures of Left Ventricular Diastolic Function and Cardiorespiratory Fitness According to Glucose Metabolism Status: The Maastricht Study. Journal of the American Heart Association, 10(13), Article 020387. https://doi.org/10.1161/jaha.120.020387

Monereo-Sanchez, J., Schram, M. T., Frei, O., O'Connell, K., Shadrin, A. A., Smeland, O. B., Westlye, L. T., Andreassen, O. A., Kaufmann, T., Linden, D. E. J., & van der Meer, D. (2021). Genetic Overlap Between Alzheimer's Disease and Depression Mapped Onto the Brain. Frontiers in Neuroscience, 15, Article 653130. https://doi.org/10.3389/fnins.2021.653130

Linkens, A. M. A., Eussen, S. J. M. P., Houben, A. J. H. M., Kroon, A. A., Schram, M. T., Reesink, K. D., Dagnelie, P. C., Henry, R. M. A., van Greevenbroek, M., Wesselius, A., Stehouwer, C. D. A., & Schalkwijk, C. G. (2021). Habitual Intake of Dietary Advanced Glycation End Products Is Not Associated with Arterial Stiffness of the Aorta and Carotid Artery in Adults: The Maastricht Study. Journal of Nutrition, 151(7), 1886-1893. https://doi.org/10.1093/jn/nxab097

Simons, P. I. H. G., Valkenburg, O., Telgenkamp, I., van der Waaij, K. M., de Groot, D. M., Veeraiah, P., Bons, J. A. P., Taskinen, M. R., Boren, J., Schrauwen, P., Rutten, J. H. W., Cassiman, D., Schalkwijk, C. G., Stehouwer, C. D. A., Schrauwen-Hinderling, V. B., Hodson, L., & Brouwers, M. C. G. J. (2021). Relationship between de novo lipogenesis and serum sex hormone binding globulin in humans. Clinical Endocrinology, 95(1), 101-106. https://doi.org/10.1111/cen.14459

Driessen, R. G. H., Kiers, D., Schalkwijk, C. G., Scheijen, J. L. J. M., Gerretsen, J., Pickkers, P., van de Poll, M. C. G., van der Horst, I. C. C., Bergmans, D. C. J. J., Kox, M., & van Bussel, B. C. T. (2021). Systemic inflammation down-regulates glyoxalase-1 expression: an experimental study in healthy males. Bioscience Reports, 41(7), Article BSR20210954. https://doi.org/10.1042/BSR20210954

Van den Eynde, M. D. G., Scheijen, J. L. J. M., Stehouwer, C. D. A., Miyata, T., & Schalkwijk, C. G. (2021). Quantification of the B6 vitamers in human plasma and urine in a study with pyridoxamine as an oral supplement; pyridoxamine as an alternative for pyridoxine. Clinical Nutrition, 40(7), 4624-4632. https://doi.org/10.1016/j.clnu.2021.05.028

Borg, D. J., Faridi, P., Giam, K. L., Reeves, P., Fotheringham, A. K., McCarthy, D. A., Leung, S., Ward, M. S., Harcourt, B. E., Ayala, R., Scheijen, J. L., Briskey, D., Dudek, N. L., Schalkwijk, C. G., Steptoe, R., Purcell, A. W., & Forbes, J. M. (2021). Short Duration Alagebrium Chloride Therapy Prediabetes Does Not Inhibit Progression to Autoimmune Diabetes in an Experimental Model. Metabolites, 11(7), Article 426. https://doi.org/10.3390/metabo11070426

Simons, P. I. H. G., Valkenburg, O., Bons, J. A. P., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2021). The relationships of sex hormone-binding globulin, total testosterone, androstenedione and free testosterone with metabolic and reproductive features of polycystic ovary syndrome. Endocrinology, Diabetes & Metabolism, 4(3), Article 00267. https://doi.org/10.1002/edm2.267

