• 2024
    • Jooss, N. J., Diender, M. G., Fernandez, D. I., Huang, J., Heubel-Moenen, F. C. J., van der Veer, A., Kuijpers, M. J. E., Poulter, N. S., Henskens, Y. M. C., te Loo, M., & Heemskerk, J. W. M. (2024). Restraining of glycoprotein VI- and integrin a2ß1-dependent thrombus formation by platelet PECAM1. Cellular and Molecular Life Sciences, 81(1), Article 44. https://doi.org/10.1007/s00018-023-05058-2
    • Meier, R. T., Porcelijn, L., Hofstede-van Egmond, S., Henskens, Y. M. C., Coutinho, J. M., Kruip, M. J. H. A., Stroobants, A. K., Zwaginga, J. J., van der Bom, J. G., van der Schoot, C. E., de Haas, M., & Kapur, R. (2024). Laboratory approach for vaccine-induced thrombotic thrombocytopenia diagnosis in the Netherlands. Vox sanguinis. Advance online publication. https://doi.org/10.1111/vox.13633
    • Willems, R. A. L., Konings, J., Huskens, D., Middelveld, H., Pepels-Aarts, N., Verbeet, L., de Groot, P. G., Heemskerk, J. W. M., Ten Cate, H., de Vos-Geelen, J., de Laat, B., & Roest, M. (2024). Altered whole blood thrombin generation and hyperresponsive platelets in patients with pancreatic cancer. Journal of Thrombosis and Haemostasis, 22(4), 1132-1144. https://doi.org/10.1016/j.jtha.2023.12.037
    • van Voorst, H., Hoving, J. W., Koopman, M. S., Daems, J. D., Peerlings, D., Buskens, E., Lingsma, H. F., Beenen, L. F. M., de Jong, H. W. A. M., Berkhemer, O. A., van Zwam, W. H., Roos, Y. B. W. E. M., van Walderveen, M. A. A., van den Wijngaard, I., Dippel, D. W. J., Yoo, A. J., Campbell, B. C. V., Kunz, W. G., Emmer, B. J., ... MR CLEAN Registry Investigators (2024). Cost-effectiveness of CT perfusion for the detection of large vessel occlusion acute ischemic stroke followed by endovascular treatment: a model-based health economic evaluation study. European Radiology, 34(4), 2152-2167. https://doi.org/10.1007/s00330-023-10119-y
    • Ceulemans, A., Spronk, H. M. H., Ten Cate, H., van Zwam, W. H., van Oostenbrugge, R. J., & Nagy, M. (2024). Current and potentially novel antithrombotic treatment in acute ischemic stroke. Thrombosis Research, 236, 74-84. https://doi.org/10.1016/j.thromres.2024.02.009
    • Luu, I. H. Y., Mostard, G. J. M., van Mil, D., van Berlo, M. H. W., Lobbes, M. B. I., Külcü, K., Cate, H. T., Peeters, J., Palmen, J., Buijs, J., Jie, K. S. G., van Kampen, R. J. W., & van Twist, D. J. L. (2024). Deferring diagnostic evaluation for suspected deep venous thrombosis using a single dose of anticoagulant: Real-world data from a regionwide care pathway. European journal of internal medicine, 122, 54-60. https://doi.org/10.1016/j.ejim.2023.12.021
    • Ten Cate-Hoek, A., & Ten Cate, H. (2024). Stressful experiences and venous thromboembolism. European journal of internal medicine, 122, 38-39. https://doi.org/10.1016/j.ejim.2024.01.014
    • de Jong, M. J., Saadan, H., Hellenbrand, D. L. S., Ten Cate, H., Spaetgens, B., Brüggemann, R. A. G., van Kuijk, S. M. J., Winckers, K., Henskens, Y. M. C., & Magdelijns, F. J. H. (2024). The DOAC-FRAIL study, evaluation of direct oral anticoagulant-levels in acutely admitted frail older patients: An exploratory study. Journal of the American Geriatrics Society. Advance online publication. https://doi.org/10.1111/jgs.18894