Azizi, M., Sanghvi, K., Saxena, M., Gosse, P., Reilly, J. P., Levy, T., Rump, L. C., Persu, A., Basile, J., Bloch, M. J., Daemen, J., Lobo, M. D., Mahfoud, F., Schmieder, R. E., Sharp, A. S. P., Weber, M. A., Sapoval, M., Fong, P., Pathak, A., ... de Haan, C. (2021). Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial. Lancet, 397(10293), 2476-2486. https://doi.org/10.1016/s0140-6736(21)00788-1

van Doorn, W. P. T. M., Foreman, Y. D., Schaper, N. C., Savelberg, H. H. C. M., Koster, A., van der Kallen, C. J. H., Wesselius, A., Schram, M. T., Henry, R. M. A., Dagnelie, P. C., de Galan, B. E., Bekers, O., Stehouwer, C. D. A., Meex, S. J. R., & Brouwers, M. C. G. J. (2021). Machine learning-based glucose prediction with use of continuous glucose and physical activity monitoring data: The Maastricht Study. PLOS ONE, 16(6), Article 0253125. https://doi.org/10.1371/journal.pone.0253125

Timmons, J. G., Greenlaw, N., Boyle, J. G., Chaturvedi, N., Ford, I., Brouwers, M. C. G. J., Tillin, T., Hramiak, I., Hughes, A. D., Jenkins, A. J., Klein, B. E. K., Klein, R., Ooi, T. C., Rossing, P., Stehouwer, C. D. A., Sattar, N., Colhoun, H. M., Petrie, J. R., & REMOVAL Study Grp (2021). Metformin and carotid intima-media thickness in never-smokers with type 1 diabetes: The REMOVAL trial. Diabetes Obesity & Metabolism, 23(6), 1371-1378. https://doi.org/10.1111/dom.14350

Mastrocola, R., Dal Bello, F., Cento, A. S., Gaens, K., Collotta, D., Aragno, M., Medana, C., Collino, M., Wouters, K., & Schalkwijk, C. G. (2021). Altered hepatic sphingolipid metabolism in insulin resistant mice: Role of advanced glycation endproducts. Free Radical Biology and Medicine, 169, 425-435. https://doi.org/10.1016/j.freeradbiomed.2021.04.028

Dalem, J. V., Brouwers, M. C. G. J., Burden, A. M., Stehouwer, C. D. A., Klungel, O. H., Vries, F. D., & Driessen, J. H. M. (2021). Determinants of treatment modification before and after implementation of the updated 2015 NICE guideline on type 2 diabetes: A retrospective cohort study. Diabetes Research and Clinical Practice, 176, Article 108828. https://doi.org/10.1016/j.diabres.2021.108828

Bosveld, M. H., van Doorn, D. P. C., Stassen, P. M., Westerman, D., Bergmans, D. C. J. J., van der Horst, I. C. C., & van Mook, W. N. K. A. (2021). Lessons learned: Contribution to healthcare by medical students during COVID-19. Journal of Critical Care, 63, 113-116. https://doi.org/10.1016/j.jcrc.2020.09.015

Lindekilde, N., Rutters, F., Henriksen, J. E., Lasgaard, M., Schram, M. T., Rubin, K. H., Kivimaki, M., Nefs, G., & Pouwer, F. (2021). Psychiatric disorders as risk factors for type 2 diabetes: An umbrella review of systematic reviews with and without meta-analyses. Diabetes Research and Clinical Practice, 176, Article 108855. https://doi.org/10.1016/j.diabres.2021.108855

Kalafati, M., Lenz, M., Ertaylan, G., Arts, I. C. W., Evelo, C. T., van Greevenbroek, M. M. J., Blaak, E. E., Adriaens, M., & Kutmon, M. (2021). Assessing the Contribution of Relative Macrophage Frequencies to Subcutaneous Adipose Tissue. Frontiers in nutrition, 8, Article 675935. https://doi.org/10.3389/fnut.2021.675935

Maasen, K., Scheijen, J. L. J. M., Opperhuizen, A., Stehouwer, C. D. A., Van Greevenbroek, M. M., & Schalkwijk, C. G. (2021). Corrigendum to “Quantification of dicarbonyl compounds in commonly consumed foods and drinks; presentation of a food composition database for dicarbonyls” [Food Chemistry, 339 (2020) 128063]. Food Chemistry, 344, Article 128578. https://doi.org/10.1016/j.foodchem.2020.128578

de Ritter, R., Sep, S. J. S., van der Kallen, C. J. H., van Greevenbroek, M. M. J., de Jong, M., Vos, R. C., Bots, M. L., Reulen, J. P. H., Houben, A. J. H. M., Webers, C. A. B., Berendschot, T. T. J. M., Dagnelie, P. C., Eussen, S. J. P. M., Schram, M. T., Koster, A., Peters, S. A. E., & Stehouwer, C. D. A. (2021). Sex differences in the association of prediabetes and type 2 diabetes with microvascular complications and function: The Maastricht Study. Cardiovascular Diabetology, 20(1), Article 102. https://doi.org/10.1186/s12933-021-01290-x

Kožich, V., Sokolová, J., Morris, A. A. M., Pavlíková, M., Gleich, F., Kölker, S., Krijt, J., Dionisi-Vici, C., Baumgartner, M. R., Blom, H. J., Huemer, M., Aldámiz-Echevarría, L., Arantes, R. R., Arrieta, F., Blasco-Alonso, J., Brouwers, M., Brunner-Krainz, M., Bueno, M., Peláez, R. B., ... E-HOD consortium (2021). Cystathionine β-synthase deficiency in the E-HOD registry-part I: pyridoxine responsiveness as a determinant of biochemical and clinical phenotype at diagnosis. Journal of Inherited Metabolic Disease, 44(3), 677-692. https://doi.org/10.1002/jimd.12338

Molema, F., Haijes, H. A., Janssen, M. C., Bosch, A. M., van Spronsen, F. J., Mulder, M. F., Verhoeven-Duif, N. M., Jans, J. J. M., van der Ploeg, A. T., Wagenmakers, M. A., Rubio-Gozalbo, M. E., Brouwers, M. C. G. J., de Vries, M. C., Fuchs, S., Langendonk, J. G., Rizopoulos, D., van Hasselt, P. M., & Williams, M. (2021). High protein prescription in methylmalonic and propionic acidemia patients and its negative association with long-term outcome. Clinical Nutrition, 40(5), 3622-3630. https://doi.org/10.1016/j.clnu.2020.12.027

Cobussen, M., Haeseker, M. B., Stoffers, J., Wanrooij, V. H. M., Savelkoul, P. H. M., & Stassen, P. M. (2021). Renal safety of a single dose of gentamicin in patients with sepsis in the emergency department. Clinical Microbiology and Infection, 27(5), 717-723. https://doi.org/10.1016/j.cmi.2020.06.030

Van den Eynde, M. D. G., Kusters, Y. H. A. M., Houben, A. J. H. M., Scheijen, J. L. J. M., van Duynhoven, J., Fazelzadeh, P., Joris, P. J., Plat, J., Mensink, R. P., Hanssen, N. M. J., Stehouwer, C. D. A., & Schalkwijk, C. G. (2021). Diet-induced weight loss reduces postprandial dicarbonyl stress in abdominally obese men: Secondary analysis of a randomized controlled trial. Clinical Nutrition, 40(5), 2654-2662. https://doi.org/10.1016/j.clnu.2021.03.042

Aglago, E. K., Schalkwijk, C. G., Freisling, H., Fedirko, V., Hughes, D. J., Jiao, L., Dahm, C. C., Olsen, A., Tjonneland, A., Katzke, V., Johnson, T., Schulze, M. B., Aleksandrova, K., Masala, G., Sieri, S., Simeon, V., Tumino, R., Macciotta, A., Bueno-de-Mesquita, B., ... Jenab, M. (2021). Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study. Carcinogenesis, 42(5), 705-713. https://doi.org/10.1093/carcin/bgab026

van den Kerkhof, M., Voorter, P. H. M., Canjels, L. P. W., de Jong, J. J. A., van Oostenbrugge, R. J., Kroon, A. A., Jansen, J. F. A., & Backes, W. H. (2021). Time-efficient measurement of subtle blood-brain barrier leakage using a T-1 mapping MRI protocol at 7 T. Magnetic Resonance in Medicine, 85(5), 2761-2770. https://doi.org/10.1002/mrm.28629