    • Iding, A. F. J., Alkarithi, G., Ten Cate, H., Ariëns, R. A. S., & Ten Cate-Hoek, A. J. (2024). Fibrinogen levels and clot properties identify patients that benefit from catheter-directed thrombolysis after DVT. Blood advances. Advance online publication. https://doi.org/10.1182/bloodadvances.2023012493
    • Baker, R. I., Choi, P., Curry, N., Gebhart, J., Gomez, K., Henskens, Y., Heubel-Moenen, F., James, P., Abdul Kadir, R., Kouides, P., Lavin, M., Lordkipanidze, M., Lowe, G., Mumford, A., Mutch, N., Nagler, M., Othman, M., Pabinger, I., Sidonio, R., ... ISTH SSC Von Willebrand Factor, Platelet Physiology and Women’s Health Issues in Thrombosis and Haemostasis. (2024). Standardisation of Definition and Management for Bleeding Disorder of Unknown Cause: Communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis. Advance online publication. https://doi.org/10.1016/j.jtha.2024.03.005
    • Busch, M. H., Ysermans, R., Aendekerk, J., Timmermans, S. A., Potjewijd, J., Damoiseaux, J., Spronk, H. M. H., Ten Cate, H., Reutelingsperger, C., Nagy, M., & van Paassen, P. (2024). The intrinsic coagulation pathway plays a dominant role in driving hypercoagulability in ANCA-Associated Vasculitis. Blood advances, 8(5), 1295-1304. https://doi.org/10.1182/bloodadvances.2023011937
    • Willems, R. A. L., Biesmans, C., Campello, E., Simioni, P., de Laat, B., de Vos-Geelen, J., Roest, M., & Ten Cate, H. (2024). Cellular Components Contributing to the Development of Venous Thrombosis in Patients with Pancreatic Cancer. Seminars in Thrombosis and Hemostasis, 50(3), 429-442. https://doi.org/10.1055/s-0043-1777304
    • Provenzale, I., Solari, F. A., Schoenichen, C., Brouns, S. L. N., Fernandez, D. I., Kuijpers, M. J. E., van Der Meijden, P. E. J., Gibbins, J. M., Sickmann, A., Jones, C., & Heemskerk, J. W. M. (2024). Endothelium-mediated regulation of platelet activation: Involvement of multiple protein kinases. Faseb Journal, 38(4), Article e23468. https://doi.org/10.1096/fj.202300360RR
    • Hulshof, A. M., Nab, L., van Rosmalen, F., de Kok, J., Mulder, M. M. G., Hellenbrand, D., Sels, J. W. E. M., ten Cate, H., Cannegieter, S. C., Henskens, Y. M. C., & van Bussel, B. C. T. (2024). Rotational thromboelastometry as a biomarker for mortality — The Maastricht Intensive Care COVID cohort. Thrombosis Research, 234, 51-58. https://doi.org/10.1016/j.thromres.2023.12.010
    • Iding, A. F. J., Limpens, T. M. P., Ten Cate, H., & Ten Cate-Hoek, A. J. (2024). Chronic inflammatory diseases increase the risk of post-thrombotic syndrome: A prospective cohort study. European journal of internal medicine, 120, 85-91. https://doi.org/10.1016/j.ejim.2023.10.014
    • Prandoni, P., Haas, S., Fluharty, M. E., Schellong, S., Gibbs, H., Tse, E., Carrier, M., Jacobson, B., ten Cate, H., Panchenko, E., Verhamme, P., Pieper, K., Kayani, G., Kakkar, L. A., & GARFIELD-VTE Investigators (2024). Incidence and predictors of post-thrombotic syndrome in patients with proximal DVT in a real-world setting: findings from the GARFIELD-VTE registry. Journal of Thrombosis and Thrombolysis, 57(2), 312-321. https://doi.org/10.1007/s11239-023-02895-7
    • Reutelingsperger, C. P. M., Gijbels, M. J., Spronk, H., Van Oerle, R., Schrijver, R., Ekhart, P., de Kimpe, S., & Nicolaes, G. A. F. (2024). M6229 Protects against Extracellular-Histone-Induced Liver Injury, Kidney Dysfunction, and Mortality in a Rat Model of Acute Hyperinflammation. International Journal of Molecular Sciences, 25(3), Article 1376. https://doi.org/10.3390/ijms25031376
    • Olie, R. H., Winckers, K., Rocca, B., & Ten Cate, H. (2024). Oral Anticoagulants Beyond Warfarin. Annual Review of Pharmacology and Toxicology, 64, 551-575. https://doi.org/10.1146/annurev-pharmtox-032823-122811
    • Baaten, C. C. F. M. J., Nagy, M., Bergmeier, W., Spronk, H. M. H., & van der Meijden, P. E. J. (2024). Platelet biology and function: plaque erosion vs. rupture. European Heart Journal, 45(1), 18-31. https://doi.org/10.1093/eurheartj/ehad720
    • Drozdinsky, G., Arad, N., Spectre, G., Livneh, N., Poran, I., Raanani, P., Falanga, A., ten Cate, H., Gafter-Gvili, A., & Leader, A. (2024). Anticoagulation in cancer patients with atrial fibrillation and grade 3–4 thrombocytopenia. Thrombosis Research, 235, 92-97. https://doi.org/10.1016/j.thromres.2024.01.012
  • 2023
    • Mulder, M. M. G., Schellens, J., Sels, J.-W. E. M., van Rosmalen, F., Hulshof, A.-M., de Vries, F., Segers, R., Mihl, C., van Mook, W. N. K. A., Bast, A., Spronk, H. M. H., Henskens, Y. M. C., van der Horst, I. C. C., ten Cate, H., Schurgers, L. J., Drent, M., & van Bussel, B. C. T. (2023). Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort. Journal of Intensive Care, 11(1), Article 63. https://doi.org/10.1186/s40560-023-00712-0
    • Van Voorst, H., Hoving, J. W., Koopman, M. S., Daems, J. D., Peerlings, D., Buskens, E., Lingsma, H., Marquering, H. A., De Jong, H. W. A. M., Berkhemer, O. A., Van Zwam, W. H., Van Walderveen, M. A. A., Van Den Wijngaard, I. R., Dippel, D. W. J., Yoo, A. J., Campbell, B., Kunz, W. G., Majoie, C. B., Emmer, B. J., ... MR CLEAN Registry Investigators (2023). Costs and health effects of CT perfusion-based selection for endovascular thrombectomy within 6 hours of stroke onset: a model-based health economic evaluation. Journal of Neurology Neurosurgery and Psychiatry. Advance online publication. https://doi.org/10.1136/jnnp-2023-331862
    • Verheugt, F. W. A., Fox, K. A. A., Virdone, S., Ambrosio, G., Gersh, B. J., Haas, S., Pieper, K. S., Kayani, G., Camm, A. J., Parkhomenko, A., Misselwitz, F., Ragy, APH., Ten Cate, H., Keltai, M., Kakkar, A. K., & GARFIELD-AF Investigators (2023). Outcomes of Oral Anticoagulation in Atrial Fibrillation Patients with or without Comorbid Vascular Disease: Insights from the GARFIELD-AF Registry. The American Journal of Medicine, 136(12), 1187-1195.e15. https://doi.org/10.1016/j.amjmed.2023.08.019
    • Sun, S., Campello, E., Zou, J., Konings, J., Huskens, D., Wan, J., Fernández, D. I., Reutelingsperger, C., Ten Cate, H., Toffanin, S., Bulato, C., de Groot, P. G., de Laat, B., Simioni, P., Heemskerk, J. W. M., & Roest, M. (2023). Crucial roles of red blood cells and platelets in whole blood thrombin generation. Blood advances, 7(21), 6717-6731. https://doi.org/10.1182/bloodadvances.2023010027
    • Van de Berg, T. W., Beckers, E. A. M., Heubel-Moenen, F. C. J. I., Henskens, Y. M. C., Thomassen, M. C. L. G. D., & Hackeng, T. M. (2023). Sensitive Measurement of Clinically Relevant Factor VIII Levels in Thrombin Generation Assays Requires Presence of Factor XIa. Thrombosis and Haemostasis, 123(11), 1034-1041. https://doi.org/10.1055/a-2101-7961