Amidei, C. B., Fayosse, A., Dumurgier, J., Machado-Fragua, M. D., Tabak, A. G., van Sloten, T., Kivimaki, M., Dugravot, A., Sabia, S., & Singh-Manoux, A. (2021). Association Between Age at Diabetes Onset and Subsequent Risk of Dementia. JAMA-Journal of the American Medical Association, 325(16), 1640-1649. https://doi.org/10.1001/jama.2021.4001

Chatterjee, A., Wu, G., Primakov, S., Oberije, C., Woodruff, H., Kubben, P., Henry, R., Aries, M. J. H., Beudel, M., Noordzij, P. G., Dormans, T., van den Oever, N. C. G., van den Bergh, J. P., Wyers, C. E., Simsek, S., Douma, R., Reidinga, A. C., de Kruif, M. D., Guiot, J., ... Lambin, P. (2021). Can predicting COVID-19 mortality in a European cohort using only demographic and comorbidity data surpass age-based prediction: An externally validated study. PLOS ONE, 16(4), Article e0249920. https://doi.org/10.1371/journal.pone.0249920

Stolt, E., Olsen, T., Elshorbagy, A., Kozich, V., van Greevenbroek, M., Ovrebo, B., Thoresen, M., Refsum, H., Retterstol, K., & Vinknes, K. J. (2021). Sulfur amino acid restriction, energy metabolism and obesity: a study protocol of an 8-week randomized controlled dietary intervention with whole foods and amino acid supplements. Journal of Translational Medicine, 19(1), Article 153. https://doi.org/10.1186/s12967-021-02824-3

Top, W. M. C., Lehert, P., Schalkwijk, C. G., Stehouwer, C. D. A., & Kooy, A. (2021). Metformin and N-terminal pro B-type natriuretic peptide in type 2 diabetes patients, a post-hoc analysis of a randomized controlled trial. PLOS ONE, 16(4), Article 0247939. https://doi.org/10.1371/journal.pone.0247939

van Oort, S., Rutters, F., Warle-van Herwaarden, M. F., Schram, M. T., Stehouwer, C. D., Tack, C. J., Abbink, E. J., Wolffenbuttel, B. H., van der Klauw, M. M., DeVries, J. H., Siegelaar, S. E., Sijbrands, E. J., Ozcan, B., de Valk, H. W., Silvius, B., Schroijen, M. A., Jazet, I. M., van Ballegooijen, A. J., Beulens, J. W. J., ... Kramers, C. (2021). Characteristics associated with polypharmacy in people with type 2 diabetes: the Dutch Diabetes Pearl cohort. Diabetic Medicine, 38(4), Article 14406. https://doi.org/10.1111/dme.14406

Houben, A. J. H. M., & Stehouwer, C. D. A. (2021). Microvascular dysfunction: Determinants and treatment, with a focus on hyperglycemia. Endocrine and Metabolic Science, 2, Article 100073. https://doi.org/10.1016/j.endmts.2020.100073

Zhou, T. L., Kroon, A. A., Henry, R. M. A., Koster, A., Dagnelie, P. C., Bosma, H., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schalkwijk, C. G., Wesselius, A., Reesink, K. D., Köhler, S., Schram, M. T., Stehouwer, C. D. A., & van Sloten, T. T. (2021). Exercise SBP response and incident depressive symptoms: The Maastricht Study. Journal of Hypertension, 39(3), 494-502. https://doi.org/10.1097/HJH.0000000000002657

Maasen, K., Scheijen, J. L. J. M., Opperhuizen, A., Stehouwer, C. D. A., Van Greevenbroek, M. M., & Schalkwijk, C. G. (2021). Quantification of dicarbonyl compounds in commonly consumed foods and drinks; presentation of a food composition database for dicarbonyls. Food Chemistry, 339, Article 128063. https://doi.org/10.1016/j.foodchem.2020.128063

Pappaccogli, M., Di Monaco, S., Warchol-Celinska, E., Lorthioir, A., Amar, L., Aparicio, L. S., Beauloye, C., Bruno, R. M., Chenu, P., de Leeuw, P., De Backer, T., Delmotte, P., Dika, Z., Gordin, D., Heuten, H., Iwashima, Y., Krzesinski, J. M., Kroon, A. A., Mazzolai, L., ... Working Group ‘Hypertension and the Kidney’ of the European Society of Hypertension (ESH) (2021). The European/International Fibromuscular Dysplasia Registry and Initiative (FEIRI)-clinical phenotypes and their predictors based on a cohort of 1000 patients. Cardiovascular Research, 117(3), 950-959. https://doi.org/10.1093/cvr/cvaa102

Lee, M. K. S., Kraakman, M. J., Dragoljevic, D., Hanssen, N. M. J., Flynn, M. C., Al-Sharea, A., Sreejit, G., Bertuzzo-Veiga, C., Cooney, O. D., Baig, F., Morriss, E., Cooper, M. E., Josefsson, E. C., Kile, B. T., Nagareddy, P. R., & Murphy, A. J. (2021). Apoptotic Ablation of Platelets Reduces Atherosclerosis in Mice With Diabetes. Arteriosclerosis Thrombosis and Vascular Biology, 41(3), 1167-1178. https://doi.org/10.1161/ATVBAHA.120.315369

Gianfredi, V., Koster, A., Odone, A., Amerio, A., Signorelli, C., Schaper, N. C., Bosma, H., Köhler, S., Dagnelie, P. C., Stehouwer, C. D. A., Schram, M. T., van Dongen, M. C. J. M., & Eussen, S. J. P. M. (2021). Associations of Dietary Patterns with Incident Depression: The Maastricht Study. Nutrients, 13(3), Article 1034. https://doi.org/10.3390/nu13031034

Hulman, A., Foreman, Y. D., Brouwers, M. C. G. J., Kroon, A. A., Reesink, K. D., Dagnelie, P. C., van der Kallen, C. J. H., van Greevenbroek, M. M. J., Faerch, K., Vistisen, D., Jorgensen, M. E., Stehouwer, C. D. A., & Witte, D. R. (2021). Towards precision medicine in diabetes? A critical review of glucotypes. Plos Biology, 19(3), Article 3000890. https://doi.org/10.1371/journal.pbio.3000890

Crivelli, S. M., Luo, Q., Stevens, J. A. A., Giovagnoni, C., van Kruining, D., Bode, G., den Hoedt, S., Hobo, B., Scheithauer, A. L., Walter, J., Mulder, M. T., Exley, C., Mold, M., Mielke, M. M., De Vries, H. E., Wouters, K., van den Hove, D. L. A., Berkes, D., Ledesma, M. D., ... Martinez-Martinez, P. (2021). CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer’s disease. Alzheimer's Research & Therapy, 13(1), Article 45. https://doi.org/10.1186/s13195-021-00780-0

Schalekamp, S., Bleeker-Rovers, C. P., Beenen, L. F. M., van Ufford, H. M. E. Q., Gietema, H. A., Stoger, J. L., Harris, V., Reijers, M. H. E., Rahamat-Langendoen, J., Korevaar, D. A., Smits, L. P., Korteweg, C., Vellinga, T. F. D. V., Vermaat, M., Stassen, P. M., Scheper, H., Wijnakker, R., Borm, F. J., Dofferhoff, A. S. M., & Prokop, M. M. (2021). Chest CT in the Emergency Department for Diagnosis of COVID-19 Pneumonia: Dutch Experience. Radiology, 298(2), E98-E106. https://doi.org/10.1148/radiol.2020203465

Simons, N., Veeraiah, P., Simons, P. I. H. G., Schaper, N. C., Kooi, M. E., Schrauwen-Hinderling, V. B., Feskens, E. J. M., van der Ploeg, E. M. C., Van den Eynde, M. D. G., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2021). Effects of fructose restriction on liver steatosis (FRUITLESS); a double-blind randomized controlled trial. American Journal of Clinical Nutrition, 113(2), 391-400. https://doi.org/10.1093/ajcn/nqaa332