    • Jacobs, L. M. C., Wintjens, M. S. J. N., Nagy, M., Willems, L., ten Cate, H., Spronk, H. M. H., van Kuijk, S. M. J., Ghossein-Doha, C., Netea, M. G., Groh, L. A., van Petersen, A. S., & Warle, M. C. (2023). Biomarkers of sustained systemic inflammation and microvascular dysfunction associated with post-COVID-19 condition symptoms at 24 months after SARS-CoV-2-infection. Frontiers in Immunology, 14(1), Article 1182182. https://doi.org/10.3389/fimmu.2023.1182182
    • Heuts, S., Ceulemans, A., Kuiper, G. J. A. J. M., Schreiber, J. U., van Varik, B. J., Olie, R. H., Ten Cate, H., Maessen, J. G., Milojevic, M., & Maesen, B. (2023). Optimal management of cardiac surgery patients using direct oral anticoagulants: recommendations for clinical practice. European Journal of Cardio-Thoracic Surgery, 64(4), Article ezad340. https://doi.org/10.1093/ejcts/ezad340
    • V. Kock, R., Berend, K., Florquin, S., & ten Cate, H. (2023). Pitfalls in anticoagulant-related nephropathy. Clinical Nephrology, 100(6), 284-289. https://doi.org/10.5414/CN111156
    • Baidildinova, G., Pallares Robles, A., ten Cate, V., Kremers, B. M. M., Heitmeier, S., ten Cate, H., Mees, B. M. E., Spronk, H. M. H., Wild, P. S., ten Cate-Hoek, A. J., & Jurk, K. (2023). Plasma protein signatures for high on-treatment platelet reactivity to aspirin and clopidogrel in peripheral artery disease. Thrombosis Research, 230(1), 105-118. https://doi.org/10.1016/j.thromres.2023.08.017
    • Alnima, T., Meijer, R. I., Spronk, H. M. H., Warlé, M., & Cate, H. T. (2023). Diabetes- versus smoking-related thrombo-inflammation in peripheral artery disease. Cardiovascular Diabetology, 22(1), Article 257. https://doi.org/10.1186/s12933-023-01990-6
    • Denessen, E. J. S., Vroemen, W. H. M., Litjens, E. J. R., Henskens, Y. M. C., van der Sande, F. M., Bekers, O., de Boer, D., & Mingels, A. M. A. (2023). Cardiac Troponin T Degradation in End-Stage Renal Disease Patients Appears to Occur in Vivo. Journal of Applied Laboratory Medicine, 8(5), 1000-1002. https://doi.org/10.1093/jalm/jfad043
    • Provenzale, I., De Simone, I., Gibbins, J. M., Heemskerk, J. W. M., van der Meijden, P. E. J., & Jones, C. I. (2023). Regulation of Glycoprotein VI-Dependent Platelet Activation and Thrombus Formation by Heparan Sulfate Proteoglycan Perlecan. International Journal of Molecular Sciences, 24(17), Article 13352. https://doi.org/10.3390/ijms241713352
    • Schönichen, C., Montague, S. J., Brouns, S. L. N., Burston, J. J., Cosemans, J. M. E. M., Jurk, K., Kehrel, B. E., Koenen, R. R., Ní Áinle, F., O'Donnell, V. B., Soehnlein, O., Watson, S. P., Kuijpers, M. J. E., Heemskerk, J. W. M., & Nagy, M. (2023). Antagonistic Roles of Human Platelet Integrin aIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow. Arteriosclerosis Thrombosis and Vascular Biology, 43(9), 1700-1712. https://doi.org/10.1161/ATVBAHA.122.318767
    • Gigante, B., Levy, J. H., van Gorp, E., Bartoloni, A., Bochaton-Piallat, M.-L., Bäck, M., Ten Cate, H., Christersson, C., Ferreiro, J. L., Geisler, T., Lutgens, E., Schulman, S., Storey, R. F., Thachil, J., Vilahur, G., Liaw, P. C., & Rocca, B. (2023). Management of patients on antithrombotic therapy with severe infections: a joint clinical consensus statement of the ESC Working Group on Thrombosis, the ESC Working Group on Atherosclerosis and Vascular Biology, and the International Society on Thrombosis and Haemostasis. European Heart Journal, 44(32), 3040-3058. https://doi.org/10.1093/eurheartj/ehad388
    • Manukjan, N., Majcher, D., Leenders, P., Caiment, F., van Herwijnen, M., Smeets, H. J. J., Suidgeest, E., van der Weerd, L., Vanmierlo, T., Jansen, J. F. A., Backes, W. H. H., van Oostenbrugge, R. J. J., Staals, J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment. Acta neuropathologica communications, 11(1), Article 128. https://doi.org/10.1186/s40478-023-01627-5
    • Schultinge, L., Hulshof, A. M., van Neerven, D., Mulder, M. M. G., Sels, J. W. E. M., Hulsewe, H. P. M. G., Kuiper, G. J. A. J. M., Olie, R. H., ten Cate, H., van der Horst, I. C. C., van Bussel, B. C. T., & Henskens, Y. M. C. (2023). Applications of rotational thromboelastometry in heparin monitoring in critical COVID-19 disease: Observations in the Maastricht Intensive Care COVID cohort. Thrombosis Update, 12(1), Article 100140. https://doi.org/10.1016/j.tru.2023.100140
    • Luu, I. H. Y., Buijs, J., Krdzalic, J., de Kruif, M. D., Mostard, G. J. M., ten Cate, H., Dormans, T. P. J., Mostard, R. L. M., Leers, M. P. G., & van Twist, D. J. L. (2023). Pulmonary embolism in hospitalized COVID-19 patients: Short- and long-term clinical outcomes. Thrombosis Update, 12(1), Article 100142. https://doi.org/10.1016/j.tru.2023.100142
    • Schol, P. B. B., de Lange, N., Henskens, Y., Smits, L. J. M., Smeets, N. A. C., & Scheepers, H. C. J. (2023). Restrictive versus liberal fluid administration strategy (REFILL study) in postpartum hemorrhage and its effects on thromboelastometry (ROTEM®) values: a randomized, controlled trial. Journal of International Medical Research, 51(8), Article 03000605231171007. https://doi.org/10.1177/03000605231171007
    • Fernandez, D. I., Diender, M., Hermida-Nogueira, L., Huang, J., Veiras, S., Henskens, Y. M. C., te Loo, M. W. M., Heemskerk, J. W. M., Kuijpers, M. J. E., & Garcia, A. (2023). Role of SHP2 (PTPN11) in glycoprotein VI-dependent thrombus formation: Improved platelet responsiveness by the allosteric drug SHP099 in Noonan syndrome patients. Thrombosis Research, 228(1), 105-116. https://doi.org/10.1016/j.thromres.2023.06.001
    • Musgrave, K. M., Scott, J., Sendama, W., Gardner, A. I., Dewar, F., Lake, C. J., Spronk, H. M. H., van Oerle, R., Visser, M., ten Cate, H., Kesteven, P., Fuller, A., McDonald, D., Knill, C., Hulme, G., Filby, A., Wright, S. E., Roy, A. I., Ruchaud-Sparagano, M.-H., ... Rostron, A. J. (2023). Tissue factor expression in monocyte subsets during human immunothrombosis, endotoxemia and sepsis. Thrombosis Research, 228(1), 10-20. https://doi.org/10.1016/j.thromres.2023.05.018
    • Gigante, B., & Cate, H. T. (2023). Factor XI inhibitors in patients with cardiovascular disease and a high risk of bleeding: a cautionary tale. Nature Reviews Cardiology, 20(8), 511-512. https://doi.org/10.1038/s41569-023-00872-4