Vergoossen, L. W. M., Jansen, J. F. A., van Sloten, T. T., Stehouwer, C. D. A., Schaper, N. C., Wesselius, A., Dagnelie, P. C., Köhler, S., van Boxtel, M. P. J., Kroon, A. A., de Jong, J. J. A., Schram, M. T., & Backes, W. H. (2021). Interplay of White Matter Hyperintensities, Cerebral Networks, and Cognitive Function in an Adult Population: Diffusion-Tensor Imaging in the Maastricht Study. Radiology, 298(2), 384-392. https://doi.org/10.1148/radiol.2021202634

Maasen, K., Hanssen, N. M. J., van der Kallen, C. J. H., Stehouwer, C. D. A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2021). Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study. Antioxidants, 10(2), Article 219. https://doi.org/10.3390/antiox10020219

Alnazer, R. M., Veldhuizen, G. P., Kroon, A. A., & de Leeuw, P. W. (2021). The effect of medication on the aldosterone-to-renin ratio. A critical review of the literature. Journal of Clinical Hypertension, 23(2), 208-214. https://doi.org/10.1111/jch.14173

Vergoossen, L. W. M., Jansen, J. F. A., de Jong, J. J. A., Stehouwer, C. D. A., Schaper, N. C., Savelberg, H. H. C. M., Koster, A., Backes, W. H., & Schram, M. T. (2021). Association of physical activity and sedentary time with structural brain networks-The Maastricht Study. Geroscience, 43(1), 239-252. https://doi.org/10.1007/s11357-020-00276-z

Veldhuizen, G. P., Alnazer, R. M., Kroon, A. A., & de Leeuw, P. W. (2021). Confounders of the aldosterone-to-renin ratio when used as a screening test in hypertensive patients: A critical analysis of the literature. Journal of Clinical Hypertension, 23(2), 201-207. https://doi.org/10.1111/jch.14117

Hanssen, N. M. J., Scheijen, J. L. J. M., Houben, A. J. H. M., van de Waarenburg, M., Berendschot, T. T. J. M., Webers, C. A. B., Reesink, K. D., van Greevenbroek, M. M. J., van der Kallen, C., Schaper, N. C., Schram, M. T., Henry, R. M. A., Stehouwer, C. D. A., & Schalkwijk, C. G. (2021). Fasting and post-oral-glucose-load levels of methylglyoxal are associated with microvascular, but not macrovascular, disease in individuals with and without (pre)diabetes: The Maastricht Study. Diabetes & Metabolism, 47(1), Article 101148. https://doi.org/10.1016/j.diabet.2020.02.002

Swiatkiewicz, I., Mila-Kierzenkowska, C., Wozniak, A., Szewczyk-Golec, K., Nuszkiewicz, J., Wroblewska, J., Rajewski, P., Eussen, S. J. P. M., Faerch, K., Manoogian, E. N. C., Panda, S., & Taub, P. R. (2021). Pilot Clinical Trial of Time-Restricted Eating in Patients with Metabolic Syndrome. Nutrients, 13(2), Article 346. https://doi.org/10.3390/nu13020346

van Dam, P. M. E. L., Zelis, N., Stassen, P., van Twist, D. J. L., De Leeuw, P. W., van Kuijk, S., & Buijs, J. (2021). Validating the RISE UP score for predicting prognosis in patients with COVID-19 in the emergency department: a retrospective study. BMJ Open, 11(2), Article e045141. https://doi.org/10.1136/bmjopen-2020-045141

van der Bruggen, M. M., Reesink, K. D., Spronck, P. J. M., Bitsch, N., Hameleers, J., Megens, R. T. A., Schalkwijk, C. G., Delhaas, T., & Spronck, B. (2021). An integrated set-up for ex vivo characterisation of biaxial murine artery biomechanics under pulsatile conditions. Scientific Reports, 11(1), Article 2671. https://doi.org/10.1038/s41598-021-81151-5