    • Iding, A. F. J., Kremers, B. M. M., Pallares Robles, A., ten Cate, H., & ten Cate-Hoek, A. J. (2023). Residual Venous Obstruction as an Indicator of Clinical Outcomes following Deep Vein Thrombosis: A Management Study. Thrombosis and Haemostasis, 123(08), 763-772. https://doi.org/10.1055/a-2059-4737
    • Douxfils, J., ten Cate, H., & Pola, R. (2023). Insights in thrombosis: 2022. Frontiers in Cardiovascular Medicine, 10(1), Article 1240626. https://doi.org/10.3389/fcvm.2023.1240626
    • Kerkhofs, D., Helgers, R., Hermes, D., Steinbusch, H. P. J., Van Essen, H., Leenders, P., Prickaerts, J., Staals, J., Biessen, E. A., Van Oostenbrugge, R. J., & Foulquier, S. (2023). Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice. Journal of Hypertension, 41(7), 1159-1167. https://doi.org/10.1097/HJH.0000000000003445
    • Robles, A. P., ten Cate, V., Lenz, M., Schulz, A., Prochaska, J. H., Rapp, S., Koeck, T., Leineweber, K., Heitmeier, S., Opitz, C. F., Held, M., Espinola-Klein, C., Lackner, K. J., Muenzel, T., V. Konstantinides, S., ten Cate-Hoek, A., ten Cate, H., & Wild, P. S. (2023). Unsupervised clustering of venous thromboembolism patients by clinical features at presentation identifies novel endotypes that improve prognostic stratification. Thrombosis Research, 227(1), 71-81. https://doi.org/10.1016/j.thromres.2023.04.023
    • Willems, R. A. L., Michiels, N., Lanting, V. R., Bouwense, S., van den Broek, B. L. J., Graus, M., Klok, F. A., Koerkamp, B. G., de Laat, B., Roest, M., Wilmink, J. W., van Es, N., Mieog, J. S. D., ten Cate, H., & de Vos-Geelen, J. (2023). Venous Thromboembolism and Primary Thromboprophylaxis in Perioperative Pancreatic Cancer Care. Cancers, 15(14), Article 3546. https://doi.org/10.3390/cancers15143546
    • Nagy, M., Robles, A. P., Visser, M., Koeck, T., ten Cate, V., ten Cate-Hoek, A. J., Schwers, S., Heitmeier, S., ten Cate, H., Wild, P. S., & Spronk, H. M. H. (2023). Predictive value for increased activated factor XI activity in acute venous thromboembolism. Journal of Thrombosis and Haemostasis, 21(6), 1610-1622. https://doi.org/10.1016/j.jtha.2023.02.031
    • Jooss, N. J., Henskens, Y. M. C., Watson, S. P., Farndale, R. W., Gawaz, M. P., Jandrot-Perrus, M., Poulter, N. S., & Heemskerk, J. W. M. (2023). Pharmacological Inhibition of Glycoprotein VI- and Integrin α2β1-Induced Thrombus Formation Modulated by the Collagen Type. Thrombosis and Haemostasis, 123(06), 597-612. https://doi.org/10.1055/s-0043-1761463
    • Akbalut, C., Arisz, R., Baaten, C., Baildildinova, G., Barakzie, A., Bauersachs, R., Ten Berg, J. M., van den Broek, W., de Boer, H. C., Broker, V., Buka, R., Ten Cate, H., Cate, A. T., De Luca, C., De Simone, I., Dignat-George, F., Freson, K., Gazzaniga, G., van Gorp, E., ... van Zonneveld, A.-J. (2023). Blood coagulation and beyond: Position paper from the Fourth Maastricht Consensus Conference on Thrombosis. Thrombosis and Haemostasis, 123(8), 808-839. https://doi.org/10.1055/a-2052-9175
    • Braeken, D. C. W., Bavalia, R., Henskens, Y. M. C., Cate, H. T., Hengeveld, R. C. C., Hutten, B. A., Middeldorp, S., Coppens, M., & Stroobants, A. K. (2023). Clinical characteristics of patients with direct oral anticoagulant (DOAC) levels outside expected ranges: A retrospective chart study. Thrombosis Update, 11(1), Article 100139. https://doi.org/10.1016/j.tru.2023.100139